A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Rubitecan | Rubitecan. Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3', 4':6, 7]indolizinol[1, 2-b]quinoline-3, 14(4H, -12H)-dione; 9-Nitrocamptothecin; 9-NC. Grades: Highly Purified. CAS No. 91421-42-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H15N3O6. US Biological Life Sciences. |  Worldwide |
| Rubitecan ((4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3, 4:6, 7]indolizinol[1, 2-b]quinoline-3, . 14(4H,-12H)-dione, 9-Nitrocamptothecin, 9-NC, Orathecin) | Semisynthetic camptothecin which inhibits DNA topoisomerase I. Prodrug of 9-aminocamptothecin. Antineoplastic. Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3, 4:6, 7]indolizinol[1, 2-b]quinoline-3, 14(4H, -12H)-dione; 9-Nitrocamptothecin; 9-NC; Orathecin. Grades: Highly Purified. CAS No. 91421-42-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rubixanthin | Rubixanthin. Group: Biochemicals. Grades: Highly Purified. CAS No. 3763-55-1. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C40H56O. US Biological Life Sciences. | Worldwide |
| Rubiyunnanin C | Other Alkaloids. CAS No. 1261030-04-9. Mole weight: 828.9. Purity: 95%+. Catalog: ACM1261030049. |  |
| Ruboxistaurin | Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531. CAS No. 169939-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195. |  |
| Ruboxistaurin | Ruboxistaurin, also called as LY 333531, initially developed for the treatment of diabetic retinopathy, inhibits isolated enzymes PKCβI and PKCβII with a half-maximal inhibitory constant of 4.5 and 5.9 nM, respectively. The half-life of ruboxistaurin, which can be orally administered, is approximately 9h and that of its metabolite 16h, therefore allowing once-daily dosing. Based on data from clinicalTrials.gov, Children's Hospital Medical Center, Cincinnati plan a phase I/II trial of the effect of ruboxistaurin for its safety, tolerability, and effectiveness in treating adult patients with heart failure on June 9, 2016. Synonyms: 13-((dimethylamino)methyl)-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H,13H-dibenzo(e,k)pyrrolo(3,4-h)(1,4,13)oxadiazacyclohexadecene-1,3(2H)-dione; Arxxant; LY 333531; LY-333531; LY333531; ruboxistaurin; ruboxistaurin mesilate hydrate. CAS No. 169939-94-0. Molecular formula: C28H28N4O3. Mole weight: 468.557. |  |
| Ruboxistaurin HCl | Ruboxistaurin, also called as LY 333531, initially developed for the treatment of diabetic retinopathy, inhibits isolated enzymes PKCβI and PKCβII with a half-maximal inhibitory constant of 4.5 and 5.9 nM, respectively. The half-life of ruboxistaurin, which can be orally administered, is approximately 9h and that of its metabolite 16h, therefore allowing once-daily dosing. Based on data from clinicalTrials.gov, Children's Hospital Medical Center, Cincinnati plan a phase I/II trial of the effect of ruboxistaurin for its safety, tolerability, and effectiveness in treating adult patients with heart failure on June 9, 2016. Uses: Enzyme inhibitors. Synonyms: Ruboxistaurin Hydrochloride; LY-333531 hydrochloride; Ruboxistaurin (hydrochloride); 169939-93-9; LY 333531 hydrochloride; LY333531 hydrochloride; Ruboxistaurin-d6 Hydrochloride; 169939-94-0 (base). Grades: > 95%. CAS No. 169939-93-9. Molecular formula: C28H28N4O3.HCl. Mole weight: 505.01. | |
| Ruboxistaurin hydrochloride | Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 hydrochloride. CAS No. 169939-93-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195B. | |
