A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
SGC-AAK1-1 is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC 50 of 270 nM and a K i of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247894-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123940.
SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613695-14-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15826.
SGC-CK2-1 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC 50 s of 36 and 16 nM for CK2α and CK2αrespectively in the nanoBRET assay. SGC-CK2-1 can be used for the research of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470424-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139004.
SGC-GAK-1 is a potent, selective cyclin G-associated kinase (GAK) inhibitor with a Ki of 3.1 nM. SGC-GAK-1 is a chemical probe for GAK[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226517-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122186.
SGC-STK17B-1 is an ATP-competitive and selective STK17B (a member of DAPK family) inhibitor ( IC 50 : 34 nM, K D : 5.6 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2650530-00-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156350.
SGD-1882
SGD-1882 is a cytotoxic, DNA minor-groove crosslinking agent pyrrolobenzodiazepine (PBD) dimer, acting as the payload for ADCs. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PBD dimer. CAS No. 1222490-34-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101127.
SGD-1910
SGD-1910 is a agent-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1342820-51-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101162.
SGF29-IN-1
SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)-associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6638-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158009.
SGI 1027
SGI 1027. Group: Biochemicals. Grades: Purified. CAS No. 1020149-73-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SGI-1027
SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 ?M, 8 ?M, and 12.5 ?M for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate. Uses: Scientific research. Group: Signaling pathways. CAS No. 1020149-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13962.
SGI-1776 free base is an inhibitor of Pim kinases, with IC 50 s of 7 nM, 363 nM, and 69 nM for Pim-1, -2 and -3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1025065-69-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13287.
SgI-29
SgI-29 is an antibacterial peptide isolated from Homo sapiens. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: SgI-29 (85-113); His-Asn-Lys-Gln-Glu-Gly-Arg-Asp-His-Asp-Lys-Ser-Lys-Gly-His-Phe-His-Arg-Val-Val-Ile-His-His-Lys-Gly-Gly-Lys-Ala-His. Grade: >97%. Molecular formula: C145H226N56O39. Mole weight: 3377.74.
SgII peptide A is an antibacterial peptide isolated from Homo sapiens. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: SgII peptide A (human); Lys-Gln-Glu-Gly-Arg-Asp-His-Asp-Lys-Ser-Lys-Gly-His-Phe-His-Met-Ile-Val-Ile-His-His-Lys-Gly-Gly-Gln-Ala-His-His-Gly. Grade: >97%. Molecular formula: C142H218N52O39S. Mole weight: 3309.68.
SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1279829-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18607.
SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter ( SGLT2 ), with IC 50 of 33 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864070-37-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-I1120.
S-(+)-Glycidyl tosylate
S-(+)-Glycidyl tosylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 70987-78-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
SGN-2FF
SGN-2FF is a potent and orally active inhibitor of fucosylation, directly inhibits fucosyltransferase activity. SGN-2FF possesses antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089647-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107366.
SGN-B6A
SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug (HY-P990764), and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164957.
sGnRH-A
sGnRH-A is a GnRH peptide analog that acts as a GnRH antagonist. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Arg-Trp-Leu-Pro-NHEt. CAS No. 96497-82-4. Molecular formula: C64H83N17O12. Mole weight: 1282.45.
sGnRH-A TFA
sGnRH-A is a GnRH peptide analog that acts as a GnRH antagonist. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Arg-Trp-Leu-Pro-NHEt.CH3CO2H; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-arginyl-L-tryptophyl-L-leucyl-L-proline ethylamide acetic acid. Molecular formula: C66H87N17O14. Mole weight: 1342.53.
sgp91 ds-tat Peptide 2, scrambled
sgp91 ds-tat Peptide 2, scrambled is a scrambled sequence of NADPH oxidase inhibitor gp91 ds-tat peptide. It is used as a control peptide. Molecular formula: C98H190N50O22S. Mole weight: 2453.
SGR-1505
SGR-1505 is an orally active MALT1 allosteric inhibitor. SGR-1505 inhibits MALT1 enzymatic activity and shows anti-proliferative activity in BTK inhibitor (BTKi)-sensitive and BTKi-resistant activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines. SGR-1505 can be used for research of B-cell lymphomas [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2661481-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160698.
sgRNA Screening Kit
sgRNA Screening Kit. Sgrna screening kit provides a simple, reliable, and rapid method for assessing sgrna efficiency before cell transduction, allowing you to identify the highly effective crispr sgrna. cas9 nuclease nls is an rna-guided endonuclease that catalyzes site-specific cleavage of double stranded dna. the location of the break is within the target sequence 3 bases from the ngg pam (protospacer adjacent motif). the design of single guide rna (sgrna) is dependent on the target region close to the pam site. even if you pick a target sequence that fulfills all of the described requirements, sgrna specificity and activity is unpredictable. therefore, it is often recommended that multiple, different sgrnas be designed to target a gene of interest. components. gencrispr cas9 nuclease. 10x reaction buffer. positive control sgrna. positive control substrate. rnase-free water. Group: Cloning Enzymes. Purity: 30 reactions/kit. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol PH 7.4, at 25°C. Cat No: CE-3509.
