A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Tamra, PMAP-36 (12-36) is a derivative of PMAP-36 (12-36), a fragment of PMAP-36. PMAP-36 is an antimicrobial peptide produced by Sus scrofa (Pig). It has antimicrobial activity against Gram-negative and Gram-positive bacteria. Synonyms: Tamra-Lys-Arg-Leu-Lys-Lys-Ile-Gly-Lys-Val-Leu-Lys-Trp-Ile-Pro-Pro-Ile-Val-Gly-Ser-Ile-Pro-Leu-Gly-Cys-Gly. Molecular formula: C153H244N36O32S. Mole weight: 3132.00.
Tamra, PMAP-36 (16-36)
Tamra, PMAP-36 (16-36) is a derivative of PMAP-36 (16-36), a fragment of PMAP-36. PMAP-36 is an antimicrobial peptide produced by Sus scrofa (Pig). It has antimicrobial activity against Gram-negative and Gram-positive bacteria. Synonyms: Tamra-Lys-Ile-Gly-Lys-Val-Leu-Lys-Trp-Ile-Pro-Pro-Ile-Val-Gly-Ser-Ile-Pro-Leu-Gly-Cys-Gly. Molecular formula: C129H197N27O28S. Mole weight: 2606.30.
Tamra, PMAP-36 (7-36)
Tamra, PMAP-36 (7-36) is a derivative of PMAP-36 (7-36), a fragment of PMAP-36. PMAP-36 is an antimicrobial peptide produced by Sus scrofa (Pig). It has antimicrobial activity against Gram-negative and Gram-positive bacteria. Synonyms: Tamra-Arg-Lys-Lys-Thr-Arg-Lys-Arg-Leu-Lys-Lys-Ile-Gly-Lys-Val-Leu-Lys-Trp-Ile-Pro-Pro-Ile-Val-Gly-Ser-Ile-Pro-Leu-Gly-Cys-Gly. Molecular formula: C181H299N49O38S. Mole weight: 3801.90.
Tamrintamab
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 ( DPEP3 or MBD3 ). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SC-003 mAb; SC-Mab003; SC34.28ss1. CAS No. 2148325-59-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99506.
Tamsulosin
Tamsulosin ((R)-(-)-YM12617 free base) is an orally active antagonist of α 1 -adrenergic receptor. Tamsulosin induces Apoptosis. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-YM12617 free base; LY253351 free base. CAS No. 106133-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0661.
Tamsulosin
Tamsulosin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106133-20-4. Molecular formula: C20H28N2O5S. Mole weight: 408.51. Catalog: APB106133204.
Tamsulosin-D4
Tamsulosin-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1231943-97-7. Molecular formula: C20H24D4N2O5S. Mole weight: 412.54. Catalog: APB1231943977.
Tamsulosin-[d4] hydrochloride
One of the labelled form of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Synonyms: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide-D4 hydrochloride; YM 617-d4; Yutanal-d4. Grade: ≥90%. Molecular formula: C20H25D4ClN2O5S. Mole weight: 449.00.
Tamsulosin EP Impurity E
Tamsulosin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105764-07-6. Molecular formula: C8H9NO4S. Mole weight: 215.22. Catalog: APB105764076.
Tamsulosin EP Impurity G
Tamsulosin EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106138-88-9. Molecular formula: C20H28N2O5S. Mole weight: 408.51. Catalog: APB106138889.
Tamsulosin EP Impurity H
Tamsulosin EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329611-47-3. Molecular formula: C20H27NO3. Mole weight: 329.44. Catalog: APB1329611473.
Tamsulosin hydrochloride
Tamsulosin hydrochloride ((R)-(-)-YM12617 free base) is an orally active antagonist of α 1 -adrenergic receptor. Tamsulosin hydrochloride induces Apoptosis. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-YM12617; LY253351. CAS No. 106463-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0661A.
A selective alpha-1A adrenoceptor antagonist that has preferential selectivity for the alpha-1A adrenoceptor in the prostate versus the alpha-1B adrenoceptor in the blood vessels (pKi values are 9.97, 9.64 and 8.86 for alpha-1A, alpha-1B and alpha-1D subtypes respectively). Used for treatment of difficult urination, a common symptom of enlarged prostate. Has negligible effect on arterial blood pressure in vivo. Group: Biochemicals. Alternative Names: LY-253351, YM-12617-1, YM-617, Flomax, Harnal, Omnic, Pradif5- [ (2R) -2- [ [2- (-Ethoxyphenoxy) ethyl] amino] propyl ] -2-methoxy Benzene sulfonamide hydrochloride. Grades: Highly Purified. CAS No. 106463-17-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Tamsulosin Impurity 5
Tamsulosin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1027854-97-2. Molecular formula: C27H34N2O5S. Mole weight: 498.64. Catalog: APB1027854972.
