American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

Search for products or services, then visit the suppliers website for prices or more information.

Product
SEW 2871 SEW 2871. Group: Biochemicals. Grades: Purified. CAS No. 256414-75-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SEW?2871 SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC 50 of 13.8 nM. SEW2871 activates ERK , Akt , and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood. SEW2871 can be used for the research of diabetes, Alzheimers disease, liver fibrosis, and inflammatory responses [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 256414-75-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W008947. MedChemExpress MCE
Sewage sludge (content in PCDDs, PCDFs) certified Reference Material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Sewage sludge (industrial origin) (trace elements) certified Reference Material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Sewage sludge (mixed origin) (trace elements) certified Reference Material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Sewage Suction Hose Sewage Suction Hose. Group: Polymers. Alfa Chemistry Materials 3
SEX PHEROMONE INHIBITOR IPD1 Sex pheromone inhibitor ipd1 is produced by Streptococcus faecalis donor strains harboring bacteriocin plasmid pPD1. It inhibits the activity of sex pheromone cPD1. Synonyms: H-Ala-Leu-Ile-Leu-Thr-Leu-Val-Ser-OH. Grade: 95%. CAS No. 120116-56-5. Molecular formula: C39H72N8O11. Mole weight: 829.04. BOC Sciences
SF 11 SF 11. Group: Biochemicals. Grades: Purified. CAS No. 443292-81-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SF 11 SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist ( IC 50 =199 nM). Antidepressant-like activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 443292-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107731. MedChemExpress MCE
SF-11 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
SF 1126 SF 1126. Group: Biochemicals. Alternative Names: N2-[1,4-Dioxo-4-[[4-(4-oxo-8-phenyl-4H-1-benzopyran-2-yl)morpholinium-4-yl]methoxy]butyl]-L-arginylglycyl-L-α-aspartyl-L-serine Inner Salt. Grades: Highly Purified. CAS No. 936487-67-1. Pack Sizes: 1mg. Molecular Formula: C39H48N8O14, Molecular Weight: 852.84. US Biological Life Sciences. USBiological 3
Worldwide
SF-1623 SF-1623 is a cephamycin antibiotic produced by the the fermentation of Streptomyces chartreusis. It is active against gram-negative bacteria. Synonyms: SF 1623. CAS No. 56487-86-6. Molecular formula: C15H21N3O10S3. Mole weight: 499.5. BOC Sciences 12
SF1670 SF1670 is a potent and specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 345630-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15842. MedChemExpress MCE
SF1670 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
SF-20 from mouse recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
SF-22 SF-22 is a potent and brain-penetrant antagonist of neuropeptide Y receptor (Y2R), with the IC 50 value of 750 nM. SF-22 plays an important role in neurological disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824981-55-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132240. MedChemExpress MCE
SF-22 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
SF 2315 A SF 2315 A is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 100 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315A; SF 2315A; SF2315A; cis-(+)-4a,5,6,12b-Tetrahydro-4a,8-dihydroxy-3-methylbenz(a)anthracene-1,7,12(4H)-trione. CAS No. 114687-52-4. Molecular formula: C19H16O5. Mole weight: 324.3. BOC Sciences 12
SF 2315 B SF 2315 B is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 40 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315B; SF 2315B; SF2315B. CAS No. 114687-53-5. Molecular formula: C19H20O5. Mole weight: 344.4. BOC Sciences 12
SF-2330 SF-2330 is a quinone antibiotic produced by Streptomyces sp. SF-2330. It exhibits activity against gram-positive bacteria. Synonyms: Antibiotic SF-2330; SF 2330; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 2-(2,2'-bioxiran)-2-yl-11-hydroxy-5-methyl-. CAS No. 103947-06-4. Molecular formula: C22H14O7. Mole weight: 390.3. BOC Sciences 12
SF-2415A1 SF-2415A1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A1; SF 2415A1. CAS No. 110200-32-3. Molecular formula: C26H31ClN2O5. Mole weight: 487. BOC Sciences 12
SF-2415A2 SF-2415A2 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A2; SF 2415A2. CAS No. 110200-31-2. Molecular formula: C26H30N2O5. Mole weight: 450.5. BOC Sciences 12
SF-2415A3 SF-2415A3 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A3; SF 2415A3. CAS No. 110200-33-4. Molecular formula: C26H30Cl2N2O5. Mole weight: 521.4. BOC Sciences 12
