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| Product | Description | |
|---|---|---|
| Calcium formate | Calcium formate is the calcium salt of formic acid. It is also known as food additive E238 in food industry. The mineral form is very rare and called formicaite. It is known from a few boron deposits. It may be produced synthetically by reacting calcium oxide or calcium hydroxide with formic acid. Synonyms: Calcium diformate; Calcoform. Grades: 98%. CAS No. 544-17-2. |  |
| Calcium Formate | Calcium Formate. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. |  California |
| Calcium Formate 544-17-2 | Calcium Formate - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Calcium Formate Food Grade | Calcium Formate Food Grade. |  CA, FL & NJ |
| A 438079 | A potent, competitive, and selective antagonist of P2X7 purinergic receptor (pIC50 = 6.5nM and 6.9nM for rat and human P2X7 receptor, respectively). Shown to reduce ATP-induced reactive oxygen species formation in MEL cells by about 87% (~10uM) and blocks BzATP-stimulated changes in intracellular calcium concentrations (IC50 = 100 and 300nM at rat and human P2X7 receptors, respectively. Developed by Abbott. Group: Biochemicals. Alternative Names: 3-((5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine Hydrochloride; P2X7 Purinergic Receptor Antagonist; A 438079; A438079; A-438079. Grades: Highly Purified. CAS No. 899507-36-9. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N? HCl, Molecular Weight: DMSO. US Biological Life Sciences. |  Worldwide |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Synonyms: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. Grades: >98 %. CAS No. 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. | |
| Acid Blue 3 calcium | Acid Blue 3 calcium. Uses: For analytical and research use. Group: Dyes & metabolites; dyes & metabolites. Alternative Names: E 131 Patent Blue, Patent Blue V Sodium Salt 36001, C.I. Food Blue 5, C.I. Acid Blue 3, Solar Pure Blue VX, Patent Blue, Patent Blue V Carmine Blue V, Carmine Blue V, Vitasyn Patent Blue V 85, New Patent Blue A-CE Extra, C.I. Acid Blue 3 calcium salt (2:1), Sicovit Patent Blue 85E131, Blue ZN 3, New Patent Blue Extra Pure A, Dai-ei Acid Pure Blue VX, Merantine Blue V, Patent Blue V Calcium Salt 90146, Acid Blue 3,N-[4-[[4-(Diethylamino)phenyl](5-hydroxy-2,4-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethylethanaminium inner salt calcium salt (2:1...ohexadien-1-ylidene]-N-ethylethanaminium hydroxide inner salt calcium salt (2:1), Patent Blue V, Food Blue 5, Mitsui Acid Pure Blue VX, E 131, Patent Blue V Calcium Salt 36017, Ariavit Patent Blue V. CAS No. 3536-49-0. IUPAC Name: calcium;4-[[4-(diethylamino)phenyl]-(4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]-6-hydroxybenzene-1,3-disulfonate. Molecular Formula: 2C27H31N2O7S2.Ca. Mole Weight: 1159.43. Catalog: APS3536490. SMILES: [Ca+2]. CCN (CC)c1ccc (cc1)C (=C2C=CC (=[N+] (CC)CC)C=C2)c3cc (O)c (cc3S (=O) (=O)[O-])S (=O) (=O)[O-]. CCN (CC)c4ccc (cc4)C (=C5C=CC (=[N+] (CC)CC)C=C5)c6cc (O)c (cc6S (=O) (=O)[O-])S (=O) (=O)[O-]. Format: Neat. Shipping: Room Temperature. |  |
| Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010) | Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease. Group: Biochemicals. Alternative Names: Antibiotic TAN 1364B, Antibiotic CI 010. Grades: Highly Purified. CAS No. 154639-24-4(TAN1364B). Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Atorvastatin Epoxydione Impurity | Atorvastatin Epoxydione Impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Atorvastatin USP RC D, Atorvastatin USP Related Compound D, Atorvastatin Imp. D (EP), 3-[(4-Fluorophenyl)carbonyl]-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide,Atorvastatin Calcium Trihydrate Imp. D (EP). CAS No. 148146-51-4. IUPAC Name: 3-(4-fluorobenzoyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide. Molecular Formula: C26H22FNO4. Mole Weight: 431.46. Catalog: APS148146514. SMILES: CC (C)C (=O)C1 (OC1 (C (=O)c2ccc (F)cc2)c3ccccc3)C (=O)Nc4ccccc4. Format: Neat. | |
