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| Product | Description | |
|---|---|---|
| Rimegepant Impurity 12 | Rimegepant Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1397526-07-6. Molecular formula: C25H33F2NO2Si. Mole weight: 445.63. Catalog: APB1397526076. |  |
| Rimegepant Impurity 7 | Rimegepant Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1397526-04-3. Molecular formula: C10H13NO2. Mole weight: 179.22. Catalog: APB1397526043. | |
| Rimegepant Impurity 9 | Rimegepant Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1397526-01-0. Molecular formula: C10H11NO2. Mole weight: 177.2. Catalog: APB1397526010. | |
| Rimeporide | Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na + /H + exchanger (NHE-1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD-87580. CAS No. 187870-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19273. |  |
| Rimeporide-15N3 Hydrochloride | Rimeporide-15N3 Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide-15N3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C11H16Cl15N3O5S2, Molecular Weight: 372.83. US Biological Life Sciences. |  Worldwide |
| Rimeporide Hydrochloride | Rimeporide Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide Hydrochloride. Grades: Highly Purified. CAS No. 187870-95-7. Pack Sizes: 10mg. Molecular Formula: C11H16ClN3O5S2, Molecular Weight: 369.84. US Biological Life Sciences. | Worldwide |
| Rimexolone | Rimexolone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Asoprisnil ecamate; (8S,9S,10R,11S,13S,14S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propionyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. Product Category: Steroidal Compounds. CAS No. 49697-38-3. Molecular formula: C24H34O3. Mole weight: 370.53. Purity: 95%+. IUPACName: Rimexolone. Density: 1.12. Product ID: ACM49697383. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Rimexolone | Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye for the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis. Uses: Anti-inflammatory. Synonyms: Trimexolone; Org 6216; Org6216; Org-6216; 11β-Hydroxy-16α,17α,21-trimethylpregna-1,4-dien-3,20-dione. Grades: ≥98%. CAS No. 49697-38-3. Molecular formula: C24H34O3. Mole weight: 370.52. |  |
| Rimiducid | Rimiducid (AP1903) is a dimerizer agent that acts by cross-linking the FKBP domains. Rimiducid (AP1903) dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP1903. CAS No. 195514-63-7. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16046. | |
| Rimiterol | 1-(1,2-Benzoxazol-3-yl)methanesulphonamide, Zonisamide. β2-agonist. CAS No. 32953-89-2. Product ID: 2-08327. Molecular formula: C12H17NO3. Mole weight: 223.27. |  |
| Rimiterol Hydrobromide | 4-{(S)-hydroxy[(2 R)-piperidin-2-yl]methyl}benzene-1,2-diol HBr. anti-migraine therapeutic. CAS No. 113383-53-2. Product ID: 2-08326. Molecular formula: C12H18BrNO3. Mole weight: 304.18. | |
| Rimocidin | It is originally isolated from Str. rimosus and it has antifungal and protozoan effects. Synonyms: Rimocidine. Grades: >98%. CAS No. 1393-12-0. Molecular formula: C39H61NO14. Mole weight: 767.90. | |
| Rimonabant | Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a K i of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR141716. CAS No. 168273-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14136. | |
| Rimonabant | 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide. CAS No. 158681-13-1. Product ID: 2-08289. Molecular formula: C22H21N4OCl3. Mole weight: 463.79. | |
| Rimonabant | Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Synonyms: SR141716; SR 141716; SR-141716. Grades: >98%. CAS No. 168273-06-1. Molecular formula: C22H21Cl3N4O. Mole weight: 463.79. | |
| Rimonabant Hydrochloride | The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists. Group: Biochemicals. Alternative Names: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide hydrochloride. Grades: Highly Purified. CAS No. 158681-13-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Rimonabant Hydrochloride | Rimonabant Hydrochloride, used as a tool to investigate CB receptor properties, it is a selective antagonist of cannabinoid CB1 receptor (Ki = 1.98 nM) and inverses adenylyl cyclase inhibition (IC50 = 48 nM). Uses: A brain cannabinoid receptor (cb1) antagonist. antiobesity agent. Synonyms: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; Rimonabant free base, SR141716; SR 141716; SR-141716; A 281; A-281; A281; Rimonabant, Acomplia, Zimulti. Grades: 98%. CAS No. 158681-13-1. Molecular formula: C22H21Cl3N4O.HCl. Mole weight: 500.25. | |
