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Ligand for palladium-catalyzed synthesis of oxindoles by amide ?-arylation. Ligand for palladium-catalyzed alkoxycarbonylation of aryl chlorides. Ligand for ruthenium-catalyzed alcohol-allene C-C coupling reaction via hydrohydroxyalkylation of 1,1-disubstituted allenes employing alcohols. Ligand for nickel-catalyzed cross-coupling reaction of arylboronic acids with aryl carbonates. Ligand for palladium-catalyzed regiodivergent hydroesterification of aryl olefins with phenyl formate to form linear structured phenyl arylpropanoates. Ligand for palladium-catalyzed direct borylation of benzyl alcohol and its analogues in the absence of bases. Group: Organic phosphine compounds. Alternative Names: 1,1-Bis(dicyclohexylphosphino)ferrocene; 1,1-Bis(Dicyclohexylphosphino)Ferrocene; 1,1-BIS(DICYCLOHEXYLPHOSPHINO)FERROCENE. CAS No. 146960-90-9. Molecular formula: C34H52FeP2. Mole weight: 578.57. Appearance: Orange-red powder. Purity: 0.98. IUPACName: dicyclohexyl(cyclopentyl)phosphane; iron. Canonical SMILES: C1CCC (CC1)P (C2CCCCC2)[C]3[CH][CH][CH][CH]3. C1CCC (CC1)P (C2CCCCC2)[C]3[CH][CH][CH][CH]3. [Fe]. Catalog: ACM146960909.
formate dehydrogenase
The enzyme from most aerobic organisms is devoid of redox-active centres but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centres, flavin and a molybdenum centre. Together with EC 1.12.1.2 hydrogen dehydrogenase, forms a system previously known as formate hydrogenlyase. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1125; formate dehydrogenase; EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: EXWM-1125.
Formate Dehydrogenase (Crude Enzyme)
Formate Dehydrogenases are a set of enzymes that catalyse the oxidation of formate to carbon dioxide, donating the electrons to a second substrate, such as NAD + in formate:NAD + oxidoreductase (EC 1. 2. 1. 2) or to a cytochrome in formate:ferricytochrome-b1 oxidoreductase (EC 1. 2. 2. 1). This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis; biotechnology; medicine; analysis. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Pack: 100ml. Cat No: NATE-1799.
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Fdh is an abundant enzyme from yeast candida boidinii (cbfdh) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants. Applications: Formate dehydrogenase (fdh) is used for diagnostics in large scale industrial pr ocesses. its used in the production of an unnatural amino acid, tert-l-leucine, a component of some hiv protease and matrix metalloprotease inhibitors. Group: Enzymes. Synonyms: EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Activity: Type I, 5.0-15.0 units/mg protein; Type II, 0.3-0.6 units/mg; Type III, ~50 U/mL. Storage: -20°C. Form: Type I, lyophilized powder; Type II, powder; Type III, clear brown liquid. Source: Candida boidinii. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-0254.
Native Yeast Formate Dehydrogenase
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Dehydrogenase that catalyzes the interconversion of formate to carbon dioxide. rely on the proven diagnostic quality of this product. Applications: Use formate dehydrogenase in diagnostic tests for the determination of oxalate in combination with oxalate decarboxylase or for the determination of formic acid. also used in cofactor recycling systems for nadh. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. FDH. Activity: >0.4 U/mg. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: White lyophilizate. Source: Yeast. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formatebenzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-0978.
N-(Benzyloxycarbonyloxy)Succinimide
N-(Benzyloxycarbonyloxy)Succinimide is a reagent used in the preparation of peptide thioacids view peptide precursors. Also used in the preparation of aminoglycoside derivatives for the function of topoisomerase, both human and bacterial inhibition. Synonyms: Benzyl N-succinimidyl carbonate; N-Carbobenzoxyoxysuccinimide; O-Cbz-N-hydroxysuccinimide; Nα-(Benzyloxycarbonyloxy) Succinimide; Z-ONSU; CBZ-O-NHS; benzyl succinimidyl carbonate; 2,5-dioxoazolidinyl (phenylmethoxy)formate; 1-{[ (benzyloxy)carbonyl]oxy}pyrrolidine-2, 5-dione; Z-OSu; N-(N-Benzyloxycarbonyloxy)succinimide. Grades: 98 % (HPLC). CAS No. 13139-17-8. Molecular formula: C12H11NO5. Mole weight: 249.22.
N-CBZ-ALA-ALA-LYS 4-METHOXY-B-NAPHTHYLAM IDE FORMAT
1,3,4-Tri-O-benzyl-2-O-(4-methoxybenzylidene)-b-D-galactopyranoside, a chemical reagent of paramount importance, finds extensive utilization in glycosidic bond synthesis of carbohydrates. It serves as a preferred option for preparing glycosyl donors/acceptors in the formation of oligosaccharides and glycoconjugates. Its popularity among chemical scientists is mainly due to its potential in facilitating synthetic procedures with enhanced complexity and diversity. Molecular formula: C35H36O7. Mole weight: 568.66.
