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Trifluoroacetamidopropyl b-D-galactopyranoside is a renowned chemical compound extensively employed in the biomedical sector, serving for studying carbohydrate-protein interactions, particularly for maladies associated with carbohydrate metabolism.
1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trifluoroacetamido-D-glucopyranose is a vital compound in the biomedical industry. Widely used in drug development, it acts as a promising scaffold for designing potential antiviral and antibacterial agents due to its unique chemical structure. With its potential to inhibit specific enzymes and disrupt critical cellular functions, this compound shows promise for combating various infectious diseases and holds significant therapeutic potential in the biomedical field. Synonyms: Acetic acid 2,5-diacetoxy-6-acetomethyl-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-4-yl ester. CAS No. 7139-63-1. Molecular formula: C16H20F3NO10. Mole weight: 443.33.
1,3-Diethyl 2- (2, 2, 2-trifluoroacetamido) propanedioate. Group: Biochemicals. Grades: Highly Purified. CAS No. 76699-09-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H12F3NO5, Molecular Weight: 271.19. US Biological Life Sciences.
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14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt
14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt is an intermediate in the synthesis of Doxorubicin Dimer Impurity 1which is an is an impurity of Doxorubicin Hydrochloride (D558000), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C29H27BrF3NO11. US Biological Life Sciences.
2-Deoxy-2-trifluoroacetamido-D-glucose, an indispensable compound within the biomedical sector, manifests noteworthy potential in thwarting glycosylation. Its ubiquitous application spans diabetes, cancer, and other glycosylation-associated ailments. By impeding glucose metabolism, it engenders unprecedented therapeutic avenues for patients grappling with these afflictions. Synonyms: N-Trifluoroacetyl-D-glucosamine 2-Deoxy-2-trifluoroacetamido-D-glucopyranose. CAS No. 36875-26-0. Molecular formula: C8H12F3NO6. Mole weight: 275.18.
2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine
2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a biomedical product used in the research of viral infections and cancer. It acts as an antiviral and antitumor agent, targeting viral RNA and inhibiting tumor cell proliferation. Derived from uridine, this compound shows potential in nucleoside analog therapy due to its ability to selectively target infected or cancerous cells while minimizing toxicity to healthy cells. Molecular formula: C32H30F3N3O8. Mole weight: 641.61.
3,4,6-Tri-O-acetyl-2-deoxy-2-trifluoroacetamido-b-D-glucopyranosyl fluoride, an extraordinary biomedical compound, stands as a burgeoning solution in combatting diverse maladies. With its remarkable capabilities, this product exhibits unrivaled potential as a powerful inhibitor of specific enzymes, rendering it invaluable for pioneering drug discovery endeavors aimed at combating resilient pathogens. Synonyms: [(2R,3S,4R,5R,6S)-3,4-Diacetyloxy-6-fluoro-5-[(2,2,2-trifluoroacetyl)amino]oxan-2-yl]methyl acetate; 2-Trifluroacetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranosyl Fluoride; (2R,3S,4R,5R,6S)-2-(Acetoxymethyl)-6-fluoro-5-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-3,4-diyl diacetate; 3,4,6-Tri-O-acetyl-2-deoxy-2-trifluoroacetamido-b-D-glucopyranosyl fluoride; 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-D-glucopyranosyl bromide?; 2-Trifluroacetamido-3,4,6-tri-O-acetyl-2-deoxy-?-D-glucopyranosyl Fluoride; 2-Trifluroacetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl Fluoride; (2R,3S,4R,5R,6S)-2-(Acetoxymethyl)-6-fluoro-5-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-3,4-diyldiacetate. CAS No. 137686-91-0. Molecular formula: C14H17F4NO8. Mole weight: 403.28.