| Rimonabant Hydrochloride | Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an K i of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 141716A Hydrochloride. CAS No. 158681-13-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14137. | |
| R-IMPP | R-IMPP is an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a regulator of low-density lipoprotein cholesterol (LDL-C), which is related to the risk of atherosclerosis and other cardiovascular disorders. Uses: An inhibitor of proprotein convertase subtilisin/kexin type 9 (pcsk9). Synonyms: RIMPP; R IMPP; (R)-IMPP; (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide. CAS No. 2133832-83-2. Molecular formula: C24H27N3O2. Mole weight: 389.50. | |
| R-IMPP hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Rimsulfuron | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. | |
| Rimsulfuron | Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide for postemergence use in maize to control grasses and some broadleaf weeds [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPX-E9636. CAS No. 122931-48-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-133085. | |
| Rimsulfuron | Rimsulfuron. Group: Biochemicals. Grades: Highly Purified. CAS No. 122931-48-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Rinatabart | HY-P990941 is an FOLR1 -targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2853518-94-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990941. | |
| R)-(+)-Indoline-2-carboxylic acid | 5g Pack Size. Group: Building Blocks, Chiral Compounds, Indoles, Organics. Formula: C9H9NO2. CAS No. 98167-06-7. Prepack ID 56971128-5g. Molecular Weight 163.17. See USA prepack pricing. |  |
| R-Indoxacarb | the R-enantiomer of Indoxacarb. Synonyms: (4aR) -7-Chloro-2, 5-dihydro-2-[[ (methoxycarbonyl) [4- (trifluoromethoxy) phenyl]amino]carbonyl]-indeno[1, 2-e][1, 3, 4]oxadiazine-4a (3H) -carboxylic Acid Methyl Ester; (R) -7-Chloro-2, 5-dihydro-2-[[ (methoxycarbonyl) [4- (trifluoromethoxy) phenyl]amino]carbonyl]-inde. Grades: > 95%. CAS No. 185608-75-7. Molecular formula: C22H17F3N3O7. Mole weight: 527.84. | |
| Rineterkib | Rineterkib is a RAF and ERK1/2 inhibitor developed for the treatment of proliferative diseases characterized by activating mutations in the MAPK pathway. Synonyms: ERK-IN-1; LTT-462. CAS No. 1715025-32-3. Molecular formula: C26H27BrF3N5O2. Mole weight: 578.4. | |
| Rineterkib free base | Rineterkib, also known as LTT-462 or ERK-IN-1, is a ERK1/2 inhibitor which has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models. LTT462 binds to and inhibits ERK, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in numerous tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Rineterkib; ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1; LTT 462; LTT-462; LTT462. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1715025-32-3. Molecular formula: C26H27BrF3N5O2. Mole weight: 578.43. Purity: >98%. IUPACName: 4-{3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl]-2-fluorobenzamide. Canonical SMILES: O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F. Product ID: ACM1715025323. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ringer Solution, Amphibian, Laboratory Grade, 1 L | Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. Product ID: 886503. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| RING-type E3 ubiquitin transferase | The RING domain of E3 ubiquitin transferase serves as a mediator bringing the ubiquitin-charged E2 ubiquitin-conjugating enzyme and the acceptor protein together to enable the direct transfer of ubiquitin through the formation of an isopeptide bond between the C-terminal glycine residue of ubiquitin an the ε-amino group of an L-lysine residue of the acceptor protein. The RING-E3 domain does not form a catalytic thioester intermediate with ubiquitin (unlike the HECT domain, EC 2.3.2.26). RING-type ubiquitin transferases may occur as single-chain enzymes but also in dimeric forms or in multi-subunit assemblies. Group: Enzymes. Synonyms: RING E3 ligase (misleading); ubiquitin transferase RING E3. Enzyme Commission Number: EC 2.3.2.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2301; RING-type E3 ubiquitin transferase; EC 2.3.2.27; RING E3 ligase (misleading); ubiquitin transferase RING E3. Cat No: EXWM-2301. |  |
