American Chemical Suppliers

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Product
t-Butyl-N-carbobenzyloxy-L-aspartyl-L-proline t-Butyl-N-carbobenzyloxy-L-aspartyl-L-proline. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
t-Butylnorsynephrine t-Butylnorsynephrine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Salbutamol Sulphate Imp. B (EP), Salbutamol Imp. B (EP), (1RS)-2-[(1,1-Dimethylethyl)amino]-1-(4-hydroxyphenyl)ethanol. CAS No. 96948-64-0. Pack Sizes: 10MG. IUPAC Name: 4-[2-(tert-butylamino)-1-hydroxyethyl]phenol. Molecular Formula: C12H19NO2. Mole Weight: 209.28. Catalog: APS96948640A. SMILES: CC(C)(C)NCC(O)c1ccc(O)cc1. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products
t-Butylsulfinamide Butylsulfinamide. CAS No. 146374-27-8. Categories: 2-methylpropane-2-sulfinamide. Richman Chemical
Pennsylvania PA
t-Butyltrichlorogermane Organic Germanium. Alternative Names: T-BUTYLTRICHLOROGERMANE;TERT-BUTYLTRICHLOROGERMANE. CAS No. 1184-92-5. Molecular formula: C4H9Cl3Ge. Mole weight: 236.11. Catalog: ACM1184925. Alfa Chemistry. 2
tBuXPhos Pd G1 Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides. Catalyst for rapid C-N bond-forming process at low catalyst loading. Catalyst for C-N cross-coupling reactions, at or below room temperature. Efficient Pd-catalyzed amination reactions for heterocycle functionization. Group: Palladium series catalysts. Alternative Names: Chloropalladium(1+);ditert-butyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;2-phenylethanamine. CAS No. 1142811-12-8. Molecular formula: C37H55ClNPPd. Mole weight: 686.7. Appearance: Powder. Purity: 0.98. IUPACName: chloropalladium(1+);ditert-butyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;2-phenylethanamine. Canonical SMILES: CC (C)C1=CC (=C (C (=C1)C (C)C)C2=CC=CC=C2P (C (C) (C)C)C (C) (C)C)C (C)C. C1=CC=C ([C-]=C1)CCN. Cl[Pd+]. Catalog: ACM1142811128-1. Alfa Chemistry. 2
tBuXPhos Pd G3 Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media. Alternative Names: TBuXPhos-Pd-G3. CAS No. 1447963-75-8. Molecular formula: C42H59NO3PPdS. Mole weight: 795.4. Appearance: Yellow solid. Purity: 0.98. Catalog: ACM1447963758. Alfa Chemistry. 2
TC 1 TC 1 is a high affinity σ1 receptor ligand with selectivity over σ2 receptors (Ki = 10 and 370 nM respectively). TC 1 exhibits low affinity for dopamine (DAT), serotonin (SERT), noradrenalin (NET) transporters (Ki > 10 μM) and dopamine D2 receptors (Ki = 1226 nM). Synonyms: TC 1; TC1; TC-1; (N-(3'-Fluorophenyl)ethyl-4-azahexacyclo[5.4.1.02, 6.03, 10.05, 9.08, 11]dodecan-3-ol. Grades: ≥99% by HPLC. CAS No. 362512-81-0. Molecular formula: C19H20FNO. Mole weight: 297.37. BOC Sciences 10
TC 1 TC 1. Group: Biochemicals. Grades: Purified. CAS No. 362512-81-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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TC11 TC11 is a MCL1 degrader and Caspase-9 and CDK1 activator. TC11 functions as a phenylacetylamide derivative and is structurally related to immunomodulatory active molecules. TC11 induces degradation of MCL1 leading to apoptotic death [1] [2] during prolonged mitotic arrest. Uses: Scientific research. Group: Signaling pathways. CAS No. 100823-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129478. MedChemExpress MCE
TC 14012 TC 14012. Group: Biochemicals. Grades: Purified. CAS No. 368874-34-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
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TC 14012 TC 14012 is an antagonist of CXCR4. Synonyms: TC 14012; TC14012; TC-14012; L- arginyl- L- arginyl- 3- (2- naphthalenyl)- L- alanyl- L- cysteinyl- L- tyrosyl- N5- (aminocarbonyl)- L- ornithyl- L- lysyl- N5- (aminocarbonyl)- D- ornithyl- L- prolyl- L- tyrosyl- L- arginyl- N5- (aminocarbonyl)- L- ornithyl- L- cysteinyl- cyclic (4?1. Grades: >95%. CAS No. 368874-34-4. Molecular formula: C90H140N34O19S2. Mole weight: 2066.43. BOC Sciences 3
