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| Product | Description | |
|---|---|---|
| 1,5,6,7-Tetra-O-benzylvoglibose | 1,5,6,7-Tetra-O-benzylvoglibose, a carbohydrate-derived substance employed in the field of biomedicine, has been exhaustively researched due to its potential as an anti-diabetic medication in the fight against type 2 diabetes. This compound is ingeniously engineered to obstruct alpha-glucosidase enzymes, which play a critical role in carbohydrate digestion. Its ability to curtail postprandial blood glucose levels is a promising therapeutic choice in the management of type 2 diabetes. Synonyms: TBV. CAS No. 115250-39-0. Molecular formula: C38H45NO7. Mole weight: 627.77. |  |
| 1,5-Anhydro-4,6-O-benzylidene-2-O-toluoyl-D-glucitol | 1,5-Anhydro-4,6-O-benzylidene-2-O-toluoyl-D-glucitol, a chemical compound praised for its antidiabetic properties, is typically utilized as a key ingredient in the development of groundbreaking medications. This compound facilitates effective glucose management by selectively targeting alpha-glucosidase enzymes, an important regulatory mechanism for optimal blood sugar levels in the body of patients afflicted with diabetes. CAS No. 156715-23-0. Molecular formula: C21H22O6. Mole weight: 370.4. | |
| 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-toluoyl-D-glucitol | 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-toluoyl-D-glucitol, widely recognized as a pivotal compound within the biomedical realm, assumes a significant role in the treatment of diverse ailments, foremost among them being diabetes. Its unparalleled capability to regulate blood sugar levels renders it an indispensable entity. This invaluable product seamlessly inhibits α-glucosidase enzymes, thereby facilitating enhanced glycemic control. Synonyms: 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-(4-methylbenzoyl)-D-ribo-hexitol. CAS No. 149312-19-6. Molecular formula: C21H22O5. Mole weight: 354.4. | |
| 1,5-Anhydro-4,6-O-benzylidene-3-O-[2,4-dichlorophenyl]thiocarbonyloxy-2-O-toluoyl-D-glucitol | 1,5-Anhydro-4,6-O-benzylidene-3-O-[2,4-dichlorophenyl]thiocarbonyloxy-2-O-toluoyl-D-glucitol, a novel compound, has shown potent inhibition of alpha-glucosidase enzymes, making it a promising candidate for diabetes therapy. By reducing carbohydrate absorption, it is expected to effectively lower blood glucose levels. Its potential as a therapeutic agent for type 2 diabetes warrants further investigation, given its unique chemical profile and mechanism of action. Molecular formula: C28H24Cl2O7S. Mole weight: 575.46. | |
| 1-alkylglycerophosphocholine O-acetyltransferase | This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. This enzyme participates in ether lipid metabolism. Group: Enzymes. Synonyms: acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase; acetyl-CoA:lyso-PAF acetyltransferase; 1-alkyl-2-lysolecithin acetyltransferase; acyl-CoA:1-alkyl-sn-glycero-3-phosphoc. Enzyme Commission Number: EC 2.3.1.67. CAS No. 76773-96-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2247; 1-alkylglycerophosphocholine O-acetyltransferase; EC 2.3.1.67; 76773-96-1; acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase; acetyl-CoA:lyso-PAF acetyltransferase; 1-alkyl-2-lysolecithin acetyltransferase; acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase; blood platelet-activating factor acetyltransferase; lyso-GPC:acetyl CoA acetyltransferase; lyso-platelet activating factor:acetyl-CoA acetyltransferase; lysoPAF:acetyl CoA acetyltransferase; PAF acetyltransferase; platelet-activating factor acylhydrolase; platelet-activating factor-synthesizing enzyme; 1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase; lyso-platelet-activating factor:acetyl-CoA acetyltransferase. Cat No: EXWM-2247. |  |
| 1-Chloro-1-deoxy-scyllo-inositol | 1-Chloro-1-deoxy-scyllo-inositol, a promising therapeutic candidate for the treatment of metabolic conditions like obesity and diabetes, exerts its action by suppressing the enzymatic activity of α-glucosidase, the key enzyme involved in the hydrolysis of carbohydrates into glucose, which subsequently limits the intestinal absorption of glucose, ultimately resulting in a reduced blood glucose level. Molecular formula: C6H11ClO5. Mole weight: 198.60. | |
| 1-Deoxy-D-sorbose | 1-Deoxy-D-sorbose, a remarkable biomedical substance, presents itself as a promising therapeutic tool in the management of diabetes. By means of obstructing the action of aldose reductase, a pivotal enzyme implicated in diabetic complications, this compound adeptly modulates blood glucose levels. Synonyms: methylxylose. Molecular formula: C6H12O5. Mole weight: 164.16. | |
| 1-Deoxy-L-talitol | 1-Deoxy-L-talitol is a biomedical compound utilized in the treatment of various diseases. This product acts as an inhibitor and has shown promising effects in treating metabolic disorders and diabetes. By suppressing specific enzyme activities, it regulates glucose metabolism, ultimately aiding in controlling blood glucose levels. Its potential therapeutic benefits make 1-Deoxy-L-talitol an essential component in the biomedicine industry. Molecular formula: C6H14O5. Mole weight: 166.17. | |
| 2,2,2-trifluoroethyl formate | Lisinopril Impurity 12 (2,2,2-trifluoroethyl formate) is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: Lisinopril Impurity 12. Grades: 97 % (HPLC). CAS No. 32042-38-9. Molecular formula: C3H3F3O2. Mole weight: 128.05. | |
| 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt | D-Glycerate 2,3-diphosphate (DPG), cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. 2,3-diphosphoglycerate (DPG) may be used as a reference in assays that measure DPG levels to indicate the health status of erythrocytes/red blood cells (RBC). Applications: Used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. Group: Coenzymes. Synonyms: D-Glycerate 2,3-diphosphate pentacyclohexylamine salt. CAS No. 62868-79-5. Purity: ≥95%. Mole weight: 761.91. Appearance: Powder. Form: Solid. D-Glycerate 2,3-diphosphate pentacyclohexylamine salt; 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt; 62868-79-5. Cat No: COEC-080. | |
