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| Product | Description | |
|---|---|---|
| Ro 08-2750 | Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM). NGF has potential effects on matrix turnover activity and influences the catabolic/anabolic balance of IVD cells in an adverse way that may potentiate IVD degeneration. Anti-NGF treatment might be beneficial to ameliorate progressive tissue breakdown in IVD degeneration and may lead to pain relief. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ro 08-2750; Ro08-2750; Ro-08-2750; Ro 082750; Ro -082750; Ro082750. Product Category: Inhibitors. Appearance: Orange to red solid powder. CAS No. 37854-59-4. Molecular formula: C13H10N4O3. Mole weight: 270.25. Purity: >95%. IUPACName: 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde. Canonical SMILES: O=CC1=C(C)C=C2N=C3C(NC(N=C3N(C)C2=C1)=O)=O. Product ID: ACM37854594. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ro 08-2750 | Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 ?M. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA[1]. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 ?M[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37854-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108466. |  |
| Ro 09-1679 | Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61. |  |
| Ro 10-5824 dihydrochloride | Ro 10-5824 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 189744-94-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Ro 106-9920 | Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Group: Biochemicals. Alternative Names: 6- (Phenylsulfinyl) tetrazolo[1, 5-b]pyridazine. Grades: Highly Purified. CAS No. 62645-28-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Ro106-9920 | A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties. Group: Fluorescence/luminescence spectroscopy. |  |
| Ro 11-1464 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO1138452 | RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAY10441. CAS No. 221529-58-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108912. | |
| Ro 1138452 hydrochloride | Ro 1138452 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 15-4513 | Ro 15-4513. Group: Biochemicals. Grades: Purified. CAS No. 91917-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 15-4513 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro15-4513 | Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) [1]. Ro15-4513 is a potent ethanol antagonist [2]. Ro15-4513 has anti-anxiety effect [3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 91917-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103476. | |
| Ro 19-4603 | Ro 19-4603. Group: Biochemicals. Grades: Purified. CAS No. 99632-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 20-1724 | Ro 20-1724. Group: Biochemicals. Grades: Purified. CAS No. 29925-17-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Ro 20-1724 | Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 20-174. CAS No. 29925-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100927. | |
| Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=2uM). Inhibits superoxide generation and arachidonic-induced platelet aggregation. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| RO 20-1724, cAMP-specific Phosphodiesterase Inhibitor (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| Ro-20-1724 - CAS 29925-17-5 | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 2 μM). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 23-9358 | ?97% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro24-7429 | Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 139339-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19149. | |
| Ro 25-6981 | Ro 25-6981 is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169274-78-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13993. | |
| Ro 25-6981 hydrochloride hydrate | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 25-6981 maleate | Potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Displays neuroprotectant effects in vivo and in vitro. Group: Biochemicals. Alternative Names: (αR, βS)-α-(4-Hydroxyphenyl)- β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate. Grades: Highly Purified. CAS No. 1312991-76-6. Pack Sizes: 1mg, 10mg, 50mg. Molecular Formula: C22H29NO2.C4H4O4, Molecular Weight: 455.55. US Biological Life Sciences. | Worldwide |
| Ro 25-6981 Maleate | Ro 25-6981 Maleate is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 Maleat shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 Maleate has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312991-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13993A. | |
| Ro 25-6981 maleate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 26-4550 trifluoroacetate | Ro 26-4550 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 1217448-66-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 27-3225 | Ro 27-3225 is a potent and selective melanocortin 4 receptor (MC4R) agonist. CAS No. 274682-89-2. Molecular formula: C39H52N12O6. Mole weight: 784.90. | |
| RO-3 | RO-3 is a potent, CNS-penetrant, and orally active P2X 3 and P2X 2/3 antagonist with pIC 50 s of 5.9 and 7.0 for human homomultimeric P2X 3 and heteromultimeric P2X 2/3 receptors, respectively. RO-3 shows selectivity for P2X 3 and P2X 2/3 over all other functional homomultimeric P2X receptors (IC 50 >10 μM at P2X 1,2,4,5,7 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1026582-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19978. | |
| RO-3 | RO-3. Group: Biochemicals. Grades: Purified. CAS No. 1026582-88-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 31-0432 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-7549, Monohydrate - CAS 125313-65-7 | A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC?? = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-8220 - CAS 138489-18-6 | A cell-permeable, reversible, competitive, and selective inhibitor of protein kinase C (PKC; IC?? = 10 nM) over CaM kinase II (IC?? = 17 μM) and protein kinase A (IC?? = 900 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 31-8220 mesylate | Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKC?, PKC?I, PKC?II, PKC?, PKC? and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3? (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. Ro 31-8220 mesylate can also inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, and these effects possess pharmacological properties independent of PKC[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate. CAS No. 138489-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13866. | |
