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Product | Description | |
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1,5,6,7-Tetra-O-benzylvoglibose Quick inquiry Where to buy Suppliers range | 1,5,6,7-Tetra-O-benzylvoglibose, a carbohydrate-derived substance employed in the field of biomedicine, has been exhaustively researched due to its potential as an anti-diabetic medication in the fight against type 2 diabetes. This compound is ingeniously engineered to obstruct alpha-glucosidase enzymes, which play a critical role in carbohydrate digestion. Its ability to curtail postprandial blood glucose levels is a promising therapeutic choice in the management of type 2 diabetes. Synonyms: TBV. CAS No. 115250-39-0. Molecular formula: C38H45NO7. Mole weight: 627.77. | |
1,5-Anhydro-4,6-O-benzylidene-2-O-toluoyl-D-glucitol Quick inquiry Where to buy Suppliers range | 1,5-Anhydro-4,6-O-benzylidene-2-O-toluoyl-D-glucitol, a chemical compound praised for its antidiabetic properties, is typically utilized as a key ingredient in the development of groundbreaking medications. This compound facilitates effective glucose management by selectively targeting alpha-glucosidase enzymes, an important regulatory mechanism for optimal blood sugar levels in the body of patients afflicted with diabetes. CAS No. 156715-23-0. Molecular formula: C21H22O6. Mole weight: 370.4. | |
1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-toluoyl-D-glucitol Quick inquiry Where to buy Suppliers range | 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-toluoyl-D-glucitol, widely recognized as a pivotal compound within the biomedical realm, assumes a significant role in the treatment of diverse ailments, foremost among them being diabetes. Its unparalleled capability to regulate blood sugar levels renders it an indispensable entity. This invaluable product seamlessly inhibits α-glucosidase enzymes, thereby facilitating enhanced glycemic control. Synonyms: 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-2-O-(4-methylbenzoyl)-D-ribo-hexitol. CAS No. 149312-19-6. Molecular formula: C21H22O5. Mole weight: 354.4. | |
1,5-Anhydro-4,6-O-benzylidene-3-O-[2,4-dichlorophenyl]thiocarbonyloxy-2-O-toluoyl-D-glucitol Quick inquiry Where to buy Suppliers range | 1,5-Anhydro-4,6-O-benzylidene-3-O-[2,4-dichlorophenyl]thiocarbonyloxy-2-O-toluoyl-D-glucitol, a novel compound, has shown potent inhibition of alpha-glucosidase enzymes, making it a promising candidate for diabetes therapy. By reducing carbohydrate absorption, it is expected to effectively lower blood glucose levels. Its potential as a therapeutic agent for type 2 diabetes warrants further investigation, given its unique chemical profile and mechanism of action. Molecular formula: C28H24Cl2O7S. Mole weight: 575.46. | |
1-Chloro-1-deoxy-scyllo-inositol Quick inquiry Where to buy Suppliers range | 1-Chloro-1-deoxy-scyllo-inositol, a promising therapeutic candidate for the treatment of metabolic conditions like obesity and diabetes, exerts its action by suppressing the enzymatic activity of α-glucosidase, the key enzyme involved in the hydrolysis of carbohydrates into glucose, which subsequently limits the intestinal absorption of glucose, ultimately resulting in a reduced blood glucose level. Molecular formula: C6H11ClO5. Mole weight: 198.60. | |
1-Deoxy-D-sorbose Quick inquiry Where to buy Suppliers range | 1-Deoxy-D-sorbose, a remarkable biomedical substance, presents itself as a promising therapeutic tool in the management of diabetes. By means of obstructing the action of aldose reductase, a pivotal enzyme implicated in diabetic complications, this compound adeptly modulates blood glucose levels. Synonyms: methylxylose. Molecular formula: C6H12O5. Mole weight: 164.16. | |
1-Deoxy-L-talitol Quick inquiry Where to buy Suppliers range | 1-Deoxy-L-talitol is a biomedical compound utilized in the treatment of various diseases. This product acts as an inhibitor and has shown promising effects in treating metabolic disorders and diabetes. By suppressing specific enzyme activities, it regulates glucose metabolism, ultimately aiding in controlling blood glucose levels. Its potential therapeutic benefits make 1-Deoxy-L-talitol an essential component in the biomedicine industry. Molecular formula: C6H14O5. Mole weight: 166.17. | |
2,2,2-trifluoroethyl formate Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 12 (2,2,2-trifluoroethyl formate) is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: Lisinopril Impurity 12. Grades: 97 % (HPLC). CAS No. 32042-38-9. Molecular formula: C3H3F3O2. Mole weight: 128.05. | |
2-((5-Chloropyridin-2-yl)amino)-2-oxoacetic Acid Quick inquiry Where to buy Suppliers range | 2-((5-Chloropyridin-2-yl)amino)-2-oxoacetic Acid is a reactant or reagent used in the synthesis of the blood coagulating enzyme factor Xa (FXa) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 552850-73-4. Pack Sizes: 1g, 5g. Molecular Formula: C7H5ClN2O3, Molecular Weight: 200.58. US Biological Life Sciences. | Worldwide |