2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl trichloroacetimidate is a biochemical reagent often used in organic synthesis. Primarily, it's used in the biomedical field for the formation of glycosidic bonds and thence production of antiviral drugs. Synonyms: 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl trichloroacetimidate; (2R,3R,4S,5R,6R)-3,4,5-Tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl 2,2,2-trichloroacetimidate; 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl trichloroacetimidate; [(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl] 2,2,2-trichloroethanimidate; C36H36Cl3NO6; SCHEMBL3386829; DTXSID10453689; 2,3,4,6-Tetra-O-benzyl-D-glucopyranosyl trichloroacetimidate; MFCD03427010; AKOS015889374; AS-71301; 2 3 4 6-TETRA-O-BENZYL-alpha-D-GLUCOPYR&; A934059; 2,3,4,6-Tetra-O-benzyl- alpha -D-glucopyranosyl trichloroacetimidate; (2R,3R,4S,5R,6R)-3,4,5-Tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl2,2,2-trichloroacetimidate; (2R,3R,4S,5R,6R)-3,4,5-TRIS(BENZYLOXY)-6-[(BENZYLOXY)METHYL]OXAN-2-YL 2,2,2-TRICHLOROETHANIMIDATE. CAS No. 74808-09-6. Molecular formula: C36H36Cl3NO6. Mole weight: 685.03.
2,3,4-Tri-O-benzyl-a-D-glucuronic acid benzyl ester trichloroacetimidate is a catalyst in the formation of both glycosides and disaccharides. CAS No. 184698-69-9. Molecular formula: C36H34Cl3NO7. Mole weight: 699.02.
2,3-di-O-benzyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin is a modified cyclodextrin used in the formation of complex structures for the delivery of various drugs. Specifically, it assists in improving the solubility and bioavailability of poorly soluble pharmaceuticals. Synonyms: Octakis-(2,3-di-O-benzyl-6-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C208H288O40SI8. Mole weight: 4475.79.
2,4-O-Benzylidene-1-O-tosyl-D-threitol
2,4-O-Benzylidene-1-O-tosyl-D-threitol, a chemical entity, finds application in the realm of neurodegenerative disorders, such as Alzheimer's and Parkinson's. It manifests its potential through inhibition of certain enzymes, catalyzing beta-amyloid plaque formation, which is known to augment disease pathogenesis. This compound, hence, displays prospective therapeutic benefits in the management of aforementioned neurological maladies.
2,6-Di-O-acetyl-3,4-di-O-benzyl-a-D-mannopyranosyl trichloroactimidate is a reagent facilitating the synthesis of intricate carbohydrates and glycoconjugates.This substantive merchandise harbors remarkable utilities in drug development, predominantly enabling the precise adaptation of biologically potent molecules alongside the formation of innovative therapeutic agents, effectively challenging formidable maladies such as cancer and infectious diseases. Molecular formula: C26H28Cl3NO8. Mole weight: 588.86.
2-Benzyl-5-chlorobenzaldehyde
2-Benzyl-5-chlorobenzaldehyde is an intermediate in the formation of 2-Chloroanthracene (C364390), a chlorinated anthracene with mutagenicity that is usually formed following water disinfection with chlorine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1292302-63-6. Pack Sizes: 1g, 5g. Molecular Formula: C14H11ClO. US Biological Life Sciences.
Worldwide
2-Benzyl-5-chlorobenzaldehyde-13C6
2-Benzyl-5-chlorobenzaldehyde-13C6 is an isotope labelled intermediate in the formation of 2-Chloroanthracene (C364390), a chlorinated anthracene with mutagenicity that is usually formed following water disinfection with chlorine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C813C6H11ClO. US Biological Life Sciences.
Worldwide
2-Des(acetylthiomethyl)-2-methylene Racecadotril
2-Des(acetylthiomethyl)-2-methylene Racecadotril. Uses: For analytical and research use. Group: Impurity standards. CAS No. 87428-99-7. Pack Sizes: 2.5G. IUPAC Name: benzyl 2-(2-benzylprop-2-enoylamino)acetate. Molecular Formula: C19H19NO3. Mole Weight: 309.36. Catalog: APS87428997. SMILES: C=C(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2. Format: Neat. Shipping: Room Temperature.
