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| Product | Description | |
|---|---|---|
| Reverse transcriptase-IN-1 | Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC 50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 III B , E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC 50 of 13.7 nM against HIV-1 reverse transcriptase enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380001-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130241. |  |
| Reversin 121 | Reversin 121 is a selective P-glycoprotein multidrug transporter (MDR1) inhibitor with Kd value of 77 nM. Synonyms: reversin 121; 174630-04-7; CHEMBL221390; tert-butyl (2S) -2-[[ (2S) -2-[ (2-methylpropan-2-yl) oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6- (phenylmethoxycarbonylamino) hexanoate; Boc-Asp(Obzl)-Lys(Z)-OtBu; BDBM50326927; DB14072; HY-125486; Reversin 121, >=97% (HPLC), powder; CS-0091919; (S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)-4-oxobutanamido)-6-(benzyloxycarbonylamino)hexanoate; tert-Butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate. Grades: ≥98%. CAS No. 174630-04-7. Molecular formula: C34H47N3O9. Mole weight: 641.8. |  |
| Reversine | Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC 50 s of 400, 500 and 400 nM for Aurora A , Aurora B and Aurora C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 656820-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14711. | |
| Reversine | Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Synonyms: Reversine; 656820-32-5; 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; CHEMBL188343; CHEBI:70723; C21H27N7O; N6-cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine; N6-cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine; Z499CLJ023; MFCD07784513; N~6~-Cyclohexyl-N~2~-(4-Morpholin-4-Ylphenyl)-9h-Purine-2,6-Diamine; N(6)-cyclohexyl-N(2)-[4-(morpholin-4-yl)phenyl]-9H-purine-2,6-diamine; 2vgo. CAS No. 656820-32-5. Molecular formula: C21H27N7O. Mole weight: 393.49. | |
| Reversine (2-(4-Morpholinoanilino)-6-cyclohexylaminopurine) | A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66uM) and an aurora kinase inhibitor (IC??'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 656820-32-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Revexepride | Revexepride, also referred as SSP-002358, is a very selective and potent 5-HT4 receptor agonist and a novel prokinetic that stimulates gastrointestinal motility, and could be a good candidate drug for the gastroparesis treatment. Synonyms: 4-amino-5-chloro-N-[[(3S,4S)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl]methyl]-2,2-dimethyl-3H-1-benzofuran-7-carboxamide; revexepride; SSP-002358; SSP 002358; SSP002358; Revexepride. Grades: >98%. CAS No. 219984-49-3. Molecular formula: C21H32ClN3O4. Mole weight: 425.95. | |
| Revumenib | Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding K i of 0.149 nM and a cell based IC 50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNDX-5613. CAS No. 2169919-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136175. | |
| Rexamino | Rexamino. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,5-Dihydro-4-phenyl-. Product Category: Heterocyclic Organic Compound. CAS No. 52883-35-9. Molecular formula: C9H10N2O. Mole weight: 162.19. Purity: 0.96. IUPACName: 4-phenyl-4,5-dihydro-1,3-oxazol-2-amine. Canonical SMILES: C1C(N=C(O1)N)C2=CC=CC=C2. Density: 1.264g/cm³. Product ID: ACM52883359. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Rezafungin | Rezafungin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-59-7. Molecular Formula: C63H85N8O17+. Mole Weight: 1226.41. Catalog: APB1396640597. |  |
| Rezafungin acetate | Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp. , Aspergillus spp. , and Pneumocystis spp. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Biafungin acetate; CD101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108009A. | |
| Rezafungin Impurity 1 | Rezafungin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396639-48-7. Molecular Formula: C63H85N8O17+. Mole Weight: 1226.41. Catalog: APB1396639487. | |
| Rezafungin Impurity 10 | Rezafungin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-25-7. Molecular Formula: C63H84FN8O17+. Mole Weight: 1244.4. Catalog: APB2649486257. | |
| Rezafungin Impurity 11 | Rezafungin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-80-4. Molecular Formula: C65H87N8O17+. Mole Weight: 1252.45. Catalog: APB2649486804. | |
| Rezafungin Impurity 12 | Rezafungin Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-31-5. Molecular Formula: C64H85N8O17+. Mole Weight: 1238.42. Catalog: APB2649486315. | |
