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| Product | Description | |
|---|---|---|
| LE 135 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| LE 135 | LE 135. Group: Biochemicals. Alternative Names: 4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic Acid; 5H-Benzo[e]naphtho[2,3-b][1,4]diazepine Benzoic Acid Deriv. Grades: Highly Purified. CAS No. 155877-83-1. Pack Sizes: 5mg. Molecular Formula: C29H30N2O2, Molecular Weight: 438.56. US Biological Life Sciences. |  Worldwide |
| LE 135 | LE 135 is a retinoic acid antagonist which shows moderate selectivity for RARβ over RAR&alpha. It can inhibit human HL-60 leukemia cell differentiation induced by Am80 with IC50 value of 150 nM. Synonyms: LE135; LE-135; 4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid; Benzoic acid, 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)-. Grades: ≥97% by HPLC. CAS No. 155877-83-1. Molecular formula: C29H30N2O2. Mole weight: 438.56. |  |
| 1,6-Anhydro-beta-D-glucopyranose (Levoglucosan) | 1g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C6H10O5. CAS No. 498-07-7. Prepack ID 13585366-1g. Molecular Weight 162.14. See USA prepack pricing. |  |
| (16 β)-17,21-Dihydroxy-16 β-methyl-pregna-1,4,9(11)-triene-3,20-dione | (16 β)-17,21-Dihydroxy-16 β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient. Group: Biochemicals. Grades: Highly Purified. CAS No. 13504-15-9. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C22H28O4. US Biological Life Sciences. | Worldwide |
| 1-Hydroxybenzotriazole anhydrous | HOBT. additive for oligonucleotide couplings and in racemization-free peptide couplings. CAS No. 2592-95-2. Product ID: 1-01590. Molecular formula: C6H5N3O. Mole weight: 135.13. Purity: >99%. Source : Reference: Tetrahedron Lett., 35, 3315, 1994; Synlett. 733, 1993; Int. J. Peptide Protein Res., 42, 264, 1993. |  |
| 1-Hydroxybenzotriazole hydrate | HOBT wetted with ≥14 wt. % water. additive for oligonucleotide couplings and in racemization-free peptide couplings. CAS No. 123333-53-9. Product ID: 1-01597. Molecular formula: C6H5N3O xH2O. Mole weight: 135.13. Reference: Tetrahedron Lett., 35, 3315, 1994; Synlett. 733, 1993; Int. J. Peptide Protein Res., 42, 264, 1993. | |
| 2,2'-Dodecylidenebis-1H-phenalene-1,3(2H)-dione | 2,2'-Dodecylidenebis-1H-phenalene-1,3(2H)-dione is an intermediate in the synthesis of Tribenzo[de, h, kl]naphtho[1, 2, 3, 4-rst]pentaphene (T767600), which is used in nanotechnology in the the optical sensing of current dynamics in LED devices. Group: Biochemicals. Grades: Highly Purified. CAS No. 1357481-39-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C38H38O4. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carbonitrile | Intermediate for the preparation of medicines and agrochemicals. Group: Biochemicals. Alternative Names: 2,4-Diamino-5-cyanopyrimidine; 2, 4-Diamino-5-pyrimidinecarbonitri le; NSC 135235. Grades: Highly Purified. CAS No. 16462-27-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-Benzoxazolinone | 2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts. Derivatives as anti-quorum sensing agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,3-Dihydro-2-oxo-1,3-benzoxazole. Product Category: Inhibitors. Appearance: Solid. CAS No. 59-49-4. Molecular formula: C7H5NO2. Mole weight: 135.12. Purity: 95%+. Canonical SMILES: O=C1OC2=CC=CC=C2N1. Product ID: ACM59494-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-beta-D-arabinouridine | 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-beta-D-arabinouridine, a nucleoside analogue with immense potential, has been leveraged to tackle malignant hematologic and solid tumors. Its action initiates with the disruption of cancer cell DNA synthesis, curbing their exuberance and metastasis. Clinical trials have hinted at its efficaciousness in suppressing the growth of leukemia, lymphoma and pancreatic carcinomas, inducing a ray of hope for patients suffering from these ailments. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-5-methyl-; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 135123-34-1. Molecular formula: C10H13FN2O4S. Mole weight: 276.28. | |
