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| Product | Description | |
|---|---|---|
| Chloroquine | An antimalarial agent. Synonyms: Aralen; Chlorochin; Chloraquine. Grades: 99.98%. CAS No. 54-05-7. Molecular formula: C18H26ClN3. Mole weight: 319.87. |  |
| Chloroquine | Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 50 =1.13 μM) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-05-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17589A. |  |
| Chloroquine | Chloroquine used in the treatment of malaria and MDR-strains. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine; (±) -Chloroquine; 7-Chloro-4- [ [4- (diethylamino) -1-methylbutyl] amino] quinoline; Aralen; Artrichin; Bipiquin; Capquin; Chloraquine; Chlorochin; Chlorolex; loquin; E-Vivax; Hcqs; Maliago; NSC 187208; Nivaquinp; Premoquine; RP 3377; Reumachlor; Ronaquine;Rosq; ST 121; ST 121 (Pharmaceutical); Sequin. Grades: Highly Purified. CAS No. 54-05-7. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??ClN?, Molecular Weight: 319.87. US Biological Life Sciences. |  Worldwide |
| Chloroquine | Chloroquine. Uses: For analytical and research use. Group: Covid-19 research and reference materials; pharmaceutical toxicology. Alternative Names: 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline, Chlorolex, Premoquine, ST 121 (Pharmaceutical), loquin, Hcqs, RP 3377,N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, ST 121, (±)-Chloroquine, Maliago, Chlorochin, Ronaquine, Sequin, Capquin, NSC 187208, Nivaquinp, Aralen, Artrichin, Chloraquine, Reumachlor, E-Vivax, Rosq, Bipiquin. CAS No. 54-05-7. IUPAC Name: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine. Molecular Formula: C18H26ClN3. Mole Weight: 319.87. Catalog: APS54057. SMILES: CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12. Format: Neat. |  |
| CHLOROQUINE | CHLOROQUINE Inhibitor. Uses: Scientific use. Product Category: T8689. CAS No. 54-05-7. |  |
| Chloroquine-d4 Diphosphate Salt | Labeled anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine-d4 Diphosphate Salt; Aralen-d4 diphosphate; Aralen-d4 Phosphate; Arechin-d4; Avloclor-d4; Bemaphate-d4; Chingamin-d4; Chingamin-d4 Phosphate; SN 7618-d4; Sanoquin-d4;Tanakan-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Chloroquine dihydrochloride | Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 50 =1.13 μM) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3545-67-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17589B. | |
| Chloroquine Dihydrochloride | Chloroquine diphosphateis an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM). Synonyms: 1,?4-Pentanediamine, N4-(7-chloro-4-quinolinyl)?-N1,?N1-diethyl-, hydrochloride. Grades: > 95%. CAS No. 3545-67-3. Molecular formula: C18H28Cl3N3. Mole weight: 392.79. | |
| Chloroquine diphosphate | 100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: C18H32ClN3O8P2. CAS No. 50-63-5. Prepack ID 17838227-100g. Molecular Weight 515.86. See USA prepack pricing. |  |
| Chloroquine Diphosphate Salt | Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate Salt; Aralen Diphosphate; Aralen Phosphate; Arechin; Avloclor; Bemaphate; Chingamin; Chingamin Phosphate; SN 7618; Sanoquin; Tanakan. Grades: Highly Purified. CAS No. 50-63-5. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C??H??ClN?O?P?, Molecular Weight: 515.86. US Biological Life Sciences. | Worldwide |
| Chloroquine diphosphate salt 99+% | Chloroquine diphosphate salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Chloroquine phosphate | Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 50 =1.13 μM) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-63-5. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-17589. | |
| Chloroquine phosphate | Chloroquine phosphate is an antimalarial drug and weak intercalating agent. It inhibits TLR signalling in plasmacytoid dendritic cells (pDCs). It has been used in emergency of COVID-19. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt; Aralen diphosphate; C2301; C 2301; C-2301; Chloroquine Diphosphate. Grades: ≥98% (HPLC). CAS No. 50-63-5. Molecular formula: C18H32ClN3O8P2. Mole weight: 515.86. | |