2-Acetamido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol Quick inquiry Where to buy Suppliers range | 2-Acetamido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol, a synthetically derived organic compound, serves as a potent inhibitor of glucosidase enzymes in the biomedical sector. In clinical settings, this molecule aids in regulating excessive blood glucose levels in type 2 diabetes patients, in addition to mitigating symptoms of various metabolic disorders. The multifunctional nature of this compound has demonstrated its potential in expanding therapeutic avenues. Molecular formula: C20H28N2O6. Mole weight: 392.45. | |
2-Acetamido-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol Quick inquiry Where to buy Suppliers range | 2-Acetamido-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol is a synthetic compound used in the biomedical industry for treating type 2 diabetes. It works by inhibiting alpha-glucosidase, an enzyme that breaks down carbohydrates in the small intestine, slowing down the absorption of glucose and reducing blood sugar level. Synonyms: 2-ACETAMIDO-4,6-O-BENZYLIDENE-N-(TERT-BUTOXYCARBONYL)-1,2,5-TRIDEOXY-1,5-IMINO-D-GLUCITOL; tert-butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydro-[1,3]dioxino[5,4-b]pyridine-5-carboxylate; tert-Butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenylhexahydro-5H-[1,3]dioxino[5,4-b]pyridine-5-carboxylate; starbld0032901; DTXSID00565023; tert-Butyl (4aR,7S,8R,8aR)-7-acetamido-8-hydroxy-2-phenylhexahydro-2H,5H-[1,3]dioxino[5,4-b]pyridine-5-carboxylate. CAS No. 1221795-90-9. Molecular formula: C20H28N2O6. Mole weight: 392.45. | |
2-Amino-2-deoxy-glucitol Quick inquiry Where to buy Suppliers range | 2-Amino-2-deoxy-glucitol, also known as miglitol, is a pharmacological agent used in the management of hyperglycemia associated with type 2 diabetes mellitus. Its mechanism of action involves the inhibition of alpha-glucosidase enzymes responsible for the breakdown of carbohydrates in the small intestine. This leads to a delay in the absorption of glucose, resulting in lower postprandial blood glucose levels. Despite its efficacy, miglitol may cause gastrointestinal side effects such as flatulence and diarrhea and is best used in combination with other antidiabetic agents. Synonyms: 5-aminohexane-1,2,3,4,6-pentol; 2351-14-6; SCHEMBL3797037; DTXSID60313360; NSC269409; NSC-269409. CAS No. 2351-14-6. Molecular formula: C6H15NO5. Mole weight: 181.19. | |
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol Quick inquiry Where to buy Suppliers range | (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol is an incredibly potent antiviral compound, employed to combat both hepatitis B and HIV infections. Acting through the inhibition of the reverse transcriptase enzyme, it can reduce viral load and limit replication within the patient's bloodstream. Synonyms: 5-(2-Amino-6-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-4-methyl-tetrahydro-furan-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyl-tetrahydrofuran-3-ol. CAS No. 881881-89-6. Molecular formula: C11H13ClFN5O3. Mole weight: 317.70. | |
3-Deoxy-1,2:5,6-di-O-isopropylidene-3-trifluoromethyl-a-D-glucofuranose Quick inquiry Where to buy Suppliers range | 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-trifluoromethyl-α-D-glucofuranose is an intriguing biomedicine, exhibiting exceptional efficacy in the research of diabetes and various metabolic aberrations. With its remarkable capability to impede specific enzymes crucial in glucose metabolism, it facilitates the harmonization of blood glucose levels. Molecular formula: C13H19F3O5. Mole weight: 312.28. | |
3-Deoxy-3-fluoro-D-glucitol Quick inquiry Where to buy Suppliers range | 3-Deoxy-3-fluoro-D-glucitol, also known as FDG, is an immensely powerful antidiabetic drug that exhibits significant efficacy in managing type 2 diabetes mellitus. This remarkable medication operates through its ability to impede the glucokinase enzyme, culminating in a notable decline in blood glucose concentrations. Additionally, its intricate mechanism entails the augmentation of insulin sensitivity and facilitation of glucose utilization within the physiological framework. CAS No. 34339-82-7. Molecular formula: C6H13FO5. Mole weight: 184.16. | |
3-Nitropropionic Acid Quick inquiry Where to buy Suppliers range | A cell-permeable, irreversible inactivator (~3mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme. Disrupts the blood-brain barrier and causes severe energy (ATP) impairment. Also replicates several pathophysiological symptoms of Huntington disease, including spontaneous choreiform and dystonic movements and degeneration of striatum in rodent models. Chronic administration of 3-NP (38mg/kg/day) is shown to cause activation of c-Jun kinase in striatum. Group: Biochemicals. Alternative Names: 3-NP, 3-NPA, 3NPA. Grades: Highly Purified. CAS No. 504-88-1. Pack Sizes: 50mg. Molecular Formula: C?H?NO?. US Biological Life Sciences. | Worldwide |
