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| Product | Description | |
|---|---|---|
| Poly(2-methyl-2-oxazoline), hydroxy terminated | The hydrophilic polymer contains polar or charged functional groups, making it soluble in water. Uses: Poly(2-methyl-2-oxazoline) is a hydrophilic polymer that is commonly used in biomedical s. this is a biocompatible polymer with one chain-end functionalized with an oh group. they are commonly used as an amorphous alternative to peg's. Group: Hydrophilic polymers. Alternative Names: PMOx, POx 5kDa. Pack Sizes: Packaging 5 g in glass bottle. Molecular formula: average Mn 5,000. Mole weight: CH3(C4H7NO)nOH. 1S/C5H11NO2/c1-5(8)6(2)3-4-7/h7H, 3-4H2, 1-2H3. OBSKGKGKPGOOTB-UHFFFAOYSA-N. |  |
| Poly(Dimethylsiloxane), Bis(Hydroxyalkyl) Terminated | Poly(Dimethylsiloxane), Bis(Hydroxyalkyl) Terminated. Uses: Reactive resin modifier, paint additive and mold release agent. Group: Bioelectronic materials self assembly and lithography. Alternative Names: Hydroxy Terminated Polydimethylsiloxane; Poly(Dimethylsiloxane), Hydroxyethoxypropyl Terminated Carbinol (Hydroxyl) Terminated Polydimethylsiloxane. CAS No. 156327-07-0. Pack Sizes: 25, 100 mL in poly bottle. Product ID: 2-[3-[[3-(2-hydroxyethoxy)propyl-dimethylsilyl]oxy-dimethylsilyl]propoxy]ethanol. Molecular formula: 338.59g/mol. Mole weight: C14H34O5Si2. C[Si](C)(CCCOCCO)O[Si](C)(C)CCCOCCO. InChI=1S/C14H34O5Si2/c1-20(2, 13-5-9-17-11-7-15)19-21(3, 4)14-6-10-18-12-8-16/h15-16H, 5-14H2, 1-4H3. BGHSBLYBOOUZFE-UHFFFAOYSA-N. 0.97. | |
| Poly(dimethylsiloxane-co-diphenylsiloxane), dihydroxy terminated | 95:5 mole ratio of dimethlsiloxane:diphenylsiloxane. Group: Bioelectronic materials self assembly and lithography. Alternative Names: Hydroxy-terminated di-Me di-Ph siloxanes. CAS No. 68951-93-9. Pack Sizes: 25 mL in poly bottle. Product ID: hydroxy-[[[hydroxy (dimethyl)silyl]oxy-dimethylsilyl]oxy-diphenylsilyl]oxy-dimethylsilane. Molecular formula: 438.8g/mol. Mole weight: HOSi (C6H5)2O[Si (CH3)2O]x[Si (C6H5)2O]ySi (C6H5)2OH. C[Si] (C) (O)O[Si] (C) (C)O[Si] (C1=CC=CC=C1) (C2=CC=CC=C2)O[Si] (C) (C)O. InChI=1S/C18H30O5Si4/c1-24 (2, 19) 21-26 (5, 6) 23-27 (22-25 (3, 4) 20, 17-13-9-7-10-14-17) 18-15-11-8-12-16-18/h7-16, 19-20H, 1-6H3. ANESSQOBUVNCKY-UHFFFAOYSA-N. | |
| Poly(dimethylsiloxane), hydroxy terminated | Poly(dimethylsiloxane), hydroxy terminated. Uses: Component of silicone room temperature vulcanizing system that incorporates reinforcing aids or fillers. Group: Bioelectronic materials self assembly and lithography. Alternative Names: PDMS. CAS No. 70131-67-8. Pack Sizes: 250 mL in poly bottle. C[Si](C)(O)O. | |
| Poly(ethylene glycol) α-hydroxy-ω-azido terminated | Poly(ethylene glycol) α-hydroxy-ω-azido terminated. Group: Poly(ethylene glycol) and poly(ethylene oxide). | |
| Poly(ethylene oxide), 4-arm, hydroxy terminated | Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Molecular formula: average Mn 10000. | |
| Poly(ethylene oxide), 6-arm, hydroxy terminated | Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Molecular formula: average Mn 17000. | |
| Poly(hydroxyethyl methacrylate), DDMAT terminated | The polymer product is a hydrophobic material that is insoluble in water or other polar solvents. Uses: Poly(hydroxyethyl methacrylate) is a hydrophobic polymer which contains a hydrophilic hydroxy group. the end group functionality contains a carboxylic acid (cooh) as well as the 2-(dodecylthiocarbonothioylthio)-2-methylpropionic acid raft agent moiety. this will allow for additional polymerization to generate a diblock copolymer. this raft agent is especially suited for the polymerization of styrene; acrylate and acrylamide monomers. Group: other plastics. Alternative Names: PolyHEA, PHEA, PolyHEMA, PHEMA, RAFT polymer, Macro RAFT-CTA. Pack Sizes: 1 g in glass bottle. Molecular formula: average Mn 7,000. Mole weight: C4H7O2(C6H10O3)nC13H25S3. | |
| Siloxanes and silicones,di-me,3-[2-(hydroxy-3-[(1-oxo-2-propenyl)oxy]propoxy]propyl group-terminated | Heterocyclic Organic Compound. CAS No. 125455-52-9. Catalog: ACM125455529. |  |
| Siloxanes and silicones,di-me,me vinyl,hydroxy-terminated reaction products with trimethoxy[3-oxiranylmethoxy)propyl]silane | Heterocyclic Organic Compound. CAS No. 102782-94-5. Catalog: ACM102782945. | |
| Siloxanes andSilicones, di-Me, polymers with Me Ph silsesquioxanes, hydroxy-terminated | Heterocyclic Organic Compound. CAS No. 113355-05-8. Catalog: ACM113355058. | |