| Rink amide (aminomethyl)polystyrene (1 % cross-linked) | Rink amide (aminomethyl)polystyrene (1 % cross-linked). Group: Polystyrene (ps). |  |
| Rink amide (aminomethyl)polystyrene (extent of labeling: ~1.1mmol/g loading) | Rink amide (aminomethyl)polystyrene (extent of labeling: ~1.1mmol/g loading). Group: Polystyrene (ps). | |
| Rink amide AM resin | Rink amide AM resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Rink amide AM resin (with Nle) | Rink amide AM resin (with Nle). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink Amide Linker | Rink amide linker requires concentrated TFA for complete peptide cleavage from the resin. Synonyms: Fmoc-NH-SAL Resin Linker; Rink Amide Reagent; 4-[(R,S)-α-{1-(9H-Fluoren-9-yl)methoxyformamido}-2,4-dimethoxybenzyl]phenoxyacetic acid. CAS No. 126828-35-1. Molecular formula: C32H29NO7. Mole weight: 539.56. | |
| Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)phenoxyacetic acid | 1g Pack Size. Group: Building Blocks, Organics, Peptide Reagents. Formula: C32H29NO7. CAS No. 145069-56-3. Prepack ID 72830185-1g. Molecular Weight 539.58. See USA prepack pricing. | |
| Rink amide MBHA resin, | Rink amide MBHA resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink amide MBHA resin (with Norleucine) | Rink amide MBHA resin (with Norleucine). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink amide PEGA resin | Rink amide PEGA resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Rink amide resin | Rink amide resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Rintodestrant | Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: G1T48. CAS No. 2088518-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137449. | |
| Rinvanil | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Riociguat | Riocguat is used in the treatment for pulmonary hypertension. Group: Biochemicals. Alternative Names: N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamic Acid Methyl Ester; [4, 6-Diamino-2- [1- [ (2-fluorophenyl) methyl] -1H-pyrazolo [3, 4-b] pyridin-3-yl] -5-pyrimidinyl] methylcarbamic Acid Methyl Ester; BAY 63-2521; BAY 632521; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate. Grades: Highly Purified. CAS No. 625115-55-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Riociguat | Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators. Synonyms: BAY 63-2521; BAY63-2521; BAY632521; Riociguat; Brand name: Adempas. Grades: 0.99. CAS No. 625115-55-1. Molecular formula: C20H19FN8O2. Mole weight: 422.424. | |
| Riociguat | Riociguat is an oral stimulator of soluble guanylate cyclase ( sGC ) used in the treatment of pulmonary hypertension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 632521. CAS No. 625115-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14779. | |
| Riociguat Impurity 1 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)(methyl)carbamate; Riociguat Impurity I. Grades: > 95%. Molecular formula: C21H21FN8O2. Mole weight: 436.45. | |
| Riociguat Impurity 2 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidic acid methyl ester. Grades: > 95%. CAS No. 304874-06-4. Molecular formula: C15H13FN4O. Mole weight: 284.3. | |
| Riociguat Impurity 3 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Grades: > 95%. Molecular formula: C23H20FN9. Mole weight: 441.47. | |
| Riociguat Impurity 4 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Dimethyl (6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5-diyl)dicarbamate. Grades: > 95%. Molecular formula: C21H19FN8O4. Mole weight: 466.44. | |
| Riociguat Impurity 5 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)carbamate. Grades: > 95%. Molecular formula: C20H19FN8O2. Mole weight: 422.43. | |
| Riociguat Impurity 6 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-N5-methyl-4,5,6-pyrimidinetriamine. Grades: > 95%. CAS No. 1702271-98-4. Molecular formula: C18H17FN8. Mole weight: 364.39. | |
| Riociguat Impurity 7 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-((methoxycarbonyl)amino)pyrimidin-5-yl)(methyl)carbamate. Grades: > 95%. Molecular formula: C22H21FN8O4. Mole weight: 480.46. | |
| Riociguat Impurity 7 | Riociguat Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1702271-98-4. Molecular formula: C18H17FN8. Mole weight: 364.39. Catalog: APB1702271984. | |
