A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Silwet - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Silybin
mixture of Silybin A and B, primary reference standard. Group: Chemical class.
Silybin
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Silybin
Hepatoprotectant. In nature, the flavonolignan Silybin occurs as a mixture of two diastereomers, Silybin A and Silybin B. Group: Biochemicals. Alternative Names: (2R,3R)-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 802918-57-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Silybin
Silybin is a flavonolignan isolated from milk thistle ( Silybum marianum ) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Silibinin. CAS No. 802918-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0779A.
Silybin A
Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Synonyms: Silybin; 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-; (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trih
Silybin A
Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Uses: Scientific research. Group: Natural products. Alternative Names: Silibinin A. CAS No. 22888-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13748.
Silybin B
analytical standard. Group: Chemical class.
Silybin(Mixture A&B)
Silybin(Mixture A&B). Group: Biochemicals. Alternative Names: Silibinin; Silymarin. Grades: Plant Grade. CAS No. 22888-70-6. Pack Sizes: 20mg. Molecular Formula: C25H22O10, Molecular Weight: 482.435999999999. US Biological Life Sciences.
Silybum marianum Seed oil microencapsulated powder. Product ID: CDF4-0211. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0211; Silybum marianum Seed oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: Silybum marianum Seed. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc.
Silychristin
analytical standard. Group: Natural compounds.
Silychristin
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum , with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8 , and elicits a strong inhibition of T3 uptake with an IC 50 of 110 nM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 33889-69-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0647.
Silydianin is an active constituent of Silybium marianum , with exhibit anti-collagenase, antitumor and anti-elastase activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) with an IC 50 of 17.38?μM. Silydianin has inhibitory effect on the in vitro production and release of oxidative products [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 29782-68-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0646.
for GC derivatization. Group: Derivatization reagents gc.
Silylating mixture III
for GC derivatization. Group: Derivatization reagents gc.
Silyl Modified Polymer (SMP) MS Polymer Hybrid Polymers
Silyl Modified Polymer (SMP) MS Polymer Hybrid Polymers. Group: Copolymers.
Silymarin
Silymarin. Group: Biochemicals. Alternative Names: Apihepar; Darsil; Flavobion; Karsilin; Laragon; Legalon; Legalon 70; Pluropon; Silarin; Silepar; Silirex; Silistrong; Silmar; Silymarin Group; Silystrong. Grades: Highly Purified. CAS No. 65666-07-1. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Silymarin
25g Pack Size. Group: Bioactive Small Molecules, Organics, Research Organics & Inorganics. Formula: C25H22O10. CAS No. 22888-70-6. Prepack ID 17270291-25g. Molecular Weight 482.44. See USA prepack pricing.
Silymarin
5g Pack Size. Group: Bioactive Small Molecules, Organics, Research Organics & Inorganics. Formula: C25H22O10. CAS No. 22888-70-6. Prepack ID 17270291-5g. Molecular Weight 482.44. See USA prepack pricing.
Silymarin
Silymarin is an extract of the milk thistle ( Silybum marianum ). Silymarin is an effective SARS-CoV-2 main protease (M pro ) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC). Silymarin has the potential for COVID-19 research [1] [2] [4]. Uses: Scientific research. Group: Natural products. CAS No. 65666-07-1. Pack Sizes: 250 mg; 500 mg. Product ID: HY-N7073.
Silymarine
Silymarine. Group: Biochemicals. Alternative Names: Silymarin I; 2-[2R,3R-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2R,3R-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 22888-70-6,36804-17-8,65666-07-1,802918-57-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C25H22O10. US Biological Life Sciences.
Worldwide
SIM1
SIM1 is a potent von Hippel-Lindau (VHL)-based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation (IC50=1.1 nM; Kd=186 nM). SIM1 shows sustained anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2719051-84-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141438.
Simazine
Simazine is a triazine herbicide widely used in agriculture, pot-plant and tree production. Simazine is phytotoxicity and not highly toxic to soil microflora and algae [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122-34-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B2046.