| Ruboxistaurin hydrochloride | Ruboxistaurin hydrochloride. Group: Biochemicals. Alternative Names: (9S) -9-[ (Di methyl amino) methyl ]-6, 7, 10, 11-tetra hydro-9H, 18H-5, 21: 12, 17-dimethenodibenzo [e, k ] pyrrolo [3, 4-h] [1, 4, 13] oxadiaz acyclohexadecine-18, 20 (19H) -dione hydrochloride; LY 333531. Grades: Highly Purified. CAS No. 169939-93-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H29ClN4O3. US Biological Life Sciences. | Worldwide |
| Ruboxistaurin mesylate | Ruboxistaurin (LY333531) mesylate is an orally active, selective and ATP competitive PKCβ inhibitor with IC 50 values of 4.7 and 5.9 nM for PKCβI and PKCβII, respectively. Ruboxistaurin mesylate can be used for the research of eye disorders, heart failure and diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 mesylate. CAS No. 192050-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10195A. | |
| Ru(bpm)3(PF6)2 | . Uses: Transition metal catalysts. Synonyms: Tris(2,2-bipyrimidine) Ruthenium dihexafluorophosphate; Ruthenium(2+), tris(2,2'-bipyrimidine-κN1,κN1')-, (OC-6-11)-, hexafluorophosphate(1-) (1:2); 2,2'-Bipyrimidine, ruthenium complex; Phosphate(1-), hexafluoro-, (OC-6-11)-tris(2,2'-bipyrimidine-N1,N1')ruthenium(2+) (2:1); Ruthenium(2+), tris(2,2'-bipyrimidine-N1,N1')-, (OC-6-11)-, bis[hexafluorophosphate(1-)]; Ruthenium(2+), tris(2,2'-bipyrimidine-κN1,κN1')-, (OC-6-11)-, bis[hexafluorophosphate(1-)]. Grades: ≥95%. CAS No. 85335-55-3. Molecular formula: C24H18N12Ru.2F6P. Mole weight: 865.48. | |
| Ru(bpy)2(bpm)(BF4)2 | . Uses: Transition metal catalysts. Synonyms: Ruthenium(2+), bis(2,2'-bipyridine-κN1,κN1')(2,2'-bipyrimidine-κN1,κN1')-, (OC-6-22)-, tetrafluoroborate(1-) (1:2); Bis(2,2'-bipyridyl)(2,2'-bipyrimidine)ruthenium tetrafluoroborate. Grades: ≥95%. CAS No. 1254690-00-0. Molecular formula: C28H22N8Ru.2BF4. Mole weight: 745.20. | |
| Ru(bpy)2(bpm)(BF4)2 | Ruthenium Photosensitizers. Alternative Names: Bis(2, 2'-bipyridyl)(2, 2'-bipyrimidine)ruthenium tetrafluoroborate. CAS No. 1254690-00-0. Molecular formula: C28H22B2F8N8Ru. Mole weight: 745.22. Appearance: Powder. Purity: 0.95. Catalog: ACM1254690000. | |
| Ru(bpz)3(Cl)2 | . Uses: Transition metal catalysts. Synonyms: Tris(2,2'-bipyrazine) Ruthenium dihydrochloride; Ruthenium(2+), tris(2,2'-bipyrazine-κN1,κN1')-, chloride (1:2), (OC-6-11)-; 2,2'-Bipyrazine, ruthenium complex; Ruthenium(2+), tris(2,2'-bipyrazine-N1,N1')-, dichloride, (OC-6-11)-; Ruthenium(2+), tris(2,2'-bipyrazine-κN1,κN1')-, dichloride, (OC-6-11)-; Tris(2,2'-bipyrazine)ruthenium(2+) dichloride; Tris(bipyrazine)ruthenium(2+) dichloride. Grades: ≥95%. CAS No. 80925-50-4. Molecular formula: C24H18N12Ru.2Cl. Mole weight: 646.45. | |
| Rubradirin B | Rubradirin B is produced by the strain of Str. achromogenes var. rubradiris. It has the effect of anti-gram-positive bacteria. Grades: >98%. CAS No. 68833-11-4. Molecular formula: C40H33N3O15. Mole weight: 795.70. | |
| Rubratoxin A | Rubratoxin A is a competitive inhibitor of protein phosphatase 2A (PP2A) with anticancer activity. It hardly inhibits any other phosphatases. Rubratoxin A showed higher suppression of tumor metastasis and reduction of the primary tumor volume than cytostatin in mouse experiments. Synonyms: BRN 1633008; HSDB 3532. Grades: ≥95%. CAS No. 22467-31-8. Molecular formula: C26H32O11. Mole weight: 520.5. | |
| Rubratoxin A | Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic. Group: Biochemicals. Alternative Names: BRN 1633008; HSDB 3532, (4S,5R,10R)-rel-10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione. Grades: Highly Purified. CAS No. 22467-31-8. Pack Sizes: 250ug, 500ug. Molecular Formula: C??H??O??. US Biological Life Sciences. | Worldwide |