| SILOXANES AND SILICONES, METHYL VINYL HYDROXY-TERMINATED | Cas No. 68083-20-5. |  |
| 1,3-bis-Hydroxypropyl polydimethyl siloxane | Heterocyclic Organic Compound. Alternative Names: MONOCARBINOL TERMINATED POLYDIMETHYLSILOXANE; POLYDIMETHYLSILOXANE, CARBINOL TERMINATED;POLYDIMETHYLSILOXANE, HYDROXYL TERMINATED; siloxanesandsilicones, di-me, 3-hydroxypropylgroup-terminated; 3-[HYDROXY (POLYETHYLENEOXY) PROPYL]HEPTAMETHYLTRISILOXANE; 2-[HYDRO. CAS No. 104780-66-7. Density: 0,98 g/cm3. Catalog: ACM104780667. | |
| BMS561392 | BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA). It was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated. Uses: Bms561392 has the potential treatment of diseases characterized by overproduction of tnf alpha, such as rheumatoid arthritis (ra). Synonyms: BMS-561392; BMS561392; BMS 561392; DPC-333; DPC 333; DPC333. (αR,?3R)?-3-Amino-N-hydroxy-α-(2-methylpropyl)?-3-[4-[(2-methyl-4-quinolinyl)?methoxy]?phenyl]?-2-oxo-1-pyrrolidineacetamide?;BMS-561392;DPC-333;(2R)-2-[(3R)-3-amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hyd. Grades: 98%. CAS No. 611227-74-8. Molecular formula: C27H32N4O4. Mole weight: 476.57. | |
| Elubrixin | Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist. It is potentially useful for Inflammatory bowel disease therapies. It inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. It may be an effective agent in neutrophil-predominant diseases. It was developed by GlaxoSmithKline and was in clinic phase 2 trials, but now it is terminated. Uses: Elubrixin is potentially useful for inflammatory bowel disease therapies. it may be an effective agent in neutrophil-predominant diseases. Synonyms: 1-(2-Chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea;SB-656933;SB656933;SB-656933-AAF;SB-656933-AAA;SB656933AAA;SB656933AAF;1-(4-Chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea. Grades: 98%. CAS No. 688763-64-6. Molecular formula: C17H17Cl2FN4O4S. Mole weight: 463.30. | |
| Milveterol | Milveterol is a long-acting β(2)-adrenoceptor agonist. It is potentially useful for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It was developed by GlaxoSmithKline and Theravance together. It was in clinic phase 2 trials, but now it is terminated. Uses: Milveterol is potentially useful for the treatment of chronic obstructive pulmonary disease (copd) and asthma. Synonyms: GSK159797; GSK 159797; GSK-159797; N- [2-hydroxy-5- [ (1R) -1-hydroxy-2- [2- [4- [ [ (2R) -2-hydroxy-2-phenylethyl] amino] phenyl] ethylamino] ethyl] phenyl] formamide; GSK-159797. Grades: 98%. CAS No. 652990-07-3. Molecular formula: C25H29N3O4. Mole weight: 435.52. | |
| MK-0354 | MK-0354 is a partial agonist of Niacin receptor, G-protein coupled receptor 109a. Its EC50 value is 1.65/1.08 μM for hGPR109a/ mGPR109a, which show no activation of GPR109b in the cAMP assay at any concentration up to 100 μM. It demonstrated clear and statistically significant partial agonism in the cAMP assays for both the mouse and human receptors with efficacy approximately 60-70% of that of either nicotinic acid or β-hydroxy butyrate in vitro. It appeared to be somewhat unique among the members of the pyrazole tetrazole series in having reasonable receptor activity. It retained the plasma free fatty acid lowering effects in mice, but did not induce vasodilation at the maximum feasible dose in vivo. It could activate the antilipolytic pathway in adipocytes. It was developed by Arena pharmaceuticals and Merck Serono together. It had been in the two phase of clinical and been used for the treatment of atherosclerosis, but it was terminated in 2006. Uses: Mk-0354 could activate the antilipolytic pathway in adipocytes. had been used for the treatment of atherosclerosis. Synonyms: MK-0354; MK0354; MK 0354; 3-(1H-tetrazol-5-yl)-1, 4, 5, 6-tetrahydrocyclopenta[c]pyrazole;1, 4, 5, 6-Tetrahydro-3-(1H-tetrazol-5-yl)cyclopenta[c]pyrazole. Grades: >98%. CAS No. 851776-28-8. Molecular formula: C7H8N6. Mole weight: 176.18. | |
| Navarixin | Navarixin is a potent CXC chemokine receptor 2 (CXCR2) antagonist. It can be used for the treatment of Asthma and Chronic obstructive pulmonary disease. In Dec 2011, Merck terminated phase II trial in Chronic obstructive pulmonary disease. Uses: Asthma; chronic obstructive pulmonary disease. Synonyms: SCH 527123; MK 7123; PS 291822; SCH527123; MK7123; PS291822; SCH-527123; MK-7123; PS-291822; (R)-2-hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide. Grades: 98%. CAS No. 862464-58-2. Molecular formula: C21H23N3O5.H2O. Mole weight: 428.48. | |
