Acetate Kinase Suppliers USA
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Product | Description | |
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Protein Kinase C 19-31 acetate Quick inquiry Where to buy Suppliers range | Protein Kinase C 19-31 acetate is a peptide inhibitor of protein kinase C (PKC) originating in the pseudo-substrate regulatory domain of PKCA (residues 19-31). It is used as a protein kinase C substrate peptide for testing the protein kinase C activity. Synonyms: PKC (19-31) acetate; H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH.CH3CO2H; L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine acetic acid. Grades: ≥95%. Molecular formula: C69H122N26O18. Mole weight: 1603.90. | |
Protein Kinase C Peptide Substrate acetate Quick inquiry Where to buy Suppliers range | Protein Kinase C Peptide Substrate acetate targets specific cell compartments and activates G protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors by relying on second messenger and specific adaptor proteins in response to extracellular signals. It regulates a variety of physiological functions, including nervous, endocrine, exocrine, inflammatory, and immune system activation. Synonyms: L-α-Glutamyl-L-arginyl-L-methionyl-L-arginyl-L-prolyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-seryl-L-valyl-L-arginyl-L-arginyl-L-arginyl-L-valine acetate; H-Glu-Arg-Met-Arg-Pro-Arg-Lys-Arg-Gln-Gly-Ser-Val-Arg-Arg-Arg-Val-OH acetate. Grades: ≥95%. Molecular formula: C85H159N39O23S. Mole weight: 2127.52. | |
Nur77 LBD Antagonist, TMPA (AMPK Signaling Activator XII, Liver Kinase B Activator, LKB1 Activator, MARK Signaling Activator, STK11 Activator, TR3 LBD Antagonist, Ethyl-2- (2, 3, 4-trimethoxy-6- (1-octanoyl) phenyl) acetate) Quick inquiry Where to buy Suppliers range | A cell-permeable phenylacetate compound that blocks Nur77 (TR3) LKB1 nuclear-sequestering function by antagonizing against Nur77-LKB1 interaction via direct binding at the LKB1 LBD/ligand binding domain (Kd = 0.14 against 5uM LKB1 binding to 5uM full-length Nur77). Shown to induce LKB1 Ser428 phosphorylation (10 & 20uM for 6h) and LKB1 nuclear-to-cytosol translocation in hepatic LO2 cells, resulting in enhanced phosphorylations of LKB1 cytosolic effectors AMPKalpha and MARK1/2/3 without affecting Nur77 transactivation activity. Daily i.p. dosing (50mg/kg) is shown to increase liver LKB1 Ser428/AMPKalpha Thr172 phosphorylations in diabetic db/db mice in vivo, effectively improving animal glucose tolerance. Also reported to lower fasting blood glucose level in STZ-treated, high fat diet-fed type II diabetic mice. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
1,1-Dimethoxy-N,N-dimethylmethanamine Quick inquiry Where to buy Suppliers range | 1,1-Dimethoxy-N,N-dimethylmethanamine is used as a reagent in the formation of pyridine derivatives that exhibit inhibition against PI3 kinase p110α enzymes. Group: Biochemicals. Alternative Names: 1,1-Dimethoxy-trimethylamine; (Dimethoxymethyl) dimethylamine; (Dimethylamino) dimethoxymethane; (Dimethylamino) formaldehyde Dimethyl Acetal; 1,1-Dimethoxy-N,N-dimethylmethanamine; 1, 1-Dimethoxytri methyl amine; DMF Dimethyl Acetal; DMFDMA; Dimethoxy (dimethylamino) methane; Dimethoxy-N,N-dimethylmethanamine; Dimethoxy-N,N-dimethylmethylamine; Dimethyl Dimethylformamide Acetal; Dimethylformamide Dimethyl Acetal; Methyl-8; N, N-Dimethyl-1, 1-bis (methyloxy) methanamine; N,N-Dimethylformamide Dimethyl Acetal; N-(Dimethoxymethyl)-N,N-dimethylamine; N- (Dimethoxymethyl) dimethylamine; α , α -Dimethoxytri methyl amine. Grades: Highly Purified. CAS No. 4637-24-5. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
1,2-bis(4-methylpiperazin-1-yl)ethanone Quick inquiry Where to buy Suppliers range | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-(5CI); Nintedanib Impurity E. Grades: ≥95%. CAS No. 856843-88-4. Molecular formula: C12H24N4O. Mole weight: 240.35. | |
