A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency (IC50s = 2.9 and 16.2 μM, respectively). Uses: For research used only. Synonyms: Mereletinib; EGFR inhibitor; AZD9291; AZD 9291. Grades: 98%. CAS No. 1421373-65-0. Molecular formula: C28H33N7O2. Mole weight: 499.61.
AZD9291DA
AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. Uses: For research used only. Synonyms: AZD9291-Des acryl analogue; AZD9291 Des acryl precursor; Mutated EGFR-IN-1; N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine; N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-N4-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine; SCHEMBL14660679. Grades: 0.98. CAS No. 1421372-66-8. Molecular formula: C25H31N7O. Mole weight: 445.571.
AZD-9291 mesylate
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines. Synonyms: Mereletinib mesylate; EGFR inhibitor; AZD9291 mesylate; AZD 9291 mesylate. Grades: >98%. CAS No. 1421373-66-1. Molecular formula: C29H37N7O5S. Mole weight: 595.71.
AZD9291 Osimertinib Impurity 3
AZD9291 Osimertinib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-N-(3-((2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-3-oxopropyl)acryl. CAS No. 2919324-18-6. Molecular Formula: C56H66N14O4. Mole Weight: 999.21. Catalog: APB2919324186.
AZD9496
AZD9496 is an effective, selective estrogen receptor ( ERα ) antagonist with an IC 50 of 0.28 nM. AZD9496 is an orally active, selective estrogen receptor degrader (SERD). Uses: Scientific research. Group: Signaling pathways. CAS No. 1639042-08-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12870.
AZD9496
AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Synonyms: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; AZD9496; AZD-9496; AZD 9496. Grades: 98%. CAS No. 1639042-08-2. Molecular formula: C25H25F3N2O2. Mole weight: 442.48.
AZD9496 maleate
AZD9496 maleate is potent downregulator of estrogen receptor in breast carcinoma cells and also antagonise ERα with good oral pharmacokinetic properties. It is in collaboration with parexel initiates enrolment in a phase I trial in health volunteers in US. Synonyms: (Z)-but-2-enedioic acid;(E)-3-[3,5-difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acidAZD9496 (maleate); AZD 9496 (maleate); AZD-9496 (maleate). CAS No. 1639042-28-6. Molecular formula: C29H29F3N2O6. Mole weight: 558.55.
AZD9496 maleate
AZD9496 maleate is a potent and selective estrogen receptor ( ERα ) antagonist with IC 50 of 0.28 nM. AZD9496 maleate is an orally bioavailable selective oestrogen receptor degrader (SERD). Uses: Scientific research. Group: Signaling pathways. CAS No. 1639042-28-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12870A.
Az-ddCTP-10 mM aqueous solution is an aqueous solution constituted by Azido-deoxy Cytidine Triphosphate (Az-ddCTP), which is a remarkable nucleotide analog. This solution empowers researchers in virology and antiviral drug development by effectively hindering viral replication. By seamlessly incorporating itself into the viral DNA chain during replication is az-ddCTP orchestrates premature termination, thereby rendering it an indispensable tool in this scientific domain. Synonyms: 3'-Azido-ddCTP.Li; 3'-Azido-2',3'-dideoxycytidine-5'-triphosphate lithium salt; AZddCTP. Grades: 90%. Molecular formula: C9H15O12N6P3·xLi. Mole weight: 492.17 (free acid).
AzddMeC
AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1 -infected human PBM cells and HIV-1 -infected human macrophages, the EC 50 values of AzddMeC are 9 nM and 6 nM, respectively [1] [2]. AzddMeC is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS-92. CAS No. 87190-79-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105268.
