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1-(3-Azetidinyl)pyrrolidine Dihydrochloride 1-(3-Azetidinyl)pyrrolidine Dihydrochloride is used as a reactant in the preparation of annelated pyrimidine derivatives useful in the treatment and prophylaxis of cardiovascular diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1024589-68-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H14N2 2HCl, Molecular Weight: 126.2023646. US Biological Life Sciences. USBiological 9
Worldwide
1-Benzhydryl-3-methane sulfonatoazetidine (1-Diphenylmethyl-3-azetidinyl Methanethiosulfonate) A useful intermediate in the synthesis of polypeptides. Group: Biochemicals. Alternative Names: 1-Diphenylmethyl-3-azetidinyl Methanethiosulfonate. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. USBiological 1
Worldwide
(1R)-1-[(2S,3S)-N-Methyl-3-hydroxy-1-azetidinyl]-1,2-ethanediol (1R)-1-[(2S,3S)-N-Methyl-3-hydroxy-1-azetidinyl]-1,2-ethanediol, a revolutionary biomedical substance, exhibits remarkable potential in the management of certain ailments. Its intricate chemical architecture renders it capable of evoking therapeutic effects in diverse pathological states. This exceptional formulation has garnered extensive scientific scrutiny, aiming to elucidate its precise role in targeting distinct receptors or pathways implicated in disease progression. Consequently, it presents a plethora of promising treatment avenues for affected individuals. Rigorous exploration has been undertaken to fully comprehend the extensive scope of (1R)-1-[(2S,3S)-N-Methyl-3-hydroxy-1-azetidinyl]-1,2-ethanediol's therapeutic capabilities within these specific maladies. Molecular formula: C6H14NO3. Mole weight: 148.18. BOC Sciences 12
2-Cyanoacetic acid 1-(diphenylmethyl)-3-azetidinyl ester Heterocyclic Organic Compound. CAS No. 116574-14-2. Molecular formula: C19H18N2O2. Mole weight: 306.36. Purity: 0.98. Catalog: ACM116574142. Alfa Chemistry. 2
[(2S,3S)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamic Acid 1,1-Dimethylethyl Ester Aztreonam intermediate. Group: Biochemicals. Alternative Names: [(2S-trans)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 83542-13-6. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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(2S, ?3S, ?4R) ?-3-?[[[ (2S, ?3S, ?4R) ?-?3-?[[[ (2S, ?3S, ?4R) ?-?3-?Azido-?4-?[[[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?oxy]?methyl]?-?1-? (phenylmethyl) ?-?2-?azetidinyl]?carbonyl]?amino]?-?4-?[[[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?oxy]?methyl]?-?1-? (phenylmethyl) ?-?2-?azetidinyl]?carbonyl]?amino]?-?4-?[[[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?oxy]?methyl]?-?1-? (phenylmethyl) ?-2-?azetidinecarboxylic acid methyl ester (2S, 3S, 4R) -3-[[[ (2S, 3S, 4R) -3-Azido-4-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl]-1- (phenylmethyl) -2-azetidinyl]carbonyl]-4-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl]-1- (phenylmethyl) -2-azetidinyl]carbonyl]-4-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl-1- (phenylmethyl) -2-azetidinecarboxylic acid methyl ester, a novel and highly potent inhibitor, exhibits remarkable selectivity for cancer treatment research. By specifically targeting crucial enzymes implicated in tumor growth and proliferation, this compound induces apoptotic cell death while suppressing angiogenesis. CAS No. 1992035-05-8. Molecular formula: C55H86N8O7Si3. Mole weight: 1055.58. BOC Sciences 12
(2S, ?3S, ?4R) ?-3-?[[[ (2S, ?3S, ?4R) ?-?3-?Azido-?4-?[[[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?oxy]?methyl]?-?1-? (phenylmethyl) ?-?2-?azetidinyl]?carbonyl]?amino]?-?4-?[[[ (1, ?1-?dimethylethyl) ?dimethylsilyl]?oxy]?methyl]?-?1-? (phenylmethyl) ?-2-?azetidinecarboxylic acid methyl ester (2S, 3S, 4R) -3-[[[ (2S, 3S, 4R) -3-Azido-4-[[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl]-1- (phenylmethyl) -2-azetidinyl]carbonyl]amino]-4-[[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl]-1- (phenylmethyl) -2-azetidinecarboxylic acid methyl ester exemplifies a cutting-edge biopharmaceutical of immense therapeutic potential. By selectively targeting and inhibiting critical enzymes or receptors instrumental in the progression of diverse diseases such as cancer, bacterial infections, and viral infections, it efficaciously suppresses their activity, thereby mitigating associated symptoms. CAS No. 1992035-15-0. Molecular formula: C37H58N6O5Si2. Mole weight: 723.06. BOC Sciences 12
