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An intermediate in the synthesis of Epothilones. Epothilones are polyketid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 0.1mg. US Biological Life Sciences.
It is produced by the strain of L. fuscoatra. Synonyms: Benzoic acid, 2,4-dimethoxy-6-(2-oxoheptyl)-, 4-carboxy-3-methoxy-5-pentylphenyl ester; 2-O-Methylconfluentinsaeure. CAS No. 52213-25-9. Molecular formula: C29H38O8. Mole weight: 514.61.
2'-O-Methylhyperphyllinic acid A
2'-O-Methylhyperphyllinic acid A is a lichen depside. Synonyms: Benzoic acid, 2-hydroxy-4-methoxy-6-(2-oxononyl)-, 4-carboxy-3-methoxy-5-(2-oxoheptyl)phenyl ester; 4-Carboxy-3-methoxy-5-(2-oxoheptyl)phenyl 2-hydroxy-4-methoxy-6-(2-oxononyl)benzoate. CAS No. 193816-33-0. Molecular formula: C32H42O9. Mole weight: 570.67.
2'-O-Methylhyperphyllinic acid B
2'-O-Methylhyperphyllinic acid B is a lichen depside. Synonyms: Benzoic acid, 2-hydroxy-4-methoxy-6-(2-oxoheptyl)-, 4-carboxy-3-methoxy-5-(2-oxononyl)phenyl ester; 4-Carboxy-3-methoxy-5-(2-oxononyl)phenyl 2-hydroxy-4-methoxy-6-(2-oxoheptyl)benzoate. CAS No. 193816-31-8. Molecular formula: C32H42O9. Mole weight: 570.67.
3-Isopropenyl-6-oxoheptanal. Group: Biochemicals. Alternative Names: Limononaldehyde; 3-(1-Methylethenyl)-6-oxoheptanal. Grades: Highly Purified. CAS No. 7086-79-5. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C10H16O2. US Biological Life Sciences.
Worldwide
4-O-Methylhyperolivetoric acid
4-O-Methylhyperolivetoric acid is a lichen depside. Synonyms: β-Resorcylic acid, 6-heptyl-, 4-[2-hydroxy-6-(2-oxoheptyl)-p-anisate] (8CI). CAS No. 21251-07-0. Molecular formula: C29H38O8. Mole weight: 514.61.
4-O-Methylolivetoric acid
4-O-Methylolivetoric acid, as the principal secondary product, is a new depside of the new species Parmelia brattii Essl. from New Zealand. Synonyms: Benzoic acid, 2-hydroxy-4-[[2-hydroxy-4-methoxy-6-(2-oxoheptyl)benzoyl]oxy]-6-pentyl-. CAS No. 67093-46-3. Molecular formula: C27H34O8. Mole weight: 486.55.
A-factor
It is produced by the strain of streptomyces griseus. It can not only promote the formation of spores and air hyphae by streptomycin, but also restore the ability of non-production mutants to produce streptomycin, which is the so-called Autoregulator. Synonyms: 2-Isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone; Q27144309; SCHEMBL6026457; DTXSID00965600; 4-(HYDROXYMETHYL)-3-(6-METHYLHEPTANOYL)OXOLAN-2-ONE; 2(3H)-Furanone, dihydro-4-(hydroxymethyl)-3-(6-methyl-1-oxoheptyl)-, (4R)-; (-)-A factor; (R)-4-Hydroxymethyl-3-(6-methyl-heptanoyl)-dihydro-furan-2-one. CAS No. 51311-41-2. Molecular formula: C13H22O4. Mole weight: 242.31.
Atorvastatin-Amlodipine Adduct
Atorvastatin-Amlodipine Adduct is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: 3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate. CAS No. 425408-16-8. Molecular formula: C53H58ClFN4O9. Mole weight: 949.5.