SF-2415B1 SF-2415B1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B1; SF 2415B1. CAS No. 110200-34-5. Molecular formula: C26H33ClO5. Mole weight: 461. BOC Sciences 12
SF-2415B2 SF-2415B2 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B2; SF 2415B2. Molecular formula: C26H32O5. Mole weight: 424.53. BOC Sciences 12
SF-2415B3 SF-2415B3 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B3; SF 2415B3. Molecular formula: C26H32Cl2O5. Mole weight: 495.43. BOC Sciences 12
SF 2446A1 SF 2446A1 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446A1; SF2446A1. Molecular formula: C34H35NO15. Mole weight: 697.6. BOC Sciences 12
SF 2446A2 SF 2446A2 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446A2; SF2446A2. Molecular formula: C34H35NO15. Mole weight: 697.6. BOC Sciences 12
SF 2446A3 SF 2446A3. Synonyms: SF2446A3. CAS No. 115834-24-7. Molecular formula: C26H21NO11. Mole weight: 523.4. BOC Sciences 12
SF 2446B1 SF 2446B1 is a quinone antibiotic produced by Steptomyces sp. SF2446. SF 2446A1, SF 2446A2, SF 2446B1 have potent activity against mycoplasma with MIC of 0.01-0.03μg/mL, and activity against gram-positive bacteria. Synonyms: Antibiotic SF 2446B1; SF2446B1. Molecular formula: C34H35NO14. Mole weight: 681.6. BOC Sciences 12
SF 2446B2 SF 2446B2. Synonyms: SF2446B2. Molecular formula: C34H35NO14. Mole weight: 681.6. BOC Sciences 12
SF2457 SF2457 is an antibiotic related to amicetin, which is isolated from the fermentation broth of Nocardia brasiliensis SF2457. It exhibits inhibitory activity against Gram-positive and Gram-negative bacteria. Synonyms: SF-2457; SF 2457. CAS No. 115748-04-4. Molecular formula: C27H38N6O9. Mole weight: 590.6. BOC Sciences 12
SF 2487 SF 2487 is a polyether antibiotic produced by Actinomadura sp. SF2487. It has moderate activity against gram-positive bacteria including staphylococcus and enterococcus with MIC of 0.10-0.39 μg/mL. It also effective against Influenza A virus. Synonyms: SF-2487; SF2487; SF 2487 sodium salt; Antibiotic SF 2487 sodium salt; LS-70212. Molecular formula: C42H63NaO12. Mole weight: 782.9. BOC Sciences 12
SF2523 SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3K?, PI3K?, DNA-PK, BRD4 and mTOR, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1174428-47-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101146. MedChemExpress MCE
SF2738C SF2738C is an antibiotic produced by the strain of Streptomyces sp. It has moderate activity against gram-positive, gram-negative bacteria and fungi. Synonyms: SF-2738C; SF 2738C. Molecular formula: C13H14N2O2S. Mole weight: 262.33. BOC Sciences 12
SF34 SF34. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(9,9'-Spirofluorenyl-4-yl)-9,9'-spirofluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1799329-54-6. Molecular formula: C50H30. Mole weight: 630.77 g/mol. Product ID: ACM1799329546. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
SF3PO SF3PO. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(9,9-spirobifluorene-3-yl)-phenylphosphane oxide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1454615-69-0. Molecular formula: C37H25OP. Mole weight: 516.57 g/mol. Product ID: ACM1454615690. Alfa Chemistry — ISO 9001:2015 Certified. Categories: SF poetry. Alfa Chemistry. 2
SF3-TRZ SF3-TRZ. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(9,9'-spirobi[fluoren]-3-yl)-4,6-diphenyl-1,3,5-triazine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1639424-37-5. Molecular formula: C40H25N3. Mole weight: 547.65 g/mol. Product ID: ACM1639424375-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
SF5 SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2-Diphenylethyl isothiocyanate. CAS No. 34634-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116794. MedChemExpress MCE
SF-773α SF-773α is an antibiotic produced by Streptomyces sp. It is active against gram-positive bacteria. Synonyms: SF 773α. Molecular formula: C17H34N4O10. Mole weight: 454.5. BOC Sciences 12
SfaN I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GCATC(N)5↑ CGTAG(N)9&darr. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned SfaN I gene from Streptococcus faecalis N. Pack: 10 mM Tris-HCl (pH 7.5); 300 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1172RE. Creative Enzymes
s-Fexofenadine s-Fexofenadine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-FEXOFENADINE;S-Carboxyterfenadine,S-Terfenadinecarboxylate;Benzeneacetic acid, 4-[(1S)-1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-;Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dime. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 139965-11-0. Molecular formula: C32H39NO4. Mole weight: 501.663. Product ID: ACM139965110. Alfa Chemistry — ISO 9001:2015 Certified. Categories: (S)-Fexofenadine. Alfa Chemistry. 3
