A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Mifomelatide. CAS No. 1456699-27-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5971.
TC-MCH 7c
TC-MCH 7c is a potent, selective and brain-penetrating antagonist of melanin-concentrating hormone receptor 1 (MCH1R) (IC50= 5.6 nM in hMCH1R-expressing CHO cells), displaying selectivity for MCH1R over MCH2R (IC50 = > 10 μM). Study shows that TC-MCH 7c reduces body weight in a mouse model of diet-induced obesity. Synonyms: TC-MCH 7c; TC MCH 7c; TCMCH 7c; 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone. Grades: ≥97% by HPLC. CAS No. 864756-35-4. Molecular formula: C24H25FN2O3. Mole weight: 408.47.
TC-MCH 7c
TC-MCH 7c. Group: Biochemicals. Grades: Purified. CAS No. 864756-35-4. Pack Sizes: 10mg. US Biological Life Sciences.
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TCMDC-135051
TCMDC-135051 is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413716-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126323.
TCMDC-135051 hydrochloride
TCMDC-135051 hydrochloride is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2705545-47-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126323B.
TC Mps1 12
TC Mps1 12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor (IC50 = 6.4 nM) with selectivity for Mps1 over a panel of 95 kinases including JNK. TC Mps1 12 has been shown to inhibit the proliferation of A549 lung carcinoma cell and the growth of A549 cell xenograft in mice. Synonyms: TC-Mps1-12; TC Mps1 12; TCMps112; TC-Mps1 12; 4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide. Grades: ≥99% by HPLC. CAS No. 1206170-62-8. Molecular formula: C17H20N6O. Mole weight: 324.38.
TC Mps1 12
TC Mps1 12. Group: Biochemicals. Grades: Purified. CAS No. 1206170-62-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCMTB
TCMTB is one of the so-called emerging contaminants (EC). TCMTB is also an antifouling agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21564-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101425.
TC-N 1752
TC-N 1752. Group: Biochemicals. Grades: Purified. CAS No. 1211866-85-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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TC-N 1752
TC-N 1752 is a potent and orally active inhibitor of Nav1.7, with IC50s of 0.17 ?M, 0.3 ?M, 0.4 ?M, 1.1 ?M and 2.2 ?M at hNav1.7, hNav1.3, hNav1.4, hNaV1.5 and rNav1.8, respectively. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. TC-N 1752 shows analgesic efficacy in the Formalin model of pain[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1211866-85-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107405.
TC-N 1752
TC-N 1752 is a state-dependent human NaV channel inhibitor (IC50 = 0.17, 0.3, 0.4, 1.1 and 1.6 μM at hNaV1.7, hNaV1.3, hNaV1.4, hNaV1.5 and hNav1.9, respectively). TC-N 1752 inhibits Nav1.7 and exhibits analgesic efficacy in the formalin pain model. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. Synonyms: N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide; Nav1.7 blocker 52. Grades: ≥99% by HPLC. CAS No. 1211866-85-1. Molecular formula: C25H27F3N6O3. Mole weight: 516.52.
TCN 201
TCN 201. Group: Biochemicals. Grades: Purified. CAS No. 852918-02-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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TCN 201
TCN 201 is an NMDA receptor antagonist with selectivity for NR1/NR2A over NR1/NR2B-containing receptors (pIC50 = 6.8 and <4.3, respectively, in human recombinant NR1/NR2A and NR1/NR2B FLIPR/Ca2+ assays). Synonyms: TCN-201, TCN 201, TCN201; 3-Chloro-4-fluoro-N- [4- [ [2- (phenylcarbonyl) hydrazino] carbonyl] benzyl] benzenesulfonamide; QCR-22. Grades: ≥99% by HPLC. CAS No. 852918-02-6. Molecular formula: C21H17ClFN3O4S. Mole weight: 461.89.
A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Group: Biochemicals. Grades: Highly Purified. CAS No. 852918-02-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
TCN 213
TCN 213 is an NMDA receptor antagonist with selectivity for NR1/NR2A (pIC50 = 5.4) over NR1/NR2B. Synonyms: TCN 213; TCN213; TCN-213; N-(Cyclohexylmethyl)-2-[(5-[(phenylmethyl)amino]-1,3,4-thiadiazol-2-yl}thio]acetamide. Grades: ≥99% by HPLC. CAS No. 556803-08-8. Molecular formula: C18H24N4OS2. Mole weight: 376.54.
