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| Product | Description | |
|---|---|---|
| Arohynapene B | Arohynapene B is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. It has no antibacterial activity. Synonyms: 5-(2-Hydroxymethyl-6,8-dimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-2-(hydroxymethyl)-6,8-dimethyl-1-naphthalenyl)-. CAS No. 154445-09-7. Molecular formula: C18H22O3. Mole weight: 286.36. |  |
| Arohynapene D | Arohynapene D is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. The MIC that Arohynapene D shows toxicity to BHK-21 cells is 1.0 X 10-6 mol/L. Molecular formula: C11H14O3. Mole weight: 194.23. | |
| Aromadendrene | Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Aromadendrene. CAS No. 489-39-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8411. |  |
| Aromadendrin | Aromadendrin, which usually comes from the bark of Eucalyptus calophylla, exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells. Aromadendrin may represent a potential therapeutic candidate for the management of type 2 DM. Uses: Anti-inflammatory/antioxidant/anti-diabetic. Synonyms: 3,5,7,4'-Tetrahydroxyflavanone; Dihydrokaempferol; aromadedrin; (2R)-2,3-Dihydro-3β,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2R,3R)-2,3-Dihydro-2-(4-hydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Katuranin. Grade: >98%. CAS No. 480-20-6. Molecular formula: C15H12O6. Mole weight: 288.3. | |
| Aromadendrin 7-O-rhamnoside | Aromadendrin 7-O-rhamnoside, a flavonoid compound present in numerous plant species, exhibits considerable efficacy as an antioxidant and anti-inflammatory agent, and is considered to have therapeutic potential in diverse pathological conditions including cancer and diabetes. Its efficacy can be attributed to its natural composition making it a plausible resource for discovery of novel pharmacological targets in the nutraceutical and pharmaceutical sectors. Synonyms: (2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one. Grade: 97.5%. CAS No. 69135-41-7. Molecular formula: C21H22O10. Mole weight: 434.39. | |
| aromatase | A cytochrome P-450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17β-estradiol, respectively. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: CYP19A1 (gene name); estrogen synthetase (incorrect). Enzyme Commission Number: EC 1.14.14.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0911; aromatase; EC 1.14.14.14; CYP19A1 (gene name); estrogen synthetase (incorrect). Cat No: EXWM-0911. |  |
| Aromatase-IN-2 | Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430. | |
| aromatic-amino-acid-glyoxylate transaminase | Phenylalanine, kynurenine, tyrosine and histidine can act as amino donors; glyoxylate, pyruvate and hydroxypyruvate can act as amino acceptors. Group: Enzymes. Enzyme Commission Number: EC 2.6.1.60. CAS No. 67185-76-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2902; aromatic-amino-acid-glyoxylate transaminase; EC 2.6.1.60; 67185-76-6. Cat No: EXWM-2902. | |
| aromatic-amino-acid transaminase | A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC 2.6.1.1 aspartate transaminase. Group: Enzymes. Synonyms: aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Enzyme Commission Number: EC 2.6.1.57. CAS No. 37332-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2898; aromatic-amino-acid transaminase; EC 2.6.1.57; 37332-38-0; aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Cat No: EXWM-2898. | |
| Aromatic hydrocarbons, C6-10, C8-rich | Aromatic hydrocarbons, C6-10, C8-rich. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aromatic hydrocarbons, C6-10, C8-rich;Aromatic hydrocarbons, C6-10, C8-rich Light Oil Redistillate, low boiling. Product Category: Heterocyclic Organic Compound. CAS No. 90989-41-6. Product ID: ACM90989416. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Aromatic Hydrocarbon Standard | certified reference material, 1000 ?g/mL in methylene chloride. Group: Certified reference materials (crms). |  |
| aromatic-hydroxylamine O-acetyltransferase | Transfers the N-acetyl group of some aromatic acethydroxamates to the O-position of some aromatic hydroxylamines. Group: Enzymes. Synonyms: aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Enzyme Commission Number: EC 2.3.1.56. CAS No. 52660-15-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2235; aromatic-hydroxylamine O-acetyltransferase; EC 2.3.1.56; 52660-15-8; aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Cat No: EXWM-2235. | |
| aromatic-L-amino-acid decarboxylase | A pyridoxal-phosphate protein. The enzyme also acts on some other aromatic L-amino acids, including L-tryptophan, L-tyrosine and L-phenylalanine. Group: Enzymes. Synonyms: DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Enzyme Commission Number: EC 4.1.1.28. CAS No. 9042-64-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4771; aromatic-L-amino-acid decarboxylase; EC 4.1.1.28; 9042-64-2; DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Cat No: EXWM-4771. | |
| Aromatics Content Standard | ASTM D 5580 (26.78%). Group: Certified reference materials (crms). | |
| Aromatic solvents | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| Aronia P.E. 4:1 | Aronia P.E. 4:1. |  CA, FL & NJ |
| Aroplatin | Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. The liposomal encapsulation improves the bioavailability of NDDP and reduces its toxicity profile. CAS No. 114488-24-3. Molecular formula: C26H52N2O4Pt. Mole weight: 651.79. | |
| Arotinoid | Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors ( RARs ) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED 50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6298; Arotinoid ethyl ester. CAS No. 71441-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106735. | |
