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[2- [ [ [ (Phenylmethyl) amino] carbonyl] amino] ethyl] -carbamic Acid 1,1-dimethylethyl Ester is an intermediate in the synthesis of N-(Diaminoethylene)-N'-( β-D-ribofuranosyl)-carbamimidicAcid (D416225). It is used in the preperation of unsymmetrical ureas. Group: Biochemicals. Grades: Highly Purified. CAS No. 874394-05-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23N3O3. US Biological Life Sciences.
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BX-517
BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidicacid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3.
O-Ethyl-N,N'-diisopropylisourea
O-Ethyl-N,N'-diisopropylisourea. Group: Biochemicals. Alternative Names: N, N'-Diisopropyl carbamimidicAcid Ethyl Ester; Ethyl N, N'-Diisopropyl carbamimidate. Grades: Highly Purified. CAS No. 60683-30-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
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O-Methyliso Urea Tosylate Salt
An intermediate in the production of Guanidinoacetic Acid. Group: Biochemicals. Alternative Names: O-Methylisourea p-Toluenesulfonate; CarbamimidicAcid Methyl Ester, 4-Methyl Benzene sulfonate; NSC 64951. Grades: Highly Purified. CAS No. 7356-58-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
O,N,N'-Triisopropylisourea
O,N,N'-Triisopropylisourea. Group: Biochemicals. Alternative Names: N, N'-Diisopropyl carbamimidicAcid Isopropyl Ester; Isopropyl N, N'-Diisopropyl carbamimidate. Grades: Highly Purified. CAS No. 63460-32-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
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Urea
Pharmacopeia & Metrological Institutes Standards; Pharma & Vet Compounds & Metabolites; Pharma & Vet Compounds & Metabolites; British Pharmacopoeia; European Pharmacopoeia (Ph. Eur.); Impurity Standards; Pharmacopoeial Standards. Uses: For analytical and research use. Group: Reagents. Alternative Names: Carbamide, Cellpaste K 4, Pastaron 20, Urepeal,Urea, Onyster, Ultra Low Biuret Urea, Carmol 40, Isourea, Pastaron soft, AdBlue, DEF (diesel exhaust fluid), ESN, Nutraplus, Aquacare, Elaqua XX, Urepearl, Varioform II, Carbonyl diamide, Basodexan, Uroderm, Rubinol ST 010, UR, Optigen II, Carbamimidicacid, B-I-K, Onychomal, Ureophil, Hyanit, Duration III, Pastaron, AUS 32, Ureaphil, Keratinamin Kowa, NSC 34375, Pastaron 20 soft, Benural 70, Pastaron 10, Urea perhydrate, Urepeal L, Urevert, Keratinamin, Eucerin 10% Urea Lotion, Optigen 1200, SGN 250, Low Biuret Urea, Cellton NP, Pseudourea, Aquadrate, Uria, DEF, Diesel exhaust fluid. CAS No. 57-13-6. Pack Sizes: 200MG. IUPAC Name: urea.
Urea-13C
Labeled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic. Group: Biochemicals. Alternative Names: Aquacare-13C; Aquadrate-13C; B-I-K-13C; Basodexan-13C; Benural 70-13C; Carbamide-13C; CarbamimidicAcid-13C; Carbonyl Diamide-13C; Carmol 40-13C. Grades: Highly Purified. CAS No. 58069-82-2. Pack Sizes: 10mg. US Biological Life Sciences.
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Urea-13C,15N2
Labeled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic. Group: Biochemicals. Alternative Names: Aquacare-13C,15N2; Aquadrate-13C,15N2; B-I-K-13C,15N2; Basodexan-13C,15N2; Benural 70-13C,15N2; Carbamide-13C,15N2; CarbamimidicAcid-13C,15N2; Carbonyl Diamide-13C,15N2; Carmol 40-13C,15N2;l-13C,15N2. Grades: Highly Purified. CAS No. 78405-35-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Urea-15N2
Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic. Group: Biochemicals. Alternative Names: Aquacare-15N2; Aquadrate-15N2; B-I-K-15N2; Basodexan-15N2; Benural 70-15N2; Carbamide-15N2; CarbamimidicAcid-15N2; Carbonyl Diamide-15N2; Carmol 40-15N2. Grades: Highly Purified. CAS No. 2067-80-3. Pack Sizes: 10mg, 250mg, 1g. US Biological Life Sciences.
