A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Azelastine Impurity C is an impurity of Azelastine. Synonyms: 2-((4-Chlorophenyl)acetyl)benzoic acid; 2-[2-(4-Chlorophenyl)acetyl]benzoic acid; Einecs 258-444-8. Grades: > 95%. CAS No. 53242-76-5. Molecular formula: C15H11ClO3. Mole weight: 274.71.
Azelastine Impurity D
Azelastine Impurity D serves as an impurity standard of azelastine, a drug commonly prescribed to treat allergic rhinitand conjunctivitis. Grades: > 95%. CAS No. 53242-89-9. Molecular formula: C15H11ClN2O. Mole weight: 270.72.
Azelastine Impurity E
Azelastine Impurity E is an impurity arising in the synthesis of azelastine. It is a stilbene-related benzalphthalide derivative with with potential anti-HIV and leishmanicidal activity. Synonyms: 3-[(4-chlorophenyl)methylene]phthalide; 3-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-3H-isobenzofuran-1-one; 3-(4-Chlorobenzal)phthalide; 4-Chlorobenzylidene phthalide. Grades: > 95%. CAS No. 20526-97-0. Molecular formula: C15H9ClO2. Mole weight: 256.69.
Azelastine N-Oxide
Azelastine N-Oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 640279-88-5. Molecular Formula: C22H24ClN3O2. Mole Weight: 397.9. Catalog: APB640279885.
Azelastine-N-Oxide
Azelastine-N-Oxide is a metabolite of Azelastine. Synonyms: Azelastine N-Oxide (Mixture of DiastereoMers); 4-[(4-Chlorophenyl)Methyl]-2-(hexahydro-1-Methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone. Grades: > 95%. CAS No. 640279-88-5. Molecular formula: C22H24ClN3O2. Mole weight: 397.91.
Azelastine N-Oxide (Mixture of Diastereomers)
A metabolite of Azelastine. Group: Biochemicals. Alternative Names: 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone. Grades: Highly Purified. CAS No. 640279-88-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C22H24ClN3O2, Molecular Weight: 397.9. US Biological Life Sciences.
Worldwide
Azeliragon
Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). Uses: A potent and orally active rage inhibitor. Synonyms: TTP488; PF04494700; TTP 488; PF0 4494700; TTP-488; PF-044947003-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-1-propanamine. Grades: ≥98%. CAS No. 603148-36-3. Molecular formula: C32H38ClN3O2. Mole weight: 532.124.
Azelnidipine
Azelnidipine is a dihydropyridine calcium channel blocker with antihypertensice activity. Azelnidipine is used for treating ischemic heart disease and cardiac remodeling after myocardial infarction. Studies show that Azelnidipine ttreatment can reduce the risk of hyperglycemia induced metabolic disorders. Group: Biochemicals. Alternative Names: (±)-2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) Ester; Azelnidipine; CS 905; Calblock 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-isopropyl (±)-2-Amino-1,4-dihydro-6-methyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate. Grades: Highly Purified. CAS No. 123524-52-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Azelnidipine
Azelnidipine (CS 905) is a dihydropyridine calcium channel blocker that is effective orally. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS 905. CAS No. 123524-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0023.
Azelnidipine
Azelnidipine is a dihydropyridine calcium channel blocker. Synonyms: CS 905; CS-905; CS905; CCRIS 8650; CCRIS8650; CCRIS-8650; Azelnidipine; brand name CalBlock. UR-12592; UR 12592; UR12592. Grades: >98%. CAS No. 123524-52-7. Molecular formula: C33H34N4O6. Mole weight: 582.65.
Azemiglitazone
Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier ( MPC ), which inhibits Alzheimers disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602. CAS No. 1133819-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108022.
Azemiglitazone potassium
Azemiglitazone potassium (MSDC-0602K), a PPARγ -sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC 50 of 18.25 μM [1]. Azemiglitazone potassium modulates the mitochondrial pyruvate carrier (MPC). Azemiglitazone potassium can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance [2]. Azemiglitazone potassium, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602K. CAS No. 1314533-27-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108022A.