| Riociguat M1 Glucuronide | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Grades: > 95%. Molecular formula: C25H25FN8O8. Mole weight: 584.53. | |
| Riodoxol (2,4,6-Triiodoresorcinol) | A iodinated derivative of Resorcinol, a benzene derivative used as keratolytic and antiseborrheic. Also used in veterinary medicine as a topical antipruritic and antiseptic. Synonyms: 2,4,6-Triiodoresorcinol. Grades: > 95%. CAS No. 19403-92-0. Molecular formula: C6H3I3O2. Mole weight: 487.8. | |
| RIPA-56 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RIPA-56 | RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) (IC50 = 13 nM), and efficiently reduced tumor necrosis factor alpha (TNFα)-induced mortality and multiorgan damage. Synonyms: RIPA-56; RIPA-56; RIPA-56. N-benzyl-N-hydroxy-2,2-dimethylbutanamide. CAS No. 1956370-21-0. Molecular formula: C13H19NO2. Mole weight: 221.3. | |
| RIPA Lysis Buffer | RIPA lysis buffer is used to lyse cultured cells for immunoprecipitation and immunoblots. Similar in function to single detergent buffers that include NP-40, sodium chloride and Tris, RIPA is a good first choice for new antigens. Group: Biochemicals. Alternative Names: 150mM NaCl, 1.0% NP-40, 0.5% deoxycholate, 0.1% SDS, 50mM Tris-Cl. Grades: Molecular Biology Grade. Pack Sizes: 10ml, 25ml, 50ml, 100ml. US Biological Life Sciences. | Worldwide |
| Riparin-2.1 | Riparin-2.1 is an antibacterial peptide isolated from Crinia riparia. It is a narrow-spectrum antibiotic with an MIC of 25 μM against Lactococcus lactis. Synonyms: Ile-Ile-Glu-Lys-Leu-Val-Asn-Thr-Ala-Leu-Gly-Leu-Leu-Ser-Gly-Leu-NH2. Grades: >96%. Molecular formula: C76H137N19O21. Mole weight: 1653.04. | |
| Ripasudil | Ripasudil (K-115) is a specific inhibitor of ROCK , with IC 50 s of 19 and 51 nM for ROCK2 and ROCK1 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-115. CAS No. 887375-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15685. | |
| Ripasudil (K-115) | Ripasudil is a potent ROCK inhibitor with IC50 values of 51 nM and 19 nM for ROCK1 and ROCK2, respectively. It has been used in eye drops for the treatment of corneal endothelial injuries. Synonyms: K-115; 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrate hydrochloride. Grades: >98%. CAS No. 887375-67-9. Molecular formula: C15H23ClFN3O4S. Mole weight: 395.88. | |
| RIPK1-IN-19 | RIPK1-IN-19 (compound 10b) is a selective RIPK1 inhibitor ( IC 50 =15 nM). RIPK1-IN-19 displays potent protective activity in TNFα-induced systemic inflammatory response syndrome (SIRS) model and Imiquimod (IMQ)-induced psoriasis model. RIPK1-IN-19 can be used in research on inflammation and immune system diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763831-43-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157456. | |
| RIPK2 (1-299), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| RIPK3, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| RIPK5, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Ripple | Ripple. Group: Polymers. | |
| Ripretinib | Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2) [1] [2]. DCC-2618 exerts antineoplastic effect and induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCC-2618. CAS No. 1442472-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112306. | |
| Ripretinib | Ripretinib is an orally bioavailable KIT/PDGFR inhibitor with antitumor effect. It binds to both wild-type and mutant forms of KIT and PDGFRa at their switch pocket binding site. Synonyms: DCC-2618; 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea. CAS No. 1442472-39-0. Molecular formula: C24H21BrFN5O2. Mole weight: 510.36. | |
| Ripromycin | Ripromycin is produced by the strain of Streptomyces sp Tu 6239. It has moderate anti-gram-positive bacterial activity, but not anti-gram-negative bacteria or fungi. It inhibited the proliferation of HM02 and MCF cells with IC50 of 1.6 and 2.0 μg/mL, respectively. Molecular formula: C30H40N2O6. Mole weight: 524.65. | |
| Risankizumab | Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting IL-23 p19 subunit ( K d <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC 50 = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Risankizumab rzaa; BI 655066. CAS No. 1612838-76-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99248. | |
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