1,4-Diaminoanthraquinone Quick inquiry Where to buy Suppliers range | An anthraquinone derivative that is a potent and selective protein kinase CK1 delta inhibitor. Studies suggest that it has potential solar cell applications. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 proteinase. Group: Biochemicals. Alternative Names: 1,4-Diamino-9,10-anthraquinone; Acetate Red Violet R; Acetoquinone Light Heliotrope NL; Acetylon Fast Red Violet R; Akasperse Violet 3R; Amacel Heliotrope R; Cibacet Violet 2R; C.I. 61100; NSC 63807; NSC 7833; Krisolamine; Violet 14447. Grades: Highly Purified. CAS No. 128-95-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-1-oxidopyridin-3-yl)piperazine 1-oxide Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity 25. Grades: >95%. CAS No. 2488840-59-9. Molecular formula: C24H29N7O4. Mole weight: 479.54. | |
1-Acetamido-4-cyano-3-methylisoquinoline (1-Acetamido-3-methyl-4-cyanosoquinoline) Quick inquiry Where to buy Suppliers range | A selective inhibitor of cyclic AMP-dependent protein kinase (PKA). Group: Biochemicals. Alternative Names: 1-Acetamido-3-methyl-4-cyanosoquinoline. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
1-Oleoyl-2-acetyl-sn-glycerol Quick inquiry Where to buy Suppliers range | 1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. Activator of phospholipid-dependent protein kinase C and stimulator of secretion and aggregation in blood platelets. Synonyms: 18:1-2:0 DG; 1-(9Z-octadecenoyl)-2-acetoyl-sn-glycerol; DG(18:1(9Z)/2:0/0:0); OAG; 2-Acetyl-1-oleoyl-sn-glycerol; 1-O-Octadecenoyl-2-O-acetylglycerol. Grades: ≥90%. CAS No. 86390-77-4. Molecular formula: C23H42O5. Mole weight: 398.58. | |
1-Oleoyl-2-acetyl-sn-glycerol (OAG) Quick inquiry Where to buy Suppliers range | Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets. Group: Biochemicals. Alternative Names: OAG. Grades: Highly Purified. CAS No. 86390-77-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
2-((1-Acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide Quick inquiry Where to buy Suppliers range | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Benzamide, 2-[(1-acetyl-3-iodo-1H-indazol-6-yl)thio]-N-methyl-; Axitinib impurity YXA. Grades: ≥95%. CAS No. 1639138-00-3. Molecular formula: C17H14IN3O2S. Mole weight: 451.28. | |
2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide) Quick inquiry Where to buy Suppliers range | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity G. Grades: ≥95%. CAS No. 2410649-54-4. Molecular formula: C22H26N6O6. Mole weight: 470.48. | |
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosylamine Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosylamine is useful to the preparation of organo-selenium glycosides and disaccharides which target multiple kinases and are capable of inhibiting cancer progression to metastases. Synonyms: β-D-Galactopyranosylamine 2,3,4,6-Tetraacetate. Grades: 95%. CAS No. 58484-22-3. Molecular formula: C14H21NO9. Mole weight: 347.32. | |
2,3,4-Tri-O-acetyl-6-methyl- β-D-glucopyranuronosyl Genistein Glucuronide Methyl Ester Triacetate Quick inquiry Where to buy Suppliers range | 2,3,4-Tri-O-acetyl-6-methyl- β-D-glucopyranuronosyl Genistein Glucuronide Methyl Ester Triacetate is the protected metabolite of Genistein (G350000) which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C41H42O23. US Biological Life Sciences. | Worldwide |
2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 Quick inquiry Where to buy Suppliers range | 2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 is an intermediate in the synthesis of Propylene Glycol-d6 1-Glucuronide (Mixture of Diastereomers) Sodium Salt (P835237). Isotope labelled Propylene Glycol 1-Glucuronide is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H18D6O11. US Biological Life Sciences. | Worldwide |