Atorvastatin EP Impurity F
Atorvastatin EP Impurity F is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoic acid; Atorvastatin EP Impurity F; Atorvastatin calcium trihydrate impurity F [EP]; Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)-; (3R,5R)-7-((3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic acid; Atorvastatin diamino [USP impurity]; Atorvastatin amide. Grades: ≥95%. CAS No. 887196-24-9. Molecular formula: C40H48FN3O8. Mole weight: 717.82.
Atorvastatin Impurity F calcium salt
Atorvastatin Impurity F calcium salt. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic acid calcium salt. CAS No. 1105067-87-5. Molecular Formula: C40H47FN3O8·1/2Ca. Mole Weight: 736.87. Catalog: APB1105067875.
Caffezomib Impurity 56. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2S,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H59N5O8. Mole Weight: 737.93. Catalog: APB04726.
Caffezomib Impurity 57
Caffezomib Impurity 57. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2R,4S)-2-chloro-1-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H58ClN5O7. Mole Weight: 756.37. Catalog: APB04725.
Caffezomib Impurity 60
Caffezomib Impurity 60. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(1-((1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H59N5O8. Mole Weight: 737.93. Catalog: APB04721.
Caffezomib Impurity 61
Caffezomib Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2S,4S)-1-chloro-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H58ClN5O7. Mole Weight: 756.37. Catalog: APB04722.
Caffezomib Impurity 62
Caffezomib Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(1-((1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H59N5O8. Mole Weight: 737.93. Catalog: APB04720.
Carfilzomib Impurity 39
Carfilzomib Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2R,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. CAS No. 1541172-75-1. Molecular Formula: C40H59N5O8. Mole Weight: 737.93. Catalog: APB1541172751.
Carfilzomib Impurity 40
Carfilzomib Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((2R,4S)-1-((1H-benzo[d][1,2,3]triazol-1-yl)oxy)-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C46H62N8O8. Mole Weight: 855.03. Catalog: APB04736.
Carfilzomib Impurity 43
Carfilzomib Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-((S)-1-(((S)-2,6-dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. Molecular Formula: C40H57N5O6. Mole Weight: 703.91. Catalog: APB04734.
Cucurbitacin E
Cucurbitacin E is a natural compound which from Cucurbitaceae plants. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex. Group: Inhibitors. CAS No. 18444-66-1. Molecular formula: C32H44O8. Mole weight: 556.67. Appearance: White powder. Purity: 0.98. IUPACName: [(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate. Canonical SMILES: CC (=O)OC (C) (C)C=CC (=O)C (C) (C1C (CC2 (C1 (CC (=O)C3 (C2CC=C4C3C=C (C (=O)C4 (C)C)O)C)C)C)O)O. Catalog: ACM18444661.
Dehydrocollatolic acid is a depsidone from the Lichen Parmotrema nilgherrense. Synonyms: Spiro[2H,8H-[2]benzopyrano[5,6-b][1,4]benzodioxepin-2,2'-[2H]pyran]-4,8(1H)-dione, 3',4',5',6'-tetrahydro-5-hydroxy-11-methoxy-6'-methyl-9-(2-oxoheptyl)- (9CI); 3',4',5',6'-Tetrahydro-5-hydroxy-11-methoxy-6'-methyl-9-(2-oxoheptyl)spiro[2H,8H-[1,4]benzodioxepino[2,3-f][2]benzopyran-2,2'-[2H]pyran]-4,8(1H)-dione. CAS No. 350242-64-7. Molecular formula: C29H32O9. Mole weight: 524.56.
Des-Glu(3)-Semaglutide
Des-Glu(3)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Glu(9)-Semaglutide. Molecular formula: C182H284N44O56. Mole weight: 3984.53.
DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. Group: Others. Alternative Names: DT-2216; DT2216; DT 2216; DT2216 HCl. CAS No. 2365172-42-3. Molecular formula: C77H96ClF3N10O10S4. Mole weight: 1542.36. Appearance: Solid powder. Purity: >98%. IUPACName: (2S, 4R) -1- ( (S) -2- (7- (4- ( (R) -3- ( (4- (N- (4- (4- ( (4'-chloro-4, 4-dimethyl-3, 4, 5, 6-tetrahydro-[1, 1'-biphenyl]-2-yl) methyl) piperazin-1-yl) benzoyl) sulfamoyl) -2- ( (trifluoromethyl) sulfonyl) phenyl) amino) -4- (phenylthio) butyl) piperazin-1-yl) -7-oxoheptanamido) -3, 3-dimethylbutanoyl) -4-hydroxy-N- ( (S) -1- (4- (4-methylthiazol-5-yl) phenyl) ethyl) pyrrolidine-2-carboxamide. Canonical SMILES: CC1 (C) CCC (C2=CC=C (Cl) C=C2) =C (C1) CN3CCN (C4=CC=C (C (NS (=O) (C5=CC (S (C (F) (F) F) (=O) =O) =C (N[C@@H] (CSC6=CC=CC=C6) CCN7CCN (C (CCCCCC (N[C@@H] (C (C) (C) C) C (N8[C@@H] (C[C@@H] (O) C8) C (N[C@H] (C9=CC=C (C%10=C (N=CS%10) C) C=C9) C) =O) =O) =O) =O) CC7) C=C5)
EI-1511-3
It is produced by the strain of Streptomyces sp. E-1511. EI-1511-3 inhibited recombinant human ICE with an IC50 of 0.09 μmol/L. Synonyms: (2E,4E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-7-methylocta-2,4-dienamide. Molecular formula: C27H30N2O7. Mole weight: 494.54.
EI-1511-5
It is produced by the strain of Streptomyces sp. E-1511. EI-1511-5 inhibited recombinant human ICE with an IC50 of 0.38 μmol/L. Synonyms: (2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide. Molecular formula: C29H32N2O7. Mole weight: 520.57.
EI-1625-2
It is produced by the strain of Streptomyces sp. E-1625. EI-1625-2 inhibited recombinant human ICE with an IC50 of 0.2 μmol/L. Synonyms: (2E)-N-[(1S,5R,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-4-methyloct-2-enamide. Molecular formula: C27H32N2O7. Mole weight: 496.55.
Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the most well characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition. (Source: http://en. wikipedia. org/wiki/Ganoderic_acid). Group: Others. Alternative Names: (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid. CAS No. 81907-62-2. Molecular formula: C30H42O7. Mole weight: 514.65. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: C[C@H] (CC (=O)C[C@@H] (C)C (=O)O)[C@H]1C[C@@H] ([C@@]2 ([C@@]1 (CC (=O)C3=C2[C@H] (C[C@@H]4[C@@]3 (CCC (=O)C4 (C)C)C)O)C)C)O. Density: 1.22 g/ml. Catalog: ACM81907622.
Ganoderic Acid B
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease. Group: Inhibitors. CAS No. 81907-61-1. Molecular formula: C30H44O7. Mole weight: 516.7. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: CC (CC (=O)CC (C)C (=O)O)C1CC (=O)C2 (C1 (CC (=O)C3=C2C (CC4C3 (CCC (C4 (C)C)O)C)O)C)C. Catalog: ACM81907611.
Ganoderic acid D (GAD) is one of the major components in Ganoderma triterpenes. GAD treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with an IC(50) value of 17.3 +/- 0.3 microM. Synonyms: Ganoderic Acid D; 108340-60-9; GanodericacidD; Ganodernic acid D; SCHEMBL3676373; CHEMBL2205002; HY-N1511; BDBM50021402; AKOS032946021; MS-29559; CS-0017054; (6R)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 108340-60-9. Molecular formula: C30H42O7. Mole weight: 514.6.
Ganoderic acid I
Ganoderic acid I is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: 6-[(3S,5R,7S,10S,13R,14R,17S)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 98665-20-4. Molecular formula: C30H44O8. Mole weight: 532.674.