| 2-Fluorobenzyl Cyanide | 2-Fluorobenzyl Cyanide. Group: Biochemicals. Alternative Names: (o-Fluorophenyl) acetonitrile; (2-Fluorophenyl) acetonitrile; 2- (2-Fluorophenyl) acetonitrile; 2-Fluoro Benzene acetonitrile; 2-Fluorobenzylnitrile; NSC 88280; o-Fluorobenzyl Cyanide; o-Fluorobenzyl Nitrile; o-Fluorophenylacetonitri le. Grades: Highly Purified. CAS No. 326-62-5. Pack Sizes: 5g. Molecular Formula: C8H6FN, Molecular Weight: 135.139999999999. US Biological Life Sciences. | Worldwide |
| 2-Isopropylpyridin-4-yl-boronic Acid Pinacol Ester | 2-Isopropylpyridin-4-yl-boronic Acid Pinacol Ester is used in preparation of thioacetate compounds as URAT-1 agonists useful in the treatment of diseases assocd. with aberrant levels of uric acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1352796-58-7. Pack Sizes: 250mg, 2.5g. Molecular Formula: C14H22BNO2, Molecular Weight: 247.14. US Biological Life Sciences. | Worldwide |
| 4-Chloro-2-propylsulfanyl-pyrimidine | An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: Pyrimidine, 4-chloro-2-(propylthio)-. CAS No. 1351990-36-7. Molecular formula: C7H9ClN2S. Mole weight: 188.673. | |
| 6-Aminopruine | 6-Aminopruine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: adensoine; 9H-purin-6-amine; ADENINE(P); 1H-Purin-6-amine; 7(9)H-purin-6-ylamine; Ade; Adenin; usafcb-18; Leuco-4; Adenine; Crytidine; Vitamin B4; 6-aminopurine. Product Category: Heterocyclic Organic Compound. Appearance: white to off-white crystalline powder. CAS No. 73-24-2. Molecular formula: C5H5N5. Mole weight: 135.127. Purity: 0.96. IUPACName: adenine. Density: 1.612 g/cm³. Product ID: ACM73242. Alfa Chemistry ISO 9001:2015 Certified. | |
| 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride | 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine is an inhibitor of fusion protein interaction of menin-mixed lineage leukemia (menin-MLL). Menin-MLL inhibitors downregulate the expression of target genes required for MLL fusion protein oncogenic activity and thus effectively reverse MLL fusion protein-mediated leukemic transformation. Group: Biochemicals. Alternative Names: 4-(4-(1,3,4-Thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidine Hydrochloride; MI-nc (hydrochloride). Grades: Highly Purified. CAS No. 1359873-45-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ac2-12 | Ac2-12 is an annexin/lipocortin 1-mimetic peptide that inhibits leukocyte extravasation. It promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo. It reduces neutrophil adhesion and emigration. It has an anti-inflammatory effect. Synonyms: LPC1; ANX1; ANXA-1. CAS No. 256447-08-2. Molecular formula: C63H94N14O17S. Mole weight: 1351.58. | |
| Acibenzolar-S-methyl | Acibenzolar-S-methyl (ASM) is a plant resistance inducer that mimics pathogen-host interactions and leads to systemic acquired resistance in plants. Acibenzolar-S-methyl helps reduce the use of pesticides and can be used in research to prevent plant diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASM. CAS No. 135158-54-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116541. |  |
| Adenine hydrochloride (1:x) | Adenine HCl is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. Synonyms: Adenine hydrochloride; 2922-28-3; 6-Aminopurine hydrochloride; 7H-purin-6-amine hydrochloride; ADENINE HCL; Adenine monohydrochloride; 1H-Purin-6-amine, monohydrochloride; 9H-Purin-6-amine, hydrochloride (1:1); Leucon; Adenine (hydrochloride); 22177-51-1; 1H-Purin-6-amine, hydrochloride; CHEMBL539503; 7H-purin-6-amine; hydrochloride; 9H-purin-6-amine hydrochloride; 364H11M7OD; MFCD00075782; 6-Aminopurine (hydrochloride); Vitamin B4 (hydrochloride); Adeninehydrochloride; 1H-Adenine hydrochloride; UNII-364H11M7OD; 1h-purin-6-amine monohydrochloride. CAS No. 22177-51-1. Molecular formula: C5H5N5.xHCl. Mole weight: 135.128 (free base). | |
| AR-R17779 hydrochloride | AR-R17779 hydrochloride is a potent and selective full agonist of nAChR , with K i s of 92 and 16000 nM for α7 and α4β2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178419-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135483A. | |
| Atizoram | Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-80,633. CAS No. 135637-46-6. Pack Sizes: 500 μg. Product ID: HY-108623. | |