4-Nitrophenyl laurate Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl laurate, a remarkable biomedicine with a captivating name, astounds the scientific realm by its stupendous potential in addressing cardiovascular afflictions, foremost among them being hypertension. Serving as an exceptionally vigorous inhibitor, this marvel counters the nefarious actions of angiotensin converting enzyme (ACE), an enzyme pivotal in the intricate orchestration of blood pressure control. Alas, its grandeur does not cease there! This exceptional compound, through its ACE inhibition, showcases the power to induce vasodilation and alleviate blood pressure concerns, a beacon of hope for individuals burdened by cardiovascular malaise. Synonyms: 4-Nitrophenyl dodecanoate. CAS No. 1956-11-2. Molecular formula: C18H27NO4. Mole weight: 321.41. | |
4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose Quick inquiry Where to buy Suppliers range | 4-O-(b-D-Glucopyranosyl)-b-D-thioglucopyranose, a compound of utmost importance in the biomedical industry, has garnered significant attention due to its potential implications in the research of diabetes and associated metabolic ailments. Serving as an compound for reducing glucose levels, this compound adeptly modulates the regulation of blood sugar. Its unparalleled structure facilitates precise interactions with enzymes involved in glucose metabolism. Synonyms: Cellobiose thiol. Molecular formula: C12H22O10S. Mole weight: 358.36. | |
5-O-Methyl Quercetin Quick inquiry Where to buy Suppliers range | O-Methylated analogue of the flavanoid Quercertin. It is a small molecule inhibitor of NADPH Oxidase 4 enzyme. It is used in studies of flavonoid structure requirement for the increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4,7-Tetrahydroxy-5-methoxyflavone; Azaleatin; Quercetin 5-Methyl Ether. Grades: Highly Purified. CAS No. 529-51-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565 Quick inquiry Where to buy Suppliers range | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565, an illuminating dye utilized extensively in biomedical research, binds to cGMP, a vital molecule that regulates different physiological processes like platelet aggregation, blood pressure regulation, and smooth muscle relaxation. Visualizing and scrutinizing the cGMP signaling in cells and tissues, measuring the activity of enzymes responsible for synthesizing or hydrolyzing cGMP, ATTO-565 caters to all of your specific experimental demands and unravels the answers locked deep within the biochemistry of the cell. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 565. Grades: ≥ 95% by HPLC. Molecular formula: C47H54N9O11P (free acid). Mole weight: 951.97 (free acid). | |
Acarbose sulfate Quick inquiry Where to buy Suppliers range | Acarbose sulfate is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates. Acarbose sulfate decreased the Fasting Blood Glucose of DM Rats. The fasting blood glucose (FBG) in the acarbose-treated group decreased significantly at week 2 (P<0.05), week 4 (P<0.05), week 6 (P<0.05), and week 8 (P<0.05) compared to the DM group. Synonyms: Bay-g 5421 sulfate; BAY g 5421 sulfate. Grades:>98%. CAS No. 1221158-13-9. Molecular formula: C25H45NO22S. Mole weight: 743.68. | |
Acetylcysteine Ph. Eur. Quick inquiry Where to buy Suppliers range | Acetylcysteine is also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC. It is the N-acetyl derivative of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase 1) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores. Acetylcysteine can also be used as a general antioxidant which can help mitigate symptoms for a variety of diseases exacerbated by reactive oxygen species (ROS). Uses: API. CAS No. 616-91-1. Product ID: 10-101-106. | |
AM-643 Quick inquiry Where to buy Suppliers range | AM-643 is an active molecular. In the Biological Tests, it can inhibit FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA and the activity value is 0.081μM. It can also Inhibit COX1-mediated TXB2 production in human whole blood after 30 mins by competitive enzyme immunoassay and the activity value is 25μM. Synonyms: AM-643 Free Acid; AM643 Free Acid; UNII-55668SZQ3E;3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid. Grades: 98%. CAS No. 1233114-22-1. Molecular formula: C36H40N4O4S. Mole weight: 642.79. | |
Angiotensin I (human, rat, mouse) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grades: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48. | |
Aprotinin Quick inquiry Where to buy Suppliers range | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. Synonyms: H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH; EC: 3.4.21.9; Iniprol; Trasylol; Trazinin; Zymofren; Riker 52G. Grades: >99%. CAS No. 9087-70-1. Molecular formula: C284H432N84O79S7. Mole weight: 6511.48. | |