S-Fexofenadine (S-Carboxyterfenadine, S-Terfenadinecarboxyl ate) A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: S-Carboxyterfenadine, S-Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
SFI003 SFI003 is a SRSF3 inhibitor that drives CRC cell apoptosis via the SRSF3/DHCR24/ROS axis and exhibits potent antitumor effects both in vitro and in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2361332-90-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148660. MedChemExpress MCE
Sfi I One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 70% of the dna fragments can be ligated and recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 1000U; 5000U. GGCCNNNN↑NGGCC CCGGN↓NNNNCCGG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer G, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Sfi I from Streptomyces fimbriatus. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1173RE. Creative Enzymes
SFK1 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
s-(+)-Flecainide s-(+)-Flecainide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(2S)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide. Product Category: Heterocyclic Organic Compound. CAS No. 99495-92-8. Molecular formula: C17H20F6N2O. Mole weight: 414.34. Product ID: ACM99495928. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
S-(+)-Flecainide S-(+)-Flecainide. Group: Biochemicals. Alternative Names: N-[ (2S) -2-Piperidinylmethyl]-2, 5-bis (2, 2, 2-trifluoroethoxy) benzamide. Grades: Highly Purified. CAS No. 99495-92-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H20F6N2O3. US Biological Life Sciences. USBiological 7
Worldwide
S-formylglutathione hydrolase Also hydrolyses S-acetylglutathione, but more slowly. Group: Enzymes. Enzyme Commission Number: EC 3.1.2.12. CAS No. 83380-83-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3547; S-formylglutathione hydrolase; EC 3.1.2.12; 83380-83-0. Cat No: EXWM-3547. Creative Enzymes
SF-PDI Band gap: 2.1 eV. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 1-(3-Butoxycarbonylpropyl)-1-phenyl-[6.6]C61. CAS No. 1643842-69-6. Pack Sizes: 100 mg in glass bottle. Molecular formula: 1822.44. Mole weight: C125H136N4O8. O=C1N (C (CCCCCC) CCCCCC) C (C2=C (C1=CC=C3C4=C (C (C=C5) =CC6=C5C (C=CC (C7=CC8=C9C% 10=C7C% 11=C% 12C (C% 13=CC=C% 12C% 10=CC=C9C (N (C (CCCCCC) CCCCCC) C8=O) =O) =C (C (N (C (CCCCCC) CCCCCC) C% 13=O) =O) C=C% 11) =C% 14) =C% 14C6% 15C% 16=CC=CC=C% 16C% 17=C% 15C=CC=C% 17) C=C (C (N (C (CCCCCC) CCCCCC) C. InChI=1S / C125H136N4O8 / c1-9-17-25-33-45-79 (46-34-26-18-10-2) 126-117 (130) 93-67-61-87-89-63-69-97-113-101 (123 (136) 128 (121 (97) 134) 81 (49-37-29-21-13-5) 50-38-30-22-14-6) 75-99 (109 (115 (89) 113) 91-65-71-95 (119 (126) 132) 111 (93) 107 (87) 91) 77-57-59-85-86-60-58-78 (74-106 (86) 125 (105 (85) 73-77) 103-55-43-41-53-83 (103) 84-54-42-44-56-104 (84) 125) 100-76-102-114-98 (122 (135) 129 (124 (102) 137) 82 (51-39-31-23-15-7) 52-40-32-24-16-8) 70-64-90-88-62-68-94-112-96 (72-66-92 (108 (88) 112) 110 (100) 116 (90) 114) 120 (133) 127 (118 (94) 131) 80 (47-35-27-19-11-3) 48-36-28-20-12-4 / h41-44, 53-76, 79-82H, 9-40, 45-52H2, 1-8H3. FYQVTINZMWVMSE-UHFFFAOYSA-N. Alfa Chemistry Materials 4
Sfr274 I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (Hind III-digest) in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 2000U; 10000U. C↑TCGAG GAGCT↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Streptomyces fradiae 274. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1174RE. Creative Enzymes
Sfr303 I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CCGC↑GG GG↓CGCC. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Streptomyces fradiae 303. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1175RE. Creative Enzymes
sFRP-1 human recombinant, expressed in HeLa cells, ?97% (SDS-PAGE), ?97% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
sFRP-1 Inhibitor - CAS 915754-88-0 The sFRP-1 Inhibitor, also referenced under CAS 915754-88-0, controls the biological activity of sFRP-1. This small molecule/inhibitor is primarily used for Activators/Inducers applications. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
SFTI-1 SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 245080-24-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10033. MedChemExpress MCE
SFXSPO SFXSPO. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Diphenylspiro[9H-fluorene-9,9'-[9H]xanthen]-4'-ylphosphine oxide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1508022-28-3. Molecular formula: C37H25O2P. Mole weight: 532.57 g/mol. Product ID: ACM1508022283. Alfa Chemistry — ISO 9001:2015 Certified. Categories: SFX (software). Alfa Chemistry. 2