4-Methylumbelliferyl 3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-a-D-glucopyranoside, a chemical compound widely employed in the biomedical industry, exhibits remarkable versatility in numerous applications. This compound, esteemed for its indispensability, finds significant utility in drug discovery and development processes, primarily serving as an essential substrate for enzymatic activity assays. Its unparalleled efficacy in detecting and quantifying glucosidases propels the advancement of pharmaceutical research. Synonyms: 4-Methylumbelliferyl3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-a-D-glucopyranoside; [(2R,3S,4R,5R,6R)-3,4-diacetyloxy-6-(4-methyl-2-oxochromen-7-yl)oxy-5-[(2,2,2-trifluoroacetyl)amino]oxan-2-yl]methyl acetate; (2R,3S,4R,5R,6R)-2-(Acetoxymethyl)-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)-5-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-3,4-diyl diacetate; 4-METHYLUMBELLIFERYL 2-TRIFLUOROACETYL-3,4,6-O-TRIACETYL-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE; MGLRSUPYLXVODY-FYKMYLNBSA-N; 2-Nitrophenyl b-D-glucuronide; DTXSID00745388; 4-Methylumbelliferyl 2-Trifluoroacetyl-3,4,6-O-triacetyl-2-deoxy-?-D-glucopyranoside; 4-Methylumbelliferyl 3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-a-D-glucopyranoside; W-201159; [(2R,3S,4R,5R,6R)-3,4-bis(acetyloxy)-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]-5-(2,2,2-trifluoroacetamido)oxan-2-yl]methyl acetate; 4-Methyl-2-oxo-2H-1-benzopyran-7-yl 3,4,6-tri-O-acetyl-2-deoxy-2-(2,2,2-trifluoroacetamido)-alpha-D-glucopyranoside. CAS No. 137686-92-1. Molecular formula: C24H24F3NO11. Mole weight: 559.44.
4-Methylumbelliferyl 3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-b-D-glucopyranoside, a highly intricate and specialized compound, serves as an invaluable tool in the realm of biomedical research. Specifically designed to evaluate the functionality of various enzymes, this substrate offers profound insights into their activity. Upon encountering specific enzymes, it undergoes hydrolysis, liberating an illuminating fluorescent entity known as 4-Methylumbelliferone. The ensuing fluorescence can be diligently quantified, enabling precise measurements. Synonyms: 4-Methylumbelliferyl 3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-b-D-glucopyranoside; (2R,3S,4R,5R,6S)-2-(Acetoxymethyl)-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)-5-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-3,4-diyl diacetate; [(2R,3S,4R,5R,6S)-3,4-diacetyloxy-6-(4-methyl-2-oxochromen-7-yl)oxy-5-[(2,2,2-trifluoroacetyl)amino]oxan-2-yl]methyl acetate; 4-Methylumbelliferyl 2-Trifluoroacetyl-3,4,6-O-triacetyl-2-deoxy-beta-D-glucopyranoside. CAS No. 137686-93-2. Molecular formula: C24H24F3NO11. Mole weight: 559.44.
4-N-Trifluoroacetamidophenyl 2-azido-2-deoxy-α-D-galactopyranoside, an indispensable biomedical asset, finds extensive application in the realm of novel antiviral therapeutics. Facilitating assessment of potential remedies targeting viral infections such as HIV and herpes, its unparalleled molecular framework stands as a remarkable tool for drug investigation and scientific exploration. CAS No. 210426-03-2. Molecular formula: C14H15F3N4O6. Mole weight: 392.29.
5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine
5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine is used in the biomedical industry for its potential role in studying viral diseases. It may have antiviral properties due to the presence of uridine derivatives and the trifluoroacetamido group. Synonyms: N-((E)-3-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)-2,2,2-trifluoroacetamide; 5-TFA-aa-uridine; 5-TFA-aa-U; (E)-5-[3-(Trifluoroacetamido)-1-propenyl]uridine; 5-{(1E)-3-[(Trifluoroacetyl)amino]-1-propen-1-yl}uridine. Grades: ≥98% by HPLC. CAS No. 869222-68-4. Molecular formula: C14H16F3N3O7. Mole weight: 395.29.