(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride. Group: Biochemicals. Alternative Names: (10-methyl-9-anthracenyl)methyl Ester Carbamimidothioic Acid Monohydrochloride; NSC 146109. Grades: Highly Purified. CAS No. 59474-01-0. Pack Sizes: 10mg. Molecular Formula: C17H17ClN2S, Molecular Weight: 316.85. US Biological Life Sciences.
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1-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide Penta-acetate D-Gluconic Acid Salt
1-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide penta-acetate D-gluconic acid salt is one of chlorhexidine intermediates. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: (1S) -1, 2, 3, 4, 5-Penta-O-acetyl-1-C-{4-[ (4-chlorophenyl) amino]-6-[ (6-{N'-[N- (4-chlorophenyl) carbamimidoyl]carbamimidamido}hexyl) amino]-1, 3, 5-triazin-2-yl}-D-arabinitol 2,3,4,5,6-penta-O-acetyl-D-gluconic acid (1:1). Molecular formula: C38H48Cl2N10O10.C16H22O12. Mole weight: 1282.09.
2-(2-Aminoethyl)isothiourea dihydrobromide is a pan-inhibitor of all NOS isoforms with Kis of 1.8, 2.1, and 0.59 μM for human nNOS, eNOS, and iNOS, respectively. Uses: Radiation-protective agents. Synonyms: Carbamimidothioic acid, 2-aminoethyl ester, hydrobromide (1:2); Carbamimidothioic acid, 2-aminoethyl ester, dihydrobromide; Pseudourea, 2-(2-aminoethyl)-2-thio-, dihydrobromide; 2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide; 2-(2-Aminoethyl)-2-thiopseudourea hydrobromide; 2-(β-Aminoethyl)isothiuronium bromide hydrobromide; AET; Antiradon; Ixecur; NSC 22877; S-(2-Aminoethyl)isothiuronium bromide hydrobromide; S-(β-Aminoethyl)isothiuronium bromide hydrobromide; Surrectan; S-(2-aminoethyl) Isothiourea dihydrobromide. Grades: 95%. CAS No. 56-10-0. Molecular formula: C3H11Br2N3S. Mole weight: 281.01.
2-(2-Sulfoethyl)pseudourea
2-(2-Sulfoethyl)pseudourea is an impurity of Mesna. It is an amidinosulfonate used in dyes, topical compositions in cosmetics as well as in formulations of gray hair-preventing agents. Synonyms: 2-[ (Aminoiminomethyl) thio]ethanesulfonic Acid; 2-S-Thiuronium Ethanesulfonate; 2-(Amidinothio)ethanesulfonic Acid; 2-S-Thiuronium Ethanesulfonate; Carbamimidothioic Acid 2-Sulfoethyl Ester; Mesna Impurity. Grades: > 95%. CAS No. 25985-57-3. Molecular formula: C3H8N2O3S2. Mole weight: 184.24.
2-(2-Sulfoethyl)pseudourea
An impurity of Mesna. An amidinosulfonate used in dyes, topical compositions in cosmetics as well as in formulations of gray hair-preventing agents. Group: Biochemicals. Alternative Names: 2-[ (Aminoiminomethyl) thio]ethanesulfonic Acid; 2-S-Thiuronium Ethanesulfonate; 2- (Amidinothio) ethanesulfonic Acid; 2-S-Thiuronium Ethanesulfonate; Carbamimidothioic Acid 2-Sulfoethyl Ester. Grades: Highly Purified. CAS No. 25985-57-3. Pack Sizes: 1g. US Biological Life Sciences.
2-[4-[ (4-Nitrophenyl) methoxy]phenyl]ethyl Ester Carbamimidothioic Acid is an inhibitor of the reversed sodium-calcium exchanger (NCX). NCX is a potential therapeutic target for treatment in heart failure and myocardial ischemia-reperfusion. Group: Biochemicals. Grades: Highly Purified. CAS No. 182004-64-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H17N3O3S, Molecular Weight: 331.39. US Biological Life Sciences.