2-(Di-tert-butylphosphino)biphenyl
Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates. Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates. Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides. Effective ligand used in palladium-catalyzed arylation of thiazoles. Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation. Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones. Group: Organic phosphine compounds. Alternative Names: (2-Biphenylyl)-Di-Tert-Butylphosphine. CAS No. 224311-51-7. Molecular formula: C20H27P. Mole weight: 298.4. Appearance: Solid. Purity: 0.98. IUPACName: ditert-butyl-(2-phenylphenyl)phosphane. Canonical SMILES: CC (C) (C)P (C1=CC=CC=C1C2=CC=CC=C2)C (C) (C)C. Density: 1 g/cm3. Catalog: ACM224311517-1.
2-O-Acetyl-3,4,6-tri-O-benzyl-b-D-glucopyranosyl trichloroacetimidate is a highly intricate and multifaceted chemical compound, finding its paramount utility within the sphere of glycoside research and development, natural compound research and development, and pharmaceutical intermediation. It has remarkable capacity to function as a recompound facilitating efficient and selective glycosidic linkage formation. Molecular formula: C31H32Cl3NO7. Mole weight: 636.95.
3-Dimethylaminopropyl-2-benzylaminobenzoate
3-Dimethylaminopropyl-2-benzylaminobenzoate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-[(Phenylmethyl)amino]benzoic acid 3-(Dimethylamino)propyl ester. CAS No. 87453-76-7. Pack Sizes: 100MG. IUPAC Name: 3-(dimethylamino)propyl 2-(benzylamino)benzoate. Molecular Formula: C19H24N2O2. Mole Weight: 312.41. Catalog: APS87453767. SMILES: CN(C)CCCOC(=O)c1ccccc1NCc2ccccc2. Format: Neat. Shipping: Room Temperature.
4-[2-(Dimethylamino)ethoxy]benzylamine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20059-73-8. Pack Sizes: 1G. IUPAC Name: 2-[4-(aminomethyl)phenoxy]-N,N-dimethylethanamine. Molecular Formula: C11H18N2O. Mole Weight: 194.27. Catalog: APS20059738. SMILES: CN(C)CCOc1ccc(CN)cc1. Format: Neat. Shipping: Room Temperature.
5-Benzyl Benzydamine Hydrochloride
5-Benzyl Benzydamine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2196183-71-6. IUPAC Name: 3-(1,5-dibenzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride. Molecular Formula: C26H29N3O.ClH. Mole Weight: 435.99. Catalog: APS2196183716. SMILES: Cl. CN (C)CCCOc1nn (Cc2ccccc2)c3ccc (Cc4ccccc4)cc13. Format: Neat.
alpha-[2-(Methylamino)ethyl]benzyl Alcohol
alpha-[2-(Methylamino)ethyl]benzyl Alcohol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Fluoxetine Hydrochloride Imp. A (EP),(1RS)-3-(Methylamino)-1-phenylpropan-1-ol. CAS No. 42142-52-9. Pack Sizes: 5G. IUPAC Name: 3-(methylamino)-1-phenylpropan-1-ol. Molecular Formula: C10H15NO. Mole Weight: 165.23. Catalog: APS42142529A. SMILES: CNCCC(O)c1ccccc1. Format: Neat. Shipping: Room Temperature.
Amylin (14-20) (human)
The formation of amyloid deposits by IAPP can play a central role in the pathogenesis of type 2 diabetes. In addition to the amyloidogenic 20-29 region, the NFLVHSS domain (IAPP 14-20) tends to aggregate and seems to be involved in plaque formation. Synonyms: H-Asn-Phe-Leu-Val-His-Ser-Ser-OH; L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-serine; (2S,5S,8S,11S,14S,17S,20S)-8-((1H-imidazol-4-yl)methyl)-20,22-diamino-17-benzyl-2,5-bis(hydroxymethyl)-14-isobutyl-11-isopropyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18-hexaazadocosan-1-oic acid. Grades: ≥95%. CAS No. 121341-77-3. Molecular formula: C36H54N10O11. Mole weight: 802.89.
Benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside
Benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a biomedical compound used for studying bacterial infections by inhibiting biofilm formation. Furthermore, it shows potential in cancer research as a novel glycosylation inhibitor, offering promising avenues for drug discovery and development. Synonyms: Benzyl 2-Acetamido-2-deoxy-beta-D-glucopyranoside; Benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside; CHEMBL1818656; N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-phenylmethoxyoxan-3-yl]acetamide; N-((2R,3R,4R,5S,6R)-2-(Benzyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide; SCHEMBL542635; DTXSID201236521; BDBM50466400; MFCD00070372; AKOS015910500; Benzyl 2-Acetamido-2-deoxy-?-D-glucopyranoside; Benzyl 2-Acetamido-2-deoxy- beta -D-glucopyranoside; b-D-Glucopyranoside,phenylmethyl2-(acetylamino)-2-deoxy-; Phenylmethyl 2-(acetylamino)-2-deoxy-beta-D-glucopyranoside; N-[(2R,3R,4R,5S,6R)-2-(BENZYLOXY)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-3-YL]ACETAMIDE. CAS No. 13343-67-4. Molecular formula: C15H21NO6. Mole weight: 311.33.