5-[3-(Trifluoroacetamido)-E-1-propenyl]-2'-deoxyuridine is a potent antiviral agent utilized in the treatment of viral infections caused by herpes simplex viruses (HSV-1, HSV-2), varicella-zoster virus (VZV), and Epstein-Barr virus (EBV). This compound inhibits viral DNA replication, reducing viral propagation and promoting host recovery. Its mechanism of action involves the incorporation into viral DNA, leading to chain termination. Synonyms: 5-TFA-aa-2'-deoxyuridine; TFA-aa-dU; 2'-Deoxy-5-[(1E)-3-[(trifluoroacetyl)amino]-1-propen-1-yl]uridine; (E)-2'-Deoxy-5-[3-[(trifluoroacetyl)amino]-1-propenyl]-uridine; 2'-Deoxy-5-[(1E)-3-[(trifluoroacetyl)amino]-1-propenyl]-uridine; TFA-AA-2'-deoxyuridine. Grades: ≥98% by HPLC. CAS No. 115794-55-3. Molecular formula: C14H16F3N3O6. Mole weight: 379.29.
5-[N(2-(Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2'-deoxyuridine is a potent anti-cancer compound with the ability to inhibit DNA enhancement. This compound facilitates the research of diseases such as leukemia, breast cancer and lung cancer by impeding tumor growth and promoting cell death. Synonyms: (E)-3-[1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-N-[2-[(2,2,2-trifluoroacetyl)amino]ethyl]prop-2-enamide. Grades: 95%. CAS No. 869222-69-5. Molecular formula: C16H19F3N4O7. Mole weight: 436.36.
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine, known for its potent antiviral properties, has become a pivotal component in research of combatting viral infections induced by herpes simplex viruses (HSV). Functionally, it obtrudes viral DNA replication by inducing chain termination throughout the process of viral DNA research and development. Synonyms: 5-TFA-aha-2'-deoxyuridine; TFA-aha-dU; 2'-Deoxy-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-uridine; 5-TFA-aha-dU; uridine, 2'-deoxy-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-; (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide. Grades: ≥98% by HPLC. CAS No. 252337-58-9. Molecular formula: C20H27F3N4O. Mole weight: 396.45.
5'-O-(Dimethoxytrityl)-5-[N-(2-(trifluoroacetamido)ethyl)-3-(E)acrylamido]-2'-deoxyuridine is a crucial compound in biomedicine used for the development of antiviral drugs. With its unique chemical structure, it exhibits activity against a variety of viral infections, including DNA viruses, RNA viruses, and retroviruses. This product plays a pivotal role in the synthesis of potent antiviral medication, contributing to the treatment and prevention of numerous viral diseases. Synonyms: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-N-[2-[(2,2,2-trifluoroacetyl)amino]ethyl]prop-2-enamide; 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine; 5/'-O-(DIMETHOXYTRITYL)-5-[N-(2-(TRIFLUOROACETAMIDO)ETHYL)-3-(E)-ACRYLAMIDO]-2/'-DEOXYURIDINE; (E)-3- (1- ( (2R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)-N- (2- (2, 2, 2-trifluoroacetamido)ethyl)acrylamide; 5'-o-(Dimethoxytrityl)-5-[N-(2-(trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2'-decxyuridine. Grades: ≥ 97%. CAS No. 153512-23-3. Molecular formula: C37H37F3N4O9. Mole weight: 738.73.
The 5'-O-(Dimethoxytrityl)-5-[N-(6-(trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine represents a pivotal compound utilized in the field of biomedicine due to its indispensable role in the synthesis and advancement of potential antiviral agents. By specifically targeting viral replication processes and crucial enzymes, this product exhibits considerable promise in the treatment of a diverse range of viral infections. Thus, it assumes a vital role in the progression of pharmaceutical research, offering prospective solutions for tackling various viral diseases with utmost efficacy. Synonyms: 5'-DMT-5-TFA-aha-2'-deoxyuridine; 5'-DMT-5-TFA-aha-dU; 5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acryamido]-2'-deoxyuridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-Uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]uridine. Grades: ≥98% by HPLC. CAS No. 252337-59-0. Molecular formula: C41H45F3N4O9. Mole weight: 794.84.