| Azoxymethane | Azoxymethane is a colon carcinogen which leads to the formation of DNA adducts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AOM. CAS No. 25843-45-2. Pack Sizes: 5 mg (135 mM * 500 μL in Water); 10 mg (135 mM * 1 mL in Water); 25 mg (135 mM * 2.5 mL in Water); 50 mg (135 mM * 5 mL in Water); 100 mg (135 mM * 10 mL in Water). Product ID: HY-111375. | |
| Batabulin sodium | Batabulin sodium (T138067 sodium) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes , thereby disrupting microtubule polymerization. Batabulin sodium affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T138067 sodium. CAS No. 195533-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13563A. | |
| b-D-Maltose octaacetate | b-D-Maltose octaacetate is a chemical compound widely used in the compound industry. It is primarily utilized as a precursor for various pharmaceutical drugs, particularly in the research of diabetes and cardiovascular diseases. This compound plays a crucial role in the research and development of therapeutic agents aimed at controlling blood sugar levels and improving heart health. Synonyms: Octa-O-acetyl-b-D-maltose; Octaacetyl maltose; β-D-Glucopyranose, 4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-, 1,2,3,6-tetraacetate; 4-O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranose tetraacetate; NSC 1351. Grades: ≥98%. CAS No. 22352-19-8. Molecular formula: C28H38O19. Mole weight: 678.59. | |
| BE-10988 | BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (μmol/L) of 0.5, 0.4, 2.0, respectively. CAS No. 135261-89-1. Molecular formula: C13H10N4O3S. Mole weight: 302.31. | |
| Belizatinib | Belizatinib is inhibitor of both anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases (TRK). Belizatinib can bind to and inhibit both ALK and TRK kinases and this inhibition can lead to the disruption of ALK- and TRK-mediated signaling and impede tumor cell growth in ALK/TRK-overexpressing tumor cells. Phase I/II clinical trials for Lymphoma, Non-small cell lung cancer and Solid tumours is on-going. Uses: Lymphoma; non-small cell lung cancer; solid tumours. Synonyms: TSR011; TSR011; TSR 011; Belizatinib;4-fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-((1s,4s)-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide. Grades: 98%. CAS No. 1357920-84-3. Molecular formula: C33H44FN5O3. Mole weight: 577.75. | |
| Benzyl (2S, 3S, 5S) -2-Hexyl-3-benzyloxy-5- [ [ (S) -2- (formylamino) -4- (methyl-d3) -pentanoyl] oxy] hexadecanoate | Benzyl (2S, 3S, 5S) -2-Hexyl-3-benzyloxy-5- [ [ (S) -2- (formylamino) -4- (methyl-d3) -pentanoyl] oxy] hexadecanoate. Group: Biochemicals. Alternative Names: N-Formyl-L-leucine (1S) -1-[ (2S, 3S) -2- (Phenylmethoxy) -3-[ (phenylmethoxy) carbonyl]nonyl]dodecyl Ester-d3. Grades: Highly Purified. CAS No. 1356931-00-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Betamethasone EP Impurity C | Betamethasone EP Impurity C is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. It is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone. Synonyms: (16beta)-17,21-Dihydroxy-16-Methylpregna-1,4,9(11)-Triene-3,20-Dione; 17,21-dihydroxy-16β-methylpregna-1,4,9(11)-triene-3,20-dione; NSC699834; 16β-Methyl-17,21-dihydroxypregna-1,4,9(11)-triene-3,20-dione. Grades: > 95%. CAS No. 13504-15-9. Molecular formula: C22H28O4. Mole weight: 356.47. | |
| Calcium Pyrophosphate | Calcium Pyrophosphate. Synonyms: ACP. CAS No. 7790-76-3. Pack Sizes: 5 g in poly bottle. Product ID: CDC10-0225. Molecular formula: Ca2O7P2. Category: Buffering Agents. Product Keywords: Cosmetic Ingredients; Buffering Agents; Calcium Pyrophosphate; CDC10-0225; 7790-76-3; Ca2O7P2; ACP; 232-221-5; MFCD00015983; 7790-76-3. Purity: 0.99. Color: White. EC Number: 232-221-5. Physical State: Powder. Quality Level: 100. Melting Point: 1353°C. Density: 3.09 g/cm3. |  |
| CALP2 | CALP2 is a cell-permeable calmodulin (CaM) antagonist binding to the EF-hand/Ca2+-binding site. CALP2 exhibits an inhibitory effect on CaM-dependant phosphodiesterase activity, and leads to an increase on intracellular Ca2+ level by modulating Ca2+-channel activity. CALP2 was also shown to be a potent activator of alveolar macrophages. Synonyms: Calcium-like peptide 2. CAS No. 261969-04-4. Molecular formula: C68H104N14O13S. Mole weight: 1357.72. | |
