Leukocyte Suppliers USA
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Product | Description | |
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Leukocyte Proteinase-3(169-177) Quick inquiry Where to buy Suppliers range | Leukocyte Proteinase-3 (Wegener's autoantigen). Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-549. | |
Genomic DNA, Human Adult Normal, Peripheral Blood Leukocyte, Single Donor, BioGenomics Quick inquiry Where to buy Suppliers range | DNA is isolated by proprietary modified guanidine thiocyanate techniques. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Tissue, Genomic DNA Plate, Human Adult Normal, Peripheral Blood Leukocyte, BioGenomics Quick inquiry Where to buy Suppliers range | Genomic DNAs are extracted from tissues from as many as 96 individual donors. The genomic DNAs are extracted and purified using proprietary techniques that yield high molecular weight material, as verified by agarose gel electrophoresis. 96 Well Genomic DNA Plates can be used as Reference Standard materials for gene expression research. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 96Tests. US Biological Life Sciences. | Worldwide |
Tissue, Membrane Protein, Human Adult Normal, Peripheral blood leukocyte HisTek Quick inquiry Where to buy Suppliers range | Tissue Protein Lysate produced under consistent processing conditions to ensure intact structure and original nature. Total protein is prepared from whole-tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Tissue, Total Protein, Human Adult Normal, Peripheral blood leukocyte HisTek Quick inquiry Where to buy Suppliers range | Tissue Protein Lysate produced under consistent processing conditions to ensure intact structure and original nature. Total protein is prepared from whole-tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Tissue, Total RNA, Human Adult Normal, Peripheral blood leukocyte, BioGenomics Quick inquiry Where to buy Suppliers range | Total RNAs are available from almost 200 different human adult and fetal normal tissues, human diseased and tumor tissues, as well as mouse, rat, and monkey tissues. Total RNAs are provided ready-to-use for Northern blotting, cDNA synthesis, RNA protection, and RNA differential display. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester Quick inquiry Where to buy Suppliers range | 1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester is a useful synthetic intermediate. It can be used to prepare Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3. Group: Biochemicals. Grades: Highly Purified. CAS No. 7459-46-3. Pack Sizes: 5g, 10g. Molecular Formula: C11H18O6. US Biological Life Sciences. | Worldwide |
12(S)-HpETE Quick inquiry Where to buy Suppliers range | 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grades: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5. | |
12(S)-HPETE Quick inquiry Where to buy Suppliers range | 12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO. Group: Biochemicals. Grades: Highly Purified. CAS No. 71774-10-2. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. | Worldwide |
17(R)-Resolvin D1 Quick inquiry Where to buy Suppliers range | 17(R)-Resolvin D1 is an exhibitor of a dose-dependent reduction in leukocyte infiltration. Group: Biochemicals. Grades: Highly Purified. CAS No. 528583-91-7. Pack Sizes: 10ug, 25ug. Molecular Formula: C22H32O5, Molecular Weight: 376.49. US Biological Life Sciences. | Worldwide |
2,6-DICHLORO-9-METHYLPURINE Quick inquiry Where to buy Suppliers range | 2,6-DICHLORO-9-METHYLPURINE acts as a reagent in the synthesis of highly selective inhibitors of PI3K-δ used in the treatment of inflammatory diseases such as leukocyte related illnesses. Group: Biochemicals. Grades: Highly Purified. CAS No. 2382-10-7. Pack Sizes: 500mg, 1g. Molecular Formula: C6H4Cl2N4, Molecular Weight: 203.03. US Biological Life Sciences. | Worldwide |
2'-Deoxy-N-ethylguanosine Quick inquiry Where to buy Suppliers range | 2'-Deoxy-N-ethylguanosine is an acetaldehyde derived DNA adduct formed in healthy individuals' leukocyte DNA after alcohol consumption. Synonyms: N2-Ethyl-2'-deoxyguanosine; Guanosine, 2'-deoxy-N-ethyl-. Grades: 96%. CAS No. 101803-03-6. Molecular formula: C12H17N5O4. Mole weight: 295.29. | |