Benzyl 2-Chloroethyl Ether
Benzyl 2-Chloroethyl Ether is used in the synthesis of phosphane ligands with novel linker units that are complexed with rhodium to be used as building blocks for dendrimer catalysts. Also used in the formation of 2,6-diphenylpyrazine molecule derivatives which display cytotoxic properties. Group: Biochemicals. Alternative Names: Benzyl 2-chloroethyl Ether; 1-(Benzyloxy)-2-chloroethane; 2-Benzyloxy-1-chloroethane; 2-Phenylmethyloxyethyl Chloride; Benzyl 2-Chloroethyl Ether; NSC 11269; α-(2-Chloroethoxy)toluene. Grades: Highly Purified. CAS No. 17229-17-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
benzyl alcohol O-benzoyltransferase
The enzyme is involved in volatile benzenoid and benzoic acid biosynthesis. The enzyme from Petunia hybrida also catalyses the formation of 2-phenylethyl benzoate from benzoyl-CoA and 2-phenylethanol. The apparent catalytic efficiency of the enzyme from Petunia hybrida with benzoyl-CoA is almost 6-fold higher than with acetyl-CoA. Group: Enzymes. Synonyms: benzoyl-CoA:benzyl alcohol benzoyltransferase; benzoyl-CoA:benzyl alcohol/phenylethanol benzoyltransferase; benzoyl-coenzyme A:benzyl alcohol benzoyltransferase; benzoyl-coenzyme A:phenylethanol benzoyltransferase. Enzyme Commission Number: EC 2.3.1.196. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2139; benzyl alcohol O-benzoyltransferase; EC 2.3.1.196; benzoyl-CoA:benzyl alcohol benzoyltransferase; benzoyl-CoA:benzyl alcohol/phenylethanol benzoyltransferase; benzoyl-coenzyme A:benzyl alcohol benzoyltransferase; benzoyl-coenzyme A:phenylethanol benzoyltransferase. Cat No: EXWM-2139.
Benzylammonium Iodide
Benzylammonium Iodide. Uses: The iodide and bromide based alkylated halides find applications as precursors for fabrication of perovskites for photovoltaic applications.benzylammonium iodide can be used as an additive to improve the crystal formation of perovskites, which further facilitate an increase in the efficiency of solar cells. it can also be used in the formation of alkaline exchange membrane based fuel cells. Group: Perovskite materials. Alternative Names: Phenylmethylamine Iodide, greatcell Solar. Pack Sizes: 5 g/25 g. Product ID: benzylazanium; iodide. Molecular formula: 235.07 g/mol. Mole weight: C7H10IN. C1=CC=C(C=C1)C[NH3+].[I-]. InChI=1S/C7H9N. HI/c8-6-7-4-2-1-3-5-7; /h1-5H, 6, 8H2; 1H. PPCHYMCMRUGLHR-UHFFFAOYSA-N.
Benzyl butyl phthalate
Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 85-68-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W011338.
Benzyl butyl phthalate-d4
Benzyl butyl phthalate-d 4 is the deuterium labeled Benzyl butyl phthalate[1]. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs)[2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 93951-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W011338S.
Benzyl Phenylephrone Hydrochloride
Benzyl Phenylephrone Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71786-67-9. IUPAC Name: 2-[benzyl(methyl)amino]-1-(3-hydroxyphenyl)ethanone;hydrochloride. Molecular Formula: C16H17NO2.ClH. Mole Weight: 291.77. Catalog: APS71786679. SMILES: Cl.CN(CC(=O)c1cccc(O)c1)Cc2ccccc2. Format: Neat.
β-primeverosidase
The enzyme is responsible for the formation of the alcoholic aroma in oolong and black tea. In addition to β-primeverosides [i.e. 6-O-(β-D-xylopyranosyl)-β-D-glucopyranosides], it also hydrolyses 6-O-(β-D-apiofuranosyl)-β-D-glucopyranosides and, less rapidly, β-vicianosides and 6-O-(α-L-arabinofuranosyl)-β-D-glucopyranosides, but not β-glucosides. Geranyl-, linaloyl-, benzyl- and p-nitrophenol glycosides are all hydrolysed. Group: Enzymes. Enzyme Commission Number: EC 3.2.1.149. CAS No. 884593-92-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3831; β-primeverosidase; EC 3.2.1.149; 884593-92-4. Cat No: EXWM-3831.