TC 1698 dihydrochloride TC 1698 dihydrochloride is a selective nicotinic α7 receptor agonist (EC50 = 440 nM) displaying neuroprotective activity. TC 1698 dihydrochloride also displays weak partial agonist/antagonist activity at β-subunit-containing receptors. Synonyms: TC 1698 dihydrochloride; TC1698 dihydrochloride; TC-1698 dihydrochloride; 2-(3-Pyridinyl)-1-azabicyclo[3.2.2]nonane dihydrochloride. Grades: ≥98% by HPLC. CAS No. 787587-06-8. Molecular formula: C13H18N2.2HCl. Mole weight: 275.22. BOC Sciences 10
TC 1698 dihydrochloride TC 1698 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 787587-06-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC 2559 difumarate TC 2559 difumarate. Group: Biochemicals. Grades: Purified. CAS No. 212332-35-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC 2559 difumarate TC 2559 difumarate is a subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 = 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes, respectively). TC 2559 difumarate has the selectivity for (α4)2(β2)3 receptor stoichiometry and can enhance CNS-PNS selectivity ratio. Synonyms: TC 2559 difumarate; TC2559 difumarate; TC-2559 difumarate; 4-(5-ethoxy-3-pyridinyl)-N-methyl-(3E)-3-buten-1-amine difumarate. Grades: ≥98% by HPLC. CAS No. 212332-35-9. Molecular formula: C12H18N2O.2C4H4O4. Mole weight: 438.43. BOC Sciences 10
TC-A 2317 hydrochloride TC-A 2317 hydrochloride is a selective and potent Aurora kinase A (ARK-1) inhibitor (Ki = 1.2 nM and 101 nM for inhibition of Aurora kinase A and Aurora kinase B, respectively) with selectivity over 60 other kinases (IC50 > 1000 nM). TC-A 2317 exhibits great cell permeability and antitumor activity. Synonyms: TC-A2317 HCl; TC-A2317 Hydrochloride; TCA2317 HCl; TC A2317 HCl; TC A2317 Hydrochloride; TCA2317 Hydrochloride; TC-A-2317 hydrochloride; 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride. Grades: ≥98% by HPLC. CAS No. 1245907-03-2. Molecular formula: C19H28N6O.HCl. Mole weight: 392.93. BOC Sciences 10
TC-A 2317 hydrochloride TC-A 2317 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1245907-03-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC AC 28 TC AC 28 is a high affinity BET bromodomain ligand (Kd = 40 and 800 nM for Brd2(2) and Brd2(1), respectively) with 20-fold selectively for the second over the first bromodomain. Synonyms: TC-AC28, TC AC28, TCAC28; 6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid methyl ester. Grades: ≥98% by HPLC. CAS No. 1809296-92-1. Molecular formula: C23H21N5O3. Mole weight: 415.44. BOC Sciences 10
TC AQP1 1 TC AQP1 1 is an aquaporin 1 (AQP1) channel blocker (IC50 = 8 μM). TC AQP1 1 was shown to suppress water flux in Xenopus oocytes. Synonyms: TC-AQP1-1; 3,3'-(1,3-Phenylene)bis(2-propenoic acid); CBMicro_016818; M-phenylenediacrylic acid; M-phenylene diacrylic acid. Grades: ≥98% by HPLC. CAS No. 37710-81-9. Molecular formula: C12H10O4. Mole weight: 218.211. BOC Sciences 10
TC AQP1 1 TC AQP1 1. Group: Biochemicals. Grades: Purified. CAS No. 37710-81-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-AQP1-1 TC-AQP1-1 is an aquaporin 1 (AQP1) channel blocker. Group: Others. Alternative Names: TC-AQP1-1. CAS No. 37710-81-9. Molecular formula: C12H10O4. Mole weight: 218.21. Appearance: Solid powder. Purity: >98%. IUPACName: 3,3'-(1,3-Phenylene)bis(2-propenoic acid). Canonical SMILES: O=C(O)/C=C/C1=CC=CC(/C=C/C(O)=O)=C1. Catalog: ACM37710819. Alfa Chemistry.
