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| Product | Description | |
|---|---|---|
| Acetylcholine-[1,1,2,2-d4] Bromide | Acetylcholine-[1,1,2,2-d4] Bromide is the labelled analogue of Acetylcholine Bromide, which is an endogenous neurotransmitter at cholinergic synapses. Synonyms: Acetylcholine-1,1,2,2-d4 Bromide; 2-(Acetyloxy)-N,N,N-trimethyl-ethan-1,1,2,2-d4-aminium Bromide; 2-(Acetyloxy)-N,N,N-trimethyl-ethanaminium-d4 Bromide; Choline Acetate-d4 (Ester) Bromide; (2-Acetyloxyethyl)trimethylammonium-d4 Bromide; Acetylcholine-d4 Bromide; Acetylcholine-d4 Hydrobromide; N,N,N-Trimethyl-2-acetoxyethylammonium-d4 Bromide; Pragmoline-d4; Tonocholin B-d4; Trimethyl(2-acetoxyethyl)ammonium-d4 Bromide. Grades: 98%; 99% atom D. CAS No. 93449-31-1. Molecular formula: C7H12D4NO2Br. Mole weight: 230.14. |  |
| Acetylcholine bromide | Acetylcholine bromide is an organic choline salt compound commonly used in neurophysiology and pharmacology experiments. It plays an important role in the nervous system, acting as a neurotransmitter that transmits signals and regulates many important physiological functions. Due to its special biological activity, Acetylcholine bromide is widely used in the study of neurotransmitters, nerve damage and muscle movement. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ACh bromide. CAS No. 66-23-9. Pack Sizes: 25 g. Product ID: HY-B0282A. |  |
| Acetylcholine chloride | Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) [1] [2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro [5]. Uses: Scientific research. Group: Natural products. Alternative Names: ACh chloride. CAS No. 60-31-1. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-B0282. | |
| Acetylcholine-d9 Bromide (2-(Acetyloxy)-N,N,N,-trimethylethanaminium-d9 Bromide, Pragmoline-d9, Tonocholin B-d9) | Cholinergic. Group: Biochemicals. Alternative Names: 2-(Acetyloxy)-N,N,N,-trimethylethanaminium-d9 Bromide; Pragmoline-d9; Tonocholin B-d9. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Acetylcholine-d9 Chloride (2-(Acetyloxy)-N,N,N,-trimethylethanaminium-d9 Chloride), Acecoline-d9, Arterocoline-d9, Miochol, Ovisot) | Cholinergic. Group: Biochemicals. Alternative Names: 2-(Acetyloxy)-N,N,N,-trimethylethanaminium-d9 Chloride); Acecoline-d9; Arterocoline-d9; Miochol; Ovisot. Grades: Highly Purified. CAS No. 344298-95-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Acetylcholine iodide | Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. Uses: Cholinergic agonists. Synonyms: Acetylcolina; 2-acetyloxyethyl(trimethyl)azanium iodide. Grades: ≥95%. CAS No. 2260-50-6. Molecular formula: C7H16NO2·I. Mole weight: 273.11. | |
| acetylcholinesterase | Acts on a variety of acetic esters; also catalyses transacetylations. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3497; acetylcholinesterase; EC 3.1.1.7; 9000-81-1; true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Cat No: EXWM-3497. |  |
| Acetylcholinesterase, Electric eel | Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-81-1. Pack Sizes: 500 U. Product ID: HY-P2860A. | |
| Acetylcholinesterase Human, Recombinant | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Activity: > 1,000 units/mg protein (Lowry). Storage: -20°C. Form: Lyophilized powder containing phosphate buffer salt. Source: HEK 293 cells. Species: Human. Cat No: NATE-0020. | |
| Acetylthiocholine bromide | Acetylthiocholine bromide is a widely utilized compound in the biomedical industry, serving as a fundamental substrate to gauge cholinesterase activity. Its primary purpose is the evaluation of cholinesterase inhibition or reactivation. Synonyms: (2-Mercaptoethyl)trimethylammonium bromide acetate. CAS No. 25025-59-6. Molecular formula: C7H16BrNOS. Mole weight: 242.18. | |
| Acetylthiocholine iodide | Acetylthiocholine iodide can be used as a substrate for certain enzymes, such as cholinesterase, etc., and can be used to determine the activity level of these enzymes. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-Acetylthiocholine iodide; ATCh iodide. CAS No. 1866-15-5. Pack Sizes: 10 g. Product ID: HY-D0904. | |