| Rubratoxin B | Rubratoxin B is a mycotoxin that causes hypoglycemia and fatty liver, and has anti-cancer activity. Synonyms: J38U4758MY. Grades: 98%. CAS No. 21794-01-4. Molecular formula: C26H30O11. Mole weight: 518.5. | |
| rubredoxin-NAD(P)+ reductase | The enzyme from Pyrococcus furiosus requires FAD. It reduces a number of electron carriers, including benzyl viologen, menadione and 2,6-dichloroindophenol, but rubredoxin is the most efficient. Ferredoxin is not utilized. Group: Enzymes. Synonyms: rubredoxin-nicotinamide adenine dinucleotide (phosphate) reductase; rubredoxin-nicotinamide adenine; dinucleotide phosphate reductase; NAD(P)+-rubredoxin oxidoreductase; NAD(P)H-rubredoxin oxidoreductase. Enzyme Commission Number: EC 1.18.1.4. CAS No. 80237-97-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1109; rubredoxin-NAD(P)+ reductase; EC 1.18.1.4; 80237-97-4; rubredoxin-nicotinamide adenine dinucleotide (phosphate) reductase; rubredoxin-nicotinamide adenine; dinucleotide phosphate reductase; NAD(P)+-rubredoxin oxidoreductase; NAD(P)H-rubredoxin oxidoreductase. Cat No: EXWM-1109. |  |
| rubredoxin-NAD+ reductase | Requires FAD. The enzyme from Clostridium acetobutylicum reduces rubredoxin, ferricyanide and dichlorophenolindophenol, but not ferredoxin or flavodoxin. The reaction does not occur when NADPH is substituted for NADH. Contains iron at the redox centre. Group: Enzymes. Synonyms: rubredoxin reductase; rubredoxin-nicotinamide adenine dinucleotide reductase; dihydronicotinamide adenine dinucleotide-rubredoxin reductase; reduced nicotinamide adenine dinucleotide-rubredoxin reductase; NADH-rubredoxin reductase; rubredoxin-NAD reductase; NADH: rubredoxin oxidoreductase; DPNH-rubredoxin reductase; NADH-rubredoxin oxidoreductase. Enzyme Commission Number: EC 1.18.1.1. CAS No. 9032-27-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1106; rubredoxin-NAD+ reductase; EC 1.18.1.1; 9032-27-3; rubredoxin reductase; rubredoxin-nicotinamide adenine dinucleotide reductase; dihydronicotinamide adenine dinucleotide-rubredoxin reductase; reduced nicotinamide adenine dinucleotide-rubredoxin reductase; NADH-rubredoxin reductase; rubredoxin-NAD reductase; NADH: rubredoxin oxidoreductase; DPNH-rubredoxin reductase; NADH-rubredoxin oxidoreductase. Cat No: EXWM-1106. | |
| Rubrene | TGA/DSC Lot specific traces available upon request. Uses: Organic electronic material useful as oled dopant (red, λem = 550nm) and as p-type organic semiconductor. carrier mobilities of 8-20 cm2 / vs can be achieved in ofets based on single crystals of sublimed rubrene. Group: Bioelectronic materials organic field effect transistor (ofet) materials organic light-emitting diode (oled) materials sublimed materials other materials. Alternative Names: 5,6,11,12-Tetraphenylnaphthacene. CAS No. 517-51-1. Pack Sizes: 1, 5 g in glass bottle. Product ID: 5,6,11,12-tetraphenyltetracene. Molecular formula: 532.67. Mole weight: C42H28. C1=CC=C (C=C1) C2=C3C=CC=CC3=C (C4=C (C5=CC=CC=C5C (=C24) C6=CC=CC=C6) C7=CC=CC=C7) C8=CC=CC=C8. InChI=1S/C42H28/c1-5-17-29 (18-6-1) 37-33-25-13-14-26-34 (33) 39 (31-21-9-3-10-22-31) 42-40 (32-23-11-4-12-24-32) 36-28-16-15-27-35 (36) 38 (41 (37) 42) 30-19-7-2-8-20-30/h1-28H. YYMBJDOZVAITBP-UHFFFAOYSA-N. 95%+. |  |
