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| Product | Description | |
|---|---|---|
| EP2 | EP2 belongs to the antibacterial vermipeptide family (AVPF). It has antimicrobial activity. The source of EP2 is Eisenia fetida. Molecular formula: C26H43N5O10S. Mole weight: 617.71. |  |
| EP2B protein | EP2B is an antimicrobial protein produced by Macaca mulatta. | |
| Prostaglandin EP2 Receptor Antagonist, TG6-10-1 ( (E) -N- (2- (2- (trifluoromethyl) -1H-indol-1-yl) ethyl) -3- (3, 4, 5-trimethoxyphenyl) acrylamide, EP2 Antagonist, TG6-10-1) | A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb = 17.8nM). Exhibits about 300-fold selectivity for the EP2 receptor over human EP3, EP4, and IP receptors, about 100- fold selectivity over human EP1, 25-fold selectivity against human FP and TP, and 10-fold selectivity against human DP1 receptors. Does not affect the activity of about 40 enzymes, ion channels, receptors, and neurotransmitters even at higher concentrations (10uM). Shown to significantly reduce the induction of several inflammatory cytokines and chemokines and reduces the opening of blood-brain barrier during neuronal inflammation. Displays good pharmacokinetic properties with a half-life of 1.6 h and brain to plasma ratio of 1.6 in a murine model (5mg/kg i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. |  Worldwide |
| TPA_exp: EP2E protein | TPA_exp: EP2E protein is an antimicrobial peptide isolated from Sus scrofa. Synonyms: Arg-Asp-Val-Ile-Cys-Leu-Met-Gln-His-Gly-Thr-Cys-Arg-Leu-Phe-Phe-Cys-His-Ser-Gly-Glu-Lys-Lys-Ser-Glu-Ile-Cys-Ser-Asp-Pro-Trp-Asn-Arg-Cys-Cys. | |
| 11-deoxy-16,16-dimethyl prostaglandin E2 | AY 24609 is an analogue of PGE2 and a selective EP2 and EP3 receptors agonist. It also inhibits gastric acid secretion and ulcer formation in rat. Synonyms: AY 24609; 11-deoxy-16,16-dimethyl PGE2; (Z)-7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 53658-98-3. Molecular formula: C22H36O4. Mole weight: 364.5. | |
| 11-Deoxy prostaglandin E1 | 11-Deoxy prostaglandin E1 is a synthetic analog of PGE1. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively. Uses: Anti-ulcer agents. Synonyms: 11-deoxy PGE1; 7-[(1R,2R)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid. Grades: ≥96%. CAS No. 37786-00-8. Molecular formula: C20H34O4. Mole weight: 338.5. | |
| 1,2,3,4-Tetrahydroquinoline | 1,2,3,4-Tetrahydroquinoline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 51970-EP2286811A1; benzopiperidine; 1,2,3,4-Hydroquinoline; 15618-EP2316837A1; BBL027602; NCGC00188132-01; CHEBI:213323; 1,2,3,4 tetrahydroquinoline; TRA0087230; CJ-28881. Product Category: Quinolines. CAS No. 635-46-1. Molecular formula: C9H11N. Mole weight: 133.194g/mol. IUPACName: 1,2,3,4-tetrahydroquinoline. Canonical SMILES: C1CC2=CC=CC=C2NC1. ECNumber: 211-237-6. Product ID: ACM635461. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 15-keto-Prostaglandin E2 | 15-keto-Prostaglandin E2 is an endogenous metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to its Cys259 residue. 15-keto-Prostaglandin E2 can bind and stabilize EP2 and EP4 receptor. 15-keto-Prostaglandin E2 inhibits breast cancer cell growth and progression. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 15-keto-PGE2. CAS No. 26441-05-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113205. |  |
| 16,16-Dimethyl prostaglandin E2 | 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 16,16-dimethyl PGE2. CAS No. 39746-25-3. Pack Sizes: 5 mg (26.28 mM * 500 μL in Methyl acetate); 10 mg (26.28 mM * 1 mL in Methyl acetate); 25 mg (26.28 mM * 2.5 mL in Methyl acetate); 50 mg (26.28 mM * 5 mL in Methyl acetate); 100 mg (26.28 mM * 10 mL in Methyl acetate). Product ID: HY-106420. | |
| 19(R)-Hydroxy prostaglandin E2 | 19(R)-Hydroxy-prostaglandin E2 is a PGE2 metabolite that acts as a potent smooth muscle relaxant and a selective EP2 receptor agonist, contrary to PGE2, which can activate a variety of prostanoid receptor types. Synonyms: 19(R)-hydroxy PGE2; 19(R)-OH PGE2; 19(R)-hydroxy Prostaglandin E2. Grades: ≥98%. CAS No. 64625-54-3. Molecular formula: C20H32O6. Mole weight: 368.5. | |
| 19(R)-Hydroxy-prostaglandin E2 | 19(R)-hydroxy Prostaglandin E2 is a selective EP2 receptor agonist and a smooth muscle relaxant (1,2). Group: Biochemicals. Grades: Highly Purified. CAS No. 64625-54-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O6, Molecular Weight: 368.46. US Biological Life Sciences. | Worldwide |