SG-094 SG-094 is a potent TPC2 inhibitor with antiproliferative effects. SG-094 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922283-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148816. MedChemExpress MCE
SG2057 SG2057 is a pentyldioxy linked PBD dimer which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts, and also mono-adducts depending on sequence. SG2057 has multilog differential in vitro cytotoxicity against a panel of human tumour cell lines with a mean GI(50) of 212 pM. The agent is highly efficient at producing DNA interstrand cross-links in cells which form rapidly and persist over a 48h period. Cures were obtained in a LOX-IMVI melanoma model following a single administration and dose-dependent activity, including regression responses, observed in SKOV-3 ovarian and HL-60 promyelocytic leukemia models following repeat dose schedules. In the advanced stage LS174T model, SG2057 administered either as a single dose, or in two repeat dose schedules, was superior to irinotecan. SG2057 is therefore a highly active antitumor agent, with more potent in vitro activity and superior in vivo activity to SG2000. Synonyms: SG-2057; SG 2057; DRG-16; (11aS,11a'S)-8,8'-(pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methylene-2,3-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5(11aH)-one). CAS No. 260417-62-7. Molecular formula: C33H36N4O6. Mole weight: 584.66. BOC Sciences 2
SG-209 solid, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
SG3199 SG3199 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1595275-71-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101161. MedChemExpress MCE
SGA360 SGA360. Group: Biochemicals. Alternative Names: 3-(2,4-Dimethoxyphenyl)-1-(2-propen-1-yl)-7-(trifluoromethyl)-1H-indazole; 1-Allyl-3-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)-1H-indazole. Grades: Highly Purified. CAS No. 680611-86-3. Pack Sizes: 10mg. Molecular Formula: C19H17F3N2O2, Molecular Weight: 362.35. US Biological Life Sciences. USBiological 3
Worldwide
SGA360-d5 SGA360-d5. Group: Biochemicals. Alternative Names: 3-(2,4-Dimethoxyphenyl)-1-(2-propen-1-yl)-7-(trifluoromethyl)-1H-indazol-d5; 1-Allyl-3-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)-1H-indazole-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H12D5F3N2O2, Molecular Weight: 367.38. US Biological Life Sciences. USBiological 3
Worldwide
S-(γ)-Phe S-(γ)-Phe. Synonyms: S gamma Phe. CAS No. 916198-97-5. Molecular formula: C11H15NO2. Mole weight: 193.24. BOC Sciences 11
SGC0946 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
SGC0946 SGC0946 is a selective DOT1L H3K79 methyltransferase ) inhibitor, with an IC 50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1561178-17-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15650. MedChemExpress MCE
SGC0946 SGC0946 Inhibitor. Uses: Scientific use. Product Category: T3082. CAS No. 1561178-17-3. TARGETMOL CHEMICALS
SGC-0946 SGC-0946. Group: Biochemicals. Alternative Names: 1- (3- ( ( ( (2R, 3S, 4R, 5R) -5- (4-Amino-5-bromo-7H-pyrrolo [2, 3-d] pyrimidin-7-yl) -3, 4-di hydroxytetra hydrofuran-2-yl) methyl ) (isopropyl ) amino) propyl ) -3- (4- (tert-butyl) phenyl) urea. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C28H40BrN7O4, Molecular Weight: 618.57. US Biological Life Sciences. USBiological 3
Worldwide
SGC 0946 (1- [3- [ [ [ (2R, 3S, 4R, 5R) -5- (4-Amino-5-­bromo-7H-pyrrolo [2, 3-d] pyrimidin-7-yl) -3, 4-di hydro­xytetra hydrofuran-2-yl] methyl ] (isopropyl ) amino] pro­pyl] -3- [4- (2, 2-di methyl ethyl) phenyl] urea) Potent DOT1L methyltransferase inhibitor (KD = 0.06nm, IC50 = 0.3nm in a radioactive assay); blocks H3K79 methylation in A431 cells and MCF10A cells (IC50 values are 2.65 and 8.8nm respectively). Inactive at 12 histone methyltransferases and DNMT1. Selectively kills cells transformed with the MLL-AF9 fusion oncogene in an in vitro model of leukemia; lowers levels of MLL target genes HOXA9 and Meis1. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
SGC2085 SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 ( CARM1 ) with an IC 50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC 50 value of 5.2 μM, but not other PRMT proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1821908-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100565. MedChemExpress MCE
SGC3027 SGC3027 is a histone methyltransferase inhibitor[1]. SGC3027 is the first potent, selective and cell active chemical probe for PRMT7[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2624313-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112445. MedChemExpress MCE

Would you like to list your products on USA Chemical Suppliers?

Our database is helping our users find suppliers everyday.

Add Your Products