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| Product | Description | |
|---|---|---|
| Selenium (VI) Fluoride | SELENIUM (VI) FLUORIDE, 99.5% pure, gas, (Synonym: Selenium Hexafluoride), Formula: SeF6. CAS No. 7783-79-1. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! |  Texas TX |
| Selenium XRF Standard - 0.47 wt% | certified reference material. Group: Certified reference materials (crms). |  |
| Selenium Yeast 0.2% Powder | Selenium Yeast 0.2% Powder . |  CA, FL & NJ |
| Selenius Acid | Selenius Acid. CAS No. 7783-00-8. Product ID: 2-08384. Molecular formula: H2SeO3. Mole weight: 128.97. Categories: Selenous acid. |  |
| Selenius Acid USP | Selenius Acid USP. CAS No. 7783-00-8. Product ID: 2-08497. Molecular formula: H2SeO3. Mole weight: 128.97. Purity: 0.98. | |
| Selenocyanatoacetic acid | Selenocyanatoacetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SELENOCYANATOACETIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 19188-17-1. Molecular formula: C3H3NO2Se. Mole weight: 164.02. Product ID: ACM19188171. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Selenocysteine | Selenocysteine. CAS No. 10236-58-5. Product ID: 2-08417. Molecular formula: C3H6NO2Se. Mole weight: 167.05. | |
| selenocysteine lyase | A pyridoxal-phosphate protein. Dithiothreitol or 2-mercaptoethanol can act as the reducing agent in the reaction. The enzyme from animals does not act on cysteine, serine or chloroalanine, while the enzyme from bacteria shows activity with cysteine (cf. EC 2.8.1.7, cysteine desulfurase). Group: Enzymes. Synonyms: selenocysteine reductase; selenocysteine β-lyase. Enzyme Commission Number: EC 4.4.1.16. CAS No. 82047-76-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5318; selenocysteine lyase; EC 4.4.1.16; 82047-76-5; selenocysteine reductase; selenocysteine β-lyase. Cat No: EXWM-5318. |  |
| selenocysteine Se-methyltransferase | The enzyme uses S-adenosyl-L-methionine as methyl donor less actively than S-methyl-L-methionine. The enzyme from broccoli (Brassica oleracea var. italica) also has the activity of EC 2.1.1.10, homocysteine S-methyltransferase. Group: Enzymes. Synonyms: SMT. Enzyme Commission Number: EC 2.1.1.280. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1887; selenocysteine Se-methyltransferase; EC 2.1.1.280; SMT. Cat No: EXWM-1887. | |
| Selenocystine | Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment [1]. Uses: Scientific research. Group: Peptides. CAS No. 2897-21-4. Pack Sizes: 10 mg; 25 mg. Product ID: HY-113064. |  |
| SELENO-DIGLUTATHIONE | Synonyms: l-glutamine,n,n'-(selenobis(thio(1-(((carboxymethyl)amino)carbonyl)-2,1-etha; n, n'- ( (selenodithio) bis (1- ( (carboxymethyl) carbamoyl) ethylene) ) di-glutaminl; nediyl)))bis-; 2,2'-SELENOBIS(L-GAMMA-GLUTAMYL-L-CYSTEINYLGLYCINE); S,S'-SELENOBISGLUTATHIONE; SELENO-DIG. CAS No. 33944-90-0. Molecular formula: C20H32N6O12S2Se. Mole weight: 691.59. |  |
| Seleno-D,L-ethionine | Used as a substrate for methionine adenosyltransferase from rat liver. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Seleno-DL-ethionine | Seleno-DL-ethionine. CAS No: 2578-27-0 |  Sarchem Laboratories New Jersey NJ |
| Seleno-L-methionine | Seleno-L-methionine. CAS No: 3211-76-5 | Sarchem Laboratories New Jersey NJ |
| Seleno-L-methionine | ?98% (TLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Seleno L Methionine 5,000 MCG/G | Seleno L Methionine 5,000 MCG/G. | CA, FL & NJ |
| Selenomethionine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Selenomethionine | Selenomethionine is an essential nutrient that may have a role in other biologically active compounds, especially vitamin E and the enzyme formic dehydrogenase. Synonyms: DL-Selenomethionine; Selenomethionine; Seleno-DL-methionine; (+-)-Selenomethionine; 2578-28-1; 2-amino-4-(methylselanyl)butanoicacid. Grades: 95%. CAS No. 1464-42-2. Molecular formula: C5H11NO2Se. Mole weight: 196.11. | |
| Selenomethionine | Selenomethionine is used in the anticancer/antitumor drug combinations in an effort to minimize tumor sizes and improve survivability of breast cancer patients. Also used in the treatment of autoimmune thyroiditis, acting through eurothyroidism it reduces thyroid stimulating hormone levels (TSH). Group: Biochemicals. Grades: Highly Purified. CAS No. 1464-42-2. Pack Sizes: 25mg, 100mg. Molecular Formula: C5H11NO2Se. US Biological Life Sciences. | Worldwide |
| Selenomethionine | Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Seleno-DL-methionine; DL-Selenomethionine. CAS No. 1464-42-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B1000. | |
| Selenomethionine USP | Selenomethionine USP. CAS No. 3211-76-5. Molecular formula: C5H11NO2Se. |  |