5'-O-Dimethoxytrityl-N2-(trifluoroacetamido)hexyl-2'-deoxyguanosine, a nucleoside analog, finds extensive application in the biomedical research and drug development as it is widely used for the synthesis of oligonucleotides. Thanks to its unique abilities to trigger cell death and hinder DNA replication, it has garnered significant attention for its suitability in treating cancer and viral infections. Intriguingly, recent findings suggest it may prove efficacious in targeting malignant cells exclusively, while safeguarding healthy cells against damage, thus holding immense promise as a cancer treatment of the future. Grades: ≥ 95%. Molecular formula: C39H43F3N6O7. Mole weight: 764.80.
5'-O-DMT-5-[N- (6- (trifluoroacetamido) hexyl) -3-E-acryamido]-2'-deoxyuridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 252337-59-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C41H45F3N4O9. US Biological Life Sciences.
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5'-Trifluoroacetamido-5'-deoxythymidine
5'-Trifluoroacetamido-5'-deoxythymidine is an exceedingly efficacious antiviral entity, demonstrating immense potential for the research of DNA virus-mediated detrimental infections, primarily those affiliated with herpesviruses. The discerning mode of action revolves around the selective suppression of viral DNA replication through specific antagonism of viral thymidine kinase, a critical and indispensible enzyme driving viral DNA enhancement. Synonyms: 2,2,2-Trifluoro-N-(((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)acetamide; 5'-Deoxy-5'-(2,2,2-trifluoroacetamido)thymidine. Grades: 95%. CAS No. 55812-00-5. Molecular formula: C12H14F3N3O5. Mole weight: 337.26.
Allyl 2-deoxy-4,6-O-isopropylidene-2-(trifluoroacetamido)-a-D-glucopyranoside is a crucial compound within the biomedical sector, exhibiting immense application for drug innovation. Synonyms: N-[(4aR,6S,7R,8R,8aS)-8-hydroxy-2,2-dimethyl-6-prop-2-enoxy-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]-2,2,2-trifluoroacetamide; 1-o-Allyl-2-deoxy-4,6-o-isopropylidene-2-(trifluoroacetamido)-alpha-D-gluco-pyranoside; a-D-Glucopyranoside,2-propen-1-yl2-deoxy-4,6-O-(1-methylethylidene)-2-[(2,2,2-trifluoroacetyl)amino]-; N-((4AR,6S,7R,8R,8aS)-6-(allyloxy)-8-hydroxy-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)-2,2,2-trifluoroacetamide; Prop-2-en-1-yl 2-deoxy-4,6-O-(1-methylethylidene)-2-(2,2,2-trifluoroacetamido)-alpha-D-glucopyranoside. CAS No. 139629-59-7. Molecular formula: C14H20F3NO6. Mole weight: 355.31.
Dichloro[1, 3-bis (2, 4, 6-trimethylphenyl) -2-imidazolidinylidene][ (2-isopropoxy) (5-trifluoroacetamido) benzylidene]ruthenium (II)
Ruthenium Catalysts. CAS No. 1025728-56-6. Mole weight: 737.64. Catalog: ACM1025728566.
N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine, a remarkable antiviral agent, is extensively employed in the biomedicine sector. Its extraordinary capacity to combat a diverse array of DNA and RNA viruses, notably HIV and hepatitis, positions it as a compelling choice for treating viral infections. With its distinctive chemical composition and mechanism of action, this compound holds immense potential in the exploration of novel antiviral therapies, making it a key focus of research within the scientific community. Molecular formula: C39H35F3N4O8. Mole weight: 744.71.