| Atractyloside, Calcium Salt | Atractyloside Calcium Salt is a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. Atractyloside induces the release of ahyaluronidase-induced murine WW domain-containing oxidoreductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity. Group: Biochemicals. Alternative Names: (2 β,15α)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo- β-D-glucopyranosyl]oxy]-19-Norkaur-16-en-18-oic Acid Calcium Salt; 19-Norkaur-16-en-18-oic acid deriv. 1H-2,10a-Ethanophenanthrene Calcium Salt. Grades: Highly Purified. CAS No. 772298-35-8 free acid. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Bovine Protein C | The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag...g the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. Purity: >95% by SDS-PAGE. Prote |  |
| Calcitonin (salmon) | Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Uses: Scientific research. Group: Peptides. Alternative Names: Salmon calcitonin. CAS No. 47931-85-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0090. |  |
| Calpain Inhibitor VI | Calpain Inhibitor VI is a cell-permeable peptide aldehyde which functions as a reversible calpain inhibitor. It is an inhibitor of the calcium-dependent cysteine proteases μ-calpain with IC50 of 7.5 nM for calpain-1 and m-calpain with IC50 of 78 nM for calpain-2. Calpain Inhibitor VI can reduce nuclear opacity and proteolysis of crystallins and α-spectrin. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Synonyms: SJA 6017. Grades: ≥95%. CAS No. 190274-53-4. Molecular formula: C17H25FN2O4S. Mole weight: 372.5. | |
| Chlorobutanol | Chlorobutanol is an orally active and potent inhibitor of platelet aggregation and release and a pharmaceutical preservative with antibacterial activity. Chlorobutanol inhibits thromboxane B2 formation, ATP release, and elevation of cytosolic free calcium caused by collagen, ADP, epinephrine, arachidonic acid and thrombin. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria , and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57-15-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1263. | |
| Citropin-1.1 | Citropin-1.1 is isolated from Litoria citropa. It has bacteriostatic action for Gram-positive bacteria. Citropin-1.1 strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations. It acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS. Molecular formula: C76H131N19O19. Mole weight: 1614.96. | |
| CK 1827452 | CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins. It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP. It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure. Group: Biochemicals. Alternative Names: Methyl 4- [ [2-Fluoro-3- [N'- (6-methylpyridin-3-yl) ureido] phenyl] methyl] piperazine-1-carboxylate; 4- [ [2-Fluoro-3- [ [ [ (6-methyl-3-pyridinyl) amino] carbonyl] amino] phenyl] methyl] -1-piperazinecarboxylic Acid Methyl Ester; Omecamtiv Mecarbil. Grades: Highly Purified. CAS No. 873697-71-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 401.43. US Biological Life Sciences. | Worldwide |
| Clodronate | Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. Uses: Bone density conservation agents. Synonyms: Clodronic Acid; Acido clodronico; Dichloromethylidene diphosphonate; dichloromethylene-1,1-diphosphonic acid; Dichlormethylen-bis(phosphonsaeure). Grades: >98%. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. | |
| D-Mannitol | D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β 3 -adrenergic receptor ( β 3 -AR ), PGC1α and PKA induced by means of white fat cells into brown fat cells [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Mannitol; Mannite. CAS No. 69-65-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-N0378. | |