| Selenophene | 1g Pack Size. Group: Building Blocks, Research Organics & Inorganics. Formula: C4H4Se. CAS No. 288-05-1. Prepack ID 76723073-1g. Molecular Weight 131.03. See USA prepack pricing. |  |
| Selenophene-2-boronic acid | Selenophene-2-boronic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RARECHEM AH PB 0118;selenophen-2-ylboronic acid;SELENOPHENE-2-BORONIC ACID. Product Category: Boronic Acids. CAS No. 35133-86-9. Molecular formula: C4H5BO2Se. Mole weight: 174.85. Purity: 0.98. Density: g/cm³. Product ID: ACM35133869. Alfa Chemistry ISO 9001:2015 Certified. | |
| Selenosulfuric Acid Dipotassium Salt | Selenosulfuric Acid Dipotassium Salt is used in the synthesis of CdSe photocatalysts with enhanced photocatalytic ativitys. Possible application towards industrial wastewater treatment and pollutant removal. Group: Biochemicals. Alternative Names: Dipotassium Selenosulfate; potassium selenosulfate; potassium selenosulfate (K2SeSO3). Grades: Purified. CAS No. 15571-89-8. Pack Sizes: 50mg. Molecular Formula: K2O3SSe, Molecular Weight: 237.22. US Biological Life Sciences. | Worldwide |
| Selenous Acid | SELENOUS ACID, 65% SOLUTION, 99% pure, 39.8% Se, Formula: H2SeO3. CAS No. 7783-00-8. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! | Texas TX |
| Selenous Acid | SELENOUS ACID, 99% pure, -4 mesh, Formula: H2SeO3. CAS No. 7783-00-8. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! | Texas TX |
| Selenous (Selenous) Acid | Selenous (Selenous) Acid. Group: Biochemicals. Alternative Names: Selenious Acid; Selenium dioxide, hydrated. Grades: Molecular Biology Grade. CAS No. 7783-00-8. Pack Sizes: 25g. Molecular Formula: H2SeO3, Molecular Weight: 128.97. US Biological Life Sciences. | Worldwide |
| Selepag impurity 5 | Selepag impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1693685-49-2. Molecular formula: C7H16ClN. Mole weight: 149.66. Catalog: APB1693685492. | |
| Selepressin | Selepressinis is an agonist of the vasopressin 1A receptor and can be used to treat vasodilatory hypotension in septic shock. Synonyms: Cbz-Phe-Ala-CH2F; Z-FA-fluoromethyl ketone; Zfa-fmk; Z-Phe-Ala-fluoromethyl ketone; benzyloxycarbonyl-Phe-Ala-fluormethylketone; Cathepsin B inhibitor. Grades: ≥95%. CAS No. 876296-47-8. Molecular formula: C21H23FN2O4. Mole weight: 386.42. | |
| Selepressin | Selepressin (FE 202158) is a selective vasopressin V 1A receptor agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock [1] [2] [4]. Uses: Scientific research. Group: Peptides. Alternative Names: FE 202158. CAS No. 876296-47-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105239. | |
| Seletalisib | Seletalisib is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by UCB. It is an immunomodulator. Phaes I clinical trials for Plaque psoriasis, phaes II clinical trials for Sjogren's syndrome and phaes III clinical trials for Immunodeficiency disorders is on-going. Synonyms: UCB-5857; UCB 5857; UCB5857; (R)-3-(8-chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide. Grades: 98%. CAS No. 1362850-20-1. Molecular formula: C23H14ClF3N6O. Mole weight: 482.85. | |
| Seletracetam | Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ucb 44212. CAS No. 357336-74-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119810. | |
| Selexipag | Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin ( PGI 2 ) receptor (IP receptor). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS-304; ACT-293987. CAS No. 475086-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14870. | |
| Selfotel | Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA) -preferring receptor. CGS 19755 inhibits the binding of [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to NMDA-type receptors with an IC 50 of 50 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGS 19755. CAS No. 110347-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15086. | |
| Seliciclib | Seliciclib is an orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic and antineoplastic activities. Seliciclib primarily inhibits CDK2/E, CDK2/A, CDK7 and CDK9 by competing for their ATP binding sites, leading to a disruption of cell cycle progression. In addition, this agent appears to interfere with CDK-mediated phosphorylation of the carboxy-terminal domain of RNA polymerase II, inhibiting RNA polymerase II-dependent transcription, which may result in the down-regulation of antiapoptotic proteins such as induced myeloid leukemia cell differentiation protein Mcl-1. CDKs, serine/threonine kinases that play an important role in cell cycle regulation, are overexpressed in various malignancies. Mcl-1 belongs to the Bcl-2 family of antiapoptotic proteins and is a protein crucial to the survival of a range of tumor cell types. Synonyms: R-roscovitine. CYC202; CYC202; CYC 202; R-Roscovitine; Roscovitin; Roscovitine; Seliciclib. R-Roscovitine; Roscovitin; Roscovitine. Grades: >98%. CAS No. 186692-46-6. Molecular formula: C19H26N6O. Mole weight: 354.44. | |
