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| Product | Description | |
|---|---|---|
| ICA | ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC 50 of 2.1 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine. CAS No. 3374-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-22044. |  |
| ICA 069673 | ICA 069673. Group: Biochemicals. Grades: Purified. CAS No. 582323-16-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ICA-069673 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ICA-069673 | ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Synonyms: ICA 069673; ICA069673. CAS No. 582323-16-8. Molecular formula: C11H6ClF2N3O. Mole weight: 269.63. |  |
| ICA 110381 | ICA 110381. Group: Biochemicals. Grades: Purified. CAS No. 325457-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICA 110381 | ICA 110381 is a KV7.2/7.3 activator with EC50 value of 0.38 μM. It has anticonvulsive properties in amygdala-kindled rat. It selectively activates human KCNQ2 expressed in Chinese hamster ovary and may be used to study the pharmacological activities. It also decreases neuronal excitability in CA1 hippocampal neurons. Synonyms: ICA 110381; ICA110381; ICA-110381; 4-Chloro-N-(6-chloro-3-pyridinyl)benzamide. Grades: ≥98% by HPLC. CAS No. 325457-99-6. Molecular formula: C12H8Cl2N2O. Mole weight: 267.11. | |
| ICA 121431 | ICA 121431. Group: Biochemicals. Grades: Purified. CAS No. 313254-51-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICA-121431 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ICA-121431 | ICA-121431 is a potent and selective inhibitor of human NaV1.3 (IC50=13 nM) and NaV1.1 channels (IC50=23 nM) with 1,000 fold selectivity against other resistant sodium channels like human Nav1.5 or Nav1.7 channels. Synonyms: ICA-121431; ICA 121431; ICA121431. 2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide2,2-diphenyl-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)acetamideICA-121431; ICA 121431; ICA121431. CAS No. 313254-51-2. Molecular formula: C23H19N3O3S2. Mole weight: 449.54. | |
| ICA-27243 | ICA-27243 is a selective, effective and orally active KCNQ2/Q3 potassium channel opener with EC50 of 0.38 μM. Synonyms: Benzamide, N-(6-Chloro-3-Pyridinyl)-3,4-Difluoro-. Grades: 98%. CAS No. 325457-89-4. Molecular formula: C12H7ClF2N2O. Mole weight: 268.64. | |
| ICAM-1-IN-1 | ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC 50 values of 7 and 5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 251994-14-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00003. | |
| ICAM2 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| ICAM-I human | recombinant, expressed in CHO cells, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Icanbelimod | Icanbelimod (S1p receptor agonist 1) is a potent and orally active S1P receptor agonist, exhibits an activity of inducing S1P1 internalization (EC50=9.83 nM). Icanbelimod has the potential for the study of arthritis and EAE (experimental autoimmune encephalitis). Icanbelimod is extracted from patent WO2015039587A1, Compound 2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1p receptor agonist 1. CAS No. 1514888-56-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101265. | |
| Icapamespib | Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ151 and radiolabeled PU-HZ151 showed selectivity for epichaperomes over the individual chaperome members. Icapamespib demonstrated the ability to productively engage the target in cells, mice, and humans. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Icapamespib; PU-HZ 151; PU-HZ-151; PU-HZ151; PUHZ 151; PUHZ-151; PUHZ151. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1000999-96-1. Molecular formula: C19H23IN6O2S. Mole weight: 526.4. Purity: >98%. IUPACName: 9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine. Canonical SMILES: NC1=C2N=C(SC3=C(I)C=C(OCO4)C4=C3)N(CCNCC(C)(C)C)C2=NC=N1. Product ID: ACM1000999961. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Icariin | 7-(β-D-Glucopyranosyloxy)-5-hydroxy-4-methoxy-8-(3-methylbut-2-en-1-yl)-3-(α-L-rhamnopyranosyloxy)flavone C33H40O15. CAS No. 489-32-7. Product ID: 8-05151. Mole weight: 676.67. Properties: Prenylated flavonol glycoside. |  |