TC ASK 10 TC ASK 10. Group: Biochemicals. Grades: Purified. CAS No. 1005775-56-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC ASK 10 TC ASK 10 is a potent and orally bioactive ASK1 inhibitor (IC50 = 14 nM) with selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 > 10 μM). TC ASK 10 blocks downstream JNK1/p38 phosphorylation in cells. Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride; ASK1 Inhibitor 10. Grades: ≥98% by HPLC. CAS No. 1005775-56-3. Molecular formula: C21H21N5O.2HCl. Mole weight: 432.35. BOC Sciences 11
TCB2 TCB2 is an agonist of serotonin 5-HT 2A receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 912342-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103102. MedChemExpress MCE
TCB-2 TCB-2. Group: Biochemicals. Grades: Purified. CAS No. 912342-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TCB-2 TCB-2 is a high affinity 5-HT2A receptor agonist (Ki = 0.73 and 0.75 nM for rat and human receptors, respectively). TCB-2 stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors (EC50 = 36 nM). It also induces head twitches and hypothermia in mice following i.p. adminitration. Synonyms: TCB 2; TCB2; (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide; Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3-bromo-2,5-dimethoxy-, hydrobromide (1:1); Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3-bromo-2,5-dimethoxy-, monohydrobromide; (3-bromo-2,5-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methanamine hydrobromide. Grades: ≥99% by HPLC. CAS No. 912342-28-0. Molecular formula: C11H14BrNO2.HBr. Mole weight: 353.05. BOC Sciences 10
TC-C 14G TC-C 14G. Group: Biochemicals. Grades: Purified. CAS No. 656804-72-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-C 14G TC-C 14G is a potent and high affinity cannabinoid-1 (CB1) receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Synonyms: [2-(2,4-Dichlorophenyl)-6-fluoro-2-(4-fluorophenyl)-1,3-benzodioxol-5-yl]-4-morpholinyl-methanone. Grades: ≥98% by HPLC. CAS No. 656804-72-7. Molecular formula: C24H17Cl2F2NO4. Mole weight: 492.3. BOC Sciences 10
tC°-CE Phosphoramidite tC°-CE Phosphoramidite, a chemical reagent essential in oligonucleotide synthesis for biomedical applications, boasts a thermally cleavable protecting group enabling streamlined purification and deprotection of the end product. Its widespread usage extends to the creation of RNA and DNA probes, utilized regularly in the diagnosis and treatment of maladies such as cancer and viral infections. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(1,3-diaza-2-oxophenoxazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H50N5O8P. Mole weight: 819.88. BOC Sciences 3
tC-CE Phosphoramidite tC-CE Phosphoramidite, a bioorganic compound vital to the biomedicine industry, plays a significant role in synthesizing oligonucleotides used for studying and diagnosing various diseases, ranging from cancer to genetic disorders. Through its unique fluorescent properties, it offers an unparalleled capability to detect and analyze DNA and RNA sequences, unveiling new horizons in the field of bioanalytics. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1'-(1,3-diaza-2-oxophenothiazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C45H50N5O7PS. Mole weight: 835.95. BOC Sciences 3
TC-DAPK 6 An oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 μM. Synonyms: TC-DAPK 6; TC DAPK 6; TCDAPK6; DAPK Inhibitor; T6908224; T-6908224; T 6908224. Grades: >98%. CAS No. 315694-89-4. Molecular formula: C17H12N2O2. Mole weight: 276.29. BOC Sciences 11
TC-DAPK 6 TC-DAPK 6. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC E3 5031 TC E3 5031 is a proteolysis targeting chimeras which allows for the optical control of protein degradation. Synonyms: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid; E3 ligase Ligand 3; Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-; Thalidomide-O-COOH; Thalidomide-Acid; SCHEMBL14085581; Thalidomide-O-COOH (Cereblon ligand 3); 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid. Grades: ≥ 98%. CAS No. 1061605-21-7. Molecular formula: C15H12N2O7. Mole weight: 332.26. BOC Sciences 3