| 2-((5-Chloropyridin-2-yl)amino)-2-oxoacetic Acid | 2-((5-Chloropyridin-2-yl)amino)-2-oxoacetic Acid is a reactant or reagent used in the synthesis of the blood coagulating enzyme factor Xa (FXa) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 552850-73-4. Pack Sizes: 1g, 5g. Molecular Formula: C7H5ClN2O3, Molecular Weight: 200.58. US Biological Life Sciences. |  Worldwide |
| 2-Acetamido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol | 2-Acetamido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol, a synthetically derived organic compound, serves as a potent inhibitor of glucosidase enzymes in the biomedical sector. In clinical settings, this molecule aids in regulating excessive blood glucose levels in type 2 diabetes patients, in addition to mitigating symptoms of various metabolic disorders. The multifunctional nature of this compound has demonstrated its potential in expanding therapeutic avenues. Molecular formula: C20H28N2O6. Mole weight: 392.45. | |
| 2-Acetamido-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol | 2-Acetamido-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol is a synthetic compound used in the biomedical industry for treating type 2 diabetes. It works by inhibiting alpha-glucosidase, an enzyme that breaks down carbohydrates in the small intestine, slowing down the absorption of glucose and reducing blood sugar level. Synonyms: 2-ACETAMIDO-4,6-O-BENZYLIDENE-N-(TERT-BUTOXYCARBONYL)-1,2,5-TRIDEOXY-1,5-IMINO-D-GLUCITOL; tert-butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydro-[1,3]dioxino[5,4-b]pyridine-5-carboxylate; tert-Butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenylhexahydro-5H-[1,3]dioxino[5,4-b]pyridine-5-carboxylate; starbld0032901; DTXSID00565023; tert-Butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenylhexahydro-2H,5H-[1,3]dioxino[5,4-b]pyridine-5-carboxylate. CAS No. 1221795-90-9. Molecular formula: C20H28N2O6. Mole weight: 392.45. | |
| 2-Amino-2-deoxy-glucitol | 2-Amino-2-deoxy-glucitol, also known as miglitol, is a pharmacological agent used in the management of hyperglycemia associated with type 2 diabetes mellitus. Its mechanism of action involves the inhibition of alpha-glucosidase enzymes responsible for the breakdown of carbohydrates in the small intestine. This leads to a delay in the absorption of glucose, resulting in lower postprandial blood glucose levels. Despite its efficacy, miglitol may cause gastrointestinal side effects such as flatulence and diarrhea and is best used in combination with other antidiabetic agents. Synonyms: 5-aminohexane-1,2,3,4,6-pentol; 2351-14-6; SCHEMBL3797037; DTXSID60313360; NSC269409; NSC-269409. CAS No. 2351-14-6. Molecular formula: C6H15NO5. Mole weight: 181.19. | |
| (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol | (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol is an incredibly potent antiviral compound, employed to combat both hepatitis B and HIV infections. Acting through the inhibition of the reverse transcriptase enzyme, it can reduce viral load and limit replication within the patient's bloodstream. Synonyms: 5-(2-Amino-6-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-4-methyl-tetrahydro-furan-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyl-tetrahydrofuran-3-ol. CAS No. 881881-89-6. Molecular formula: C11H13ClFN5O3. Mole weight: 317.70. | |
| 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-trifluoromethyl-a-D-glucofuranose | 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-trifluoromethyl-α-D-glucofuranose is an intriguing biomedicine, exhibiting exceptional efficacy in the research of diabetes and various metabolic aberrations. With its remarkable capability to impede specific enzymes crucial in glucose metabolism, it facilitates the harmonization of blood glucose levels. Molecular formula: C13H19F3O5. Mole weight: 312.28. | |
| 3-Deoxy-3-fluoro-D-glucitol | 3-Deoxy-3-fluoro-D-glucitol, also known as FDG, is an immensely powerful antidiabetic drug that exhibits significant efficacy in managing type 2 diabetes mellitus. This remarkable medication operates through its ability to impede the glucokinase enzyme, culminating in a notable decline in blood glucose concentrations. Additionally, its intricate mechanism entails the augmentation of insulin sensitivity and facilitation of glucose utilization within the physiological framework. CAS No. 34339-82-7. Molecular formula: C6H13FO5. Mole weight: 184.16. | |
| 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase | This enzyme is the product of the Lewis blood group gene. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. Although it is a 4-fucosyltransferase, it has a persistent 3-fucosyltransferase activity towards the glucose residue in free lactose. This enzyme fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3, unlike EC 2.4.1.152, 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase, which fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4. Enzymes catalysing the 4-α-fucosylation of the GlcNAc in β-D-Gal-(1?3)-β-GlcNAc sequences (with some activity also as 3-α-fucosyltransferases) are present in plants, where the function in vivo is the modification of N-glycans. In addition, the fucTa gene of Helicobacter strain UA948 encodes a fucosyltransferase with both 3-α- and 4-α-fucosyltransferase activities. Group: Enzymes. Synonyms: (Lea)-dependent (α-3/4)-fucosyltransferase; α(1,3/1,4) fucosyltransferase III; α-(1?4)-L-fucosyltransferase; α-4-L-fucosyltransferase; β-acetylglucosaminylsaccharide fucosyltransferase; FucT-II; Lewis α-(1?3/4)-fucosyltransferase; Lewis blood group α-(1?3/4)-fucosyltransferase; Lewis(Le) blood . Enzyme Commi | |