| Rubrene | TGA/DSC Lot specific traces available upon request. Uses: Organic electronic material useful as oled dopant (red, λem = 550nm) and as p-type organic semiconductor. carrier mobilities of 8-20 cm2 / vs can be achieved in ofets based on single crystals of sublimed rubrene. Group: Organic light emitting diode (oled). Alternative Names: 5,6,11,12-Tetraphenylnaphthacene. CAS No. 517-51-1. Molecular formula: C42H28. Mole weight: 532.67 g/mol. Purity: 95%+. IUPACName: 5,6,11,12-tetraphenyltetracene. Canonical SMILES: C1=CC=C (C=C1) C2=C3C=CC=CC3=C (C4=C (C5=CC=CC=C5C (=C24) C6=CC=CC=C6) C7=CC=CC=C7) C8=CC=CC=C8. ECNumber: 208-242-0. Catalog: ACM517511. | |
| Rubrene, 99%, purified by sublimation | Rubrene, 99%, purified by sublimation. Group: other materials. CAS No. 517-51-1. Product ID: 5,6,11,12-tetraphenyltetracene. Molecular formula: 532.7g/mol. Mole weight: C42H28. C1=CC=C (C=C1) C2=C3C=CC=CC3=C (C4=C (C5=CC=CC=C5C (=C24) C6=CC=CC=C6) C7=CC=CC=C7) C8=CC=CC=C8. InChI=1S/C42H28/c1-5-17-29 (18-6-1) 37-33-25-13-14-26-34 (33) 39 (31-21-9-3-10-22-31) 42-40 (32-23-11-4-12-24-32) 36-28-16-15-27-35 (36) 38 (41 (37) 42) 30-19-7-2-8-20-30/h1-28H. YYMBJDOZVAITBP-UHFFFAOYSA-N. | |
| Rubrofusarin (NSC 258316) | Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 3567-00-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rubromycin Beta (Methyl-8,10'-dihydroxy-5,7-dimethoxy-4,9,9'-trioxo-4,4',9,9'-tetrahydro-3H,3'H-spiro[naphtho[2,3-b]furan-2,2'-pyrano[4,3-g]chromene]-7'-carboxylate) | Antibiotic. HIV-1 reverse transcriptase inhibitor. Human telomerase inhibitor. Cytostatic against different tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 27267-70-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rubromycin Gamma | Antibiotic. HIV-1 reverse transcriptase and human telomerase inhibitor. Antibacterial. Cytostatically active against different tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 27267-71-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rubropunctamine | A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, [R-(E)]-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-, (9aR)- (9CI). Grades: > 95%. CAS No. 514-66-9. Molecular formula: C21H23NO4. Mole weight: 353.42. | |
| Rubropunctatin | A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(9aH)?-dione, 9a-methyl-3-(1-oxohexyl)?-6-(1E)?-1-propen-1-yl-, (9aR)?-. Grades: > 95%. CAS No. 514-67-0. Molecular formula: C21H22O5. Mole weight: 354.41. | |
| Rubusoside | Rubusoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 64849-39-4. Pack Sizes: 20mg. Molecular Formula: C32H50O13, Molecular Weight: 642.73. US Biological Life Sciences. | Worldwide |
| RUBUSOSIDE | RUBUSOSIDE. CAS No. 64849-39-4. Pack Sizes: 1 kg. Product ID: CDC10-0550. Molecular formula: C32H50O13. Category: Cosmetic Sweeteners. Product Keywords: Cosmetic Ingredients; Cosmetic Sweeteners; RUBUSOSIDE; CDC10-0550; 64849-39-4; C32H50O13; 64849-39-4. Purity: 0.99. Color: White to Off-White. Physical State: Neat. Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly). Storage: Hygroscopic, Refrigerator, under inert atmosphere. Boiling Point: 802.5±65.0 °C(Predicted). Melting Point: 178~181°C. |  |
| Ruby Powder | Ruby Powder. Group: other nano materials. CAS No. 12174-49-1. Mole weight: Al2O3 : Cr3+. 99.9%. | |
| Ruby Powder | Other Nanomaterials. CAS No. 12174-49-1. Molecular formula: Al2O3 : Cr3+. Purity: 0.999. Density: 3.97g/cm³. Catalog: ACM12174491. | |