| Chloroquine Phosphate BP | Chloroquine Phosphate BP. |  CA, FL & NJ |
| Desethyl chloroquine | Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity. Group: Inhibitors. Alternative Names: DESETHYL CHLOROQUINE; Deethylchloroquine; Monodeethylchloroquine; N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1, 4-pentanediamine; NSC 13254;WR 29623;4-[[1-Methyl-4-(ethylamino)butyl]amino]-7-chloroquinoline;N'-(7-Chloroquinolin-4-yl)-N-ethyl-1,4-pentanediamine. CAS No. 1476-52-4. Molecular formula: C16H22ClN3. Mole weight: 291.82. Appearance: Tan Solid. Catalog: ACM1476524. |  |
| Desethyl Chloroquine | The major product of the stereoselective human metabolism of Chloroquine, a medication used for the therapy and prevention of malaria. Synonyms: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine; Deethylchloroquine; Monodeethylchloroquine. Grades: > 95%. CAS No. 1476-52-4. Molecular formula: C16H22ClN3. Mole weight: 291.82. | |
| Desethyl Chloroquine | The major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine; Deethylchloroquine; Monodeethyl chloroquine; NSC 13254; WR 29623. Grades: Highly Purified. CAS No. 1476-52-4. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Desethyl chloroquine-d4 | 2H Labeled Compounds. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine-d4; Deethylchloroquine-d4; Monodeethylchloroquine-d4; NSC 13254-d4; WR 29623-d4. CAS No. 1189971-72-9. Molecular formula: C16H18D4ClN3. Mole weight: 295.84. Catalog: ACM1189971729. | |
| Desethyl Hydroxy Chloroquine HCl | Grades: > 95%. Molecular formula: C16H23Cl2N3O. Mole weight: 344.29. | |
| Didesethyl Chloroquine | A metabolite of Chloroquine. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-1,4-pentanediamine; 4-[(4-Amino-1-methylbutyl)amino]-7-chloroquinoline; Bisdeethylchloroquine; Bisdesethyl chloroquine; N,N-Dideethylchloroquine. Grades: Highly Purified. CAS No. 4298-14-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Didesethyl Chloroquine | A metabolite of Chloroquine. Synonyms: N4-(7-Chloro-4-quinolinyl)-1,4-pentanediamine; 4-[(4-Amino-1-methylbutyl)amino]-7-chloroquinoline; Bisdeethylchloroquine; Bisdesethylchloroquine; N,N-Dideethylchloroquine. Grades: > 95%. CAS No. 4298-14-0. Molecular formula: C14H18ClN3. Mole weight: 263.77. | |
| Didesethyl Chloroquine-d4 | A labeled metabolite of Chloroquine. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-1,4-pentanediamine-d4; 4-[(4-Amino-1-methylbutyl)amino]-7-chloroquinoline-d4; Bisdeethylchloroquine-d4; Bisdesethylchloroquine-d4; N,N-Dideethylchloroquine-d4. Grades: Highly Purified. CAS No. 1215797-41-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Didesethyl Chloroquine Hydroxyacetamide | An intermediate in the preparation of Cletoquine Oxalate. Group: Biochemicals. Alternative Names: 4-(4-Glycolamidyl-1-methyl-3,4-butylamino)-7-chloroquinoline. Grades: Highly Purified. CAS No. 1159977-30-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Didesethyl Chloroquine Hydroxyacetamide-d4 | An intermediate in the preparation of labeled Cletoquine Oxalate. Group: Biochemicals. Alternative Names: 4-(4-Glycolamidyl-1-methyl-3,4-d4-butylamino)-7-chloroquinoline. Grades: Highly Purified. CAS No. 1216956-86-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Hydroxychloroquine | An antimalarial; antirheumatic; lupus erythematosus suppressant. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.2 Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus.12 Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. It was developed during World War II as a derivative of quinacrine with less severe side effects. Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. Hydroxychloroquine was granted FDA approval on 18 April 1955. Hydroxychloroquine is indicated for the prophylaxis of malaria where chloroquine resistance is not reported, treatment of uncomplicated malaria (caused by P. falciparum, P. malariae, P. ovale, or P. vivax), chronic discoid lupus erythematosus, system Group: Biochemicals. Alternative Names: 2-[{4-[ (7-Chloroquinolin-4-yl)amino]pentyl} (ethyl)amino]ethanol; 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline; Plaquenil; Oxichloroquine; Oxychloro. Grades: Highly Purified. CAS No. 118-42-3. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C??H??ClN?O, Molecular Weight: 335.87. US Biological Life Sciences. | Worldwide |