| choline O-acetyltransferase | Propanoyl-CoA can act, more slowly, in place of acetyl-CoA. Group: Enzymes. Synonyms: choline acetylase; choline acetyltransferase. Enzyme Commission Number: EC 2.3.1.6. CAS No. 9012-78-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2239; choline O-acetyltransferase; EC 2.3.1.6; 9012-78-6; choline acetylase; choline acetyltransferase. Cat No: EXWM-2239. | |
| Native Electrophorus electricus (electric eel) Acetylcholinesterase | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Type vi-s, lyophilized powder, 200-1000 units/mg protein; type v-s, lyophilized powder, > 1000 units/mg protein. Applications: The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. the enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride. Group: Enzymes. Synonyms: true c. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: 280 kDa. Activity: > 1 ,000 units/mg protein; 200-1 ,000 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Electrophorus electricus (electric eel). true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0018. | |
| Native Human erythrocytes Acetylcholinesterase | Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel. Applications: Acetylcholinesterase (ache) from creative enzymes has been used in the structure-activity study of phosphoramido acid esters as inhibitors of ache. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholines. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: ~80 kDa. Activity: > 500 units/mg protein (BCA). Storage: 2-8°C. Form: buffered aqueous solution. Solution in 20 mM HEPES, pH 8.0, containing 0.1% TRITON X-100. Source: Human erythrocytes. Species: Human. true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0019. | |
| 1-(3-Methoxyphenyl)ethanol | A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanol; 1-(3-methoxyphenyl)ethanol. Grades: 99 %. CAS No. 23308-82-9. Molecular formula: C9H12O2. Mole weight: 152.19. | |
| 3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride | 3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone Hydrochloride is a reactant used in the preparation of choline acetyltransferase (ChA) inhibitors. Group: Biochemicals. Alternative Names: 3-Dimethylamino-1-(naphthalen-1-yl)propan-1-one Hydrochloride. Grades: Highly Purified. CAS No. 5409-58-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 3'-Methoxyacetophenone | A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanone. Grades: 99 %. CAS No. 586-37-8. Molecular formula: C9H10O2. Mole weight: 150.17. | |
| 4-(1-(dimethylamino)ethyl)phenol hydrochloride | An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Dimethyl-alpha-(4-hydroxyphenyl)ethylamine hydrochloride; p-(1-(Dimethylamino)ethyl)phenol hydrochloride; Rivastigmine Impurity 11. CAS No. 1049692-05-8. Molecular formula: C10H16ClNO. Mole weight: 201.69. | |
| Aceclidine, Hydrochloride (3-Acetyloxy-1-azabicyclo[2, 2, 2]octane, Hydrochloride) | Aceclidine is a synthetic analogue of arecoline, a natural cholinomimetic alkaloid. Aceclidine acts as an agonist at cholinergic receptors and has therapeutic use to reduce intraocular pressure in glaucoma. Group: Biochemicals. Alternative Names: 3-Acetyloxy-1-azabicyclo[2, 2, 2]octane, Hydrochloride. Grades: Highly Purified. CAS No. 6109-70-2. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (±)-Acetylcarnitine chloride | (±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with cholinergic properties. (±)-Acetylcarnitine chloride is an important intermediate in lipid metabolism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetyl dl-carnitine chloride. CAS No. 2504-11-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100907. | |