TAN
Spectrophotometric reagent for transition metals. Group: Uv/visible (uv/vis) spectroscopy. Alternative Names: 1-(2-Thiazolylazo)-2-naphthol.
TAN-1030A
TAN-1030A is an indolocarbazole derivative produced by Streptomyces sp. C-71799. It can activate macrophage in mice. Synonyms: TAN 1030A. CAS No. 126221-76-9. Molecular formula: C27H22N4O4. Mole weight: 466.5.
TAN-1057A
TAN-1057A is an antibiotic produced by Flexibacter sp. PK-74 and PK-176. It is active against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. It inhibited protein biosynthesis in Escherichia coli and S. aureus. Synonyms: Antibiotic TAN 1057A; TAN 1057A. CAS No. 128126-44-3. Molecular formula: C13H25N9O3. Mole weight: 355.4.
TAN-1057B
TAN-1057B is an antibiotic produced by Flexibacter sp. PK-74 and PK-176. It is active against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. Synonyms: Antibiotic TAN 1057B; TAN 1057B. CAS No. 128126-45-4. Molecular formula: C13H25N9O3. Mole weight: 355.4.
TAN-1057C
TAN-1057C is an antibiotic produced by Flexibacter sp. PK-74 and PK-176. It is active against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. Synonyms: Antibiotic TAN 1057C; TAN 1057C. Molecular formula: C13H25N9O3. Mole weight: 355.4.
TAN-1057D
TAN-1057D is an antibiotic produced by Flexibacter sp. PK-74 and PK-176. It is active against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. Synonyms: Antibiotic TAN 1057D; TAN 1057D. CAS No. 128126-47-6. Molecular formula: C13H25N9O3. Mole weight: 355.4.
TAN-1120
TAN-1120 is an anthracycline produced by Streptomyces triangulates subsp. Angiostaticus. It showed remarkably potent angiostatic activity in two conventional angiogenesis assay systems in vivo. Synonyms: TAN 1120. CAS No. 131443-34-0. Molecular formula: C34H41NO13. Mole weight: 671.7.
TAN-1323C
TAN-1323C is a concanamycin-group antibiotic produced by Streptomyces purpurascens. It showed remarkably potent angiostatic activity in the chick chorioallantoic membrane (CAM) assay. Synonyms: TAN 1323C. Molecular formula: C45H74O14. Mole weight: 839.1.
TAN-1323D
TAN-1323D is a concanamycin-group antibiotic produced by Streptomyces purpurascens. It showed remarkably potent angiostatic activity in the chick chorioallantoic membrane (CAM) assay. Synonyms: TAN 1323D. Molecular formula: C43H66O13. Mole weight: 791.
TAN 1364B
TAN 1364B is a tetronic acid analogue isolated from Streptomyces species. It can inhibit protein tyrosine phosphatase, phospholipase A2, heparinase and HIV-1 protease. Synonyms: CI 010, 3-hexadecanoyl-5-hydroxymethyltetronic acid. Grade: >95% by HPLC. CAS No. 154639-24-4. Molecular formula: C21H36O5. Mole weight: 368.51.
TAN-1496A
TAN-1496A is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. It inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN 1496A. Molecular formula: C22H28N2O9S2. Mole weight: 528.6.
TAN-1496C
TAN-1496C is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN 1496C. Molecular formula: C22H28N2O9S3. Mole weight: 560.7.
TAN-1496D
TAN-1496D is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN 1496D. Molecular formula: C18H24N2O7S2. Mole weight: 444.5.
TAN-1496E
TAN-1496E is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN 1496E. Molecular formula: C22H28N2O9S4. Mole weight: 592.7.
TAN-1511A
TAN-1511A is a lipopeptide antibiotic isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. It induced the secretion of both granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF). Synonyms: TAN 1511A. Molecular formula: C71H129N7O17S. Mole weight: 1384.9.
TAN-1511B
TAN-1511B is a lipopeptide antibiotic isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. It induced the secretion of both granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF). Synonyms: TAN 1511B. Molecular formula: C70H126N8O17S. Mole weight: 1383.9.