| Hydroxychloroquine N-Oxide | Hydroxychloroquine N-Oxide is a derivative of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Group: Biochemicals. Grades: Highly Purified. CAS No. 1449223-88-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C18H26ClN3O2. US Biological Life Sciences. | Worldwide |
| Hydroxychloroquine O-Acetate | Quensyl-1-acetate is an analog of Hydroxychloroquine Sulfate, an antimalarial; antirheumatic; lupus erythematosus suppressant. Synonyms: 2-[[4-[ (7-Chloro-4-quinolinyl) amino]pentyl]ethylamino]ethanol 1-Acetate; 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl Acetate. Grades: > 95%. CAS No. 47493-14-1. Molecular formula: C20H28ClN3O2. Mole weight: 377.92. | |
| Hydroxychloroquine sulfate | Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro. Group: Inhibitors. Alternative Names: 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate. CAS No. 747-36-4. Molecular formula: C18H28ClN3O5S. Mole weight: 433.95. Appearance: White to off-white solid. Purity: 0.98. IUPACName: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid. Canonical SMILES: CCN (CCCC (C)NC1=C2C=CC (=CC2=NC=C1)Cl)CCO. OS (=O) (=O)O. Catalog: ACM747364-1. | |
| Hydroxychloroquine sulfate, 98% | Hydroxychloroquine sulfate, 98%. Group: other glass and ceramic materials. CAS No. 747-36-4. Product ID: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol; sulfuric acid. Molecular formula: 434g/mol. Mole weight: C18H28ClN3O5S. CCN (CCCC (C)NC1=C2C=CC (=CC2=NC=C1)Cl)CCO. OS (=O) (=O)O. InChI=1S/C18H26ClN3O. H2O4S/c1-3-22 (11-12-23)10-4-5-14 (2)21-17-8-9-20-18-13-15 (19)6-7-16 (17)18; 1-5 (2, 3)4/h6-9, 13-14, 23H, 3-5, 10-12H2, 1-2H3, (H, 20, 21); (H2, 1, 2, 3, 4). JCBIVZZPXRZKTI-UHFFFAOYSA-N. |  |
| N-Acetyl Desethyl Chloroquine-d4 | A labeled Chloroquine metabolite, also an intermediate in the preparation of labeled Chloroquine. Group: Biochemicals. Alternative Names: N-[4-[ (7-Chloro-4-quinolinyl) amino]pentyl]-N-ethyl-acetamide-d4; N-Acetyl (mono) desthylchloroquine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Didestethyl Chloroquine-d4 Phthalimide | N-Didestethyl Chloroquine-d4 Phthalimide is an intermediate in the synthesis of Hydroxychloroquine-d4 Sulfate, which is an antimalarial; antirheumatic; lupus erythematosus suppressant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C22H16D4ClN3O2. US Biological Life Sciences. | Worldwide |
| 19,20-Epoxycytochalasin C | It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro and inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (3S, 3aR, 4E, 7S, 9R, 9aR, 10aS, 11S, 11aR, 14S, 14aR)-11-(acetyloxy)-6, 7, 9, 9a, 10a, 11, 14, 14a-octahydro-3, 9-dihydroxy-1, 2, 7, 9-tetramethyl-14-(phenylmethyl)-3H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-8, 12(3aH, 13H)-dione. Grades: >99% by HPLC. CAS No. 189351-79-9. Molecular formula: C30H37NO7. Mole weight: 523.62. | |
| 19,20-Epoxycytochalasin D | It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (1S, 3S, 3aR, 4E, 7S, 9R, 9aR, 10aS, 11S, 11aR, 14S, 14aR)-11-(Acetyloxy)-3, 3a, 6, 7, 9, 9a, 10a, 11, 14, 14a-decahydro-3, 9-dihydroxy-1, 7, 9-trimethyl-2-methylene-14-(phenylmethyl)-1H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-8, 12(2H, 13H)-dione; [1aS-(1aR*, 2R*, 2aS*, 5R*, 5aS*, 6R*, 8R*, 8aS*, 9E, 12R*, 14S*, 14aS*)]-2-(Acetyloxy)-5, 5a, 6, 7, 8, 8a, 11, 12, 14, 14a-decahydro-8, 14-dihydroxy-6, 12, 14-trimethyl-7-methylene-5-(phenylmethyl)-2H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-3, 13(1aH, 4H)-dione. Grades: >99% by HPLC. CAS No. 191349-10-7. Molecular formula: C30H37NO7. Mole weight: 523.62. | |
| 2- (4- ( (7-Chloroquinolin-4-yl) amino) pentyl) isoindoline-1, 3-dione | 2- (4- ( (7-Chloroquinolin-4-yl) amino) pentyl) isoindoline-1, 3-dione is an intermediate in the synthesis of Cletoquine (C573505). Cletoquine is a metabolite of Hydroxychloroquine (H916900), an anti-malarial; anti-rheumatic; lupus erythematosus suppressant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H20ClN3O2, Molecular Weight: 393.87. US Biological Life Sciences. | Worldwide |