TC-E3 5032 TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders. Synonyms: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione. Grades: ≥ 98%. CAS No. 835616-60-9. Molecular formula: C13H9FN2O4. Mole weight: 276.22. BOC Sciences 9
TC-E 5001 TC-E 5001 is a dual tankyrase (TNKS) inhibitor (Kd = 79 and 28 nM for TNKS1 and TNKS2 respectively, IC50 = 33 nM for TNKS2) that inhibits Wnt signaling and stabilizes Axin2 levels. Synonyms: TC-E 5001; TC E 5001; TCE5001; TCE-5001; TC-E-5001; 3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole. Grades: ≥98% by HPLC. CAS No. 865565-29-3. Molecular formula: C20H19N5O3S. Mole weight: 409.46. BOC Sciences 9
TC-E 5001 TC-E 5001. Group: Biochemicals. Grades: Purified. CAS No. 865565-29-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5002 TC-E 5002. Group: Biochemicals. Grades: Purified. CAS No. 1453071-47-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5002 TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor (IC50 = 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A, respectively) with antitumor activity. It suppresses growth of HeLa and KYSE-150 cancer cells in vitro. Synonyms: TC-E 5002; TC E 5002; TCE 5002; TCE-5002; TCE5002; TC-E-5002; N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine. Grades: ≥98% by HPLC. CAS No. 1453071-47-0. Molecular formula: C15H27NO4. Mole weight: 285.38. BOC Sciences 10
TC-E 5003 TC-E 5003. Group: Biochemicals. Grades: Purified. CAS No. 17328-16-4. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5003 TC-E 5003 is a selective protein arginine methyltransferase 1 ( PRMT1 ) inhibitor with an IC 50 of 1.5 μM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17328-16-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-107574. MedChemExpress MCE
TC-E 5003 TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.5 μM) with no inhibitory effects on CARM1 and Set7/9 methyltransferases. TC-E 5003 inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Synonyms: TC-E 5003; TC E 5003; TCE 5003; TCE-5003; TCE5003; N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide); 4-(2,2-Dichloroacetamido)phenyl sulfone. Grades: ≥98% by HPLC. CAS No. 17328-16-4. Molecular formula: C16H14Cl2N2O4S. Mole weight: 401.26. BOC Sciences 9
TC-E 5005 TC-E 5005 is a potent and selective PDE10A inhibitor (IC50 = 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively, and >5000 nM at PDE1B, 4A, 6, 8A and 9A). TC-E 5005 reverses MK 801-induced hyperactivity and stereotypy in vivo. It also inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate. Synonyms: TC-E 5005; TC E-5005; TC E 5005; TC-E-5005; TCE5005; 2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine. Grades: ≥99% by HPLC. CAS No. 959705-64-7. Molecular formula: C15H18N4O. Mole weight: 270.33. BOC Sciences 10
TC-E 5005 TC-E 5005. Group: Biochemicals. Grades: Purified. CAS No. 959705-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5006 TC-E 5006. Group: Biochemicals. Grades: Purified. CAS No. 1257395-14-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5006 TC-E 5006, also called BIIB042, is a potent γ-secretase modulator, which lowered Aβ42, increased Aβ38, but had little to no effect on Aβ40 levels both in vitro and in vivo. In addition, it did not affect Notch signaling in our in vitro assessment. Aβ42: EC50 = 0.17 μM. Synonyms: TC-E 5006; TCE 5006; TC E 5006; TC-E-5006; TCE5006; 6-[(4-Fluorophenyl)(4-methyl-1-piperidinyl)methyl]-a-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-acetic acid; BIIB042. CAS No. 1257395-14-4. Molecular formula: C29H29F4NO2. Mole weight: 499.54. BOC Sciences 10