CAP 3
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. CAP 3 inhibits E. coli biofilm formation on catheters implanted in mice infected with E. coli at the incision site when applied as a coating on the catheters. CAP 3 (40 mg/kg) also reduces bacterial load in E. coli-infected wounds in mice. It is cytotoxic to A459 cells (IC50 = 56.4 μM) and has hemolytic activity against human red blood cells with a 50% lysis (HC50) value of 48 μM. Synonyms: CAP 3; CHEMBL5173640; benzyl (4R)-4-[(3R, 5S, 7R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 7, 12-tris[[2-[(2-amino-3-methylbutanoyl)amino]acetyl]oxy]-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Grades: ≥98%. Molecular formula: C52H82N6O11. Mole weight: 967.3.
Cathepsin L Inhibitor
Cathepsin L inhibitor is a potent inhibitor of cathepsin L with IC50 of 0.85 nM. It is trypanocidal with an ED50 value of 45 nM against T. brucei that is well below the ED50 value of 21,500 nM for human HL-60 cells. In vivo, cathepsin L inhibitor (2.5-10 mg/kg) inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner. Cathepsin L inhibitor can also completely suppress osteoclastic pit formation on femur slices isolated from bovine cortical bone. Synonyms: Z-FY-CHO; Z-Phe-Tyr-aldehyde; SB 412515; N-(benzyloxycarbonyl)-phenylalanyl-l-tyrosinal. Grades: ≥95%. CAS No. 167498-29-5. Molecular formula: C26H26N2O5. Mole weight: 446.49.
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons. Synonyms: CK 0106023; CK-0106023; N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide. CAS No. 336115-72-1. Molecular formula: C30H32BrClN4O2. Mole weight: 595.97.
Defluoro N-Benzyl Paroxetine Hydrochloride
Defluoro N-Benzyl Paroxetine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS001460. Format: Neat.
Denatonium-d5 Benzoate (benzyl-2,3,4,5,6-d5)
Denatonium-d5 Benzoate (benzyl-2,3,4,5,6-d5). Uses: For analytical and research use. Group: Food additives, flavours & adulterants. Catalog: APS001469. Format: Neat.
Methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-a-D-galactopyranoside, an essential compound in the field of biomedicine, showcases immense potential as an intermediate or reagent during carbohydrate synthesis, glycosylation, and the formation of glycoconjugates. Its distinctive structure facilitates the creation of pharmaceuticals tailored to combat disorders associated with carbohydrate metabolism and signaling pathways. CAS No. 862730-60-7. Molecular formula: C34H46O6Si. Mole weight: 578.83.
Methyl 4,6-O-benzylidene-2,3-di-O-pivaloyl-a-D-mannopyranoside is a pivotal constituent in biomedical applications, aiding in the research of carbohydrate-based diseases. Distinguished for its commendable suitability as a precursor, it instigates the formation of compounds that impeccably study afflictions such as cancer, inflammation and infections. Molecular formula: C24H34O8. Mole weight: 450.53.
N-(3-Chloro-benzyl) Econazole Chloride
N-(3-Chloro-benzyl) Econazole Chloride. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002398. Format: Neat.
Native Escherichia coli Penicillin Amidase
The biosynthesis of Penicillin amidase in E. coli by hydrophobic protein chromatography is an inducible reaction which is regulated by metabolized carbon source (e.g. polyols, carboxylic acid etc.). It is also influenced by catabolite repression. It catalyzes the formation of amide bonds through an acyl-enzyme intermediate. Penicillin amidase is a periplasmic 80k heterodimer with a and b chains (209 and 566 amino acids, respectively). it is widely distributed among microorganisms, including bacteria, yeast and filamentous fungi. among all the sources, the enzyme produced by e. coli is most well-characterized and common for industrial application. Applications: Penicillin...; benzylpenicillin acylase; novozym 217; semacylase; α-acylamino-β-lactam acylhydrolase; ampicillin acylase; EC 3.5.1.11; 9014-06-6. Enzyme Commission Number: EC 3.5.1.11. CAS No. 9014-6-6. Penicillin Amidase. Mole weight: Mr ~70 kDa. Activity: Type I, 5-10 units/mg protein; Type II, > 10 units/mg protein (E1%/280). Storage: 2-8°C. Form: Type II, ammonium sulfate suspension, Suspension in 0.1 M phosphate, pH 7.5 and 3 M ammonium sulfate. Source: Escherichia coli. penicillin amidase; penicillin acylase; benzylpenicillin acylase; novozym 217; semacylase; α-acylamino-β-lactam acylhydrolase; ampicillin acylase; EC 3.5.1.11; 9014-06-6. Cat No: NATE-0541.