TCN 213
TCN 213. Group: Biochemicals. Alternative Names: N-(Cyclohexylmethyl)-2-[[5-[(phenylmethyl)amino]-1,3,4-thiadiazol-2-yl]thio]-acetamide. Grades: Highly Purified. CAS No. 556803-08-8. Pack Sizes: 10mg. Molecular Formula: C18H24N4OS2, Molecular Weight: 376.54. US Biological Life Sciences.
Worldwide
TC-N 22A
TC-N 22A. Group: Biochemicals. Grades: Purified. CAS No. 1314140-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TC-N 22A
TC-N 22A is a potent and selective mGlu4 receptor positive allosteric modulator (EC50 = 9 nM in human mGlu4-expressing BHK cells) with selectivity over mGlu1, mGlu2, mGlu3, mGlu5 and mGlu7 receptors (EC50 > 10 μM). TC-N 22A is used for the treatment of Parkinson's disease, anxiety and pain. Uses: The treatment of parkinson's disease, anxiety and pain. Synonyms: 4, 5, 6, 8-Tetrahydro-N-2-pyridinylpyrazolo[3', 4':6, 7]cyclohepta[1, 2]thiazol-2-amine; N-pyridin-2-yl-4, 5, 6, 7-tetrahydropyrazolo[2, 3]cyclohepta[2, 4-b][1, 3]thiazol-2-amine. Grades: ≥98% by HPLC. CAS No. 1314140-00-5. Molecular formula: C14H13N5S. Mole weight: 283.35.
TCN 237 dihydrochloride
TCN 237 dihydrochloride is a potent and NR2B-selective NMDA antagonist (Ki = 0.8 nM), blocks NR2B-mediated calcium influx in Ltk cells (Ki = 9.7 nM). Uses: Highly potent nr2b-selective nmda receptor antagonist. Synonyms: NMDA-IN-1; TCN 237 dihydrochloride; TCN237 dihydrochloride; TCN-237 dihydrochloride; 2-[[4-[(2-Fluorophenyl)methyl]-1-piperidinyl]methyl]-1H-benzimidazol-6-ol dihydrochloride. Grades: ≥98%. CAS No. 700878-19-9. Molecular formula: C20H24Cl2FN3O. Mole weight: 412.33.
TCN 237 dihydrochloride
TCN 237 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 700878-19-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TCN238
TCN238 is an orally available, brain penetrant and positive allosteric mGlu4 receptor modulator (EC50 = 1 μM) with 30-fold selectivity over mGluR5 using human recombinant receptors in CHO-K1 cells. Synonyms: Lu AF32615; Lu AF-32615; Lu AF 32615; Lu-AF32615; LuAF32615; TCN-238; TCN 238; TCN238; 4-[(E)-2-phenylethenyl]pyrimidin-2-amine. CAS No. 125404-04-8. Molecular formula: C12H11N3. Mole weight: 197.24.
TCN 238
TCN 238. Group: Biochemicals. Grades: Purified. CAS No. 125404-04-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
tCnitro-CE Phosphoramidite
tCnitro-CE Phosphoramidite, a reagent vital for the synthesis of oligonucleotides, features a promising nitro group situated at the 5'-end capable of introducing a modification or label. Its applications in nucleic acid-based technologies like gene editing and diagnostics research remain unparalleled. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(7-nitro-1,3-diaza-2-oxophenothiazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H49N6O9PS. Mole weight: 880.94.
tCnitroNucleoside
tCnitroNucleoside is a multifaceted biomedical compound used to study cancer, viral infections and genetically rooted ailments. Grades: ≥ 95%. CAS No. 1139889-25-0. Molecular formula: C15H14N4O6S. Mole weight: 378.36.
TC NTR1 17
TC NTR1 17 is a non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50 < 15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). TC NTR1 17 displays over 50-fold selectivity for NTS1 over NTS2 and GPR35. Synonyms: N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine; (2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-4-methylpentanoic acid. Grades: ≥99% by HPLC. CAS No. 1146757-96-1. Molecular formula: C27H27ClN4O5. Mole weight: 522.98.