| Rezafungin Impurity 13 | Rezafungin Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-14-4. Molecular Formula: C65H87N8O17+. Mole Weight: 1252.45. Catalog: APB2649486144. | |
| Rezafungin Impurity 14 | Rezafungin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-23-5. Molecular Formula: C66H89N8O17+. Mole Weight: 1266.48. Catalog: APB2649486235. | |
| Rezafungin Impurity 15 | Rezafungin Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-89-3. Molecular Formula: C63H82F3N8O17+. Mole Weight: 1280.38. Catalog: APB2649486893. | |
| Rezafungin Impurity 2 | Rezafungin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-55-3. Molecular Formula: C63H85N8O17+. Mole Weight: 1226.41. Catalog: APB1396640553. | |
| Rezafungin Impurity 3 | Rezafungin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2401852-82-0. Molecular Formula: C63H85N8O17+. Mole Weight: 1226.41. Catalog: APB2401852820. | |
| Rezafungin Impurity 4 | Rezafungin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-48-4. Molecular Formula: C64H87N8O17+. Mole Weight: 1240.44. Catalog: APB2649486484. | |
| Rezafungin Impurity 5 | Rezafungin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-50-8. Molecular Formula: C64H87N8O17+. Mole Weight: 1240.44. Catalog: APB2649486508. | |
| Rezafungin Impurity 6 | Rezafungin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649487-01-2. Molecular Formula: C64H87N8O17+. Mole Weight: 1240.44. Catalog: APB2649487012. | |
| Rezafungin Impurity 7 | Rezafungin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-11-1. Molecular Formula: C63H84FN8O17+. Mole Weight: 1244.4. Catalog: APB2649486111. | |
| Rezafungin Impurity 8 | Rezafungin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2649486-21-3. Molecular Formula: C64H85N8O17+. Mole Weight: 1238.42. Catalog: APB2649486213. | |
| Rezafungin Impurity 9 | Rezafungin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1672717-33-7. Molecular Formula: C63H86N9O17+. Mole Weight: 1241.43. Catalog: APB1672717337. | |
| Rezatapopt | Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PC14586. CAS No. 2636846-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156633. | |
| Rezatomidine | Rezatomidine is a selective α2-adrenoreceptor antagonist under the development of Allergan. No recent development was reported for the treatment of Diabetic neuropathies and Fibromyalgia. Synonyms: 2H-Imidazole-2-thione, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1,3-dihydro-; (S)-4-(1-(2,3-dimethylphenyl)ethyl)-1,3-dihydro-2H-imidazole-2-thione; 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydro-2H-imidazole-2-thione; (+)-(S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydroimidazole-2-thione. Grades: 98%. CAS No. 847829-38-3. Molecular formula: C13H16N2S. Mole weight: 232.35. | |
| Rezorstobart | Rezorstobart is an anti- KLRB1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2762201-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990760. | |
| Rezvilutamide | Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR3680. CAS No. 1572045-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137448. | |
| RF9 | RF9 is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382. | |
| RF 9 | RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grades: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62. | |
| RF9 (1-Adamantanecarbonyl-Arg-Phe-NH2) | Selective NPFF receptor antagonist (Ki values are 58 and 75nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo. Group: Biochemicals. Alternative Names: 1-Adamantanecarbonyl-Arg-Phe-NH2. Grades: Highly Purified. CAS No. 876310-60-0. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 482.62 free base. US Biological Life Sciences. | Worldwide |
| R-Fexofenadine (R-Carboxyterfenadine, R-Terfenadinecarboxyl ate) | A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: R-Carboxyterfenadine, R-Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| r-(-)-Flecainide | r-(-)-Flecainide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(2R)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (R)-Flecainide; (-)-Flecainide. Product Category: Heterocyclic Organic Compound. CAS No. 99495-90-6. Molecular formula: C17H20F6N2O3. Mole weight: 414.34. Product ID: ACM99495906. Alfa Chemistry ISO 9001:2015 Certified. | |
| R-(-)-Flecainide | R-(-)-Flecainide. Group: Biochemicals. Alternative Names: N-[ (2R) -2-Piperidinylmethyl]-2, 5-bis (2, 2, 2-trifluoroethoxy) benzamide; (R)-Flecainide; (-)-Flecainide. Grades: Highly Purified. CAS No. 99495-90-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H20F6N2O3. US Biological Life Sciences. | Worldwide |