2'-Deoxy-N-ethylguanosine-d5 Quick inquiry Where to buy Suppliers range | Isotope labelled analog of 2'-Deoxy-N-ethylguanosine, an acetaldehyde derived DNA adduct formed in healthy individuals' leukocyte DNA after alcohol consumption. Synonyms: N2-Ethyl-2'-deoxyguanosine-d5. Molecular formula: C12H12D5N5O4. Mole weight: 300.33. | |
2-Hydroxy-4-methylpyridine-d3 Quick inquiry Where to buy Suppliers range | 2-Hydroxy-4-methylpyridine-d3 is the isotope labelled analog of 2-Hydroxy-4-methylpyridine (H949890); an intermediate used to prepare oxobenzopyrancarboxyl ate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino) (pyridinyloxy) pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185316-03-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H4D3NO, Molecular Weight: 112.14. US Biological Life Sciences. | Worldwide |
2-Hydroxy-4-methylpyridine-d6 Quick inquiry Where to buy Suppliers range | 2-Hydroxy-4-methylpyridine-d6 is the isotope labelled analog of 2-Hydroxy-4-methylpyridine (H949890); an intermediate used to prepare oxobenzopyrancarboxyl ate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino) (pyridinyloxy) pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 916979-13-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6HD6NO, Molecular Weight: 115.16. US Biological Life Sciences. | Worldwide |
2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride double salt Quick inquiry Where to buy Suppliers range | 2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride double salt (CAS# 67801-08-5) is used in preparation of aryl amino acid and peptide esters as enzyme substrates for leukocyte detection. Synonyms: 2-Methoxy-4-(morpholin-4-yl)benzenediazonium tetrachlorozincate (2:1). Grades: 95 %. CAS No. 67801-08-5. Molecular formula: C22H28Cl4N6O4Zn. Mole weight: 647.7. | |
(2R,4S)-4-Amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | (2R,4S)-4-Amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic Acid Ethyl Ester is derived from 4- (Trifluoromethyl) aniline (T791050), which is a 4-substituted aniline derivative, exert special hematotoxicity on the red blood cells and induce leukocytosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 261947-64-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H19F3N2O2, Molecular Weight: 316.32. US Biological Life Sciences. | Worldwide |
2-Tetradecylhexadecanoic Acid Quick inquiry Where to buy Suppliers range | 2-Tetradecylhexadecanoic acid is used as a reagent to synthesize E-selectin blockers. E-Selectin is an intracellular adhesion molecule that recruits leukocytes (T-helper-1 cells) into inflamed tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 66880-77-1. Pack Sizes: 1g, 10g. Molecular Formula: C30H60O2. US Biological Life Sciences. | Worldwide |
2-Tetradecylhexadecanoic Acid Ethyl-d5 Ester Quick inquiry Where to buy Suppliers range | 2-Tetradecylhexadecanoic Acid Ethyl-d5 Ester is labelled 2-Tetradecylhexadecanoic Acid Ethyl Ester (T292215), the ethyl ester of 2-Tetradecylhexadecanoic acid (T292210) which is used as a reagent to synthesize E-selectin blockers. E-Selectin is an intracellular adhesion molecule that recruits leukocytes (T-helper-1 cells) into inflamed tissues. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C32H59D5O2, Molecular Weight: 485.88. US Biological Life Sciences. | Worldwide |
2-Tetradecylhexadecanoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | 2-Tetradecylhexadecanoic Acid Ethyl Ester is the ethyl ester of 2-Tetradecylhexadecanoic acid (T292210) which is used as a reagent to synthesize E-selectin blockers. E-Selectin is an intracellular adhesion molecule that recruits leukocytes (T-helper-1 cells) into inflamed tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 86302-97-8. Pack Sizes: 500mg, 5g. Molecular Formula: C32H64O2, Molecular Weight: 480.85. US Biological Life Sciences. | Worldwide |