| Icariin | Icariin. Group: Biochemicals. Grades: Plant Grade. CAS No. 489-32-7. Pack Sizes: 20mg. Molecular Formula: C33H40O15, Molecular Weight: 676.66. US Biological Life Sciences. | Worldwide |
| Icariin | Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Synonyms: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-b-D-glucopyranosyloxy-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. Grades: ≥ 98%. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66. | |
| Icariin | Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66. Purity: 0.98. IUPACName: 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one. Canonical SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O. Density: 1.55 g/ml. Product ID: ACM489327. Alfa Chemistry ISO 9001:2015 Certified. | |
| Icariin | Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC 50 s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Uses: Scientific research. Group: Natural products. Alternative Names: Ieariline. CAS No. 489-32-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0014. | |
| Icariin | Icariin - Product ID: NST-10-63. Category: Flavonoids. Purity: 98%. Test method: HPLC. CAS No. 489-32-7. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: Yellow Powder. Molecular formula: C33H40O15. Mole weight: 676.66. Storage: +2 +8 °C. |  |
| Icariside I | Icariside I. Group: Biochemicals. Grades: Plant Grade. CAS No. 56725-99-6. Pack Sizes: 10mg. Molecular Formula: C27H30O11, Molecular Weight: 530.52. US Biological Life Sciences. | Worldwide |
| Icariside I | Icariside I Inhibitor. Uses: Scientific use. Product Category: T3808. CAS No. 56725-99-6. |  |
| Icariside I | Icariside I is extracted from the herbs of Epimedium brevicornum Maxim. Synonyms: Icariin I. Grades: >98%. CAS No. 56725-99-6. Molecular formula: C27H30O11. Mole weight: 530.5. | |
| Icaritin | Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornu Maxim. and potently inhibits proliferation of K562 cells ( IC 50 of 8 μM) and primary CML cells ( IC 50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [1] [2] [3. Uses: Scientific research. Group: Natural products. Alternative Names: Anhydroicaritin. CAS No. 118525-40-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0678. | |
| Icaritin | Icaritin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 118525-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H20O6. US Biological Life Sciences. | Worldwide |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or time-dependent manner. Synonyms: Anhydroicaritin; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 3-hydroxy-7-o-beta-glucose-8-prenyl-4''-methoxy Chrysin. Grades: >98%. CAS No. 118525-40-9. Molecular formula: C21H20O6. Mole weight: 368.38. | |
| Icaritin | Icaritin - Product ID: NST-10-167. Category: Flavonoids. Purity: 98%. Test method: HPLC. CAS No. 118525-40-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White Powder. Molecular formula: C21H20O6. Mole weight: 368.38. Storage: +2 +8 °C. | |
| Icaritin (Anhydroicaritin) | Icaritin (Anhydroicaritin). Group: Biochemicals. Grades: Plant Grade. CAS No. 118525-40-9. Pack Sizes: 20mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences. | Worldwide |
| Icaritin Liposome (PEGylated) | Icaritin is a natural flavonoid compound that exhibits anticancer effects on various tumors, including hematologic malignancies such as leukemia, lymphoma, and multiple myeloma. This product is a pre-formulated liposome encapsulating Icaritin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Icatibant | Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC 50 and K i of 1.07 nM and 0.798 nM respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: HOE 140. CAS No. 130308-48-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-17446. | |
| Icatibant | Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-; H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; HOE140; HOE 140; HOE-140. Grades: >98%. CAS No. 130308-48-4. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| Icatibant acetate | Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC 50 and K i of 1.07 nM and 0.798 nM respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: HOE 140 acetate. CAS No. 138614-30-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108896. | |