| 3-Nitropropionic Acid | A cell-permeable, irreversible inactivator (~3mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme. Disrupts the blood-brain barrier and causes severe energy (ATP) impairment. Also replicates several pathophysiological symptoms of Huntington disease, including spontaneous choreiform and dystonic movements and degeneration of striatum in rodent models. Chronic administration of 3-NP (38mg/kg/day) is shown to cause activation of c-Jun kinase in striatum. Group: Biochemicals. Alternative Names: 3-NP, 3-NPA, 3NPA. Grades: Highly Purified. CAS No. 504-88-1. Pack Sizes: 50mg. Molecular Formula: C?H?NO?. US Biological Life Sciences. | Worldwide |
| 4-Nitrophenyl laurate | 4-Nitrophenyl laurate, a remarkable biomedicine with a captivating name, astounds the scientific realm by its stupendous potential in addressing cardiovascular afflictions, foremost among them being hypertension. Serving as an exceptionally vigorous inhibitor, this marvel counters the nefarious actions of angiotensin converting enzyme (ACE), an enzyme pivotal in the intricate orchestration of blood pressure control. Alas, its grandeur does not cease there! This exceptional compound, through its ACE inhibition, showcases the power to induce vasodilation and alleviate blood pressure concerns, a beacon of hope for individuals burdened by cardiovascular malaise. Synonyms: 4-Nitrophenyl dodecanoate. CAS No. 1956-11-2. Molecular formula: C18H27NO4. Mole weight: 321.41. | |
| 4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose | 4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose, a compound of utmost importance in the biomedical industry, has garnered significant attention due to its potential implications in the research of diabetes and associated metabolic ailments. Serving as an compound for reducing glucose levels, this compound adeptly modulates the regulation of blood sugar. Its unparalleled structure facilitates precise interactions with enzymes involved in glucose metabolism. Synonyms: Cellobiose thiol. Molecular formula: C12H22O10S. Mole weight: 358.36. | |
| 5-O-Methyl Quercetin | O-Methylated analogue of the flavanoid Quercertin. It is a small molecule inhibitor of NADPH Oxidase 4 enzyme. It is used in studies of flavonoid structure requirement for the increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4,7-Tetrahydroxy-5-methoxyflavone; Azaleatin; Quercetin 5-Methyl Ether. Grades: Highly Purified. CAS No. 529-51-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7H-Dibenzo[c,g]carbazole | 7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DBC. CAS No. 194-59-2. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-119983. |  |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565, an illuminating dye utilized extensively in biomedical research, binds to cGMP, a vital molecule that regulates different physiological processes like platelet aggregation, blood pressure regulation, and smooth muscle relaxation. Visualizing and scrutinizing the cGMP signaling in cells and tissues, measuring the activity of enzymes responsible for synthesizing or hydrolyzing cGMP, ATTO-565 caters to all of your specific experimental demands and unravels the answers locked deep within the biochemistry of the cell. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 565. Grades: ≥ 95% by HPLC. Molecular formula: C47H54N9O11P (free acid). Mole weight: 951.97 (free acid). | |
| Acarbose sulfate | Acarbose sulfate is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates. Acarbose sulfate decreased the Fasting Blood Glucose of DM Rats. The fasting blood glucose (FBG) in the acarbose-treated group decreased significantly at week 2 (P<0.05), week 4 (P<0.05), week 6 (P<0.05), and week 8 (P<0.05) compared to the DM group. Synonyms: Bay-g 5421 sulfate; BAY g 5421 sulfate. Grades:>98%. CAS No. 1221158-13-9. Molecular formula: C25H45NO22S. Mole weight: 743.68. | |
| Alanine Aminotransferase from Human, Recombinant | Alanine transaminase (ALT) is a transaminase enzyme. It is also called alanine aminotransferase (ALAT) and was formerly called serum glutamate-pyruvate transaminase (SGPT) or serum glutamic-pyruvic transaminase (SGPT). ALT is found in plasma and in various body tissues, but is most common in the liver. It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST (aspartate transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels. Alanine aminotransferase human recombinant produced in e. coli is a homodimer, nonglycosylated, polypeptide chain containing 495a.a...inotransferase; pyruvate transaminase; pyruvate-alanine aminotransferase; pyruvate-glutamate transaminase. CAS No. 9000-86-6. Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. ALT. Mole weight: 54,479 Da. Activity: 1,000 U/mg. Stability: AAT1 although stable at 10°C for 5 days, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile liquid formulation. Source: E. coli. Species: Human. ALT1; Glutamic-pyruvic transaminase 1; GPT 1; Glutamic-alanine transaminase 1; AAT1; ALT; ALAT; SGPT; Alanine transaminase; alanine aminotransferase; GPT; β-alanine aminotransferase; alanine-α | |