2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid Quick inquiry Where to buy Suppliers range | 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid reduces the secretion of IL-1 β, TNF-α and IL-10 from purified murine macrophages but not of T cells; and reduces the activation of NF-κB and p38 MAP kinase pathways along with up-regulation of ERK pathways. 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid inhibits proliferation of enterobacterial antigen-reactive CD4+CD25- T cells in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 6501-72-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H11NO3, Molecular Weight: 205.21. US Biological Life Sciences. | Worldwide |
2',4'-Dichloro-2-imidazole Acetophenone Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of glycogen synthase kinase-3 (GSK-3). Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone. Grades: Highly Purified. CAS No. 252950-14-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
(2,4-Difluorophenoxy)acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | (2,4-Difluorophenoxy)acetic Acid Methyl Ester is an intermediate in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 449811-63-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H8F2O3. US Biological Life Sciences. | Worldwide |
2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Quick inquiry Where to buy Suppliers range | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: 4-Methyl-N-(4-nitrophenyl)-1-piperazineacetamide; Nintedanib Impurity F. Grades: ≥95%. CAS No. 708279-23-6. Molecular formula: C13H18N4O3. Mole weight: 278.31. | |
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64. | |
2-Acetamido-5-chloroisonicotinic Acid Quick inquiry Where to buy Suppliers range | 2-Acetamido-5-chloroisonicotinic Acid is a chemical reagent used in the synthesis of p38a protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 944390-08-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H7ClN2O3, Molecular Weight: 214.61. US Biological Life Sciences. | Worldwide |
2-Acetyl-6-methylphenol Quick inquiry Where to buy Suppliers range | 2-Acetyl-6-methylphenol is used to prepare (hydroxyphenyl) (piperidinyl)pyridines as IκB kinase β inhibitors and orally active anti-inflammatory agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 699-91-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H10O2, Molecular Weight: 150.169999999999. US Biological Life Sciences. | Worldwide |
2-Acetylamino-4-methylpyridine Quick inquiry Where to buy Suppliers range | 2-Acetylamino-4-methylpyridine is a chemical reagent used in the synthesis of potent inhibitors of Eimeria tenalla cGMP-dependant protein kinase as antiparasitic agents. Also used in the 1-pot synthesis of difluoromethyl-2-pyridone derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 5327-32-2. Pack Sizes: 5g, 25g. Molecular Formula: C8H10N2O, Molecular Weight: 150.18. US Biological Life Sciences. | Worldwide |
2-(Acetyloxy)-3-nitrobenzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 2-(Acetyloxy)-3-nitrobenzoic Acid Methyl Este is disubsituted benzoic acid derivative used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 22621-42-7. Pack Sizes: 250mg, 500mg. Molecular Formula: C10H9NO6. US Biological Life Sciences. | Worldwide |
2-chloro-N-methyl-N-(4-nitrophenyl)acetamide Quick inquiry Where to buy Suppliers range | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Acetamide, 2-chloro-N-methyl-N-(4-nitrophenyl)-; α-Chloro-N-methyl-p-nitroacetanilide; Nintedanib Impurity B. Grades: ≥95%. CAS No. 2653-16-9. Molecular formula: C9H9ClN2O3. Mole weight: 228.63. | |
2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide Quick inquiry Where to buy Suppliers range | 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide can be used as reactant/reagent for synthetic preparation of oxindole derivatives as inhibitors of tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2653-16-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9ClN2O3. US Biological Life Sciences. | Worldwide |