| Icatibant Acetate | Icatibant Acetate. Categories: icatibant acetate; hoe-140. |  CA, FL & NJ |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grades: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
| (1-6)-Icatibant | (1-6)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanine; D-Arg-Arg-Pro-Hyp-Gly-Thi-OH. CAS No. 2698340-93-9. Molecular formula: C31H50N12O8S. Mole weight: 750.88. | |
| 2"-O-rhamnosyl icariside II | 2"-O-rhamnosyl icariside II. Group: Biochemicals. Grades: Plant Grade. CAS No. 135293-13-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 4-Thiazolecarboxyl icacid, 2- (amino methyl ) -, ethyl ester (9CI) | 4-Thiazolecarboxyl icacid, 2- (amino methyl ) -, ethyl ester (9CI) . Group: Biochemicals. Grades: Highly Purified. CAS No. 91711-96-5. Pack Sizes: 10g, 25g. US Biological Life Sciences. | Worldwide |
| (7-10)-Icatibant | (7-10)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-3-Carbonyl-L-octahydroindole-2-carboxamido-L-arginine; H-Ser-D-Tic-Oic-Arg-OH; L-Arginine, L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-; ((2S,3aS,7aS)-1-((R)-2-(L-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1H-indole-2-carbonyl)-L-arginine. CAS No. 148416-85-7. Molecular formula: C28H41N7O6. Mole weight: 571.68. | |
| 8-Quinolinecarboxyl icacid | 8-Quinolinecarboxyl icacid. Group: Biochemicals. Grades: Highly Purified. CAS No. 86-59-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H7NO2. US Biological Life Sciences. | Worldwide |
| Ac-Icatibant | Ac-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: Ac-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; Acetyl-D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; L-Arginine, N2-acetyl-D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-65-4. Molecular formula: C61H91N19O14S. Mole weight: 1346.58. | |
| Anhydroicaritin | β-Anhydroicaritin is an Icartin (I163680) derivative displaying anti-inflammatory activity and inhibition of human phosphodiesterase-5. Synonyms: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one. Grades: >98%. CAS No. 38226-86-7. Molecular formula: C21H20O6. Mole weight: 368.4. | |
| Anti-phospho-ICAM-1 (pTyr512) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-ICAM1 (pTyr512) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Baohuoside I (Anhydroicaritin, Icariside II) | Baohuoside I (Anhydroicaritin, Icariside II). Group: Biochemicals. Alternative Names: Icariside II. Grades: Plant Grade. CAS No. 113558-15-9. Pack Sizes: 20mg. Molecular Formula: C27H30O10, Molecular Weight: 514.520999999999. US Biological Life Sciences. | Worldwide |
| Des-D-Arg(1)-Icatibant | Des-D-Arg(1)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-Arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; Bradykinin, 3-(trans-4-hydroxy-L-proline)-5-[3-(2-thienyl)-L-alanine]-7-(D-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid)-8-[(2α,3aβ,7aβ)-L-octahydro-1H-indole-2-carboxylic acid]-. CAS No. 130334-60-0. Molecular formula: C53H77N15O12S. Mole weight: 1148.35. | |
| Des-L-Arg(2)-Icatibant | Des-L-Arg(2)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: D-Arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; D-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; L-Arginine, D-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193740-38-4. Molecular formula: C53H77N15O12S. Mole weight: 1148.35. | |
| Desmethyl Icaritin | A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone; 4'-Desmethylicaritin; 8-Prenylkaempferol; De-O-methylanhydroicaritin; Noranhydroicaritin. Grades: Highly Purified. CAS No. 28610-31-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desmethyl Icaritin Tri-O-methoxymethyl Ether | Protected Icaritin metabolite. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone Tri-O-methoxymethyl Ether; 4'-Desmethylicaritin Tri-O-methoxymethyl Ether; 8-Prenylkaempferol Tri-O-methoxymethyl Ether; De-O-methylanhydroicaritin Tri-O-methoxymethyl Ether; Noranhydroicaritin Tri-O-methoxymethyl Ether. Grades: Highly Purified. CAS No. 143724-76-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Horny Goat Weed P.E. 10% Icariins HPLC | Horny Goat Weed P.E. 10% Icariins HPLC. | CA, FL & NJ |