| Ruby sphere; diameter(mm), 0.25; grade 25 | Ruby sphere; diameter(mm), 0.25; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 0.50; grade 25 | Ruby sphere; diameter(mm), 0.50; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 0.75; grade 25 | Ruby sphere; diameter(mm), 0.75; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.00; grade 25 | Ruby sphere; diameter(mm), 1.00; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.19 (3/64 in); grade 25 | Ruby sphere; diameter(mm), 1.19 (3/64 in); grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.25; grade 25 | Ruby sphere; diameter(mm), 1.25; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.50; grade 25 | Ruby sphere; diameter(mm), 1.50; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.59 (1/16in); grade 25 | Ruby sphere; diameter(mm), 1.59 (1/16in); grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 1.75; grade 25 | Ruby sphere; diameter(mm), 1.75; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 2.00; grade 25 | Ruby sphere; diameter(mm), 2.00; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 2.38 (3/38in); grade 25 | Ruby sphere; diameter(mm), 2.38 (3/38in); grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 2.50; grade 25 | Ruby sphere; diameter(mm), 2.50; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 3.00; grade 25 | Ruby sphere; diameter(mm), 3.00; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 3.18 (1/8in); grade 25 | Ruby sphere; diameter(mm), 3.18 (1/8in); grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 3.50; grade 25 | Ruby sphere; diameter(mm), 3.50; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 4.00; grade 25 | Ruby sphere; diameter(mm), 4.00; grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 4.76 (3/16in); grade 25 | Ruby sphere; diameter(mm), 4.76 (3/16in); grade 25. Group: Windows & spheres. | |
| Ruby sphere; diameter(mm), 5.00; grade 25 | Ruby sphere; diameter(mm), 5.00; grade 25. Group: Windows & spheres. | |
| Rucaparib | Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699; PF-01367338. CAS No. 283173-50-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10617A. | |
| Rucaparib | Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Synonyms: 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd)indol-6-one; Rucaparib free base, AG-14447; AG 14447; AG14447; Rubraca. Grades: >98%. CAS No. 283173-50-2. Molecular formula: C19H18FN3O. Mole weight: 323.36. | |
| Rucaparib | Rucaparib/ Rubraca is a first-in-class of PARP inhibitors targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1). In December 2016, the U.S. FDA granted an accelerated approval for use in cases of pretreated advanced ovarian cancer. Group: Fluorinated apis. Alternative Names: Rubraca. CAS No. 283173-50-2. Molecular formula: C19H18FN3O. Mole weight: 323.37. Appearance: Off-white powder. Purity: 0.98. IUPACName: 6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one. Catalog: OFC283173502. | |
| Rucaparib Camsylate | Rucaparib camsylate is a PARP inhibitor. Synonyms: Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)-, compd. with 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one (1:x); 8-fluoro-5-(4-((methylamino)methyl)phenyl)-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (1:x); 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:x). Grades: ≥98% by HPLC. CAS No. 1327258-57-0. Molecular formula: C19H18FN3O.xC10H16O4S. Mole weight: 323.37 (free base). | |