3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester Heterocyclic Organic Compound. CAS No. 116574-09-5. Molecular formula: C19H21N3O2. Mole weight: 323.39. Catalog: ACM116574095. Alfa Chemistry. 2
3-Azetidinyl acetate hydrochloride Heterocyclic Organic Compound. Alternative Names: azetidin-3-yl acetate hydrochloride, 3-AZETIDINYL ACETATE HYDROCHLORIDE, 118972-95-5, SureCN2794246, CTK4B0982, MolPort-016-578-640, AKOS015847071, AG-L-20655, FT-0681956, I14-27814, F2147-1188. CAS No. 118972-95-5. Molecular formula: C5H10ClNO2. Mole weight: 151.59. Purity: 0.96. IUPACName: azetidin-3-yl acetate;hydrochloride. Canonical SMILES: CC(=O)OC1CNC1.Cl. Catalog: ACM118972955. Alfa Chemistry. 2
(5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone (5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1341527-09-0. Pack Sizes: 250mg. Molecular Formula: C8H8ClNO2S, Molecular Weight: 217.67. US Biological Life Sciences. USBiological 3
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5-Iodo-A-85380 Dihydrochloride Hydrate (3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine Dihydrochloride Hydrate, a4b2 and a6b2 Nicotinic Acetylcholine Receptors (nAChR) Agonist, 5-Iodo-A-85380) A very potent agonist highly selective for alpha4beta2 and alpha6beta2 nicotinic acetylcholine receptors (nAChR) (Ki= 12 and 10 pM for human and rat alpha4beta2 nAChRs, respectively). An important nAChR ligand for the treatment of pain, smoking addition and other mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 213550-82-4. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 4
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(E)-2-[n-[(2S)-2,3-Dihydroxy-1-oxopropyl]-d-serylamino]-N-[(3R)-2-oxo-1-sulfo-3-azetidinyl]-2-butenediamide Heterocyclic Organic Compound. CAS No. 108065-95-8. Catalog: ACM108065958. Alfa Chemistry. 4
[Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone [Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1392443-41-2. Pack Sizes: 10mg. Molecular Formula: C25H25N5O3S, Molecular Weight: 463.55. US Biological Life Sciences. USBiological 3
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L-Arginine,mixt. with2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoicacid Heterocyclic Organic Compound. CAS No. 104184-69-2. Molecular formula: C13H17N5O8S2. Catalog: ACM104184692. Alfa Chemistry. 5
N-?[[ (2R, ?3R, ?4S) ?-?4-?[ (Acetyloxy) ?methyl]?-?3-? (phenylmethoxy) ?-?1-? (phenylmethyl) ?-?2-?azetidinyl]?methyl]?-acetamide N-[[ (2R, ?3R, ?4S)?-4-[ (Acetyloxy)?methyl]?-3- (phenylmethoxy)?-1- (phenylmethyl)?-2-azetidinyl]?methyl]?-acetamide, a medicinal compound of virtue, is an indispensable medication for patients affected by hypertension and congestive heart failure. Acting as an enzyme inhibitor for the notorious angiotensin converting enzyme (ACE), this agent precludes the production of angiotensin II, responsible for narrowing blood vessels and consequently leading to fluctuations in blood pressure and flow. Let the compound enter the realm of human life and restore their vigor and vitality. CAS No. 1591783-54-8. Molecular formula: C23H28N2O4. Mole weight: 396.48. BOC Sciences 11