sgRNA Synthesis Kit
sgRNA Synthesis Kit. This product is designed to synthesize grnas in vitro. in the bacterial crispr/cas9 system, the cas9 nuclease associates with two rnas, the crispr rna (crrna) and the trans-activating crrna (tracrrna), to direct sequence-specific dna cleavage. the grna (guide rna) is a fusion of the natural crrna and tracrrna components. it contains an 18-20 base variable sequence that can be changed to target any dna sequence that is adjacent to an ngg proto-spacer adjacent motif (pam) on the 3 end of the target sequence. the sgrna synthesis kit allows user to fuse their choice of 18-20 base target sequence within the grna dna sequence provided, by pcr fusion. the kit also provides materials for in-vitro transcription of the generated grna dna in order to generate grnas which can be directly used for in-vivo genome editing. Group: Cloning Enzymes. Purity: 20 reactions/kit. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol PH 7.4, at 25°C. Cat No: CE-3510.
Sgs 518 oxalate
Sgs 518 oxalate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SGS 518 oxalate, CTK8E8444, 445441-27-0. Product Category: Heterocyclic Organic Compound. CAS No. 445441-27-0. Molecular formula: C21H22F2N2O3S.C2H2O4. Purity: >98 %. IUPACName: [1-methyl-3-(1-methylpiperidin-4-yl)indol-5-yl] 2,6-difluorobenzenesulfonate;oxaldehydic acid. Canonical SMILES: CN1CCC(CC1)C2=CN(C3=C2C=C(C=C3)OS(=O)(=O)C4=C(C=CC=C4F)F)C.C(=O)C(=O)O. Product ID: ACM445441270. Alfa Chemistry ISO 9001:2015 Certified.
SGS 518 oxalate
SGS 518 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 445441-27-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SGX 523
SGX 523. Group: Biochemicals. Grades: Purified. CAS No. 1022150-57-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SGX-523
SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1022150-57-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12019.
SH-42
SH-42 is a potent and selective inhibitor of human ?24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143952-36-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143228.
SH-4-54
SH-4-54 is a STAT inhibitor that binds to STAT3 and STAT5 with KDs of 300, 464 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1456632-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16975.
SH514
SH514 is an interferon regulatory factor 4 (IRF4) inhibitor with an IC50 value of 2.63 ?M. SH514 can be bound to the IRF4-DBD domain with KD values of 1.28 ?M. SH514 can be used to study multiple myeloma (MM)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172085.
A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt. Group: Biochemicals. Alternative Names: D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt. Group: Biochemicals. Alternative Names: D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
SHA 68
SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50s of 22.0 and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 847553-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108625.
SHA 68. Group: Biochemicals. Grades: Purified. CAS No. 847553-89-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Shaddock powder
Shaddock powder. Group: Others. Source: Shaddock (scientific name: Citrus maxima), also known as pomelo, Hong Luan, grapefruit, purple inside. Shaddock powder fragrance, sweet, cool moist, nutrient-rich, high medicinal value, is one of the people eating the fruit, but also the medical profession recognized the fruit of the most therapeutic effect. Grapefruit and grapefruit peel tea also has practical value, and can be used as medicine. Shaddock powder. Cat No: EXTC-146.
SHANK 1, CT, Control Peptide (Postsynaptic Density Protein)
Control Peptide for S1010-88A1 SHANK 1, CT. Group: Molecular Biology. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
shanzhiside
shanzhiside. Group: Biochemicals. Grades: Plant Grade. CAS No. 29836-27-9. Pack Sizes: 10mg. Molecular Formula: C16H24O11, Molecular Weight: 392.36. US Biological Life Sciences.
Worldwide
Shanzhiside methylester
Shanzhiside methylester. Group: Biochemicals. Grades: Plant Grade. CAS No. 64421-28-9. Pack Sizes: 20mg. Molecular Formula: C17H26O11, Molecular Weight: 406.38. US Biological Life Sciences.
Worldwide
Shanzhiside methyl ester
Shanzhiside methyl ester. Group: Biochemicals. CAS No. 64421-28-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Shanzhiside methyl ester
Shanzhiside methy lester is isolated from lamiophlomis rotata. Shanzhiside methyl ester is a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist and has the ability to induce anti-allodynic tolerance [1]. Uses: Scientific research. Group: Natural products. CAS No. 64421-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0630.
SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1841409-92-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124758.