| (±)-Acetylcarnitine chloride | (±)-Acetylcarnitine chloride is a weak cholinergic receptor agonist. It is used as an important intermediate in lipid metabolism. Synonyms: Acetyl-DL-carnitine hydrochloride; Acetyl-L-carnitine hydrochloride; O-Acetyl-L-carnitine hydrochloride; O-Acetyl-L-carnitine HCl. CAS No. 2504-11-2. Molecular formula: C9H18ClNO4. Mole weight: 239.70. | |
| Acetyl-L-carnitine chloride | Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors. Applications: A cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Group: Coenzymes. Synonyms: R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride. CAS No. 5080-50-2. Purity: ≥99%. Mole weight: 239.7. Form: Solid. R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride; Acetyl-L-carnitine chloride; 5080-50-2. Cat No: COEC-005. | |
| acetylsalicylate deacetylase | Not identical with EC 3.1.1.1 (carboxylesterase), EC 3.1.1.2 (arylesterase), EC 3.1.1.7 (acetylcholinesterase) or EC 3.1.1.8 (cholinesterase). The activity of the liver cytosol enzyme is highest with acetyl esters of aryl alcohols, and thioesters are also hydrolysed; the microsomal enzyme also hydrolyses some other negatively charged esters, with highest activity on esters of salicylate with long-chain alcohols. Group: Enzymes. Synonyms: aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Enzyme Commission Number: EC 3.1.1.55. CAS No. 87348-04-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3483; acetylsalicylate deacetylase; EC 3.1.1.55; 87348-04-7; aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Cat No: EXWM-3483. | |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554. | |
| Aldicarb sulfone | Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17530. | |
| α-NETA | α-NETA is a stable, non-competitive, and slowly reversible inhibitor of choline acetyltransferase (ChAT) with IC50 value of 9 μM. It mildly inhibits cholinesterases and carnitine acetyltransferase. Synonyms: HY-124957; 2-Naphthoylethyltrimethylammonium. Grades: ≥97%. CAS No. 31059-54-8. Molecular formula: C16H20NO·I. Mole weight: 369.2. | |
| Amifampridine | Amifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. It is used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. Uses: Neuromuscular agents. Synonyms: pyridine-3,4-diamine. Grades: > 98 %. CAS No. 54-96-6. Molecular formula: C5H7N3. Mole weight: 109.13. | |
| Amifampridine Phosphate | Amifampridine is a drug, predominantly used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. Uses: Predominantly in the treatment of a number of rare muscle diseases. Synonyms: phosphoric acid;pyridine-3,4-diamine. Grades: ≥98%. CAS No. 446254-47-3. Molecular formula: C5H10N3O4P. Mole weight: 207.12. | |
| AP2238 | AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6, 7-dimethoxy-3- (4- ( (methyl (phenylmethyl)amino)methyl)phenyl)-; 3-[4- (N-Benzyl-N-methylaminomethyl)phenyl]-6, 7-dimethoxy-2H-1-benzopyran-2-one. Grades: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. | |
| Atropine sulfate monohydrate | Atropine sulfate is a cholinergic drug that inhibits the enzyme acetylcholinesterase. It is used to treat bradycardia and to reduce the spasms of smooth muscle, including those of the bronchi, gastrointestinal tract, uterus, bladder and urinary passages. Atropine sulfate also has been used as an antidote for poisoning by organophosphates and other cholinesterase inhibitors. The drug is readily absorbed from the gastrointestinal tract, with peak plasma concentrations occurring about one hour after ingestion. The half-life is about three hours. The major route of elimination is via renal excretion of unchanged drug in urine. Group: Other alkaloids. Alternative Names: a-(Hydroxymethyl)benzeneacetic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate hydrateAtropine sulfate hydrateAtr opisol. CAS No. 5908-99-6. Molecular formula: C34H50N2O11S. Mole weight: 694.83 g/mol. Canonical SMILES: CN1[C@@H]2CC[C@H]1CC (C2)OC (=O)C (CO)C3=CC=CC=C3. CN1[C@@H]2CC[C@H]1CC (C2)OC (=O)C (CO)C3=CC=CC=C3. O. OS (=O) (=O)O. Catalog: ACM5908996-2. |  |