(2-?Chlorophenyl)?acetic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | (2-?Chlorophenyl)?acetic Acid Ethyl Ester is used to prepare clotrimazole analogs with antimalarial activities. It is also used to prepare non-nucleoside adenosine kinase inhibitors of aminoaryl aryl ethynyl pyrimidines. Group: Biochemicals. Grades: Highly Purified. CAS No. 40061-54-9. Pack Sizes: 100mg, 1g. Molecular Formula: C10H11ClO2, Molecular Weight: 198.65. US Biological Life Sciences. | Worldwide |
2-Cyano-N-(3,5-dichloro-4-methoxyphenyl)-acetamide Quick inquiry Where to buy Suppliers range | 2-Cyano-N-(3,5-dichloro-4-methoxyphenyl)-acetamide is the impurity of the drug Bosutinib (B676095), which is a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. It is related to 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile (D435380). Group: Biochemicals. Grades: Highly Purified. CAS No. 1821033-10-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H8Cl2N2O2, Molecular Weight: 259.089999999999. US Biological Life Sciences. | Worldwide |
2'-O-Acetyl-3'-azido-5'-O-benzoyl-3'-deoxyuridine Quick inquiry Where to buy Suppliers range | 2'-O-Acetyl-3'-azido-5'-O-benzoyl-3'-deoxyuridine is a highly efficacious antiviral compound extensively employed in the field of compound, manifesting its effectiveness by impeding the replication of viral DNA. The active component specifically targets viral thymidine kinase and DNA polymerase, exquisitely obstructing viral propagation. Synonyms: 1-(3'-azido-2'-O-acetyl-5'-O-benzoyl-3'-deoxy-β-D-ribofuranosyl)-uracil; ((2S,3R,4R,5R)-4-acetoxy-3-azido-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate. Grades: ≥95%. CAS No. 917239-19-1. Molecular formula: C18H17N5O7. Mole weight: 415.36. | |
3,3-Diethoxypropionitrile Quick inquiry Where to buy Suppliers range | 3,3-Diethoxypropionitrile is a propionitrile derivative used in the preparation of various biologically active compounds such as p38α mitogen-activated protein kinase inhibitors. Group: Biochemicals. Alternative Names: 3, 3-Diethoxypropane nitrile; Cyanoacetaldehyde Diethyl Acetal; Malonaldehydenitrile Diethyl Acetal. Grades: Highly Purified. CAS No. 2032-34-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
(3- (5- (4-Acetamidophenyl sulfonamido) -6-methoxypyrazin-2-yl ) propyl ) carbamate tert-Butyl Ester Quick inquiry Where to buy Suppliers range | (3- (5- (4-Acetamidophenyl sulfonamido) -6-methoxypyrazin-2-yl ) propyl ) carbamate tert-Butyl Ester is an intermediate in the synthesis of biotin-linked derivatives of Necrosulfonamide (N388600), a compound that specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
3-(Acetylamino)-2-hydroxybenzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 3-(Acetylamino)-2-hydroxybenzoic Acid Methyl Ester is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 184151-07-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H11NO4. US Biological Life Sciences. | Worldwide |
3-Acetylpyridine-5-boronic Acid Pinacol Ester Quick inquiry Where to buy Suppliers range | 3-Acetylpyridine-5-boronic Acid Pinacol Ester is a boron containing reagent used in the synthesis of pyrimidine derivitives as inhibitors of 6-phosphofructose-2-kinase used in the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1103862-13-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H18BNO3, Molecular Weight: 247.1. US Biological Life Sciences. | Worldwide |
3-(N-Acetylamino)-5-(N-decyl-N-methylamino)benzyl Alcohol Quick inquiry Where to buy Suppliers range | 3-(N-Acetylamino)-5-(N-decyl-N-methylamino)benzyl Alcohol is a synthetic protein kinase C and protein kinase A activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 103955-90-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H34N2O2, Molecular Weight: 334.5. US Biological Life Sciences. | Worldwide |