TAN-1511C
TAN-1511C is a lipopeptide antibiotic isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. It induced the secretion of both granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF). Synonyms: TAN 1511C. Molecular formula: C72H129N7O15S. Mole weight: 1364.9.
TAN-1518A
TAN-1518A is a naphthacenecarboxamide antibiotic isolated from a culture broth of Streptomyces sp. AL-16012. It inhibits DNA topoisomerase I. Synonyms: TAN 1518A. Molecular formula: C39H41NO15. Mole weight: 763.7.
TAN-1518B
TAN-1518B is a naphthacenecarboxamide antibiotic isolated from a culture broth of Streptomyces sp. AL-16012. It inhibits DNA topoisomerase I. Synonyms: TAN 1518B. CAS No. 154163-87-8. Molecular formula: C41H45NO15. Mole weight: 791.8.
TAN-1813
TAN-1813 is a Ras-farnesyltransferase inhibitor produced by a fungus strain, FL-41510. It inhibited rat brain farnesyltransferase and geranylgeranyltransferase I activity with IC50 values of 23 and 47 μg/mL, respectively. It also inhibited the proliferation of various human cancer cells. Synonyms: TAN 1813. Molecular formula: C26H35NO6. Mole weight: 457.6.
TAN 420C
TAN-420C is an antibiotic produced by Streptomyces hygroscopicus. TAN 420C is known to exhibit antitumour activity. Synonyms: Dihydroherbimycin C. Grade: >95% by HPLC. CAS No. 91700-91-3. Molecular formula: C29H42N2O9. Mole weight: 562.65.
TAN 420E
Antibiotic TAN 420E is a hydroquinone analogue of herbimycin A with antibacterial, antifungal and antiprotozoan activity. Synonyms: Dihydro-Herbimycin A; Dihydroherbimycin A. Grade: >95% by HPLC. CAS No. 91700-93-5. Molecular formula: C30H44N2O9. Mole weight: 576.68.
TAN-931
TAN-931 is a nonsteroidal aromatase inhibitor produced by Penicillium funiculosum No. 8974. Synonyms: Tan-931; Tan 931. CAS No. 127448-92-4. Molecular formula: C15H10O7. Mole weight: 302.23.
TAN-950A
TAN-950A is an antifungal produced by Streptomyces platensis A-136. It is effective against Candida with MIC of 0.78-3.13 μg/mL. Synonyms: TAN 950A; TAN-950 A. Molecular formula: C6H8N2O4. Mole weight: 172.14.
TAN-999
TAN-999 is an indolocarbazole derivative produced by Streptomyces sp. C-71799. It can activate macrophage in mice. Synonyms: TAN 999. CAS No. 124843-68-1. Molecular formula: C29H26N4O4. Mole weight: 494.5.
Tanacetum vulgare, ext.
25g Pack Size. Group: Analytical Reagents, Aroma Chemicals, Biochemicals, Building Blocks, Flavours and Fragrance Materials. Formula: N/A. CAS No. 84961-64-8. Prepack ID 90028843-25g. See USA prepack pricing.
Tanaproget
Tanaproget is an orally effective, selective nonsteroidal progesterone receptor (PR) agonist targeting human PR with an IC50 of 1.7 nM. Tanaproget promotes the interaction between PR receptors and coactivators (such as SRC-1), thereby inhibiting the secretion of matrix metalloproteinases (MMP-3/MMP-7) and reducing endometrial tissue invasion and angiogenesis. Tanaproget can be used for contraception and endometriosis inhibition research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSP-989. CAS No. 304853-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15606.
Tandospirone
Tandospirone. Group: Biochemicals. Alternative Names: (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione. Grades: Highly Purified. CAS No. 87760-53-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C21H29N5O2. US Biological Life Sciences.
Worldwide
Tandospirone
Tandospirone (SM-3997) is a potent and selective 5-HT 1A receptor partial agonist, with a K i of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-3997. CAS No. 87760-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14558.
Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-3997 citrate. CAS No. 112457-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0061.
Tandospirone hydrochloride
Tandospirone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 99095-10-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Tandospirone Impurity 12
Tandospirone Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aR,4S,7R,7aS)-2-(4-(piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione. CAS No. 105981-33-7. Molecular formula: C17H27N3O2. Mole weight: 305.42. Catalog: APB105981337.
Tandutinib
Tandutinib (MLN518) is a potent and selective inhibitor of the FLT3 with an IC 50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC 50 s of 0.17 μM and 0.20 μM, respectively. Tandutinib can be used for acute myelogenous leukemia (AML) [1] [2]. Tandutinib has the ability to cross the blood-brain barrier [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN518; CT53518. CAS No. 387867-13-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10202.
