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| Product | Description | |
|---|---|---|
| Tadalafil | 6R-trans)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2'1,6]pyrido[3,4-b]indole-1,4-dione, Cialis. CAS No. 171596-29-5. Product ID: 2-08284. Molecular formula: C22H19N3O4. Mole weight: 389.41. |  |
| Tadalafil | Tadalafil (IC-351) is a PDE5 inhibitor with an IC 50 value of 1.8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IC-351. CAS No. 171596-29-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-90009A. |  |
| Tadalafil | Tadalafil is a PDE-5 inhibitor and medication for the treatment of male sexual function problems (impotence or erectile dysfunction-ED). Synonyms: IC351; Cialis. Grade: 98.0%. CAS No. 171596-29-5. Molecular formula: C22H19N3O4. Mole weight: 389.4. |  |
| Tadalafil | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H19N3O4. CAS No. 171596-29-5. Prepack ID 88434289-5g. Molecular Weight 389.41. See USA prepack pricing. |  |
| Tadalafil-[d3] | Tadalafil-[d3] is the labelled analogue of Tadalafil, which is an inhibitor of phosphodiesterase 5 and can be used to treat erectile dysfunction. Tadalafil is also a phosphodiesterase 5 (PDE5) inhibitor. Synonyms: Tadalafil D3. Grade: 95% by HPLC; 95% atom D. CAS No. 960226-55-5. Molecular formula: C22H16D3N3O4. Mole weight: 392.42. | |
| Tadalafil Impurity 38 | Tadalafil Impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 185750-07-6. Molecular formula: C14H15ClN2O3. Mole weight: 294.74. Catalog: APB185750076. |  |
| Tadalafil Impurity 59 | Tadalafil Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 154030-29-2. Molecular formula: C9H6O5. Mole weight: 194.14. Catalog: APB154030292. | |
| Tadalafil Impurity 77 | Tadalafil Impurity 77. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1220393-12-3. Molecular formula: C22H19N3O5. Mole weight: 405.41. Catalog: APB1220393123. | |
| Tadalafil-methyl-d3 | Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Group: Biochemicals. Alternative Names: Cialis-methyl-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Tadalafil Spiro-2-keto-1,3-oxazine | Tadalafil Spiro-2-keto-1,3-oxazine. Group: Biochemicals. Alternative Names: Tadalafil Impurity. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C22H19N3O6, Molecular Weight: 421.4. US Biological Life Sciences. | Worldwide |
| Tadalafil Spiro-oxindole | Tadalafil Spiro-oxindole. Group: Biochemicals. Alternative Names: Tadalafil Impurity. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C22H19N3O5, Molecular Weight: 405.4. US Biological Life Sciences. | Worldwide |
| TA DNA Polymerase | TA DNA Polymerase. Ta dna polymerase is a mixture of taq dna polymerase with a proofreading 3-5 exonuclease. the fidelity is equal to hifi pfu dna polymerase. the yield is equal to that from taq dna polymerase. it is more suitable for high fidelity ta cloning. ta dna polymerase offers 18-fold fidelity as compared to taq dna polymerase. extension rate is about 1-2 kb/min. template-independentacan be generated at the 3end of the pcr product. amplification of genomic dna fragment up to 8 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3024. |  |
| tadocizumab | Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: tadocizumab. Product Category: Inhibitors. CAS No. 339086-80-5. Purity: 0.96. Product ID: ACM339086805. Alfa Chemistry ISO 9001:2015 Certified. |  |
| TAE-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TAE 684 | TAE 684. Group: Biochemicals. Alternative Names: NVP-TAE 684; NVT TAE-684; 5-Chloro-N2-[2-methoxy-4-[4- (4-methyl-1-piperazinyl) -1-piperidinyl]phenyl]-N4-[2-[ (1-methylethyl) sulfonyl]phenyl]-2, 4-pyrimidinediamine. Grades: Highly Purified. CAS No. 761439-42-3. Pack Sizes: 10mg. Molecular Formula: C30H40ClN7O3S, Molecular Weight: 614.2. US Biological Life Sciences. | Worldwide |
| TAE buffer (50X) | 1lt Pack Size. Group: Biochemicals, Buffers. Formula: N/A. Prepack ID 12439469-1lt. See USA prepack pricing. | |
| TAF1 (1519-1651) human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAF1L (1398-1516) GST tag human | recombinant, expressed in E. coli, ?82% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAF1L (1398-1516) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAF1L (1398-1649) GST tag human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAF1L (1517-1649) GST tag human | recombinant, expressed in E. coli, ?89% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAF1L (1517-1649) His tag human | recombinant, expressed in E. coli, ?79% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TAFA-2 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Tafamidis | Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 594839-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852. | |
| Tafamidis-[d3] | Tafamidis-[d3] is deuterium labelled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, showing comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. Synonyms: Tafamidis-d3; d3-Tafamidis. Molecular formula: C14H4D3Cl2NO3. Mole weight: 311.13. | |
| Tafamidis meglumine | Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fx-1006A. CAS No. 951395-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852A. | |
| Tafasitamab | Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface antigen CD19 [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: XmAb5574; MOR00208; Tafasitamab-cxix. CAS No. 1422527-84-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9981. | |