5-Acetyl-2-chloropyrazine Quick inquiry Where to buy Suppliers range | Used in the preparation of 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors. Group: Biochemicals. Alternative Names: 1-(5-Chloro-2-pyrazinyl)ethanone; 1- (5-Chloropyrazinyl) ethanone; 2-Chloro-5-acetylpyperazine. Grades: Highly Purified. CAS No. 160252-31-3. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
5-Amino-2-chlorobenzotrifluoride N-Chloroacetyl N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 5-Amino-2-chlorobenzotrifluoride N-Chloroacetyl N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50 = 83 nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R, 3R, 4S, 5S, 6S)-2- ( (4-Chloro-3- (trifluoromethyl)phenyl) (chlorocarbonyl)amino)-6- (methoxycarbonyl)tetrahydro-2H-pyran-3, 4, 5-triyl Triacetate. Molecular formula: C21H20Cl2F3NO10. Mole weight: 574.29. | |
5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R,3R,4S,5S,6S)-2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C20H21ClF3NO9. Mole weight: 511.83. | |
5'-Trifluoroacetamido-5'-deoxythymidine Quick inquiry Where to buy Suppliers range | 5'-Trifluoroacetamido-5'-deoxythymidine is an exceedingly efficacious antiviral entity, demonstrating immense potential for the research of DNA virus-mediated detrimental infections, primarily those affiliated with herpesviruses. The discerning mode of action revolves around the selective suppression of viral DNA replication through specific antagonism of viral thymidine kinase, a critical and indispensible enzyme driving viral DNA enhancement. Synonyms: 2,2,2-Trifluoro-N-(((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)acetamide; 5'-Deoxy-5'-(2,2,2-trifluoroacetamido)thymidine. Grades: 95%. CAS No. 55812-00-5. Molecular formula: C12H14F3N3O5. Mole weight: 337.26. | |
6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity 27; Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-2-amino-8-cyclopentyl-5-methyl-. CAS No. 571189-64-5. Molecular formula: C15H18N4O2. Mole weight: 286.33. | |
6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one Quick inquiry Where to buy Suppliers range | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity 26; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-. CAS No. 571189-51-0. Molecular formula: C25H31N7O2. Mole weight: 461.57. | |
Abl Cytosolic Substrate acetate Quick inquiry Where to buy Suppliers range | Abl Cytosolic Substrate acetate is a substrate for Abelson tyrosine kinase (Abl). Synonyms: Glu-Ala-Ile-Tyr-Ala-Ala-Pro-Phe-Ala-Lys-Lys-Lys acetate salt; L-α-Glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-L-Lysine acetate salt. Grades: ≥95%. CAS No. 2918768-10-0. Molecular formula: C64H101N15O16.C2H4O2. Mole weight: 1396.63. | |
Acetoacetamide Quick inquiry Where to buy Suppliers range | A building block that has been used in the preparation of glycogen synthase kinase 3 (GSK-3) inhibitors. Synonyms: 3-Oxobutanamide; 3-Oxobutyramide; Acetoacetic acid amide. Grades: > 95%. CAS No. 5977-14-0. Molecular formula: C4H7NO2. Mole weight: 101.11. | |
Acetyl-α,β-dehydro-phenylalanine Quick inquiry Where to buy Suppliers range | A protein kinase C inhibitor. Synonyms: Ac-2,3-dehydro-Phe-OH; Ac-α,β-dehydro-phenylalanine; 2-Acetamido-cinnamic acid. Grades: ≥ 96 % (HPLC). CAS No. 5469-45-4. Molecular formula: C11H11NO3. Mole weight: 205.18. | |
Acetyl-L-glutamic acid Quick inquiry Where to buy Suppliers range | A substrate for acetylglutamate kinase. An inhibitor of N-acetyl-L-glutamate synthetase. Synonyms: Ac-L-Glu-OH. Grades: 98-102% (Assay). CAS No. 1188-37-0. Molecular formula: C7H11NO5. Mole weight: 189.17. | |