| 2-Methyl-1,3-dioxolane-2-propanoic Acid Methyl Ester-d2 | An intermediate in the preparation of labeled Cletoquine, Chloroquine and respective derivatives. Group: Biochemicals. Alternative Names: Methyl 2-Methyl-1,3-dioxolane-2-propionate-d2; Methyl Levulinate Ethylene Ketal-d2; Methyl 3-(2-Methyl-1,3-dioxolan-2-yl)propanoate-d2. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2-Methyl-1,3-dioxolane-2-propanol-d4 | An intermediate in the preparation of labeled Cletoquine, Chloroquine and respective derivatives. Group: Biochemicals. Alternative Names: 4,4-(Ethylenedioxy)-1-pentanol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-Acetopropanol | 3-Acetopropanol is a substrate for alcohol dehydrogenase and is an intermediate in the synthesis of Didesethyl Chloroquine (D440960), a metabolite of Chloroquine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1071-73-4. Pack Sizes: 5g, 10g. Molecular Formula: C5H10O2, Molecular Weight: 102.13. US Biological Life Sciences. | Worldwide |
| 4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol-d4 | An intermediate in the preparation of labeled Cletoquine Oxalate and Chloroquine. Group: Biochemicals. Alternative Names: 4-(4-Hydroxy-1-methyl-3,4-butylamino-d4)-7-chloroquinoline. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AMODIAQUINE | Amodiaquine is a drug which used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It has similar action to chloroquine. It is not available in the United States, but widely available in Africa. Uses: An antimalarial. Synonyms: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol; 4-[(7-Chloro-4-quinolyl)amino]-α-(diethylamino)-o-cresol; Camochin; Camoquin; Camoquinal; Camoquine; Flavoquine; Miaquin; NSC-13453; SN-10751; NSC 13453; SN 10751; NSC13453; SN10751. Grades: 95%. CAS No. 86-42-0. Molecular formula: C20H22ClN3O. Mole weight: 355.86. | |
| Amopyroquine | Antimalarial agent. The compound showed antimalarial activity similar to that of Chloroquine. Group: Biochemicals. Alternative Names: 4-[ (7-Chloro-4-quinolinyl) amino]-2- (1-pyrrolidinylmethyl) phenol; 4-[(7-Chloro-4-quinolyl)amino]-α-1-pyrrolidinyl-o-cresol; Amopyroquin; PAM-780; Propoquin. Grades: Highly Purified. CAS No. 550-81-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Anti-COVID-19 Compound Library | A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents?- Compounds contain Remdesivir, Lopinavir/Ritonavir, Chloroquine diphosphate (combination use with Remdesivir), Polydatin (bind with Mpro), etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1710. Categories: Anti-COVID-19 Compounds Libraries. | |
| Arteether | Artemotil is a fast-acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria. Uses: Amebicides. Synonyms: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran; 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, [3R-(3α, 5aβ, 6β, 8aβ, 9α, 10α, 12β, 12aR*)]-; (+)-Arteether; Artemotil; Dihydroartemisinin ethyl ether; Dihydroqinghaosu ethyl ether; NSC 665971; SM 227; β-Arteether; β-Dihydroartemisinin ethyl ether. Grades: ≥95%. CAS No. 75887-54-6. Molecular formula: C17H28O5. Mole weight: 312.41. | |
| Artemotil | Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC 50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Arteether; (+)-Arteether; Arteether. CAS No. 75887-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0770. | |
| bis- (4- methyl -1-homopiperazinyl thiocarbonyl ) disulfide | bis- (4- methyl -1-homopiperazinyl thiocarbonyl ) disulfide is a dopamine β-hydroxylase inhibitor. Also, it is a noradrenergic agents which shortens the latency of seizures induced by chloroquine. Group: Biochemicals. Grades: Highly Purified. CAS No. 26087-98-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C14H26N4S4, Molecular Weight: 378.64. US Biological Life Sciences. | Worldwide |
| Cletoquine | Cletoquine is a metabolite of Hydroxychloroquine, which is an antimalarial. Synonyms: 2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol; (±)-Desethylhydroxychloroquine; Desethyl Hydroxy Chloroquine. Grades: >95%. CAS No. 4298-15-1. Molecular formula: C16H22ClN3O. Mole weight: 307.83. | |