| Benzoylcholine chloride | Benzoylcholine chloride, a pivotal pharmaceutical compound in the biomedical sector, unveils its paramount significance. Its foremost application revolves around targeting neurological disorders, particularly myasthenia gravis. By acting as an inhibitory force on the formidable enzyme acetylcholinesterase, it exudes its prowess in augmenting cholinergic neurotransmission. Synonyms: Benzoylcholine chloride; 2964-09-2; [2-(benzoyloxy)ethyl]trimethylazanium chloride; 2-(benzoyloxy)-n,n,n-trimethylethanaminium chloride; 2-benzoyloxyethyl(trimethyl)azanium; chloride; Ethanaminium, 2-(benzoyloxy)-N,N,N-trimethyl-, chloride (1:1); (2-Hydroxyethyl)trimethylammonium chloride benzoate; Choline, chloride, benzoate; EINECS 221-000-9; 2-Benzoyloxyethyltrimethylammonium chloride; 2-(Benzyloxy)-N,N,N-trimethylethanaminium chloride; 2-(Benzyloxy)-N,N,N-trimethylethanaminimum chloride; SCHEMBL2356481; Ammonium, (2-hydroxyethyl)trimethyl-, chloride, benzoate; Ethanaminium, 2-(benzyloxy)-N,N,N-trimethyl-, chloride; DTXSID70952108; HMS1537M05; MFCD00011786; AKOS015833142; HY-W127639; AS-71168; B0107; CS-0185839; D88604; J-017588; 2-(Benzoyloxy)-N,N,N-trimethylethan-1-aminium chloride. CAS No. 2964-9-2. Molecular formula: C12H18ClNO2. Mole weight: 243.73. | |
| Benzoyl choline iodide | Benzoyl choline iodide is an esteemed biomedicine renowned for its remarkable anticholinesterase activity. This unparalleled compound exerts its therapeutic prowess by indefatigably suppressing the action of acetylcholinesterase, culminating in a momentous elevation of acetylcholine levels and an amelioration of neurochemical transmission. CAS No. 17518-43-3. Molecular formula: C12H18INO2. Mole weight: 335.18. | |
| bis(7)-Tacrine | Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grades: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6. | |
| Butyrylcholine perchlorate | Butyrylcholine perchlorate, a potent biomedical compound, finds its application in both research and clinical environments. Serving as an acetylcholine receptor agonist, this cholinergic substance bravely delves into unraveling the intricate mechanisms governing cholinergic neurotransmission. With an unwavering dedication to scientific exploration, it illuminates the enigmatic role played by this neurotransmission in afflictions such as Alzheimer's disease, myasthenia gravis, and an array of formidable neuromuscular disorders. Synonyms: BUTYRYLCHOLINE PERCHLORATE; Trimethyl(2-(1-oxobutoxy)ethyl)ammonium perchlorate; EINECS 243-700-3; 2-butanoyloxyethyl(trimethyl)azanium; perchlorate; 566ZY7YY3K; DTXSID80174172; [2-(butanoyloxy)ethyl]trimethylazanium perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate (1:1). CAS No. 20292-68-6. Molecular formula: C9H20ClNO6. Mole weight: 273.71. | |
| Chavicol | Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase ( Cholinesterase (ChE) ), with an IC 50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: p-Hydroxyallylbenzene. CAS No. 501-92-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W159754. | |
| Choline bitartrate | Choline bitartrate is a vitamin-like essential nutrient , can affect diseases such as liver disease, atherosclerosis and neurological disorders [1] [2]. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism [3]. Uses: Scientific research. Group: Natural products. CAS No. 87-67-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101036. | |
| Choline Bitartrate | Choline Bitartrate is the salt form of choline with better absorption. Choline is a vitamin B analog obtained from diet by humans. Choline plays a role in the formation of cell membrane formation and acetylcholine. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Butanedioic acid, 2,3-dihydroxy-(2R,3R)-, ion(1-), 2-hydroxy-N,N,N-trimethylethanaminium; Butanedioic acid, 2,3-dihydroxy-[R-(R*,R*)]-, ion(1-), 2-hydroxy-N,N,N-trimethylethanaminium; Choline tartrate; Choline, hydrogen tartrate; Choline, tartrate (1:1) (salt); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with (2R,3R)-2,3-dihydroxybutanedioic acid (1:1); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with [R-(R*,R*)]-2,3-dihydroxybutanedioic acid (1:1); Tartaric acid, ion(1-), choline; (2-Hydroxyethyl)trimethylammonium bitartrate. Grades: 95%. CAS No. 87-67-2. Molecular formula: C9H19NO7. Mole weight: 253.25. | |