TC NTR1 17
TC NTR1 17. Group: Biochemicals. Grades: Purified. CAS No. 1146757-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCNT Type 1- Carbon Nanotubes Thin Walled
TCNT Type 1- Carbon Nanotubes Thin Walled. Group: Nanotubes. CAS No. 308068-56-6.
tC Nucleoside
tC Nucleoside, an exceptional fluorescent analogue of thymidine intended for DNA synthesis and detection, has proven to be instrumental in numerous DNA studies. Its use in DNA hybridization, polymerase chain reaction (PCR), and DNA sequencing is scientifically deemed significant. Additionally, its exclusive fluorescent properties have contributed significantly to drug discovery research as it enables accurate detection of interactions with DNA. Grades: ≥ 97%. CAS No. 162902-04-7. Molecular formula: C15H15N3O4S. Mole weight: 333.36.
TC-O9311
TC-O9311 is a potent, selective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139) with no activity against a range of 90 diverse targets. Synonyms: 3,5-dimethoxy-benzoic acid, 2-[ (1-naphthalenylamino) carbonyl]hydrazide; TC-O 9311; TC-O-9311; TC-O9311; TCO 9311; TCO-9311; TCO9311. CAS No. 444932-31-4. Molecular formula: C20H19N3O4. Mole weight: 365.38.
TC-O 9311
TC-O 9311. Group: Biochemicals. Grades: Purified. CAS No. 444932-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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TCO-NHS ester
TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191901-33-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141165.
TCO-PEG3-Biotin
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136050.
TCO-PEG3-FITC
A FITC probe functionalized with a TCO moiety for tetrazine-TCO ligation and a PEG3 spacer. Uses: For industrial and laboratory use. Product Category: Other Fluorescent Dyes. Appearance: Orange solid. Molecular formula: C38H43N3O10S. Mole weight: 733.83 g/mol. Purity: 0.95. Product ID: DYE-FLU-0102. Alfa Chemistry ISO 9001:2015 Certified.
TCO-PEG3-maleimide
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809356-72-6. Pack Sizes: 5 mg. Product ID: HY-151696.
TCO-PEG4-NHS ester
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621096-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141167A.
TCO-PEG4-VC-PAB-MMAE
TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758671-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148057.
TC OT 39
TC OT 39 is a potent non-peptide oxytocin receptor partial agonist (EC50 = 33 nM and 850 nM for the oxytocin receptor and V2 vasopressin receptor, respectively). TC OT 39 is also a V1a vasopressin receptor antagonist (Ki = 330 nM). Synonyms: TC-OT 39, TC OT 39, TCOT 39; (2S)-N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-2-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thioxomethyl]-1-pyrrolidinecarboxamide. Grades: ≥97% by HPLC. CAS No. 479232-57-0. Molecular formula: C32H40N8O2S. Mole weight: 600.78.
TC OT 39
TC OT 39. Group: Biochemicals. Grades: Purified. CAS No. 479232-57-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TC-P 262
TC-P 262. Group: Biochemicals. Grades: Purified. CAS No. 873398-67-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TC-P 262
TC-P 262 is a selective P2X3 and P2X2/3 receptor antagonist (pIC50 = 7.39 and 6.68, respectively). TC-P 262 has no detectable activity at P2X1, P2X2, P2X4 and P2X7 receptors (pIC50 < 4.7). Synonyms: 5-[5-Methyl-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine. Grades: ≥99% by HPLC. CAS No. 873398-67-5. Molecular formula: C14H18N4O. Mole weight: 258.32.
Tcpobop
TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 76150-91-9. Molecular formula: C16H8Cl4N2O2. Mole weight: 402.06. Purity: 0.9807. Product ID: ACM76150919. Alfa Chemistry ISO 9001:2015 Certified.
TCPOBOP
TCPOBOP. Group: Biochemicals. Grades: Purified. CAS No. 76150-91-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCPOBOP
TCPOBOP is an constitutive androstane receptor (mCAR) agonist with EC50 value of 20 nM. But it is effective for the mouse receptor but not for human or rat CAR receptors. TCPOBOP can induce cytochrome P450 monooxygenases and multidrug resistance and xenobiotic efflux proteins. Synonyms: 1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene;2,2'-(1,4-Phenylenebis(oxy))bis(3,5-dichloropyridine). Grades: 98%. CAS No. 76150-91-9. Molecular formula: C16H8Cl4N2O2. Mole weight: 402.06.