| R-(-)-Flecainide | A stereoisomer of Flecainide. Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. Synonyms: N-[(2R)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (R)-Flecainide; (-)-Flecainide. Grades: > 95%. CAS No. 99495-90-6. Molecular formula: C17H20F6N2O3. Mole weight: 414.35. | |
| R-Flurbiprofen-acyl-β-D-glucuronide | R-Flurbiprofen-acyl-β-D-glucuronide is a metabolite of (R)-Flurbiprofen, the stereoisomer of Flurbiprofen. Synonyms: (R)Flurbiprofen-acyl-b-D-glucuronide. Grades: > 95%. CAS No. 162992-67-8. Molecular formula: C21H21F1O8. Mole weight: 420.39. | |
| R-Flurbiprofen Glucuronide | R-Flurbiprofen Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 162992-67-8. Molecular Formula: C21H21FO8. Mole Weight: 420.39. Catalog: APB162992678. | |
| RFP Expressing Glomerular Microvascular Endothelial Cells, Human (Frozen) | RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| RFP Expressing Glomerular Microvascular Endothelial Cells, Human (T-25 flask) | RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (Frozen) | Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (T-25 flask) | Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| RFP Expressing Retinal Microvascular Endothelial Cells, Human (Frozen) | Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| RFP Expressing Retinal Microvascular Endothelial Cells, Human (T-25 flask) | Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| RFP Expressing Saphenous Vein Endothelial Cells, Human (Frozen) | Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| RFP Expressing Saphenous Vein Endothelial Cells, Human (T-25 flask) | Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| RFP Expressing Umbilical Vein Endothelial Cells, Human (Frozen) | Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| RFP Expressing Umbilical Vein Endothelial Cells, Human (T-25 flask) | Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| R-Frovatriptan | . Uses: Tryptamines; carbazoles. Synonyms: (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide. Grades: > 95%. CAS No. 158747-02-5. Molecular formula: C14H19N3O. Mole weight: 243.33. | |
| RFRP-1 (human) | RFRP-1 (human), a mammalian ortholog of avian gonadotropin inhibitory hormone (GnIH), is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). RFRP-1 exhibits anorexigenic, anti-fertility, and anxiogenic activities. RFRP-1-secreting neurons are stress activated and inhibit the secretion of gonadotropin and gonadotropin-releasing hormone (GnRH). In vivo, this peptide inhibits reproductive behavior, decreases food intake, and increases anxiety behavior in an oxytocin-mediated manner. Synonyms: MPHSFANLPLRF; MPHSFANLPLRF-NH2. CAS No. 311309-25-8. Molecular formula: C67H101N19O14S. Mole weight: 1428.72. | |
| RFRP-1(human) | RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. | |
| RFRP 3 (human) | RFRP 3 (human). Group: Biochemicals. Grades: Purified. CAS No. 311309-27-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| RFRP 3 (human) | RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grades: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15. | |
| RFRP-3(human) | RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human). CAS No. 311309-27-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1250. | |
| RFRP3 (human) acetate | RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grades: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19. | |
| RG 102240 | RG 102240 is a stimulant, which induces a potent activator of gene expression. It does not cause significant changes in endogenous gene expression in HEK cells. Synonyms: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide; GS-E; GS-E (ligand); RSL 1; RheoSwitch Ligand 1; RheoSwitch Ligand RSL 1; RG-102240; RG 102240; RG102240. Grades: ≥98% by HPLC. CAS No. 162326-49-0. Molecular formula: C23H30N2O3. Mole weight: 382.5. | |
| RG108 | RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Synonyms: N-Phthalyl-L-tryptophan; RG-108; (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid. Grades: >98%. CAS No. 48208-26-0. Molecular formula: C19H14N2O4. Mole weight: 334.33. | |
| RG 108 | RG 108. Group: Biochemicals. Grades: Purified. CAS No. 48208-26-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RG 108 (N-Phthalyl-L-tryptophan) | A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. Group: Biochemicals. Grades: Highly Purified. CAS No. 48208-26-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RG13022 | RG13022, a non-phenolic tyrphostin analog, is an epidermal growth factor (EGF) receptor tyrosine kinase inhibitor with potential antiproliferative effect. Synonyms: RG13022; RG 13022; RG-13022; 3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile; RG 13022; RG-13022. CAS No. 136831-48-6. Molecular formula: C16H14N2O2. Mole weight: 266.29. | |