| Carbon nanotube sheet | Multi-walled carbon nanotubes are aligned in a direction. The CNTs are just connected with van der Waals forces, and no binder material is used. The sheet shows high anisotropic transport properties, including electrical conductivity and thermal conductivity. CNT has a multi-walled structure. Crystal quality of CNT is examined by Raman scattering measurement. Intensity ratio of G-peak (1580 cm-1) and D-peak (1350 cm-1) represents quality of graphitization of carbon materials. G/D of CNT is ?3, showing high crystal quality. The high crystallinity is supported by transmission electron microscopy. Uses: Bioimaging photocatalysis led energy conversion sensing. Group: Carbon nano materials. CAS No. 308068-56-6. |  |
| Cladribine Impurity F | Cladribine Impurity F is an impurity of cladribine, a medication utilized for the therapy of hairy cell leukemia and multiple sclerosis. Synonyms: 4-Methylbenzamide; p-Toluamide. Grades: > 95%. CAS No. 619-55-6. Molecular formula: C8H9NO. Mole weight: 135.16. | |
| CNX-1351 | CNX-1351 is a selective covalent Inhibitor of PI3K&alpha. In an end point assay, CNX-1351 potently inhibited PI3Kα and was 20-400 times less potent against β, γ, and &delta. CNX-1351 inhibit PI3Kα signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3K&alpha. CNX-1351 also inhibits PI3Kα signaling in vivo and bonds to p110&alpha. Synonyms: CNX-1351; CNX 1351; CNX1351. Grades: 0.98. CAS No. 1276105-89-5. Molecular formula: C30H35N7O3S. Mole weight: 573.716. | |
| Coluracetam | Coluracetam (MKC-231) is an orally taken choline uptake enhancer. Coluracetam can improve the reduced acetylcholine levels in the hippocampus of rats and mice, enhancing learning difficulties, memory deficits, and cognitive impairments. Coluracetam induces a lower degree of hepatic venous hyperglycemia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MKC-231. CAS No. 135463-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17553. | |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. Grades: >98%. CAS No. 135463-81-9. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
| CX-6258 Hydrochloride | CX-6258 shows antiproliferative activity against a panel of human cancer cell lines with IC50 of 0.02-3.7 μM, mostly sensitive to acute leukemia cell lines. Synonyms: CX-6258 HCl; CX 6258 hydrochloride; CX 6258 HCl; CX6258 HCl. Grades: >98%. CAS No. 1353859-00-3. Molecular formula: C26H25Cl2N3O3. Mole weight: 498.40. | |
| Echinomycin | It is produced by the strain of Streptomyces echinatus. It has the activity of anti-gram-positive bacteria and vaginal trichomonas, and also has the effect on influenza virus and sarcoma 180 cells in vitro. Synonyms: Quinomycin A; Levomycin; N,N'-((1R,4S,7R,11S,14R,17S,20R,24S)-11,24-diisopropyl-2,4,12,15,17,25-hexamethyl-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-thia-2,5,12,15,18,25-hexaazabicyclo[12.12.3]nonacosane-7,20-diyl)bis(quinoxaline-2-carboxamide); N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl-L-valine-(81)-lactone-cyclic(37)-thioether; Antibiotic A 654I; NSC 13502; NSC 526417. Grades: >99% by HPLC. CAS No. 512-64-1. Molecular formula: C51H64N12O12S2. Mole weight: 1101.25. | |
| Gadoxetate disodium | Gadoxetate (Gd-EOB-DTPA) Disodium is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system, which accumulates in normal, functioning hepatocytes. Gadoxetate Disodium aggravates liver fibrosis (LF) induced gadolinium deposition in the liver and deep cerebellar nuclei (DCN) of rats without significant acute histological alterations. Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or dysplastic nodules [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gd-EOB-DTPA disodium; ZK 139834. CAS No. 135326-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16219. | |