| Rucaparib Camsylate | Rucaparib camsylate is a potent, orally available inhibitor of poly ADP-ribose polymerase (PARP) 1 and 2. Group: Inhibitors. Alternative Names: AG14699 (as phosphate salt); AG 14699; AG-14699; AG014447 (as free base); AG-014447; AG 014447; PF01367338; PF-01367338; PF 01367338; Rucaparib camsylate; Rubraca. CAS No. 1859053-21-6. Molecular formula: C29H34FN3O5S. Mole weight: 555.67. Appearance: Solid powder. Purity: >98%. IUPACName: Bicyclo(2.2.1)heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)-, compd. with 8-fluoro-1,3,4,5-tetrahydro-2-(4-((methylamino)methyl)phenyl)-6H-pyrrolo(4,3,2-ef)(2)benzazepin-6-one (1:1). Canonical SMILES: O=S (C[C@@]1 (C2 (C)C)C (C[C@@]2 ([H])CC1)=O) (O)=O. O=C (NCC3)C4=CC (F)=CC5=C4C3=C (C6=CC=C (CNC)C=C6)N5. Catalog: ACM1859053216. | |
| Rucaparib monocamsylate | Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699 monocamsylate; PF-01367338 monocamsylate. CAS No. 1859053-21-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-102003. | |
| Rucaparib phosphate | Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-014699 phosphate; PF-01367338 phosphate. CAS No. 459868-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10617. | |
| Rucaparib phosphate | Rucaparib Phosphate is a selective PARP inhibitor that suppresses the PARP1-mediated DNA repair via binding to PARP1 (Ki = <5 nM). It can be used to sensitize cancer cells to chemotherapy as an antineoplastic agent. Uses: Antineoplastic agent. Synonyms: AG-014699; PF-01367338; AG 014699; PF 01367338; AG014699; PF01367338; Rucaparib (phosphate). Grades:>98%. CAS No. 459868-92-9. Molecular formula: C19H21FN3O5P. Mole weight: 421.365. | |
| RuCl2[(R)-xylbinap][(R)-daipen] | Highly active catalyst for hydrogenation of simple ketones giving high enantioselectivity when sterically unsymmetrical ketones such as acetophenone, heteroaryl ketones, benzophenones, cyclopropyl ketones, and cyclohexyl ketones are substrates. Ee's are enhanced with XylBINAP relative to BINAP. The otherwise poorly bonded ketone is held in the transition state by hydrogen bonding to the protic bidentate amine. Carbonyl groups are selectively reduced even when olefins exist in the same molecule. In the presence of strong base, and catalyst, simple ketones, having substituents at the α-position, may be induced to undergo dynamic kinectic resolution during their hydrogenation to produce two chiral carbon centers in high yield. Group: Heterocyclic organic compound. CAS No. 220114-32-9. Molecular formula: C71H74Cl2N2O2P2Ru. Mole weight: 1221.3. Catalog: ACM220114329. | |
| RuCl2[(S)-xylbinap][(S)-daipen] | Highly active catalyst for hydrogenation of simple ketones giving high enantioselectivity when sterically unsymmetrical ketones such as acetophenone, heteroaryl ketones, benzophenones, cyclopropyl ketones, and cyclohexyl ketones are substrates. Ee's are enhanced with XylBINAP relative to BINAP. The otherwise poorly bonded ketone is held in the transition state by hydrogen bonding to the protic bidentate amine. Carbonyl groups are selectively reduced even when olefins exist in the same molecule. In the presence of strong base, and catalyst, simple ketones, having substituents at the α-position, may be induced to undergo dynamic kinectic resolution during their hydrogenation to produce two chiral carbon centers in high yield. Group: Heterocyclic organic compound. Alternative Names: RuCl2[(S)-(DM-BINAP)][(S)-DAIPEN], 220114-01-2, Dichloro[(S)-(-)-2,2 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-1,1 inverted exclamation marka-binaphthyl][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II). CAS No. 220114-01-2. Molecular formula: C71H74Cl2N2O2P2Ru. Mole weight: 1221.3. Purity: 0.96. IUPACName: [ (2S) -1-azanidyl-1, 1-bis (4-methoxyphenyl) -3-methylbutan-2-yl]azanide; [1-[2-bis (3, 5-dimethylphenyl) phosphaniumylnaphthalen-1-yl]naphthalen-2-yl]-bis (3, 5-dimethylphenyl) phosphanium; dichlororuthenium (2+). Catalog: ACM220114012. | |