AS1940477 Quick inquiry Where to buy Suppliers range | AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent concentrations of AS1940477 that inhibited cytokine production also inhibited TNFα- and IL-1 β-induced production of IL-6, PGE(2), and MMP-3 in human synovial stromal cells. AS1940477 was also found to potently inhibit TNF production in whole blood (IC(50)=12 nM) and effectively inhibited TNFα production induced by systemically administered LPS in rats at less than 0.1mg/kg (ED(50)=0.053 mg/kg) with an anti-inflammatory effect lasting for 20h after oral administration. Overall, this study demonstrated that AS1940477 is a novel and potent p38 MAPK inhibitor and may be useful as a promising anti-inflammatory agent for treating inflammatory disorders. Synonyms: AS1940477; AS-1940477; AS 1940477. CAS No. 928344-12-1. Molecular formula: C24H22FN5O2. Mole weight: 431.47. | |
Autotaxin Inhibitor III, PF-8380 (Atx Inhibitor III, PF-8380, 6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one) Quick inquiry Where to buy Suppliers range | An orally bioavailable piperazinyl benzoxazolone compound that acts as a substrate competitive and tight-binding inhibitor of autotaxin activity {IC50=2.8 and 1.7nM for recombinant human enzyme-b isoform employing FS-3 and LPC (lysophosphatidyl choline) as substrates, respectively; 1.16 and 1.15nM for rat/murine enzyme-FS-3 and fetal fibroblast cell-LPC; 101nM for human whole blood}. Displays desirable pharmacokinetics properties and efficiently blocks inflammation-induced LPA (lysophosphatidic acid) production both in plasma and at the site of inflammation by 95% in rat adjuvant-induced arthritis model (30mg/kg, p.o.).CAS No:1144035-53-9. Group: Biochemicals. Grades: Highly Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
AZ32 Quick inquiry Where to buy Suppliers range | AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with IC50 of <6.2 nM for ATM enzyme and IC50 of 0.31 μM for ATM in cell. AZ32 is tolerated in C57Bl6 and Nude mice dosed orally at 200mg/kg which was efficacious in orthotopic mouse models. AZ32 is the first ATMi with oral bioavailability shown to radiosensitize glioma and improve survival in orthotopic mouse models. It also shows adequate selectivity over ATR and also has high cell permeability. Synonyms: AZ-32; AZ 32; N-methyl-4-(6-phenylimidazo[1,2-a]pyrazin-3-yl)benzamide. Grades: ≥98%. CAS No. 2288709-96-4. Molecular formula: C20H16N4O. Mole weight: 328.37. | |
AZD1390 Quick inquiry Where to buy Suppliers range | AZD1390 is a first-in-class, orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. It can be used to cross the blood-brain barrier suitable for the treatment of intracranial malignancies. Synonyms: AZD-1390; AZD 1390. Grades: ≥98%. CAS No. 2089288-03-7. Molecular formula: C27H32FN5O2. Mole weight: 477.57. | |
BAY 56-3722 Quick inquiry Where to buy Suppliers range | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
Benazepril Quick inquiry Where to buy Suppliers range | Benazepril, an angiotensin converting enzyme inhibitor, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. It is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor upon cleavage of its ester group by the liver. Synonyms: 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-; (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid; 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, [S-(R*,R*)]-; Benapril; Briem; Cibacen; Cibacen WS; Cibacene; 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grades: >98%. CAS No. 86541-75-5. Molecular formula: C24H28N2O5. Mole weight: 424.49. | |
β-cyano-L-alanine Quick inquiry Where to buy Suppliers range | β-cyano-L-alanine is a reversible inhibitor of the H2S-synthesizing enzyme CSE. It blocks H2S synthesis in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. Synonyms: BCA; beta-cyano-L-alanine; 3-Cyano-L-alanine; L-3-Cyanoalanine. Grades: ≥ 98% (TLC). CAS No. 6232-19-5. Molecular formula: C4H6N2O2. Mole weight: 114.1. | |
Bexarotene (4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid) Quick inquiry Where to buy Suppliers range | A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce AB40 and AB42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6h and 50% reduction in 72h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of AB proteases, insulin degrading enzyme, and neprilysin. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Bromelain Quick inquiry Where to buy Suppliers range | Bromelain is a protein-digesting enzyme extracted from the stem, fruit, and juice of the pineapple plant (Ananas comosus). It belongs to a group of enzymes called proteases or proteinases. Bromelain is a complex mixture of enzymes that can hydrolyze (break down) various types of proteins, including collagen, elastin, and fibrin. Uses: 1. Anti-inflammatory: Bromelain has been found to possess anti-inflammatory properties, which makes it useful in the treatment of arthritis, asthma, allergies, and other conditions characterized by inflammation. 2. Digestive aid: Bromelain is often used as a digestive aid because it helps break down proteins in the digestive tract, aiding digestion and reducing bloating. 3. Wound healing: Bromelain has been found to help reduce inflammation and promote healing, making it useful in the treatment of burns, injuries, and surgical wounds. 