| Selicrelumab | Selicrelumab is an agonistic CD40 monoclonal antibody. Selicrelumab binds to CD40 present on the surfaces of some solid tumor cells, leading to apoptosis and decreased tumor growth. CAS No. 1622140-49-1. | |
| Selicrelumab | Selicrelumab is an agonist CD40 antibody, induces changes in the tumor microenvironment. Selicrelumab can be used for the research of pancreatic cance and neoadjuvant study [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1622140-49-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99046. | |
| Seliforant | Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SENS-111. CAS No. 1164115-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109074. | |
| Selinexor | Selinexor Inhibitor. Uses: Scientific use. Product Category: T6106. CAS No. 1393477-72-9. |  |
| Selinexor | Selinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein/exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells. Synonyms: KPT-330; KPT 330; KPT330; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-; Xpovio; (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide. Grades: ≥95%. CAS No. 1393477-72-9. Molecular formula: C17H11F6N7O. Mole weight: 443.31. | |
| Selinexor | Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-330. CAS No. 1393477-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17536. | |
| Selisistat | Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC 50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EX-527. CAS No. 49843-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15452. | |
| Selitrectinib | Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC 50 s of 0.6 nM and <2.5 nM for TRKA and TRKC , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-195. CAS No. 2097002-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101977. | |
| Seliwanoff Reagent, Laboratory Grade, 100 mL | Storage Code: White; corrosive. Grades: chem-grade laboratory. Product ID: 887365. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Selonsertib | Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Synonyms: 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide; GS-4997; GS4997; GS 4997. Grades: ≥98%. CAS No. 1448428-04-3. Molecular formula: C24H24FN7O. Mole weight: 445.5. | |
| Selonsertib | Selonsertib (GS-4997), an orally bioavailable, selective apoptosis signal-regulating kinase 1 ( ASK1 ) inhibitor with a pIC 50 of 8.3, has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-4997. CAS No. 1448428-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18938. | |
| Selpercatinib | Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC 50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-292. CAS No. 2152628-33-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114370. | |
| Selpercatinib | Selpercatinib is a selective RET inhibitor with antineoplastic activity. It inhibits proliferation of cancer cells containing RET mutations or gene fusions. It is indicated for the treatment of non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC) and other thyroid cancer tumors. Synonyms: LOXO-292; LOXO292; LOXO 292; ARRY-192; ARRY192; ARRY 192. CAS No. 2152628-33-4. Molecular formula: C29H31N7O3. Mole weight: 525.6. | |
| SelSA | SelSA is a selective, orally active inhibitor for histone deacetylase 6 ( HDAC6 ) with IC 50 of 56.9 nM. SelSA inhibits the phosphorylation of ERK1/2. SelSA inhibits the proliferation of breast cancer cells and hepatocellular carcinoma cells with IC 50 of 0.58-2.6 μM, inhibits cell migration and invasion of Huh7, and induces apoptosis. SelSA exhibits antitumor activity in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1225038-92-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162616. | |
| Seltorexant | Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922. CAS No. 1293281-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012. | |
| Seltorexant hydrochloride | Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922 hydrochloride. CAS No. 1293284-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012A. | |
| Selumetinib | Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent. Synonyms: ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886. Grades: >98%. CAS No. 606143-52-6. Molecular formula: C17H15BrClFN4O3. Mole weight: 457.684. | |
| Selumetinib | Selumetinib. Group: Biochemicals. Alternative Names: 5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide; ARRY 142886; AZD 6244. Grades: Highly Purified. CAS No. 606143-52-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C17H15BrClFN4O3. US Biological Life Sciences. | Worldwide |