TC-E 5007 TC-E 5007. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-E 5007 TC-E 5007 is an irreversible and selective dipeptidyl peptidase 8 and 9 (DPP-8/9) inhibitor (IC50 = 145 and 242 nM, respectively) with selectivity over DPP-IV, DPP-2 and FAP. Synonyms: TC-E 5007; TC E 5007; TCE 5007; TCE-5007; TCE5007; (2S,3R)-2-Amino-1-(1,3-dihydro-2H-isoindol-2-yl)-3-methyl-1-pentanone hydrochloride. Grades: ≥98% by HPLC. CAS No. 1883545-48-9. Molecular formula: C14H20N2O.HCl. Mole weight: 268.78. BOC Sciences 9
TC-E 5008 TC-E 5008 is a selective and cancer-associated mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor (Ki = 120-190 nM), displaying >60-fold selectivity for mIDH1 (found in ~75% of gliomas) over wild type IDH1. TC-E 5008 also inhibits D-2-hydroxyglutaric acid in cells expressing mIDH1 (EC50 = 2.4 μM). Synonyms: 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone; 6-benzyl-1-hydroxy-4-methylpyridin-2-one. CAS No. 50405-58-8. Molecular formula: C13H13NO2. Mole weight: 215.25. BOC Sciences 10
TCEP-d12 Hydrochloride Biochemical tool for selective reduction of disulfide bridges at low pH; reductant for redox assay. Group: Biochemicals. Alternative Names: 3, 3', 3''-Phosphinidynetri spropanoic Acid-d12; Tris(2-carboxyethyl)phosphine-d12 Hydrochloride; Tris (carboxyethyl) phosphine-d12 Hydrochloride. Grades: Highly Purified. CAS No. 1189959-10-1. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
TCEP hydrochloride TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tris(2-carboxyethyl)?phosphine hydrochloride. CAS No. 51805-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W011500. MedChemExpress MCE
TCEP Hydrochloride TCEP Hydrochloride is used for selective reduction of disulfide bridges at low pH. Synonyms: TCEP.HCL; Tris(2-Carboxyethyl)Phosphine Hydrochloride; 3,3',3''-Phosphinetriyltripropanoic acid hydrochloride; TCEP HCl; TCEP; UNII-H49AAM893K; MFCD00145469; TCEP (hydrochloride); Tris(carboxyethyl)phosphine hydrochloride; H49AAM893K; Propanoic acid, 3,3',3''-phosphinidynetris-, hydrochloride. Grades: 98% (AT). CAS No. 51805-45-9. Molecular formula: C9H16ClO6P. Mole weight: 286.65. BOC Sciences
TCEP Hydrochloride Biochemical tool for selective reduction of disulfide bridges at low pH; reductant for redox assay. Group: Biochemicals. Alternative Names: 3, 3', 3''-Phosphinidynetri spropanoic Acid Hydrochloride; Tris(2-carboxyethyl)phosphine Hydrochloride; Tris (carboxyethyl) phosphine Hydrochloride; TCEP·HCl. Grades: Highly Purified. CAS No. 51805-45-9. Pack Sizes: 1g, 5g, 25g. Molecular Formula: C9H15O6P. US Biological Life Sciences. USBiological 3
Worldwide
TC-F 2 TC-F 2. Group: Biochemicals. Grades: Purified. CAS No. 1304778-15-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-F 2 TC-F 2 is a potent, reversible and noncovalent inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 28 and 100 nM for human and rat FAAH, respectively). Synonyms: 1-[(3S)-1-[4-(2-Benzofuranyl)-2-pyrimidinyl]-3-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥99% by HPLC. CAS No. 1304778-15-1. Molecular formula: C26H25N5O2. Mole weight: 439.51. BOC Sciences 10
TCFH A safe, affordable reagent for ester and difficult amide synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Chloro-N,N,N’,N’-tetramethylformamidinium hexafluorophosphate. CAS No. 207915-99-9. Luxembourg Biotechnologies Inc
Luxembourg Bio Technologies
TC-FPR 43 TC-FPR 43. Group: Biochemicals. Grades: Purified. CAS No. 903895-98-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-FPR 43 TC-FPR 43 is a potent formyl peptide receptor 2 (FPR2) agonist (EC50 = 44 nM) that inhibits fMLP- and IL-8-induced neutrophil migration and induces calcium mobilization. TC-FPR 43 was shown to suppress inflammation in a mouse model of acute inflammation. It also acts as an ALX agonist. Synonyms: TCFPR43; TC FPR 43; TC-FPR-43; N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea; Pyrazolone, 1. Grades: ≥98% by HPLC. CAS No. 903895-98-7. Molecular formula: C20H21ClN4O2. Mole weight: 384.86. BOC Sciences 9