2-Tetradecylhexadecanoic Acid Methyl-d3 Ester Quick inquiry Where to buy Suppliers range | 2-Tetradecylhexadecanoic Acid Methyl-d3 Ester is labelled 2-Tetradecylhexadecanoic Acid Methyl Ester (T292225), the methyl ester of 2-Tetradecylhexadecanoic acid (T292210) which is used as a reagent to synthesize E-selectin blockers. E-Selectin is an intracellular adhesion molecule that recruits leukocytes (T-helper-1 cells) into inflamed tissues. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C31H59D3O2, Molecular Weight: 469.84. US Biological Life Sciences. | Worldwide |
2-Tetradecylhexadecanoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 2-Tetradecylhexadecanoic Acid Methyl Ester is the methyl ester of 2-Tetradecylhexadecanoic acid (T292210) which is used as a reagent to synthesize E-selectin blockers. E-Selectin is an intracellular adhesion molecule that recruits leukocytes (T-helper-1 cells) into inflamed tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 180476-34-0. Pack Sizes: 500mg, 5g. Molecular Formula: C31H62O2, Molecular Weight: 466.82. US Biological Life Sciences. | Worldwide |
2- (Trifluoromethyl) aniline-d2 Quick inquiry Where to buy Suppliers range | o-Aminobenzotrifluoride-d2 is a 4-substituted aniline derivative that exerts special hematotoxicity on red blood cells and induce leukocytosis. o-Aminobenzotrifluoride-d2 is a thiohydrazides used as an antibacterial remedy for Chlamydial infection treatment at chronic stages of infections. Group: Biochemicals. Alternative Names: 2- (Trifluoromethyl) aniline-d2; 2- (Trifluoromethyl) benzenamine-d2; 2-Amino-α, α, α-trifluorotoluene-d2; 2-Aminobenzotrifluoride-d2; 2-Trifluoro methyl phenylamine-d2; NSC 10336-d2; o- (Trifluoromethyl) aniline-d2; o- (Trifluoromethyl) phenylamine-d2. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
3-Deazaadenosine (4-Amino-1-(ß-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine) Quick inquiry Where to buy Suppliers range | Possesses antiviral activity. It is an inhibitor of leukocyte adhesion to TNF-treated endothelial cells. Group: Biochemicals. Alternative Names: 4-Amino-1-(ß-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
3-Deazaadenosine hydrochloride Quick inquiry Where to buy Suppliers range | It is an S-adenosine homocysteine hydrolase inhibitor. It has anti-inflammatory effects, inhibiting leukocyte adhesion and chemotaxis, lymphocyt-mediated cytolysis, phagocytosis, degranulation and NF-κB signal transduction. Synonyms: 3-Deaza-Adenosine hydrochloride; 3-Deaza-rA Hcl; 1-(β-D-Ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine hydrochloride (1:1); 1H-Imidazo[4,5-c]pyridin-4-amine, 1-β-D-ribofuranosyl-, hydrochloride (1:1). Grades: ≥97% by HPLC. CAS No. 86583-19-9. Molecular formula: C11H15ClN4O4. Mole weight: 302.71. | |
3-Hydroxy-5-phenylpyrrole (HOPPy) Quick inquiry Where to buy Suppliers range | Used for detecting the presence of hydrolytic analytes, such as leukocytes, esterase, and protease. The detection of leukocytes is especially important in medical diagnostics. Group: Biochemicals. Alternative Names: HOPPy. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
3-Sialyl Lewis X- biotin Quick inquiry Where to buy Suppliers range | 3-Sialyl Lewis X-biotin is a compound used for the detection and study of cell adhesion molecules involved in inflammation, cancer metastasis is and leukocyte recruitment. It is an effective tool for labeling and visualizing selectin ligands. This compound is widely employed in research related to drugs targeting selectin-mediated cell adhesion and therapies for diseases like cancer and inflammation. Molecular formula: C56H95N7O26S. Mole weight: 1314.45. | |
3'-Sialyl Lewis X-sp-biotin Quick inquiry Where to buy Suppliers range | 3'-Sialyl Lewis X is a carbohydrate antigen mainly found on tumor cells as well as on leukocytes that play important roles in the immune response. 3'-Sialyl Lewis X-sp-biotin is a biotin-conjugated small molecule that specifically recognizes and binds to 3'-Sialyl Lewis X, making it a valuable tool in diagnostics and biomedical research related to cancer and inflammation. Grades: 95%. Molecular formula: C50H84N6O26S. Mole weight: 1217.29. | |
4- (Trifluoromethyl) aniline Quick inquiry Where to buy Suppliers range | 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis. Group: Biochemicals. Alternative Names: 4- (Trifluoromethyl) benzenamine. Grades: Highly Purified. CAS No. 455-14-1. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