| Selumetinib | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244; ARRY-142886. CAS No. 606143-52-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706. | |
| Selumetinib sulfate | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244 sulfate; ARRY-142886 sulfate. CAS No. 943332-08-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706A. | |
| Selurampanel | Selurampanel (BGG 492) is an orally active and competitive AMPA receptor antagonist with an IC 50 of 190 nM. Selurampanel has reasonable blood-brain barrier penetration. Selurampanel can be used for epilepsy research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGG 492. CAS No. 912574-69-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-105860. | |
| Selvigaltin | Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC 50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB1211. CAS No. 1978336-95-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147041. | |
| SEMA4D/CD100 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Semagacestat | Semagacestat is an inhibitor of the γ-secretase complex that blocks the production of Aβ38 (IC50= 12.0 nM), Aβ40 (IC50= 12.1 nM), and Aβ42 (IC50= 10.9 nM) from H4 human glioma cells stably overexpressing human wild-type APP into the culture medium. In vitro: blocks the production of Aβ38 (IC50= 12.0 nM), Aβ40 (IC50= 12.1 nM), and Aβ42 (IC50= 10.9 nM) without affecting cell viability. In vivo: decreases hippocampal levels of both Aβ42 and Aβ40 at 10 mg/kg (22-23% reduction) and 30 mg/kg (36-41% reduction) and increases β-CTF at 0.3-10 mg/kg in a dose dependent manner with no inhibition on the processing of other γ-secretase substrates, such as Notch, N-cadherin or EphA4, in the brain, but impairs normal cognition in wild-type mice and 3-month-old Tg2576 mice failing to restore cognitive deficits in the Y-maze test. Uses: Gamma secretase inhibitors and modulators. Synonyms: (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide; LY 411,575; LY 411575; LY 450139; LY-411,575; LY-411575; LY411,575; LY411575; LY450139; N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; LY4501; LY-4501; LY 4501; LY450139; LY-450139; LY 450139; Semagacestat. 425386-60-3. Grades: >98%. CAS No. 425386-60-3. Molecular formula: C19H27N3O4. Mole weight: 361.44. | |
| Semagacestat | Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (A β), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD). Group: Biochemicals. Alternative Names: (2S) -2-Hydroxy-3-methyl-N- [ (1S) -1-methyl-2-oxo-2- [ [ (1S) -2, 3, 4, 5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl] amino] ethyl] butanamide; LY 450139. Grades: Highly Purified. CAS No. 425386-60-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Semagacestat | Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid ( Aβ42 ), Aβ38 and Aβ40 with IC 50 s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC 50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY450139. CAS No. 425386-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10009. | |
| Semaglutide | Semaglutide Inhibitor. Uses: Scientific use. Product Category: T19850. CAS No. 910463-68-2. | |
| Semaglutide | H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. CAS No. 910463-68-2. Product ID: 8-04992. Molecular formula: C187H291N45O59. Mole weight: 4113.6. MFCD No. agonist of glucagon-like peptide 1 receptor. | |
| Semaglutide | Semaglutide. Categories: semaglutide; ozempic. | CA, FL & NJ |
| Semaglutide | Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 910463-68-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118. | |
| Semaglutide | Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide. Uses: The treatment of type 2 diabetes. Synonyms: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; BGM 134; NN 9535; NN 9536; NNC 0113-0217; Ozempic; Rybelsus; Wegovy; (3S, 9S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S, 36S, 39S, 45S, 48S, 51S, 54S, 81S)-54-(((6S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S)-21-(.. Grades: >98%. CAS No. 910463-68-2. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Semaglutide acetate | Semaglutide acetate. CAS No. 1997361-85-9. Product ID: 8-04994. Molecular formula: C187H291N45O59; xC2H4O2. Mole weight: 4113.6. | |
| Semaglutide acetate | Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 1997361-85-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118B. | |
| Semaglutide-[d15] | Semaglutide-[d15] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide-d15; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu(D7)-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H276D15N45O59. Mole weight: 4128.73. | |
| Semaglutide Impurity 10 | Semaglutide Impurity 10 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C188H291N45O61. Mole weight: 4157.65. | |
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