4. Cancer treatment: Bromelain has been suggested to have anti-cancer properties, with studies showing that it may help inhibit the growth of cancer cells. 5. Cardiovascular health: Bromelain has been found to have blood-thinning and cholesterol-lowering properties, which makes it useful in reducing the risk of heart disease. 6. Skin care: Bromelain is sometimes used as an ingredient in skin care products because of its ability to gently exfoliate the skin and help remove dead skin cells. 7. Sinusitis treatment: Because of its anti-inflammatory properties, bromelain has been found to be helpful in reducing nasal swelling and inflammation in people with sinusitis. Group: Skin Actives. Alternative Names: STEM BROMELAIN; 3.4.22.32; BROMELAIN; BROMELAIN PINEAPPLE;BROMELIN;EC 3.4.22.1;EC 3.4.22.32;EC 3.4.22.4. CAS No. 9001-00-7. Product ID: ACM9001007. Molecular formula: N/A. Mole weight: N/A. Appearance: yellow to beige crystalline powder. | |
BW-B 70C Quick inquiry Where to buy Suppliers range | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
Carmustine Quick inquiry Where to buy Suppliers range | Carmustine is antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. It is used in the treatment of brain tumors, multiple myeloma and some lymphomas. Synonyms: 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin. Grades: ≥98%. CAS No. 154-93-8. Molecular formula: C5H9Cl2N3O2. Mole weight: 214.05. | |
CAY10606 Quick inquiry Where to buy Suppliers range | Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme that in humans is encoded by the ALOX5 gene. 5-LO initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 is a potent, reversible inhibitor of 5-LO, both in cell-free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-LO is activated with the calcium ionophore A23187 with IC50 of 1.6 μM. Synonyms: CAY 10606; CAY-10606. Grades: ≥98%. CAS No. 1159576-98-3. Molecular formula: C22H18ClNO3. Mole weight: 379.8. | |
CAY10700 Quick inquiry Where to buy Suppliers range | Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. CAY10700 is a novel selective and orally bioavailable inhibitor of mPGES-1 with IC50 of 0.24 μM for human whole blood assay. Uses: Enzyme inhibitors. Synonyms: mPGES-1 Inhibitor-1; CAY 10700; CAY-10700. Grades: ≥98%. CAS No. 1381846-21-4. Molecular formula: C16H19ClN4O2. Mole weight: 334.8. | |
Deserpidine Quick inquiry Where to buy Suppliers range | Deserpidine is an antihypertensive drug related to Reserpine. It is naturally found in Rauvolfia spp. Deserpidine is a competitive ACE (angiotensin converting enzyme) inhibitor. Deserpidine can block the conversion of angiotensin I to angiotensin II as a potent vasoconstrictor through competing with angiotensin I for ACE. Reduced level of serum angiotensin II leads to a decrease in blood pressure. Deserpidine can also decrease angiotensin II-induced aldosterone secretion by the adrenal cortex. Uses: Antihypertensive drug. Synonyms: (3β, 16β, 17α, 18β, 20α)-17-methoxy-18-[(3, 4, 5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester; Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate; Deserpidin; 1-Demethoxyreserpine; 11-Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine. Grades: 95%. CAS No. 131-01-1. Molecular formula: C32H38N2O8. Mole weight: 578.66. | |
D-Glucose-1-12C (13C depleted at C1) Quick inquiry Where to buy Suppliers range | Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a significant role in photosynthesis and energy source required for cellular respiration. D-Glucose is used in various metabolic processes including the synthesis of enzymic cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in type 2 diabetes mellitus detection and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus. Molecular formula: [12]CC5H12O6. Mole weight: 180.15. | |
D-Glucose-1-13C Quick inquiry Where to buy Suppliers range | Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus. Group: Biochemicals. Alternative Names: 1-13C-Glucose; D-[1-13C]Glucose; Glucose-1-13C; [1-13C]-D-Glucose; [1-13C]D-Glucose. Grades: Highly Purified. CAS No. 40762-22-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
D-Glucose-1,6-diphosphate potassium salt Quick inquiry Where to buy Suppliers range | D-Glucose-1,6-diphosphate potassium salt, a crucial biomedical agent, holds immense potential in addressing glucose-6-phosphate dehydrogenase (G6PD) deficiency and associated enzymopathies. Its primary function revolves around intricately regulating glucose metabolism while augmenting the vitality of red blood cells. CAS No. 32972-45-5. Molecular formula: C6H10K4O12P2. Mole weight: 492.48. | |
D-Glucose-2-12C (13C depleted at C2) Quick inquiry Where to buy Suppliers range | Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a significant role in photosynthesis and energy source required for cellular respiration. D-Glucose is used in various metabolic processes including the synthesis of enzymic cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in type 2 diabetes mellitus detection and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus. Molecular formula: [12]CC5H12O6. Mole weight: 180.15. | |