2,2,2-Trifluoro-N-4-pyridinyl-acetamide. Group: Biochemicals. Alternative Names: 4- (Trifluoroacetamido) pyridine. Grades: Highly Purified. CAS No. 77262-39-6. Pack Sizes: 500mg. US Biological Life Sciences.
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2,2,2-Trifluoro-N-4-pyridinyl-acetamide N-Oxide
2,2,2-Trifluoro-N-4-pyridinyl-acetamide N-Oxide. Group: Biochemicals. Alternative Names: 4- (Trifluoroacetamido) pyridine N-Oxide. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
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2'-TFA-NH-2'-Deoxyuridine
2'-TFA-NH-2'-Deoxyuridine is a nucleoside analogue that has been used to treat certain viral infections and cancers. It is incorporated into the DNA of the target cells, causing chain termination and preventing further replication. Its antiviral activity has been observed against herpes simplex virus types 1 and 2, as well as varicella zoster virus. It has also shown promise in slowing the growth of certain tumors. Synonyms: 2'-TFA-NH-dU; 2'-trifluoroacetamido-2'-deoxyuridine; Uridine, 2'-deoxy-2'-[(trifluoroacetyl)amino]-; 2'-Deoxy-2'-[(trifluoroacetyl)amino]uridine; Uridine, 2'-deoxy-2'-[(2,2,2-trifluoroacetyl)amino]-; N-((2R,3R,4S,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)-2,2,2-trifluoroacetamide. Grades: ≥97% by HPLC. CAS No. 51989-21-0. Molecular formula: C11H12F3N3O6. Mole weight: 339.22.
2'-TFA-NH-dA
2'-TFA-NH-dA is a meticulously engineered nucleoside, it boasts an unparalleled capacity for seamless assimilation within nucleic acids and DNA chains. Crucially, this remarkable compound unfurls as an indispensable instrument in the comprehensive examination and research of DNA-associated afflictions. Synonyms: 2'-TFA-NH-2'-Deoxyadenosine; 2'-deoxy-2'-trifluoroacetamidoadenosine; Adenosine, 2'-deoxy-2'-[(2,2,2-trifluoroacetyl)amino]-; 2'-Deoxy-2'-[(trifluoroacetyl)amino]adenosine; N-((2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)-2,2,2-trifluoroacetamide. Grades: ≥97% by HPLC. CAS No. 182626-53-5. Molecular formula: C12H13F3N6O4. Mole weight: 362.26.
2'-TFA-NH-dC
2'-TFA-NH-dC, commonly known as 2'-trifluoroacetamido-2'-deoxycytidine, stands as a fundamental compound profoundly employed in the realm of biomedicine. Esteemed for its invaluable contributions, this product assumes a pivotal position in the creation of nucleotide analogs, crucial for combating a myriad of viral infections and malignancies. Through its indispensability as a principal constituent in the fabrication of targeted chemotherapeutics and antiviral medications, it fosters unprecedented progress in the field of biomedical exploration and pharmaceutical innovation. Synonyms: 2'-TFA-NH-2'-Deoxycytidine; 2'-Deoxy-2'-[(trifluoroacetyl)amino]cytidine; Cytidine, 2'-deoxy-2'-[(2,2,2-trifluoroacetyl)amino]-. Grades: ≥97% by HPLC. CAS No. 84715-67-3. Molecular formula: C11H13F3N4O5. Mole weight: 338.24.
Intermediate in the production of Folic Acid. Group: Biochemicals. Alternative Names: 4-[ (2, 2, 2-Trifluoroacetyl) amino]benzoic Acid; p- (Trifluoroacetamido) benzoic Acid; NSC 150503. Grades: Highly Purified. CAS No. 404-26-2. Pack Sizes: 250mg. US Biological Life Sciences.