(2-Bromo-6-fluorophenyl) carbamimidothioic Acid Methyl Ester Monohydriodide is an intermediate in the synthesis of Romifidine (R640050), an α2 agonist used as a sedative and analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 65896-13-1. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H9BrFIN2S. US Biological Life Sciences.
(5-Chloro-2,1,3-benzothiadiazol-4-yl)-carbamimidothioic Acid Methyl Ester Hydriodide Salt
Tizanidine intermediate. Group: Biochemicals. Alternative Names: (5-Chloro-2,1,3-benzothiadiazol-4-yl)-carbamimidothioic Acid Methyl Ester Monohydriodide. Grades: Highly Purified. CAS No. 51323-03-6. Pack Sizes: 50mg. US Biological Life Sciences.
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a-(4-Chlorophenyl)thio urea
a-(4-Chlorophenyl)thio urea. Group: Biochemicals. Alternative Names: 1-(p-Chlorophenyl)-2-thio-urea; N'- (4-Chlorophenyl) carbamimidothioic acid; NSC 72217. Grades: Highly Purified. CAS No. 3696-23-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C7H7ClN2S. US Biological Life Sciences.
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Antioxidant peptide A
Antioxidant peptide A is a short peptide that contains alternative aromatic or sulfur-containing amino acids. The side chain of antioxidant peptide A is thought to contribute to the strong free radical scavenging activity of the peptide in tumor cells. Synonyms: H-Pro-His-Cys-Lys-Arg-Met-OH; L-prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl-L-methionine; N-[(2S,5S,8R,11S)-5-(4-Aminobutyl)-2-(3-carbamimidamidopropyl)-1,4,7,10,13-pentahydroxy-11-(1H-imidazol-5-ylmethyl)-13-[(2S)-2-pyrrolidinyl]-8-(sulfanylmethyl)-3,6,9,12-tetraazatrideca-3,6,9,12-tetraen-1-ylidene]methionine. Grades: >95%. CAS No. 159147-88-3. Molecular formula: C31H54N12O7S2. Mole weight: 770.97.
Arginine
Arginine. Uses: For analytical and research use. Group: Api standards; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: L-(+)-Arginine, N5-(Aminoiminomethyl)-L-ornithine, L-alpha-Amino-delta-guanidinovaleric acid, NSC 206269,(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid, 5-[(Aminoiminomethyl)amino]-L-norvaline, L-Arg, Arginine. CAS No. 74-79-3. IUPAC Name: (2S)-2-amino-5-carbamimidamidopentanoic acid. Molecular Formula: C6H14N4O2. Mole Weight: 174.20. Catalog: APS74793. SMILES: N[C@@H](CCCNC(=N)N)C(=O)O. Format: Neat.
Arginomycin
Arginomycin is a nucleoside antibiotic produced by Streptomyces arginensis. It has weak activity against Gram-positive bacteria and fungi. Synonyms: beta-D-erythro-Hex-2-enopyranuronic acid, 4-((2-amino-5-((aminoiminomethyl)methylamino)-3-methyl-1-oxopentyl)amino)-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-; 3-[[2-amino-5-[carbamimidoyl(methyl)amino]-3-methylpentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid. CAS No. 106133-33-9. Molecular formula: C18H28N8O5. Mole weight: 436.46.
Avoralstat
Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid; BCX-4161; BCX 4161; BCX4161; Avoralstat. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54.
Azilsartan Impurity K
Azilsartan Impurity K. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-((2'-carbamimidoyl-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid. CAS No. 1442400-65-8. Molecular Formula: C24H22N4O3. Mole Weight: 414.46. Catalog: APB1442400658.
Azilsartan Impurity L
Azilsartan Impurity L acts as a new angipotensin II receptor antagonist in mammals. Synonyms: 3-((2-carbamimidoylbiphenyl-4-yl)methyl)-2-ethoxy-3H-benzo[d]imidazole-4-carboxylic acid; 1-[[2'-(Aminoiminomethyl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid. Grades: > 95%. CAS No. 1442400-65-8. Molecular formula: C24H22N4O3. Mole weight: 414.47.