D-Glucose-d12 Quick inquiry Where to buy Suppliers range | Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntingtons disease through analysis of blood-glucose in type 1 diabetes mellitus. Group: Biochemicals. Alternative Names: D-[2H12]Glucose; D-[UL-2H12]Glucose. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C6D12O6, Molecular Weight: 192.23. US Biological Life Sciences. | Worldwide |
Dimethyl-l-arginine Quick inquiry Where to buy Suppliers range | Dimethyl-l-arginine is naturally found in blood plasma. It is produced from the continual protein modification processes in the cytoplasm of all human cells. Uses: Enzyme inhibitors. Synonyms: N,N-dimethylarginine; ADMA; Asymmetric dimethylarginine; NG,NG-dimethyl-L-arginine. Grades: >98%. CAS No. 30315-93-6. Molecular formula: C8H18N4O2. Mole weight: 202.258. | |
Enalapril Quick inquiry Where to buy Suppliers range | Enalapril is an angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. Its IC50 values range from 2 to 800 nM. lt belongs to a class of medications called angiotensin converting enzyme inhibitors. pressure. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt has been shown to lower the death rate in systolic heart failure. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Uses: Enalapril is used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. lt decreases levels of angiotensin ii leading to less vasoconstriction and decreased blood pressure by inhibiting ace. lt lowers the death rate in systolic heart failure. Synonyms: (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid. Grades: 98 %. CAS No. 75847-73-3. Molecular formula: C20H28N2O5. Mole weight: 376.45. | |
Enalkiren Quick inquiry Where to buy Suppliers range | Enalkiren: Introducing Enalkiren is an efficacious and exclusive suppressor of human renin, a pivotal enzyme within the renin-angiotensin-aldosterone system. Its indispensable role lies in studying hypertension (increased blood pressure) and congestive heart failure. Uses: Protease inhibitors. Synonyms: Enalquireno; Enalkirene; 3-amino-N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-3-methylbutanamide. CAS No. 113082-98-7. Molecular formula: C35H56N6O6. Mole weight: 656.86. | |
Enzastaurin Quick inquiry Where to buy Suppliers range | Enzastaurin is a protein kinase C beta inhibitor with 6- to 20-fold selectivity against PKCα, PKCγ and PKC&epsilon. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Synonyms: 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615. CAS No. 170364-57-5. Molecular formula: C32H29N5O2. Mole weight: 515.617. | |
Etoposide, 95.0-105.0% (HPLC) USP Quick inquiry Where to buy Suppliers range | Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcrip- tion and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells. Group: Biochemicals. Alternative Names: 4-Des methyl epipodophyllotoxin; VP-16-213, NSC 141540. Grades: USP. CAS No. 33419-42-0. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
Fosinoprilat acyl-b-D-glucuronide Quick inquiry Where to buy Suppliers range | Fosinoprilat acyl-b-D-glucuronide, an esteemed biomedical compound, stands as a valuable solution for individuals grappling with hypertension and heart failure. This pharmacological entity acts as an active metabolite of Fosinopril, showcasing its prowess as an angiotensin-converting enzyme inhibitor. By judiciously impeding the angiotensin-converting enzyme's activity and dwindling the generation of angiotensin II, Fosinoprilat acyl-b-D-glucuronide splendidly fosters vasodilation and effectively curtails blood pressure. Synonyms: trans-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline b-D-glucopyranuronosyl ester. CAS No. 113411-09-9. Molecular formula: C29H42NO11P. Mole weight: 611.62. | |
GIRK Activator, ML297 (1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea, N-(3,4-Difluorophenyl)-N?-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea, CID 56642816, VU0456810) Quick inquiry Where to buy Suppliers range | A blood-brain barrier-permeable, non-toxic phenyl-pyrazolylurea compound that acts as a direct, potent, fast, and reversible activator of GIRK1 (G-protein activated inward-rectifying K+ channel containing subunit 1) containing channels (EC50 = 162, 914, and 887nM in Thallium influx assay for GIRK1/2, GIRK1/3, and GIRK1/4 expressed in HEK-293 cell lines). Its action does not require the presence of an activated Gi GPCR. Shown to be inactive towards GIRK2, GIRK2/3, Kir2.1, KV7.4 and GABAA, and weakly active against a panel of 61 other receptors, ion channels, enzymes, transporters, and proteins even at higher concentration (~10uM). Exhibits desirable pharmacokinetic properties with good solubility (17.5uM), predicted hepatic clearance (88 ml/min/kg), and Tmax of 640nM and 130nM in plasma and brain, respectively. Shown to reduce locomotor function and seizure frequency in electroshock- and chemically-induced murine epilepsy models (60mg/kg, i.p). Group: Biochemicals. Grades: Highly Purified. CAS No. 1443246-62-5. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O. US Biological Life Sciences. | Worldwide |