| Albumin | Albumin. CAS No. 9048-49-1. Product ID: PE-0600. Category: Stabilizer; Therapeutic Agents. Product Keywords: Other Materials; Stabilizers; PE-0600; Albumin; Stabilizer; Therapeutic Agents; ; 9048-49-1. Chemical Name: Serum albumin. Grade: Pharmceutical Excipients. Administration route: Intravenous. Dosage Form: Intravenous injection. Stability and Storage Conditions: Albumin is a protein and is therefore prone to chemical degradation and denaturation under extreme pH conditions, high salt concentrations, heat, enzymes, organic solvents and other chemical agents present. Albumin solution should be stored away from light at 2 ~ 25 ° C, or according to label instructions. Source and Preparation: Human blood albumin is a sterile, pyrogen free serum albumin product obtained from a healthy donor's isolate (source blood, plasma, serum or placenta); The source material must not be tested to contain hepatitis B surface antigen. The production process should ensure that the product is safe and can be used for intravenous injection. Applications: Albumin is mainly used as an excipient in the prescription of injectable drugs, as a stabilizer for proteins and enzymes in the prescription. Albumin is also used in the preparation of microspheres and microcapsules in experimental drug delivery systems. As a stabilizer, albumin is used in protein prescriptions at a low concentration of 0.003%. However, concentrations of 1.to 5% are usually |  |
| Alkaline Protease for detergent | Protease is a kind of enzyme preparation produced by one microbes submerged fermentation. It is also a kind of modified enzyme preparation after DNA recombination. As a common used enzyme preparation in detergent industry, the main activated composition alkaline protease can rapidly decompose protein. Protease can hydrolyze the hardly soluble protein on fabric into soluble peptide chain and amino acid in detergent solution. smoothness. Therefore, after the washing with cellulase, white clothes will be whiter and color clothes will be brighter and softer. At the same time, it can get off the granular dirt in the fiber. Applications: Protease can effectively remove sweat stain, blood stains, food protein dirt, cream stain and etc, the detergent contains protease will make fabric get perfect effect after washing. Group: Enzymes. Synonyms: Alkaline Protease; for detergent; Protease; decompose protein; Detergent Enzymes; Detergents; Alkaline Protease for detergent; DETE-2623. CAS No. 37259-58-8. Alkaline Protease. Appearance: powder or liquid. Alkaline Protease; for detergent; Protease; decompose protein; Detergent Enzymes; Detergents; Alkaline Protease for detergent; DETE-2623. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2623. | |
| α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant | A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.65. CAS No. 37277-69-3. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter mustelae. Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Cat No: NATE-1484. | |
| α-1,3-N-acetyl-galactosaminyltransferase from Helicobacter mustelae, Recombinant | In enzymology, a glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase (EC 2.4.1.40) is an enzyme that catalyzes the chemical reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose ? UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-[alpha-L-fucosyl- (1,2)]-D-galactose. Thus, the two substrates of this enzyme are UDP-N-acetyl-D-galactosamine and glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose, whereas its 3 products are UDP, [[glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-[alpha-L-fucosyl-]], and [[(1,2)]-D-galactose]]. Group: Enzymes. Synonyms: UDP-N-ace. Enzyme Commission Number: EC 2.4.1.40. CAS No. 9067-69-0. Purity: min 95% by SDS-PAGE. α-1,3-N-acetyl-galactosaminyltransferase. Mole weight: 37 kDa. Source: E. coli. Species: Helicobacter mustelae. UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-ga lactose 3-N-acetyl-D-galactosaminyltransferase; A-transferase; histo-blood group A glycosyltransferase; (Fucalpha1?2Galalpha1?3-N-acetylgalactosaminyltransferase); UDP-GalNAc:Fucalpha1?2Galalpha1?3-N-acetylgalactosaminyltransferase; alpha-3-N-acetylgalactosaminyltransferase; blood-group substance alpha-acetyltransferase; blood-group substance A-dependent acetylgalactosaminyltransferase; fucosylgalactose acetylga | |
| α-1,4-Galactosyltransferase from Neisseria meningitides, Recombinant | Lactosylceramide 4-alpha-galactosyltransferase is an enzyme that in humans is encoded by the A4GALT gene. The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Group: Enzymes. Synonyms: lactosylceramide 4-alpha-galactosyltransferase; Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-ga. Enzyme Commission Number: EC 2.4.1.228. CAS No. 52725-57-2. Purity: min 95% by SDS-PAGE. Galactosyltransferase. Mole weight: 34 kDa. Source: E. coli. Species: Neisseria meningitides. lactosylceramide 4-alpha-galactosyltransferase; Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase; UDP-galactose:beta-D-galactosyl-(1->4)-D-glucosyl(1<->1)ceramide 4II-alpha-D-galactosyltransferase; UDP-galactose:beta-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide 4II-alpha-D-galactosyltransferase; α-1,4-Galactosyltransferase. Cat No: NATE-1479. | |
| α-N-acetylgalactosaminidase | The human lysosomal enzyme is involved in the degradation of blood type A epitope. Group: Enzymes. Synonyms: α-acetylgalactosaminidase; N-acetyl-α-D-galactosaminidase; N-acetyl-α-galactosaminidase; α-NAGAL; α-NAGA; α-GalNAcase. Enzyme Commission Number: EC 3.2.1.49. CAS No. 9075-63-2. α-NAGA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3912; α-N-acetylgalactosaminidase; EC 3.2.1.49; 9075-63-2; α-acetylgalactosaminidase; N-acetyl-α-D-galactosaminidase; N-acetyl-α-galactosaminidase; α-NAGAL; α-NAGA; α-GalNAcase. Cat No: EXWM-3912. | |
| AM-643 | AM-643 is an active molecular. In the Biological Tests, it can inhibit FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA and the activity value is 0.081μM. It can also Inhibit COX1-mediated TXB2 production in human whole blood after 30 mins by competitive enzyme immunoassay and the activity value is 25μM. Synonyms: AM-643 Free Acid; AM643 Free Acid; UNII-55668SZQ3E;3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid. Grades: 98%. CAS No. 1233114-22-1. Molecular formula: C36H40N4O4S. Mole weight: 642.79. | |