| Tafenoquine | Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR 238605. CAS No. 106635-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529. | |
| Tafenoquine succinate | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Tafenoquine Succinate | Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR 238605 Succinate. CAS No. 106635-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529A. | |
| Tafetinib | Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibits stem cell factor receptor (Kit) , vascular endothelial growth factor receptor-2 (VEGFR-2) , platelet-derived growth factor receptor-β (PDGFR-β) , glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET) , and Fms-like tyrosine kinase-3 (FLT3) with IC 50 values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation of PDGFR-β and VEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIM010603. CAS No. 1032265-57-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116116. | |
| Tafluposide | Tafluposide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: UNII-QN043X3ZDW; Tafluposide. Product Category: Heterocyclic Organic Compound. CAS No. 179067-42-6. Molecular formula: C45H35F10O20P. Mole weight: 1116.705194 [g/mol]. Purity: 0.96. IUPACName: [(2R,4aR,6R,7R,8S,8aR)-6-[[(5S,5aR,8aR,9R)-9-(3,5-dimethoxy-4-phosphonooxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-5-yl]oxy]-2-methyl-7-[2-(2,3,4,5,6-pentafluorophenoxy)acetyl]oxy-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]d. Density: 1.715g/cm³. Product ID: ACM179067426. Alfa Chemistry ISO 9001:2015 Certified. | |
| Tafluprost | Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn 2+ - mTOR pathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFP-168; MK2452. CAS No. 209860-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0600. | |
| Tafluprost | Tafluprost. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylmethyl Ester; AFP 168; MK 2452; Taflotan; Tapros. Grades: Highly Purified. CAS No. 209860-87-7. Pack Sizes: 2.5mg. Molecular Formula: C25H34F2O5, Molecular Weight: 452.53. US Biological Life Sciences. | Worldwide |
| Tafluprost acid | Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with K i and EC 50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor ( IC 50 =67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFP-172. CAS No. 209860-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0601. | |
| Tafluprost-d7 | Tafluprost-d7. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylmethyl Ester-d7; AFP 168-d7; MK 2452-d7; Taflotan-d7; Tapros-d7. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H27D7F2O5, Molecular Weight: 459.57. US Biological Life Sciences. | Worldwide |
| Tafolecimab | Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IBI-306. CAS No. 2225109-03-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99552. | |
| TAG-1 A2 (78-86) | TAG-1 A2 (78-86). | |
| TAG-2 (42-50) | TAG-2 (42-50). | |
| Tagarafdeg | Tagarafdeg (CFT1946) is an orally active, CRBN-based and mutant-selective bifunctional degradation activating compound (BiDAC) degrader of BRAFV600E with a DC50 of 14 nM in A375 cells. Tagarafdeg is capable of degrading BRAF V600E (Class I), G469A (Class II), G466V (Class III) mutations, and the p61-BRAFV600E splice variant. Tagarafdeg can be used in tumor research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFT1946. CAS No. 2882165-79-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-153341. | |
| Tagatose | Tagatose is a white, anhydrous crystalline solid. It is a carbohydrate, a ketohexose, an epimer of D-fructose inverted at C-4. It can exist in several tautomeric forms. Synonyms: D-lyxo-Hexulose; (3S, 4S, 5R)-2-(hydroxymethyl)oxane-2, 3, 4, 5- tetrol; Naturlose; D-tagatose; tagatosum; tagatoza. CAS No. 87-81-0. Product ID: PE-0495. Molecular formula: C6H12O6. Mole weight: 180.16. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Tagatose; Sweeteners Excipients; Sweetening agent; C6H12O6; 87-81-0; 87-81-0. UNII: T7A20Y888Y. Chemical Name: (3S, 4S, 5R)-1, 3, 4, 5, 6-pentahydroxyhexan-2-one. Administration route: oral and rectal. Dosage Form: oral and rectal solutions. Stability and Storage Conditions: Tagatose is stable under pH conditions typically encountered in foods (pH > 3). It is a reducing sugar and undergoes the Maillard reaction. Tagatose is stable under typical storage conditions. It caramelizes at elevated temperature. Source and Preparation: Tagatose is obtained from D-galactose by isomerization under alkaline conditions in the presence of calcium. Applications: Tagatose is used as a sweetening agent in beverages, foods, and pharmaceutical applications. A 10% solution of tagatose is about 92% as sweet as a 10% sucrose solution.It is a low-calorie sugar with approximately 38% of the calories of sucrose per gram. It occurs naturally in low levels in milk pro |  |
| Tagatose | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Tagatose-6-phosphate | Tagatose-6-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TAGATOSE-6-PHOSPHATE. Product Category: Heterocyclic Organic Compound. CAS No. 136377-13-4. Molecular formula: C6H13O9P. Mole weight: 260.135781. Product ID: ACM136377134. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tagatose-6-phosphate kinase. | |
| tagatose-6-phosphate kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.144. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2974; tagatose-6-phosphate kinase; EC 2.7.1.144; 39434-00-9. Cat No: EXWM-2974. | |