| H-Dl-leu-dl-val-oh h2o | H-Dl-leu-dl-val-oh h2o. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DL-Leucyl-DL-valine, Leu-Val, 35436-83-0, L-Leucyl-L-Valine, 13588-95-9, NSC524458, AC1L6ZLN, H-DL-Leu-DL-Val-OH, AC1Q1P4V, DL-Valine, N-DL-leucyl-, ACMC-1C69U, AGN-PC-01Z70K, CTK8B1523, MolPort-001-813-647, ANW-28201, AKOS009158094, MCULE-9731749811, NSC-524458, L0041, ST50411555. Product Category: Heterocyclic Organic Compound. CAS No. 35436-83-0. Molecular formula: C11H24N2O4. Mole weight: 230.31. Purity: 0.96. IUPACName: 2-[(2-amino-4-methylpentanoyl)amino]-3-methylbutanoic acid. Canonical SMILES: CC(C)CC(C(=O)NC(C(C)C)C(=O)O)N. Density: 1.066g/cm³. Product ID: ACM35436830. Alfa Chemistry ISO 9001:2015 Certified. | |
| Hepcidin-25 (human) | Hepcidin-25 (hepatic bactericidal protein), also known as LEAP-1 (liver-expressed antimicrobial peptide), is found independently in human blood ultrafiltration and urine. It is mainly expressed in liver and belongs to a new family of small vertebrate antimicrobial peptides that contain 8 cysteine residues and has obvious antibacterial and antifungal activities. Hepcidin is the main human iron regulatory hormone, which can bind to iron exporter ferroportin and induce its internalization and degradation, thus blocking iron efflux from cells. Uses: Anti-infective agents. Synonyms: LEAP-1 (human); H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22); L-alpha-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->13),(11->19),(14->22)-tetrakis(disulfide); Hepcidin Hepc25 (human); Hepcidin-25. Grades: ≥95% by HPLC. CAS No. 1356390-47-0. Molecular formula: C113H170N34O31S9. Mole weight: 2789.35. | |
| Hydroflumethiazide | Hydroflumethiazide is an anti-hypertensive and a diuretic drug. It is a sodium-chloride symporter inhibitor under the development of Shire and was approved by FDA in 1959. Uses: Anti-hypertensive and a diuretic drug. Synonyms: 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; Bristab; Bristurin; Dihydroflumethiazide; Diucardin; Elodrine; Finuret; Flutizide; Glomerulin; Hidroalogen; Leodrine; Saluron; Vergonil. Grades: 97%. CAS No. 135-09-1. Molecular formula: C8H8F3N3O4S2. Mole weight: 331.29. | |
| Iron(III) oxide | Iron(III) oxide. Synonyms: Ferric hydroxide oxide. CAS No. 20344-49-4. Product ID: CDC10-0159. Molecular formula: FeO2H. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Iron(III) oxide; CDC10-0159; 20344-49-4; FeO2H; Ferric hydroxide oxide; 243-746-4; MFCD00064782; 20344-49-4. Grade: catalyst grade. Color: Red-brown. EC Number: 243-746-4. Physical State: Powder. Quality Level: 100. Melting Point: 135°C. Density: 3.4-3.9 g/cm3. | |
| Lefamulin acetate | Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-3781 acetate. CAS No. 1350636-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16908A. | |
| Leniolisib | Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor. Leniolisib has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173. CAS No. 1354690-24-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17635. | |
| Leniolisib | Leniolisib is a PI3K (phosphatidylinositol 3-kinase) inhibitor. No detailed information has been published yet. Synonyms: (S)-1-(3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one;UNII-L22772Z9CP. Grades: 98%. CAS No. 1354690-24-6. Molecular formula: C21H25F3N6O2. Mole weight: 450.46. | |
| Leniolisib phosphate | Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. Leniolisib phosphate has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173 phosphate. CAS No. 1354691-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17635A. | |
| Leu-Val-OH | Leu-Val-OH. Group: Biochemicals. Grades: Reagent Grade. CAS No. 13588-95-9. Pack Sizes: 1g, 2.5g. US Biological Life Sciences. | Worldwide |
| Leu-Val-OH | Synonyms: L-Leucyl-L-valine; Leu Val OH. Grades: ≥ 99% (HPLC). CAS No. 13588-95-9. Molecular formula: C11H22N2O3. Mole weight: 230.31. | |
| Lexanopadol | Lexanopadol is a potent Opioid mu receptor agonist originated by Grunenthal. Lexanopadol is suited for the management of moderate to severe chronic pain, including neuropathic pain. No recent reports of development were identified for phase-I development in Pain in Germany. Uses: Pain. Synonyms: GRT6006; GRT 6006; GRT-6006; GRT-13106G; GRT 13106G; GRT13106G; Lexanopadol; (1r,4r)-6'-fluoro-N-methyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine;trans-6'-Fluoro-N-methyl-4-phenyl-4',9'-dihydro-3'H-spiro(cyclohexane-1,1'-pyrano(3,4-b)indol)-4-amine;GRT6006. Grades: 98%. CAS No. 1357348-09-4. Molecular formula: C23H25FN2O. Mole weight: 364.46. | |