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4- (Trifluoroacetylamino) benzoic Acid-d4
Intermediate in the production of labeled Folic Acid. Group: Biochemicals. Alternative Names: 4-[ (2, 2, 2-Trifluoroacetyl) amino]benzoic Acid-d4; p- (Trifluoroacetamido) benzoic Acid-d4; NSC 150503-d4. Grades: Highly Purified. CAS No. 461426-32-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-[3-(Trifluoroacetyl)aminopropyn-1-yl]uridine
5-[3-(Trifluoroacetyl)aminopropyn-1-yl]uridine, a highly potent antiviral agent, finds extensive usage in the biomedical sector. Its remarkable efficacy is attributed to its ability to impede viral RNA replication and halt viral dissemination, thereby combatting notorious viral infections like hepatitis C and herpes simplex. Synonyms: 5-(3-trifluoroacetamidopropyn-1-yl)-uridine; 5-[3-(Trifluoroacetylamino)-1-propynyl]uridine; Uridine, 5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]-; N-{3-[1-((3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-prop-2-ynyl}-2,2,2-trifluoro-acetamide. Grades: ≥95%. CAS No. 120609-05-4. Molecular formula: C14H14F3N3O7. Mole weight: 393.27.
5'-Amino-Modifier TEG CE-Phosphoramidite
5'-Amino-Modifier TEG CE-Phosphoramidite is a chemical reagent commonly used in oligonucleotide synthesis. It is used to introduce an amino group at the 5' end of DNA or RNA sequences. This modification can be used to conjugate the oligonucleotide to other molecules, such as drugs, and to attach it to solid supports for use in diagnostic assays. The TEG spacer provides increased solubility and flexibility, while the CE-phosphoramidite group allows for facile incorporation during synthesis. Synonyms: 10-(O-trifluoroacetamido-N-ethyl)-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C19H35F3N3O6P. Mole weight: 489.47.
5-[N-(6-(Trifluoroacetamido)hexyl)-(E)-acrylamido]uridine is a highly intricate compound with antiviral capability, presenting itself as a potent research option for prevailing viral infections like influenza, hepatitis C is and respiratory syncytial virus. Synonyms: 5-[3-OXO-3-[[6-[TRIFLUORACETYLAMINO]HEXYL]AMINO]-1-PROPENYL]URIDINE. CAS No. 869222-70-8. Molecular formula: C20H27F3N4. Mole weight: 508.46.
5-TFA-ap-2',3'-Dideoxycytidine
5-TFA-ap-2',3'-Dideoxycytidine, a nucleoside analogue implemented as an antiviral agent to counteract human immunodeficiency virus (HIV) infections, functions by obstructing the reverse transcriptase enzyme crucial for viral replication. Its utilization as a potent antiviral compound has been studied extensively due to its promising therapeutic capabilities in restraining the detrimental spread of HIV. Synonyms: 5-[(Trifluoracetyl)amino]propynyl-ddC; 5-TFA-ap-ddC; 2',3'-Dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-cytidine; Cytidine, 2',3'-dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-; 5-(3-Trifluoroacetamido-1-propynyl)-2',3'-dideoxycytidine; N-(3-{4-Amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-2-oxo-1,2-dihydro-5-pyrimidinyl}-2-propyn-1-yl)-2,2,2-trifluoroacetamide. Grades: ≥97% by HPLC. CAS No. 114748-58-2. Molecular formula: C14H15F3N4O4. Mole weight: 360.29.
5-TFA-ap-2',3'-Dideoxyuridine
5-TFA-ap-2',3'-Dideoxyuridine is an exceptionally potent antiviral compound extensively used in the research of viral infections, especially the ones attributed to DNA viruses. Its outstanding efficacy lies in its ability to thwart viral DNA enhancement, thereby effectively curbing viral replication and averting the pernicious expansion of the viral affliction. Synonyms: 5-[(Trifluoracetyl)amino]propynyl-ddU; 5-(3-trifluoroacetamido-1-propynyl)-2',3'-dideoxyuridine; 2',3'-Dideoxy-5-[3-(trifluoroacetylamino)-1-propynyl]uridine; Uridine, 2',3'-dideoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-; 5-TFA-AP-DDU; 2,2,2-Trifluoro-N-(3-{1-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl}-2-propyn-1-yl)acetamide. Grades: ≥97% by HPLC. CAS No. 114748-60-6. Molecular formula: C14H14F3N3O5. Mole weight: 361.27.
AP-dC-CE Phosphoramidite
AP-dC-CE Phosphoramidite is an invaluable reagent utilized within the fascinating realm of medicinal chemistry for synthesizing oligonucleotide prodrugs with great precision. This remarkable compound is frequently employed within cutting-edge drug design, enabling the targeted delivery of therapeutic agents to specific cells or tissues - a fundamental approach for treating an array of diseases ranging from cancer and viral infections to complex genetic disorders. Synonyms: 1-[5'-O-(4,4'-Dimethoxytrityl)-β-D-2'-deoxyribofuranosyl]-9-(2-trifluoroacetamidoethoxy)-1,3-diaza-2-oxophenoxazine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite. Molecular formula: C49H54F3N6O10P. Mole weight: 974.97.
Boc-Lys(Tfa)-AMC
Boc-Lys(Tfa)-AMC is a fluorogenic substrate for the assaying of histone deacetylase (HDAC) 4, 5 and 7 activity in a protease-coupled assay. Synonyms: tert-butyl N-[(2S)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxo-6-[(2,2,2-trifluoroacetyl)amino]hexan-2-yl]carbamate; (S)-tert-Butyl (1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxo-6-(2,2,2-trifluoroacetamido)hexan-2-yl)carbamate; Boc-L-Lys-MCA; Boc L Lys MCA. Grades: 98%. CAS No. 97885-44-4. Molecular formula: C23H28F3N3O6. Mole weight: 499.49.
Daunorubicin Impurity 14
Daunorubicin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4S,5S,6S)-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2,5-diyl bis(4-nitrobenzoate). Molecular Formula: C22H18F3N3O10. Mole Weight: 541.39. Catalog: APB05531.
(-)-Inosine Dehydroxy-N-(6-iminohexyl)-2,2,2-trifluoroacetamide Phosphate is an intermediate in synthesizing N6-(6-Aminohexyl)-FAD, a Flavine Adenine Dinucleotide (FAD) derivative. Attachment of a ligand to the 6-Aminohexyl side chain of this compound, can be used as a FAD-labelled conjugate to measure the concentration of the free ligand in a competitive binding immunoassay. Synonyms: ((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-((6-(2,2,2-trifluoroacetamido)hexyl)amino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl Dihydrogen Phosphate. Molecular formula: C18H26F3N6O8P. Mole weight: 542.4.
(-)-Inosine Dehydroxy-N-(6-iminohexyl)-2,2,2-trifluoroacetamide Phospho-morpholine is an intermediate in synthesizing N6-(6-Aminohexyl)-FAD, a derivative of Flavine Adenine Dinucleotide (FAD). Synonyms: ((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-((6-(2,2,2-trifluoroacetamido)hexyl)amino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl Morpholino Hydrogen Phosphate. Molecular formula: C22H33F3N7O9P. Mole weight: 627.51.
Lisinopril Impurity 15
Lisinopril Impurity 15 is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: L-Lysine, N2-(2,2,2-trifluoroacetyl)-; trifluoroacetyl-L-lysine; trifluoroacetyl-lysine; n-trifluoroacetyllysine; N-trifluoroacetyl L-lysine; N-trifluoroacetyl-L-lysine; SCHEMBL287360; DTXSID101293299; CCG-233201; N2-(2,2,2-Trifluoroacetyl)-L-lysine; EN300-7034155; (2S)-6-amino-2-(trifluoroacetamido)hexanoic acid; BRD-K54317024-001-01-8. CAS No. 21761-08-0. Molecular formula: C8H13F3N2O3. Mole weight: 242.20.
Methyl N-trifluoroacetyldaunosaminide
Methyl N-Trifluoroacetyldaunosaminide is an intermediate in the production of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: Methyl 2,3,6-Trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-L-lyxo-hexopyranoside; methyl 2,3,6-trideoxy-3-(trifluoroacetamido)-L-lyxo-hexopyranoside; 1-O-Methyl-2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-L-lyxo-hexopyranose. Grades: ≥95%. CAS No. 51996-41-9. Molecular formula: C9H14F3NO4. Mole weight: 257.21.
MK0686
MK0686 is a bradykinin B1 receptor antagonist. It exhibits suitable pharmacokinetic properties and efficient ex vivo receptor occupancy for further development as a novel approach for the treatment of pain and inflammation. It had been in phase II clinical trials by Merck Sharp & Dohme for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. But it is discontinued now. Uses: Mk0686 is used for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. Synonyms: MK0686; MK 0686; MK-0686;Methyl 2-chloro-6- [3-fluoro-4- [ (1R) -1- [ [1- [ (2, 2, 2-trifluoroacetyl) amino] cyclopropanecarbonyl] amino] ethyl] phenyl] benzoate; Methyl (R)-3-chloro-3'-fluoro-4'-(1-(1-(2,2,2-trifluoroacetamido)cyclopropane-1-carboxamido)ethyl)-[1,1'-biphenyl]-2-carboxyla. Grades: 98%. CAS No. 578727-68-1. Molecular formula: C22H19ClF4N2O4. Mole weight: 486.85.
Doxorubicin metabolite. Cytotoxic interaction with DNA. Group: Biochemicals. Alternative Names: N-tri fluoroacetyl adriamycin; NSC 283464; (8S-cis) -7, 8, 9, 10-Tetrahydro-6, 8, 11-trihydroxy-8- (hydroxyacetyl) -1-methoxy-10-[[2, 3, 6-trideoxy-3-[ (trifluoroacetyl) amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione; (1S,3S)- α-2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-3-glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl L-lyxo-Hexopyranoside. Grades: Highly Purified. CAS No. 26295-56-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Trifluoroacetyl Doxorubicin
N-Trifluoroacetyl Doxorubicin is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: N-Trifluoroacetyladriamycin; NSC 283464; (8S-cis)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione; (1S,3S)-α-2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-3-glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl L-lyxo-Hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-. Grades: >95%. CAS No. 26295-56-7. Molecular formula: C29H28F3NO12. Mole weight: 639.53.
PF-07321332
Nirmatrelvir, also known as PF-07321332 (brand name: Paxlovid), is an orally bioavailable 3C-like protease (3CLPRO) inhibitor and SARS-CoV-2 Mpro inhibitor. This drug is being investigated for safety, tolerability, and pharmacokinetics before moving on to studies of efficacy in the treatment or prophylaxis of COVID-19. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. PF-07321332 is an oral COVID-19 antiviral clinical candidate. By inhibiting the main protease, PF-07321332 prevents the virus from cleaving long protein chains into the parts it needs to reproduce itself. Group: Inhibitors. Alternative Names: Nirmatrelvir; PF-07321332; PF 07321332; PF07321332; brand name Paxlovid. CAS No. 2628280-40-8. Molecular formula: C23H32F3N5O4. Mole weight: 499.54. Appearance: Solid powder. Purity: >98%. IUPACName: (1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide. Canonical SMILES: [H][C@]12CN ([C@H] (C (=O)N[C@@H] (C[C@]3 ([H])CCNC3=O)C#N)[C@@]1 ([H])C2 (C)C)C (=O)[C@@H] (NC (=O)C (F) (F)F)C (C) (C)C. Catalog: ACM2628280408.
TFA-Hexylaminolinker Phosphoramidite
TFA-Hexylaminolinker Phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: TFA-aminolinker C6 phosphoramidite; 2-Cyanoethyl (6-(2,2,2-trifluoroacetamido)hexyl) diisopropylphosphoramidite; 6-(N-Trifluoroacetamido)hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: ≥90%. CAS No. 133975-85-6. Molecular formula: C17H31F3N3O3P. Mole weight: 413.42.