| Cletoquine oxalate | Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment. Group: Inhibitors. Alternative Names: 2-[[4-[ (7-Chloro-4-quinolinyl) amino]pentyl]amino]ethanol Oxalate; (+/-)-Desethylhydroxychloroquine Oxalate. CAS No. 14142-64-4. Molecular formula: C18H24ClN3O5. Mole weight: 397.85. Appearance: Brown Solid. Purity: 0.96. IUPACName: 2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol;oxalic acid. Canonical SMILES: CC(CCCNCCO)NC1=C2C=CC(=CC2=NC=C1)Cl. C(=O)(C(=O)O)O. Catalog: ACM14142644. | |
| DC661 | DC661 is an effective palmitoyl-protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and ACTS as an antilysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has significant acid hydrolysis and autophagy inhibition. Synonyms: DC661; 1872387-43-3; N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine; N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine; dc-661; C31H39Cl2N5; CHEMBL4873725; SCHEMBL19399303; BCP30743; EX-A2963; XZC38743; s8808; ZB1540; AKOS037649041; DC-661; DC 661; AC-35596; BS-16368; HY-111621; CS-0088759; D80814; 7-chloro-N-[6- ({6-[ (7-chloroquinolin-4-yl)amino]hexyl} (methyl)amino)hexyl]quinolin-4-amine. CAS No. 1872387-43-3. Molecular formula: C31H39Cl2N5. Mole weight: 552.58. | |
| Diacetylcercosporin | It is a minor hydrophobic analogue of cercosporin produced by several species of the fungal genera, cercospora and septoria. It has moderate in vitro activity against leishmania and chloroquine-sensitive strains of plasmodium falciparum. It exhibits antitumor activity. Synonyms: [S-(R*,R*)]-8,9-bis[2-(acetyloxy)propyl]-5,12-dihydroxy-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-6,11-dione; 2',2''-Diacetylcercosporin. Grades: >95% by HPLC. CAS No. 62574-06-5. Molecular formula: C33H30O12. Mole weight: 618.58. | |
| Ferroquine | Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ferrochloroquine; SSR97193. CAS No. 185055-67-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19364. | |
| Nalfurafine (TRK-820) | Nalfurafine is a κ-opioid receptor (KOR) agonist (EC50 = 0.05nM for human receptors expressed in CHO cell membranes).1 It is selective for κ-opioid over μ- and δ-opioid receptors (EC50s = 0.72 and 74.1nM, respectively). Nalfurafine (≥30ug/kg) reduces scratching behavior induced by chloroquine in mice, as well as locomotor activity when administered at a dose of 100ug/kg.2 In rats, nalfurafine (≥0.01mg/kg) reduces intracranial self-stimulation, lactic acid-induced stretching behavior, and scratching behavior induced by intradermal administration of serotonin.3 Nalfurafine is also an orexin 1 receptor (OX1R) antagonist (Ki = 250nM).4. Group: Biochemicals. Alternative Names: (2E)-N-[(5α,6 β)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(3-furanyl)-N-methyl-2-propenamide; TRK-820. Grades: Highly Purified. CAS No. 152657-84-6. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C28H32N2O5, Molecular Weight: 476.56. US Biological Life Sciences. | Worldwide |
| Nalidixic Acid, 98+% | Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid. Grades: Highly Purified. CAS No. 389-08-2. Pack Sizes: 100g, 250g, 500g, 1Kg. Molecular Formula: C12H12N2O3. US Biological Life Sciences. | Worldwide |
| Nalidixic Acid 99+% | Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicAcid; 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid; Betaxina; Cybis; Dixiben; Eucistin; NegGram; Nelidix; Win 18320; Wintomylon. Grades: Highly Purified. CAS No. 389-08-2. Pack Sizes: 25g, 100g. US Biological Life Sciences. | Worldwide |
| Nalidixic Acid-d5 | Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1-(Ethyl-d5)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid;1,4-Dihydro-1-(ethyl-d5)-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid; Betaxina-d5; Cybis-d5; Dixiben-d5; Eucistin-d5; NegGram-d5; Nelidix-d5; Win 18320-d5; Wintomylon-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Naphthoquine phosphate | Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173531-58-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17036. | |
