A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
RG7-0099 is a small-molecule and dual inhibitor of IDO1/TDO (IDO1 IC50 < 100nM while TDO IC50 < 100nM) , which modulate immunosuppressive effects. In preclinical models, it significantly reduced Kyn levels. RG7-0099 is potentially used in various cancers. Uses: Potential antitumor drug. Synonyms: RG7-0099; RG7 0099; RG70099.
RG7090
RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5). Synonyms: Basimglurant; CTEP Derivative; RG7090; RG 7090; RG-7090. Grades: >98%. CAS No. 802906-73-6. Molecular formula: C18H13ClFN3. Mole weight: 325.77.
RG7129
Cas No. 1628077-06-4.
RG7800
RG7800 is a selective Survival of motor neuron 1 protein (SMN1) stimulant and Survival of motor neuron 2 protein (SMN2) modulator originated by Roche. RG7800 shows excellent pharmacokinetic and in vivo efficacy and has a favorable safety profile. RG7800 can correct alternative splicing of the human. Phase I/II clinical trials for the treatment of Spinal muscular atrophyis on-going. Uses: Spinal muscular atrophy. Synonyms: RG7800; RG-7800; RG 7800; RO6885247; RO-6885247; RO 6885247. 2-(4-ethyl-6-methylpyrazolo[1,5-a]pyrazin-2-yl)-9-methyl-7-(1-methylpiperidin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: 98%. CAS No. 1449598-06-4. Molecular formula: C24H28N6O. Mole weight: 416.52.
RG7834
RG7834 is a highly selective and orally bioavailable HBV inhibitor, suppressing HBV antigens (both HBsAg and HBeAg) and virion production. Synonyms: RO 7020322; (6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydro-2h-pyrido[2,1-a]isoquinoline-3-carboxylic acid. Grades: ≥98% (HPLC). CAS No. 2072057-17-9. Molecular formula: C22H27NO6. Mole weight: 401.45.
RGA-C11
Non-ionic Detergents. Alternative Names: Resorcinarene-based amphiphile-C11. CAS No. 2390023-16-0. Molecular formula: C132H216O56. Mole weight: 2699.09. Appearance: Powder.
RGA-C11
It is a mild glucoside detergent that can be used as an alternative to GDN, digitalin and CHAPS. Due to the formation of small protein-detergent complexes (PDCs) with GPCRs and their enhanced stability, this detergent is conducive to the determination of protein structures, particularly for CryoEM-based structural study. Synonyms: resorcinarene-based amphiphile-C11. Grades: >99%. CAS No. 2390023-16-0. Molecular formula: C132H216O56. Mole weight: 2699.09.
Rga I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCGAT↑CGC CGC↓TAGCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Rhizoblum galegae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1164RE.
RGB-1
RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 930455-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156228.
RGB-286638
RGB-286638 is a novel CDK inhibitor. It inhibited several tyrosine and serine/threonine non-CDK enzymes, i.e. GSK-3β, TAK1, AMPK, Jak2, MEK1. It demonstrated equimolar (50nM) activity in freshly isolated tumor cells from MM patients, while manifesting less cytotoxicity in healthy donor PBMCs. It reduced the phosphorylation of Rb at S807/811 in MM.1S and MM.1R cells, but had no effects on p-Rb S780. Synonyms: RGB-286638; RGB286638; RGB286638. Grades: >98%. CAS No. 784210-87-3. Molecular formula: C29H37Cl2N7O4. Mole weight: 618.55.
RGB-286638 free base
RGB-286638 is a multitargeted cyclin-dependent kinase inhibitor. RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs. GB-286638 treatment resulted in MM cytotoxicity in vitro associated with inhibition of MM tumor growth and prolonged survival in vivo. RGB-286638 displayed caspase-dependent apoptosis in both wt-p53 and mutant-p53 cells that was closely associated with the downregulation of RNA polymerase II phosphorylation and inhibition of transcription. RGB-286638 triggered p53 accumulation via nucleolar stress and loss of Mdm2, accompanied by induction of p53 DNA-binding activity. Group: Inhibitors. Alternative Names: RGB-286638, RGB 286638, RGB286638; RGB-286638 free base. CAS No. 784210-88-4. Molecular formula: C29H35N7O4. Mole weight: 545.64. Appearance: Solid powder. Purity: >98%. IUPACName: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea. Canonical SMILES: O=C (NN1CCOCC1)NC2=CC=CC (C3=C4C (C5=CC=C (CN6CCN (CCOC)CC6)C=C5)=NN3)=C2C4=O. Catalog: ACM784210884.