| L-Arg(1)-Icatibant | L-Arg(1)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; L-Arginine, L-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-59-6. Molecular formula: C59H89N19O13S. Mole weight: 1304.54. | |
| Monoclonal Anti-ICAM1 antibody produced in mouse | clone 3H8-2G6, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-ICAM3 antibody produced in mouse | clone 2F8, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Picaridin | Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Insect repellent. Picaridin is an insect repellent that is effective against a range of arthropods, including mosquitoes and ticks.1,2 It shows synergy with the non-pyrethroid insecticide propoxur both in killing and repelling mosquitoes.3 Picaridin and other insect repellents have been shown to act as either agonists or antagonists at insect olfactory receptors.4,5. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-propyl Ester; Icaridin; KBR 3023; Bayrepel. Grades: Highly Purified. CAS No. 119515-38-7. Pack Sizes: 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Picaridin | Picaridin,also known as Icaridin, KBR 3023, under the INCI name hydroxyethyl isobutyl piperidine carboxylate, and the trade names Bayrepel and Saltidin, is an insect repellent that is effective against a range of arthropods, including mosquitoes and ticks. Uses: Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources; insect repellent. Synonyms: KBR 3023; KBR-3023; KBR3023. ICARIDIN;1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine;1-(1-methylpropoxycarbonyl)-2-(2-hydroxyethyl)piperidine;1-methylpropyl2-(2-hydroxyethyl)-1-piperidinecarboxylate;2-(2-hydroxyethyl)-1-piperidinecarboxylicaci1-methylpropylester. Grades: 98%. CAS No. 119515-38-7. Molecular formula: C12H23NO3. Mole weight: 229.32. | |
| Picaridin-d3 | Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-d3-propyl Ester; Icaridin-d3; KBR 3023-d3; Bayrepel-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide) | PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide). Group: Biochemicals. Alternative Names: N'-phenylpyridine-4-carbohydrazide. Grades: Highly Purified. CAS No. 91396-88-2. Pack Sizes: 50mg. Molecular Formula: C12 H11 N3, Molecular Weight: 213.2. US Biological Life Sciences. | Worldwide |
| Senicapoc | Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694. | |
| Senicapoc | Senicapoc, previously called as ICA 17043, is a small organic potent and selective blocker of the Gardos channel which is the calcium-activated potassium channel located on the human RBC, inhibiting the efflux of K+ through this channel. Synonyms: 2,2-bis(4-fluorophenyl)-2-phenylacetamide; bis(4-fluorophenyl)phenylacetamide; ICA 17043; ICA-17043; ICA17043. CAS No. 289656-45-7. Molecular formula: C20H15F2NO. Mole weight: 323.34. | |
| 5-O-(3-Methyl-2-butenyl) Kaempferol Tri-O-methoxymethyl Ether | Intermediate in the preparation of Icaritin metabolites. Group: Biochemicals. Alternative Names: 3, 7-Bis (methoxymethoxy) -2-[4- (methoxymethoxy) phenyl]-5-[ (3-methyl-2-butenyl) oxy]-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 143724-70-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7α-Hydroxy Cholesterol | 7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid and chenodeoxycholic acid. 7α-Hydroxy Cholesterol is also a secondary metabolite of Cholesterol. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). Synonyms: cholest-5-ene-3β,7α-diol; 7alpha-hydroxy-cholesterol; 7-alpha-OHC. Grades: > 95%. CAS No. 566-26-7. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| A-205804 | A-205804 is a potent, selective and orally bioavailable lead inhibitor of E-selectin and ICAM-1 expression, with IC50s of 20 and 25 nM for E-selectin and ICAM-1, respectively. It can be used in the study of chronic inflammatory diseases. Synonyms: 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide; 4-[(4-methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide; 4-(p-Tolylsulfanyl)thieno[2,3-c]pyridine-2-carboxamide. Grades: >98%. CAS No. 251992-66-2. Molecular formula: C15H12N2OS2. Mole weight: 300.40. | |