| 2-[[2-(2-Ethylbutoxy)-2,2-diphenylacetyl]-methylamino]ethyl-dimethylazanium chloride | 2-[[2-(2-Ethylbutoxy)-2,2-diphenylacetyl]-methylamino]ethyl-dimethylazanium chloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: X-100, Acetamide, N-(2-(dimethylamino)ethyl)-2,2-diphenyl-2-(2-ethylbutoxy)-N-methyl-, hydrochloride, alpha-(2-Aethylbutoxy)benzilsaeure-(N,N,N-trimethylaethylen)amid hydrochlorid [German], N-(2-(Dimethylamino)ethyl)-2,2-diphenyl-2-(2-ethylbutoxy)-N-methylacetamide hydrochloride, AC1L2DJX, LS-9301, 199214-EP2270505A1, 2-[[2-(2-ethylbutoxy)-2,2-diphenylacetyl]-methylamino]ethyl-dimethylazanium chloride, alpha-(2-Aethylbutoxy)benzilsaeure-(N,N,N-trimethylaethylen)amid hydrochlorid, 3579-66-6. Product Category: Heterocyclic Organic Compound. CAS No. 3579-66-6. Molecular formula: C25H37ClN2O2. Mole weight: 433.026 g/mol. Purity: 0.96. IUPACName: 2-[[2-(2-ethylbutoxy)-2,2-diphenylacetyl]-methylamino]ethyl-dimethylazanium;chloride. Canonical SMILES: CCC(CC)COC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)N(C)CC[NH+](C)C.[Cl-]. Product ID: ACM3579666. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl | 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl. Uses: Ligand used in the pd-catalyzed suzuki coupling and animation of unactivated aryl chlorides. the reactions generally occur at room temperature and give high yields of product. ligand used in pd-catalyzed c-n bond formation. a general synthesis of n6-aryl-2'deoxyadenosine analogues. ligand used in pd-catalyzed n-arylation of indoles. ligand used in pd-catalyzed synthesis of aryl-tert-butyl ether. Additional or Alternative Names: 2-di-cyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl; 118492-EP2272832A1; (2'-dicyclohexylphosphanyl-biphenyl-2-yl)dimethyl-amine; 2-(Dicyclohexylphosphino)-2'-(N,N-diMethylaMino)biphenyl, 98% DavePhos; (2'-dicyclohexylphosphanyl -biphenyl-2-yl)-dimethyl-amine; Buchwald phosphine ligands, davephos phosphine ligand-; 2-dicyclohexylphosphino-2'-(N,N'-dimethylamino)biphenyl; [1,1'-BIPHENYL]-2-AMIN. Product Category: Organic Phosphine Compounds. CAS No. 213697-53-1. Molecular formula: C26H36NP. Mole weight: 393.555g/mol. IUPACName: 2-(2-dicyclohexylphosphanylphenyl)-N,N-dimethylaniline. Canonical SMILES: CN(C)C1=CC=CC=C1C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4. Product ID: ACM213697531. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-(Dimethylamino)-ethanethioamide | 2-(Dimethylamino)-ethanethioamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(dimethylamino)ethanethioamide, AC1MHUT2, AC1Q3WM3, STOCK6S-80934, CTK0J2565, MolPort-002-507-838, Ethanethioamide, 2-(dimethylamino)-, STK801440, ZINC54965167, AKOS000176021, AG-A-32479, MCULE-3863789639, EN300-33606, 204455-EP2277867A2, 204455-EP2280003A2, 27507-28-4. Product Category: Heterocyclic Organic Compound. CAS No. 27507-28-4. Molecular formula: C4H10N2S. Mole weight: 118.200600 [g/mol]. Purity: 0.96. IUPACName: 2-(dimethylamino)ethanethioamide. Canonical SMILES: CN(C)CC(=S)N. Product ID: ACM27507284. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2- (Trifluoromethoxy) ethanamine Hydrochloride | 2- (Trifluoromethoxy) ethanamine Hydrochloride was used in preparation of 2H-indazoles as EP2 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 886050-51-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C3H6F3NO; HCl, Molecular Weight: 129.083645999999. US Biological Life Sciences. | Worldwide |
| (3,5-Bis(trifluoromethyl)phenyl)boronic acid | (3,5-Bis(trifluoromethyl)phenyl)boronic acid. Uses: Suzuki reaction. Group: Salt. Alternative Names: CB-110; 3,5-Bis-trifluoromethylphenylboronic acid; (3,5-Bis(trifluoromethyl)phenyl)boronic acid; ST2414244; SCHEMBL126169; AKOS000285053; Boronic acid, [3,5-bis(trifluoromethyl)phenyl]-; 133412-EP2295406A1; ZINC169743211; 3,5-di(trifluoromethyl)-phenylboronic acid. CAS No. 73852-19-4. Product ID: [3,5-bis(trifluoromethyl)phenyl]boronic acid. Molecular formula: 257.926g/mol. Mole weight: C8H5BF6O2. B (C1=CC (=CC (=C1)C (F) (F)F)C (F) (F)F) (O)O. InChI=1S/C8H5BF6O2/c10-7(11, 12)4-1-5(8(13, 14)15)3-6(2-4)9(16)17/h1-3, 16-17H. BPTABBGLHGBJQR-UHFFFAOYSA-N. |  |
| (3,5-Dichloro-4-pyridyl)methanol | (3,5-Dichloro-4-pyridyl)methanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3,5-DICHLOROPYRIDIN-4-YL)METHANOL, SureCN321133, AGN-PC-01MK9N, 4-Pyridinemethanol, 3,5-dichloro-, AKOS006291938, (3,5-Dichloro-pyridin-4-yl)-methanol, FT-0683865, 91589-EP2305668A1, I01-9930, 159783-46-7. Product Category: Heterocyclic Organic Compound. CAS No. 159783-46-7. Molecular formula: C6H5Cl2NO. Mole weight: 178.02. Purity: 0.96. IUPACName: (3,5-dichloropyridin-4-yl)methanol. Canonical SMILES: C1=C(C(=C(C=N1)Cl)CO)Cl. Product ID: ACM159783467. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3-Buten-1-ol | 3-Buten-1-ol is an aliphatic primary alcohol used as a reagent in organic synthesis. Uses: 3-buten-1-ol is an aliphatic primary alcohol used as a reagent in organic synthesis. Additional or Alternative Names: 4-Hydroxy-1-butene; V6966; 79116-EP2305698A2; PubChem18909; UNII-3DB2KRM1I9; 3-Buten-1-O1; 627-27-0; ZINC1530356; KSC353Q2N; NSC60194. Product Category: Alkenes. Appearance: Clear colorless liquid. CAS No. 627-27-0. Molecular formula: C4H8O. Mole weight: 72.107g/mol. IUPACName: but-3-en-1-ol. Canonical SMILES: C=CCCO. Density: 0.838. ECNumber: 210-991-3. Product ID: ACM627270. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4,7-Diphenyl-1,10-phenanthroline, 98.5% | 4,7-Diphenyl-1,10-phenanthroline, 98.5%. Uses: Bidentate ligand and reagent for determination of iron. ligand used in the copper-catalyzed protodecarboxylation of aromatic carboxylic acids. Additional or Alternative Names: 4,7-Diphenyl-1,10-phenanthroline, nickel complex, tetrafluoroborate; DHDHJYNTEFLIHY-UHFFFAOYSA-N; CHEBI:77995; Bathophenanthroline, 99%; D0905; RTR-007169; CS-6274; SCHEMBL28868; 92129-EP2275395A2; CCRIS 9382. Product Category: Solution-Processed OLED. CAS No. 1662-01-7. Molecular formula: C24H16N2. Mole weight: 332.406g/mol. IUPACName: 4,7-diphenyl-1,10-phenanthroline. Canonical SMILES: C1=CC=C(C=C1)C2=C3C=CC4=C(C=CN=C4C3=NC=C2)C5=CC=CC=C5. ECNumber: 216-767-1. Product ID: ACM1662017. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Chlorobenzenecarboperoxoic acid | 4-Chlorobenzenecarboperoxoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-chlorobenzenecarboperoxoic acid, 4-chloroperbenzoic acid, 937-22-4, p-Chloroperbenzoic acid, AC1L2DS7, AC1Q68NP, CTK5H2859, EINECS 213-324-4, AR-1G1773, AG-K-79061, 72366-EP2308867A2, 72366-EP2308870A2. Product Category: Heterocyclic Organic Compound. CAS No. 937-22-4. Molecular formula: C7H5ClO3. Mole weight: 172.566 g/mol. Purity: 0.96. IUPACName: 4-chlorobenzenecarboperoxoic acid. Canonical SMILES: C1=CC(=CC=C1C(=O)OO)Cl. Density: 1.434g/cm³. ECNumber: 213-324-4. Product ID: ACM937224. Alfa Chemistry ISO 9001:2015 Certified. | |
| 6-Methoxy-4-pyrimidinamine | 6-Methoxy-4-pyrimidinamine is used in the synthesis of carbamothiolacrylamide s as selective EP2 antagonists in the treatment of neurodegenerative peripheral diseases. Also used in the preparation of PARP-1 inhibitors. Group: Biochemicals. Alternative Names: 4-Amino-6-methoxy-pyrimidine, ; 4-Amino-6-methoxypyrimidine; 6-Methoxy-4-aminopyrimidine; 6-Methoxy-4-pyrimidinamine. Grades: Highly Purified. CAS No. 696-45-7. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| (9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(diphenylphosphine) | (9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(diphenylphosphine). Uses: Ligand used for the hydroformylation of alkenes. ligand used in the intermolecular coupling of amides and hydrazones with aryl halides. ligand used in the intermolecular coupling of amides with aryl halides or triflates. ligand used in the coupling of heteroarylamines and aryl halides. ligand used in the hydrophosphinylation of alkenes and alkynes. ligand used for the au(I)-catalyzed dehydrog. Additional or Alternative Names: TRA0068476; Xanthene, 4,5-bis(diphenylphosphino)-9,9-dimethyl-; 4,5-bis(diphenylphosphino)-9,9-dimethlxanthene; FT-0645040; 9,9-dimethyl-4,5-bis(diphenylphosphino)-9H-xanthene; BP-12287; 30244-EP2280001A1; Y-200029; KSC485M5J; 9,9-dimethyl-4,5-bis(diphenyl phosphino)xanthene. Product Category: Organic Phosphine Compounds. CAS No. 161265-03-8. Molecular formula: C39H32OP2. Mole weight: 578.632g/mol. IUPACName: (5-diphenylphosphanyl-9,9-dimethylxanthen-4-yl)-diphenylphosphane. Canonical SMILES: CC1(C2=C(C(=CC=C2)P(C3=CC=CC=C3)C4=CC=CC=C4)OC5=C1C=CC=C5P(C6=CC=CC=C6)C7=CC=CC=C7)C. Product ID: ACM161265038. Alfa Chemistry ISO 9001:2015 Certified. | |
| AH 6809 | AH 6809 is an EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptor antagonist. Uses: An ep and dp receptor antagonist with nearly equal affinity for the cloned human ep1, ep2, ep3-iii, and dp1 receptors. Synonyms: AH 6809; AH6809; AH-6809; 6-isopropoxy-9-oxoxanthene-2-carboxylic acid. Grades: ≥95.0%. CAS No. 33458-93-4. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| Benzenesulfonamide,2-methoxy-(9ci) | Benzenesulfonamide,2-methoxy-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-methoxybenzenesulfonamide, 2-methoxy-Benzenesulfonamide, 2-methoxybenzene-1-sulfonamide, 52960-57-3, AC1NHF7E, SureCN529620, Benzenesulfonamide,N-methoxy-, CTK4H7984, MolPort-000-874-471, SBB070298, ZINC08496450, AKOS002664838, AG-K-81295, AG-L-63492, MCULE-4239739719, KB-85930, KB-116572, FT-0656240, EN300-86101, 79334-EP2305695A2. Product Category: Heterocyclic Organic Compound. CAS No. 52960-57-3. Molecular formula: C7H9NO3S. Mole weight: 187.21626. Purity: 0.96. IUPACName: 2-methoxybenzenesulfonamide. Canonical SMILES: COC1=CC=CC=C1S(=O)(=O)N. Density: 1.314g/cm³. Product ID: ACM52960573. Alfa Chemistry ISO 9001:2015 Certified. | |
| Benzoic acid,2-ethoxy-4-nitro- | Benzoic acid,2-ethoxy-4-nitro-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Ethoxy-4-nitrobenzoic acid, 2486-66-0, 2-ethoxy-4-nitro-benzoic Acid, ACMC-20anwx, AC1MC5DU, SureCN97838, 2-Ethoxy-4-nitrobenzoicacid, 549576_ALDRICH, Benzoic acid,2-ethoxy-4-nitro-, CTK4F4528, MolPort-001-769-149, OR5746, AKOS009158792, AKOS015889413, AG-E-74692, MCULE-5631577359, KB-94194, FT-0634316, X8074, 44280-EP2305250A1. Product Category: Heterocyclic Organic Compound. CAS No. 2486-66-0. Molecular formula: C9H9 N O5. Mole weight: 211.17. Purity: 0.96. IUPACName: 2-ethoxy-4-nitrobenzoic acid. Canonical SMILES: CCOC1=C(C=CC(=C1)[N+](=O)[O-])C(=O)O. Density: 1.368g/cm³. Product ID: ACM2486660. Alfa Chemistry ISO 9001:2015 Certified. | |
| Boc-(4-aminomethyl) benzoic acid | Boc-(4-aminomethyl) benzoic acid (CAS# 33233-67-9) is the Boc protected form of 4-(Aminomethyl)benzoic Acid (A615230) and is used as a reagent in the synthesis of indoleamide derivatives as EP2 antagonists with high selectivity. 4-(Boc-aminomethyl)benzoic Acid is also used as a reagent in the synthesis of aminopyridine-derived amides as nicotinamide phosphoribosyltransferase inhibitors. Synonyms: Boc-4-Amb-OH; 4-(Boc-aminomethyl)benzoic acid; 4-[(tert-Butoxycarbonylamino)methyl]benzoic acid. Grades: ≥ 98 % (HPLC). CAS No. 33233-67-9. Molecular formula: C13H17NO4. Mole weight: 251.27. | |