Simazine
Selective pre-emergence herbicide. Group: Biochemicals. Alternative Names: 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine;2-Chloro-4,6-bis(ethylamino)-s-triazine; 2,4-Bis(ethylamino)-6-chloro-s-triazine; 2,4-Di(ethylamino)-6-chloro-1,3,5-triazine; 2-Chloro-4,6-bis(ethylamino)-1,3,5-triazine;Aktinit S; Aquazine; Azotop; Batazina FLO; Bitemol S 50; Gesatop; Premazine; Princep; Radocon; Radokor; Simanex; Symazine; Tafazine; Taphazine; Triazine A 384; W 6658; Yrodazin. Grades: Highly Purified. CAS No. 122-34-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Simazine-13C5
Simazine-13C5 is the isotope labelled analog of Simazine (S465900); a selective pre-emergence herbicide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C213C5H12ClN5, Molecular Weight: 206.62. US Biological Life Sciences.
Worldwide
Simazine-d10
analytical standard. Group: Chemical classpesticides & metabolitespharma & vet compounds & metabolitesstable isotope labelled compoundspesticides & metabolitespharma & vet compounds & metabolitesstable isotope labelled compounds. Alternative Names: Simazine D10.
Simazine-[d10]
Simazine-[d10] is the labelled analogue of Simazine. Simazine is an herbicide used for control of broad-leaved weeds and annual grasses. Synonyms: Simazine D10; 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine-d10; 2-Chloro-4,6-bis(ethylamino)-s-triazine-d10. Grade: 95% by HPLC; 98% atom D. CAS No. 220621-39-6. Molecular formula: C7H2D10ClN5. Mole weight: 211.72.
Simazine-[d5]
Simazine-[d5]. Synonyms: Simazine D5 (ethyl D5); 6-Chlor-N-ethyl-N'-(2H5)ethyl-1,3,5-triazin-2,4-diamin. Grade: 95% atom D. CAS No. 220621-41-0. Molecular formula: C7H7D5ClN5. Mole weight: 206.69.
SiMCP2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis[3,5-di(9H -carbazol-9-yl)phenyl]diphenylsilane. Product Category: Organic Light Emitting Diode (OLED). CAS No. 944465-42-3. Molecular formula: C72H48N4Si. Mole weight: 977.26 g/mol. Product ID: ACM944465423. Alfa Chemistry ISO 9001:2015 Certified. Categories: bis[3,5-di(9h-carbazol-9-yl)phenyl]diphenylsilane.
Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a K i of 0.36 nM. Simeprevir inhibits HCV replication with an EC 50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M pro ) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC435; TMC435350. CAS No. 923604-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10241.
Simethicone
Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8050-81-5. Pack Sizes: 1 g; 5 g; 10 g; 50 g. Product ID: HY-109519.
Simethicone
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Simetryn. Group: Biochemicals. Alternative Names: 2,4-Bis(ethylamino)-6-methylmercapto-s-triazine; 2,4-Bis(ethylamino)-6-methylthio-1,3,5-triazine; 2,4-Diethylamino-6-methylthio-1,3,5-triazine; 2-Methylmercapto-4,6-bis(ethylamino)-s-triazine; 2-Methylthio-4,6-bis(ethylamino)-1,3,5-triazine; 2-Methylthio-4,6-bis(ethylamino)-s-triazine; 2-Methylthio-4-ethylamino-6-ethylamino-s-triazine; 4,6-Bis(ethylamino)-2-methylthio-1,3,5-triazine; 6-Methylthio-2,4-bis(ethylamino)-s-triazine; G 32911; Gybon; N,N'-Diethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine; N2,N4-Diethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine; NSC 163051; Simetryne; 2,4-Bis(ethylamino)-6-(methylthio)-s-triazine; N,N'-Diethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine; N2,N4-Diethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine. Grades: Highly Purified. CAS No. 1014-70-6. Pack Sizes: 1g. Molecular Formula: C8H15N5S, Molecular Weight: 213.3. US Biological Life Sciences.