N-[(2S,3S)-2-Methyl-4-oxo-3-azetidinyl]-carbamic Acid 1,1-Dimethylethyl Ester Aztreonam intermediate. Group: Biochemicals. Alternative Names: (2S-trans)-2-Methyl-4-oxo-3-azetidinyl]-carbamic Acid 1,1-Dimethylethyl Ester; N-[(2S,3S)-2-Methyl-4-oxo-3-azetidinyl]-carbamic Acid tert-Butyl Ester. Grades: Highly Purified. CAS No. 80582-03-2. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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N- [3- [ [2- [ [4- [ [1- (2-Fluoroethyl) -3-azetidinyl] amino] -2-methoxyphenyl] amino] -5- (trifluoromethyl) -4-pyrimidinyl] amino] phenyl] -2-propenamide N- [3- [ [2- [ [4- [ [1- (2-Fluoroethyl) -3-azetidinyl] amino] -2-methoxyphenyl] amino] -5- (trifluoromethyl) -4-pyrimidinyl] amino] phenyl] -2-propenamide. Group: Biochemicals. Alternative Names: CNX-2006. Grades: Highly Purified. CAS No. 1375465-09-0. Pack Sizes: 5mg. Molecular Formula: C26H27F4N7O2, Molecular Weight: 545.53. US Biological Life Sciences. USBiological 3
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(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester Intermediate for synthesis of D,L-Alanosine. Group: Biochemicals. Alternative Names: [(3R,S)-2-Oxo-1-(phenylmethoxy)-3-azetidinyl]carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 1246814-58-3. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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(S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester (S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester. Group: Biochemicals. Alternative Names: [(3S)-2-Oxo-1-(phenylmethoxy)-3-azetidinyl]carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 71404-99-4. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
Worldwide
tert-Butyl 1-benzhydryl-3-azetidinylcarbamate tert-Butyl 1-benzhydryl-3-azetidinylcarbamate. Group: Biochemicals. Grades: Reagent Grade. CAS No. 91189-18-3. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. USBiological 5
Worldwide
1-(2,4-Difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid 1-(2,4-Difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is an intermediate used to prepare hydrazinoquinolones and azetidinylquinolinones derivatives as antibacterial agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 103995-01-3. Pack Sizes: 5mg, 50mg. Molecular Formula: C16H7F4NO3, Molecular Weight: 337.23. US Biological Life Sciences. USBiological 9
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1-Benzhydryl-3-methane sulfonatoazetidine 1-Benzhydryl-3-methane sulfonatoazetidine. Group: Biochemicals. Alternative Names: 1-Diphenylmethyl-3-azetidinyl methanethiosulfonate; 1-(Diphenylmethyl)-3-(mesyloxy)azetidine; 1- (Diphenylmethyl) -3-[ (methylsulfonyl) oxy]azetidine. Grades: Highly Purified. CAS No. 33301-41-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C17H19NO3S. US Biological Life Sciences. USBiological 6
Worldwide
1-Benzyl-3-aminomethyl-azetidine dihydrochloride Heterocyclic Organic Compound. Alternative Names: (1-Benzylazetidin-3-yl)methanamine, 1219967-55-1, CTK7E6798, MolPort-016-578-535, (1-Benzyl-3-azetidinyl)methanamine, AKOS005264630, AG-L-57212, AK-43369, BB 0261965, X9512. CAS No. 1219967-55-1. Molecular formula: C11H18Cl2N2. Mole weight: 176.258140 [g/mol]. Purity: 0.96. IUPACName: (1-benzylazetidin-3-yl)methanamine. Catalog: ACM1219967551. Alfa Chemistry. 5
1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid Methyl Ester 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid Methyl Ester is the methyl ester derivative of 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid (P998590) and is used as a reagent in the synthesis of azetidinylpiperidine derivatives as monoacylglycerol lipase inhibitors useful in the treatment of inflammatory pain. Group: Biochemicals. Grades: Highly Purified. CAS No. 1015609-11-6. Pack Sizes: 50mg, 500mg. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences. USBiological 9
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(2R) -1-Boc-2- (hydroxymethyl) azetidine (2R) -1-Boc-2- (hydroxymethyl) azetidine was used to study analgesic structure activity relationship of (azetidinylmethoxy) chloropyridine derivatives. It is used for efficient asymmetric synthesis of oral analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 161511-90-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H17NO3, Molecular Weight: 187.24. US Biological Life Sciences. USBiological 10