4-(Trifluoromethyl)aniline Quick inquiry Where to buy Suppliers range | 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis. Synonyms: 4-(trifluoromethyl)aniline. Grades: 98 %. CAS No. 455-14-1. Molecular formula: C7H6F3N. Mole weight: 161.12. | |
Ac2-12 Quick inquiry Where to buy Suppliers range | Ac2-12 is an annexin/lipocortin 1-mimetic peptide that inhibits leukocyte extravasation. It promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo. It reduces neutrophil adhesion and emigration. It has an anti-inflammatory effect. Synonyms: LPC1; ANX1; ANXA-1. CAS No. 256447-08-2. Molecular formula: C63H94N14O17S. Mole weight: 1351.58. | |
Ac2-26 Quick inquiry Where to buy Suppliers range | Ac2-26 is an annexin/lipocortin 1-mimetic peptide that inhibits leukocyte extravasation. It promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic injury in mice in vivo. It reduces neutrophil adhesion and emigration. It has an anti-inflammatory effect. Synonyms: Annexin-1 (2-26) (human); Ac2-26; Lipocortin-1 (2-26); Calpactin II (1-25) (dephosphorylated) (human); Annexin A1 (1-25) (dephosphorylated) (human); Annexin A1 (1-25) (dephosphorylated) (human); Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH. Grades: >98%. CAS No. 151988-33-9. Molecular formula: C141H210N32O44S. Mole weight: 3089.43. | |
Ac2-26 TFA Quick inquiry Where to buy Suppliers range | Ac2-26 TFA is an annexin/lipocortin 1-mimetic peptide that inhibits leukocyte extravasation. It promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic injury in mice in vivo. It reduces neutrophil adhesion and emigration. It has anti-inflammatory effect. Synonyms: Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys.TFA; Annexin A1 (1-25) (dephosphorylated) (human).TFA; L-Lysine, N-acetyl-L-alanyl-L-methionyl-L-valyl-L-seryl-L-α-glutamyl-L-phenylalanyl-L-leucyl-L-lysyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-, trifluoroacetic acid. Grades: ≥95%. Molecular formula: C143H211F3N32O46S. Mole weight: 3203.45. | |
Ac9-25 Quick inquiry Where to buy Suppliers range | Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Synonyms: L-Lysine, N2-acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-; N2-Acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-L-lysine; Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH. Grades: ≥95%. CAS No. 284040-76-2. Molecular formula: C99H143N23O33. Mole weight: 2183.35. | |
Ac9-25 acetate Quick inquiry Where to buy Suppliers range | Ac9-25 acetate is an N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Synonyms: L-Lysine, N2-acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-, acetate; N2-Acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-L-lysine acetate; Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH acetate. Grades: ≥95%. Molecular formula: C101H147N23O35. Mole weight: 2243.38. | |
Acremonol Quick inquiry Where to buy Suppliers range | Acremonol has anti-gram-positive bacteria and fungus activity, 4μg/mL or more can reduce oxidative rupture of dog polymorphonuclear leukocytes (PMNL). Molecular formula: C14H18O6. Mole weight: 282.29. | |
Annexin A1 (1-25) (dephosphorylated) (human) Quick inquiry Where to buy Suppliers range | Ac2-26 is Annexin A1 (AnxA1) N-terminal-derived peptide, and acts as inhibitor of leukocyte extravasation. It can reduce neutrophil adhesion and emigration, promote detachment of neutrophils from activated mesenteric endothelium and accelerate epithelial wound repair after induced colonic injury in mice in vivo. It shows anti-inflammatory effect. Uses: API. CAS No. 151988-33-9. Product ID: 10-101-239. | |
apigenin-7-O-glucronide Quick inquiry Where to buy Suppliers range | Apigenin-7-glucuronide inhibited the major pathways of arachidonate metabolism in leukocytes. Synonyms: 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranosiduronic acid. Grades: >98%. CAS No. 29741-09-1. Molecular formula: C21H18O11. Mole weight: 446.4. | |
Arg-Gly-Asp-Ser Quick inquiry Where to buy Suppliers range | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