Adenosine-5'-(γ-thio)-triphosphate tetralithium salt Quick inquiry Where to buy Suppliers range | Adenosine 5-[γ-thio]triphosphate Tetralithium Salt is used as a reagent in the synthesis of DNA N-acetylglucosamine analogs. Adenosine 5'-(γ-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11).1 It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs, and can serve as a substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eukaryotic initiation factor-4A. Group: Biochemicals. Alternative Names: ATP-γS; ATPγS tetralithium salt. Grades: Highly Purified. CAS No. 93839-89-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??N?O??P?SLi?, Molecular Weight: 551. US Biological Life Sciences. | Worldwide |
AdipoRon (2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide) Quick inquiry Where to buy Suppliers range | Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low um concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 924416-43-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Altenusin Quick inquiry Where to buy Suppliers range | Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grades: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27. | |
AMARA peptide acetate Quick inquiry Where to buy Suppliers range | AMARA peptide acetate is a substrate for salt-induced kinase (SIK) and adenosine monophosphate-activated protein kinase (AMPK). Molecular formula: C64H119N27O19S. Mole weight: 1602.89. | |
AMG-628 Quick inquiry Where to buy Suppliers range | AMG-628 is a highly selective, ATP-competitive inhibitor of Raf kinases. It can inhibit activation of tyrosine protein kinases. AMG-628 can also inhibit growth, and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation. Synonyms: AMG-628; AMG 628; AMG628; UNII-28J966TN3X; CHEMBL226574;N-(4-((6-(4-(1-(4-fluorophenyl)ethyl)-1-piperazinyl)-4-pyrimidinyl)oxy)-2-benzothiazolyl)-Acetamide. Grades: 98%. CAS No. 862269-73-6. Molecular formula: C25H25FN6O2S. Mole weight: 492.57. | |
Amifampridine Quick inquiry Where to buy Suppliers range | Amifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. It is used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. Uses: Neuromuscular agents. Synonyms: pyridine-3,4-diamine. Grades: > 98 %. CAS No. 54-96-6. Molecular formula: C5H7N3. Mole weight: 109.13. | |
Amifampridine Phosphate Quick inquiry Where to buy Suppliers range | Amifampridine is a drug, predominantly used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. Uses: Predominantly in the treatment of a number of rare muscle diseases. Synonyms: phosphoric acid;pyridine-3,4-diamine. Grades: ≥98%. CAS No. 446254-47-3. Molecular formula: C5H10N3O4P. Mole weight: 207.12. | |
AMPK activator Quick inquiry Where to buy Suppliers range | AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. D942 is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, which shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 μM). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Because of the favorable physiological outcomes of AMPK activation on metabolism, AMPK has been considered to be an important therapeutic target for controlling human diseases including metabolic syndrome and cancer. Synonyms: D942; AMPK activator; 5-[3-[4-[2- (4-Fluorophenyl) ethoxy]phenyl]propyl]furan-2-carboxylic Acid. Grades: ≥95%. CAS No. 849727-81-7. Molecular formula: C22H21FO4. Mole weight: 368.4. | |
Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic PA 106, Anhydroscopin A, NSC) Quick inquiry Where to buy Suppliers range | Anisomycin is a phenyl methyl enepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin acts as an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells. Group: Biochemicals. Alternative Names: ((2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate. Grades: Highly Purified. CAS No. 22862-76-6. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
AP-22408 Quick inquiry Where to buy Suppliers range | AP-22408, a Src tyrosine kinase inhibitor, is an orally bioavailable phosphotyrosine mimic resulting from a structurebased design. Synonyms: [4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-phosphonophenyl]phosphonic acid; AP-22408; AP 22408; AP22408; UNII-3U3L5QR4KV; CC1; AC1L9I7C; 3U3L5QR4KV; SCHEMBL7245569. Grades: >98%. CAS No. 268741-43-1. Molecular formula: C30H41N3O10P2. Mole weight: 665.61. | |