| ABH hydrochloride | ABH (hydrochloride) is an orally active arginase inhibitor ( K i = 8.5 nM). ABH hydrochloride promotes NO production and reduces the expression of inflammatory response-related molecules ( ICAM-1 , VCAM-1 , MCP-1 ). ABH hydrochloride improves erectile function, reduces lung damage, promotes wound healing, reduces arterial blood pressure, and improves vascular fibrosis [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. CAS No. 194656-75-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112868B. | |
| Adxanthromycin A | Adxanthromycin A, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C42H40O17. Mole weight: 816.76. | |
| Adxanthromycin B | Adxanthromycin B, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C48H50O22. Mole weight: 978.90. | |
| AITRL human | AITRL, a cytokine belonging to the tumor necrosis factor (TNF) ligand superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. AITRL is a ligand for receptor TNFRSF18/AITR/GITR. GITR/AITRL interaction plays a role in the pathogenesis of tumors, inflammation, and autoimmune diseases. In addition, AITRL is involved in endothelial cell (EC) activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1). Synonyms: Activation-induced TNFR member Ligand; TNFSF18; rHuActivation-inducible TNF-related Ligand/AITRL; GITRL; TL-6; Tumor necrosis factor ligand superfamily member 18; rHuAITRL; GITR Ligand. Grades: ≥98% by HPLC. Mole weight: ~14.3 kDa. | |
| Andrographolide | Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent. Group: Biochemicals. Alternative Names: (3E, 4S) -3- [2- [ (1R, 4aS, 5R, 6R, 8aS) -Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; [1R-[1α[E(S*)],4a β , 5α , 6α , 8aα ] ] -3- [2- [Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; 3α,14,15,18-Tetrahydroxy-5 β,9 βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone; Andrographis; Andrographolid. Grades: Highly Purified. CAS No. 5508-58-7. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Anisodamine | Anisodamine, an anticholinergic drug, has antishock effect, which is intimately linked to alpha7nAChR-dependent anti-inflammatory pathway. Anisodamine demonstrates a direct cardiac depressive action at the myocyte level, which may be related to, at least in part, NO production and cholinoceptor antagonism, it causes the changes of structure and function in the transmembrane domain of the Ca(2+)-ATPase from sarcoplasmic reticulum. Anisodamine, a vasoactive drug, can abate endogenous endotoxaemia subsequent to splanchnic vasoconstriction due to hypovolaemia, it alleviates inflammatory damage by significantly reducing the expressions of VEGF and ICAM-1, and shows significant protective effects in an animal model of infusion phlebitis. Anisodamine also inhibits shiga toxin type 2-mediated tumor necrosis factor-alpha production in vitro and in vivo. Group: Biochemicals. Grades: Plant Grade. CAS No. 55869-99-3. Pack Sizes: 100mg. Molecular Formula: C17H23NO4, Molecular Weight: 305.374. US Biological Life Sciences. | Worldwide |
| Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human) | Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: INTERCELLULAR ADHESION MOLECULE 1 (1-23);ICAM 1 (1-23);H-ASN-ALA-GLN-THR-SER-VAL-SER-PRO-SER-LYS-VAL-ILE-LEU-PRO-ARG-GLY-GLY-SER-VAL-LEU-VAL-THR-CYS-OH;ASN-ALA-GLN-THR-SER-VAL-SER-PRO-SER-LYS-VAL-ILE-LEU-PRO-ARG-GLY-GLY-SER-VAL-LEU-VAL-THR-CYS;ASN-ALA-IC. Product Category: Heterocyclic Organic Compound. CAS No. 139227-42-2. Molecular formula: C99H173N29O32S. Mole weight: 2313.67. Product ID: ACM139227422. Alfa Chemistry ISO 9001:2015 Certified. | |
| Baohuoside I | Baohuoside I - Product ID: NST-10-150. Category: Flavonoids. Alternative Names: Icariin II, Icariside II. Purity: 98%. Test method: HPLC. CAS No. 113558-15-9. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige colored Powder. Molecular formula: C27H30O10. Mole weight: 514.52. Storage: +2 +8 °C. | |
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