| POLY(STYRENE-CO-MALEIC ACID), PARTIAL PROPYL ESTER, CUMENE TERMINATED | POLY(STYRENE-CO-MALEIC ACID), PARTIAL PROPYL ESTER, CUMENE TERMINATED. Group: Polymers. CAS No. 160611-48-3. Product ID: benzylN-[(2S)-1-[[(2S,3S,5R)-3-hydroxy-5-[5-(2-methylpropanoyl)-1H-imidazol-2-yl]-1,6-diphenylhexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate. Molecular formula: 638.79564;g/mol. Mole weight: C38H46N4O5. CC (C)C (C (=O)NC (CC1=CC=CC=C1)C (CC (CC2=CC=CC=C2)C3=NC=C (N3)C (=O)C (C)C)O)NC (=O)OCC4=CC=CC=C4. RQAVEWKEUKIFLD-LVPKLHHISA-N. 96%. | |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grades: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. | |
| TAK-700 | TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). It completed two phase III clinical trials for metastatic, hormone-refractory prostate cancer but failed to extend overall survival rates, and development was voluntarily terminated as a result. Synonyms: TAK-700; TAK700; (S/R)-Orteronel; 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide. Grades: >98%. CAS No. 426219-18-3. Molecular formula: C18H17N3O2. Mole weight: 307.35. | |
| 1-Hydroxy-1,2-benziodoxol-3(1H)-one | 1-?Hydroxy-?1,?2-?benziodoxol-?3(1H)?-?one (IBA) is an efficient terminal oxidant for gold-?catalyzed, three-?component oxyarylation reactions. It also acted as a catalyst in synthesis of ynones via a hypervalent iodine-catalyzed reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 131-62-4. Pack Sizes: 1g, 10g. Molecular Formula: C7H5IO3, Molecular Weight: 264.02. US Biological Life Sciences. |  Worldwide |
| 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine | 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine is a nucleoside analog used as an antiviral drug against hepatitis B virus (HBV) and hepatitis C virus (HCV). It inhibits viral polymerase activity and causes chain termination during viral genome replication, thus reducing viral load in infected individuals. This product has potential as a therapeutic agent against other RNA viruses such as Ebola and Zika. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinoribofuanosyl)-2(1H)-pyrimidinone; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-Arafluorozebularine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)pyrimidin-2-(1H)-one. Grades: ≥95%. CAS No. 136675-88-2. Molecular formula: C9H11FN2O4. Mole weight: 230.19. | |
| 2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine | 2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine is a potent antiviral nucleoside analog used in the treatment of viral infections, specifically targeting RNA viruses. It inhibits viral replication by incorporating into viral RNA and terminating its synthesis. This product is commonly used in biomedical research to study the mechanisms of viral replication and to develop new antiviral therapies. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil; 1-Dfafeu; FEAU; 5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 83546-42-3. Molecular formula: C11H15FN2O5. Mole weight: 274.25. | |
| 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-a-D-arabinouridine | 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-a-D-arabinouridine is a nucleoside analog used as an antiviral drug to treat hepatitis B and C virus infections. It inhibits viral replication by incorporating into viral DNA and terminating chain elongation. It also exhibits antitumor activity by inhibiting DNA synthesis in cancer cells. Synonyms: 1-[(2S,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-alpha-D-arabino-pentofuranosyl)-5-methyluracil; 1-(2-Deoxy-2-fluoro-4-thio-alpha-D-arabinofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-(2-Deoxy-2-fluoro-4-thio-α-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 294868-24-9. Molecular formula: C10H13FN2O4S. Mole weight: 276.28. | |
| 2'-Deoxy-a-guanosine | 2'-Deoxy-a-guanosine is a nucleoside analog of pivotal significance, demonstrating profound antiviral attributes. This esteemed compound orchestrates a masterstroke by impeding viral DNA replication, thereby functioning as an indomitable chain terminator. Synonyms: 2-amino-9-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5H-purin-6-one. Grades: ≥ 98% (HPLC). CAS No. 19916-78-0. Molecular formula: C10H13N5O4. Mole weight: 267.25. | |