| RG14620 | RG14620 is a non-phenolic tyrphostin-class epidermal growth factor receptor (EGFR) inhibitor (IC50= 3 μM for HER 14 colony formation, and IC50= 1 pM for HER 14 DNA synthesis), with anti-proliferative effects on renal and bladder carcinoma cell lines. Synonyms: (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile; RG 14620; RG14620; RG-14620; TYRPHOSTIN RG 14620. CAS No. 136831-49-7. Molecular formula: C14H8Cl2N2. Mole weight: 275.13. | |
| RG2833 | RGFP 109 is a histone deacetylase (HDAC) inhibitor that has shown to reverse FXN gene silencing in short-term studies of Friedreich ataxia (FRDA) patient cells. Synonyms: RG-2833; RG 2833; RG2833; RGFP-109; RGFP 109; RGFP109.; N-[6-(2-Aminophenylamino)-6-oxohexyl]-4-methylbenzamide. Grades: >98%. CAS No. 1215493-56-3. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
| RG3039 | RG3039 is a potent DcpS inhibitor. It is used for the treatment for spinal muscular atrophy(SMA), which is caused by deletion or mutation of both copies of the SMN1 gene. It improves motor function in SMA mice. It also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models. It was developed by Repligen and now in Clinic Phase 1 with no progress. Uses: Rg3039 is used for the treatment for spinal muscular atrophy(sma). Synonyms: RG3039; RG 3039; RG-3039; PF06687859; PF 06687859; PF-06687859. 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine;5-[[1-[(2,6-dichlorophenyl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine. Grades: >98 %. CAS No. 1005504-62-0. Molecular formula: C21H23Cl2N5O. Mole weight: 432.35. | |
| RG-6080 | Nacubactam, also known as RG-6080, FPI-1459, and OP-0595, is a beta-lactamase inhibitor used for treating bacterial infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RG-6080; RG 6080; RG6080; FPI-1459; FPI 1459; FPI1459; OP-0595; OP 0595; OP0595; Nacubactam. Product Category: Inhibitors. Appearance: Off-white to beige solid powder. CAS No. 1452458-86-4. Molecular formula: C9H16N4O7S. Mole weight: 324.31. Purity: >98%. IUPACName: (1R,2S,5R)-2-((2-aminoethoxy)carbamoyl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Canonical SMILES: O=S(O)(ON1[C@]2([H])CC[C@@H](C(NOCCN)=O)[N@@](C2)C1=O)=O. Product ID: ACM1452458864. Alfa Chemistry ISO 9001:2015 Certified. | |
| RG7-0099 | RG7-0099 is a small-molecule and dual inhibitor of IDO1/TDO (IDO1 IC50 < 100nM while TDO IC50 < 100nM) , which modulate immunosuppressive effects. In preclinical models, it significantly reduced Kyn levels. RG7-0099 is potentially used in various cancers. Uses: Potential antitumor drug. Synonyms: RG7-0099; RG7 0099; RG70099. | |
| RG7090 | RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5). Synonyms: Basimglurant; CTEP Derivative; RG7090; RG 7090; RG-7090. Grades: >98%. CAS No. 802906-73-6. Molecular formula: C18H13ClFN3. Mole weight: 325.77. | |
| RG7129 | Cas No. 1628077-06-4. | |
| RG7800 | RG7800 is a selective Survival of motor neuron 1 protein (SMN1) stimulant and Survival of motor neuron 2 protein (SMN2) modulator originated by Roche. RG7800 shows excellent pharmacokinetic and in vivo efficacy and has a favorable safety profile. RG7800 can correct alternative splicing of the human. Phase I/II clinical trials for the treatment of Spinal muscular atrophyis on-going. Uses: Spinal muscular atrophy. Synonyms: RG7800; RG-7800; RG 7800; RO6885247; RO-6885247; RO 6885247. 2-(4-ethyl-6-methylpyrazolo[1,5-a]pyrazin-2-yl)-9-methyl-7-(1-methylpiperidin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: 98%. CAS No. 1449598-06-4. Molecular formula: C24H28N6O. Mole weight: 416.52. | |
| RG7834 | RG7834 is a highly selective and orally bioavailable HBV inhibitor, suppressing HBV antigens (both HBsAg and HBeAg) and virion production. Synonyms: RO 7020322; (6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydro-2h-pyrido[2,1-a]isoquinoline-3-carboxylic acid. Grades: ≥98% (HPLC). CAS No. 2072057-17-9. Molecular formula: C22H27NO6. Mole weight: 401.45. | |
| RGA-C11 | It is a mild glucoside detergent that can be used as an alternative to GDN, digitalin and CHAPS. Due to the formation of small protein-detergent complexes (PDCs) with GPCRs and their enhanced stability, this detergent is conducive to the determination of protein structures, particularly for CryoEM-based structural study. Synonyms: resorcinarene-based amphiphile-C11. Grades: >99%. CAS No. 2390023-16-0. Molecular formula: C132H216O56. Mole weight: 2699.09. | |
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