Shea butter
It is ivory in color when raw and commonly dyed yellow with borututu root or palm oil. Product ID: CDC10-0489. Category: Moisturizers. Product Keywords: Cosmetic Ingredients; Moisturizers; Shea butter; CDC10-0489. Application: Shea butter is mainly used in the cosmetics industry for skin- and hair-related products (lip gloss, lip stick, skin moisturizer creams and emulsions, and hair conditioners for dry and brittle hair).
Sheep placenta extract
Sheep placenta extract. Applications: Cosmetic field, pharmaceutical field, food product field, health care product field. Group: Others. Purity: 70% -80% protein. Appearance: Gray fine powder. Source: Sheep placenta is a rich source of nutrients, growth factors and bio-active cytokines. It is based on these bio-essentials that new life is developed. Scientific studies found that placenta contains high level of special proteins (placenta proteins), some of them promote cell growth, some of them regulate hormone secretion and some of them strengthen our immune system. Sheep placenta extract. Cat No: EXTC-201.
Sheep Placenta P.E. 20:1 (China & NZ Material)
Sheep Placenta P.E. 20:1 (China & NZ Material).
CA, FL & NJ
Shellac
Shellac. Synonyms: Shellac Flake;(5ξ,10β)-10,14-Dihydroxycedr-8-ene-12,15-dioic acid - 9,10,15-trihydroxypentadecanoic acid (1:1);SHELLAC GUM, ORANGE;SHELLAC ORANGE;Shellac;SHELLAC WAX-FREE, PH EUR;SHELLAC ORANGE BEST QUALITY;Schellack. CAS No. 9000-59-3. Pack Sizes: 1 kg. Product ID: CDF4-0015. Category: Coating Agents. Product Keywords: Food Ingredients; Coating Agents; Shellac; CDF4-0015; 9000-59-3; 232-549-9; 9000-59-3. Purity: 0.99. EC Number: 232-549-9. Solubility: Practically insoluble in water, gives a more or less opalescent solution (wax containing shellac and bleached shellac) or a clear solution (dewaxed shellac and bleached, dewaxed shellac) in anhydrous ethanol. When warmed it is sparingly soluble or soluble in alkaline solutions. Storage: 2-8°C. Application: Shellac is used in the preparation of cosmetic products such as mascara and acrylic nail products. It is also used in the formulation of aqueous-core capsules for riboflavin release. Melting Point: 115-120°. Density: 1.035-1.140.
Shellac
Shellac. Synonyms: Shellac Flake;(5ξ,10β)-10,14-Dihydroxycedr-8-ene-12,15-dioic acid - 9,10,15-trihydroxypentadecanoic acid (1:1);SHELLAC GUM, ORANGE;SHELLAC ORANGE;Shellac;SHELLAC WAX-FREE, PH EUR;SHELLAC ORANGE BEST QUALITY;Schellack. CAS No. 9000-59-3. Product ID: PE-0200. Category: Coating Systems Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Coating Systems Excipients; Shellac; PE-0200; 9000-59-3; 9000-59-3. Purity: 0.99. EC Number: 232-549-9. Solubility: Practically insoluble in water, gives a more or less opalescent solution (wax containing shellac and bleached shellac) or a clear solution (dewaxed shellac and bleached, dewaxed shellac) in anhydrous ethanol. When warmed it is sparingly soluble or soluble in alkaline solutions. Storage: 2-8°C. Application: Shellac is used in the preparation of cosmetic products such as mascara and acrylic nail products. It is also used in the formulation of aqueous-core capsules for riboflavin release. Melting Point: 115-120°. Density: 1.035-1.140.
Shellac 9000-59-3
Shellac - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
Shepherdin 79-87 is amino acids 79 to 87 fragment of Shepherdin. Shepherdin makes extensive contacts with the ATP pocket of Hsp90, destabilizes its client proteins, and induces massive death of tumor cells by apoptotic and nonapoptotic mechanisms. Conversely, shepherdin does not reduce the viability of normal cells nor affect colony formation of purified hematopoietic progenitors. Systemic administration of shepherdin in vivo is well tolerated, and inhibits human tumor growth in mice without toxicity. Synonyms: NSC-741765; L-Lysyl-L-histidyl-L-seryl-L-serylglycyl-L-cysteinyl-L-alanyl-L-phenylalanyl-3-methyl-L-valine. Grade: >98%. CAS No. 861224-28-4. Molecular formula: C41H64N12O12S. Mole weight: 949.09.
Shepherin I
Shepherin I is an antibacterial peptide isolated from Capsella bursa-pastoris. It has activity against gram-negative bacteria and fungi. Synonyms: Gly-Tyr-Gly-Gly-His-Gly-Gly-His-Gly-Gly-His-Gly-Gly-His-Gly-Gly-His-Gly-Gly-His-Gly-His-Gly-Gly-Gly-Gly-His-Gly. Grade: >96%. Molecular formula: C95H124N44O30. Mole weight: 2362.31.