| Piperaquine Impurity III | An impurity of Piperaquine which is a bisquinoline antimalarial drug highly active against chloroquine-resistant Plasmodium falciparum and Plasmodium vivax. Synonyms: 1,4-Bis(7-chloroquinolin-4-yl)piperazine; 31502-87-1; 7-chloro-4-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]quinoline; D355AT4JYE; Quinoline, 4,4'-(1,4-piperazinediyl)bis(7-chloro-; C22H18Cl2N4; UNII-D355AT4JYE; AN-740/37278004; SCHEMBL13891514; DTXSID30359856; MFCD01236858; AKOS016000643; DS-6306; CS-0155746; C74619; A875887; 7-chloro-4-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]quinoline. Grades: > 95%. CAS No. 31502-87-1. Molecular formula: C22H18Cl2N4. Mole weight: 409.32. | |
| Piperaquine metabolite 5 | A metabolite of Piperaquine which is a bisquinoline antimalarial drug highly active against chloroquine-resistant Plasmodium falciparum and Plasmodium vivax. Grades: > 95%. Molecular formula: C29H32Cl2N6O2. Mole weight: 567.52. | |
| Proguanil hydrochloride | Proguanil hydrochloride is the hydrochloride salt form of proguanil, which is a synthetic biguanide derivative of pyrimidine. It is used as an folate antagonist with antimalarial property. It is used to treat and prevent malaria together with chloroquine or atovaquone. lt is converted by the liver to its active metabolite, cycloguanil. It may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. It was developed by AstraZeneca and has been listed. Uses: Proguanil hydrochloride is used as an folate antagonist with antimalarial property. Synonyms: 1-(p-chlorophenyl)-5-isopropylbiguanidehydrochloride; 1-(p-chlorophenyl)-5-isopropyl-biguanidmonohydrochloride; 3359rp; chlorguanidehydrochloride; chloroguanidehydrochloride; chloroguanidinehydrochloride; diguanyl; drinupalhydrochloride. Grades: BP/EP/USP. CAS No. 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. | |
| Pyrocoll | Pyrocoll is a compound produced by Streptomyces sp. AK409 with antiparasitic and antitumor effects. It has activity against Arthrobacter bacteria, with an MIC of 1-10 μg/mL. It has a moderate anti-plasmodium effect, and its IC50 for Plasmodium facipaum is 1.19 μg/mL (standard chloroquine is 0.078 μg/mL). It also inhibits the growth of tumor cells. The IC50 pairs of HM02, HepG2 and MCF 7 cells are 0.23, 0.42 and 2.2 μg/mL, respectively. Grades: ≥95%. CAS No. 484-73-1. Molecular formula: C10H6N2O2. Mole weight: 186.17. | |
| Quinine hydrochloride | Quinine hydrochloride is a stereoisomer of quinidine that is closely related to chloroquine and has anti-malarial and muscle relaxation properties. Uses: Muscle relaxants, central. Synonyms: Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:x), (8α,9R)-; Cinchonan-9-ol, 6'-methoxy-, hydrochloride, (8α,9R)-; (1R)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride. Grades: 95%. CAS No. 7549-43-1. Molecular formula: C20H24N2O2.xHCl. Mole weight: 324.42 (free base). | |
| ROC-325 | ROC-325 is a lysosomal-mediated autophagy inhibitor. It exhibits superior preclinical anticancer activity compared with hydroxychloroquine (HCQ). Uses: Antineoplastic agents. Synonyms: ROC 325; ROC325; 1-[2-[2-[(7-chloroquinolin-4-yl)amino]ethyl-methylamino]ethylamino]-4-methylthioxanthen-9-one. CAS No. 1859141-26-6. Molecular formula: C28H27ClN4OS. Mole weight: 503.06. | |
| Sulfadoxine-d4 | Sulfadoxine-d4 is deuterium-labeled sulfadoxine. Sulfadoxine, also known as sulfamethazine, is used for bacterial infections such as hemolytic streptococci, pneumococci, and Shigella, and is now rarely used. This product combined with pyrimethamine can be used to prevent and treat malaria caused by chloroquine-resistant Plasmodium falciparum, and can also be used for the prevention of malaria. Group: Isotope-labeled environmental contaminants. Alternative Names: Sulphadoxine-d4. CAS No. 1330266-05-1. Molecular formula: C12H10D4N4O4S. Mole weight: 314.35. Appearance: Solid. Purity: ≥98.0%. Canonical SMILES: O=S (C1=C ([2H])C ([2H])=C (N)C ([2H])=C1[2H]) (NC2=NC=NC (OC)=C2OC)=O. Catalog: ACM1330266051. | |