| 2-heptyl-3-hydroxy-4(1H)-quinolone synthase | The enzyme from the bacterium Pseudomonas aeruginosa catalyses the terminal step in biosynthesis of the signal molecule 2-heptyl-3,4-dihydroxyquinoline that plays a role in regulation of virulence genes. Group: Enzymes. Synonyms: PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Enzyme Commission Number: EC 1.14.13.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0781; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase; EC 1.14.13.182; PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Cat No: EXWM-0781. |  |
| 2'-O-Methylguanosine-5'-triphosphate trilithium salt | 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00. | |
| 2'-O-Methyluridine-5'-triphosphate | 2'-O-Methyluridine-5'-triphosphate is a nucleotide analog commonly used in biochemistry research. It can be used as a substrate for RNA polymerases or as a terminoligical ATP analog for use in RNA synthesis reactions. Its effectiveness as an antiviral and antitumor agent is also being investigated. Synonyms: 2'-methoxy-UTP; 2'-O-Methyluridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-; 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine; 2'-O-Methyluridine 5'-(tetrahydrogen triphosphate); ({[ ({[ (2R, 3R, 4R, 5R)-5- (2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy} (hydroxy)phosphoryl)oxy] (hydroxy)phosphoryl}oxy)phosphonic acid. Grades: ≥97% by HPLC. CAS No. 143028-99-3. Molecular formula: C10H17N2O15P3. Mole weight: 498.17. | |
| 2'-TFA-NH-2'-Deoxyuridine | 2'-TFA-NH-2'-Deoxyuridine is a nucleoside analogue that has been used to treat certain viral infections and cancers. It is incorporated into the DNA of the target cells, causing chain termination and preventing further replication. Its antiviral activity has been observed against herpes simplex virus types 1 and 2, as well as varicella zoster virus. It has also shown promise in slowing the growth of certain tumors. Synonyms: 2'-TFA-NH-dU; 2'-trifluoroacetamido-2'-deoxyuridine; Uridine, 2'-deoxy-2'-[(trifluoroacetyl)amino]-; 2'-Deoxy-2'-[(trifluoroacetyl)amino]uridine; Uridine, 2'-deoxy-2'-[(2,2,2-trifluoroacetyl)amino]-; N-((2R,3R,4S,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)-2,2,2-trifluoroacetamide. Grades: ≥97% by HPLC. CAS No. 51989-21-0. Molecular formula: C11H12F3N3O6. Mole weight: 339.22. | |
| 3'-Azido-3'-deoxy-5-fluoro-beta-L-cytidine | 3'-Azido-3'-deoxy-5-fluoro-beta-L-cytidine is a nucleoside analogue that inhibits viral replication by terminating DNA synthesis. It is currently being used to treat hepatitis B and HIV infections. This drug works by being selectively incorporated into viral DNA, causing chain termination and preventing further synthesis. It has also shown promise in treating certain types of cancer by inhibiting cell proliferation and inducing apoptosis. Synonyms: 4-amino-1-[(2S,3S,4R,5R)-4-azido-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one. Grades: ≥95%. CAS No. 2095417-76-6. Molecular formula: C9H11FN6O4. Mole weight: 286.22. | |
| (3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate | PyAOP is a phosphonium salt used as a coupling reagent in Solid-phase peptide synthesis, without undergoing side reactions with the amino terminus. PyAOP is a derivative of HOAt. Synonyms: PyAOP; (7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE; 7-AZABENZOTRIAZOL-1-YLOXY-TRIS-(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; (7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE; PYAOP; ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate; (T-4)?-[3-(hydroxy-κO)?-3H-1,?2,?3-triazolo[4,?5-b]?pyridinato]?tri-1-pyrrolidinyl-Phosphorus(1+)? hexafluorophosphate(?1-); tri-1-pyrrolidinyl(3H-1,2,3-triazolo[4,5-b]pyridin-3-yloxy)-Phosphonium hexafluorophosphate(1-). Grades: 98%. CAS No. 156311-83-0. Molecular formula: C17H27N7OP?PF6. Mole weight: 521.38. | |
| 3-ketosteroid 9α-monooxygenase | The enzyme is involved in the cholesterol degradation pathway of several bacterial pathogens, such as Mycobacterium tuberculosis. It is a two-component system consisting of a terminal oxygenase (KshA) and a ferredoxin reductase (KshB). The oxygenase contains a Rieske-type iron-sulfur center and non-heme iron. The reductase component is a flavoprotein containing an NAD-binding domain and a plant-type iron-sulfur cluster. The product of the enzyme is unstable, and spontaneously converts to 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione. Group: Enzymes. Synonyms: KshAB; 3-ketosteroid 9α-hydroxylase. Enzyme Commission Number: EC 1.14.13.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0742; 3-ketosteroid 9α-monooxygenase; EC 1.14.13.142; KshAB; 3-ketosteroid 9α-hydroxylase. Cat No: EXWM-0742. | |