BC 11 hydrobromide
BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 μM) with no activity at 8 other related enzymes. BC 11 inhibits clot lysis displaying no effect on clot formation. It also decreases viability of MDA-MB231 breast cancer cells in vitro. Synonyms: BC11 hydrobromide; BC-11 hydrobromide; BC 11 hydrobromide; BC-11 HBr Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide; [4- (carbamimidoylsulfanylmethyl) phenyl]boronic acid hydrobromide. CAS No. 443776-49-6. Molecular formula: C8H11BN2O2S.HBr. Mole weight: 290.97.
BCX 1470 methanesulfonate
BCX 1470 methanesulfonate is methanesulfonate salt form of BCX 1470. In vitro BCX 1470 inhibits the esterolytic and hemolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM) which is the complement enzymes. BCX 1470 may used for the treatment of c. Synonyms: BCX 1470 methanesulfonate; BCX-1470 methanesulfonate; BCX1470 methanesulfonate; (2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate;methanesulfonic acidBCX 1470 (methanesulfonate)217099-44-0BCX 1470 (methanesulfonate) CHEMBL2203422C14H10N2O2S2. CH4O3S3166AH2- (Aminoiminomethyl) benzo[b]thiophen-6-yl ester 2-thiophenecarb. Grades: 95%. CAS No. 217099-44-0. Molecular formula: C14H10N2O2S2.CH4O3S. Mole weight: 398.47.
BMS-36313
BMS-363131 is very potent inhibitor of human tryptase with inhibitory activity against bovine trypsin. Uses: Tryptase inhibitor. Synonyms: BMS-363131; BMS 363131; BMS363131. (2S,3R)-3-[[(3R)-1-carbamimidoylpiperidin-3-yl]methyl]-4-oxo-1-[4-(6-phenylhexanoyl)piperazine-1-carbonyl]azetidine-2-carboxylic acid. Grades: ≥98%. CAS No. 384829-65-6. Molecular formula: C28H40N6O5. Mole weight: 540.66.
BMS-593214
BMS-593214 is an active-site, direct FVIIa inhibitor. It displayed direct, competitive inhibition of human FVIIa in the hydrolysis of a tripeptide substrate with Ki of 5 nM. Synonyms: BMS593214; BMS 593214; 2'-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5'-hydroxy-4'-methoxy-biphenyl-4-carboxylic acid. Grades: >98%. CAS No. 1004551-40-9. Molecular formula: C31H27N3O4. Mole weight: 505.56.
Carbamimidothioic Acid 9-Hydroxynonyl Ester Bromide is an intermediate in the preparation of Fulvestrant, which is a selective estrogen receptor degrader (SERD) used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Synonyms: Carbamimidothioic Acid 9-Hydroxynonyl Ester Monobromide; Amino[(9-hydroxynonyl)sulfanyl]methaniminium bromide. Grades: ≥95%. CAS No. 511545-93-0. Molecular formula: C10H23BrN2OS. Mole weight: 299.27.
Used in the preparation of Fulvestrant intermediates. Group: Biochemicals. Alternative Names: Carbamimidothioic Acid 9-Hydroxynonyl Ester Monobromide. Grades: Highly Purified. CAS No. 511545-93-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Carbamimidothioic acid methyl ester
Carbamimidothioic acid methyl ester. Group: Biochemicals. Alternative Names: 2-Methyl-2-thiopseudourea. Grades: Highly Purified. CAS No. 2986-19-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C2H8N2O4S2. US Biological Life Sciences.
Clobenpropit dihydrobromide is a highly potent histamine H3 antagonist/inverse agonist (pA2=9.93) that can cross blood-brain barrier. It also displays partial agonist activity at H4 receptors. Synonyms: Carbamimidothioic acid, N-[(4-chlorophenyl)methyl]-, 3-(1H-imidazol-5-yl)propyl ester, hydrobromide (1:2); Carbamimidothioic acid, [(4-chlorophenyl)methyl]-, 3-(1H-imidazol-4-yl)propyl ester, dihydrobromide; Clobenpropit hydrobromide; 3-(1H-imidazol-5-yl)propyl (4-chlorobenzyl)carbamimidothioate dihydrobromide. Grades: ≥99% by HPLC. CAS No. 145231-35-2. Molecular formula: C14H17ClN4S.2HBr. Mole weight: 470.65.