| D-Mannitol (Standard) | D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Mannitol(Standard); Mannite (Standard). CAS No. 69-65-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0378R. | |
| Fenoprofen calcium | Fenoprofen calcium. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites. Alternative Names: Benzeneacetic acid, α-methyl-3-phenoxy-, calcium salt (9CI), 2-(3-Phenoxyphenyl)propionic acid calcium salt, Nalfon, Fenoprofen calcium, Calcium fenoprofen,Benzeneacetic acid, α-methyl-3-phenoxy-, calcium salt (2:1), Trandor, Benzeneacetic acid, α-methyl-3-phenoxy-, calcium salt, (±)-. CAS No. 34597-40-5. IUPAC Name: calcium;2-(3-phenoxyphenyl)propanoate. Molecular Formula: 2C15H13O3.Ca. Mole Weight: 522.60. Catalog: APS34597405. SMILES: [Ca+2].CC(C(=O)[O-])c1cccc(Oc2ccccc2)c1.CC(C(=O)[O-])c3cccc(Oc4ccccc4)c3. Format: Neat. Shipping: Room Temperature. | |
| Heparin sodium salt (Low in Ca) | Heparin sodium salt (Low in Ca) is a bioactive compound with potent anticoagulant properties that are essential in managing various blood clotting disorders, including deep vein thrombosis and pulmonary embolisms. Its unique mechanism of action involves the inhibition of blood clot formation, effectively reducing the risk of further complications. This specialized Heparin sodium salt formulation contains reduced levels of calcium, thus minimizing the potential incidence of the dreaded heparin-induced thrombocytopenia (HIT) syndrome. Complex yet highly effective, this anticoagulant therapy represents a crucial medical breakthrough in ensuring patient safety and well-being. | |
| Human Protein C | The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag...ng the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. CAS No. 42617-41-4. Purity: >95 | |
| Inorganic Pyrophosphatase from Escherichia coli, Recombinant | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. Applications: Inorganic pyrophosphatase (ppase) is a ubiquitous enzyme catalyzing the reaction ppi + h2o ? 2pi. it plays an important role in protein, rna, and dna synthesis. Group: Enzymes. Synonyms: Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.1. CAS No. 9024-82-2. Purity: > 90%. Inorganic pyrophosphatase. Activity: > 800 units/mg protein. Storage: -20°C. Form: Lyophilized powder in Tris-buffered salts containing protease inhibitors. Source: E. coli. Species: Escherichia coli. Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-0355. | |
| Inorganic Pyrophosphatase from Saccharomyces cerevisiae, Recombinant | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. Inorganic pyrophosphatase (ppase) catalyzes the hydrolysis of inorganic pyrophosphate to form orthophosphate. a variety ...actions that can be pulled far in the synthesis direction by the action of inorganic pyrophosphatase. Applications: Enhancing yields of rna in transcription reactions. Group: Enzymes. Synonyms: Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. CAS No. 9024-82-2. Inorganic pyrophosphatase. Mole weight: 71 kDa. Storage: at -20°C. Form: 20 mM Tris-HCl (pH 8.0), 100 mM KCl, 0.1 mM EDTA, 1 mM dithiothreitol and 50% glycerol. Source: E. coli. Species: Saccharomyces cerevisiae. Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-1281. | |
| L-Lysine hydrate | L-Lysine is a nutritional supplement containing the biologically active L-isomer of the essential amino acid lysine, with potential anti-mucositis activity. Upon oral intake, L-lysine promotes healthy tissue function, growth and healing and improves the immune system. L-Lysine promotes calcium uptake, is essential for carnitine production and collagen formation. As collagen is essential for connective tissue maintenance, this agent may also help heal mucosal wounds. This may help decrease and prevent mucositis induced by radiation or chemotherapy. Synonyms: L-Lys-OH H2O; (S)-2,6-Diaminohexanoic acid monohydrate; L-Lysine monohydrate; Lysine monohydrate; L(+)-Lysine monohydrate; L-Lysine, hydrate; (2S)-2,6-diaminohexanoic acid hydrate; L Lys OH H2O. Grades: ≥ 99% (Titration). CAS No. 39665-12-8. Molecular formula: C6H14N2O2·H2O. Mole weight: 164.20. | |