| LL-37 (scrambled) | LL-37 (scrambled) is the control peptide for LL-37. Synonyms: Cationic Antimicrobial Protein 18 (134-170) (Scrambled) (human); H-Gly-Leu-Lys-Leu-Arg-Phe-Glu-Phe-Ser-Lys-Ile-Lys-Gly-Glu-Phe-Leu-Lys-Thr-Pro-Glu-Val-Arg-Phe-Arg-Asp-Ile-Lys-Leu-Lys-Asp-Asn-Arg-Ile-Ser-Val-Gln-Arg-OH; hCAP-18 (134-170); glycyl-L-leucyl-L-lysyl-L-leucyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-phenylalanyl-L-seryl-L-lysyl-L-isoleucyl-L-lysyl-glycyl-L-alpha-glutamyl-L-phenylalanyl-L-leucyl-L-lysyl-L-threonyl-L-prolyl-L-alpha-glutamyl-L-valyl-L-arginyl-L-phenylalanyl-L-arginyl-L-alpha-aspartyl-L-isoleucyl-L-lysyl-L-leucyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-arginyl-L-isoleucyl-L-seryl-L-valyl-L-glutaminyl-L-arginine. Grades: ≥95%. CAS No. 1354065-56-7. Molecular formula: C205H340N60O53. Mole weight: 4493.33. | |
| Maxadilan | Maxadilan, a potent vasodilator isolated from the salivary glands of the sand fly Lutzomyia longipalpis, specifically and effectively activates the mammalian PAC1 receptor, one of the three receptors of PACAP. Synonyms: H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Leu-Gln-Thr-Ser-Val-Gln-Thr-Thr-Ala-Thr-Phe-Thr-Ser-Met-Asp-Thr-Ser-Gln-Leu-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys51); Maxadilan (Lutzomyialongipalpis); L-cysteinyl-L-alpha-aspartyl-L-alanyl-L-threonyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-alanyl-L-isoleucyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-glutaminyl-L-lysyl-L-glutaminyl-L-alanyl-L-histidyl-L-histidyl-L-seryl-L-asparagyl-L-valyl-L-leucyl-L-glutaminyl-L-threonyl-L-seryl-L-valyl-L-glutaminyl-L-threonyl-L-threonyl-L-alanyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-methionyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-glutaminyl-L-leucyl-L-prolyl-glycyl-L-asparagyl-L-seryl-L-valyl-L-phenylalanyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-methionyl-L-lysyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-alaninamide (1->5),(14->51)-bis(disulfide). Grades: 95%. CAS No. 135374-80-0. Molecular formula: C291H466N86O94S6. Mole weight: 6865.82. | |
| MDL 29913 | MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS. Synonyms: MDL 29913; MDL29913; MDL-29913; 1,4,7,10,13,16-Hexaazacyclooctadecane, Cyclic Peptide Deriv.; N-(2-Amino-4-methylpentyl)?-N-methyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-phenylalanylglycine (5?1)?-Lactam. Grades: >97%. CAS No. 135721-56-1. Molecular formula: C40H56N8O6. Mole weight: 744.92. | |
| Methyclothiazide | Methyclothiazide is an orally active antihypertensive agent and a diuretic agent. Methyclothiazide leads to a reduction of the vascular response to the action of endogenous vasoconstricting stimuli, such as Norepinephrine (HY-13715). Methyclothiazide is against voltage-dependent Ca-channel ( VDCC ) activity in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 135-07-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0562. | |
| Mitoxantrone dihydrochloride | Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity [1] [2] [3] [4]. Mitoxantrone dihydrochloride also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502A. | |
| MK 287 | MK-287 is platelet activating factor (PAF) inhibitor originated by Merck & Co. It can potently inhibit [3H]C18-PAF binding to human platelet, PMN (polymorphonuclear leukocyte) and lung membranes. The inhibitory effects are competitive and stereospecific. Clinical trials for asthma was discontinued. Uses: Asthma. Synonyms: MK-287; MK 287; MK287; L-680573; L 680573; L680573;2-((3-methoxy-2-propoxy-5-((2S,5S)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran-2-yl)phenyl)sulfonyl)ethan-1-ol. Grades: 98%. CAS No. 135947-75-0. Molecular formula: C25H34O9S. Mole weight: 510.60. | |
| ONO-4059 | ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one; ONO-4059; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. Grades: 98%. CAS No. 1351636-18-4. Molecular formula: C25H22N6O3. Mole weight: 454.48. | |