N-Benzyl Carvedilol
N-Benzyl Carvedilol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 72955-94-3. Pack Sizes: 25MG. IUPAC Name: 1-[benzyl-[2-(2-methoxyphenoxy)ethyl]amino]-3-(9H-carbazol-4-yloxy)propan-2-ol. Molecular Formula: C31H32N2O4. Mole Weight: 496.60. Catalog: APS72955943B. SMILES: COc1ccccc1OCCN (CC (O) COc2cccc3[nH]c4ccccc4c23) Cc5ccccc5. Format: Neat. Shipping: Room Temperature.
N-Benzyl Epinephrine
N-Benzyl Epinephrine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: rac Adrenaline EP Impurity D. CAS No. 1095714-91-2. Pack Sizes: 10MG. IUPAC Name: 4-[2-[benzyl(methyl)amino]-1-hydroxy-ethyl]benzene-1,2-diol. Molecular Formula: C16H19NO3. Mole Weight: 273.33. Catalog: APS1095714912. SMILES: CN(CC(O)c1ccc(O)c(O)c1)Cc2ccccc2. Format: Neat. Shipping: Room Temperature.
N-Benzyl Epinephrine-d3
N-Benzyl Epinephrine-d3. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS010275. Format: Neat. Shipping: Room Temperature.
N-Benzyl-N-(2-chloroethoxy)-1-phenylmethanamine
N-Benzyl-N-(2-chloroethoxy)-1-phenylmethanamine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-Benzyl-N-(2-chloroethoxy)-1-phenylmethanamine. IUPAC Name: N-benzyl-N-(2-chloroethoxy)-1-phenylmethanamine. Molecular Formula: C16H18ClNO. Mole Weight: 275.77. Catalog: APS010276. SMILES: ClCCON(Cc1ccccc1)Cc2ccccc2. Format: Neat. Shipping: Room Temperature.
ONO-1301
ONO-1301, a naphthalen derivative, has been found to be a prostacyclin agonist and could be studied as an anti-inflammatory agent works partially through leading the formation of hepatocyte growth factor. Synonyms: Ono1301; Ono-1301; Ono 1301; 7,8-Dihydro-5-[(E)-[[-(3-pyridyl)benzylidene]aminooxy]ethyl]-1-naphthyloxy]acetic acid. Grades: 98%. CAS No. 176391-41-6. Molecular formula: C27H26N2O4. Mole weight: 428.48.
Intermediate in the preparation of trifluoro methyl diazirine, useful as a photo-induced cross-linking probe for exploring amyloid formation. Group: Biochemicals. Alternative Names: 1- [4- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] phenyl] -2, 2, 2-trifluoro-ethanone. Grades: Highly Purified. CAS No. 87736-75-2. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
(Oxybis(2,1-phenylene))bis(diphenylphosphine)
Useful as a ligand in the Pd-catalyzed formation of diaryl amines. Has been recently applied to the C3 benzylation of indoles. Has been recently applied to the monoallylation of ammonia. Ligand used in the palladium-catalyzed, aerobic oxidation coupling of acyl chlorides with arylboronic acids. Ligand used in carbonylation of aryl iodides. Ligand used in the direct C-H arylation of benzothiodiazoles. Ligand used in stereo-retentive azacyclization of propargylic carbonates. Ligand used in palladium catalyzed benzyne trimerization. Group: Organic phosphine compounds. CAS No. 166330-10-5. Molecular formula: C36H28OP2. Mole weight: 538.567g/mol. IUPACName: [2- (2-diphenylphosphanylphenoxy) phenyl]-diphenylphosphane. Canonical SMILES: C1=CC=C (C=C1) P (C2=CC=CC=C2) C3=CC=CC=C3OC4=CC=CC=C4P (C5=CC=CC=C5) C6=CC=CC=C6. Catalog: ACM166330105.
Penicillin G, Sodium Salt USP
Penicillin G is a broad based antibiotic used in mammalian cell culture. Penicillin G blocks the formation of bacterial cell walls, rendering bacteria unable to multiply and spread. The spectrum of activity of Penicillin G includes many aerobic and anaerobic gram-positive organisms. Aerobes susceptible to Penicillin G include most beta-hemolytic streptococci, beta-lactamase-negative staphylococci, Actinomyces species, some Bacillus anthracis, Corynebacterium species, and Erysipelothrix rhusiopathiae. Most species of anaerobes, including Clostridium species, but excluding beta-lactamase-producing Bacteroides species, are also susceptible to Penicillin G. Penicillin G is easily ...id Monosodium Salt; (2S, 5R, 6R)-3, 3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid Monosodium Salt; American Penicillin; Benzylpenicillin Sodium; Benzylpenicillin Sodium Salt; Benzylpenicillinic Acid Sodium Salt; Crystapen; Ethacillin; Monocillin; Monosodium Benzylpenicillin; Mycofarm; Nalpen G; Nobak; Novocillin; Pen-A-Brasive; Penicillin G Sodium; Penilaryn; Sodium 6- (Phenylacetamido) penicillanate; Sodium Benzylpenicillin; Sodium Benzylpenicillin G; Sodium Benzylpenicillinate. Grades: USP. CAS No. 69-57-8. Pack Sizes: 50g, 100g, 500g, 1Kg. Molecular Formula: C16H17N2O4NaS, Molecular Weight: 356.37. US Biological Life Sciences.