Tandutinib
An oral, small-molecule inhibitor of FLT3 for the treatment of AML (acute myelogenous leukemia). Group: Biochemicals. Alternative Names: 4-[6-Methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-. Grades: Highly Purified. CAS No. 387867-13-2. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Tandutinib hydrochloride
Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC 50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC 50 s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML) [1] [2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN518 hydrochloride; CT53518 hydrochloride. CAS No. 2438900-70-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10202A.
Tanespimycin
Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC 50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 [1] [5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-AAG; NSC 330507; CP 127374. CAS No. 75747-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg. Product ID: HY-10211.
Tanezumab
Tanezumab (RN-624) is a humanized anti- NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA , in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RN-624; PF 4383119. CAS No. 880266-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99221.
Tangeretin, a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities. Tangeretin can be used in health products. Synonyms: Tangeritin. Grade: >98%. CAS No. 481-53-8. Molecular formula: C20H20O7. Mole weight: 372.37.
Tangeretin
Tangeretin. Group: Biochemicals. Grades: Highly Purified. CAS No. 481-53-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H20O7. US Biological Life Sciences.
Worldwide
Tangeretin
Tangeretin - Product ID: NST-10-43. Category: Flavonoids. Alternative Names: 4',5,6,7,8-Pentamethoxyflavone. Purity: 98%. Test method: HPLC. CAS No. 481-53-8. Pack Sizes: 0,5g, 1g, 2,5g, 5g. Appearance: White to beige coloured Powder. Molecular formula: C20H20O7. Mole weight: 372.37. Storage: +2 +8 °C.
Tangeretin
Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: Tangeritin; NSC53909; NSC618905. CAS No. 481-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0133.
Tangerine Peel Extract. Applications: Used for health care products, dietary supplements, herb medecine. Group: Others. Synonyms: Tangerine Peel Extract; Citrus reticulata L. Purity: 10:1 by TLC. Appearance: Brown-yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Peel. Species: Citrus reticulata L. Tangerine Peel Extract; Citrus reticulata L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-144.
Tangerine Terpenes
Tangerine Terpenes. CAS No. 68608-38-8. Kosher: Y. VIGON Item # 500607. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Tangerine Water Phase
Water Phase Aroma. Uses: Flavors, Fragrances, Aroma Therapy. Group: Essences. Grade: Food. Pack Sizes: Pails to Drums.
Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC 50 s of 8-530 nM. Taniborbactam hydrochloride has IC 50 s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VNRX-5133 hydrochloride. CAS No. 2244235-49-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109124A.
Tanimilast
Tanimilast (CHF-6001) is a novel highly potent and selective phosphodiesterase 4 inhibitor( IC 50 =0.026 ± 0.006 nM) with robust anti-inflammatory activity and suitable for topical pulmonary administration.Tanimilast is used for the research of obstructive lung diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHF-6001. CAS No. 1239278-59-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19929.
Tankyrase1/2 Inhibitor III - CAS 865565-29-4
The Tankyrase1/2 Inhibitor III controls the biological activity of Tankyrase1/2. Group: Fluorescence/luminescence spectroscopy.
Tankyrase1/2 Inhibitor III (TNKS1/2 Inhibitor III, Wnt Pathway Inhibitor XIV, 3-(4-Methoxyphenyl)-5-((4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-ylthio)methyl)-1,2,4-oxadiazole)
A cell-permeable triazolylthiomethyl-oxadiazole compound that binds TNKS1/PARP5a and TNKS2/PARP5b with high affinity (=79 and 28nM, respectively), and acts as a potent and reversible TNKS1/2 dual inhibitor (IC50=33nM TNKS2 in an auto-PARsylation assay). Shown to interact with the adenosine diphosphate linker portion of the NAD+ donor site, and display excellent selectivity over PARP1 and PARP2 activities (IC50>19uM); stabilize Axin2 levels (EC50=709nM in SW480 cells), and antagonize Wnt signaling (IC50=215nM in HEK293-SuperTopFlash assay). Exhibits minimal activity towards cytochrome P450 enzymes (IC50=21 and 5.7uM for CYP2C9 and CYP3A4) and hERG ion channel (IC50>30uM), and adequate microsomal stability. Group: Biochemicals. Grades: Highly Purified. CAS No. 865565-29-4. Pack Sizes: 10mg. US Biological Life Sciences.