| 5'-Amino-2',5'-dideoxyuridine | 5'-Amino-2',5'-dideoxyuridine is an imperative nucleoside analogue of significant relevance in the biomedical sector is effectively harnessed for addressing the ubiquitous viral diseases encompassing herpes and HIV. Distinguished by its remarkable characteristic, this compound effectively obstructs the progression of viral DNA synthesis through its adeptness at terminating replication chains. Moreover, its commendable antiviral attributes render it a promising candidate in the realm of therapeutic agent advancement, effectively countering the virulent onslaught of diverse viral infections. Synonyms: Uridine, 5'-amino-2',5'-dideoxy-; NSC 175992; 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 35959-38-7. Molecular formula: C9H13N3O4. Mole weight: 227.22. | |
| 5-Methyl-3'-deoxyuridine | It is a uridine analogue and RNA chain terminator. Synonyms: 3'-Deoxy-5-methyluridine; 1-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(3-Deoxy-β-D-erythro-pentofuranosyl)-thymine; 3'-Deoxy-5-methyl-uridine. Grades: ≥95%. CAS No. 7084-29-9. Molecular formula: C10H14N2O5. Mole weight: 242.23. | |
| 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine | 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine, known for its potent antiviral properties, has become a pivotal component in research of combatting viral infections induced by herpes simplex viruses (HSV). Functionally, it obtrudes viral DNA replication by inducing chain termination throughout the process of viral DNA research and development. Synonyms: 5-TFA-aha-2'-deoxyuridine; TFA-aha-dU; 2'-Deoxy-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-uridine; 5-TFA-aha-dU; uridine, 2'-deoxy-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-; (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide. Grades: ≥98% by HPLC. CAS No. 252337-58-9. Molecular formula: C20H27F3N4O. Mole weight: 396.45. | |
| 6-Hydroxy Dopamine Hydrochloride | 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells. Group: Biochemicals. Alternative Names: 2, 4, 5-Trihydroxyphene thylamine Hydrochloride; 5-(2-Aminoethyl)-1,2,4-benzenetriol Hydrochloride; 6-Hydroxydopamine Hydrochloride; Oxidopamine Hydrochloride; Topamine Hydrochloride. Grades: Highly Purified. CAS No. 28094-15-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| APHA Compound 8 | APHA Compound 8 is a synthetic HDAC (histone deacetylase) inhibitor, which is in the same structural class as SAHA. The IC50 for mouse HDAC1 is 0.5 μM. It induces histone hyperacetylation, growth inhibition, and terminal cell differentiation. Synonyms: MC-1353; MC1353; MC 1353; APHA-8; APHA Compound 8; Aroyl pyrrole hydroxy amide #8; APHA 8; APHA8. Grades: ≥98%. CAS No. 676599-90-9. Molecular formula: C16H16N2O3. Mole weight: 284.3. | |
| CAY10580 | Prostaglandin E2 is a naturally occurring prostaglandin which is used as a medication. As a medication it is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It selectively binds the EP4 receptor with Ki of 35 nM. Synonyms: CAY 10580; CAY-10580. Grades: ≥96%. CAS No. 64054-40-6. Molecular formula: C19H35NO4. Mole weight: 341.5. | |
| CEP 1347 | CEP 1347, also named KT 7515 or CHEMBL290352, an ethylthiomethyl derivative, is a potent, selective inhibitor of the cJun-amino terminal kinase pathway currently under clinical evaluation for the treatment of neurodegenerative diseases. It blocks Aβ-induced cortical neuron apoptosis (EC50 ~51 nM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CHEMBL290352; CEP-1347; 3,9-Bis(etsm)-K-252a; CEP1347; 156177-65-0; CEP 1347; KT7515; 3,9-Bis((ethylthio)methyl)-K-252a; KT 7515; KT-7515; GTPL8173; SCHEMBL12047710; BDBM24942; CEP1374; CEP 1374; CEP-1374; ZINC3928304; AKOS024458422; KT-1575; 170587-65-2; 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 5,16-bis((ethylthio)methyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S-(9alpha,10beta,12alpha))-; CEP 1347|(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester; methyl (15S, 16R, 18R)-10, 23-bis[(ethylsulfanyl)methyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4, 14, 19-triazaoctacyclo[12.11.2.1^{15, 18}.0^{2, 6}.0^{7, 27}.0^{8, 13}.0^{19, 26}.0^{20, 25}]octacosa-1, 6, 8, 10, 12, 20, 22, 24, 26-nonaene-16-carboxylate. CAS No. 156177-65-0. Molecular formula: C33H33N3O5S2. Mole weight: 615.76. | |