Worldwide
Pentoxifylline EP Impurity I
An impurity of Pentoxifylline which improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Synonyms: 1-Benzyltheobromine; 55247-90-0; 1-Benzyl-3,7-dimethylxanthine; 1-benzyl-3,7-dimethylpurine-2,6-dione; 8RUV41LJ96; Pentoxifylline Impurity I; UNII-8RUV41LJ96; Pentoxifylline impurity I [EP]; 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(phenylmethyl)-; 1-Benzyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 3,7-Dihydro-3,7-dimethyl-1-(phenylmethyl)-1H-purine-2,6-dione; AC1LEVEQ; SMR000091572; ChemDiv2_003332; Cambridge id 5356026; Oprea1_050581; Oprea1_707161; MLS000114126; CHEMBL1883787; SCHEMBL10394509; DTXSID70353474; HMS1378H10; HMS2241F19; AKOS025151071; PENTOXIFYLLINE IMPURITY I [EP IMPURITY]; AB00082638-01; 1-benzyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. CAS No. 55247-90-0. Molecular formula: C14H14N4O2. Mole weight: 270.29.
Polymyxin B Sulfate
Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixture of Polymyxin B1 and B2 sulfate. Group: Biochemicals. Alternative Names: N- [3-Amino-1- [ [1- [ [3-amino-1- [ [6, 9, 18-tris (2-aminoethyl) -15-benzyl-3- (1-hydroxyethyl) -12- (2-methylpropyl) -2, 5, 8, 11, 14, 17, 20-heptaoxo-1, 4, 7, 10, 13, 16, 19-heptazacyclotricos-21-yl] carbamoyl] propyl] carbamoyl] -2-hydroxy-propyl] carbamoyl] propyl] -6-methyl-octanamide Sulfuric Acid. Grades: Highly Purified. CAS No. 1405-20-5. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Ponesimod
Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented t...tal drug for the treatment of multiple sclerosis (ms) and psoriasis. Synonyms: ACT-128800; ACT 128800; ACT128800; Ponesimod. (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one;4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]Methylene]-3-(2-Methylphenyl)-2-(propyliMino)-, (2Z,5Z)-;ACT-128800;5-[3-Chloro-4-[((2R)-2,3-dihydroxypropyl)oxy]benz-(Z)-ylidene]-2-((Z)-propylimino)-3-(o-tolyl)thiazolidin-4-one;(5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one. Grades: ≥ 95.0%. CAS No. 854107-55-4. Molecular formula: C23H25ClN2O4S. Mole weight: 460.97.
Alkoxymethyltrifluoroborate undergoes palladium-catalyzed carbon-carbon bond formation (Suzuki-Miyuara reaction) with aryl chlorides to provide a non-traditional disconnection for the preparation of aryl- and heteroaryl ethers. Synonyms: Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate. Grades: 95 %. CAS No. 1027642-26-7. Molecular formula: C9H11BF3KO2. Mole weight: 258.087.
A cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC50=27.4uM). Does not affect RecA even at much higher concentration (~250uM). Directly interacts with RAD51 (=5.6uM), and disrupts its binding to DNA and nucleoprotein filament formation. Blocks double-strand break-induced homologous recombination and enhances sensitivity of cells to Cisplatin and Mitomycin C. Diminishes co-aggregate formation between RAD51-ssDNA filament and dsDNA. RAD51-Stimulatory Compound-1, RS-1 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
(R)-SITCP
Phosphine-catalyzed intra-and intermolecular gamma-addition of nitrogen nucleophiles to allenoates and alkynoates. Catalytic asymmetric construction of the tryptanthrin skeleton via enantioselective decarboxylative [4+2] cyclization. Catalytic, enantioselective carbon-oxygen bond formation - phosphine-catalyzed synthesis of benzylic esters via oxidation of benzylic C-H bonds. Use of a new spirophosphine to achieve catalytic, enantioselective [4+1] annulations of amines with allenes to generate dihydropyrroles. Group: Heterocyclic organic compound. Alternative Names: (R)-SITCP; CS-212; (S)-(-)-SITCP; 5-Phenyl-5,6,10,11,12,13-hexahydro-4H-diindeno[7,1-cd:1\',7\'-ef]ph osphocine; AB1005819; (11aR)-(+)-5,6,10,11,12,13-Hexahydro-5-phenyl-4H-diindeno[7,1-cd; CS-0037626; CS-0037625; (S)-dimethylene-[7,7 inverted exclamation marka-(1,1 inverted exclamation marka-spiroindan)]-phenylphospholane; 7, 7'-(Phenylphosphinediylbismethylene)-1, 1'-spirobiindan. CAS No. 856407-37-9. Molecular formula: C25H23P. Mole weight: 354.433g/mol. IUPACName: 10-phenyl-10-phosphapentacyclo[10.6.1.11, 4.016, 19.08, 20]icosa-4(20), 5, 7, 12, 14, 16(19)-hexaene. Canonical SMILES: C1CC23CCC4=C2C (=CC=C4)CP (CC5=CC=CC1=C35)C6=CC=CC=C6. Catalog: ACM856407379.