| m-3M3FBS | m-3M3FBS is a direct activator of phospholipase C (PLC) that stimulates the increase in cytoplasmic calcium, inositol phosphate formation and superoxide generation in a variety of cell types. It is used in biological studies on Ca2+ homeostasis independently of phospholipase C activation. It is also used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122. It has also been used for intracellular calcium analysis and MAP kinase assay in 293T cells. It also inhibits growth of the leukemic cell lines U937 and THP-1. Synonyms: m-3M3FBS; m 3M3FBS; m3M3FBS; 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide; N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide. Grades: ≥99% by HPLC. CAS No. 200933-14-8. Molecular formula: C16H16F3NO2S. Mole weight: 343.36. | |
| myeloperoxidase | Contains calcium and covalently bound heme (proximal ligand histidine). It is present in phagosomes of neutrophils and monocytes, where the hypochlorite produced is strongly bactericidal. It differs from EC 1.11.1.10 chloride peroxidase in its preference for formation of hypochlorite over the chlorination of organic substrates under physiological conditions (pH 5-8). Hypochlorite in turn forms a number of antimicrobial products (Cl2, chloramines, hydroxyl radical, singlet oxygen). MPO also oxidizes bromide, iodide and thiocyanate. In the absence of halides, it oxidizes phenols and has a moderate peroxygenase activity toward styrene. Group: Enzymes. Synonyms: MPO; verdoperoxidase. Enzyme Commission Number: EC 1.11.2.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0513; myeloperoxidase; EC 1.11.2.2; MPO; verdoperoxidase. Cat No: EXWM-0513. | |
| Native Bacillus stearothermophilus Inorganic Pyrophosphatase | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. Applications: Inorganic pyrophosphatase (ppase) is a ubiquitous enzyme catalyzing the reaction ppi + h2o ? 2pi. it plays an important role in protein, rna, and dna synthesis. Group: Enzymes. Synonyms: Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.1. CAS No. 9024-82-2. Inorganic pyrophosphatase. Activity: 15-25 units/mg protein (biuret). Storage: 2-8°C. Form: lyophilized powder. Source: Bacillus stearothermophilus. Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-0353. | |
| Native Bacillus thermoproteolyticus Thermolysin | Thermolysin is a thermostable neutral metalloproteinase enzyme produced by the Gram-positive bacteria Bacillus thermoproteolyticus. It requires one zinc ion for enzyme activity and four calcium ions for structural stability. Thermolysin specifically catalyzes the hydrolysis of peptide bonds containing hydrophobic amino acids. However thermolysin is also widely used for peptide bond formation through the reverse reaction of hydrolysis. Thermolysin is the most stable member of a family of metalloproteinases produced by various Bacillus species. These enzymes are also termed 'neutral' proteinases or thermolysin-like proteinases (TLPs). Group: Enzymes. Synonyms: thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Enzyme Commission Number: EC 3.4.24.27. CAS No. 9073-78-3. TLN. Mole weight: 36.2kDa. Activity: Reverse-phase HPLC analysis shows <30% of undigested insulin after 10 minutes of incubation with Thermolysin at 75°C using a 1:20 thermolysin:insulin ratio. Form: Lyophilized. Source: Bacillus thermoproteolyticus. thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Cat No: NATE-0705. | |