| CEP 1347 | Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20nM). Blocks A β-induced cortical neuron apoptosis (EC50 ~51nM). Does not inhibit ERK1 activity. Neuroprotective. Group: Biochemicals. Alternative Names: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester. Grades: Highly Purified. CAS No. 156177-65-0. Pack Sizes: 1mg. Molecular Formula: C33H33N3O5S2.1?2H2O, Molecular Weight: 624.77. US Biological Life Sciences. | Worldwide |
| (+)-Cloprostenol isopropyl ester | (+)-Cloprostenol isopropyl ester is a derivative of cloprostenol which has been found to be a FP receptor agonist as well as a luteolytic agent and could be used commonly as a veterinary drug for its effect in terminating pregnancy. Synonyms: (+)-Cloprostenol isopropyl ester; HE113833; LP014937; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z), 2β(1E, 3R*), 3α, 5α]]-7-[2-[4-(3-Chlorophenoxy)-3-hy. Grades: 98%. CAS No. 157283-66-4. Molecular formula: C25H35ClO6. Mole weight: 466.99. | |
| DSPE-PEG5-propargyl | CuAAC & Thiol-Yne & Spontaneous Amino-Yne Click Reaction. Group: Terminal alkynes. CAS No. 2112737-93-4. Molecular formula: C55H104NO14P. Mole weight: 1034.39. IUPACName: [ (2R) -3- [Hydroxy- [2- [3- [2- [2- [2- (2-prop-2-ynoxyethoxy) ethoxy] ethoxy] ethoxy] propanoylamino] ethoxy] phosphoryl] oxy-2-octadecanoyloxypropyl] octadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCCCC (=O)OCC (COP (=O) (O)OCCNC (=O)CCOCCOCCOCCOCCOCC#C)OC (=O)CCCCCCCCCCCCCCCCC. Catalog: CCR2112737934. | |
| Epicoccamide | It is an ornate linear fatty acid with an acyl tetronic acid terminus and glycosidic alkyl terminus. It is originally isolated from epicoccum purpurascens. It is non-cytotoxic, unlike the weak activity shown by related analogues Epicoccamides B, C and D. Synonyms: 5-hydroxy-1,2-dimethyl-4-(2-methyl-16-(((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexadecanoyl)-1,2-dihydro-3H-pyrrol-3-one; 1,2-Dihydro-5-hydroxy-4-[16-(β-D-mannopyranosyloxy)-2-methyl-1-oxohexadecyl]-1,2-dimethyl-3H-pyrrol-3-one. Grades: >98% by HPLC. CAS No. 606139-26-8. Molecular formula: C29H51NO9. Mole weight: 557.72. | |
| Fluorescein Alkynylamino-ATP | Fluorescent ribonucleotides as substrates in terminal transferase-catalyzed labeling of DNA sequencing primers. Synonyms: N-[6-[[3-[4-Amino-7-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-7H-pyrrolo[2, 3-d]pyrimidin-5-yl]-2-propynyl]amino]-6-oxohexyl]-3', 6'-dihydroxy-3-oxospiro[isobenzofuran-1 (3H) , 9'-[9H]xanthene]-ar-carboxamide. CAS No. 185971-89-5. Molecular formula: C41H41N6O20P3. Mole weight: 1030.71. | |
| Fmoc-D-Glu-ODmab | Fmoc-D-Glu-ODmab is a glycine-extended peptide that is used as a resin-bound peptide for solid-phase peptide synthesis. The D-glutamic acid residue has a higher chemical stability compared to L-glutamic acid, which makes it a suitable component for peptide synthesis. The Fmoc group serves as a protecting group for the amino group, which is removed during the peptide elongation process. The ODmab group serves as a C-terminal protecting group that can be removed using mild acidic conditions. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Glu-ODmab, N-α-Fmoc-D-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester. CAS No. 874486-65-4. Molecular formula: C40H44N2O8. Mole weight: 680.79. IUPACName: (4R) -4- (9H-fluoren-9-ylmethoxycarbonylamino) -5- [ [4- [ [1- (2-hydroxy-4, 4-dimethyl-6-oxocyclohexen-1-yl) -3-methylbutylidene] amino] phenyl] methoxy] -5-oxopentanoic acid. Canonical SMILES: CC (C)CC (=NC1=CC=C (C=C1)COC (=O)C (CCC (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C5=C (CC (CC5=O) (C)C)O. Catalog: ACM874486654. | |
| Fpg Protein from Escherichia coli, Recombinant | Fpg protein, a key enzyme in the DNA base excision repair pathway (BER), catalyses the excision of a broad spectrum of modified purines such as formamidopyrimidine (Fapy) and 8-oxoguanine (8-oxo-G). Fpg possess both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose, leaving both 5'-and 3'-phosphorylated ends in the DNA. Several analytical methods based on Fpg protein activity in vitro were developed for detection and quantitation of oxidative damage to DNA mainly for FapyA, FapyG and 8-oxo-G. The fpg gene was cloned by Boiteux, et al. Fpg protein possess a zinc finger motif at its C-terminus (one zinc atom per molecule). ... Protein. Mole weight: mol wt 30.2 kDa (269 amino acids, predicted from the nucleotide sequence). Activity: >20 ,000 units/mg protein. Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50% glycerol containing 50 mM potassium HEPES, pH 7.5, 1 mM DTT, 1 mM EDTA, and 200 mM NaCl. Source: E. coli. Species: Escherichia coli. Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5 (N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein; DNA-formamidopyrimidine glycosylase; EC 3.2.2.23; 78783-53-6; | |