Arg-Gly-Asp-Ser acetate Quick inquiry Where to buy Suppliers range | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Molecular formula: C17H31N7O10. Mole weight: 493.47. | |
Auranofin Quick inquiry Where to buy Suppliers range | Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Synonyms: SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2, 3, 4, 6-tetraacetato] (triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [ (Tetra-O-acetyl-β -D-glucopyranosyl)thio] (triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D. Grades: ≥98%. CAS No. 34031-32-8. Molecular formula: C20H34AuO9PS. Mole weight: 678.49. | |
BayCysLT2 Quick inquiry Where to buy Suppliers range | BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. Synonyms: CAY10633; 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid. Grades: ≥95%. CAS No. 712313-33-2. Molecular formula: C34H39NO8. Mole weight: 589.7. | |
BMS 470539 dihydrochloride Quick inquiry Where to buy Suppliers range | BMS 470539 dihydrochloride is a potent and selective melanocortin MC1 receptor agonist (IC50 = 120 nM) with anti-inflammatory activity. It also inhibits leukocyte trafficking. Synonyms: BMS 470539 dihydrochloride; BMS470539 dihydrochloride; BMS-470539 dihydrochloride; 1-[1-(3-Methyl-L-histidyl-O-methyl-D-tyrosyl)-4-phenyl-4-piperidinyl]-1-butanone dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C32H41N5O4.2HCl. Mole weight: 632.62. | |
BMS 688521 Quick inquiry Where to buy Suppliers range | BMS 688521 is a small molecule antagonist of leukocyte function associated antigen-1 (LFA-1). It has provided proof-of-concept for LFA-1 as an immunological target. BMS 688521 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 2.5 and 78 nM in HUVEC adhesion and mouse specific adhesion assays respectively), which inhibits eosinophil accumulation in the lungs in a mouse allergic eosinophilic lung inflammation model. Synonyms: 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid; BMS-688521; BMS688521; SCHEMBL5392413. Grades: ≥98%. CAS No. 893397-44-9. Molecular formula: C26H19Cl2N5O4. Mole weight: 536.37. | |
BW-B 70C Quick inquiry Where to buy Suppliers range | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
BX471 (N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea, ZK-811752) Quick inquiry Where to buy Suppliers range | An orally active, selective antagonist for chemokine receptor 1 (CCR-1) (Ki = 1-5nM). Has been used in studies related to intracellular calcium mobilization and migration of leukocytes mediated through CCR-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 217645-70-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Cathepsin G Inhibitor I Quick inquiry Where to buy Suppliers range | Cathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G with IC50 of 53 nM. It weakly inhibits chymotrypsin and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase. Synonyms: Cathepsin G Inhibitor I; 429676-93-7; Cathepsin G Inhibitor; CHEMBL164694; [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid; SCHEMBL1613660; DTXSID80431393; BDBM50139754; HY-103351; CS-0027703; A918760; (2-{3-[(1-Benzoyl-piperidin-4-yl)-methyl-carbamoyl]-naphthalen-2-yl}-1-naphthalen-1-yl-2-oxo-ethyl)-phosphonic acid; [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2 oxoethyl]phosphonic acid. Grades: ≥95%. CAS No. 429676-93-7. Molecular formula: C36H33N2O6P. Mole weight: 620.6. | |
CAY10583 Quick inquiry Where to buy Suppliers range | Leukotriene B4 (LTB4) is a leukotriene involved in inflammation. It is produced from leukocytes in response to inflammatory mediators and is able to induce the adhesion and activation of leukocytes on the endothelium, allowing them to bind to and cross it into the tissue. CAY10583 is a selective and synthetic LTB4 agonist with EC50 of 20 nM. Synonyms: CAY 10583; CAY-10583. Grades: ≥98%. CAS No. 862891-27-8. Molecular formula: C25H25NO3. Mole weight: 387.5. | |
CAY10606 Quick inquiry Where to buy Suppliers range | Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme that in humans is encoded by the ALOX5 gene. 5-LO initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 is a potent, reversible inhibitor of 5-LO, both in cell-free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-LO is activated with the calcium ionophore A23187 with IC50 of 1.6 μM. Synonyms: CAY 10606; CAY-10606. Grades: ≥98%. CAS No. 1159576-98-3. Molecular formula: C22H18ClNO3. Mole weight: 379.8. | |