(S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine. Uses: Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures. asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines. nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes. enantioselective reduction of prochiral ketones with nabh4/me2so4/(s)-me-cbs. Group: other electronic materials. Alternative Names: AKOS015840981; (S)-1-methyl-3,3-diphenyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; MFCD00078439; (S)- Methyl-CBS-oxazaborolidine; ZINC169743318; (S)-tetrahydro-1-methyl-3,3-diphenyl-1 H,3 H-pyrrolo[1,2-c][1,3,2] oxazaborole; (S)-1-methyl-3,3-diphenylhexahydropyrrolo-[1,2-c][1,3,2]oxazaborole; (S)-tetrahydro-1-methyl-3,3-diphenyl-1 H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole; (S)-Me-CBS; Corey catalyst. CAS No. 112022-81-8. Product ID: (3aS)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole. Molecular formula: 277.174g/mol. Mole weight: C18H20BNO. B1 (N2CCCC2C (O1) (C3=CC=CC=C3)C4=CC=CC=C4)C. InChI=1S / C18H20BNO / c1-19-20-14-8-13-17 (20) 18 (21-19, 15-9-4-2-5-10-15) 16-11-6-3-7-12-16 / h2-7, 9-12, 17H, 8, 13-14H2, 1H3 / t17- / m0 / s1. VMKAFJQFKBASMU-KRWDZBQOSA-N.
Survivin Inhibitor III, LLP-3 (Survivin-Ran Interaction Blocker, LLP3, 4-(3,5-bis(Benzyloxy)phenyl)-6-(5-chloro-2-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile)
A cell-permeable, dihydropyridinone compound that selectively disrupts survivin-Ran interaction in cell-free binding assays (IC50 <0.3uM) and in U87 glioma cells (by 55% in 24h; 20uM) via direct binding at survivin protein-protein interaction interface, while exhibiting much reduced or little potency against survivin-Smac/DIABLO, survivin-survivin, or XIAP-Smac/DIABLO interaction. LLP-3 treatment abrogates neurosphere formation in GMB cultures (IC50 ≤35uM) by selectively depleting CD133+ GSC population via apoptosis induction. TMZ, in comparison, enriches GMB GSC population by preferentially eradicating non-GSC population. LLP-3 is also efficacious in treating human GMB xenograft in mice in vivo (25mg/kg/day via i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Teclozan
Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti- G. intestinalis. Teclozan can be used for the research of protozoan infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WIN 13146. CAS No. 5560-78-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19594.
Tri(2-furyl)phosphine
Useful ligand for C-C coupling reactions. Ligand used for the alkynylation of thioesters. Ligand used for enol ester formation. Ligand for palladium-catalyzed 3-Component coupling. Ligand for palladium-catalyzed C-C coupling reaction. Ligand for trans-olefin formation. Olefin formation from N-tosylhydrazones and benzyl halides. C-H arylation/alkenylation of 1-substituted tetrazoles. Group: Organic phosphine compounds. Alternative Names: Trifurylphosphine. CAS No. 5518-52-5. Molecular formula: C12H9O3P. Mole weight: 232.17. Appearance: Solid. Purity: 0.98. IUPACName: tris(furan-2-yl)phosphane. Canonical SMILES: C1=COC(=C1)P(C2=CC=CO2)C3=CC=CO3. Catalog: ACM5518525-1.
VJ115
VJ115 is a novel chemical entity that inhibits the enzyme ENOX1, a NADH oxidase. Genetic and small molecule inhibition of ENOX1 inhibits endothelial cell tubule formation and tumor-mediated neo-angiogenesis. VJ115 inhibition of ENOX1 can impact expression of proteins involved in cytoskeletal reorganization and support a hypothesis in which ENOX1 activity links elevated cellular NADH concentrations with cytoskeletal reorganization and angiogenesis. Synonyms: VJ 115; VJ-115; (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)quinuclidin-3-ol. CAS No. 929256-79-1. Molecular formula: C23H24N2O. Mole weight: 344.45.
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