Azenosertib
Azenosertib (ZN-c3) is a selective, orally active inhibitor for Wee1 inhibitor ( IC 50 =3.9 nM). Azenosertib exhibits antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZN-c3. CAS No. 2376146-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132295.
Azepan-2-one
Azepan-2-one is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 105-60-2. Pack Sizes: 25 g; 50 g. Product ID: HY-W010542.
Azepan-4-ol
Azepan-4-ol. Group: Biochemicals. Alternative Names: Hexahydro-1H-azepin-4-ol. Grades: Highly Purified. CAS No. 39888-51-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Azepan-4-ol ≥96% (HPLC)
Azepan-4-ol ≥96% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Azepan-4-one hydrochloride
Azepan-4-one hydrochloride. Group: Biochemicals. Alternative Names: Hexahydro-4H-azepin-4-one hydrochloride. Grades: Highly Purified. CAS No. 50492-22-3. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C6H12ClNO. US Biological Life Sciences.
Worldwide
Azepan-4-one, Hydrochloride
Azepan-4-one, Hydrochloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Azepexole hydrochloride is an agonist of α2-adrenergic receptors (α2-ARs). It induces sedation and reduces motor activity in mice and causes concentration-dependent inhibition of peristaltic contractions. Synonyms: 4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1); 6-ethyl-4H,5H,6H,7H,8H-[1,3]oxazolo[4,5-d]azepin-2-amine hydrochloride. Grades: >98.0%. CAS No. 147663-20-5. Molecular formula: C9H16ClN3O. Mole weight: 217.7.
Employed in a high yielding palladium-catalyzed cross-coupling with aryl bromides. Also used in a Ullmann type coupling with iodonitroflourenes. Group: Organic phosphine compounds. Alternative Names: 1,3-Propylenimine; Azetidin; Trimethylenimine; trimethyleneimine; Azetidine; Azacyclobutane. CAS No. 503-29-7. Molecular formula: C3H7N. Mole weight: 57.09. Appearance: Clear, colorless liquid. Purity: 0.98. IUPACName: azetidine. Canonical SMILES: C1CNC1. Density: 0.847. ECNumber: 207-963-8. Catalog: ACM503297-1.
Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Azetidine-2-carboxamide
Azetidine-2-carboxamide. Group: Biochemicals. Alternative Names: Azetidine-2-carboxylic acid amide. Grades: Highly Purified. CAS No. 130973-78-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences.
Worldwide
Azetidine-2-carboxamide ≥97% (HPLC)
Azetidine-2-carboxamide ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Azetidine-2-carboxylic acid
Azetidine-2-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 2517-4-6. Pack Sizes: 10g, 25g. Molecular Formula: C4H7NO2. US Biological Life Sciences.
Worldwide
Azetidine-2-carboxylic acid
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2517-4-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-75308.
Azetidine-3-carboxylic acid
Azetidine-3-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 36476-78-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H7NO2. US Biological Life Sciences.
Worldwide
Azetidine-3-carboxylic acid
Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 36476-78-5. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0530.
Azetidine-3-carboxylic acid, > ≥97%
Azetidine-3-carboxylic acid, > ≥97%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Azetidine-3-carboxylic acid hydrochloride
Heterocyclic Organic Compound. Alternative Names: 3-Azetidinecarboxylic acid, hydrochloride (1:1). CAS No. 102624-96-4. Molecular formula: C4H7NO2.ClH. Density: g/cm³. Catalog: ACM102624964.
Azetidine hydrochloride
Azetidine hydrochloride. Group: Biochemicals. Alternative Names: 1,3-Propylenimine hydrochloride; Azacyclobutane hydrochloride; Tetrahydro-azete hydrochloride. Grades: Highly Purified. CAS No. 36520-39-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C3H8ClN. US Biological Life Sciences.