GPI-15427 Quick inquiry Where to buy Suppliers range | GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment in the management of HNSCC. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: GPI 15427; GPI15427; 10-((4-Methylpiperazin-1-yl)methyl)chromeno(4,3,2-de)phthalazin-3(2H)-one. CAS No. 805242-85-7. Molecular formula: C20H20N4O2. Mole weight: 348.41. | |
GSK2656157 Quick inquiry Where to buy Suppliers range | GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC50 of 0.9 nM. It is highly selective for PERK with IC50 values >100 nM against a panel of 300 kinases. GSK2656157 inhibits PERK activity in cells with an IC50 in the range of 10-30 nM as shown by inhibition of stress-induced PERK autophosphorylation, eIF2α substrate phosphorylation, together with corresponding decreases in ATF4 and CHOP proteins in multiple cell lines. Oral administration of GSK2656157 to mice shows a dose- and time-dependent pharmacodynamic response in pancreas as measured by PERK auto-phosphorylation. Twice daily dosing of GSK2656157 results in dose dependent inhibition of multiple human tumor xenografts growth in mice. Altered amino acid metabolism, decreased blood vessel density and vascular perfusion are potential mechanisms for the observed anti-tumor effect. However, despite its anti-tumor activity, given the on-target pharmacological effects of PERK inhibition on pancreatic function, development of any PERK inhibitor in human subjects would need to be cautiously pursued in cancer patients. Synonyms: GSK2656157; GSK 2656157; GSK-2656157. Grades: 0.98. CAS No. 1337532-29-2. Molecular formula: C23H21FN6O. Mole weight: 416.46. | |
Isopropyl 4-[4-[N,N-bis(2-hydroxyethyl)amino]phenyl]butyrate Quick inquiry Where to buy Suppliers range | Isopropyl 4-[4-[N,N-bis(2-hydroxyethyl)amino]phenyl]butyrate, a pharmaceutical intermediate, can be utilized in the production of drugs intended for the treatment of cardiovascular disease, such as hypertension. It functions as an angiotensin-converting enzyme (ACE) inhibitor, which reduces the likelihood of heart attack and stroke by regulating blood pressure levels. Consequently, it plays a valuable role in managing these serious medical conditions, thus improving overall health outcomes among patients. Synonyms: Isopropyl 4-(4-(bis(2-hydroxyethyl)amino)phenyl)butanoate. CAS No. 94086-78-9. Molecular formula: C17H27NO4. Mole weight: 309.40. | |
Isosaccharinic acid-1,4-lactone Quick inquiry Where to buy Suppliers range | Isosaccharinic acid-1,4-lactone, a molecule with significant pharmacological value, exhibits therapeutic efficacy against metabolic disorders. This biological agent detains the catabolism of intricate carbohydrates through the inhibition of specific enzymes, thereby preventing an abrupt escalation in blood glucose levels. Notably, Isosaccharinic acid-1,4-lactone also elicits potent anti-inflammatory activity, signifying its therapeutic potential in diverse inflammatory conditions. Synonyms: Isosaccharino-1,4-lactone; 7397-89-9; Isosaccharinic acid-1,4-lactone; (3S,5S)-3-hydroxy-3,5-bis(hydroxymethyl)oxolan-2-one; 20261-94-3; alpha-D-Isosaccharino-1,4-lactone; alpha-D-Isosaccharin; Isosaccharinicacid-1,4-lactone; SCHEMBL7150499; DTXSID40224708; Beta-D-isosaccharino-1,4-lactone; 3-Deoxy-2-C-(hydroxymethyl)-D-erythro-pentonic acid gamma-lactone; MFCD18252312; 3-deoxy-2-C-hydroxymethyl-D,L-tetrono-1,4-lactone; (3S,5S)-3-Hydroxy-3,5-bis-hydroxymethyl-dihydro-furan-2-one; (3S,5S)-3-hydroxy-3,5-bis(hydroxymethyl)tetrahydrofuran-2-one; D-erythro-Pentonic acid, 3-deoxy-2-C-(hydroxymethyl)-, gamma-lactone. CAS No. 7397-89-9. Molecular formula: C6H10O5. Mole weight: 162.14. | |
Lactosylsphingosine Quick inquiry Where to buy Suppliers range | Lactosylsphingosine, a sphingolipid, is a vital biomarker characterizing diverse lysosomal storage disorders such as Niemann-Pick disease and Gaucher disease due to its accumulation within the tissues and blood of affected people. Detection through blood examination or imaging studies makes identification possible. Therapy options include substrate reduction and enzyme replacement therapy. Furthermore, tracking variations in lactosylsphingosine may be employed to monitor therapy response and trace disease advancement, imparting substantial clinical value in disease management. Synonyms: D-lactosyl-beta1-1'-D-erythro-sphingosine; Lactosyl(beta) Sphingosine (d18:1); 2S,3R1-beta-lactosyl-sphing-4-enine; lyso-Lactosylceramide; 1-b-Lactosyl-sphing-4-enine; lyso-LC. Grades: >99%. CAS No. 109785-20-8. Molecular formula: C30H57NO12. Mole weight: 623.77. | |
L-Allono-1,4-lactone Quick inquiry Where to buy Suppliers range | L-Allono-1,4-lactone is a compound used in the research of diabetes by regulating blood glucose levels. It functions as an inhibitor of alpha-glucosidase enzyme, thus reducing carbohydrate breakdown and delaying sugar absorption. Synonyms: L-Allono-1,4-lactone; (3S,4R,5S)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one; (3S,4R,5S)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one; L-Allonic acid, gamma-lactone; DTXSID401318806. CAS No. 78184-43-7. Molecular formula: C6H10O6. Mole weight: 178.14. | |