| Angiotensin I (human, rat, mouse) trifluoroacetate salt | Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grades: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48. | |
| Animal Tissue PCR Kit | Animal Tissue PCR Kit. Animal tissue pcr kit uses a unique lysis buffer to lyse animal tissues (fresh or frozen) and blood. the resulting lysate without purification can be directly used as pcr template. pcr product can be directly used for gel electrophoresis. Group: Cloning Enzymes. Purity: 100×; 500×. Storage: Store at -20 ?. Cat No: CE-3011. | |
| Aspartate Transaminase (Crude Enzyme) | (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase(SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2. 6. 1. 1) that was first described by Arthur Karmen and colleagues in 1954. AST catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, and red blood cells. Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis; medicine; biotechnology. Group: Enzymes. Synonyms: glutamic-oxaloacetic transaminase; glutamic-aspartic transaminase; transaminase A; AAT; AspT; 2-oxoglutarate-glutamate aminotransferase; aspartate α-ketoglutarate transaminase; aspartate aminotransferase; aspartate-2-oxoglutarate transaminase; aspartic a. Enzyme Commission Number: EC 2.6.1.1. CAS No. 9000-97-9. AST. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. glutamic-oxaloacetic transamina | |
| Atorvastatin calcium hydrate | Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver. Uses: Scientific research. Group: Natural products. CAS No. 344423-98-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112490. | |
| Autotaxin Inhibitor III, PF-8380 (Atx Inhibitor III, PF-8380, 6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one) | An orally bioavailable piperazinyl benzoxazolone compound that acts as a substrate competitive and tight-binding inhibitor of autotaxin activity {IC50=2.8 and 1.7nM for recombinant human enzyme-b isoform employing FS-3 and LPC (lysophosphatidyl choline) as substrates, respectively; 1.16 and 1.15nM for rat/murine enzyme-FS-3 and fetal fibroblast cell-LPC; 101nM for human whole blood}. Displays desirable pharmacokinetics properties and efficiently blocks inflammation-induced LPA (lysophosphatidic acid) production both in plasma and at the site of inflammation by 95% in rat adjuvant-induced arthritis model (30mg/kg, p.o.).CAS No:1144035-53-9. Group: Biochemicals. Grades: Highly Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| AZ32 | AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with IC50 of <6.2 nM for ATM enzyme and IC50 of 0.31 μM for ATM in cell. AZ32 is tolerated in C57Bl6 and Nude mice dosed orally at 200mg/kg which was efficacious in orthotopic mouse models. AZ32 is the first ATMi with oral bioavailability shown to radiosensitize glioma and improve survival in orthotopic mouse models. It also shows adequate selectivity over ATR and also has high cell permeability. Synonyms: AZ-32; AZ 32; N-methyl-4-(6-phenylimidazo[1,2-a]pyrazin-3-yl)benzamide. Grades: ≥98%. CAS No. 2288709-96-4. Molecular formula: C20H16N4O. Mole weight: 328.37. | |
| AZD1390 | AZD1390 is a first-in-class, orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. It can be used to cross the blood-brain barrier suitable for the treatment of intracranial malignancies. Synonyms: AZD-1390; AZD 1390. Grades: ≥98%. CAS No. 2089288-03-7. Molecular formula: C27H32FN5O2. Mole weight: 477.57. | |
| BAY 56-3722 | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
| Benazepril | Benazepril, an angiotensin converting enzyme inhibitor, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. It is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor upon cleavage of its ester group by the liver. Synonyms: 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-; (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid; 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, [S-(R*,R*)]-; Benapril; Briem; Cibacen; Cibacen WS; Cibacene; 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grades: >98%. CAS No. 86541-75-5. Molecular formula: C24H28N2O5. Mole weight: 424.49. | |
| β-cyano-L-alanine | β-cyano-L-alanine is a reversible inhibitor of the H2S-synthesizing enzyme CSE. It blocks H2S synthesis in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. Synonyms: BCA; beta-cyano-L-alanine; 3-Cyano-L-alanine; L-3-Cyanoalanine. Grades: ≥ 98% (TLC). CAS No. 6232-19-5. Molecular formula: C4H6N2O2. Mole weight: 114.1. | |
| β-Galactose Dehydrogenase S from Pseudomonas fluorescens, Recombinant | In enzymology, a galactose 1-dehydrogenase (EC 1.1.1.48) is an enzyme that catalyzes the chemical reaction: D-galactose + NAD+ rightleftharpoons D-galactono-1,4-lactone + NADH + H+. Thus, the two substrates of this enzyme are D-galactose and NAD+, whereas its 3 products are D-galactono-1,4-lactone, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. This enzyme participates in galactose metabolism. Applications: Β-galactose dehydrogenase s has been used in the colorimetric microassay method to determine the level of galactose and galactose-1-phosphate in blood. Group: Enzymes. Synonyms: D-galactose:NAD+ 1-oxidoreductase; D-galactose dehydrogenase; beta-galactose dehydrogenase; NAD+-dependent D-galactose dehydrogenase; galactose 1-dehydrogenase; EC 1.. Enzyme Commission Number: EC 1.1.1.48. Galactose dehydrogenase. Activity: 80 U/mg protein. Storage: Store at -20°C. Form: Suspension in 3.2 M ammonium sulfate solution, pH approximately 6. Source: E. coli. Species: Pseudomonas fluorescens. D-galactose:NAD+ 1-oxidoreductase; D-galactose dehydrogenase; beta-galactose dehydrogenase; NAD+-dependent D-galactose dehydrogenase; galactose 1-dehydrogenase; EC 1.1.1.48; Galactose dehydrogenase. Cat No: NATE-1710. | |