Worldwide
Azetidine hydrochloride
Azetidine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Trimethyleneimine hydrochloride. CAS No. 36520-39-5. Pack Sizes: 5 g; 10 g. Product ID: HY-W010628.
Azetukalner
KCNQ2/3 activator-1 is an activator of Kv7.2/Kv7.3 ( KCNQ2/3 ) potassium channel. KCNQ2/3 activator-1 has the potential in relieving pain (the main problem from medical treatment) (extracted from patent WO2021113757A1, compound A) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XEN1101. CAS No. 1009344-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139791.
AZ-GHS-22
AZ-GHS-22 is an orally-available Ghrelin receptor (GHS-R1a) inverse agonist (IC50 = 0.77 nM) with very low CNS exposure. Synonyms: AZ-GHS-22; AZ GHS-22; AZ-GHS 22; AZ GHS 22; AZGHS22; 2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide. Grades: 98%. CAS No. 1143020-91-0. Molecular formula: C27H33ClN6O5S2. Mole weight: 621.17.
This formulation is Doxorubicin Liposome (PEGylated) with the azide group, which can react with an dibenzocyclooctyne (DBCO) by click chemistry. The conjugation chemistry is based on the reaction of the azide reagent with an DBCO linker to form a stable triazole. DBCO moiety can be on the antibody and azide moiety can be on liposome and vice versa. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Azide-PEG2-Ms is a polyethylene glycol (PEG)-based PROTAC linker. Azide-PEG2-Ms can be used in the synthesis of a series of PROTACs. Grades: 98%. CAS No. 176520-23-3. Molecular formula: C5H11N3O4S. Mole weight: 209.22.
Azide-PEG4-aminoallyl-dUTP is a dUTP analog that can be incorporated into DNA/cDNA by PCR with Taq polymerase. It is a reagent for DNA labeling with click chemistry. Synonyms: 5-(15-Azido-4,7,10,13-tetraoxa-pentadecanoyl-aminoallyl)-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C23H39N6O19P3 (free acid). Mole weight: 796.51 (free acid).
Azido 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-galactopyranosyl
An intermediate useful in carbohydrate chemistry. Synonyms: Azido 2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl 3,4,6-Triacetate. CAS No. 39541-20-3. Molecular formula: C14H20N4O8. Mole weight: 372.33.
Azidoacetic Acid
Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Azidoacetic acid. CAS No. 18523-48-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-151719.
Azidobenzene solution (CAS# 622-37-7) is a useful research chemical. Synonyms: azidobenzene. CAS No. 622-37-7. Molecular formula: C6H5N3. Mole weight: 119.12.
A derivative of S. Group: Biochemicals. Alternative Names: (2S,3R,4E)-2-Azido-4-octadecene-1,3-diol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibits lymphocyte egress from lymphoid tissues by down-regulating sphingosine-1 phosphate receptor (S1PR). Phosphorylation of FTY270 by sphingosine kinase can cause S1P1R internalization, which sequesters lymphocytes in lymph nodes, preventing them from taking part in an autoimmune response. It is a first-in-class orally bioavailable compound that has shown efficacy in advanced clinical trials for the treatment of multiple sclerosis (MS). Synonyms: azido-FTY720; 881914-35-8; 2-Amino-2-[2-(3-azido-4-octylphenyl)ethyl]-1,3-propanediol; 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol; 1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]-; AKOS040755896; HY-134976; CS-0168486. Grades: ≥98%. CAS No. 881914-35-8. Molecular formula: C19H32N4O2. Mole weight: 348.5.
Azidomethyl phenyl sulfide
Azidomethyl phenyl sulfide (CAS# 77422-70-9 ) is a useful research chemical. Synonyms: azidomethylsulfanylbenzene. Grades: > 97.0 % (LC). CAS No. 77422-70-9. Molecular formula: C7H7N3S. Mole weight: 165.22.
Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2. Grades: >97%. CAS No. 912849-73-1. Molecular formula: C22H46N4O10. Mole weight: 526.62.