RGB-286638 Free base
RGB-286638 is a novel CDK inhibitor. It inhibited several tyrosine and serine/threonine non-CDK enzymes, i.e. GSK-3β, TAK1, AMPK, Jak2, MEK1. It demonstrated equimolar (50nM) activity in freshly isolated tumor cells from MM patients, while manifesting less cytotoxicity in healthy donor PBMCs. It reduced the phosphorylation of Rb at S807/811 in MM.1S and MM.1R cells, but had no effects on p-Rb S780. Synonyms: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea; RGB 286638; RGB286638. Grades: >98%. CAS No. 784210-88-4. Molecular formula: C29H35N7O4. Mole weight: 545.63.
RGD
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 99896-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0278.
RGD-4C
RGD-4C preferentially binds to integrins αvβ3 and αvβ5, both of which are overexpressed in many cancers, such as non-small cell lung cancer, melanoma, and growing vessels. Synonyms: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); L-alanyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-arginyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-glycine (2->10),(4->8)-bis(disulfide); N-{[(1R,4S,7R,12R,15S,18R,21S,27S)-7-(L-Alanylamino)-15-benzyl-27-(3-carbamimidamidopropyl)-4,21-bis(carboxymethyl)-3,6,14,17,20,23,26,29-octaoxo-9,10,31,32-tetrathia-2,5,13,16,19,22,25,28-octaazabicyclo[16.11.4]tritriacont-12-yl]carbonyl}glycine. Grades: ≥95%. CAS No. 332179-76-7. Molecular formula: C42H60N14O16S4. Mole weight: 1145.29.
RGD Negative Control
It is the negative control of c(RGDfE). Synonyms: c(RADfE); cyclo[Ala-Asp-D-Phe-Glu-Arg]; cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl-L-arginyl]. Grades: ≥95%. CAS No. 756500-24-0. Molecular formula: C27H38N8O9. Mole weight: 618.65.
RGD peptide
RGD peptide is an inhibitor of integrin-ligand interactions. Synonyms: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. Grades: 98%. CAS No. 114681-65-1. Molecular formula: C23H38N10O10. Mole weight: 614.61.
RGD peptide (GRGDNP)
RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 114681-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1740.
RGD-targeted Proapoptotic Peptide
RGD-targeted Proapoptotic Peptide is RGD-4C conjugated to a full D proapoptotic peptide. Synonyms: RGD-4C-GG-(klaklak)2-NH2; H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic(2?10),(4?8)-bis(disulfide). Grades: ≥95%. CAS No. 2243207-09-0. Molecular formula: C116H199N35O31S4. Mole weight: 2708.34.
RGD Trifluoroacetate
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 2378808-45-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0278A.
RGFP966
RGFP966 is a selective HDAC3 inhibitor. Systemic treatment with RGFP966 facilitates extinction in mice in a manner resistant to reinstatement. A single treatment of RGFP966 enhances extinction of a previously established cocaine-conditioned place preference, while simultaneously enhancing long-term object-location memory within subjects. During extinction consolidation, HDAC3 inhibition promotes a distinct pattern of histone acetylation linked to gene expression within the infralimbic cortex, hippocampus, and nucleus accumbens. Thus, the facilitated extinction of drug-seeking cannot be explained by adverse effects on performance. These results demonstrate that HDAC3 inhibition enhances the memory processes involved in extinction of drug-seeking behavior. Synonyms: RGFP966; RGFP 966; RGFP-966. Grades: 0.98. CAS No. 1357389-11-7. Molecular formula: C21H19FN4O. Mole weight: 362.4.