| lipid-phosphate phosphatase | Requires Mg2+ for maximal activity. The enzyme from mammals is a bifunctional enzyme: the N-terminal domain exhibits lipid-phosphate-phosphatase activity and the C-terminal domain has the activity of EC 3.3.2.10, soluble epoxide hydrolase (sEH). The best substrates for this enzyme are 10-hydroxy-9-(phosphonooxy)octadecanoates, with the threo- form being a better substrate than the erythro- form. The phosphatase activity is not found in plant sEH or in EC 3.3.2.9, microsomal epoxide hydrolase, from mammals. Group: Enzymes. Synonyms: hydroxy fatty acid phosphatase; dihydroxy fatty acid phosphatase; hydroxy lipid phosphatase; sEH (ambiguous); soluble epoxide hydrolase (ambiguous). Enzyme Commission Number: EC 3.1.3.76. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3681; lipid-phosphate phosphatase; EC 3.1.3.76; hydroxy fatty acid phosphatase; dihydroxy fatty acid phosphatase; hydroxy lipid phosphatase; sEH (ambiguous); soluble epoxide hydrolase (ambiguous). Cat No: EXWM-3681. | |
| Native T4-infected Escherichia coli Polynucleotide Kinase | Polynucleotide kinase catalyses a "forward reaction" transfer of the γ-phosphate of ATP to the 5' hydroxyl terminus of single-and double-stranded nucleic acids (DNA and RNA) and 3'-nucleoside monophosphates. In exchange reactions containing ADP, the enzyme will catalyze the exchange of 5'-terminal phosphate groups and ATP. The 3'-phosphatase activity enables the enzyme to remove 3'-phosphoryl groups from phosphorylpolynucleotides. Applications: Suitable for: o sequencing or nucleic acid tagging (dna and rna) by 5?-end labeling o 5? phosphorylation of oligonucleotides o removal of 3?-phosphate groups from phosphorylpolynucleotides. Group: Enzymes. Synonyms: polynucleotide 5'-hydroxyl-kinase; EC 2.7.1.78; 37211-65-7; ATP:5'-dephosphopolynu. Enzyme Commission Number: EC 2.7.1.78. CAS No. 37211-65-7. PNK. Mole weight: mol wt 33 kDa. Activity: 10 units/μL. Storage: -20°C. Form: buffered aqueous glycerol solution. Source: T4-infected Escherichia coli. polynucleotide 5'-hydroxyl-kinase; EC 2.7.1.78; 37211-65-7; ATP:5'-dephosphopolynucleotide 5'-phosphatase; PNK; polynucleotide 5'-hydroxyl kinase (phosphorylating); 5'-hydroxyl polynucleotide kinase; 5'-hydroxyl polyribonucleotide kinase; 5'-hydroxyl RNA kinase; DNA 5'-hydroxyl kinase; DNA kinase; polynucleotide kinase; polynucleotide 5'-hydroxy-kinase. Cat No: NATE-0605. | |
| Novobiocin | Novobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the interaction of both p23 and Hsp70 co-chaperones with the Hsp90 complex. (IC50=700μmol/L). Synonyms: Streptonivicin; Inamycin; Albamycin; Cathomycin; Cardelmycin; Spheromycin; Antibiotic PA-93; Novobiocina; Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-. Grades: >95%. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.62. | |
| Ochratoxin A | Ochratoxin A is a chlorinated benzopyran coupled to the amino acid phenylalanine, produced by several Aspergillus and Penicillium sp. associated with food spoilage. Ochratoxins are widely distributed in the environment and are known to be nephrotoxic, teratogenic and possibly carcinogenic. Ochratoxin A may act by induction of DNA strand breaks, sister chromatid exchanges, DNA adduct formation, or reactive oxygen but the mechanism of action as a toxin is not yet resolved. At the molecular level, ochratoxin A has been shown to specifically inhibit NK cell activity, increase growth of transplantable tumor cells in mice, increase apoptosis, activate c-Jun N terminal kinase in human kidney epithelial cells, and block metaphase/anaphase transition. It also inhibits plasminogen activator inhibitor-2 production by human blood mononuclear cells. Source:Aspergillus ochraceus MST-FP2005. Group: Biochemicals. Alternative Names: OTA; Ochratoxin A; Aspergillus ochraceus; N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine; (-)-N-[(5-Chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl]-3-phenylalanine; (R)-N-[(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-benzo[c]pyran-7-yl)carbon. Grades: Highly Purified. CAS No. 303-47-9. Pack Sizes: 1mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 403.8. US Biological Life Sciences. | Worldwide |