Worldwide
Simetryn
Simetryn is a herbicide with an IC50 value of 16.9-3.70 mg/L (79.3-17.4 microM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1014-70-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1853.
Simlukafusp alfa
Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α ( FAPα ) and an IL-2 variant that only binds IL-2Rβ&gamma. Isotype: human IgG1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FAP-IL2v. CAS No. 1776942-10-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P99902.
SIMMONDSIN
SIMMONDSIN. Uses: Designed for use in research and industrial production. Appearance: White powder. CAS No. 51771-52-9. Molecular formula: C16H25NO9. Mole weight: 375.38. Purity: 0.999. Product ID: ACM51771529. Alfa Chemistry ISO 9001:2015 Certified.
Simnotrelvir
SARS-CoV-2-IN-41 (compound 2) is a potent SARS-CoV-2 3CL pro inhibitor with an IC 50 value of 0.022 μM. SARS-CoV-2-IN-41 shows antiviral effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIM0417; SARS-CoV-2-IN-41. CAS No. 2920904-06-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154965.
Simocyclinone D4
It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.30, 5.6 and 8.5, respectively. Molecular formula: C46H43NO18. Mole weight: 897.83.
Simocyclinone D8
Antibiotic. Bacterial DNA gyrase inhibitor: Staphylococcus aureus (IC50=1.45uM), E. coli (IC50=0.41uM). Human topoisomerase II (Topo II) inhibitor (IC50=100uM). Antibacterial (Gram-positive). Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 301845-97-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Simocyclinone D8
It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.50, 0.95 and >50, respectively. Synonyms: 9-[4-O-Acetyl-3-O-[10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]-1,10-dioxo-2,4,6,8-decatetraenyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]-4a,5,6,12b-tetrahydro-4a,6,7,8,12b-pentahydroxy-3-methyl-6a,12a-epoxybenz[a]anthracene-1,12(4H,7H)-dione; (1R)-4-O-acetyl-1,5-anhydro-3-O-{(2E,4E,6E,8E)-10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-chromen-3-yl)amino]-10-oxodeca-2,4,6,8-tetraenoyl}-2,6-dideoxy-1-[(4aR,6S,6aS,7S,12aS,12bR)-4a,6,7,8,12b-pentahydroxy-3-methyl-1,12-dioxo-1,4,4a,5,6,7,12,12b-octahydro-6a,12a-epoxytetraphen-9-yl]-D-arabino-hexitol. Grade: ≥95%. CAS No. 301845-97-6. Molecular formula: C46H42ClNO18. Mole weight: 932.27.
Simonyellin
Simonyellin is a naphthopyran from the lichen Simonyella variegata Steiner. CAS No. 173322-91-3. Molecular formula: C14H10O6. Mole weight: 274.23.
SI Moricin
SI Moricin is an antibacterial peptide isolated from Spodoptera litura (Lepidopteran insect). It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: S. litura moricin; Gly-Lys-Ile-Pro-Val-Lys-Ala-Ile-Lys-Lys-Ala-Gly-Ala-Ala-Ile-Gly-Lys-Gly-Leu-Arg-Ala-Ile-Asn-Ile-Ala-Ser-Thr-Ala-His-Asp-Val-Tyr-Ser-Phe-Phe-Lys-Pro-Lys-His-Lys-Lys-Lys. Molecular formula: C208H348N60O50. Mole weight: 4489.42.
Simple Nutrients - WP
Proficiency Testing Material, Concentrate for dilution to 1 L. Group: Waste water.
Simtuzumab
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 ( LOXL2 ). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AB 0024; GS 6624. CAS No. 1318075-13-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99047.