| Cholinesterase, Horse serum | Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.1.1.8; BCHE, Horse serum. CAS No. 9001-8-5. Pack Sizes: 100 U. Product ID: HY-P2798. | |
| Coluracetam | Coluracetam (MKC-231) is an orally taken choline uptake enhancer. Coluracetam can improve the reduced acetylcholine levels in the hippocampus of rats and mice, enhancing learning difficulties, memory deficits, and cognitive impairments. Coluracetam induces a lower degree of hepatic venous hyperglycemia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MKC-231. CAS No. 135463-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17553. | |
| Cycrimine | Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77-39-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119918. | |
| dAP2 (Nic) | dAP2 (Nic) presents itself as a worthy consideration in cholinergic signaling modulation. Its focus on targeting the nicotinic acetylcholine receptor exhibits prospects for application in treating perturbed signaling ailments like Alzheimer's disease and schizophrenia. Synonyms: P1-[5'-(2'-Deoxy-adenosyl)] P2-[5'-(1-β D-Ribofuranosyl-nicotinamide)] diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H27N7O13P2 (free acid). Mole weight: 647.43 (free acid). | |
| (±)-Decanoylcarnitine chloride | Homolog of acetylcarnitine chloride and (±)-Acetylcarnitine chloride is a weak AChR (cholinergic) agonist. Synonyms: (+/-)-Decanoylcarnitine chloride; (3-carboxy-2-decanoyloxypropyl)-trimethylazanium chloride. Grades: ≥98% by HPLC. CAS No. 14919-36-9. Molecular formula: C17H34ClNO4. Mole weight: 351.91. | |
| Demecarium bromide | Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Synonyms: 3, 3'-[1, 10-decanediylbis[ (methylimino)carbonyloxy]]bis[N, N, N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. Grades: ≥95%. CAS No. 56-94-0. Molecular formula: White Solid. Mole weight: 716.59. | |
| diacylglycerol cholinephosphotransferase | 1-Alkyl-2-acylglycerol can act as acceptor; this activity was previously listed separately. Group: Enzymes. Synonyms: phosphorylcholine-glyceride transferase; alkylacylglycerol cholinephosphotransferase; 1-alkyl-2-acetylglycerol cholinephosphotransferase; cholinephosphotransferase; CPT; alkylacylglycerol choline phosphotransferase; diacylgl. Enzyme Commission Number: EC 2.7.8.2. CAS No. 9026-13-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3319; diacylglycerol cholinephosphotransferase; EC 2.7.8.2; 9026-13-5; phosphorylcholine-glyceride transferase; alkylacylglycerol cholinephosphotransferase; 1-alkyl-2-acetylglycerol cholinephosphotransferase; cholinephosphotransferase; CPT; alkylacylglycerol choline phosphotransferase; diacylglycerol choline phosphotransferase; 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase; CDP-choline diglyceride phosphotransferase; cytidine diphosphocholine glyceride transferase; cytidine diphosphorylcholine diglyceride transferase; phosphocholine diacylglyceroltransferase; sn-1,2-diacylglycerol cholinephosphotransferase; 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase; CDP choline:1,2-diacylglycerol cholinephosphotransferase; CDP-choline:1,2-diacylglycerol cholinephosphotransferase. Cat No: EXWM-3319. | |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grades: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49. | |
| (-)-Donepezil | (-)-Donepezil is one of Donepezil isomers. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Cholinesterase inhibitors; nootropic agents. Synonyms: (S)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; (S)-Donepezil; (S)-Aricept; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. Grades: ≥95%. CAS No. 142057-80-5. Molecular formula: C24H29NO3. Mole weight: 379.49. | |