RGS Proteins Inhibitor II, CCG-50014 (4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione)
A cell-permeable thiadiazolidinedione compound that acts as a direct, potent, selective and cysteine-reactive irreversible inhibitor of RGS4 over other RGS proteins (IC50=0.03, 0.12, 3.5, 11, >200 and >200uM against RGS4, RGS19, RGS16, RGS8, RGS7 and RGS4Cys- using FCPIA assay, respectively). Shown to block RGS4-Ga0 interaction and repress Ga0-dependent membrane localization of RGS4 in HEK-293T cells with no effect on the intrinsic rate of GTP hydrolysis by Ga0. Suggested to interact with Cys107-RGS8 allosteric regulatory site and display minimal affinity towards papain (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RGW2938
A phosphodiesterase inhibitor. Synonyms: RGW2938; RGW 2938; RGW-2938; 2(1H)?-Quinazolinone, 3,?4-dihydro-3-methyl-6-(1,?4,?5,?6-tetrahydro-6-oxo-3-pyridazinyl)?-. CAS No. 111786-07-3. Molecular formula: C13H14N4O2. Mole weight: 258.28.
RGW 611
RGW 611 is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. Nimorazole is being researched for the treatment of head and neck cancer. Synonyms: 4-(2-(4-nitro-1H-imidazol-1-yl)ethyl)morpholine. CAS No. 6497-78-5. Molecular formula: C9H14N4O3. Mole weight: 226.236.
RGX-104
RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abequolixron. CAS No. 610318-54-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111498A.
RGX-104 hydrochloride
RGX-104 is an orally bioavailable liver X receptor agonist displaying immunomodulating and antineoplastic activity. Synonyms: RGX-104; 2-[3-[ (3R) -3-[[2-Chloro-3- (trifluoromethyl) phenyl]methyl- (2, 2-diphenylethyl) amino]butoxy]phenyl]acetic acid hydrochloride. CAS No. 610318-03-1. Molecular formula: C34H34Cl2F3NO3. Mole weight: 632.54.
RGX-104 hydrochloride
RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abequolixron hydrochloride. CAS No. 610318-03-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111498.
RH1
RH1 is a new bioreductive agent that is an excellent substrate for the two-electron reducing enzyme, NAD(P)H quinone oxidoreductase 1 (NQO1). In phase trials, RH1 was well tolerated with predictable and manageable toxicity. The MTD of 1430 μg/m(2)/day is the dose recommended for phase II trials. The biomarkers of DNA cross linking, DTD activity and NQO1 status have been validated and clinically developed. Synonyms: RH 1; RH-1; NSC697726; 2,5-di(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione. CAS No. 221635-42-3. Molecular formula: C12H14N2O3. Mole weight: 234.25.
RH1
RH1 (NSC 697726) is a potent bioreductive agent with profound anti-cancer activity in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 697726. CAS No. 221635-42-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13741.
RH-5849
RH-5849 is an orally active agonist for non-steroidal ecdysteroid , which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112225-87-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g; 5 g. Product ID: HY-118541.
Rhacophorin-1 antimicrobial peptide precursor
Rhacophorin-1 antimicrobial peptide precursor is an antibacterial peptide isolated from Rhacophorus feae. Synonyms: Ile-Gly-Pro-Met-Ile-Lys-Ile-Ala-Thr-Asn-Leu-Leu-Pro-Thr-Val-Ile-Cys-Lys-Ile-Phe-Lys-Lys-Cys. Grades: >96%.
Rhacophorin-2 antimicrobial peptide precursor
Rhacophorin-2 antimicrobial peptide precursor is an antibacterial peptide isolated from Rhacophorus feae. Synonyms: Thr-Leu-Lys-Lys-Ser-Leu-Leu-Ile-Leu-Phe-Phe-Leu-Gly-Met-Ile-Ser-Met-Ser-Leu-Cys-Gln. Grades: >96%.
Rhamnetin
Rhamnetin is a quercetin derivative found in Coriandrum sativum , inhibits secretory phospholipase A2 , with antioxidant and anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-19-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7036.
rhamnogalacturonan acetylesterase
The degradation of rhamnogalacturonan by rhamnogalacturonases depends on the removal of the acetyl esters from the substrate. Group: Enzymes. Synonyms: RGAE. Enzyme Commission Number: EC 3.1.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3515; rhamnogalacturonan acetylesterase; EC 3.1.1.86; RGAE. Cat No: EXWM-3515.