| Pam3CSK4 Biotin | Pam3CSK4 Biotin is the biotinylated Pam3CSK4. Pam3CSK4 is a synthetic tripalmitoylated lipopeptide that mimicks the acylated amino terminus of bacterial lipoproteins. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-κB and a toll-like receptor 1/2 (TLR1/2) agonist. It stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells, and promotes differentiation of naive CD4+ T cells into Th17 cells. Synonyms: (2S, 3Z, 5S, 6Z, 8S, 9Z, 11S, 12Z, 14S, 15Z, 17R)-5, 8, 11-tris(4-aminobutyl)-4, 7, 10, 13, 16-pentahydroxy-2-(4-((Z)-(1-hydroxy-6-((Z)-(1-hydroxy-6-((Z)-(1-hydroxy-5-((3aR, 6S, 6aS)-2-hydroxy-3a, 4, 6, 6a-tetrahydro-1H-thieno[3, 4-d]imidazol-6-yl)pentylidene)amino)hexylidene); Pam3CysSerLys4. Grades: ≥95%. CAS No. 1429504-10-8. Molecular formula: C103H192N14O17S2. Mole weight: 1962.85. | |
| Pentachlorophenol | Used as insecticide for terminate control; pre-harvest defoliant; general herbicide. Antimicrobial preservative and fungicide for wood, wood products, starches, textiles, paints, adhesives, leather, pulp, paper, industrial waste systems, building materials. Surface disinfectant. Group: Biochemicals. Alternative Names: 1-Hydroxy-2,3,4,5,6-pentachlorobenzene; 1-Hydroxypentachloro Benzene ; 2,3,4,5,6-Pentachlorophenol; Chlon; Chlorophenasic Acid; Dowicide 7; Dowicide EC 7; Dura Treet II; EP 30; EP 30 (pesticide); Fungifen; Grundier Arbezol; Lauxtol; Liroprem; NSC 263497; PCP; PCP (pesticide); PKhF; Penchlorol; Penta; Penton 70; Pentor 70; Perchlorophenol; Permasan; Pol Nu; Preventol P; Santophen 20; Satophen; Witophen P; Woodtreat A. Grades: Highly Purified. CAS No. 87-86-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Phomopsin A | Phomopsin A is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids linked in an "ansa" macrocycle with a three amino acid "tail", terminating in a dicarboxylic acid. Phomopsin A is a potent mycotoxin produced by the fungus Phomopsis leptostromiformis and is the causative agent of lupinosis in livestock fed infected lupins. Phomopsin A is an important bioprobe for understanding cellular structural proteins. It acts by selectively binding to dimeric tubulin, inhibiting the formation of the microtubule spindle to block cell division. Phomopsin A binds to tubulin at a site overlapping that of vinblastine and maytansine. Uniquely, phomopsin A protects tubulin from decay. Group: Biochemicals. Alternative Names: 2-Oxa-5, 8-diazabicyclo[10. 3. 1]hexadecane, cyclic peptide deriv.; 3-Chloro-erythro- β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(E)-2,3-didehydroisoleucyl-(E)-2,3-didehydroaspartic acid cyclic (15?3)-ether; NSC 381839. Grades: Highly Purified. CAS No. 64925-80-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Poly(dimethylsiloxane-co-diphenylsiloxane), divinyl terminated | 84:16 mole ratio of dimethylsiloxane:diphenylsiloxane. Group: Bioelectronic materials self assembly and lithography. CAS No. 68951-96-2. Pack Sizes: 25 mL in poly bottle. Product ID: dimethyl(oxo)silane; ethenyl-hydroxy-dimethylsilane; oxo(diphenyl)silane. Molecular formula: 374.7g/mol. Mole weight: C18H26O3Si3. C[Si](C)=O. C[Si](C)(O)C=C. O=[Si](c1ccccc1)c2ccccc2. InChI=1S/C12H10OSi. C4H10OSi. C2H6OSi/c13-14 (11-7-3-1-4-8-11)12-9-5-2-6-10-12; 1-4-6 (2, 3)5; 1-4 (2)3/h1-10H; 4-5H, 1H2, 2-3H3; 1-2H3. NXTBQQSLKSMQNL-UHFFFAOYSA-N. | |
| PyOxim | PyOxim is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Synonyms: pyoxime; AS-10531; SC-13336; CS-0068035; K-4853; J-009012; (Ethyl cyano(hydroxyimino)acetato)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate; [cyano- (ethoxycarbonyl) methyleneaminooxy]tris (1-pyrrolidinyl) phosphonium hexafluorophosphate; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)?-[ethyl 2-cyano-2-[(hydroxy-κO)?imino]?acetato]?tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(?1-). Grades: > 98% (HPLC). CAS No. 153433-21-7. Molecular formula: C17H29F6N5O3P2. Mole weight: 527.38. | |
| VH 032-linker 6 | VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75. | |
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