| Orismilast | Orismilast (LEO-32731) is an orally active and selective PDE4 inhibitor used for the research of inflammatory diseases. Orismilast demonstrates potent inhibition of PDE4B and PDE4D subtype splice variants [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LEO-32731. CAS No. 1353546-86-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117960. | |
| Osavampator | Osavampator (TAK-653) is a AMPA receptor positive allosteric modulator. Osavampator selectively binds to AMPA-R in a glutamate-dependent manner and induces Ca 2+ influx in hGluA1i CHO cells (EC 50 = 3.3 μM). Osavampator improves learning and memory in many models. Osavampator is can be used for the research of depressive disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-653; NBI-1065845. CAS No. 1358751-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115864. | |
| Palladium | Palladium on carbon, often referred to as Pd/C, is a form of palladium used as a catalyst. The metal is supported on activated carbon in order to maximize its surface area and activity. Uses: Among the platinum group metals, palladium is the least noble metal, exhibiting greater reactivity than other metals of the group. the metal forms mostly bivalent compounds, although a small number of tetravalent and a fewer trivalent compounds are known. palladium exhibits a strong tendency to form complexes, most of which are four-coordinated square planar complexes of the metal in +2 oxidation. Additional or Alternative Names: ESCAT 1391;ESCAT 1371;ESCAT 1351;Paladium;PALLIDIUM. Appearance: Powder. CAS No. 7440-5-3. Molecular formula: Pd. Mole weight: 106.42. IUPACName: palladium. Canonical SMILES: [Pd]. Density: 1.025 g/mL at 25ºC. ECNumber: 231-115-6. Product ID: ACM7440053. Alfa Chemistry ISO 9001:2015 Certified. | |
| PGLa-H | PGLa-H is an antimicrobial peptide found in Xenopus laevis (African clawed frog), and has antibacterial activity. Synonyms: Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu. Grades: ≥97%. CAS No. 1350308-37-0. Molecular formula: C50H95N13O11. Mole weight: 1054.37. | |
| Piroctone olamine | Piroctone olamine. Synonyms: Piroctone Olamine. CAS No. 68890-66-4. Product ID: CDC10-0348. Molecular formula: C16H30N2O3. Category: Cosmetic Preservatives. Product Keywords: Cosmetic Ingredients; Cosmetic Preservatives; Piroctone olamine; CDC10-0348; 68890-66-4; C16H30N2O3; Piroctone Olamine; 272-574-2; MFCD01690792; 68890-66-4. Purity: ≥99.0% (HPLC). Color: White to off-white. EC Number: 272-574-2. Physical State: neat. Solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly). Quality Level: 100. Storage: Inert atmosphere,2-8°C. Application: Refer to the product's Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Boiling Point: 344.1ºC at 760 mmHg. Melting Point: 130 - 135ºC. Product Description: Piroctone olamine is a pyridone derivative, which is known to have bactericidal effects on gram-positive and gram-negative bacteria and fungicidal effects and hence is a component of many cosmetic products such as anti-dandruff shampoo. | |
| Poly(2-vinylpyridine) | Vinylpyridines, stabilized is a colorless to light yellow liquid that consists of a mixture of isomers. Insoluble in water and less dense than water. Floats on water. Contact irritates skin, eyes, and mucous membranes. Toxic by ingestion.;Liquid;COLOURLESS LIQUID WITH PUNGENT ODOUR. Group: Reference-calibration standards. Alternative Names: RALU(R)PLATE LEV 170; POLY(2-VINYLPYRIDINE) CROSS-LINKED; POLY(2-VINYLPYRIDINE), LINEAR; POLY(2-VINYLPYRIDINE); POLY(2-VINYLPYRIDINE) 115000; POLY(2-VINYLPYRIDINE) 12000; POLY(2-VINYLPYRIDINE) 135000; POLY(2-VINYLPYRIDINE) 21000. CAS No. 25014-15-7. Product ID: 2-ethenylpyridine. Molecular formula: 105.14g/mol. Mole weight: C7H7N;H2C=CHC5H4N;C7H7N. C=CC1=CC=CC=N1. InChI=1S / C7H7N / c1-2-7-5-3-4-6-8-7 / h2-6H, 1H2. KGIGUEBEKRSTEW-UHFFFAOYSA-N. | |