Az-ddTTP-100 mM aqueous solution
Az-ddTTP-100 mM aqueous solution is an indispensable and highly regarded recompound within the biomedical realm, emerging as a pivotal tool revolutionizing DNA sequencing methodologies. This superlative solution facilitates the meticulous investigation and research of multifaceted afflictions encompassing malignant neoplasms and hereditary maladies. Synonyms: 3'-Azido-ddTTP.Li; 3'-Azido-2',3'-dideoxythymidine-5'-triphosphate lithium salt; AzddTTP. Grades: 98%. Molecular formula: C10H16N5O13P3·xLi. Mole weight: 507.18 (free acid).
Az-ddUTP-100 mM aqueous solution
Az-ddUTP-100 mM aqueous solution is a valuable tool in biomedical research acting as a substrate for reverse transcriptase to facilitate the introduction of azide-modified deoxyuridine triphosphate (ddUTP) into cDNA. This compound enables efficient labeling of RNA transcripts during in vitro transcription reactions. It finding applications in drug discovery, gene expression analysis is and understanding diseases at the molecular level. Synonyms: 3'-Azido-ddUTP.Li; 3'-Azido-2',3'-dideoxyuridine-5'-triphosphate lithium salt; AzddUTP. Molecular formula: C9H14N5O13P3·xLi. Mole weight: 493.15 (free acid).
AZ Dyrk1B 33
AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 value of 7 nM. It shows better selectivity than AZ 191 and shows no off-target effects against a panel of 124 kinases tested. It displays distinct cellular effects when compared to DYRK1B knockdown through siRNA and has been demonstrated cellular in vitro activity. Synonyms: AZ-Dyrk1B-33; 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine. Grades: ≥98% by HPLC. CAS No. 1679330-37-0. Molecular formula: C19H16N4. Mole weight: 300.36.
a-Zearalenol
a-Zearalenol. Group: Biochemicals. Alternative Names: (3S,7R,11E)-3,4,5,6,7,8,9,10-Octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one. Grades: Highly Purified. CAS No. 36455-72-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H24O5. US Biological Life Sciences.
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Azelaic acid
Azelaic acid, produced by ozone cracking of unsaturated fatty acid, could be commonly used in grease, cosmetics and pharmaceuticals. Uses: Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals. Synonyms: Finacea; Anchoic acid. Grades: > 98 %. CAS No. 123-99-9. Molecular formula: C9H16O4. Mole weight: 188.22.
Azelaic acid
100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: HOOC(CH2)7COOH. CAS No. 123-99-9. Prepack ID 31437119-100g. Molecular Weight 188.22. See USA prepack pricing.
Azelaic acid
Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nonanedioic acid. CAS No. 123-99-9. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-B0704.
Azelaic acid
Azelaic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-99-9. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C9H16O4. US Biological Life Sciences.
Worldwide
Azelaic Acid
analytical standard. Uses: For analytical and research use. Group: Flavor and fragrance standards; api standards; pharmaceutical toxicology. Grades: analytical standard. CAS No. 123-99-9. Pack Sizes: 100MG. IUPAC Name: nonanedioic acid. Molecular Formula: C9H16O4. Mole Weight: 188.22. EC Number: 204-669-1. Catalog: APS123999A. Assay: ≥98.5% (GC). SMILES: OC(=O)CCCCCCCC(=O)O. Format: Neat. Shipping: Room Temperature.
Azelaic Acid
Azelaic acid is a synthetic dicarboxylic acid that is commonly used in the treatment of acne and rosacea. It is also sometimes prescribed for other skin conditions, such as hyperpigmentation and melasma. Azelaic acid works by inhibiting the growth of acne-causing bacteria on the skin, reducing inflammation, and helping to unclog pores. It is also a mild exfoliant, which helps to remove dead skin cells and improve skin texture. Uses: 1. treatment of acne: azelaic acid is commonly used as a topical treatment for mild to moderate acne. it works by reducing the growth of bacteria that causes acne, and it also helps to unclog pores and reduce inflammation. 2. treatment of rosacea: azelaic acid also has anti-inflammatory properties that make it an effective treatment for rosacea, a chronic skin condition that causes facial redness. Group: Resin additives. Alternative Names: Anchoec acid. CAS No. 123-99-9. Product ID: Nonanedioic acid. Molecular formula: 188.22. Mole weight: C9H16O4. C(CCCC(=O)O)CCCC(=O)O. InChI=1S/C9H16O4/c10-8 (11)6-4-2-1-3-5-7-9 (12)13/h1-7H2, (H, 10, 11) (H, 12, 13). BDJRBEYXGGNYIS-UHFFFAOYSA-N. 98%.