| Butaprost | Butaprost is a structural analog of PGE2 and a selective agonist for the EP2 receptor subtype. It binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor. Butaprost does not bind appreciably to any of the other murine EP receptors. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1; 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1. Grades: ≥95%. CAS No. 433219-55-7. Molecular formula: C23H38O5. Mole weight: 394.6. | |
| BW A868C | Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grades: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6. | |
| Carbonochloridic acid,2,2-dimethylpropyl ester | Carbonochloridic acid,2,2-dimethylpropyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Neopentyl chloroformate, 2,2-Dimethylpropyl chloroformate, 20412-38-8, ACMC-20ak51, AC1MNG08, AC1Q1MJ0, 460931_ALDRICH, CTK4E4155, 2,2-dimethylpropyl carbonochloridate, AKOS015912472, AG-E-49617, Carbonochloridic acid,2,2-dimethylpropyl ester, 143978-EP2287165A2, 143978-EP2287166A2, 143978-EP2292620A2, I14-47897, Formicacid, chloro-, neopentyl ester (6CI,8CI);1-Propanol, 2,2-dimethyl-,chloroformate (8CI);2,2-Dimethylpropyl chloroformate;Chloroformic acidneopentyl ester;Neopentyl chloroformate. Product Category: Heterocyclic Organic Compound. CAS No. 20412-38-8. Molecular formula: C6H11ClO2. Mole weight: 150.6. Purity: 0.96. IUPACName: 2,2-dimethylpropyl carbonochloridate. Canonical SMILES: CC(C)(C)COC(=O)Cl. Density: 1.003 g/mL at 25ºC(lit.). Product ID: ACM20412388. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cyclopropaneboronic acid | Cyclopropylboronic Acid is an organoboronic acid commonly used in highly efficient Suzuki coupling reactions. Synonyms: B-Cyclopropylboronic Acid; ACMC-1AMNO; Cyclopropyl Boronic Acid; Boronic Acid, Cyclopropyl- (9Ci); Cyclopropylboronic acid; cyclopropylboranediol; DTXSID00375402; QCR-242; ACN-S003927; 37410-EP2301922A1. Grades: > 98 % (GC). CAS No. 411235-57-9. Molecular formula: C3H7BO2. Mole weight: 85.9. | |
| DP2 Antagonist I (CRTH2 Antagonist I, GPR44 Antagonist I, (4-Chloro-2- ( (2-methyl-5- (propylsulfonyl) phenyl) ethynyl) phenoxy) acetic Acid) | A cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 2.0 and 2.4nM against 1.5nM PGD2 for human & murine DP2 binding, respectively), exhibiting much reduced potency against DP1 (Ki = 1.58uM; IC50 = 10uM), PGE receptor EP2 (54% inhibition at 10uM), and little or no activity toward 49 other receptors and ion channels. Effectively inhibits PGD2-induced cellular activation (IC50 = 32 and 80nM, respectively, using CHO-CRTH2 or human whole blood) in vitro and is efficacious in alleviating airway eosinophil infiltration in OVA-sensitized mice (30mg/kg; p.o.) in vivo with good oral bioavailability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??ClO?S. US Biological Life Sciences. | Worldwide |
| Eosin Y disodium salt, dye content 85%, indicator | Eosin Y disodium salt, dye content 85%, indicator. Uses: Anti septic. Group: Xanthene dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Product ID: disodium; 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Molecular formula: 691.859g/mol. Mole weight: C20H6Br4Na2O5. C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. InChI=1S/C20H8Br4O5. 2Na/c21-11-5-9-13 (7-3-1-2-4-8 (7)20 (27)28)10-6-12 (22)17 (26)15 (24)19 (10)29-18 (9)14 (23)16 (11)25; ; /h1-6, 25H, (H, 27, 28); ; /q; 2*+1/p-2. SEACYXSIPDVVMV-UHFFFAOYSA-L. | |
| EP4 receptor agonist 2 | EP4 receptor agonist 2 (compound 31) a potent EP4 receptor agonist with an EC 50 value of 0.8 nM; K i values of >100000, 38000, 3.1 nM for EP2, EP3, EP4 respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 493035-81-7. Pack Sizes: 1 mg (21.28 mM * 100 μL in Ethanol). Product ID: HY-118609. | |
| Ethyl Caproate | Ethyl Caproate is used in the synthesis of novel EP2/EP4 dual agonist of γ-lactam prostaglandin E1 analogs. Also used as a chemical reagent in the synthesis of PPARα antagonists in the treatment of metabolic diseases. Group: Biochemicals. Alternative Names: Hexanoic Acid Ethyl Ester; Caproic Acid Ethyl Ester; Ethyl Caproate; Ethyl Capronate; Ethyl Hexanoate; NSC 8882. Grades: Highly Purified. CAS No. 123-66-0. Pack Sizes: 5ml, 10ml, 25ml, 50ml. Molecular Formula: C?H??O?, Molecular Weight: 144.21. US Biological Life Sciences. | Worldwide |
| Glycylglycine (Gly-Gly, Diglycine) | N-Glycylglycine is a derivative of Glycine, a non-essential amino acid that enhances N-methyl-D-aspartate (NMDA) receptor mediated synaptic potentials in the neocortex of rats. Glycine is also being used as adjuvant therapy for the treatment of schizophrenia. Group: Biochemicals. Alternative Names: Gly-Gly, Diglycine;18: PN: WO2012015910 SEQID: 19 Unclaimed Sequence; 1: PN: WO2010117786 PAGE: 166 Claimed Protein; 2-(Aminoacetamido)acetic Acid; 221: PN: EP2161028 PAGE: 11 Claimed Protein; 31: PN: FR2860236 PAGE: 10 Claimed Protein; 36: PN: EP2204377 SEQID: 36 Claimed Protein; 36: PN: WO2010076654 SEQID: 36 Claimed Protein; 69: PN: US20110195077 SEQID: 14 Claimed Sequence; 6: PN: WO2013027191 SEQID: 14 Claimed Sequence; Diglycine; Diglycocoll; Gly2; Glycine Dipeptide; N-Glycylglycine; NSC 49346; α-Glycylglycine. Grades: Molecular Biology Grade. CAS No. 556-50-3. Pack Sizes: 100g, 250g, 500g, 1Kg, 5Kg. Molecular Formula: C?H?N?O?, Molecular Weight: 132.12. US Biological Life Sciences. | Worldwide |