| protein geranylgeranyltransferase type I | This enzyme, along with protein farnesyltransferase (EC 2.5.1.58) and protein geranylgeranyltransferase type II (EC 2.5.1.60), constitutes the protein prenyltransferase family of enzymes. Catalyses the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. These protein acceptors have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine; serine, methionine, alanine or glutamine makes the protein a substrate for EC 2.5.1.58. The enzymes are relaxed in specificity for A1, but cannot act if A2 is aromatic. Known targets of this enzyme include most γ-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families. A zinc metalloenzyme. The Zn2+ is required for peptide, but not for isoprenoid, substrate binding. Group: Enzymes. Synonyms: GGTase-I; GGTaseI. Enzyme Commission Number: EC 2.5.1.59. CAS No. 135371-29-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2796; protein geranylgeranyltransferase type I; EC 2.5.1.59; 135371-29-8; GGTase-I; GGTaseI. Cat No: EXWM-2796. |  |
| Rifamycin S | Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA ). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 13553-79-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-125365. | |
| (Ser(PO3H2)516)-Artemis (511-523) | Artemis, a phosphorylated protein, plays a role in V(D)J recombination, non-homologous end-joining of double-strand breaks, and regulation of G2/M cell cycle checkpoints induced by DNA damage. Synonyms: H-Thr-Val-Ala-Gly-Gly-Ser(PO3H2)-Gln-Ser-Pro-Lys-Leu-Phe-Ser-OH; L-Serine, L-threonyl-L-valyl-L-alanylglycylglycyl-O-phosphono-L-seryl-L-glutaminyl-L-seryl-L-prolyl-L-lysyl-L-leucyl-L-phenylalanyl-. Grades: ≥95%. CAS No. 2243207-01-2. Molecular formula: C56H92N15O22P. Mole weight: 1358.41. | |
| SKLB-1028 | SKLB1028 is a novel Bcr-abl tyrosine kinase inhibitor, Epidermal growth factor inhibitor and Fms-like tyrosine kinase 3 inhibitor originated by CSPC Ouyi Pharmaceutical. Phase-I clinical trials in Acute myeloid leukaemia (Monotherapy, Second-line therapy or greater) in China is on-going. Uses: Acute myeloid leukaemia. Synonyms: SKLB-1028; SKLB 1028; SKLB1028; 9-isopropyl-N2-(4-(4-methylpiperazin-1-yl)phenyl)-N8-(pyridin-3-yl)-9H-purine-2,8-diamine. Grades: 98%. CAS No. 1350544-93-2. Molecular formula: C24H29N9. Mole weight: 443.56. | |
| (S)-Verapamil hydrochloride | (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(-)-Verapamil hydrochloride. CAS No. 36622-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135336A. | |
| T-3364366 | T-3364366 is a reversible and slow-binding Delta-5 desaturase (D5D) inhibitor. Ki is less than 2.7 nM and a dissociation half-life is more than 2.0 h. D5D is an attractive drug target for inflammatory-related. Uses: Inflammatory-related. Synonyms: T-3364366, T 3364366, T3364366; N-(2-((4-oxo-3-(4-(2,2,2-trifluoroethoxy)phenyl)-3,4-dihydrothieno[3,4-d]pyrimidin-2-yl)thio)ethyl)acetamide. Grades: 98%. CAS No. 1356354-09-0. Molecular formula: C18H16F3N3O3S2. Mole weight: 443.46. | |
| Vasculotide | Vasculotide, an angiopoietin-1 mimetic, is a Tie-2 activator and induces Tie-2 phosphorylation. Vasculotide has anti-inflammatiory effect and anti-permeability. Vasculotide ameliorates endotoxin-induced endothelial barrier dysfunction. Vasculotide promotes angiogenesis in a mouse model of diabetic ulcer. Vasculotide protects mice from vascular leakage and reduces mortality in murine abdominal sepsis. Vasculotide decreases microvascular leakage and improves microcirculatory perfusion in a rat model of hemorrhagic shock [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1359657-45-6. Pack Sizes: 1 mg. Product ID: HY-P10580. | |
| VPC-70063 | VPC-70063 is a Myc-Max inhibitor. VPC-70067 is a close analog of the previously identified Myc inhibitor 10058-F4. VPC-70063, of a chemically different scaffold, was the best performer in a panel of in vitro assays, and the forerunner for future hit-to-lead optimization efforts. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VPC-70063; VPC 70063; VPC70063. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 13571-44-3. Molecular formula: C16H12F6N2S. Mole weight: 378.34. Purity: >98%. IUPACName: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)thiourea. Canonical SMILES: S=C(NCC1=CC=CC=C1)NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2. Product ID: ACM13571443. Alfa Chemistry ISO 9001:2015 Certified. | |
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