TCPP-Mn(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: Endo-Mn-meso-tetra(4-carboxyphenyl)porphine; hydron,manganese(2+),4-[10,15,20-tris(4-carboxylatophenyl)porphyrin-22,24-diid-5-yl]benzoate. CAS No. 73202-95-6. Molecular formula: 840.67. Mole weight: C48H24N4O8Mn-4·H+. 95%.
TCPP-Ni(2+)
TCPP-Ni(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: meso-Tetra(4-carboxyphenyl)porphine-Ni(II); 5,10,15,20-Tetrakis(4-Carboxyphenyl)porphyrin-Ni(II). CAS No. 41699-92-7. Molecular formula: 847.45. Mole weight: C48H28N4NiO8. 95%.
TCPP-Pd(2+)
TCPP-Pd(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: Pd(II) meso-Tetra(4-carboxyphenyl)porphine. CAS No. 94288-44-5. Molecular formula: 895.20. Mole weight: C48H28N4O8Pd. 95%.
TCPP [=Tetrakis(4-carboxyphenyl)porphyrin] [Ultra-high sensitive spectrophotometric reagent for Cu, Cd] [For the simultaneous determination of metals by HPLC]
TCPP-Zn(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: Zinc(II) tetrakis(4-carboxyphenyl)porphine; Zn(II) Meso-tetra(4-carboxyphenyl) porphine. CAS No. 27647-84-3. Molecular formula: 850.12. Mole weight: C48H24N4O8-6·Zn+2. 95%.
TC-PTP Active human
recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
TCPZ
TCPZ. Uses: Host material containing a triazine core and three phenylcarbazole arms for phosphorescent organic light-emitting diodes. Group: Organic light-emitting diode (oled) materials. Alternative Names: 2,4,6-Tris(3-(carbazol-9-yl)phenyl)triazine. CAS No. 890148-68-2. Product ID: 9-[3-[4,6-bis(3-carbazol-9-ylphenyl)-1,3,5-triazin-2-yl]phenyl]carbazole. Molecular formula: 804.94. Mole weight: C57H36N6. C1=CC=C2C (=C1) C3=CC=CC=C3N2C4=CC=CC (=C4) C5=NC (=NC (=N5) C6=CC (=CC=C6) N7C8=CC=CC=C8C9=CC=CC=C97) C1=CC (=CC=C1) N1C2=CC=CC=C2C2=CC=CC=C21. InChI=1S/C57H36N6/c1-7-28-49-43 (22-1)44-23-2-8-29-50 (44)61 (49)40-19-13-16-37 (34-40)55-58-56 (38-17-14-20-41 (35-38)62-51-30-9-3-24-45 (51)46-25-4-10-31-52 (46)62)60-57 (59-55)39-18-15-21-42 (36-39)63-53-32-11-5-26-47 (53)48-27-6-12-33-54 (48)63/h1-36H. KOUVXIWGXJSZHF-UHFFFAOYSA-N.
T.cruzi Inhibitor
T.cruzi Inhibitor is a novel inhibitor of Trypanosoma cruzi. Synonyms: N-Benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide. CAS No. 1350920-22-7. Molecular formula: C22H25F3N2O. Mole weight: 390.45.
TCS 1102
TCS 1102 is a potent, dual orexin receptor antagonist with Ki values of 0.2 and 3 nM for OX2 and OX1 receptors respectively. It is a poor substrate for P-glycoprotein, which demonstrates good brain penetration when administered intraperitoneally. It were found to decrease fear and anxiety in rats 14 days after exposure to footshock. It was also found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze. Uses: Tcs 1102 was found to have anxiolytic effects. Synonyms: N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl-2-pyrrolidinedicarboxamide;2-PyrrolidinecarboxaMide, N-[1,1'-biphenyl]-2-yl-1-[2-[(1-Methyl-1H-benziMidazol-2-yl)thio]acetyl]-, (2S)-;(2S)-N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-2-pyrrolidinecarboxamide;TCS 1102, TCS1102, TCS-1102;(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide. Grades: >98 %. CAS No. 916141-36-1. Molecular formula: C27H26N4O2S. Mole weight: 470.59.
TCS 1102
TCS 1102 is a potent, dual orexin receptor antagonist, with Ki values of 0.2 nM and 3 nM for OX2 and OX1 receptors, respectively. TCS 1102 demonstrates excellent blood-brain barrier penetrability and moderate bioavailability in rats[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 916141-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10900.