| GSK3117391 | GSK3117391, a HDAC inhibitor, was developed by GSK considering its potential effect in the treatment of arthritis and rheumatoid. It was already being terminated the phase 1 trial. Uses: Gsk3117391, a hdac inhibitor, was developed by gsk considering its potential effect in the treatment of arthritis and rheumatoid. Synonyms: GSK3117391; GSK-3117391; GSK 3117391; GSK3117391A; GSK-3117391A; GSK 3117391A; HDAC-IN-3; SCHEMBL15144242; AFDPFLDWOXXHQM-NRFANRHFSA-N; CS-5448; HY-19772; 121555-EP2295410A1. Grades: 95%. CAS No. 1018673-42-1. Molecular formula: C22H33N3O4. Mole weight: 403.52. | |
| Indoline | Indoline. Uses: As an indole derivative, indoline can be used in the preparation of various medicinal compounds such as potential α1-adrenoceptor (α1-ar) antagonists. Additional or Alternative Names: AI3-39164; 15617-EP2311829A1; 2,3-dihydro-1 H-indole; aza-indane; 27157-EP2314575A1; Indoline, Vetec(TM) reagent grade, 98%; AC1Q1H8F; DTXSID9052133; 15617-EP2295429A1; 15617-EP2305648A1. Product Category: Indoles. CAS No. 496-15-1. Molecular formula: C8H9N. Mole weight: 119.167g/mol. IUPACName: 2,3-dihydro-1H-indole. Canonical SMILES: C1CNC2=CC=CC=C21. ECNumber: 207-816-8. Product ID: ACM496151. Alfa Chemistry ISO 9001:2015 Certified. | |
| L-161,982 | L-161,982 is a selective and potent EP4 receptor antagonist with Ki value of 0.024 μM. It is selective over all other members of the prostanoid receptor family with Ki values of 19, 23 and 1.90μM for human EP1, EP2 and EP3 receptors respectively. It suppresses PGE2-induced bone formation in young rats at 10 mg/kg/day and prevents the nociceptive response induced by misoprostol in formalin-injected mice. It reverses the anti-inflammatory action of PGE2 in LPS-activated human macrophages at 100 nM. It blocks PGE2-induced cell proliferation in HCA-7 colon cancer cells at 10 μM. Synonyms: L-161,982; L 161,982; L161,982; N-[[4'-[[3-Butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfonyl]-3-methyl-2-thiophenecarboxamide. Grades: ≥99% by HPLC. CAS No. 147776-06-5. Molecular formula: C32H29F3N4O4S2. Mole weight: 654.72. | |
| L-Cysteinylglycine-13C2 ,15N | L-Cysteinylglycine-13C2 ,15N. Group: Biochemicals. Alternative Names: N-L-Cysteinylglycine-13C2 ,15N; 144: PN: US20130123467 SEQID: 173 Claimed Protein-13C2 ,15N; 145: PN: WO2012013136 SEQID: 39 Unclaimed Protein-13C2 ,15N; 27: PN: WO2011133608 TABLE: 5 Claimed Sequence-13C2 ,15N; 52: PN: EP2161028 PAGE: 10 Claimed Protein-13C2 ,15N; 6: PN: WO2011003622 SEQID: 6 Claimed Protein-13C2 ,15N; Cysteinylglycine-13C2 ,15N; L-Cysteinylglycine-13C2 ,15N. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C313C2H10N15NO3S, Molecular Weight: 181.19. US Biological Life Sciences. | Worldwide |
| L-Histidine (L-His-OH) | L-Histidine is an essential amino acid for human development which the body cannot produce on its own. L-Histidine is one of the 22 proteinogenic amino acids. L-Histidine precursor to histamine and a component of carnosine. Group: Biochemicals. Alternative Names: L-His-OH; (2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic Acid; (S)-Histidine; L-(-)-Histidine; (S) -4- (2-Amino-2-carboxyethyl) imidazole; (S)-α-Amino-1H-imidazole-4-propanoic Acid; 1448: PN: EP2071334 SEQID: 1532 claimed protein; NSC 137773; 1448: PN: WO2009077864 SEQID: (S)-1H-Imidazole-4-alanine; PN: WO2009046220 SEQID: 343 claimed sequence; Glyoxaline-5-alanine; Histidine;3-(1H-Imidazol-4-yl)-L-alanine. Grades: Cell Culture Grade. CAS No. 71-00-1. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C6H9N3O2, Molecular Weight: 155.16. US Biological Life Sciences. | Worldwide |
| L-Leucine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolites. Alternative Names: Leucine, (S)-2-amino-4-methylpentanoic acid, Leucine, L- (8CI), (2S)-2-Amino-4-methylpentanoic acid, (S)-(+)-Leucine, (S)-2-Amino-4-methylpentanoic acid, (S)-2-Amino-4-methylvaleric acid, (S)-Leucine, 100: PN: US20070066537 PAGE: 17 claimed protein, 124: PN: EP2071334 SEQID: 136 claimed protein, 124: PN: WO2009077864 SEQID: 136 claimed protein, 164: PN: WO2010045512 SEQID: 173 unclaimed protein, 325: PN: WO2010059829 SEQID: 353 unclaimed protein, 45: PN: WO2008005407 PAGE: 5 claimed protein, 8: PN: US20090069547 PAGE: 10 claimed protein, L-(+)-Leucine, L-2-Amino-4-methylpentanoic acid, L-Norvaline, 4-methyl-, L-alpha-Aminoisocaproic acid, Leu, NSC 46709, Pentanoic acid, 2-amino-4-methyl-, (S)-,Phenylalanine Imp. A (EP). |  |