| Fustin | Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone. CAS No. 20725-03-5. Pack Sizes: 1 mg. Product ID: HY-N8376. | |
| Galanthamine | Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Synonyms: NSC 100058; NSC100058; NSC-100058; BRN 0093736; BRN0093736; BRN-0093736; Galantamine; Reminyl; Lycoremine; (-)-Galanthamine; Galantamin; Lycoremin; Jilkon; Nivalin; Razadyne; Galantamina; Galanthaminum; Galantaminum; Razadyne ER; Galantaminum. Grades: >98%. CAS No. 357-70-0. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
| Garcinol | Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica , exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC 50 s of 0.66 μM and 7.39 μM, respectively [1]. Garcinol also inhibits histone acetyltransferases ( HATs , IC 50 = 7 μM) and p300/CPB-associated factor ( PCAF , IC 50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 78824-30-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107569. | |
| Hemicholinium 3 | Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a K i value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh) [1]. Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [ 3 H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hemicholinium dibromide. CAS No. 312-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B2152. | |
| Hexafluorenium bromide | Hexafluronium bromide is.a cholinesterase inhibitor used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. Uses: Acetylcholine receptor. Synonyms: Mylaxen; 9H-fluoren-9-yl-[6-[9H-fluoren-9-yl(dimethyl)azaniumyl]hexyl]-dimethylazanium;dibromide. Grades: ≥98%. CAS No. 317-52-2. Molecular formula: C36H42N2.2Br. Mole weight: 662.54008. | |
| keratan sulfotransferase | Sulfation takes place at the 6-position of galactosyl and N-acetylglucosaminyl residues in keratan, a proteoglycan. Not identical with EC 2.8.2.5 (chondroitin 4-sulfotransferase), EC 2.8.2.6 (choline sulfotransferase) or EC 2.8.2.17 (chondroitin 6-sulfotransferase). Group: Enzymes. Synonyms: 3'-phosphoadenylyl keratan sulfotransferase; keratan sulfate sulfotransferase; 3'-phosphoadenylylsulfate:keratan sulfotransferase. Enzyme Commission Number: EC 2.8.2.21. CAS No. 62168-79-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3380; keratan sulfotransferase; EC 2.8.2.21; 62168-79-0; 3'-phosphoadenylyl keratan sulfotransferase; keratan sulfate sulfotransferase; 3'-phosphoadenylylsulfate:keratan sulfotransferase. Cat No: EXWM-3380. | |
| (+)-Melochinine | (+)-Melochinine is an alkaloid found in plants of the Piperaceae family. It has been shown to have a cholinesterase inhibitory activity and to be hepatoprotective. (+)-Melochinine is metabolized by esterases and can act as a substitute for acetylcholine. The pharmacological profile of (+)-melochinine has been studied in animals, which revealed that it does not have any effect on the central nervous system. In addition, (+)-melochinine has antibacterial and antipyretic properties. It interacts with pyramidal cells in the brain stem, which are responsible for controlling muscle movement, and may cause muscle spasms or paralysis. Group: Other alkaloids. CAS No. 70001-21-7. Molecular formula: C19H33NO3. Mole weight: 323.47 g/mol. Canonical SMILES: CC1=C (C (=O)C=C (N1)CCCCCCCCCC[C@@H] (C)O)OC. Catalog: ACM70001217. | |
| Methacholine chloride | Methacholine chloride, a synthetic choline ester, is pharmaceutical agent acting as a β2-adrenergic agonist used in the treatment of pulmonary and respiratory diseases including asthma. Uses: Used in the treatment of pulmonary and respiratory diseases including asthma. Synonyms: (2-Acetoxypropyl)trimethylammonium chloride; Acetyl--methylcholine chloride. Grades: ≥98%. CAS No. 62-51-1. Molecular formula: C8H18ClNO2. Mole weight: 195.69. | |