TC-G 1000 TC-G 1000 is a potent and orally bioactive α2D-adrenoceptor agonist (Ki = 8.6 pM and 110 nM for rat α2D and α1 receptors respectively, and 25, 26 and 100 nM for human α2A, α2C and α2B receptors respectively). TC-G 1000 displays analgesic activity in a mouse model of abdominal irritation. Synonyms: TC-G 1000; TC G 1000; TCG 1000; TCG1000; 4-(6,7-Dihydro-1,3-dimethylbenzo[c]thien-4-yl)-1H-imidazole maleate. Grades: ≥98% by HPLC. CAS No. 245744-18-7. Molecular formula: C13H14N2S.C4H4O4. Mole weight: 346.4. BOC Sciences 10
TC-G 1000 TC-G 1000. Group: Biochemicals. Grades: Purified. CAS No. 245744-18-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G 1001 TC-G 1001. Group: Biochemicals. Grades: Purified. CAS No. 494191-73-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G 1001 TC-G 1001 is a GPR35 agonist (pEC50 = 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays, respectively) displaying 1000-fold greater potency at human GPR35 receptors than mouse and rat GPR35 orthologs in an IP1 accumulation assay. Synonyms: TC-G 1001; TC G 1001; TCG 1001; TC-G-1001; TCG1001; 4-[[2-[(2-Fluorophenyl)amino]-4-oxo-5(4H)-thiazolylidene]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 494191-73-0. Molecular formula: C17H11FN2O3S. Mole weight: 342.34. BOC Sciences 9
TC-G 1003 TC-G 1003 is a potent and high affinity somatostatin sst2 receptor agonist (Ki = 0.025 nM). TC-G 1003 exhibits an inhibitory effect on growth hormone secretion and attenuates laser-induced ocular neovascular lesion size in rats. Synonyms: TC-G1003; TC G1003; TCG1003; 3-[4-(3-Aminopropoxy)-7-chloro-3-(3,5-dimethylphenyl)-6-quinolinyl]phenol. Grades: ≥98% by HPLC. CAS No. 1021912-42-4. Molecular formula: C26H25ClN2O2. Mole weight: 432.94. BOC Sciences 10
TC-G 1003 TC-G 1003. Group: Biochemicals. Grades: Purified. CAS No. 1021912-42-4. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G 1004 TC-G 1004. Group: Biochemicals. Grades: Purified. CAS No. 1061747-72-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G 1004 TC-G 1004 is a potent and selective A2A antagonist. Synonyms: N-[2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methoxy-1-piperidinyl)-2-pyridinyl]-4-pyrimidinyl]acetamide. CAS No. 1061747-72-5. Molecular formula: C22H27N7O2. Mole weight: 421.5. BOC Sciences 10
TC-G 1005 TC-G 1005 is a potent and selective GPBA agonist (EC50 = 0.72 nM for hTGR5) that selectively activates TGR5 over FXR (farnesoid X receptor). TC-G 1005 has been shown to increase plasma GLP-1 level and lower blood glucose level in mice. Synonyms: TC-G 1005; TC G 1005; TCG 1005; TC-G-1005; TCG1005; (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone. Grades: ≥98% by HPLC. CAS No. 1415407-60-1. Molecular formula: C25H25N3O2. Mole weight: 399.48. BOC Sciences 9
TC-G 1006 TC-G 1006. Group: Biochemicals. Grades: Purified. CAS No. 1324003-64-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G 1008 TC-G 1008. Group: Biochemicals. Grades: Purified. CAS No. 1621175-65-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TC-G-1008 TC-G-1008, also known as GPR39-C3, is a potent and orally available GPR39 agonist (EC50= 0.4 and 0.8 nM for rat and human receptors respectively) with great selectivity for GPR39 over a panel of kinases (IC50s > 10 μM) and displays minimal binding affinity for ghrelin and neurotensin-1 receptors (IC50s > 30 μM). Synonyms: GPR39-C3, GPR39C3, GPR39 C3, TC-G-1008, TC-G1008, TC-G 1008, TCG-1008, TCG1008, TCG 1008; N- [3-chloro-4- [ [ [2- (methylamino) -6-pyridin-2-ylpyrimidin-4-yl] amino] methyl] phenyl] methanesulfonamide; GPR39-C3; N- (3-chloro-4- ( ( (2- (methylamino) -6- (2-pyridinyl) -4-pyrimidinyl) amino) methyl) phenyl) methanesulfonamide; TC-G 1008. CAS No. 1621175-65-2. Molecular formula: C18H19ClN6O2S. Mole weight: 418.9. BOC Sciences 11
TC-G 24 TC-G 24. Group: Biochemicals. Grades: Purified. CAS No. 1257256-44-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide

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