| L-Phenylalanine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolites. Alternative Names: L-Phenylalanine, 175: PN: WO2009077864 SEQID: 191 claimed protein, Antibiotic FN 1636, 3-Phenyl-L-alanine, (S)-2-Amino-3-phenylpropanoic acid, L-(-)-Phenylalanine, Tyrosine Imp. A (EP), NSC 79477, Aspartame Imp. C (EP), Benzenepropanoic acid, alpha-amino-, (S)-, (-)-Phenylalanine, L-Alanine, 3-phenyl-, 151: PN: US20070015162 SEQID: 161 claimed protein, (S)-alpha-Aminobenzenepropanoic acid, 11: PN: US20090069547 PAGE: 10 claimed protein,Nateglinide Imp. D (EP), 49: PN: WO2010069074 SEQID: 47 claimed sequence, (S)-alpha-Amino-beta-phenylpropionic acid, (S)-Phenylalanine, Alanine, phenyl-, L- (4CI,7CI,8CI), (S)-(-)-Phenylalanine, (S)-2-Amino-3-phenylpropionic acid, 34: PN: AU2005201745 SEQID: 22 claimed protein, 356: PN: US20070026454 SEQID: 366 claimed protein, 3-Phenylalanine, Phenyl-alpha-alanine, GV 112054X, 175: PN: EP2071334 SEQID: 191 claimed protein, beta-Phenyl-L-alanine, Phenylalanine, beta-Phenyl-alpha-alanine, (2S)-2-Amino-3-phenylpropanoic acid, (S)-alpha-Aminohydrocinnamic acid. | |
| L-Serine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolites. Alternative Names: Serine, (S)-2-amino-3-hydroxypropanoic acid,, (-)-Serine, (S)-2-Amino-3-hydroxypropanoic acid, (S)-Serine, (S)-alpha-Amino-beta-hydroxypropionic acid, 1: PN: US20090069547 PAGE: 10 claimed protein, 225: PN: EP2071334 SEQID: 242 claimed protein, 225: PN: WO2009077864 SEQID: 242 claimed protein, 6: PN: WO2012061268 SEQID: 6 claimed protein, L-(-)-Serine, L-3-Hydroxy-2-aminopropionic acid, L-Ser, beta-Hydroxy-L-alanine. | |
| L-Serine-13C3,15N | Isotope labelled L-Serine is used in the synthesis of purines and pyrimidines as antibacterial / antifungal agents, as well as acting as a proteinogenic compound. Group: Biochemicals. Alternative Names: (-)-Serine -13C3,15N; (S)-2-Amino-3-hydroxypropanoic Acid -13C3,15N; (S)-Serine -13C3,15N; (S)-α-Amino- β-hydroxypropionic Acid -13C3,15N; 1: PN: US20090069547 PAGE: 10 claimed protein -13C3,15N; 225: PN: EP2071334 SEQID: 242 claimed protein -13C3,15N; 225: PN: WO2009077864 SEQID: 242 claimed protein -13C3,15N; 6: PN: WO2012061268 SEQID: 6 claimed protein-13C3,15N; L-(-)-Serine-13C3,15N; L-3-Hydroxy-2-aminopropionic Acid -13C3,15N; 3-Hydroxy-L-alanine -13C3,15N; L-Ser; Serine -13C3,15N; β-Hydroxy-L-alanine -13C3,15N. Grades: Highly Purified. CAS No. 202407-34-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| L-Serine (L-Ser-OH) | Serine (abbreviated as Ser or S)[3] encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ?-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated ?NH+ 3 form under biological conditions), a carboxyl group (which is in the deprotonated -COO? form in physiological conditions), and a side chain consisting of a hydroxymethyl group (see hydroxyl), classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid. Group: Biochemicals. Alternative Names: L-Ser-OH; (-)-Serine; (S)-2-Amino-3-hydroxypropanoic Acid; (S)-Serine; (S)-α-Amino- β-hydroxypropionic Acid; 1: PN: US20090069547 PAGE: 10 claimed protein; 225: PN: EP2071334 SEQID: 242 claimed protein; 225: PN: WO2009077864 SEQID: 242 claimed protein; 6: PN: WO2012061268 SEQID: 6 claimed protein; L-(-)-Serine; L-3-Hydroxy-2-aminopropionic Acid; 3-Hydroxy-L-alanine; L-Ser; β-Hydroxy-L-alanine. Grades: Cell Culture Grade. CAS No. 56-45-1. Pack Sizes: 100g, 250g, 500g, 1Kg, 2.5Kg. Molecular Formula: C3H7NO3, Molecular Weight: 105.09. US Biological Life Sciences. | Worldwide |
| L-Valine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesnutritional composition compoundspharma & vet compounds & metabolitesphytochemicalsbuilding blocks. Alternative Names: L-alpha-Amino-beta-methylbutyric acid, 2-Amino-3-methylbutanoic acid, (S)-alpha-Amino-beta-methylbutyric acid, (S)-2-Amino-3-methylbutyric acid, (S)-2-amino-3-methylbutanoic acid, (S)-Valine, 80: PN: EP2071334 SEQID: 89 claimed protein, (+)-2-Amino-3-methylbutyric acid, L-(+)-alpha-Aminoisovaleric acid,Valine, (S)-2-Amino-3-methylbutanoic acid, 80: PN: WO2009077864 SEQID: 89 claimed protein, (2S)-2-Amino-3-methylbutanoic acid, 7: PN: US20090069547 PAGE: 10 claimed protein, NSC 76038. | |
| Maridomycin V | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: Antibiotic B 5050E; Turimycin EP2; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 4B-acetate 3-propanoate, (12S,13S)-. Grades: ≥95%. CAS No. 35942-57-5. Molecular formula: C40H65NO16. Mole weight: 815.94. | |
| Methyltri-n-octylammonium Chloride | Methyltri-n-octylammonium Chloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 102055-EP2275469A1; Aliquat 336; UNII-07Q8S2MJ6A; N-Methyl-N,N-dioctyl-1-octanaminium chloride; EINECS 225-896-2; methyl(trioctyl)azanium chloride; 93810-EP2305625A1; methyl trioctylammonium chloride; XKBGEWXEAPTVCK-UHFFFAOYSA-M; NSC 61369. Product Category: Ammonium Ionic Liquids. CAS No. 5137-55-3. Molecular formula: C25H54ClN. Mole weight: 404.164g/mol. IUPACName: methyl(trioctyl)azanium;chloride. Canonical SMILES: CCCCCCCC[N+](C)(CCCCCCCC)CCCCCCCC.[Cl-]. ECNumber: 225-896-2. Product ID: ACM5137553. Alfa Chemistry ISO 9001:2015 Certified. Categories: Methyltrioctylammonium chloride. | |