Azelaic Acid
Azelaic Acid. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
California
Azelaic acid-[13C2]
Azelaic acid-[13C2] is a labelled compound of Azelaic acid. Azelaic acid, produced by ozone cracking of unsaturated fatty acid, could be commonly used in grease, cosmetics and pharmaceuticals. Synonyms: (1,9-13C2)nonanedioic acid. Grades: > 98%. Molecular formula: C7[13C]2H16O4. Mole weight: 190.21.
Azelaic acid-[13C9]
Azelaic acid-[13C9] is a labelled analogue of Azelaic acid, a bioactive molecule used in treating acne and other skin disorders. Synonyms: Azelaic acid-13C9; Nonanedioic-13C9 Acid. Grades: 98% (CP); 99% atom 13C. CAS No. 1262769-57-2. Molecular formula: [13C]9H16O4. Mole weight: 197.15.
Azelaic Acid 2-Ethylhexyl Ester
Azelaic Acid 2-Ethylhexyl Ester is an ester of Azelaic acid (A808140), an antiacne agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 13050-58-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H32O4, Molecular Weight: 300.43. US Biological Life Sciences.
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Azelaic Acid 2-Ethylhexyl Ester-d17
Azelaic Acid 2-Ethylhexyl Ester-d17 is labelled Azelaic Acid 2-Ethylhexyl Ester (A808180) which is an ester of Azelaic acid (A808140), an antiacne agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C17H16D16O4, Molecular Weight: 316.529999999999. US Biological Life Sciences.
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Azelaic Acid 98.5%
Azelaic Acid is a saturated dicarboxylic acid that exists as a white powder. It is commonly derived from natural ingredients such as wheat, rye, and barley. Uses: Anti-acne, Anti-inflammatory, Anti-bacterial, Anti-oxidant. Group: Skin Care Active Ingredients. INCI Name: Azelaic Acid. CAS Number: 123-99-9.
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Azelaic acid 99+%
Azelaic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg, 5Kg. US Biological Life Sciences.
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Azelaic Acid 99% HPLC
Azelaic Acid 99% HPLC.
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Azelaic acid dichloride
Azelaic acid dichloride (CAS# 123-98-8) is a useful research chemical. Synonyms: nonanedioyl dichloride. Grades: 95 %. CAS No. 123-98-8. Molecular formula: C9H14Cl2O2. Mole weight: 225.11.
Azelaic acid, Flake form
100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Organics. Formula: HO2C(CH2)7CO2H. CAS No. 123-99-9. Prepack ID 90028396-100g. Molecular Weight 188.22. See USA prepack pricing.
Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles, which contain low molecular weight species. It is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Synonyms: 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine; C16-09:0 (COOH) PC; 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine. Grades: >99%. CAS No. 354583-69-0. Molecular formula: C33H66NO9P. Mole weight: 651.85.
Azelastine
Azelastine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one. CAS No. 58581-89-8. Molecular Formula: C22H24ClN3O. Mole Weight: 381.90. Catalog: APB58581898.
Azelastine
Azelastine, a phthalazine derivative, is a potent, second-generation, selective, histamine antagonist used as a first line therapy of mild intermittent. Uses: An antihistamine and mast cell stabilizer. Synonyms: 1(2h)-phthalazinone,4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1h-azepin; 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one. Grades: ≥98%. CAS No. 58581-89-8. Molecular formula: C22H24ClN3O. Mole weight: 381.9.