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3-(N-Boc-ethylamino) azetidine 3-(N-Boc-ethylamino) azetidine. Group: Biochemicals. Alternative Names: tert-Butyl N-(azetidin-3-yl)-N-(ethyl)carbamate; N-3-Azetidinyl-N-ethylcarbamic acid 1,1-dimethylethyl ester. Grades: Highly Purified. CAS No. 929716-69-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H20N2O2. US Biological Life Sciences. USBiological 6
Worldwide
3-O-Acetyl Ezetimibe 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. CAS No. 190448-56-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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3-O-Acetyl Ezetimibe-d4 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester Labeled intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl-d4)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
3-Phthalimidoazetidine 3-Phthalimidoazetidine. Group: Biochemicals. Alternative Names: 2-(3-Azetidinyl)-1H-isoindol-1,3(2H)-dione. Grades: Highly Purified. CAS No. 104390-83-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C11H10N2O2. US Biological Life Sciences. USBiological 8
Worldwide
3-Phthalimidoazetidine Heterocyclic Organic Compound. Alternative Names: 3-PHTHALIMIDOAZETIDINE;2-(3-Azetidinyl)-1H-isoindol-1,3(2H)-dione. CAS No. 104390-83-2. Molecular formula: C11H10N2O2. Mole weight: 202.2093. Catalog: ACM104390832. Alfa Chemistry. 5
5-Iodo-A-85380 dihydrochloride 5-Iodo-A-85380 dihydrochloride is the dihydrochloride salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. It activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes. Synonyms: Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2); (S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride; 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217837-17-6. Molecular formula: C9H13IN2OCl2. Mole weight: 363.03. BOC Sciences 10
A 85380 dihydrochloride A 85380 dihydrochloride is a selective α4β2 nACh receptor agonist (Ki = 0.05, 148 and 314 nM for α4β2, α7 and α1β1δγ receptors, respectively). Synonyms: A 85380 dihydrochloride; A85380 dihydrochloride; A-85380 dihydrochloride; 3-[(2S)-2-Azetidinylmethoxy]-pyridine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 174740-86-4. Molecular formula: C9H12N2O.2HCl. Mole weight: 237.13. BOC Sciences 2
ARD-2585 ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer. Synonyms: Benzamide, N-[trans-4-[(3-chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]-; N- ( (1r, 4r)-4- ( (3-chloro-4-cyanophenyl) (methyl)amino)cyclohexyl)-4- (4- (1- (2- (2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-5-yl)azetidin-3-yl)piperazin-1-yl)benzamide; N-[trans-4-[(3-Chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]benzamide; ARD 2585; ARD2585. CAS No. 2757422-79-8. Molecular formula: C41H43ClN8O5. Mole weight: 763.28. BOC Sciences 2
Azelnidipine Azelnidipine is a dihydropyridine calcium channel blocker with antihypertensice activity. Azelnidipine is used for treating ischemic heart disease and cardiac remodeling after myocardial infarction. Studies show that Azelnidipine ttreatment can reduce the risk of hyperglycemia induced metabolic disorders. Group: Biochemicals. Alternative Names: (±)-2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) Ester; Azelnidipine; CS 905; Calblock 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-isopropyl (±)-2-Amino-1,4-dihydro-6-methyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate. Grades: Highly Purified. CAS No. 123524-52-7. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
Worldwide