| N-Glycylproline | N-Glycylproline was found to exhibit anti-ischemic effects on the metabolism of neuroactive amino acids and indices of energy turnover in the neocortex of rats after experimental brain ischemia. Substrate for Prolidase. Group: Biochemicals. Alternative Names: (S) -1- (2-Aminoacetyl) pyrrolidine-2-carboxylic Acid; 1-Glycylproline; 11: PN: CN101988058 SEQID: 11 Claimed Sequence; 12: PN: WO2011133608 TABLE: 5 Claimed Sequence; 132: PN: US20130123467 SEQID: 158 claimed protein; 152: PN: EP2161028 PAGE: 10 Claimed Protein; 2: PN: WO2011150133 PAGE: 63 Claimed Sequence; 7: PN: WO03052099 PAGE: 83 Claimed Protein; 81: PN: WO2011146121 PAGE: 115 Claimed Sequence; Glycyl-L-proline; N-Glycyl-L-proline; NSC 97929. Grades: Purified. CAS No. 704-15-4. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Omidenepag | Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC 50 of 1.1 nM. Omidenepag shows binding affinities (IC 50 ) 10 nM for h-EP2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-7276. CAS No. 1187451-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17642. | |
| Omidenepag isopropyl | Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration, and Omidenepag is a highly selective EP2 receptor agonist. Omidenepag isopropyl shows only weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropyl is under development for the treatment of glaucoma as an intraocular pressure (IOP)-lowering agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DE-117. CAS No. 1187451-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111406. | |
| PF 04418948 | PF 04418948 acts as a novel, potent and selective prostoglandin EP2 receptor antagonist. Group: Biochemicals. Alternative Names: (1-(-fluorbenzoyl)-3-{[(6-methoxy-2-napthyl)oxy]methyl} Azetidine-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-04418948 | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Synonyms: PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948. Grades: 98%. CAS No. 1078166-57-0. Molecular formula: C23H20FNO5. Mole weight: 409.41. | |
| PF-4217329 | PF-04217329 is a potent and selective EP2 receptor agonist on intraocular pressure in preclinical models of glaucoma. It is a prodrug of CP-544326. It is well tolerated in preclinical species. Uses: Pf-04217329 is useful for intraocular pressure of glaucoma. Synonyms: PF-4217329, PF 4217329, PF4217329, PF-04217329, PF04217329, PF 04217329, Taprenepag isopropyl; Propan-2-yl 2- [3- [ [ (4-pyrazol-1-ylphenyl) methyl-pyridin-3-ylsulfonylamino] methyl] phenoxy] acetate; PF4217329; PF-04217329; PF04217329; Isopropyl 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetate. Grades: >98 %. CAS No. 1005549-94-9. Molecular formula: C27H28N4O5S. Mole weight: 520.60. | |
| Prostaglandin A3 | Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively, in a radioligand binding assay. Synonyms: PGA3; (Z)-7-[(1R)-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 36614-31-0. Molecular formula: C20H28O4. Mole weight: 332.4. | |
| Prostaglandin E1 | Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K i s of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3 , EP4 , EP2 , IP and EP1 , respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Alprostadil; PGE1. CAS No. 745-65-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0131. | |
| (R)-(+)-BINAP | (R)-(+)-BINAP. Uses: (r)-binap or (r)-tol-binap can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to noyori catalyst systems. these systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. noyori catalyst systems have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are. Additional or Alternative Names: -Bis(diphenylphosphino)-1,1; AK-46295; (s)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl; (S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1'1-BINAPHTHYL; 98327-87-8; PubChem12874; MUALRAIOVNYAIW-UHFFFAOYSA-N; (rac)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; 156196-EP2284169A1; (R)-(+)-2,2'-Bis(diphenyphosphino)-1,1'-binaphthyl. Product Category: Organic Phosphine Compounds. CAS No. 76189-55-4. Molecular formula: C44H32P2. Mole weight: 622.688g/mol. IUPACName: [1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane. Canonical SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C(C4=CC=CC=C4C=C3)C5=C(C=CC6=CC=CC=C65)P(C7=CC=CC=C7)C8=CC=CC=C8. ECNumber: 616-304-7. Product ID: ACM76189554. Alfa Chemistry ISO 9001:2015 Certified. Categories: Raina Perez. | |
| (R)-Butaprost | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4978; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid methyl ester. Grades: ≥98%. CAS No. 69648-38-0. Molecular formula: C24H40O5. Mole weight: 408.6. | |
| (R)-Butaprost (free acid) | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid. Grades: ≥98%. CAS No. 215168-33-5. Molecular formula: C23H38O5. Mole weight: 394.6. | |
| Rivenprost | Rivenprost is a potent and selective agonist for the EP4 receptor. It is selective for EP4 receptor over EP3, EP2, and EP1 receptors with Ki values of 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively. It has been used to promote EP4-mediated bone formation, prevent bone loss related to osteoporosis, drive osteoblast differentiation, and stabilize bone implants. Synonyms: ONO-4819; Methyl 4- [2- [ (1R, 2R, 3R) -3-hydroxy-2- [ (E, 3S) -3-hydroxy-4- [3- (methoxymethyl) phenyl] but-1-enyl] -5-oxocyclopentyl] ethylsulfanyl] butanoate. Grades: ≥98%. CAS No. 256382-08-8. Molecular formula: C24H34O6S. Mole weight: 450.6. | |