Simufilam
Simufilam (PTI-125), a compound, can be uesd for screening of agent candidate. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTI-125. CAS No. 1224591-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-139142.
Simufilam hydrochloride
Simufilam (PTI-125) hydrochloride, a compound, can be uesd for screening of agent candidate. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTI-125 hydrochloride. CAS No. 2480226-07-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139142B.
Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of <0.3 nM. Simurosertib has anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-931. CAS No. 1330782-76-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100888.
Simvastatin
Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a K i of 0.2 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 733. CAS No. 79902-63-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17502.
Simvastatin
Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM. Synonyms: Nodinitib-1; Zocor; Synvinolin; MK-733; Sinvacor; MK 733; MK733. Grade: >98%. CAS No. 79902-63-9. Molecular formula: C25H38O5. Mole weight: 418.57.
Simvastatin
A competitive inhibitor of HMG-CoA reductase. A synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin; Cholestat; Lipex; Novo-Simvastatin; Simvotin; Sinvacor; Statin; Zorced; MK-733, Synvinolin, BRN 4768037; Zocor, Liponorm. Grades: Highly Purified. CAS No. 79902-63-9. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C??H??O?, Molecular Weight: 418.57. US Biological Life Sciences.
Worldwide
Simvastatin, 1-pyreneacetyl ester
Simvastatin, 1-pyreneacetyl ester. Group: Biochemicals. Alternative Names: [1S-[1a(b-S*, δS*), 2a, 6b, 8b, 8a-a]]-1-pyreneacetic acid, anhydride with 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic acid. Grades: Highly Purified. CAS No. 193682-18-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C43H50O7. US Biological Life Sciences.
Worldwide
Simvastatin 4'-methyl ether
Simvastatin 4'-methyl ether. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-butanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; Cholestat methyl ether. Grades: Highly Purified. CAS No. 864357-88-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H40O5. US Biological Life Sciences.
Worldwide
Simvastatin 4'-Methyl Ether
Simvastatin 4'-Methyl Ether. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl 2,2-dimethylbutanoate,Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-Methoxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate. CAS No. 864357-88-0. IUPAC Name: [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-methoxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate. Molecular formula: C26H40O5. Mole weight: 432.59. Catalog: APS864357880. SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)O3)OC)[C@@H]12. Format: Neat.
Simvastatin acid ammonium
Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Tenivastatin ammonium. CAS No. 139893-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119695A.
Simvastatin Acyl-β-D-glucuronide
A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Uses: The treatment of acute hyperammonemia. Synonyms: Simvastatin Acyl-beta-D-glucuronide; 1-[(βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoate] β-D-Glucopyranuronic Acid. Grade: > 95%. CAS No. 463962-56-3. Molecular formula: C31H48O12. Mole weight: 612.71.
Simvastatin Acyltransferase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E. coli. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.x. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Simvastatin Acyltransferase. Pack: 100ml. Cat No: NATE-1811.
Simvastatin-[d11]
An isotope labelled of Simvastatin. Simvastatin is a lipid-lowering medication as a competitive inhibitor of HMG-CoA reductase. Synonyms: Simvastatin-d11 (2,2-dimethylbutyrate-d11). Grade: 95% by HPLC; 98% atom D. CAS No. 1002347-74-1. Molecular formula: C25H27D11O5. Mole weight: 429.64.
Simvastatin-[d3]
An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Synonyms: Simvastatin D3 lactone. Grade: 95% by HPLC; 98% atom D. CAS No. 1002347-61-6. Molecular formula: C25H35D3O5. Mole weight: 421.58.
Simvastatin-d6
Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A deuterated synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6. Grades: Highly Purified. CAS No. 1002347-71-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C??H??D?O?, Molecular Weight: 424.6. US Biological Life Sciences.
Worldwide
Simvastatin-[d6]
An isotope labelled Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro -3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl] -1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6. Grade: >95%. CAS No. 1002347-71-8. Molecular formula: C25H32D6O5. Mole weight: 424.61.