| RuCl2[(S)-xylbinap][(S,S)-dpen] | Sequential asymmetric hydrogenation reactions with solution or polymer-bound BINAP/Diamine complexes. Asymmetic hydrogenation of imines. Catalysts for deracemization of benzylic alcohols. Group: Ruthenium series catalysts. Alternative Names: MFCD09753028; RUCL2[(S)-XYLBINAP][(S,S)-DPEN]; RuCl2[(S)-(DM-BINAP)][(S,S)-DPEN]; Dichloro[(S)-(-)-2,2 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-1,1 inverted exclamation marka-binaphthyl][ (1S, 2S)- (-)-1, 2-diphenylethylenediamine]ruthenium (II); Dichloro{ (S)- (-)-2, 2'-bis[di (3, 5-xylyl)phosphino]-1, 1'-binaphthyl}[ (1S, 2S)- (-)-1, 2-diphenylethylenediamine]ruthenium (II); (S)-DM-BINAP RuCl2 (S,S)-DPEN; C66H64N2P2Ru Cl2. CAS No. 220114-03-4. Molecular formula: C66H64Cl2N2P2Ru. Mole weight: 1119.17g/mol. IUPACName: [1-[2-bis(3, 5-dimethylphenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-bis(3, 5-dimethylphenyl)phosphane; dichlororuthenium; (1S, 2S)-1, 2-diphenylethane-1, 2-diamine. Canonical SMILES: CC1=CC (=CC (=C1)P (C2=C (C3=CC=CC=C3C=C2)C4=C (C=CC5=CC=CC=C54)P (C6=CC (=CC (=C6)C)C)C7=CC (=CC (=C7)C)C)C8=CC (=CC (=C8)C)C)C. C1=CC=C (C=C1)C (C (C2=CC=CC=C2)N)N. Cl[Ru]Cl. Catalog: ACM220114034. | |
| RuCl(p-cymene)[(R,R)-Ts-DPEN] | This catalyst has shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are dialkylamino, hydoxy, siloxy, carbonyl, ester, amide or thioester. Alternative Names: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(p-cymene)ruthenium(II). CAS No. 192139-92-7. Molecular formula: C21H21ClN2O2RuS.C10H14. Mole weight: 636.21. Appearance: Orange yellow powder. Purity: 0.98. Catalog: ACM192139927. | |
| RuCl[(R,R)-Fsdpen](p-cymene) | Catalyst used in the asymmetric transfer hydrogenation of ketones using formic acid-triethylamine mixture. Group: Ruthenium series catalysts. Alternative Names: 1026995-71-0; RuCl [ (R, R) -FsDPEN] (p-cymene ) ; Chloroaminodiphenyl ethyl pentafluorophenyl ksulfonyl ) amido ( (p-cymene ) ruthenium (II) ) ; SCHEMBL1669799; MFCD12545953; RuCl [ (R, R) -FsDPEN] (p-cymene ) , 90% ; [N- [ (1R, 2R) -2- (Amino-|EN) -1, 2-diphenylethyl] -2, 3, 4, 5, 6-pentafluorobenzenesulfonamidato-|EN] chloro [ (1, 2, 3, 4, 5, 6-|C) -1-methyl-4- (1-methylethyl) benzene] -ruthenium; Chloro{ [ (1R, 2R) - (-) -2-amino-1, 2-diphenylethyl] (4-pentafluorophenylsulfonyl) amido{ (p-cymene) ruthenium (II). CAS No. 1026995-71-0. Molecular formula: C30H28ClF5N2O2RuS. Mole weight: 712.138g/mol. IUPACName: [(1R, 2R)-2-amino-1, 2-diphenylethyl]-(2, 3, 4, 5, 6-pentafluorophenyl)sulfonylazanide; chlororuthenium(1+); 1-methyl-4-propan-2-ylbenzene. Canonical SMILES: CC1=CC=C (C=C1)C (C)C. C1=CC=C (C=C1)C (C (C2=CC=CC=C2)[N-]S (=O) (=O)C3=C (C (=C (C (=C3F)F)F)F)F)N. Cl[Ru+]. Catalog: ACM1026995710. | |
| RuCl[(R,R)-Tsdpen](mesitylene) | Catalyst used in the asymmetric transfer hydrogenation of ketones using formic acid-triethylamine mixture. Group: Heterocyclic organic compound. Alternative Names: 174813-82-2; RuCl[ (R, R)-TsDPEN] (mesitylene); R0127; [ (R, R)-N- (2-Amino-1, 2-diphenylethyl)-p-toluenesulfonamide]chloro (mesitylene)ruthenium (II); Chloro (mesitylene)[ (R, R)-N- (p-toluenesulfonyl)-1, 2-diphenylethylenediamine]ruthenium (II); chloro[ (1r, 2r)-n- (p-toluenesulfonyl)-1, 2-diphenylethanediamine] (mesitylene)ruthenium (II). CAS No. 174813-82-2. Molecular formula: C30H33ClN2O2RuS. Mole weight: 622.186g/mol. IUPACName: [(1R, 2R)-2-amino-1, 2-diphenylethyl]-(4-methylphenyl)sulfonylazanide; ruthenium(2+); 1, 3, 5-trimethylbenzene; chloride. Canonical SMILES: CC1=CC=C (C=C1)S (=O) (=O)[N-]C (C2=CC=CC=C2)C (C3=CC=CC=C3)N. CC1=CC (=CC (=C1)C)C. [Cl-]. [Ru+2]. Catalog: ACM174813822. | |