Creatine
Nutritional Composition Compounds; API Standards. Uses: For analytical and research use. Group: Reagents. Alternative Names: Creatine. CAS No. 57-00-1. IUPAC Name: 2-[carbamimidoyl(methyl)amino]acetic acid.
Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Creatine HCl; 2-(1-Methylguanidino)acetic acid hydrochloride; 2-[carbamimidoyl(methyl)amino]acetic acid hydrochloride. Grades: 95%. CAS No. 17050-09-8. Molecular formula: C4H10ClN3O2. Mole weight: 167.593.
Creatine monohydrate
Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer.Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-[carbamimidoyl(methyl)amino]acetic acid;hydrate. CAS No. 6020-87-7. Molecular formula: C4H11N3O3. Mole weight: 149.15.
Dabigatran Impurity 37
Dabigatran Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2- ( ( (4- (N- ( (hexyloxy) carbonyl) carbamimidoyl) phenyl) amino) methyl) -1-methyl-1H-benzo[d]imidazole-5-carboxylic acid. Molecular Formula: C24H29N5O4. Mole Weight: 451.52. Catalog: APB04985.
Dabigatran impurity A
Dabigatran impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid. CAS No. 211914-51-1. Molecular Formula: C25H25N7O3. Mole Weight: 471.51. Catalog: APB211914511.
Dabigatran impurity B
Dabigatran impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3- (2- ( ( (4- (N- ( (hexyloxy) carbonyl) carbamimidoyl) phenyl) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoic acid. CAS No. 212321-78-3. Molecular Formula: C32H37N7O5. Mole Weight: 599.68. Catalog: APB212321783.
Arginine is an alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. It has a role as a fundamental metabolite. It is an alpha-amino acid, a member of guanidines and a polar amino acid. It contains a 3-carbamimidamidopropyl group. It is a conjugate base of an argininium(1+). It is a conjugate acid of an argininate. Synonyms: H-DL-Arg-OH; (±)-Arginine; 2-Amino-5-(carbamimidamido)pentanoic Acid; 2-Amino-5-guanidinopentanoic Acid; D(-)-Arginine; arginin; (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid; H DL Arg OH. Grades: 97.0%-102.0% (Assay). CAS No. 7200-25-1. Molecular formula: C6H14N4O2. Mole weight: 174.20.
An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, showing that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: 2-[[[4- (Aminoiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride; Dabigatran impurity 14. Grades: ≥95%. CAS No. 1422435-39-9. Molecular formula: C19H22ClN5O2. Mole weight: 387.86.
FR295389 free base
FR295389 free base is a new cephalosporin. It shows effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 free base has effective antibacterial activity. Synonyms: FR-295389 free base; FR 295389 free base; FR295389 free base; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: >98 %. CAS No. 1019207-71-6. Molecular formula: C25H33N13O7S2. Mole weight: 691.74.
FR295389 sulfuric acid
FR295389 sulfuric acid is the sulfate form of FR295389, which is a new cephalosporin. It has effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 sulfuric acid has effective antibacterial activity. Synonyms: FR-295389 sulfuric acid; FR 295389 sulfuric acid; FR295389 sulfuric acid; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfuric acid. Grades: >98 %. CAS No. 1019207-72-7. Molecular formula: C25H35N13O11S3. Mole weight: 789.81.
Gabexate
Gabexate mesylate is a serine protease inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation, and as a regional anticoagulant for haemodialysis. Uses: Serine protease inhibitor. Synonyms: GABEXATE; GabexateMesylateBase; [N'-[5- (4-ethoxycarbonylphenoxy) carbonylpentyl]carbamimidoyl]azanium methanesulfonate;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester. Grades: ≥98%. CAS No. 39492-01-8. Molecular formula: C16H23N3O4. Mole weight: 321.375.
H-D-Phe-Phe-Arg-chloromethylketone
H-D-Phe-Phe-Arg-chloromethyl ketone is a potent, specific and irreversible inhibitor of glandular and plasma kallikreins. Uses: Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Synonyms: FFRCK; Phenylalanyl-phenylalanyl-arginine chloromethyl ketone; Phe-phe-arg-CK; 2-Amino-N-[N-(6-carbamimidamido-1-chloro-2-oxohexan-3-yl)phenylalanyl]-3-phenylpropanimidic acid; PPACK II. CAS No. 74392-49-7. Molecular formula: C25H33ClN6O3. Mole weight: 501.02.