| Bexarotene (4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid) | A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce AB40 and AB42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6h and 50% reduction in 72h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of AB proteases, insulin degrading enzyme, and neprilysin. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Bilirubin | Bilirubin (formerly referred to as haematoidin) is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the bodys clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin.Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such as stercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.It has also been found in plants. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cholerythrin. Product Category: Heterocyclic Organic Compound. Appearance: Solid. CAS No. 635-65-4. Molecular formula: C33H36N4O6. Mole weight: 584.66. Purity: 0.98. IUPACName: 3-[2-[[3-(2-Car |  |
| Blood-group endo-β-galactosidase 98A from Streptococcus pneumoniae, Recombinant | Blood-group-substance endo-1,4-beta-galactosidase (EC 3.2.1.102, endo-beta-galactosidase, blood-group-substance 1,4-beta-D-galactanohydrolase) is an enzyme with systematic name blood-group-substance 4-beta-D-galactanohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction: Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances. Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to a 1,3-alpha-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-alpha-D-fucosyl residue. Group: Enzymes. Synonyms: Blood-group-substance endo-1,4-beta-galactosidase; EC 3.2.1.102; endo-beta-galactosidase; blood-group-substance 1,4-beta-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.102. CAS No. 52720-51-1. Purity: >90% by SDS-PAGE. Endo-β-galactosidase. Mole weight: 69.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Streptococcus pneumoniae. Blood-group-substance endo-1,4-beta-galactosidase; EC 3.2.1.102; endo-beta-galactosidase; blood-group-substance 1,4-beta-D-galactanohydrolase; Blood-group endo-β-galactosidase 98A. Cat No: NATE-1411. | |
| blood-group-substance endo-1,4-β-galactosidase | Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to a 1,3-α-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-α-D-fucosyl residue. Group: Enzymes. Synonyms: endo-β-galactosidase (ambiguous); blood-group-substance 1,4-β-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.102. CAS No. 52720-51-1. Endo-β-galactosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3785; blood-group-substance endo-1,4-β-galactosidase; EC 3.2.1.102; 52720-51-1; endo-β-galactosidase (ambiguous); blood-group-substance 1,4-β-D-galactanohydrolase. Cat No: EXWM-3785. | |
| Blood PCR Kit | Blood PCR Kit. Blood pcr kit is designed for dna amplification from whole blood without dna extraction. Group: Cloning Enzymes. Purity: 100×; 500×. Storage: Store at -20 ?. Cat No: CE-3012. | |
| BW-B 70C | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
| Carbohydrase enzyme blend for Detergent | Carbohydrase enzyme blend preparation used in medical and surgical instrument cleaning detergents to remove carbohydrate-containing materials such as blood, food and feces. Applications: Instrument cleaning. Group: Enzymes. Synonyms: Carbohydrase enzyme; Medical; surgical instrument; cleaning detergents; remove carbohydrate-containing materials; Detergents; Carbohydrase enzyme blend for Medical; DETE-2632. Carbohydrase. Appearance: powder or liquid. Carbohydrase enzyme; Medical; surgical instrument; cleaning detergents; remove carbohydrate-containing materials; Detergents; Carbohydrase enzyme blend for Medical; DETE-2632. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2632. | |
| Carbonic Anhydrase II from Bovine, Recombinant | The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonic anhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Carbonic anhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. one of its main physiological roles is to maintain the acid-base balance in blood and other tissues. lack of carbonic anhydrase results in carbonic anhydrase type ii defi...ns: Carbonic anhydrase is used to create carbon dioxide capture systems and to research various purification techniques. carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type ii deficiency syndrome. bovine carbonic anhydrase ii (ca II), has been widely used as a model protein in the investigation of the protein folding process. Group: Enzymes. Synonyms: carbonic anhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. Purity: >90% by SDS-PAGE. Carbonic Anhydras | |
| Carmustine | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Synonyms: 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin. Grades: ≥98%. CAS No. 154-93-8. Molecular formula: C5H9Cl2N3O2. Mole weight: 214.05. | |
| CAY10606 | Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme that in humans is encoded by the ALOX5 gene. 5-LO initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 is a potent, reversible inhibitor of 5-LO, both in cell-free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-LO is activated with the calcium ionophore A23187 with IC50 of 1.6 μM. Synonyms: CAY 10606; CAY-10606. Grades: ≥98%. CAS No. 1159576-98-3. Molecular formula: C22H18ClNO3. Mole weight: 379.8. | |
| CAY10700 | Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. CAY10700 is a novel selective and orally bioavailable inhibitor of mPGES-1 with IC50 of 0.24 μM for human whole blood assay. Uses: Enzyme inhibitors. Synonyms: mPGES-1 Inhibitor-1; CAY 10700; CAY-10700. Grades: ≥98%. CAS No. 1381846-21-4. Molecular formula: C16H19ClN4O2. Mole weight: 334.8. | |