Aztreonam Aztreonam inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a very high affinity for penicillin-binding protein-3 and mild affinity for penicillin-binding protein-1a. Aztreonam binds the penicillin-binding proteins of Gram-positive and anaerobic bacteria very poorly and is largely ineffective against them. Synonyms: Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-; Az threonam; Az-threonam; Azactam; Azthreonam; Urobactam; 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid; Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2S-[2α,3β(Z)]]-; Antibiotic Squibb 26,776; Azonam; Aztreon; Nebactam; Primbactam; SQ 26776; Squibb 26776. Grades: >98%. CAS No. 78110-38-0. Molecular formula: C13H17N5O8S2. Mole weight: 435.43. BOC Sciences
Aztreonam The first totally synthetic monocyclic β-lactam antibiotic. Group: Biochemicals. Alternative Names: [2S-[2α,3 β (Z) ] ] -2- [ [ (Z) - [1- (2-Amino-4-thiazolyl) -2- [ [ (2S, 3S) -2-methyl-4-oxo-1-sulfo-3-azetidinyl] amino] -2-oxoethylidene] amino] oxy] -2-methylpropanoic Acid; Azthreonam; Aztreon; Monobactam; Nebactam;SQ 26776; Squibb 26776. Grades: Highly Purified. CAS No. 78110-38-0. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 2
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Aztreonam impurity E Aztreonam impurity E is the (E)-isomer of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Uses: Anti-bacterial agents. Synonyms: (E)-Aztreonam; Aztreonam USP RC E; Aztreonam USP Impurity E; Aztreonam E-Isomer; (E) -2- ({ [ (2-Amino-4-thiazolyl) { [ (2S, 3S) -2-methyl-4-oxo-1-sulfo-3-azetidinyl] carbamoyl}methylene] amino}oxy) -2-methylpropionic acid. Grades: 98%. CAS No. 99341-02-3. Molecular formula: C13H17N5O8S2. Mole weight: 435.43. BOC Sciences
BMS 180680 BMS 180680 is antibacterial activity agent of new catechol-containing monobactam. It is a cell wall inhibitor. BMS-180680 is an active compound against many species of the family Enterobacteriaceae, with MICs at which 90% of the isolates were inhibited. In Oct 2002, Phase-II for Respiratory tract infections in USA was discontinued. Uses: Respiratory tract infections. Synonyms: BMS 180680; BMS180680; BMS-180680; SQ 84,100;(2R-(2alpha,3alpha(Z)))-3-((((1-(2-Amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)methyl)-6,7-dihydroxy-2-quinoxalinecarboxylic acid. Grades: 98%. CAS No. 142654-34-0. Molecular formula: C19H17N7O10S2. Mole weight: 567.51. BOC Sciences 10
Buttpark 92\50-60 Heterocyclic Organic Compound. Alternative Names: BUTTPARK 92\50-60;N-[1-(DIPHENYLMETHYL)-3-AZETIDINYL]-ACETAMIDE. CAS No. 102065-87-2. Molecular formula: C18H20N2O. Mole weight: 280.36. Catalog: ACM102065872. Alfa Chemistry. 3
Camizestrant Camizestrant is an orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Synonyms: N-[1-(3-fluoropropyl)azetidin-3-yl]-6-[(6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl]pyridin-3-amine; Estrogen receptor antagonist 2; AZD-9833; AZD 9833; AZD9833; NSC-828717; N-[1-(3-Fluoropropyl)-3-azetidinyl]-6-[(6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl]-3-pyridinamine. Grades: ≥98%. CAS No. 2222844-89-3. Molecular formula: C24H28F4N6. Mole weight: 476.51. BOC Sciences 10
Cilofexor Cilofexor is a farnesoid X receptor (FXR) agonist. Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). Synonyms: 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 1418274-28-8. Molecular formula: C28H22Cl3N3O5. Mole weight: 586.9. BOC Sciences 8
Cobimetinib hemifumarate Cobimetinib, also known as GDC-0973 and XL-518, is a novel selective MEK inhibitor, and the IC50value against MEK1 is 4.2 nM, with potential antineoplastic activity. Synonyms: Methanone, [3,?4-difluoro-2-[(2-fluoro-4-iodophenyl)?amino]?phenyl]?[3-hydroxy-3-(2S)?-2-piperidinyl-1-azetidinyl]?-, (2E)?-2-butenedioate (2:1). CAS No. 1369665-02-0. Molecular formula: C21H21F3IN3O2.1/2C4H4O4. Mole weight: 589.35. BOC Sciences 10
Dehydro Azelnidipine Dehydro Azelnidipine is a derivative of Azelnidipine. Synonyms: 2-Amino-6-methyl-4-(3-nitrophenyl)-3-[1-(diphenylmethyl)-3-azetidinyl]-3,5-pyridinedicarboxylic Acid 5-(1-Methylethyl) Ester. Grades: > 95%. CAS No. 918659-10-6. Molecular formula: C33H32N4O6. Mole weight: 580.65. BOC Sciences 7
Desulfo aztreonam Heterocyclic Organic Compound. Alternative Names: [2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic Acid. CAS No. 102579-59-9. Molecular formula: C13H17N5O5S. Mole weight: 355.37. Purity: 0.96. IUPACName: 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid. Catalog: ACM102579599. Alfa Chemistry. 3