Asterriquinone SU5500 Quick inquiry Where to buy Suppliers range | Asterriquinone SU5500 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Synonyms: 2,5-Bis[2-(3-methyl-2-butenyl)-1H-indole-3-yl]-3-acetoxy-6-hydroxy-1,4-benzoquinone. Molecular formula: C34H32N2O5. Mole weight: 548.64. | |
ATPγS Quick inquiry Where to buy Suppliers range | ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in the synthesis of DNA N-acetylglucosamine analogs and a substrate for the RNA-stimulated nucleotide hydrolysis as well as RNA unwinding activities of eukaryotic initiation factor-4A. Uses: Atpγs is an agonist of g protein-coupled p2y2 and p2y11 receptors (pec50 = 5.52 for p2y11). Synonyms: Adenosine-5'-(γ-thio)-triphosphate, Tetralithium salt; Adenosine-5'-(3-thio)-triphosphate, Adenosine-5'-(3-thiotriphosphate). Grades: ≥ 90% by HPLC, contains < 10% ADP. Molecular formula: C10H16N5O12P3S (free acid). Mole weight: 523.24 (free acid). | |
Aurora A inhibitor II Quick inquiry Where to buy Suppliers range | Aurora A inhibitor II is a potent and selective inhibitor of Aurora A kinase (AurA; IC50 = 4.3 nM). Synonyms: 4-[[2-[[4-[2-(4-acetyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-N-(2-chlorophenyl)-Benzamide. Grades: 99%. CAS No. 1158838-43-7. Molecular formula: C31H29ClFN7O3. Mole weight: 602.06. | |
Autocamtide-2-related inhibitory peptide, myristoylated acetate Quick inquiry Where to buy Suppliers range | Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor that blocks the reinstatement of morphine-seeking behavior in vivo by pretreatment. It is an enhanced cell-permeable derivative of autocamtide-2-related inhibitory peptide. Synonyms: AIP Myristoylated acetate; Myr-AIP acetate; N2-(1-Oxotetradecyl)-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-alanyl-L-leucine acetate; m-AIP acetate; Myristoylated autocamtide-2-related inhibitory peptide acetate; H-Lys(myristoyl)-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C80H146N22O22. Mole weight: 1768.15. | |
AZD0424 Quick inquiry Where to buy Suppliers range | AZD0424 is an orally bioavailable small molecule tyrosine kinase inhibitor. It targets both Abl and Src kinases with potential antineoplastic activity. It selectively inhibits both Src and Abl kinase activity and may result in the inhibition of tumor growth in susceptible tumor cells. Uses: Azd0424 has the inhibition of tumor growth in tumor cells. Synonyms: AZD 0424; AZD-0424; 1-(4-(2-((4-((6-chloro-[1,3]dioxolo[4,5-b]pyridin-7-yl)amino)-5-isopropoxyquinazolin-7-yl)oxy)ethyl)piperazin-1-yl)ethan-1-one; 7-(2-(4-Acetylpiperazin-1-yl)ethoxy)-4-(5-chloro-2,3-methylenedioxypyridin-4-ylamino)-5-isopropoxyquinazoline. Grades: 98%. CAS No. 692054-06-1. Molecular formula: C25H29ClN6O5. Mole weight: 528.99. | |
AZD1152, TFA Salt Quick inquiry Where to buy Suppliers range | An Aurora kinase inhibitor, used to treat patients with advanced solid tumors. Group: Biochemicals. Alternative Names: 3-[[7-[3-[Ethyl[2- (phosphonooxy) ethyl]amino]propoxy]-4-quinazolinyl]amino]-N- (3-fluorophenyl) -1H-pyrazole-5-acetamide Trifluoroacetic Acid Salt; Barasertib Trifluoroacetic Acid Salt; AZD-1152 Trifluoroacetic Acid Salt. Grades: Highly Purified. CAS No. 957881-03-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??FN?O?P; x(C ?HF?O?), Molecular Weight: 587.54. US Biological Life Sciences. | Worldwide |
AZD4573 Quick inquiry Where to buy Suppliers range | AZD-4573 (AZD4573) is a potent and selective inhibitor of CDK9, with fast-off binding kinetics and high selectivity versus other kinases. AZD4573 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II, leading to the inhibition of gene transcription of various anti-apoptotic proteins. Synonyms: AZD-4573; AZD 4573; (1S,3R)-3-acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexane-1-carboxamide. Grades: ≥98%. CAS No. 2057509-72-3. Molecular formula: C22H28ClN5O2. Mole weight: 429.94. | |