H-Gly-Arg-Gly-Asp-Ser-NH2
H-Gly-Arg-Gly-Asp-Ser-NH2 can be coupled to the carrier via its free N-terminal. Synonyms: GRGDS-amide; H-GRGDS-NH2; (3S)-3-{[2-({(2S)-2-[(2-Amino-1-hydroxyethylidene)amino]-5-carbamimidamido-1-hydroxypentylidene}amino)-1-hydroxyethylidene]amino}-4-{[(2S)-1,3-dihydroxy-1-imino-2-propanyl]imino}-4-hydroxybutanoic acid; glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-serinamide. Grades: ≥95%. CAS No. 143648-02-6. Molecular formula: C17H31N9O8. Mole weight: 489.48.
Iodophenpropit dihydrobromide
Iodophenpropit dihydrobromide is a selective and high affinity histamine H3 antagonist (KD = 0.3 nM). Synonyms: Carbamimidothioic acid, [2-(4-iodophenyl)ethyl]-, 3-(1H-imidazol-4-yl)propyl ester, dihydrobromide; N-[2-(4-Iodophenyl)ethyl]-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide; 3-(1H-imidazol-5-yl)propyl (4-iodophenethyl)carbamimidothioate dihydrobromide. Grades: ≥98% by HPLC. CAS No. 145196-87-8. Molecular formula: C15H19IN4S.2HBr. Mole weight: 576.13.
Kevetrin
Kevetrin (thioureidobutyronitrile), is a water-soluble, small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity. Upon intravenous administration, thioureidobutyronitrile activates p53 which in turn induces the expressions of p21 and PUMA (p53 up-regulated modulator of apoptosis), thereby inhibiting cancer cell growth and causing tumor cell apoptosis. Thioureidobutyronitrile may be effective in drug-resistant cancers with mutated p53. p53 tumor suppressor, a transcription factor regulating the expression of many stress response genes and mediating various anti-proliferative processes, is often mutated in cancer cells. Synonyms: 4-Isothioureidobutyronitrile; NSC-525990; Carbamimidothioic acid, 3-cyanopropyl ester; thioureido butyronitrile. CAS No. 500863-50-3. Molecular formula: C5H9N3S. Mole weight: 143.21.
Kevetrin hydrochloride
Kevetrin hydrochloride is a water-soluble small molecule with potential antineoplastic activity. Uses: Inhibiting cancer cell growth and causing tumor cell apoptosis. Synonyms: UNII-NL6L2371DP; thioureidobutyronitrile; 3-cyanopropyl carbamimidothioate;hydrochloride; Carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride. Grades: ≥95%. CAS No. 66592-89-0. Molecular formula: C5H10ClN3S. Mole weight: 179.66.
L-homoarginine
L-homoarginine is a non-essential and non-proteinogenic amino acid, and acts as a competitive substrate for nitric oxide synthase (NOS), whereas asymmetric dimethylarginine (ADMA) is a NOS inhibitor. It is also a human arginase inhibitor. Synonyms: L-Lysine, N6-(aminoiminomethyl)-; Lysine, N6-amidino-; Lysine, N6-amidino-, L-; N6-(Aminoiminomethyl)-L-lysine; Homo-L-arginine; Homoarginine; NSC 27429; NSC 88868; N6-carbamimidoyl-L-lysine. Grades: ≥95%. CAS No. 156-86-5. Molecular formula: C7H16N4O2. Mole weight: 188.23.
LL-BM-726
LL-BM-726 is a water-soluble antibiotic produced by the strain of Streptomyces BM726. And it has anti-gram-negative bacteria activity. Synonyms: LL-BM726; [(2-Amino-5-carbamimidamido-1-hydroxypentylidene)amino](1-hydroxy-2-oxocyclopent-3-en-1-yl)acetic acid. Grades: >98%. CAS No. 96695-56-6. Molecular formula: C13H21N5O5. Mole weight: 327.34.
It is produced by the strain of Microcystis aeruginosa. Synonyms: 3-L-Tryptophan-5-L-arginine cyanoginosin La; (5R,8S,11R,12S,15S,18S,19S,22R)-15-(3-Carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16 ,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid. Grades: ≥98%. CAS No. 138234-58-9. Molecular formula: C54H73N11O12. Mole weight: 1068.24.