| (S)-(-)-BINAP | (S)-(-)-BINAP. Uses: (r)-binap or (r)-tol-binap can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to noyori catalyst systems. these systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. noyori catalyst systems have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are. Additional or Alternative Names: (+)-2,2'-bis(diphenylphosphino)-1,1'binaphthyl; (R)-(+)-2,2 bis(diphenylphosphino)-1,1-binaphthyl; 13648-EP2311831A1; (R)-(+)-(1,1'-Binaphthalene-2,2'-diyl)bis(diphenylphosphine); FT-0604001; [2'-(diphenylphosphanyl)-[1,1'-binaphthalene]-2-yl]diphenylphosphane; 1,1'-[(1R)-[1,1'-BINAPHTHALENE]-2,2'-DIYL]BIS[1,1-DIPHENYL]-PHOSPHINE; 13648-EP2286811A1; racemic-2,2'-bis(diphenylphosphino)-1,1' binapht. Product Category: Organic Phosphine Compounds. CAS No. 76189-56-5. Molecular formula: C44H32P2. Mole weight: 622.688g/mol. IUPACName: [1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane. Canonical SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C(C4=CC=CC=C4C=C3)C5=C(C=CC6=CC=CC=C65)P(C7=CC=CC=C7)C8=CC=CC=C8. ECNumber: 616-304-7. Product ID: ACM76189565. Alfa Chemistry ISO 9001:2015 Certified. Categories: 98327-87-8, Singapore. | |
| Silver benzoate, 99% | Silver benzoate, 99%. Group: Solution deposition precursors. Alternative Names: AC1L4V6M; 114728-EP2292621A1; 114728-EP2298783A1; RTC-061599; UNII-AKL351M7YF; silver benzo-ate; Benzoic acid, silver(1+) salt; MFCD00013030 (95%); silverbenzoate; 532-31-0. CAS No. 532-31-0. Product ID: silver; benzoate. Molecular formula: 228.983g/mol. Mole weight: C7H5AgO2. C1=CC=C(C=C1)C(=O)[O-].[Ag+]. InChI=1S/C7H6O2. Ag/c8-7(9)6-4-2-1-3-5-6; /h1-5H, (H, 8, 9); /q; +1/p-1. CLDWGXZGFUNWKB-UHFFFAOYSA-M. | |
| SR-01000946410 | SR-01000946410 is a structural analog of PGE2 and a selective agonist for the EP2 receptor subtype. It binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor. It does not bind appreciably to any of the other murine EP receptors. BIt has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4979. Grades: ≥98%. CAS No. 69685-22-9. Molecular formula: C24H40O5. Mole weight: 408.6. | |
| TG 4-155 | TG 4-155 is a high affinity and selective EP2 receptor antagonist (KB = 2.4 and 34.5 nM for EP2 and DP1 receptors, respectively) displaying >500-fold selectivity over other prostanoid receptors. TG 4-155 inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro. Synonyms: TG4-155; TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155; (2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1164462-05-8. Molecular formula: C23H26N2O4. Mole weight: 394.46. | |
| TG4-155 | TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a K i of 9.9 nM [1] [2]. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1 [1]. TG4-155 has an EP2 Schild K B of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1164462-05-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18971. | |
| TG6-10-1 | TG6-10-1, a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2, has been shown antagonist activity at human EP2 receptor expressed in rat C6 cells. It shows low-nanomolar antagonist activity against EP2 (>300-fold selectivity ov. Synonyms: (E)-N-[2-[2-(trifluoromethyl)indol-1-yl]ethyl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamideTG6-10-1; TG 6-10-1; TG-6-10-1; TP6101; TP-6101; TP 6101. CHEMBL32642041415716-58-3C23H23F3N2O4BDBM50016950AKOS0274399 55CS-4637; AK-499428; HY-16978; CS 4637; AK 499428; HY 16978; CS4637; AK499428; HY16978(E)-N-(2-(2-(Trifluoromethyl)-1H-indol-1-yl)ethyl)-3-(3,4,5-trime. CAS No. 1415716-58-3. Molecular formula: C23H23F3N2O4. Mole weight: 448.43. | |
| TG6-129 | TG6-129 is an antagonist of the EP2 receptor, suppressing PGE2-induced elevation of cAMP in cells expressing EP2 with IC50 value of 1.6 μM. It reduces the expression of COX-2, IL-1β, IL-12, IL-23, IL-6, and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages. Synonyms: SID 17503974; (E)-N-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl]carbamothioyl]-3-(4-fluorophenyl)prop-2-enamide. Grades: ≥98%. CAS No. 1164464-14-5. Molecular formula: C20H18FN5O3S3. Mole weight: 491.6. | |
| Treprostinil | Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC 50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UT-15. CAS No. 81846-19-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100441. | |
| Treprostinil palmitil | Treprostinil palmitil (TP) is the proagent of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC 50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure proagent and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INS-1009. CAS No. 1706528-83-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109163. | |
| Treprostinil sodium | Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist with EC 50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UT-15 sodium. CAS No. 289480-64-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16504. | |
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