Berberine chloride hydrate Quick inquiry Where to buy Suppliers range | The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC). Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin. Synonyms: Natural Yellow 18. Grades: >98%. CAS No. 141433-60-5. Molecular formula: C20H18ClNO4. Mole weight: 371.81. | |
β-Galactosyl-C18-ceramide Tetraacetate Quick inquiry Where to buy Suppliers range | β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the β-Galactosyl-C18-ceramide synthesis, which is a galactosylceramides involved in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have important immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-3-hydroxy-2-stearamidooctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C50H89NO12. Mole weight: 896.24. | |
BIO-11006 Quick inquiry Where to buy Suppliers range | BIO-11006 is a myristoylated alanine-rich C kinase substrate (MARCKS) inhibitor, similar to MANS peptides. Synonyms: BIO-11006 peptide; L-Lysine, N-acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-; N-Acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-L-lysine; BIO 11006; BIO11006; Ac-Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Ala-Lys-OH. Grades: ≥95%. CAS No. 901117-03-1. Molecular formula: C46H75N13O15. Mole weight: 1050.17. | |
BIO-11006 acetate salt Quick inquiry Where to buy Suppliers range | BIO-11006 acetate salt, an analog of the MANS peptide, is a myristoylated alanine-rich C kinase substrate (MARCKS) inhibitor. Uses: Peptide Inhibitors. Product ID: R1238. | |
Bisindolylmaleimide VIII acetate Quick inquiry Where to buy Suppliers range | Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor with IC50 of 158 nM for rat brain that acts at the ATP binding site. Bis VIII has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism. BIM VIII does not inhibit the tyrosine phosphorylation or the activation of phospholipase C γ1. BIM VIII inhibits carbachol-evoked noradrenaline release from human SH-SY5Y neuroblastoma cells with an IC50 of 600 nM. Synonyms: BIM VIII; Ro 31-7549. Grades: ≥98%. CAS No. 138516-31-1. Molecular formula: C24H22N4O2·C2H4O2. Mole weight: 458.5. | |
Bisindolylmaleimide VIII acetate Quick inquiry Where to buy Suppliers range | Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Group: Biochemicals. Alternative Names: Ro 31-7549, BIM VIII. Grades: Highly Purified. CAS No. 138516-31-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H22N4O2. CH3COOH. US Biological Life Sciences. | Worldwide |
Bryostatin 3 Quick inquiry Where to buy Suppliers range | Bryostatin 3 has been found to be a potent protein kinase C activator and could probably be useful in studies of emerging cancers. Synonyms: Bryostatin 3; 143370-84-7; (4S, 5S, 7E, 9R, 11Z, 13S, 15S, 17S, 19R, 21R, 25R, 27R, 27aS)-17-(Acetyloxy)-4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester. Grades: ≥95% by HPLC. CAS No. 143370-84-7. Molecular formula: C46H64O17. Mole weight: 888.99. | |
BSJ-Bump Quick inquiry Where to buy Suppliers range | BSJ-Bump is the negative control for BSJ-03-123. It displays binding and no degradation of cyclin dependent kinases 6 (CDK6) in vitro. Synonyms: N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide. Grades: ≥98%. CAS No. 2409918-48-3. Molecular formula: C48H58N10O11. Mole weight: 951.05. | |
C2 Ceramide (N-Acetyl-D-sphingosine, Acetyl Ceramide) Quick inquiry Where to buy Suppliers range | A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; N-Acetyl-D-sphingosine; Acetyl Ceramide; N-Acetylsphingosine. Grades: Highly Purified. CAS No. 3102-57-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 341.53. US Biological Life Sciences. | Worldwide |