CAY10649 Quick inquiry Where to buy Suppliers range | Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme that in humans is encoded by the ALOX5 gene. 5-LO initiates the synthesis of (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with IC50 of 0.28 μM. Synonyms: CAY 10649; CAY-10649. Grades: ≥98%. CAS No. 1272519-89-7. Molecular formula: C17H12ClNO2S. Mole weight: 329.8. | |
Chymostatin Quick inquiry Where to buy Suppliers range | Chymostatin is a bioactive peptide that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase, but it cannot block the activity of cathepsins, papain, and leukocyte elastase effectively. It doesn't have effect on trypsin, thrombin, plasmin, pepsin, and kallikrein. Uses: Serine proteinase inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu B=Val C=Ile]-phenylalaninal (Mixture). Grades: ≥95% (a mixture of A, B, C). CAS No. 9076-44-2. Molecular formula: CxHyN7O6. Mole weight: 607.7. | |
CJ-13610 Quick inquiry Where to buy Suppliers range | CJ-13610 is an inhibitor of 5-lipoxygenase (5-LO). It inhibits 5-LO product formation in human polymorphonuclear leukocytes (PMNLs) challenged with A23187 in vitro. It also inhibits 5-LO product formation induced by phosphorylation in PMNLs and HeLa cells. Synonyms: 4-[3-[4-(2-methylimidazol-1-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide; Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide. Grades: ≥98%. CAS No. 179420-17-8. Molecular formula: C22H23N3O2S. Mole weight: 393.5. | |
Defensin HNP-1 (human) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Defensin HNP-1 is a peptide secreted by polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It completely inhibits secretion of the exotoxin superantigen TSS toxin-1 (TSST-1) from S. aureus when used at a concentration of 50 ng/ml and inhibits anthrax lethal toxin. Synonyms: DEFA1 Protein; α-Defensin 1; Human Neutrophil Peptide 1; Neutrophil Defensin 1. Grades: ≥95%. Molecular formula: C150H222N44O38S6·xCF3COOH. Mole weight: 3442.04. | |
Defensin HNP-2 (human) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Defensin HNP-2 is a peptide with antimicrobial properties that is secreted by human polymorphonuclear leukocytes (PMNs). Defensin HNP-2 binds to recombinant HIV-1 envelope glycoprotein gp120 and human CD4. Synonyms: DEFA2 Protein; α-Defensin 2; Human Neutrophil Peptide 2; Neutrophil Defensin 2. Grades: ≥95%. Molecular formula: C147H217N43O37S6·xCF3COOH. Mole weight: 3370.96. | |
Defensin HNP-3 (human) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV). Synonyms: DEFA3 Protein; α-Defensin 3; Human Neutrophil Peptide 3; Neutrophil Defensin. Grades: ≥95%. Molecular formula: C151H222N44O40S6·xCF3COOH. Mole weight: 3486.05. | |
Deoxynivalenol Quick inquiry Where to buy Suppliers range | Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus. Group: Biochemicals. Alternative Names: (3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one; 4-Deoxynivalenol; 4-Desoxynivalenol; DON; Dehydronivalenol; NSC 269144; Vomitoxin. Grades: Highly Purified. CAS No. 51481-10-8. Pack Sizes: 2.5mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
Diflapolin Quick inquiry Where to buy Suppliers range | Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). It is selective for FLAP and sEH over other arachidonic acid metabolism enzymes. Diflapolin (1, 3, and 10 mg/kg) decreases inflammation in a mouse model of peritonitis induced by zymosan, reducing the production of LTB4 and LTC4 and inhibiting leukocyte recruitment. Grades: ≥98%. CAS No. 724453-98-9. Molecular formula: C22H17Cl2N3O2S. Mole weight: 458.36. | |
DMP 777 Quick inquiry Where to buy Suppliers range | DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. Synonyms: L-694458; L 694458; L694458; DMP-777; DMP777. Grades: >98%. CAS No. 157341-41-8. Molecular formula: C31H40N4O6. Mole weight: 564.67. | |