| tagatose-bisphosphate aldolase | Enzyme activity is stimulated by certain divalent cations. It is involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria. Group: Enzymes. Synonyms: D-tagatose-1,6-bisphosphate triosephosphate lyase. Enzyme Commission Number: EC 4.1.2.40. CAS No. 39433-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4876; tagatose-bisphosphate aldolase; EC 4.1.2.40; 39433-95-9; D-tagatose-1,6-bisphosphate triosephosphate lyase. Cat No: EXWM-4876. | |
| tagatose kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.101. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2948; tagatose kinase; EC 2.7.1.101; 39434-00-9. Cat No: EXWM-2948. | |
| tagaturonate reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-altronate:NAD+ 3-oxidoreductase. Other names in common use include altronic oxidoreductase, altronate oxidoreductase, TagUAR, altronate dehydrogenase, and D-tagaturonate reductase. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Enzyme Commission Number: EC 1.1.1.58. CAS No. 9028-45-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0343; tagaturonate reductase; EC 1.1.1.58; 9028-45-9; altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Cat No: EXWM-0343. | |
| Tagette Oil | Tagette Oil. CAS No. 8016-84-0. FEMA No. 3040. Kosher: Y. VIGON Item # 504279. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. |  America & Internationally |
| Tagitanlimab | Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HBM-9167; KL-A167. CAS No. 2417649-97-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99544. | |
| Tagtociclib hydrate | PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3? inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-07104091 hydrate. CAS No. 2733575-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137894A. | |
| Taipehensin-B1 antimicrobial peptide precursor | Taipehensin-B1 antimicrobial peptide precursor is an antibacterial peptide isolated from Hylarana taipehensis. Synonyms: Thr-Met-Lys-Lys-Leu-Leu-Leu-Leu-Phe-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Ser-Ser-Leu-Cys-Glu-Lys-Glu-Arg-Asp-Ala-Asp-Glu-Asp-Glu-Val-Asn-Arg-Gly-Glu-Ala. Grade: >98%. | |
| TAK-071 | TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC 50 of TAK-071 M1R agonist activities is 520 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820812-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122190. | |
| TAK 165 | TAK 165. Group: Biochemicals. Grades: Purified. CAS No. 366017-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK1-IN-2 | TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763213-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132172. | |
| TAK1-IN-3 | TAK1-IN-3 is a potent ATP-competitive TAK1 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 494772-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115743. | |
| TAK1-TAB1 (1-303), (437-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| TAK 21d | TAK 21d. Group: Biochemicals. Grades: Purified. CAS No. 1143578-94-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK-243 | TAK-243 Inhibitor. Uses: Scientific use. Product Category: T16974. CAS No. 1450833-55-2. |  |
| TAK-243 | TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor ( IC 50 =1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN7243. CAS No. 1450833-55-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100487. | |
| TAK-418 | TAK-418 is a selective, orally active LSD1 (KDM1A) enzyme inhibitor with an IC50 of 2.9 nM. TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818252-53-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138830. | |
| TAK-438 | TAK-438 Inhibitor. Uses: Scientific use. Product Category: T2404. CAS No. 1260141-27-2. | |
| TAK-441 | TAK-441 is a highly potent and orally active hedgehog (Hh) signaling inhibitor with an IC 50 value of 4.4 nM. TAK-441 has strong antitumor activity in solid tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1186231-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16475. | |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grade: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. | |
| TAK-448 acetate | It is an agonist of KISS1R protein, and is an oligopeptide analogue of kisspeptin. Synonyms: MVT-602 (acetate); Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg (Me)-Trp-NH2 acetate; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide acetate (1:1). Grade: ≥98%. CAS No. 1470374-22-1. Molecular formula: C58H80N16O14.C2H4O2. Mole weight: 1285.41. | |
| TAK-475 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TAK-632 | TAK-632 is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAFV600E, BRAFWT, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228591-30-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15767. | |
| TAK 715 | TAK 715. Group: Biochemicals. Grades: Purified. CAS No. 303162-79-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK-715 | TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38? and p38?, respectively. TAK-715 inhibits casein kinase I (CK1?/?) to regulate activation of Wnt/?-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303162-79-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10456. | |
| TAK-715 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TAK-733 | TAK-733 is a potent and selective MEK allosteric site inhibitor with an IC50 of 3.2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1035555-63-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13449. | |
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