N1,N2-Diboc N-[6-[(Aminoiminomethyl)amino]hexyl]-N'-(4-chlorophenyl)-imidodicarbonimidic Diamide is an intermediate for the synthesis of Chlorhexidine, which is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: Bis(2-methyl-2-propanyl) { (Z) -[ (6-{N'-[N- (4-chlorophenyl) carbamimidoyl]carbamimidamido}hexyl) amino]methylylidene}biscarbamate; Carbamic acid, N, N'- [ (Z) - [ [6- [ [ [ [ [ (4-chlorophenyl) amino] iminomethyl] amino] iminomethyl] amino] hexyl] amino] methylidyne] bis-, bis(1,1-dimethylethyl) ester. Molecular formula: C25H41ClN8O4. Mole weight: 553.10.
Nafamostat is a broad spectrum serine protease inhibitor and kallikrein inhibitor. It inhibits blood coagulation and used as an anticoagulant. It is also a possible complement inhibitor. It is mainly used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. It is formulated with HCl salt due to its basic tendencies. Uses: Nafamostat inhibits blood coagulation and used as an anticoagulant. it is also a possible complement inhibitor. it is mainly used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Synonyms: FUT-175; FUT 175; FUT175; 6-Amidino-2-naphthyl 4-guanidinobenzoate;(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate; Benzoic acid,4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester. Grades: 95%. CAS No. 81525-10-2. Molecular formula: C19H17N5O2. Mole weight: 347.37.
Fmoc-Arg(Me,pbf)-OH can be used as a reactant/reagent in design, synthesis and structure-activity relationship of macrocyclic peptidomimetics that bind to WDR5 and block WDR5-MLL protein-protein interaction. Synonyms: Fmoc-L-Arg(Me,Pbf)-OH; N5-[[[ (2, 3-Dihydro-2, 2, 4, 6, 7-pentamethyl-5-benzofuranyl)sulfonyl]amino] (methylimino)methyl]-N2-[ (9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine; Fmoc-Arg(Me, Pbf)-OH; (2S) -2- (9H-fluoren-9-ylmethoxycarbonylamino) -5- [ [N \ '-methyl-N- [ (2, 2, 4, 6, 7-pentamethyl-3H-1-benzofuran-5-yl) sulfonyl] carbamimidoyl] amino] pentanoic acid; (S,E)-12-(9H-fluoren-9-yl)-10-oxo-3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonylimino)-11-oxa-2,4,9-triazadodecane-8-carboxylic acid; (S, E) -2- ( ( ( (9H-fluoren-9-yl) methoxy) carbonyl) amino) -5- ( ( (methylamino) (2, 2, 4, 6, 7-pentamethyl-2, 3-dihydrobenzofuran-5-sulfonamido) methylene) amino) pentanoic acid; N-alpha-(9-Fluorenylmethoxycarbonyl)-N-omega1-methyl-N-omega2-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine. Grades: ≥ 99.2% (Chiral HPLC). CAS No. 1135616-49-7. Molecular formula: C35H42N4O7S. Mole weight: 662.80.
N, N'-Dicyclohexyl carbamimidothioic Acid (5,6-Dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl Ester Hydrochloride
N, N'-Dicyclohexyl carbamimidothioic Acid (5,6-Dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl Ester Hydrochloride. Group: Biochemicals. Alternative Names: IT1t. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C21H36Cl2N4S2, Molecular Weight: 479.57. US Biological Life Sciences.
Worldwide
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4-carbamimidoylphenyl) (nitroso)amino)methyl)-1-methyl-N- (pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate, 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C29H29N8O6F3. Mole weight: 642.59.
NSC 146109 hydrochloride
NSC 146109 hydrochloride is a genotype-selective antitumor agent. It can activate p53-dependent transcription. Synonyms: NSC 146109 hydrochloride; NSC146109 hydrochloride; NSC-146109 hydrochloride; (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride. Grades: ≥99% by HPLC. CAS No. 59474-01-0. Molecular formula: C17H16N2S.HCl. Mole weight: 316.85.
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