| Mivacurium | Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, which results in a block of neuromuscular transmission. It is used in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during mechanical ventilation or surgery. Uses: Mivacurium is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. Synonyms: 2, 2'-[ (1, 8-Dioxo-4-octene-1, 8-diyl) bis (oxy-3, 1-propanediyl) ]bis[1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-[ (3, 4, 5-trimethoxyphenyl) methyl]isoquinolinium; Isoquinolinium, 2,2'-((1,8-dioxo-4-octene-1,8-diyl)bis(oxy-3,1-propanediyl))bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-((3,4,5-trimethoxyphenyl)methyl)-;Bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;BW-B-1090U;Mivacron;(1R,1'R)-2,2'-((((E)-oct-4-enedioyl)bis(oxy))bis(propane-3,1-diyl))bis(6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium). Grades: 95%. CAS No. 106791-40-6. Molecular formula: C58H80N2O14. Mole weight: 1029.28. | |
| Mivacurium chloride | Mivacurium is a nicotinic acetylcholine receptors (nAChRs) antagonist and a non-depolarizing neuromuscular-blocking drug metabolized by plasma cholinesterase. Grades: ≥95%. CAS No. 106861-44-3. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.2. | |
| (±)-Myristoylcarnitine chloride | (±)-Myristoylcarnitine chloride is a homolog of Acetylcarnitine Chloride, which is a weak cholinergic agonist. Acylcarnitines are important intermediates in lipid metabolism. Synonyms: 3-Carboxy-N,N,N-trimethyl-2-[(1-oxotetradecyl)oxy]-1-propanaminium Chloride; Myristoyl Carnitine Hydrochloride; Myristoylcarnitine Chloride. Grades: ≥97% by HPLC. CAS No. 14919-38-1. Molecular formula: C21H42ClNO4. Mole weight: 408.02. | |
| NAP226-90 (Rivastigmine EP Impurity A) | An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: (S)-3-[1-(Dimethylamino)ethyl]phenol; Rivastigmin USP Related Compound C; NAP-226-90. Grades: > 95%. CAS No. 139306-10-8. Molecular formula: C10H15NO. Mole weight: 165.24. | |
| Native Equine Butyrylcholinesterase | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. This product is prepared from equine serum using ammonium sulfate fractionation and supplied as a lyophilized powder. Applications: Butyrylchol...vestigations into selective inhibitors may provide a clearer picture of the physiological role of bche in both healthy and diseased individuals. this product has been used for the screening of cholineesterase inhibitors in selected fruits and vegetables, for restoring cognitive function and improving memory. it has also been used to develop a butyrylcholinesterase and choline oxidase immobilized bio-sniffer for the detection of nicotine. nicotine inhibits bche activity. a decrease in the byproducts of bche activity reflects the volume of nicotine. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; | |
| Native Human Butyrylcholinesterase | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. Applications: Butyrylcholinesterase (bche) is a serine hydrolase that shares substantial structural similarities with acetylcholinesterase (ache) but has different substrate and inhibitor specificities. bche is found in the serum, hemopoietic cells, liver, lung, heart and the central nervous system of vertebrates. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Activity: > 50 U/mg protein. Source: Human serum. Species: Human. Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Cat No: NATE-0093. | |
| N-Desmethyl Rivastigmine | A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester. Grades: > 95%. CAS No. 1070660-34-2. Molecular formula: C13H20N2O2. Mole weight: 236.32. | |
| N-Dimethyl Rivastigmine (Rivastigmine EP Impurity B) | A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Dimethylcarbamic Acid 3-[1-(Dimethylamino)ethyl]phenyl Ester; Dimethylcarbamic Acid m-[1-(Dimethylamino)ethyl]phenyl Ester; m-[1- (dimethylamino) ethyl]phenolDimethylcarbamate (ester); USP Rivastigmine Related Compound B. Grades: > 95%. CAS No. 25081-93-0. Molecular formula: C13H20N2O2. Mole weight: 236.32. | |
| Neostigmine | Neostigmine is a parasympathomimetic compound, which acts as a reversible acetylcholinesterase inhibitor. It is used in the treatment of myasthenia gravis, ogilvie syndrome and urinary retention without the presence of a blockage. It is also used to reverse the effects of muscle relaxants such as gallamine and tubocurarine. It is in the cholinergic family of medications and works by blocking the action of acetylcholinesterase and therefore increases the levels of acetylcholine. It does not cross the blood-brain barrier. Uses: Neostigmine is used in the treatment of myasthenia gravis, ogilvie syndrome and urinary retention without the presence of a blockage. it is also used to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Synonyms: CCRIS 3079; CCRIS3079; CCRIS-3079; 3-[[(Dimethylamino)carbonyl]oxy]-N, N, N-trimethylbenzenaminium; Eustigmin; Eustigmine; Vagostigmine; Prostigmin; Polstigmine. Grades: 98%. CAS No. 59-99-4. Molecular formula: C12H19N2O2. Mole weight: 223.33. | |
| Neostigmine Bromide | Neostigmine (Eustigmin) Bromide is an orally active and reversible cholinesterase inhibitor that acts on myasthenia gravis to prolong and intensify the muscarinic and nicotinic effects of acetylcholine. Neostigmine Bromide can be used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eustigmin bromide; Neoserine bromide. CAS No. 114-80-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0423. | |
| NETA alpha (2- (alpha-Naphthoyl) ethyltrimethylammonium iodide) | Potent fluorescent inhibitor of choline acetyltransferase. Group: Biochemicals. Alternative Names: 2- (alpha-Naphthoyl) ethyltrimethylammonium iodide. Grades: Highly Purified. CAS No. 31059-54-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| N-Methyl Rivastigmine Chloride | A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: N-Methyl Rivastigmine Chloride; (S)-1-(3-{[Ethyl(methyl)carbamoyl]oxy}phenyl)-N,N,N-trimethylethanaminium chloride; Rivastigmine Related Compound E; Rivastigmine Related Compound E as Chloride. Grades: > 95%. Molecular formula: C15H25N2O2. Cl. Mole weight: 300.83. | |
| (±)-Octanoylcarnitine chloride | A homolog of acetylcarnitine chloride. Acetylcarnitine chloride is a weak cholinergic agonist. Acylcarnitines are important intermediates in lipid metabolism. Synonyms: (3-Carboxy-2-hydroxypropyl)trimethylammonium Chloride, Octanoate (7CI); 3-Carboxy-N,N,N-trimethyl-2-[(1-oxooctyl)oxy]-1-propanaminium, Chloride (9CI); (3-carboxy-2-hydroxypropyl)trimethylammonium, Chloride, Octanoate (8CI); Octanoic Acid, Ester with (3-Carboxy-2-hydroxypropyl)trimethylammonium Chloride; Octanoyl Carnitine Hydrochloride; Octanoyl-dl-carnitine Hydrochloride; Octanoylcarnitine Chloride. Grades: ≥95%. CAS No. 18822-86-1. Molecular formula: C15H30ClNO4. Mole weight: 323.86. | |
| O-Desmethyl galanthamine b-D-glucuronide | O-Desmethyl galanthamine b-D-glucuronide, a prominent biomedical substance, is efficaciously employed for combating Alzheimer's disease. This metabolite of galanthamine exerts its therapeutic effects by proficiently inhibiting acetylcholinesterase, thereby facilitating the augmentation of cholinergic neurotransmission. Its remarkable properties even hold potential to enhance cognitive abilities, memory retention, and overall functionality in individuals afflicted with Alzheimer's disease. Synonyms: (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-6-hydroxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-3-yl b-D-glucopyranosiduronic acid. CAS No. 464189-54-6. Molecular formula: C22H27NO9. Mole weight: 449.45. | |
| Physostigmine | Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Eserine. CAS No. 57-47-6. Pack Sizes: 1 mg. Product ID: HY-N6608. | |
| Physostigmine salicylate | Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eserine salicylate. CAS No. 57-64-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1266. | |
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