| Native Baker's yeast (S. cerevisiae) Inorganic Pyrophosphatase | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. This ubiquitous enzyme serves to drive metabolic reactions that produce pyrophosphate, since these reactions typically have...phohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.1. CAS No. 9024-82-2. Inorganic pyrophosphatase. Mole weight: 71 kDa (homodimer consisting of two equal subunits of molecular weight 32-35 kDa). Activity: Type I, > 1,000 units/mg protein (BCA); Type II, > 500 units/mg protein (E1%/280). Storage: -20°C. Form: Type I, lyophilized powder containing 90% buffer salts; Type II, Lyophilized powder containing 85% buffer salts. Source: Baker's yeast (S. cerevisiae). Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-0354. | |
| Native E. coli Inorganic Pyrophosphatase | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. Applications: Increasing rna yield in transcription reaction; enhancing dna replication. Group: Enzymes. Synonyms: Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. CAS No. 9024-82-2. Inorganic pyrophosphatase. Form: 20 mM Tris-HCl, 100 mM NaCl, 1 mM Dithiothreitol, 0.1 mM EDTA, 50% Glycerol, pH 8.0 25°C. Store at -20°C. Source: E. coli. Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-1272. | |
| Native Geobacillus stearothermophilus Thermolysin | Thermolysin is a thermostable neutral metalloproteinase enzyme produced by the Gram-positive bacteria Bacillus thermoproteolyticus. It requires one zinc ion for enzyme activity and four calcium ions for structural stability. Thermolysin specifically catalyzes the hydrolysis of peptide bonds containing hydrophobic amino acids. However thermolysin is also widely used for peptide bond formation through the reverse reaction of hydrolysis. Thermolysin is the most stable member of a family of metalloproteinases produced by various Bacillus species. These enzymes are also termed 'neutral' proteinases or thermolysin-like proteinases (TLPs). Suitable for cell culture. Applica... of n-terminal to phe which is preferred over the others. often used to do limited proteolysis for peptide mapping and studies of protein structure and conformational changes. Group: Enzymes. Synonyms: thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Enzyme Commission Number: EC 3.4.24.27. CAS No. 9073-78-3. TLN. Activity: 30-175 units/mg protein (E1%/280). Storage: -20°C. Form: lyophilized powder containing calcium and sodium acetate buffer salts. Source: Geobacillus stearothermophilus. thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Cat No: NATE-0704. | |
| Native Guinea pig Transglutaminase | Transglutaminase from guinea pig liver consists of a single polypeptide chain of 691 amino acid residues. It has six potential glycosylation sites (Asn-X-Ser or Asn-X-Thr), but it is not glycosylated. The molecular mass is approximately 76.6 kDa. It is calcium dependent and has several calcium binding sites. The enzyme is inhibited by iodoacetamide and N-ethylmaleimide in the presence of calcium. It catalyzes the incorporation of small molecular weight amines into γ-glutamine sites of proteins. In the absence of small molecular weight amines, it catalyzes the cross linking of proteins that results in the formation of γ-glutamyl-ε-lysine side chain peptide...h as huntington?s disease and alzheimer?s disease.transglutaminase has also been used in a study to develop a nonradioactive dot blot assay for transglutaminase activity. Group: Enzymes. Synonyms: transglutaminase; EC 2.3.2.13; 80146-85-6; transglutaminase; Factor XIIIa; fibrinoligase; fibrin stabilizing factor; glutaminylpeptide γ-glutamyltransferase; polyamine transglutaminase; tissue transglutaminase; R-glutaminyl-peptide:amine γ-glutamyl transferase; protein-glutamine γ-glutamyltransferase. Enzyme Commission Number: EC 2.3.2.13. CAS No. 80146-85-6. Transglutaminase. Activity: > 1.5 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing Tr | |