Desulfo Aztreonam tert-Butyl Ester Aztreonam. Group: Biochemicals. Alternative Names: [2S-[2α,3 β (Z) ] ] -2- [ [ [1- (2-Amino-4-thiazolyl) -2- [ (2-methyl-4-oxo-3-azetidinyl) amino] -2-oxoethylidene] amino] oxy] -2-methylpropanoic Acid tert-Butyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
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(E)-Aztreonam (E)-Aztreonam. Group: Biochemicals. Alternative Names: 2- [ [ (E) - [1- (2-Amino-4-thiazolyl) -2- [ [ (2S, 3S) -2-methyl-4-oxo-1-sulfo-3-azetidinyl] amino] -2-oxoethylidene] amino] oxy] -2-methyl-propanoic Acid; SQ 28429. Grades: Highly Purified. CAS No. 99341-02-3. Pack Sizes: 1mg. Molecular Formula: C13H17N5O8S2, Molecular Weight: 435.43. US Biological Life Sciences. USBiological 3
Worldwide
Ezetimibe-d4 β-D-Glucuronide Phase-II labeled metabolite of Ezetimibe, an antihyperlipoproteinem ic. A cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid; Ezetimibe-d4 Phenoxy Glucuronide; Sch 58235-d4 Glucuronide; Sch 60663-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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Ezetimibe Hydroxy Glucuronide A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Hydroxy β-D-Glucuronide; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 536709-33-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. BOC Sciences 11
Faropenem Related Compound 1 An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (2R)?- 2-Furancarbothioic acid, tetrahydro-, S-[ (2R, ?3S) ?-3-[ (1R) ?-1-[[ (1, ?1-dimethylethyl) ?dimethylsilyl]?oxy]?ethyl]?-4-oxo-2-azetidinyl] ester. Grades: > 95%. CAS No. 106560-32-1. Molecular formula: C16H29NO4SSi. Mole weight: 359.56. BOC Sciences 8
GLPG 0974 GLPG 0974 is a potent FFA2 antagonist (IC50 = 9 nM) with selectivity for FFA2 over FFA3. It was shown that GLPG 0974 inhibited acetate-induced human neutrophil migration in plasma or buffer, and also suppressed FFA2-induced expression of CD11b activation-specific epitope (AE) in human whole blood. Synonyms: GLPG0974; GLPG 0974; GLPG-0974. 4-[[[(2R)-1-(Benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]butanoic acid. Grades: ≥98% by HPLC. CAS No. 1391076-61-1. Molecular formula: C25H25ClN2O4S. Mole weight: 485. BOC Sciences 9
Isosulfazecin Isosulfazecin is a beta-lactam antibiotic produced by the strain of Pseudomonas mesoacidophila sp. nov. Its anti-gram-positive bacteria effect is similar to SZ (Sulfazecin), but its anti-gram-negative bacteria activity is weaker than SZ. Synonyms: (R)-D-gamma-Glutamyl-N-(3-methoxy-2-oxo-1-sulfo-3-azetidinyl)-L-alaninamide; (3R) -2-Oxo-3-methoxy-3beta- [ [N- [ (4R) -4-amino-4-carboxybutyryl] alanyl] amino] azetidine-1-sulfonic acid. Grades: >98%. CAS No. 77900-75-5. Molecular formula: C12H20N4O9S. Mole weight: 396.38. BOC Sciences 5
JNJ-41443532 This active molecular is a CCR2 receptor antagonist which is applicated for the treatment of type-2 diabetes mellitus under the development of Janssen Research & Development. In 2010, Phase-I clinical trials in Type-2 diabetes mellitus was on-going. in Belgium and USA. Uses: Type-2 diabetes mellitus. Synonyms: JNJ-41443532; JNJ 41443532; JNJ41443532; JNJ-41443532 Free Base; N-(2-((1-(trans-4-hydroxy-4-(5-thiazolyl)cyclohexyl)-3-azetidinyl)amino)-2-oxoethyl)-3-(trifluoromethyl)Benzamide. Grades: 98%. CAS No. 1228650-83-6. Molecular formula: C22H25F3N4O3S. Mole weight: 482.52. BOC Sciences 10
Melagatran Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic. Group: Biochemicals. Alternative Names: N- [ (1R) -2- [ (2S) -2- [ [ [ [4- (Aminoiminomethyl) phenyl] methyl] amino] carbonyl] -1-azetidinyl] -1-cyclohexyl-2-oxoethyl] glycine; H-319/68. Grades: Highly Purified. CAS No. 159776-70-2. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Nav1.7-IN-2 Nav1.7-IN-2, a voltage-gated sodium channels, could be probably effective in chronic pain therapy. IC50: 80 nM. Uses: Nav1.7-in-2 is a voltage-gated sodium channels and could be probably effective in chronic pain therapy. Synonyms: Benzamide, 3-[[4-[3-(4-fluoro-2-methylphenoxy)-1-azetidinyl]-2-pyrimidinyl]amino]-N-methyl-. Grades: 98%. CAS No. 1332295-35-8. Molecular formula: C22H22FN5O2. Mole weight: 407.44. BOC Sciences 10