| Ro 31-8220 mesylate | Ro 31-8220 mesylate. Group: Biochemicals. Grades: Purified. CAS No. 138489-18-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 31-8220 methanesulfonate salt | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-8425 - CAS 131848-97-0 | A potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor (IC?? = 15 nM for rat brain PKC). Group: Fluorescence/luminescence spectroscopy. | |
| RO3201195 | RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC 50 value of 190 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 249937-52-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-118612. | |
| Ro-32-0432 - CAS 145333-02-4 | A selective cell-permeable protein kinase C inhibitor. Group: Fluorescence/luminescence spectroscopy. | |
| RO3244794 | RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pK i of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 361457-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164580. | |
| Ro3280 | Ro3280 is a Polo-like kinase 1 (PLK1) inhibitor. Ro3280 shows strong antitumor activity in xenograft mouse models, has good selectivity against other kinases and has excellent in vitro cellular potency. Group: Biochemicals. Alternative Names: 4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide; 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide. Grades: Highly Purified. CAS No. 1062243-51-9. Pack Sizes: 5mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 543.61. US Biological Life Sciences. | Worldwide |
| RO3280 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 3306 | Ro 3306. Group: Biochemicals. Grades: Purified. CAS No. 872573-93-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro-3306 | Ro-3306 is a potent and selective inhibitor of CDK1, with Kis of 20 nM, 35 nM and 340 nM for CDK1, CDK1/cyclin B1 and CDK2/cyclin E, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 872573-93-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12529. | |
| RO-3306 | Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards. Group: Biochemicals. Alternative Names: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?OS?. US Biological Life Sciences. | Worldwide |
| RO-3306 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO-3306, CDK 1 Inhibitor ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one) | Cell-permeable. A selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Arrests cell cycle at G1, S, and G2/M and induces apoptosis in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines, and suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Group: Biochemicals. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Ro 363 hydrochloride | Ro 363 hydrochloride, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 250580-70-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123268A. | |
| Ro 41-0960 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 41-5253 | Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RAR?) antagonist. Ro 41-5253 can bind RAR? without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144092-31-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116248. | |
| Ro 41-5253 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro4368554 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 48-8071 fumarate | Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC 50 of appr 6.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 189197-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18630A. | |
| Ro 48-8071 fumarate | Ro 48-8071 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 189197-69-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RO4929097 | RO4929097 (RG-4733) is an orally active ? secretase inhibitor with an IC50 of 4 nM, inhibiting cellular processing of A?40 and Notch with EC50 of 14 nM and 5 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG-4733. CAS No. 847925-91-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11102. | |
| Ro 51 | Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3. P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a potential option in the treatment of pain. Group: Biochemicals. Alternative Names: 2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2-pyrimidinyl]amino]-1,3-propanediol; RO-51. Grades: Highly Purified. CAS No. 1050670-85-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RO5256390 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO5263397 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 5-3335 | Ro 5-3335. Group: Biochemicals. Grades: Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro5-3335 | Ro5-3335 Inhibitor. Uses: Scientific use. Product Category: T4687. CAS No. 30195-30-3. |  |
| Ro5-3335 | Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBF? interaction inhibitor that represses RUNX1/CBFB-dependent transactivation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30195-30-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108470. | |
| RO5454948 | Mirk-IN-1 (Dyrk1B/A-IN-1) is a highly efficient and selective inhibitor of Dyrk1B and Dyrk1A, with IC50 values of 68 and 22nM respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mirk-IN-1; Dyrk1B/A-IN-1. CAS No. 1386979-55-0. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12838. | |
| RO5 Drug-like Natural Product Library | 2743 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery. - Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more. - Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories. - Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives. Uses: Scientific use. Product Category: L6160. Categories: RO5 Drug-like Natural Product Libraries. | |
| Ro60-0175 | Ro60-0175 is a potent and selective agonist of 5-HT 2C receptor. Ro60-0175 reduces self-administration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-08-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123838. | |
| Ro 60-0175 fumarate | Ro 60-0175 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 169675-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro60-0175 fumarate | Ro60-0175 fumarate is a potent and selective agonist of 5-HT 2C receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-103140. | |
| Ro 61-8048 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 61-8048 | Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199666-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12347. | |
| Ro 61-8048 | Ro 61-8048. Group: Biochemicals. Grades: Purified. CAS No. 199666-03-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 64-5229 | Ro 64-5229. Group: Biochemicals. Grades: Purified. CAS No. 246852-46-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 64-6198 | Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC 50 value of 25.6 nM. Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors. Ro 64-6198 can be used for stress and anxiety, addiction, neuropathic pain, cough, and anorexia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280783-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-12844. | |
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