| Native Thermococcus thioreducens Inorganic Pyrophosphatase | Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations. Group: Enzymes. Synonyms: Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. CAS No. 9024-82-2. Purity: ~ 90% (SDS PAGE). Inorganic pyrophosphatase. Mole weight: 20.9 kDa. Storage: at -20°C. Form: Lyophilized powder. Source: Thermococcus thioreducens. Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase. Cat No: NATE-1255. | |
| o-3M3FBS | O-3M3FBS is an activator of phospholipase C (PLC). It stimulates cytoplasmic calcium increase, inositol phosphate formation and superoxide generation in humans. It is used to study PLC signaling in cells and animals in conjunction with the PLC inhibitor U-73122. It is an inactive analog of m-3M3FBS and can be used as a negative control. Synonyms: o-3M3FBS; o 3M3FBS; o3M3FBS; 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]-benzenesulfonamide. Grades: ≥99% by HPLC. CAS No. 313981-55-4. Molecular formula: C16H16F3NO2S. Mole weight: 343.36. | |
| Pentetate sodium calcium | Pentetate sodium calcium. Uses: For analytical and research use. Group: European pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: Calcium sodium diethylenetriaminepentaacetate, Calcium trisodium [[ (carboxymethyl)imino]bis (ethylenenitrilo)]tetraacetate, Trisodium [N-[2-[bis[ (carboxy-κ O)methyl]amino-κ N]ethyl]-N-[2-[[ (carboxy-κ O)methyl] (carboxymethyl)amino-κ N]ethyl]glycinato (5-)-κ N]calciate (3-), [N-[2-[Bis[ (carboxy-κ O)methyl]amino-κ N]ethyl]-N-[2-[[ (carboxy-κ O)methyl] (carboxymethyl)amino-κ N]ethyl]glycinato (5-)-κ N]calciate (3-) sodium (1:3), Trisodium calcium diethylenetriaminepentaacetate, Calcium trisodium pentetate, Calcium-DTPA, Calcium Chel 330, Calcium trisodium DTPA, Glycine, N, N-bis[2-[bis (carboxymethyl)amino]ethyl]-, calcium trisodium salt, Pentacine, Ba 2797, Trisodium [N, N-bis[2-[bis (carboxymethyl)amino]ethyl]glycinato (5-)]calciate (3-), Ditripentat, Penthamil, Calcium trisodium diethylenecin, DTPA calcium trisodium salt, Glycine, N, N-bis[2-[bis (carboxymethyl)amino]ethyl]-, calcium complex, Pentetatec calcium trisodium. CAS No. 12111-24-9. Molecular Formula: C14H18CaN3O10.3Na. Mole Weight: 497.35. Catalog: APS12111249. SMILES: [Na+]. [Na+]. [Na+]. [O-]C (=O)CN12CCN3 (CC (=O)[O-])CC (=O)[O-][Ca+2]1345N (CC2) (CC (=O)[O-]4)CC (=O)[O-]5. Format: Neat. Shipping: Room Temperature. | |
| S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin Sodium Salt | S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt (1:1), Rosuvastatin Calcium Imp. A (EP) as Sodium Salt. CAS No. 1714147-50-8. Pack Sizes: 10MG. IUPAC Name: sodium;(E,3R,5S)-7-[4-(4-fluorophenyl)-2-[(2-hydroxy-2-methylpropyl)sulfonyl-methylamino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate. Molecular Formula: C25H33FN3O7S.Na. Mole Weight: 561.60. Catalog: APS1714147508. SMILES: [Na+]. CC (C)c1nc (nc (c2ccc (F)cc2)c1\C=C\[C@@H] (O)C[C@@H] (O)CC (=O)[O-])N (C)S (=O) (=O)CC (C) (C)O. Format: Neat. Shipping: Room Temperature. | |
| SSR 146977 hydrochloride | SSR 146977 hydrochloride is a potent and selective NK3 receptor antagonist (Ki = 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor, respectively). SSR 146977 also exhibits an inhibitory effect on senktide-induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). Synonyms: SSR 146977 hydrochloride; SSR146977 hydrochloride; SSR-146977 hydrochloride; N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-piperidinyl]-N,N-dimethylurea hydrochloride. Grades: ≥98% by HPLC. CAS No. 264618-38-4. Molecular formula: C35H42Cl2N4O2.HCl. Mole weight: 658.11. | |
| Strontium Ranelate | Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Distrontium renelate; S12911. CAS No. 135459-87-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-17397. | |
| Taurine | Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Aminoethanesulfonic acid. CAS No. 107-35-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0351. | |