N-Boc-2-trimethylammonium-A 85380 triflate N-Boc-2-trimethylammonium-A 85380 triflate. Group: Biochemicals. Alternative Names: 3-[[ (2S) -1-[ (1, 1-Dimethylethoxy) carbonyl]-2-azetidinyl]methoxy]-N, N, N-trimethyl-2-pyridinaminium. Grades: Highly Purified. CAS No. 233766-75-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C18H28F3N3O6S. US Biological Life Sciences. USBiological 6
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N-Hydroxy Melagatran An N-Hydroxyguanidine prodrug and intermediate in the preparation of Melagatran. Group: Biochemicals. Alternative Names: N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine; Melagatran Hydroxyamidine. Grades: Highly Purified. CAS No. 192939-72-3. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 445.51. US Biological Life Sciences. USBiological 2
Worldwide
PF 04449613 PF 04449613 is a potent PDE9 inhibitor (IC50 = 22 nM), and also shows a high affinity for cGMP (Km ~170 nM). Some studies suggest that elevating the level of cGMP with the PDE9 inhibitor PF-04449613 increases synaptic calcium activity and learning-dependent synaptic plasticity. Synonyms: (R)-6-(1-(3-Phenoxyazetidin-1-yl)ethyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one; 1,5-Dihydro-6-[(1R)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-[(1R)-1-(3-Phenoxyazetidin-1-yl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; PF 4449613; PF 9613; PF4449613; PF9613; PF-4449613; PF-9613. Grades: ≥98% by HPLC. CAS No. 1236858-52-8. Molecular formula: C21H25N5O3. Mole weight: 395.45. BOC Sciences 10
PF 05180999 PF 05180999 is a potent and selective PDE2A inhibitor (IC50 = 1 nM), with 2000-fold selectivity for PDE2A over PDE10A. PF 05180999 was evaluated for schizophrenia and migraine, but no further development has been reported since 2014. Synonyms: 4-(1-Azetidinyl)-7-methyl-5-[1-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-4-yl]-imidazo[5,1-f][1,2,4]triazine; PF05180999; PF-05180999; PF 5180999; PF5180999; PF-5180999; PF 5180999; PF999; PF-999; PF 999. Grades: ≥98% by HPLC. CAS No. 1394033-54-5. Molecular formula: C19H17F3N8. Mole weight: 414.39. BOC Sciences 10
PF-05231023 PF-05231023 is a long-acting FGF21 mimic. PF-05231023 can reduce the weight of non-human primates and patients with type 2 diabetes and improve blood lipid status. It is a PEG-based PROTAC linker that can be used to synthesize PROTAC. Synonyms: Mal-Amido-PEG2-C2-Amido-Ph-C2-CO-AZD; 2, 5-Dihydro-2, 5-Dioxo-N- (2- (2- (3-Oxo-3- ( (4- (3-Oxo-3- (2-Oxo-1-Azetidinyl) Propyl) Phenyl) Amino) Propoxy) Ethoxy) Ethyl) -1H-Pyrrole-1-Propanamide; 2, 5-Dihydro-2, 5-Dioxo-N- [2- [2- [3-Oxo-3- [ [4- [3-Oxo-3- (2-Oxo-1-Azetidinyl) Propyl] Phenyl] Amino] Propoxy] Ethoxy] Ethyl] -1H-Pyrrole-1-Propanamide. Grades: ≥98% by HPLC. CAS No. 1037589-69-7. Molecular formula: C26H32N4O8. Mole weight: 528.6. BOC Sciences 9
PF 945863 PF 945863, an orally active macrolide antibiotic, is active against multidrug resistant respiratory tract bacterial strains. Synonyms: PF 945863; PF945863; PF-945863; (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[1-[(1R)-1-(1,8-naphthyridin-4-yl)ethyl]-3-azetidinyl]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)tetrone. Grades: ≥98% by HPLC. CAS No. 893556-85-9. Molecular formula: C44H65N5O10. Mole weight: 824.01. BOC Sciences 10
(R)-XL518 (R)-XL518. Group: Biochemicals. Alternative Names: [3, 4-Difluoro-2-[ (2-fluoro-4-iodophenyl) amino]phenyl][3-hydroxy-3-[ (2R) -2-piperidinyl]-1-azetidinyl]methanone; (R)-XL 518. Grades: Highly Purified. CAS No. 934660-94-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H21F3IN3O2. US Biological Life Sciences. USBiological 8