rhamnogalacturonan endolyase
The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168 and Aspergillus aculeatus. Group: Enzymes. Synonyms: rhamnogalacturonase B; α-L-rhamnopyranosyl-(1?4)-α-D-galactopyranosyluronide lyase; Rgase B; rhamnogalacturonan α-L-rhamnopyranosyl-(1,4)-α-D-galactopyranosyluronide lyase; RG-lyase; YesW; RGL4; Rgl11A; Rgl11Y; RhiE. Enzyme Commission Number: EC 4.2.2.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5099; rhamnogalacturonan endolyase; EC 4.2.2.23; rhamnogalacturonase B; α-L-rhamnopyranosyl-(1?4)-α-D-galactopyranosyluronide lyase; Rgase B; rhamnogalacturonan α-L-rhamnopyranosyl-(1,4)-α-D-galactopyranosyluronide lyase; RG-lyase; YesW; RGL4; Rgl11A; Rgl11Y; RhiE. Cat No: EXWM-5099.
rhamnogalacturonan exolyase
The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168. Group: Enzymes. Synonyms: YesX. Enzyme Commission Number: EC 4.2.2.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5100; rhamnogalacturonan exolyase; EC 4.2.2.24; YesX. Cat No: EXWM-5100.
Rhamnogalacturonan - from potato
Rhamnogalacturonan - from soy bean
rhamnogalacturonan galacturonohydrolase
The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: RG-galacturonohydrolase. Enzyme Commission Number: EC 3.2.1.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3856; rhamnogalacturonan galacturonohydrolase; EC 3.2.1.173; RG-galacturonohydrolase. Cat No: EXWM-3856.
rhamnogalacturonan hydrolase
The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: rhamnogalacturonase A; RGase A; RG-hydrolase. Enzyme Commission Number: EC 3.2.1.171. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3854; rhamnogalacturonan hydrolase; EC 3.2.1.171; rhamnogalacturonase A; RGase A; RG-hydrolase. Cat No: EXWM-3854.
Rhamnogalacturonan Lyase from Cellvibrio japonicus, Recombinant
Rhamnogalacturonan Lyase is an endo-1,4-α-rhamnogalacturonan lyase. This enzyme catalyses the following chemical reaction: Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end. Group: Enzymes. Synonyms: endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Enzyme Commission Number: EC 4.2.2.-. Purity: >90% as judged by SDS-PAGE. Rhamnogalacturonan Lyase. Mole weight: 79.6 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Cellvibrio japonicus. endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Cat No: NATE-1565.
Rhamnogalacturonan Lyase from Clostridium thermocellum, Recombinant
Rhamnogalacturonan Lyase is an endo-1,4-α-rhamnogalacturonan lyase. This enzyme catalyses the following chemical reaction: Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end. Group: Enzymes. Synonyms: endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Enzyme Commission Number: EC 4.2.2.-. Purity: >90% as judged by SDS-PAGE. Rhamnogalacturonan Lyase. Mole weight: 76.1 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Clostridium thermocellum. endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Cat No: NATE-1564.
rhamnogalacturonan rhamnohydrolase
The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: RG-rhamnohydrolase; RG α-L-rhamnopyranohydrolase. Enzyme Commission Number: EC 3.2.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3857; rhamnogalacturonan rhamnohydrolase; EC 3.2.1.174; RG-rhamnohydrolase; RG α-L-rhamnopyranohydrolase. Cat No: EXWM-3857.
Rhamnolipid
Rhamnolipid is a versatile bioproduct widely used in the biomedical industry known for its exceptional surface-active and antimicrobial properties. Rhamnolipid has been extensively studied for its potential in studying various drug-resistant infections and diseases. Moreover, this natural surfactant exhibits promising potential as an eco-friendly alternative in pharmaceutical formulations and drug delivery systems. Synonyms: Rha-(rac)C10C10 rhamnolipid; mono-Rhamnolipid. Molecular formula: C26H48O9. Mole weight: 504.65.
Isolated from Mycobacterium tuberculosis and M. smegmatis, the enzyme has dual β-(1?4) and β-(1?5) transferase action. Involved in the formation of the cell wall in mycobacteria. Group: Enzymes. Synonyms: arabinogalactan galactofuranosyl transferase 1; GlfT1. Enzyme Commission Number: EC 2.4.1.287. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2520; rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol β-1,3/1,4-galactofuranosyltransferase; EC 2.4.1.287; arabinogalactan galactofuranosyl transferase 1; GlfT1. Cat No: EXWM-2520.