| RuCl[(S,S)-Fsdpen](p-cymene) | Catalyst used in the asymmetric transfer hydrogenation of ketones using formic acid-triethylamine mixture. Group: Ruthenium series catalysts. Alternative Names: RuCl[ (S, S) -FsDPEN] (p-cymene) ; 1026995-72-1; [ (S, S) -N- (2-Amino-1, 2-diphenylethyl) pentafluorobenzenesulfonamide]chloro (p-cymene) ruthenium (II) ; R0122; J-000770; Chloro (p-cymene) [ (S, S) -N- (pentafluorobenzenesulfonyl) -1, 2-diphenylethylenediamine]ruthenium (II) ; Chloro{[ (1S, 2S) - (+) -2-amino-1, 2-diphenylethyl] (pentafluorophenylsulfonyl) amido} (p-cymene) ruthenium (I. CAS No. 1026995-72-1. Molecular formula: C30H28ClF5N2O2RuS. Mole weight: 712.138g/mol. IUPACName: [(1S,2S)-2-amino-1,2-diphenylethyl]-(2,3,4,5,6-pentafluorophenyl)sulfonylazanide;1-methyl-4-propan-2-ylbenzene;ruthenium(2+);chloride. Canonical SMILES: CC1=CC=C (C=C1)C (C)C. C1=CC=C (C=C1)C (C (C2=CC=CC=C2)[N-]S (=O) (=O)C3=C (C (=C (C (=C3F)F)F)F)F)N. [Cl-]. [Ru+2]. Catalog: ACM1026995721. | |
| RuCl[(S,S)-Tsdpen](mesitylene) | Catalyst used in the asymmetric transfer hydrogenation of ketones using formic acid-triethylamine mixture. Group: Ruthenium series catalysts. Alternative Names: RuCl[(S, S)-TsDPEN](mesitylene); 174813-81-1; CTK8E7375; KS-000018VY; RT-015463; J-011043; Ruthenium, [N-[(1S,2S)-2-(amino-kappaN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-kappaN]chloro[(1,2,3,4,5,6-eta)-1,3,5-trimethylbenzene]-. CAS No. 174813-81-1. Molecular formula: C30H33ClN2O2RuS. Mole weight: 622.186g/mol. IUPACName: [(1S, 2S)-2-amino-1, 2-diphenylethyl]-(4-methylphenyl)sulfonylazanide; chlororuthenium(1+); 1, 3, 5-trimethylbenzene. Canonical SMILES: CC1=CC=C (C=C1)S (=O) (=O)[N-]C (C2=CC=CC=C2)C (C3=CC=CC=C3)N. CC1=CC (=CC (=C1)C)C. Cl[Ru+]. Catalog: ACM174813811. | |
| Rucosopasem Manganese | Rucosopasem manganese is a superoxide dismutase (SOD) mimic. Synonyms: FW5T90VM32; GC-4419 dipropionate; Bis-propionato(gc4419); Avasopasem manganese dipropionate. Grades: >98%. CAS No. 2248030-85-3. Molecular formula: C27H45MnN5O4. Mole weight: 558.6. | |
| Rufinamide | Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 106308-44-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C10H8F2N4O, Form: Supplied as a white. US Biological Life Sciences. | Worldwide |
| Rufinamide | Rufinamide (E 2080; CGP 33101; RUF 331) is a novel anticonvulsant compound that can inhibit Na + current activation, and be used in the research of Lennox-Gastaut syndrome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 33101; E 2080; RUF 331. CAS No. 106308-44-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0042. | |
| Rufinamide | Rufinamide (E 2080; CGP 33101; RUF 331) is a new antiepileptic agent that differs structurally from other antiepileptic drugs and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS). Uses: Anticonvulsants. Synonyms: CGP-33101; CGP 33101; CGP33101; E 2080; RUF 331; Inovelon; Banzel; E2080; RUF331; E-2080; RUF-331. Grades: 0.99. CAS No. 106308-44-5. Molecular formula: C10H8F2N4O. Mole weight: 238.19. | |
Our database is helping our users find suppliers everyday.