Azelastine-13C,d3
Orally active H1-hystamine receptor antagonist. Antihistaminic. Group: Biochemicals. Alternative Names: 4-[(4-Chlorophenyl)methyl]-2-[hexahydro-1-(methyl-13C,d3)-1H-azepin-4-yl]-1(2H)-phthalazinone. Grades: Highly Purified. CAS No. 758637-88-6. Pack Sizes: 1mg. US Biological Life Sciences.
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Azelastine-13C,d3 N-Oxide (Mixture of Diastereomers)
A labeled metabolite of Azelastine. Group: Biochemicals. Alternative Names: 4-[(4-Chlorophenyl)methyl]-2-[hexahydro-1-(methyl-13C,d3)-1-oxido-1H-azepin-4-yl]-1(2H)-phthalazinone. Grades: Highly Purified. CAS No. 1346602-76-3. Pack Sizes: 1mg. US Biological Life Sciences.
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Azelastine EP Impurity A
Azelastine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: benzohydrazide. CAS No. 613-94-5. Molecular Formula: C7H8N2O. Mole Weight: 136.15. Catalog: APB613945.
Azelastine EP Impurity B
Azelastine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 110406-94-5. Molecular Formula: C14H21N3O. Mole Weight: 247.34. Catalog: APB110406945.
Azelastine EP Impurity C
Azelastine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-(4-chlorophenyl)acetyl)benzoic acid. CAS No. 53242-76-5. Molecular Formula: C15H11ClO3. Mole Weight: 274.7. Catalog: APB53242765.
Azelastine EP Impurity D
Azelastine EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-chlorobenzyl)phthalazin-1(2H)-one. CAS No. 53242-88-9. Molecular Formula: C15H11ClN2O. Mole Weight: 270.71. Catalog: APB53242889.
Azelastine EP Impurity E
Azelastine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20526-97-0. Molecular Formula: C15H9ClO2. Mole Weight: 256.69. Catalog: APB20526970.
Azelastine EP Impurity E
Azelastine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3-(4-chlorobenzylidene)isobenzofuran-1(3H)-one. CAS No. 105279-16-1. Molecular Formula: C15H9ClO2. Mole Weight: 256.68. Catalog: APB105279161.
Azelastine EP Impurity F
Azelastine EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-(4-chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide. Molecular Formula: C22H24ClN3O2. Mole Weight: 397.9. Catalog: APB02936.
Azelastine HCl
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Uses: Histamine antagonist. Synonyms: ZELASTINE HYDROCHLORIDE; AC1Q1SYE; HYDROGEN AZELASTINE CHLORIDE; AKOS026749829; DR002552. Grades: >98%. CAS No. 79307-93-0. Molecular formula: C22H25Cl2N3O. Mole weight: 418.36.
Azelastine HCl Impurity B
Azelastine HCl Impurity B is an intermediate in the preparation of Azelastine. Synonyms: Azelastine Related Compound B; 1-Methyl-4-(2-benzoylhydrazino)azapan hydrochloride; N'-(1-Methylazepan-4-yl)benzohydrazide hydrochloride; Benzoic acid 2-(hexahydro-1-methyl-1H-azepin-4-yl)hydrazide hydrochloride. Grades: > 95%. CAS No. 117078-69-0. Molecular formula: C14H22N3OCl. Mole weight: 283.80.
Azelastine hydrochloride
Azelastine hydrochloride. Group: Biochemicals. Alternative Names: 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloride; Afluon; Allergodil. Grades: Highly Purified. CAS No. 79307-93-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H25Cl2N3O. US Biological Life Sciences.
Worldwide
Azelastine hydrochloride
Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2. Group: Inhibitors. Alternative Names: a5610;azeptin;e-0659;w-2979m;AZELASTINE HCL;AZELASTINE HYDROCHLORIDE;4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride. CAS No. 79307-93-0. Molecular formula: C22H25Cl2N3O. Mole weight: 418.36. Purity: 0.9993. Catalog: ACM79307930.
Azelastine hydrochloride
Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H 1 ) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79307-93-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-B0462.