Rhamnose
Rhamnose (L-Rhamnose) is an orally active deoxysugar that is widely found in plants and bacteria. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases ( MMPs ) in skin aging models, showing anti-aging effects. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose is also used in cancer research [2] [3] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Rhamnose. CAS No. 3615-41-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N1420.
Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies [1]. Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption [2]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Rhamnose monohydrate. CAS No. 10030-85-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1420A.
Rhamnoside
Rhamnoside. Uses: For analytical and research use. Group: Impurity standards. CAS No. 23202-85-9. Molecular Formula: C26H32O11. Mole Weight: 520.53. Catalog: APB23202859.
rhamnulokinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:L-rhamnulose 1-phosphotransferase. Other names in common use include RhuK, rhamnulokinase (phosphorylating), L-rhamnulokinase, L-rhamnulose kinase, and rhamnulose kinase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism. Group: Enzymes. Synonyms: RhuK; rhamnulokinase (phosphorylating); L-rhamnulokinase; L-rhamnulose kinase; rhamnulose kinase. Enzyme Commission Number: EC 2.7.1.5. CAS No. 9030-52-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3080; rhamnulokinase; EC 2.7.1.5; 9030-52-8; RhuK; rhamnulokinase (phosphorylating); L-rhamnulokinase; L-rhamnulose kinase; rhamnulose kinase. Cat No: EXWM-3080.
rhamnulose-1-phosphate aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism. Group: Enzymes. Synonyms: rhamnulose phosphate aldolase; L-rhamnulose 1-phosphate aldolase; L-rhamnulose-phosphate aldolase; L-rhamnulose-1-phosphate lactaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.19. CAS No. 9054-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4857; rhamnulose-1-phosphate aldolase; EC 4.1.2.19; 9054-58-4; rhamnulose phosphate aldolase; L-rhamnulose 1-phosphate aldolase; L-rhamnulose-phosphate aldolase; L-rhamnulose-1-phosphate lactaldehyde-lyase. Cat No: EXWM-4857.
Rhapontic Rhubarb Extract
Rheum Rhaponticum (Rhubarb) root extract. Shown to regulate skin desquamation and restore skin moisturization. Contains rhaponticin and hydroxystilbenes which increase the levels of filaggrin and involucrin that are known to improve the cohesion of the stratum corneum and the barrier function of the skin. Improves the lipid barrier of the skin, protecting the body from the exterior and preventing skin dehydration. Uses: Bath gels, body milks, hand creams, hair care products, shampoos, lotions, conditioners, masks, make-up and sun care products. Group: Skin actives. CAS No. 26264-14-2/7732-18-5/90106-29-9. Catalog: CI-SC-0619.
Rhaponticum Carthamoides P.E. 100:1
Rhaponticum Carthamoides P.E. 100:1.
CA, FL & NJ
Rhaponticum Carthanmoides P. E. 5% Beta Ecdysterone HPLC
Rhaponticum Carthanmoides P. E. 5% Beta Ecdysterone HPLC.
CA, FL & NJ
Rhapontigenin
Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively. Group: Inhibitors. CAS No. 500-65-2. Molecular formula: C15H14O4. Mole weight: 258.3. Appearance: White powder. Purity: 0.98. IUPACName: 5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol. Canonical SMILES: COC1=C (C=C (C=C1)C=CC2=CC (=CC (=C2)O)O)O. Catalog: ACM500652.
Rhapontigenin
A natural analog of resveratrol with antioxidant and anti-cancer activity. Rhapontigenin was found to scavenge intracellular reactive oxygen species (ROS), the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, and hydrogen peroxide (H2O2). Rhapontigenin protected against H2O2-induced membrane lipid peroxidation and cellular DNA damage, which are the main targets of oxidative stress-induced cellular damage. Group: Biochemicals. Alternative Names: 5-[(1E)-2-(3-?hydroxy-4-methoxyphenyl)ethenyl]-1,?3-benzenediol. Grades: Highly Purified. CAS No. 500-65-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Rhapontigenin 3'-O-glucoside
Rhapontigenin 3'-O-glucoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 94356-22-6. Pack Sizes: 5mg. Molecular Formula: C21H24O9, Molecular Weight: 420.41. US Biological Life Sciences.