| Transglutaminase from guinea pig liver, Recombinant | Transglutaminase from guinea pig liver consists of a single polypeptide chain of 691 amino acid residues. It has six potential glycosylation sites (Asn-X-Ser or Asn-X-Thr), but it is not glycosylated. The molecular mass is approximately 76.6 kDa. It is calcium dependent and has several calcium binding sites. The enzyme is inhibited by iodoacetamide and N-ethylmaleimide in the presence of calcium. It catalyzes the incorporation of small molecular weight amines into γ-glutamine sites of proteins. In the absence of small molecular weight amines, it catalyzes the cross linking of proteins that results in the formation of γ-glutamyl-ε-lysine side chai...tissue transglutaminase; R-glutaminyl-peptide:amine γ-glutamyl transferase; protein-glutamine γ-glutamyltransferase. CAS No. 80146-85-6. Transglutaminase. Activity: > 1.5 units/mg. Storage: at -20°C. Form: Lyophilized powder from 5.0 mM Tris, pH 7.5, 0.5 mM DTE and 1 mM CaCl2. Source: Sf9 cells. Species: Guinea pig liver. transglutaminase; EC 2.3.2.13; 80146-85-6; transglutaminase; Factor XIIIa; fibrinoligase; fibrin stabilizing factor; glutaminylpeptide γ-glutamyltransferase; polyamine transglutaminase; tissue transglutaminase; R-glutaminyl-peptide:amine γ-glutamyl transferase; protein-glutamine γ-glutamyltransferase. Cat No: NATE-1247. | |
| Trisulfide-Calcitonin | Trisulfide-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Trisulfide formation between Cys1 and Cys7). Molecular formula: C145H240N44O48S3. Mole weight: 3463.96. | |
| Urine, Normal | Human Urine formation helps to maintain the balance of minerals and other substances in the body. For example, excess of calcium is normally eliminated through the urine. Urine also excretes ammonia, the build-up of which is harmful to the body. Human urine is the result of a mechanism that maintains the appropriate amount of water in the body. When it leaves the body, Human urine is usually around pH 6, though it may be as low as 4.5 or as high as 8.2. As urea, the compound which accounts for 75-90% of the nitrogen in urine begins to decay, hydroxide ions form, raising the pH as high as 9-9.3. The decay of urea into carbon dioxide is catalyzed by urease. Group: Biologicals. Pack Sizes: 1L. US Biological Life Sciences. | Worldwide |
| VEL-0230 | VEL-0230, also known as NC-2300, is a potent cathespin K inhibitor. VEL-0230 has dual-acting properties that both stimulates bone formation and inhibits loss. VEL-0230 is being studied preclinically for the treatment of diseases involving bone mineral disorders such as bone loss related to multiple myeloma, osteoporosis, bone metastases, and rheumatoid arthritis. Velcura Therapeutics is currently being developed by Velcura Therapeutics. Given VEL- 0230's promotion of bone formation, inhibition of bone loss and reduction of calcium levels, Velcura has chosen Myeloma as its lead indication, as the bone fragility, bone pain, high calcium levels and eventual kidney involvement present serious medical and quality of life issues to affected patients. Synonyms: VEL 0230; VEL0230; NC-2300; NC2300; NC 2300; sodium (2S,3S)-3-(((S)-1-isobutoxy-4-methylpentan-2-yl)carbamoyl)oxirane-2-carboxylate. CAS No. 221144-20-3. Molecular formula: C14H24NNaO5. Mole weight: 309.33. | |
| Zofenopril calcium | Zofenopril Calcium (SQ26991) is an orally active angiotensin-converting enzyme ( ACE ) inhibitor with antioxidant activity and cardioprotective effects. Zofenopril Calcium reduces ROS production and GSH consumption and helps inhibit foam cell formation, thus slowing the progression of atherosclerosis. Zofenopril Calcium prevents cardiac damage caused by chronic Doxorubicin (HY-15142A). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ26991. CAS No. 81938-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0655. | |
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