| Chemically modified Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides | Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction:D-glucose 6-phosphate + NADP+ <-> 6-phospho-D-glucono-1,5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). Applications: Use glucose-6-phosphate dehydrogenase for the determination of blood glucose or creatine kinase. Group: Enzymes. Synonyms: D-glucose 6-phosphate dehydrogenase; glucose 6-phosphate dehydrogenase (NADP); NADP-dependent glu. Glucose-6-phosphate dehydrogenase. Mole weight: 110 kD (2 identical subunits 55,000 D). Activity: >30 U/mg lyophilizate. Stability: At +2 to +8°C within specification range for 18 months. Store dry. Appearance: White lyophilizate. Source: E. coli. Species: Leuconostoc mesenteroides. EC 1.1.1.49; NADP-glucose-6-phosphate dehydrogenase; Zwischenferment; D-glucose 6-phosphate dehydrogenase; glucose 6-phosphate dehydrogenase (NADP); NADP-dependent glucose 6-phosphate dehydrogenase; 6-phosphoglucose dehydrogenase; Entner-Doudoroff enzyme; glucose-6-phosphate 1-dehydrogenase; G6PDH; GPD; glucose-6-phosphate dehydrogenase; 9001-40-5. Cat No: DIA-280. | |
| Chlorotrianisene | Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 569-57-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B2158. | |
| cholesterol 24-hydroxylase | A P-450 heme-thiolate protein. The enzyme can also produce 25-hydroxycholesterol. In addition, it can further hydroxylate the product to 24,25-dihydroxycholesterol and 24,27-dihydroxycholesterol. This reaction is the first step in the enzymic degradation of cholesterol in the brain as hydroxycholesterol can pass the blood-brain barrier whereas cholesterol cannot. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Enzyme Commission Number: EC 1.14.14.25. CAS No. 50812-30-1, 213327-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0922; cholesterol 24-hydroxylase; EC 1.14.14.25; 50812-30-1, 213327-78-7; cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Cat No: EXWM-0922. | |
| Chymotrypsin | Chymotrypsin is a proteolytic enzyme. It can priority hydrolyze tyrosine containing l-isomer, phenylalanine and the peptide bond of tryptophan, the best effective condition is pH 8.0. Its activity can be restrained by heavy metal or natural trypsin inhibitor in some degrees. Applications: Practically used to heal cicatrisation caused by injuries, inflammation and it is also used for avoiding part dropsy, blood-gathering, haematoma caused by wrick, breast dropsy after operation, tympanitis and rhinitis brief introduction of production: the high purity chymotrypsin is extracted from bovine or porcine pancreas and purified by affinity chromatography in order to avoid being polluted by other protease. Group: Enzymes. Synonyms: Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. CAS No. 9004-7-3. Chymotrypsin. Appearance: inquire. Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. Pack: inquire. Cat No: BIO-1012. | |
| coagulation factor IXa | A chymotrypsin homologue, and one of the γ-carboxyglutamic acid-containing blood coagulation factors. The proenzyme factor IX is activated by factor XIa. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: activated Christmas factor; blood-coagulation factor IXa; activated blood-coagulation factor IX; autoprothrombin II; blood platelet cofactor II; activated blood coagulation factor XI. Enzyme Commission Number: EC 3.4.21.22. CAS No. 37316-87-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4122; coagulation factor IXa; EC 3.4.21.22; 37316-87-3; activated Christmas factor; blood-coagulation factor IXa; activated blood-coagulation factor IX; autoprothrombin II; blood platelet cofactor II; activated blood coagulation factor XI. Cat No: EXWM-4122. | |
| coagulation factor VIIa | Formed from the precursor factor VII. The cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: blood-coagulation factor VIIa; activated blood coagulation factor VII. Enzyme Commission Number: EC 3.4.21.21. CAS No. 65312-43-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4121; coagulation factor VIIa; EC 3.4.21.21; 65312-43-8; blood-coagulation factor VIIa; activated blood coagulation factor VII. Cat No: EXWM-4121. | |
| coagulation factor Xa | A blood coagulation factor formed from the proenzyme factor X by limited proteolysis. Factor X is a glycoprotein composed of a heavy chain and a light chain, which are generated from a precursor protein by the excision of the tripeptide RKR and held together by one or more disulfide bonds. The activated factor Xa converts prothrombin to thrombin in the presence of factor Va, Ca2+ and phospholipids. Scutelarin (EC 3.4.21.60) has similar specificity, but does not require factor Va. Group: Enzymes. Synonyms: thrombokinase; prothrombase; prothrombinase; activated blood-coagulation factor X; autoprothrombin C; thromboplastin; plasma thromboplastin; factor Xa; activated Stuart-Prower factor; activated factor X. Enzyme Commission Number: EC 3.4.21.6. CAS No. 9002-5-5. Factor Xa. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4150; coagulation factor Xa; EC 3.4.21.6; 9002-05-5; thrombokinase; prothrombase; prothrombinase; activated blood-coagulation factor X; autoprothrombin C; thromboplastin; plasma thromboplastin; factor Xa; activated Stuart-Prower factor; activated factor X. Cat No: EXWM-4150. | |
| coagulation factor XIa | In peptidase family S1 (trypsin family), and one of the γ-carboxyglutamic acid-containing blood coagulation factors. The proenzyme factor XI is activated by factor XIIa. Group: Enzymes. Synonyms: blood-coagulation factor XIa; activated blood-coagulation factor XI; activated plasma thromboplastin antecedent. Enzyme Commission Number: EC 3.4.21.27. CAS No. 37203-61-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4125; coagulation factor XIa; EC 3.4.21.27; 37203-61-5; blood-coagulation factor XIa; activated blood-coagulation factor XI; activated plasma thromboplastin antecedent. Cat No: EXWM-4125. | |