| 1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanon | 1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanon. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1258428-71-5. Pack Sizes: 25MG. IUPAC Name: 1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propan-1-one. Molecular Formula: C29H26ClNO2. Mole Weight: 455.98. Catalog: APS1258428715. SMILES: CC (C) (O)c1ccccc1CCC (=O)c2cccc (\C=C\c3ccc4ccc (Cl)cc4n3)c2. Format: Neat. Shipping: Room Temperature. | |
| 1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene | 1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene is an impurity of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1,3-Bis[(E)-2-(7-chloroquinoline-2-yl)vinyl]benzene; 2,2'-{1,3-Phenylenedi[(E)ethene-2,1-diyl]}bis(7-chloroquinoline); (E, E) -2, 2'- (1, 3-Pphenylenedi- 2, 1- ethenediyl) bis[7- chloro-quinoline]; Montelukast Impurity 18. Grades: ≥95%. CAS No. 120578-04-3. Molecular formula: C28H18Cl2N2. Mole weight: 453.36. | |
| 1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine | 1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine is used in the studies and in the synthesis of the antimalarial activity of some tripiperaquines. Also, used in the synthesis and characterization of impurities present in an antimalarial drug piperaquine phosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 86486-21-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C36H46Cl2N8, Molecular Weight: 661.71. US Biological Life Sciences. | Worldwide |
| 1,4-bis(7-Chloroquinolin-4-yl)piperazine | 1,4-bis(7-Chloroquinolin-4-yl)piperazine, is a derivative of aminoquinolines, that have been shown to have antiparasitic, antimicrobial and antifungal activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 31502-87-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C22H18Cl2N4, Molecular Weight: 409.31. US Biological Life Sciences. | Worldwide |
| 2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol | 2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol is an impurtiy in the synthesis of Desmethyl Erlotinib which is a metabolite of Erlotinib (E625000), an anti cancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H13ClN2O4. US Biological Life Sciences. | Worldwide |
| 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol | 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: (R)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol; (1R)-1-{3-[(E)-2-(7-Chloro-2-quinoleinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]-1-propanol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, (αR)-; (R,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol. Grades: ≥95%. CAS No. 150026-75-8. Molecular formula: C29H28ClNO2. Mole weight: 457.99. | |
| 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-(1'-hydroxy-2'-methoxymethyl)propanol (Mixture of Diastereomers) | 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-(1'-hydroxy-2'-methoxymethyl)propanol (Mixture of Diastereomers) is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Uses: Intermediate in the production of montelukast metabolites. Synonyms: (1S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxy-1-(methoxymethoxy)propan-2-yl)phenyl)propan-1-ol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-[1-hydroxy-2-(methoxymethoxy)-1-methylethyl]-, (αS)-. CAS No. 184764-20-3. Molecular formula: C31H32ClNO4. Mole weight: 518.04. | |
| 2-[(3S)-3-(Acetyloxy)-1-bromo-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester | 2-[(3S)-3-(Acetyloxy)-1-bromo-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An intermediate in the synthesis of montelukast. Synonyms: methyl 2-((3S)-3-acetoxy-1-bromo-3-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate; [3S(E)]-2-[3-(Acetyloxy)-1-bromo-3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester; Benzoic acid, 2-[(3S)-3-(acetyloxy)-1-bromo-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-, methyl ester. CAS No. 184763-69-7. Molecular formula: C30H25BrClNO4. Mole weight: 578.88. | |
| 2- [4- [ (7-Chloroquinolin-4-yl) amino] pentylamino] ethanol | 2- [4- [ (7-Chloroquinolin-4-yl) amino] pentylamino] ethanol. Group: Biochemicals. Alternative Names: Cletoquine. Grades: Highly Purified. CAS No. 4298-15-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H22ClN3O. US Biological Life Sciences. | Worldwide |
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