Worldwide
(S)-3-(N-Boc-amino)-1-hydroxy-2-azetidinone (S)-3-(N-Boc-amino)-1-hydroxy-2-azetidinone. Group: Biochemicals. Alternative Names: 3-[(tert-Butoxycarbonyl)amino]-1-hydroxy-2-azetidinone;(S)-(1-Hydroxy-2-oxo-3-azetidinyl)carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 71405-01-1. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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Sazetidine A Dihydrochloride Sazetidine A Hydrochloride is an α4 β2 nicotinic receptor desensitizing agent that exhibits analgesic properties. Sazetidine A Hydrochloride may be used to develop treatments and therapies that aid smoking cessation. Group: Biochemicals. Alternative Names: 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol dihydrochloride. Grades: Highly Purified. CAS No. 1197329-42-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 333.25. US Biological Life Sciences. USBiological 5
Worldwide
Sazetidine A hydrochloride Sazetidine A hydrochloride is an α4β2 nicotinic acetylcholine receptor ligand (Ki = 0.26 and 54 nM at α4β2 and α3β4 receptors, respectively), displaying analgesic activity in vivo. Sazetidine A hydrochloride may act as a silent desensitizer or an agonist. Synonyms: 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol hydrochloride. Grades: ≥98% by HPLC. CAS No. 1197329-42-2. Molecular formula: C15H20N2O2.HCl. Mole weight: 296.797. BOC Sciences 10
tert-Butyl 1-benzylazetidin-3-ylcarbamate Heterocyclic Organic Compound. Alternative Names: 1000577-78-5, TERT-BUTYL 1-BENZYLAZETIDIN-3-YLCARBAMATE, tert-Butyl (1-benzylazetidin-3-yl)carbamate, SureCN1815532, MolPort-000-140-359, AKOS005258645, AK-38934, KB-259980, B-1690, A800032, tert-butyl N-[1-(phenylmethyl)azetidin-3-yl]carbamate, N-[1-(phenylmethyl)-3-azetidinyl]carbamic acid tert-butyl ester. CAS No. 1000577-78-5. Molecular formula: C15H22N2O2. Mole weight: 262.35. Purity: 0.96. IUPACName: tert-butyl N-(1-benzylazetidin-3-yl)carbamate. Catalog: ACM1000577785. Alfa Chemistry. 2
tert-butyl 2-(((Z)-(1-(2-aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4-oxoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methyl propanoate It's one of Aztreonam impurities, Aztreonam is a monobactam antibiotic used primarily to treat gram-negative bacterial infections. Synonyms: tert-Butyl 2-((((Z)-1-(2-aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4-oxoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoate; 2-Methyl-2-propanyl 2-({(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-3-azetidinyl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoate; Propanoic acid, 2-[[[(1Z)-1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-, 1,1-dimethylethyl ester. Grades: 98%. Molecular formula: C17H25N5O5S. Mole weight: 411.48. BOC Sciences 7
Ximelagatran An orally active direct thrombin inhibitor; prodrug of Melagatran. Antithrombotic. Group: Biochemicals. Alternative Names: N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine Ethyl Ester; Exanta; H 376/95. Grades: Highly Purified. CAS No. 192939-46-1. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
Ximelagatran Ximelagatran, an ester prodrug of melagatran, with anticoagulant effect, is the first member of direct thrombin inhibitors that can be taken orally. Uses: An orally active direct thrombin inhibitor; prodrug of melagatran. antithrombotic. Synonyms: H 376-95; H 376/95; H 37695; H-37695; H37695; N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine Ethyl Ester; Exanta; H 376/95. Grades: >98%. CAS No. 192939-46-1. Molecular formula: C24H35N5O5. Mole weight: 473.57. BOC Sciences 8
Ximelagatran Nitrile Intermediate in the preparation of Ximelagatran. Group: Biochemicals. Alternative Names: N-[ (1R) -2-[ (2S) -2-[[[ (4-Cyanophenyl) methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]glycine Ethyl Ester. Grades: Highly Purified. CAS No. 260790-61-2. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
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