Elasnin Quick inquiry Where to buy Suppliers range | Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Synonyms: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,?5-Dibutyl-6-(1-butyl-2-oxoheptyl)?-4-hydroxy-2H-pyran-2-one. Grades: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57. | |
Elasnin (3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one) Quick inquiry Where to buy Suppliers range | Inhibitor of human leukocyte elastase (IC50=1.3ug/ml), different other elastases and chymotrypsin (IC50=82ug/ml). Group: Biochemicals. Grades: Highly Purified. CAS No. 68112-21-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Elastase Quick inquiry Where to buy Suppliers range | Elastase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;Elastase, pancreatic from porcine pancreas, 30 units/mg;Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free. CAS No. 39445-21-1. Pack Sizes: 1 g. Product ID: CDF4-0039. | |
Elastase Inhibitor V (2-(2-Bromophenyl)-5-chloro-3,1-benzoxazin-4-one) Quick inquiry Where to buy Suppliers range | A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 = 29.5nM), likely by covalently modifying active site serine. Shown to inhibit elastase secretion (IC50 = 80.8nM), but not O2 - generation, in fLMP-stimulated primary human neutrophil cultures. Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1mg/kg, i.v.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Elastatinal Quick inquiry Where to buy Suppliers range | Elastatinal is a potent and irreversible inhibitor of pancreatic elastase. It is a much stronger inhibitor of pancreatic elastase than the leukocyte-derived enzyme. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands. Synonyms: (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxyethyl]-L-glutamamide. Grades: ≥ 95 %. CAS No. 51798-45-9. Molecular formula: C21H36N8O7. Mole weight: 512.56. | |
eNAP-2 Quick inquiry Where to buy Suppliers range | ENAP-2 is a novel cysteine-rich bactericidal peptide from equine leukocytes. | |
Formyl-Met-Leu-Phe-OH - CAS 59880-97-6 Quick inquiry Where to buy Suppliers range | Chemotactic peptide for polymorphonuclear leukocytes. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 59880-97-6. Pack Sizes: 25MG. Mole weight: 437.55. Catalog: AP59880976. Assay: ≥99% (HPLC). | |
Gallinacin 2 Quick inquiry Where to buy Suppliers range | Gallinacin 2 is a cysteine-rich antimicrobial peptide of chicken leukocytes. Synonyms: Chp2 peptide; Thp2 peptide; gallinacin 2 protein, chicken. CAS No. 156409-45-9. Molecular formula: C205H322N60O48S6. Mole weight: 4587.50. | |
Go6983 Quick inquiry Where to buy Suppliers range | GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury. Synonyms: Go6983, Go-6983; Go 6983; GO6983. Grades: >98%. CAS No. 133053-19-7. Molecular formula: C26H26N4O3. Mole weight: 442.519. | |
GSK0660 Quick inquiry Where to buy Suppliers range | GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CCL17, and CXCL10, and it may block TNFα-induced retinal leukostasis. Synonyms: GSK0660; GSK-0660; GSK 0660. Grades: 96%. CAS No. 1014691-61-2. Molecular formula: C19H18N2O5S2. Mole weight: 418.48. | |
Hydroxyoctadecadienoic Acid 13(S) (HODE) Quick inquiry Where to buy Suppliers range | 13(S)-HODE (13(S)-hydroxyoctadecadienoic acid) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1uM, and down regulation of IRGpIIb/IIIa receptor expression. 13(S)-HODE methyl ester is a neutral, more lipophilic form of the free acid that can been used as an analytical standard for 13(S)-HODE. Group: Biochemicals. Grades: Highly Purified. CAS No. 109837-85-6. Pack Sizes: 100ug, 500ug. Molecular Formula: C19H34O3. US Biological Life Sciences. | Worldwide |
HZ-52 Quick inquiry Where to buy Suppliers range | A potent, reversible inhibitor of 5-lipoxygenase, blocking leukotriene synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes. It also attenuates leukotriene B4 synthesis, prevents carrageenan-induced pleurisy, and protects against platelet-activating factor-induced shock in mice when given intraperitoneally. Group: Biochemicals. Alternative Names: 2- [ [4- ( [1, 1'-biphenyl] -4-ylamino) -6-chloro-2-pyrimidinyl] thio] octanoic Acid; HZ 52. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |