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| Product | Description | |
|---|---|---|
| Taribavirin | Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 119567-79-2. Molecular formula: C8H13N5O4. Mole weight: 243.2217. Canonical SMILES: N=C(C1=NN([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)O)C=N1)N. Product ID: ACM119567792. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Taribavirin hydrochloride | Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A. |  |
| Tariquidar | Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XR9576. CAS No. 206873-63-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10550. | |
| Tariquidar | Tariquidar. Uses: Designed for use in research and industrial production. CAS No. 206873-63-4. Molecular formula: C38H38N4O6. Mole weight: 646.73. Purity: 0.98. Product ID: ACM206873634. Alfa Chemistry ISO 9001:2015 Certified. | |
| Tariquidar | Tariquidar. Group: Biochemicals. Alternative Names: N- [2- [ [ [4- [2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl] phenyl] amino] carbonyl] -4, 5-dimethoxyphenyl] -3-quinolinecarboxamide; XR 9576. Grades: Highly Purified. CAS No. 206873-63-4. Pack Sizes: 25mg. Molecular Formula: C38H38N4O6, Molecular Weight: 646.73. US Biological Life Sciences. |  Worldwide |
| Tariquidar | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| Tariquidar | Tariquidar, also known as XR9576, is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Synonyms: XR 9576; XR9576; XR-9576; D06008. Grades: >98%. CAS No. 206873-63-4. Molecular formula: C38H38N4O6. Mole weight: 646.744. |  |
| Tariquidar-d4 | Tariquidar-d4. Group: Biochemicals. Alternative Names: N- [2- [ [ [4- [2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl] phenyl] amino] carbonyl] -4, 5-dimethoxyphenyl] -3-quinolinecarboxamide-d4; XR 9576-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C38H34D4N4O6, Molecular Weight: 650.76. US Biological Life Sciences. | Worldwide |
| Tariquidar dihydrochloride | Tariquidar dihydrochloride is a potent P-glycoprotein (P-gp) inhibitor (IC50 = 5.1 nM). Tariquidar was found to reverse drug resistance in multiple MDR cell lines. Tariquidar binds to the p-glycoprotein transporter, and inhibits transmembrane transport of anticancer drugs, leading to increased concentrations and enhanced cytotoxic effects of anticancer drugs. Synonyms: N-[2-[[[4-[2- (3, 4-dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]amino]carbonyl]-4, 5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1992047-62-7. Molecular formula: C38H38N4O6.2HCl. Mole weight: 719.66. | |
| Tariquidar methanesulfonate hydrate | Tariquidar methanesulfonate is a potent and selective noncompetitive inhibitor of P-glycoprotein(Kd =5.1 nM). Uses: P-glycoprotein inhibitor, potent and selective. Synonyms: XR 9576; XR9576; XR-9576;N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide;methanesulfonic acid;trihydrate. Grades: ≥98%. CAS No. 625375-83-9. Molecular formula: C40H52N4O15S2. Mole weight: 892.99. | |
| Tariquidar methanesulfonate, hydrate | Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a Kd of 5.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XR9576 methanesulfonate, hydrate. CAS No. 625375-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10550A. | |
| Tarlatamab | Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the K D s of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the K D s of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-757. CAS No. 2307488-83-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99575. | |
| Tarloxotinib bromide | Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-4000. CAS No. 1636180-98-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17632. | |
| Tarloxotinib bromide | Tarloxotinib bromide, a pyridopyrimidine derivative, has been found to be a EGFR tyrosine kinase inhibitor precursor and could probably be effective in antineoplastic researches. Synonyms: Tarloxotinib bromide; Tarloxotinib bromide [INN]; SCHEMBL11902818; SCHEMBL17873943; [(E)-4-[[4-(3-bromo-4-chloroanilino)pyrido[3,4-d]pyrimidin-6-yl]amino]-4-oxobut-2-enyl]-dimethyl-[(3-methyl-5-nitroimidazol-4-yl)methyl]azanium;bromide. Grades: 98%. CAS No. 1636180-98-7. Molecular formula: C24H24Br2ClN9O3. Mole weight: 681.77. | |
| Tarocin A1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Taro Powder | Taro Powder. Group: Others. Taro Powder; Colocasia esculenta (L).Schott. Cat No: EXTC-113. |  |
| Tartaric acid | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Tartaric Acid | Tartaric Acid. CAS No. 87-69-4. Molecular Formula HOOC(CHOH)2COOH. Chemical Reagents |  Cater Chemicals Corp. Illinois IL |
| Tartaric Acid | Tartaric Acid. Category ACIDS. Pack Sizes Drums/ bags/ bulk |  |
| Tartaric Acid | Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder. It is odorless, with an extremely tart taste. Synonyms: Acidum tartaricum; L-(+)-2 , 3-dihydroxybutanedioic acid; (2R, 3R)- dihydroxybutane-1, 4-dioic acid; d- tartaric acid; 2 , 3-dihydroxysuccinic acid; L-(+)- tartaric acid. CAS No. 87-69-4. Product ID: PE-0449. Molecular formula: C4H6O6. Mole weight: 150.09. Category: Effervescents. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Tartaric Acid; Effervescents; Effervescents; C4H6O6; 87-69-4; 87-69-4. UNII: W4888I119H. Chemical Name: (2R, 3R)-2, 3-Dihydroxybutanedioic acid. Administration route: IM and IV; oral; sublingual; topical; rectal and vaginal. Dosage Form: IM and IV injections; oral solutions, syrups and tablets; sublingual tablets; topical films; rectal and vaginal preparations. Stability and Storage Conditions: The bulk material is stable and should be stored in a well-closed container in a cool, dry place. Source and Preparation: Tartaric acid occurs naturally in many fruits as the free acid or in combination with calcium, magnesium, and potassium. Commercially, L-(+)-tartaric acid is manufactured from potassium tartrate (cream of tartar), a by-product of wine making.Potassium tartrate is treated with hydrochloric acid, followed by the addition of a calcium salt to produce insoluble calcium tartrate. This precipitate is th |  |
| Tartaric Acid | TARTARIC ACID, L, ACS Reagent, powder, (Synonym: 2,3-Dihydroxybutanedioic Acid), Formula: HO2CCH(OH)CH(OH)CO2H. CAS No. 87-69-4. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! |  Texas TX |
| Tartaric Acid 87-69-4 | Tartaric Acid - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Tartaric acid aq. solution | Tartaric acid aq. solution. Group: Acids and alkalis. CAS No. 87-69-4. |  |
| Tartaric Acid BP/USP | Tartaric Acid BP/USP. CAS No. 87-69-4. Molecular formula: C4H6O6. |  |
| Tartaric Acid, Granular, NF | L-(+)-Tartaric Acid; 2,3-Dihydroxybutanedioic Acid. cationic transfection agent, bile acid sequestrant, vaccine adjuvant, protein stabilizer. Grades: NF. CAS No. 87-69-4. Product ID: 8-01600. Molecular formula: C4H6O6. Mole weight: 150.09 . Reference: Other molecular weights available. Please inquire. |  |
| Tartaric Acid Impurity 2 | Tartaric Acid Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133-37-9. Molecular formula: C4H6O6. Mole weight: 150.09. Catalog: APB133379. | |
| Tartaric Acid Methyl Ester | Tartaric Acid Methyl Ester is useful for developing stabilizers as additives in methanol-gasoline. In addition, Tartaric Acid Methyl Ester can be used to synthesize novel enantiopure γ/δ-amino acid via trans-acetalization. Group: Biochemicals. Grades: Highly Purified. CAS No. 3333-46-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C5H8O6. US Biological Life Sciences. | Worldwide |
| Tartary Buckwheat Extract | Tartary Buckwheat Extract. Applications: Used for health care products, dietary supplements, reduce blood press, antioxidant. Group: Others. Synonyms: Tartary Buckwheat Extract; Fagopyrum tataricum (L.) Gaertn. Purity: 30%-70% Total Flavonoid By UV. Appearance: Yellow green fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Fagopyrum tataricum (L.) Gaertn. Tartary Buckwheat Extract; Fagopyrum tataricum (L.) Gaertn; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-099. | |
| Tart Cherry Fruit Powder & 4:1 | Tart Cherry Fruit Powder & 4:1. |  CA, FL & NJ |
| tartrate decarboxylase | This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: (R,R)-tartrate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.73. CAS No. 124248-30-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4821; tartrate decarboxylase; EC 4.1.1.73; 124248-30-2; (R,R)-tartrate carboxy-lyase. Cat No: EXWM-4821. | |
| tartrate dehydrogenase | meso-tartrate and (R,R)-tartrate act as substrates. Requires Mn2+ and a monovalent cation. Group: Enzymes. Synonyms: mesotartrate dehydrogenase. Enzyme Commission Number: EC 1.1.1.93. CAS No. 37250-29-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0377; tartrate dehydrogenase; EC 1.1.1.93; 37250-29-6; mesotartrate dehydrogenase. Cat No: EXWM-0377. | |
| tartrate epimerase | This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on hydroxy acids and derivatives. This enzyme participates in glyoxylate and dicarboxylate metabolism. Group: Enzymes. Synonyms: tartaric racemase. Enzyme Commission Number: EC 5.1.2.5. CAS No. 37318-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5392; tartrate epimerase; EC 5.1.2.5; 37318-33-5; tartaric racemase. Cat No: EXWM-5392. | |
| Tartrate Standard for IC | certified reference material. Group: Anions and cations standards. | |
| Tartrazine | Tartrazine. CAS No. 1934-21-0. Product ID: PE-0212. Molecular formula: C16H13N4NaO9S2. Mole weight: 492.41. Category: Colorant Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Semi-solid Dosage Form; Suppository Bases; Colorant Excipients; Tartrazine; PE-0212; C16H13N4NaO9S2; 1934-21-0; 1934-21-0. Appearance: Orange Powder. Purity: 0.99. Synonym(s): 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-1H-Pyrazole-3-carboxylic acid, trisodium salt. Solubility: DMSO (Sparingly, Heated), Water (Slightly). Storage: room temp. Boiling Point: 909.54°C[at 101 325 Pa]. Melting Point: 300 °C. Density: 2.121[at 20°C]. | |
| Tartrazine | Tartrazine, a kind of azo dye, could also be used in pharmaceuticals and has been found to cause allergic and intolerance reactions in patients with asthmatics. Synonyms: Acid Yellow 23; 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-[2-(4-sulfophenyl)diazenyl]-1H-pyrazole-3-carboxylic Acid Sodium Salt; Aizen Tartrazine; Vondacid Tartrazine; Wool Yellow. Grades: >95%. CAS No. 1934-21-0. Molecular formula: C16H9N4Na3O9S2. Mole weight: 534.37. | |
| Tartrazine | Tartrazine. Group: Biochemicals. Alternative Names: 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-[2-(4-sulfophenyl)diazenyl]-1H-pyrazole-3-carboxylic acid sodium salt; Aizen tartrazine; Acid yellow 23. Grades: Highly Purified. CAS No. 1934-21-0. Pack Sizes: 100g, 250g, 500g, 1Kg, 2Kg. Molecular Formula: C16H9N4Na3O9S2. US Biological Life Sciences. | Worldwide |
| Tartrazine | Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Yellow 23; FD&C Yellow No. 5. CAS No. 1934-21-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0257. | |
| Tartrazine ≥85% (Dye content) | Tartrazine ≥85% (Dye content). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 500g. US Biological Life Sciences. | Worldwide |
| tartronate O-hydroxycinnamoyltransferase | 4-Coumaroyl-CoA (4-hydroxycinnamoyl-CoA), caffeoyl-CoA (3,4-dihydroxycinnamoyl-CoA) and feruloyl-CoA (4-hydroxy-3-methoxycinnamoyl-CoA) can also act as donors for the enzyme from the mung bean (Vigna radiata). Group: Enzymes. Synonyms: tartronate sinapoyltransferase; hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase. Enzyme Commission Number: EC 2.3.1.106. CAS No. 102484-57-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2044; tartronate O-hydroxycinnamoyltransferase; EC 2.3.1.106; 102484-57-1; tartronate sinapoyltransferase; hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase. Cat No: EXWM-2044. | |
| tartronate-semialdehyde synthase | A flavoprotein. Group: Enzymes. Synonyms: tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming). Enzyme Commission Number: EC 4.1.1.47. CAS No. 9027-24-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4792; tartronate-semialdehyde synthase; EC 4.1.1.47; 9027-24-1; tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming). Cat No: EXWM-4792. | |
| Tartronic Acid (Hydroxymalonic Acid) | Tartronic Acid (Hydroxymalonic Acid). Group: Biochemicals. Alternative Names: Hydroxymalonic acid; Propanedioic acid, hydroxy-; Malonic acid, hydroxy-; 2-Hydroxypropanedioic acid;2-Hydroxypropanedioic acid; EINECS 201-301-1; MALONIC ACID, HYDROXY-; NSC 36171; Tartronic acid; UNII-34T0025E0L; Propanedioic acid, hydroxy-; Propanedioic acid, hydroxy- (9CI); Tartronic acid. Grades: Highly Purified. CAS No. 80-69-3. Pack Sizes: 100mg. Molecular Formula: C?H?O?, Molecular Weight: 120.06. US Biological Life Sciences. | Worldwide |
| TAS0728 | TAS0728 is a potent and seletive HER2 inhibitor possibly used for the treatment of various cancers. It covalently binds to HER2 at C805 and selectively inhibits its kinase activity. Synonyms: (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-N-(4-(2-(dimethylamino)-2-oxoethyl)-2,3-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3-carboxamide. CAS No. 2088323-16-2. Molecular formula: C26H32N8O3. Mole weight: 504.6. | |
| TAS-102 | TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Synonyms: Tipiracil / Trifluridine; Viroptic mixture with 5-CIMU; TAS 102; EX-A1755; Tipiracil hydrochloride / Trifluridine. CAS No. 733030-01-8. Molecular formula: C9H11ClN4O2·HCl·C10H11F3N2O5. Mole weight: 575.328. | |
| TAS-103 | TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103. TAS-103 may be useful in the chemotherapy of colorectal cancer. Uses: Topoisomerase i inhibitors. Synonyms: BMS-247615; TAS103; TAS 103; BMS247615; BMS 247615. Grades:>98%. CAS No. 174634-08-3. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| TAS-103 dihydrochloride | TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103. Synonyms: 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride; TAS103; TAS-103; TAS 103; BMS247615; BMS 247615; BMS-247615. Grades:>98%. CAS No. 174634-09-4. Molecular formula: C20H21Cl2N3O2. Mole weight: 406.31. | |
| TAS-108 | TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland and uterus and upregulated in estrogen-dependent tumors. Blockage of ERa by TAS-108 prevents the binding and effects of estrogen and may lead to an inhibition of estrogen-dependent cancer cell proliferation. TAS-108 also is a partial agonist of the estrogenic receptor beta (ERb), expressed in many tissues including the central nervous system, urogenital tract, bone and cardiovascular system, thereby exerting a positive effect on these tissues. In addition, TAS-108 activates the co-repressor Silencing Mediator for Retinoid and Thyroid hormone receptor (SMRT), a protein that inhibits the activities of the estrogen receptors, which may contribute to the antitumor activity of TAS-108. Synonyms: TAS108; TAS 108; SR16234; SR 16234; SR-16234; (7alpha)-21-(4-((Diethylamino)methyl)-2-methoxyphenoxy)-7-methyl-19-norpregna-1,3,5(10)-trien-3-ol 2-hydroxy-1,2,3-propanetricarboxylate. Grades: >98%. CAS No. 229634-98-4. Molecular formula: C39H55NO10. Mole weight: 697.86. | |
| TAS-114 | TAS-114 is an orally active dual dUTPase/dihydropyrimidine dehydrogenase (DPD) inhibitor, can improving the therapeutic efficacy of fluoropyrimidine[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198221-21-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124062. | |
| TAS-115 | This active molecular is a c-MET and VEGFR inhibitor which is selective and specific in vitro. In vivo studies, TAS-115 suppressed the progression of MET-inactivated tumor completely through blocking angiogenesis without toxicity and it also induced marked tumor shrinkage and prolonged survival in animal model. In Dec 2013, Phase-I development was ongoing in Japan. In Dec 2014, Taiho Pharmaceutical completed a phase I trial for Solid tumours in Japan. In Apr 2016, preclinical data was presented. Uses: Solid tumours. Synonyms: TAS-115; TAS 115; TAS115; 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide. Grades: 98%. CAS No. 1190836-34-0. Molecular formula: C27H23FN4O4S. Mole weight: 518.56. | |
| TAS-116 | TAS-116 is a inhibitor of Hsp90. It induces significant cytotoxicity in MM cells even in the presence of BMSCs, associates with downregulation of phospho-Akt and phospho-ERK. In addition, neither exogenous IL-6 nor IGF-1 was able to protect against TAS-116. Importantly, TAS-116 did not induce cytotoxicity in BMSCs. TAS-116 enhanced bortezomib-induced cytotoxicity in MM.1S and RPMI-8226 cells, associated with decreased phospho-Akt, phospho-RelA (p65), phospho-IkBa, and phospho-IKKα/β; as well as increased CHOP and PARP cleavage. These results suggest that TAS-116 blocks bortezomib-induced canonical NF-κB pathway and augments bortezomib-induced endoplasmic reticulum (ER) stress. Synonyms: TAS116; TAS 116; TAS-116; 3-Ethyl-4-[3-(1-methylethyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-1H-pyrazolo[3,4-b]pyridin-1-yl]benzamide. Grades: >98%. CAS No. 1260533-36-5. Molecular formula: C25H26N8O. Mole weight: 454.54. | |
| TAS-119 | TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC 50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B ( IC 50 of 95 nM). TAS-119 has potent antitumor activites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453099-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137377. | |
| TAS 301 | TAS 301. Group: Biochemicals. Grades: Purified. CAS No. 193620-69-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAS-301 | TAS-301 is a potent and selective constrictive remodeling regulator on renarrowing after balloon overstretch injury of porcine coronary artery. TAS-103 inhibits smooth muscle cell migration and proliferation. Synonyms: TAS-301; TAS301; TAS301. Grades: 98%. CAS No. 193620-69-8. Molecular formula: C23H19NO3. Mole weight: 357.41. | |
| TAS-301 | ?95% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| TAS4464 | TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-128586. | |
| TAS4464 | TAS4464 is a potent and selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. It selectively inhibits NAE relative to the other E1s UAE and SAE. TAS4464 treatment inhibits cullin neddylation and subsequently induces the accumulation of CRL substrates such as CDT1, p27, and phosphorylated IkBa in human cancer cell lines. Synonyms: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-[(aminosulfonyl)amino]-5-deoxy-beta-D-ribofuranosyl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]-. CAS No. 1848959-10-3. Molecular formula: C21H23FN6O6S. Mole weight: 506.5. | |
| TAS4464 hydrochloride | TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. TAS4464 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128586A. | |
| TAS6417 | TAS6417 is a novel EGFR inhibitor that targets EGFR exon 20 insertion mutations while sparing wild-type (WT) EGFR. TAS6417 inhibited EGFR phosphorylation and downstream molecules in NSCLC cell lines expressing EGFR exon 20 insertions, resulting in caspase activation. Synonyms: CLN-081; TPC-064; TAS 6417; TAS-6417; Zipalertinib. CAS No. 1661854-97-2. Molecular formula: C23H20N6O. Mole weight: 396.44. | |
| TaSe2 Crystal | TaSe2 Crystal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tantalumdiselenide;tantalumselenide(tase2);TANTALUM SELENIDE;Tantalum(IV) selenide. Product Category: Graphene-like Materials Series. CAS No. 12039-55-3. Molecular formula: Se2Ta. Mole weight: 338.87. Purity: 0.99995. Product ID: ACM12039553. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tantalum selenide (TaSe2). | |
| Taselisib | Taselisib, also known as GDC0032 or RG7606, is a selective, potent, orally bioavailable inhibitor of PI3Ka with a Ki = 0.2nM, and with reduced inhibitory activity against PI3K. This selectivity profile, and excellent pharmacokinetic and pharmaceutical properties, allowed for greater efficacy in vivo at the maximum tolerated dose relative to a pan Class I PI3K inhibitor in PIK3CA mutant xenografts. Notably, GDC-0032 preferentially inhibited PIK3CA mutant cells relative to cells with wild-type PI3K. GDC-0032 potently inhibits signal transduction downstream of PI3K and induces apoptosis at low concentrations in breast cancer cell lines and xenograft models that harbor PIK3CA mutations. Synonyms: GDC-0032; GDC0032; GDC 0032; RG7604; RG-7604; RG 7604; Taselisib. CAS No. 1282512-48-4. Molecular formula: C24H28N8O2. Mole weight: 460.542. | |
| Taselisib | Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with K i s of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0032; RG-7604. CAS No. 1282512-48-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13898. | |
| Tasidotin | Tasidotin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tasidotin [INN], UNII-05G07285DK, CID9895066, CID 9895066, 192658-64-3. Product Category: Heterocyclic Organic Compound. CAS No. 192658-64-3. Molecular formula: C32H59ClN6O5. Mole weight: 643.3. Purity: 0.96. IUPACName: (2S)-N-tert-butyl-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide. Product ID: ACM192658643. Alfa Chemistry ISO 9001:2015 Certified. | |
| Tasidotin hydrochloride | Tasidotin, also know as ILX-651, is an orally active synthetic microtubule-targeted derivative of the marine depsipeptide dolastatin-15, is currently undergoing clinical evaluation for cancer treatment. Tasidotin inhibited proliferation of MCF7/GFP breast cancer cells with an IC(50) of 63 nmol/L and inhibited mitosis with an IC(50) of 72 nmol/L in the absence of detectable effects on spindle microtubule polymer mass. Tasidotin inhibited the polymerization of purified tubulin into microtubules weakly (IC(50) approximately 30 micromol/L). However, it strongly suppressed the dynamic instability behavior of the microtubules at their plus ends at concentrations approximately 5 to 10 times below those required to inhibit polymerization. Synonyms: ILX 651; ILX651; ILX-651. CAS No. 623174-20-9. Molecular formula: C32H59ClN6O5. Mole weight: 643.31. | |
| Tasimelteon | Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep-wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved. Uses: Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. it helps to correct the circadian rhythm disorder often seen in patients who are visually impaired. Synonyms: BMS-214,778; BMS-214778; BMS214778; BMS 214778. VEC-162; VEC162; VEC 162. Trade name: Hetlioz. Grades: ≥ 99.0%. CAS No. 609799-22-6. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Tasimelteon | Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-214778; VEC-162. CAS No. 609799-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14803. | |
| Tasimelteon | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TASIN-1 | TASIN-1 is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 792927-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116572A. | |
| TASIN-1 | TASIN-1 is an inhibitor of adenomatous polyposis coli (APC) that kills colorectal cancer cells that express APC by reducing cellular cholesterol levels. It also inhibits AKT activity through a cholesterol-dependent manner. Synonyms: 1'-[(4-Methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine. Grades: ≥98%. CAS No. 792927-06-1. Molecular formula: C18H28N2O3S. Mole weight: 352.5. | |
| TASIN-1 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TASIN-30 | TASIN-30 is an EBP inhibitor, with EC50 values of 0.097 ?M for EBP competition and 50 ?M for DHCR7 competition, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1678515-93-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164561. | |
| Tasipimidine sulfate | Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a p EC 50 of 7.57 against human α2A-adrenoceptor. Tasipimidine sulfate can be used for situational anxiety and fear research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1465908-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109075A. | |
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