Worldwide
Rhapontin
Rhapontin (Rhaponiticin), a component of rhubarb ( Rheum officinale Baill), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Rhaponiticin. CAS No. 155-58-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-N0671.
Rhapontin
Rhapontin. Group: Biochemicals. Alternative Names: Ponticin; Rhaponticin. Grades: Plant Grade. CAS No. 155-58-8. Pack Sizes: 20mg. Molecular Formula: C21H24O9, Molecular Weight: 420.41. US Biological Life Sciences.
Worldwide
Rhapontin
100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C21H24O9. CAS No. 155-58-8. Prepack ID 47839775-100mg. Molecular Weight 420.41. See USA prepack pricing.
RhBD-1(32-67)
RhBD-1(32-67) is an antibacterial peptide isolated from Homo sapiens. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Asp-His-Tyr-Asn-Cys-Val-Arg-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Tyr-Thr-Arg-Ile-Gln-Gly-Thr-Cys-Tyr-His-Gly-Lys-Ala-Lys-Cys-Cys-Lys.
RHC 80267
RHC 80267 is a selective inhibitor of DAGL (IC50 values are 1.1 and 4 μM in rat cardiac myocytes and canine platelets respectively) that demonstrates relatively weak inhibition of phospholipases A2 and C. It potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC50 = 4 μM). Uses: Protease inhibitors. Synonyms: RHC80267; RHC 80267; RHC-80267; U 57908; U57908. O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone. Grades: ≥95% by HPLC. CAS No. 83654-05-1. Molecular formula: C20H34N4O4. Mole weight: 394.51.
RHC 80267
RHC 80267. Group: Biochemicals. Grades: Purified. CAS No. 83654-05-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RHC 80267
RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL) (with IC 50 of 4 μM in canine platelets). RHC-80267 inhibits cholinesterase activity with an IC 50 of 4 μM, thereby enhancing the relaxation evoked by acetylcholine. RHC 80267 also inhibits COX and the hydrolysis of phosphatidylcholine (PC) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-57908. CAS No. 83654-05-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107416.
Rhein
Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.IC50 value:Target:In vitro: Rhein (0.1 and 1 mg/mL) evidently suppressed cell proliferation and mitogen-activated protein (MAP) kinase activation in human colon adenocarcinoma cells (Caco-2) but significantly lessened H2O2-induced DNA damage and the elevated MDA and ROS levels induced by H2O2/Fe2+ at the concentrations of 0.1-10 mg/mL.In vivo: Oral administration of rhein (150 mg/kg/d) evidently ameliorated renal interstitial fibrotic lesions and attenuated the expression of α-SMA and deposition of fibronectin (FN) in mice with renal interstitial fibrosis induced by unilateral ureteral obstruction. Rhein also suppressed TGF-β1 and its type I receptor expression in obstructed kidneys. The biochemical parameters results of IgAN model rats showed that rhein-prevented and rhein-treated both improved the biochemical parameters and relieved renal pathological injury. The expressions of renal tissue TLR4, TGF-β1, but not TLR9 were significantly elevated in IgAN model rats (P < 0.05). Rhein-prevented and rhein-treated both inhibited TLR4 and TGF-β1 expressions. Group: Inhibitors. Alternative Names: Chrysazin-3-carboxylicacid. CAS No. 478-43-3. Molecular formula: C15H8O6. Mole weight: 284.22. A
Rhein
Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Rheic Acid; Rhubarb yellow; Monorhein. CAS No. 478-43-3. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-N0105.
Rhein
5g Pack Size. Group: Analytical Reagents, Bioactive Small Molecules, Biochemicals, Building Blocks, Organics. Formula: C15H8O6. CAS No. 478-43-3. Prepack ID 70203905-5g. Molecular Weight 284.22. See USA prepack pricing.
Rhein
Found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. A potential antioxidant resource: endophytic fungi from medicinal plants. Group: Biochemicals. Alternative Names: 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic Acid; 4, 5-Di hydroxy-2-anthraquinonecarboxyl ic Acid; Chrysazin-3-carboxylic Acid; Monorhein; NSC 38629; Rheic Acid; Rhubarb Yellow. Grades: Highly Purified. CAS No. 478-43-3. Pack Sizes: 25mg. US Biological Life Sciences.