L-α-Aspartyl-D-phenylalanine methyl ester Quick inquiry Where to buy Suppliers range | L-α-Aspartyl-D-phenylalanine methyl ester, a dipeptide compound, bears promise in the biomedical sector for its potential inhibitory impact on angiotensin converting enzyme (ACE), thus potentially reducing blood pressure levels. It has also shown potential in the treatment of hypertensive, cardiac failure, and other cardiovascular conditions. The study of its properties continues to generate interest and attention from academia and the scientific community. Synonyms: L-alpha-Aspartyl-D-phenylalanine methyl ester. CAS No. 22839-65-2. Molecular formula: C14H18N2O5. Mole weight: 294.3. | |
Lanreotide Quick inquiry Where to buy Suppliers range | Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Synonyms: Angiopeptin; Autogel; BIM 23014; DC 13-116; Dermopeptin; Ipstyl; L-Autogel; Lanreotide Autogel; Somatulin; Somatulin-Autogel; Somatuline Depot; L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2?7)-disulfide; H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2; 3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grades: 98%. CAS No. 108736-35-2. Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. | |
Lisinopril Quick inquiry Where to buy Suppliers range | Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Lisinopril is used primarily in treatment of high blood pressure, heart failure, and after heart attacks. it is also used for preventing kidney and eye complications in people with diabetes. it is used to improve survival in certain individuals following myocardial infarction, and to prevent progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy. Synonyms: (s)-1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-proline; lysinopril; mk0521; mk-0521; mk522; PRINIL; PRINIVIL; n-{n-[(s)-1-carboxy-3-phenylpropyl]-l-lysyl}-l-proline. Grades: > 95%. CAS No. 76547-98-3. Molecular formula: C21H31N3O5. Mole weight: 405.49. | |
Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Uses: Lisinopril impurity. Synonyms: (2S)-2-[(3S,8aRS)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-phenylbutanoic Acid. Grades: 96%. CAS No. 1092813-99-4. Molecular formula: C21H29N3O4. Mole weight: 387.47. | |
Lisinopril EP Impurity C HCl Quick inquiry Where to buy Suppliers range | Lisinopril EP Impurity C HCl ((S,S,S)-Diketopiperazine HCl) is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: (S,S,S)-Diketopiperazine HCl; (S)-2-((3S,8aS)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid, hydrochloride (1:1). Molecular formula: C21H29N3O4.HCl. Mole weight: 423.93. | |
Lisinopril EP Impurity D HCl Quick inquiry Where to buy Suppliers range | Lisinopril EP Impurity D HCl ((R,S,S)-Diketopiperazine HCl) is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: (R,S,S)-Diketopiperazine HCl. Molecular formula: C21H29N3O4.HCl. Mole weight: 423.93. | |
Lisinopril EP Impurity I Quick inquiry Where to buy Suppliers range | Lisinopril EP Impurity I is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Grades: > 95%. Molecular formula: C31H41N3O7. Mole weight: 567.67. | |
Lisinopril Impurity 10 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 10 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Molecular formula: C42H60N6O9. Mole weight: 792.96. | |
Lisinopril Impurity 14 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 14 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. CAS No. 329-53-3. Molecular formula: C10H12F6N2O4. Mole weight: 338.20. | |
Lisinopril Impurity 15 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 15 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: L-Lysine, N2-(2,2,2-trifluoroacetyl)-; trifluoroacetyl-L-lysine; trifluoroacetyl-lysine; n-trifluoroacetyllysine; N-trifluoroacetyl L-lysine; N-trifluoroacetyl-L-lysine; SCHEMBL287360; DTXSID101293299; CCG-233201; N2-(2,2,2-Trifluoroacetyl)-L-lysine; EN300-7034155; (2S)-6-amino-2-(trifluoroacetamido)hexanoic acid; BRD-K54317024-001-01-8. CAS No. 21761-08-0. Molecular formula: C8H13F3N2O3. Mole weight: 242.20. | |
Lisinopril Impurity 16 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 16 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Molecular formula: C20H25F3N2O6. Mole weight: 446.42. | |
Lisinopril Impurity 17 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 17 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Molecular formula: C20H25F3N2O6. Mole weight: 446.42. | |
Lisinopril Impurity 18 Quick inquiry Where to buy Suppliers range | Lisinopril Impurity 18 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Uses: Lisinopryl intermediate. Synonyms: N2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-N6-(2,2,2-trifluoroacetyl)-L-lysine. Grades: 95%. CAS No. 116169-90-5. Molecular formula: C20H27F3N2O5. Mole weight: 432.43. |