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: N-Acetyl-S-(4-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-5-methyl-3-oxoheptyl)-L-cysteine; N-acetyl-S- (4- (2- (2- (2- (hydroxyamino) -2-oxoethyl) heptanoyl) hexahydropyridazine-3-carboxamido) -5-methyl-3-oxoheptyl) -L-cysteine. CAS No. 140626-94-4. Molecular formula: C27H47N5O8S. Mole weight: 601.76.
Matlystatin D
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively. Synonyms: Matlystatin D1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140638-25-1. Molecular formula: C27H44N6O6. Mole weight: 548.68.
Matlystatin F
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively. Synonyms: Matlystatin F1; Pyrazolo(1,2-a)pyridazin-4-ium,5-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(5-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140667-42-1. Molecular formula: C27H44N6O6. Mole weight: 548.68.
Ono-1082 increases cAMP levels in hepatocytes in rats. Synonyms: Ono1082; Ono-1082; Ono 1082; N-(7-((1R,2R,3R)-2-((1E,3S)-3-((1S,3S)-3-Butylcyclopentyl)-3-hydroxy-1-propenyl)-3-hydroxy-5-oxocyclopentyl)-1,6-dioxoheptyl)-L-leucine;(2S)-2-[[7-[(2R,3R)-2-[(E,3S)-3-(3-butylcyclopentyl)-3-hydroxyprop-1-enyl]-3-hydroxy-5-oxocyclopentyl]-6-oxoheptanoyl]amino]-4-methylpentanoic acid;Ono1082;(S)-2-(7-((1R,2R,3R)-2-((S,E)-3-((1S,3S)-3-butylcyclopentyl)-3-hydroxyprop-1-en-1-yl)-3-hydroxy-5-oxocyclopentyl)-6-oxoheptanamido)-4-methylpentanoic acid. Grades: >98%. CAS No. 111111-04-7. Molecular formula: C30H49NO7. Mole weight: 535.72.
Polymyxin E2 Sulfate
It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt. Grades: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base).
Rosuvastatin 3-oxo impurity
Rosuvastatin 3-oxo impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate. CAS No. 1346606-28-7. Molecular Formula: C22H25FN3NaO6S. Mole Weight: 501.5. Catalog: APB1346606287.
Rosuvastatin EP Impurity C
Rosuvastatin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid. CAS No. 1422619-13-3. Molecular Formula: C22H26FN3O6S. Mole Weight: 479.52. Catalog: APB1422619133.
Rosuvastatin EP Impurity C (Calcium Salt)
Rosuvastatin EP Impurity C (Calcium Salt). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: calcium (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate. CAS No. 1422514-05-3. Molecular Formula: C22H25FN3O6S·1/2Ca. Mole Weight: 498.55. Catalog: APB1422514053.
Rosuvastatin EP Impurity C Sodium Salt
Rosuvastatin EP Impurity C Sodium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Synonyms: Rosuvastatin Impurity Sodium Salt; 5-Oxo Rosuvastatin Sodium Salt; Sodium (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate; (3R, 6E)-7-[4- (4-Fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic Acid Sodium Salt; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-, sodium salt (1:1), (3R,6E)-; (3R, 6E)-7-[4- (4-Fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl]-3-hydroxy-5-oxo-6-heptenoic acid sodium salt. Grades: ≥95%. CAS No. 1620823-61-1. Molecular formula: C22H25FN3NaO6S. Mole weight: 501.51.
Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90uM).1 At 8uM, salinomycin treatment of 4T1 and MCF7Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls.1 Treatment of 5mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells. Group: Biochemicals. Alternative Names: alpha-ethyl-6?[5-[2-(5-?ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,?10, 12-trimethyl-1, 6, 8-trioxadispiro[4. 1. 5. 3]pentadec-13-en-9-yl]-2-?hydroxy-1, ?3-dimethyl-4- oxoheptyl]tetrahydro-5-methyl-2H-pyran-2-acetic acid,? monosodium salt. Grades: Highly Purified. CAS No. 55721-31-8. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C42H69O11 Na, Molecular Weight: 773. US Biological Life Sciences.
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