| coagulation factor XIIa | Also activates plasminogen and plasma prokallikrein. Formed from the proenzyme, factor XII, by plasma kallikrein or factor XIIa. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: Hageman factor (activated); blood-coagulation factor XIIf; activated β blood-coagulation factor XII; prealbumin activator; Hageman factor β-fragment; Hageman factor fragment HFf; blood-coagulation factor XIIaβ; prekallikrein activator; kallikreinogen activator. Enzyme Commission Number: EC 3.4.21.38. CAS No. 75216-42-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4132; coagulation factor XIIa; EC 3.4.21.38; 75216-42-1; Hageman factor (activated); blood-coagulation factor XIIf; activated β blood-coagulation factor XII; prealbumin activator; Hageman factor β-fragment; Hageman factor fragment HFf; blood-coagulation factor XIIaβ; prekallikrein activator; kallikreinogen activator. Cat No: EXWM-4132. | |
| Concentrated alkaline protease for Medical | Concentrated, alkaline protease enzyme used in medical and surgical instrument cleaning products to remove protein-containing, organic materials such as blood, mucus, feces and foods. Applications: Laundry. Group: Enzymes. Synonyms: alkaline protease; Concentrated alkaline protease for Medical; alkaline protease enzyme; medical; surgical instrument ; cleaning; Detergents; Concentrated alkaline protease for Medical; DETE-2631. CAS No. 37259-58-8. Alkaline Protease. Appearance: powder or liquid. alkaline protease; Concentrated alkaline protease for Medical; alkaline protease enzyme; medical; surgical instrument ; cleaning; Detergents; Concentrated alkaline protease for Medical; DETE-2631. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2631. | |
| Concentrated neutral bacterial protease for detergent | Highly concentrated neutral bacterial protease enzyme used in laundry detergents and cleaning products to remove protein containing stains such as grass, blood, mucus, feces and foods. Applications: Protein stains. Group: Enzymes. Synonyms: Concentrated neutral bacterial protease; for detergent; concentrated neutral bacterial protease enzyme; laundry detergents; remove protein containing stains?Detergent Enzymes; bacterial protease; neutral protease; Detergents; Concentrated neutral bacterial protease for detergent; DETE-2626. CAS No. 37259-58-8. Neutral Protease. Appearance: powder or liquid. Source: Bacterial. Concentrated neutral bacterial protease; for detergent; concentrated neutral bacterial protease enzyme; laundry detergents; remove protein containing stains?Detergent Enzymes; bacterial protease; neutral protease; Detergents; Concentrated neutral bacterial protease for detergent; DETE-2626. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2626. | |
| Creatinase from Pseudomonas sp., Recombinant | In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction:creatine + H2O<-> sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. Creatinase accelerates the conversion reaction of creatine and water molecule to sarcosine and urea. It always acts in homodimer state and is induced by choline chloride. Recombinant, expressed in e. coli, lyophilized powder, 10-15 units/mg protein. Applications: Creatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine. Group: Enzymes. Synonyms: Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Creatinase. Activity: 10-20 units/mg protein. Stability: 2-8°C. Form: lyophilized powder. Source: E. coli. Species: Pseudomonas sp. Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Cat No: NATE-0162. | |
| Creatine Kinase MB Isoenzyme Type-2 from Human, Recombinant | CK-MB Type II possesses the naturally occurring carboxy-terminal amino acid lysine. This occurs during a myocardial infarct (MI or heart attack) when CK-MB Type II is released from damaged heart muscle, and the C-terminal lysine is cleaved in the blood stream, thus creating CK-MB Type I. This difference can be exploited in diagnosis of an MI. Ckmbitii human recombinant produced in pichia pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to mb isoenzyme in elisa. the ckmbitii is purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Creatine Kinase MB Isoenzyme Type-II; Creatine Kinase MB Isoenzyme Type-2; CKMBT2; CKMBITII; CKMBII; CKMB. Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. CK. Activity: 892 IU/mg. Stability: CKMBITII although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered colourless liquid formulation. Source: Pichia Pastoris. Species: Human. Creatine Kinase MB Isoenzyme Type-II; Creatine Kinase MB Isoenzyme Type-2; CKMBT2; CKMBITII; CKMBII; CKMB. Cat No: NATE-0819. | |
| Deserpidine | Deserpidine is an antihypertensive drug related to Reserpine. It is naturally found in Rauvolfia spp. Deserpidine is a competitive ACE (angiotensin converting enzyme) inhibitor. Deserpidine can block the conversion of angiotensin I to angiotensin II as a potent vasoconstrictor through competing with angiotensin I for ACE. Reduced level of serum angiotensin II leads to a decrease in blood pressure. Deserpidine can also decrease angiotensin II-induced aldosterone secretion by the adrenal cortex. Uses: Antihypertensive drug. Synonyms: (3β, 16β, 17α, 18β, 20α)-17-methoxy-18-[(3, 4, 5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester; Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate; Deserpidin; 1-Demethoxyreserpine; 11-Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine. Grades: 95%. CAS No. 131-01-1. Molecular formula: C32H38N2O8. Mole weight: 578.66. | |
| Dimethyl-l-arginine | Dimethyl-l-arginine is naturally found in blood plasma. It is produced from the continual protein modification processes in the cytoplasm of all human cells. Uses: Enzyme inhibitors. Synonyms: N,N-dimethylarginine; ADMA; Asymmetric dimethylarginine; NG,NG-dimethyl-L-arginine. Grades: >98%. CAS No. 30315-93-6. Molecular formula: C8H18N4O2. Mole weight: 202.258. | |
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