| Arotinolol | Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker [1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125 I-ICYP to 5HT 1B -serotonergic receptor sites [2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68377-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122537A. | |
| Arotinolol | Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 68377-92-4. Pack Sizes: 100mg, 1g. Molecular Formula: C15H21N3O2S3. US Biological Life Sciences. |  Worldwide |
| Arotinolol | Arotinolol is a medication used primarily for the treatment of hypertension and certain types of arrhythmias. Arotinolol is a non-selective beta-adrenergic receptor antagonist (beta-blocker) that blocks both beta-1 and beta-2 receptors. This action reduces the effects of adrenaline and noradrenaline, leading to a decrease in heart rate and blood pressure. In addition to its beta-blocking properties, arotinolol also exhibits alpha-1 adrenergic receptor antagonism. This action leads to vasodilation and further reduction in blood pressure. Arotinolol is used to treat high blood pressure, helping to prevent complications such as stroke, heart attack, and kidney problems. It can be used to manage certain types of cardiac arrhythmias (irregular heartbeats). Arotinolol may be used to alleviate symptoms of angina, a condition characterized by chest pain due to reduced blood flow to the heart. Synonyms: 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-; 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-, (±)-; 5-[2-[[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-2-thiophenecarboxamide; (±)-Arotinolol; 2-(3-tert-Butylamino-2-hydroxypropylthio)-4-(5-carbamoyl-2-thienyl)thiazole; NSC 317940. Grade: ≥95%. CAS No. 68377-92-4. Molecular formula: C15H21N3O2S3. Mole weight: 371.54. | |
| Arotinolol hydrochloride | Arotinolol hydrochloride. Synonyms: 5-[2-[(2S)-3-(tert-butylamino)-2-hydroxypropyl]sulfanyl-1,3-thiazol-4-yl]thiophene-2-carboxamide; hydrochloride; UNII-FX47K0HTP6; FX47K0HTP6; 101540-26-5; SCHEMBL348621. Grade: 95%. CAS No. 101540-26-5. Molecular formula: C15H21N3O2S3?ClH. Mole weight: 408.009. | |
| Arotinolol hydrochloride | Arotinolol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[2-[[3-(tert-Butylamino)-2-hydroxypropyl]thio]thiazol-4-yl]thiophene-2-carboxamide Hydrochloridel. Product Category: Thiophenes. CAS No. 68377-91-3. Molecular formula: C15H22ClN3O2S3. Mole weight: 407.99. Purity: 0.98. Product ID: ACM68377913. Alfa Chemistry ISO 9001:2015 Certified. | |
| Arotinolol impurity 8 | Arotinolol impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1682660-95-2. Molecular formula: C8H6N2O2S2. Mole weight: 226.27. Catalog: APB1682660952. | |
| ARP 100 | ARP 100. Group: Biochemicals. Grades: Purified. CAS No. 704888-90-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| ARP 100 | ARP 100 has been found to be a selective inhibitor of MMP-2 and could show anti-invasive properties in HT1080 fibrosarcoma cells at some extent. Synonyms: ARP100; ARP-100; ARP 100; 2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide. Grade: ≥98% by HPLC. CAS No. 704888-90-4. Molecular formula: C17H20N2O5S. Mole weight: 364.42. | |
| ARP-100 | ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1? pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 ?M), MMP-3 (4.5 ?M), MMP-7 (>50 ?M), and MMP-9 (0.2 ?M)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 704888-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103444. | |
| ARP 101 | ARP 101. Group: Biochemicals. Grades: Purified. CAS No. 849773-63-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| ARP 101 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| ARP 101 | ARP 101 is a Selective MMP-2 inhibitor with IC50 value of 0.81 nM. It displays nearly 600-fold selectivity over MMP-1 (IC50 value 486 nM). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis and so on. Synonyms: ARP-101; ARP 101; ARP101; (2R)-N-hydroxy-3-methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanamide. Grade: 98%. CAS No. 849773-63-3. Molecular formula: C20H26N2O5S. Mole weight: 406.50. | |
| Arphamenine a | Arphamenine a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Arphamenine A, Arphamenine A hydrochloride, C16H24N4O3.HCl, CID5487157, LS-31060, 5-amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid, 5-Amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid hydrochloride, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-, monohydrochloride, (S-(R*,S*))-, 85713-14-0, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-,monohydrochloride, (S-(R*,S*))-. Product Category: Heterocyclic Organic Compound. CAS No. 85713-14-0. Molecular formula: C32H50N8O10S. Mole weight: 356.847700 [g/mol]. Purity: 0.96. IUPACName: (2R,5S)-5-amino-2-benzyl-8-(diaminomethylideneamino)-4-oxooctanoic acid hydrochloride. Product ID: ACM85713140. Alfa Chemistry ISO 9001:2015 Certified. | |
| Arphamenine A | Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grade: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39. | |
| Arphamenine A hemisulfate | Arphamenine A hemisulfate is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Arphamenine A sulfate; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-, sulfate (2:1); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, sulfate, [S-(R*,S*)]-; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid sulfate (2:1). Grade: >98%. CAS No. 144110-37-2. Molecular formula: C16H24N4O3.1/2H2O4S. Mole weight: 369.43. | |
| Arphamenine A hydrochloride | Arphamenine A hydrochloride is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, monohydrochloride, [S-(R*,S*)]-; Arphamenine A monohydrochloride; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid hydrochloride (1:1); Benzenepropanoic acid, α-[(3S)-3-amino-6-[(diaminomethylene)amino]-2-oxohexyl]-, (αR)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 85713-14-0. Molecular formula: C16H24N4O3.HCl. Mole weight: 356.85. | |
| Arphamenine B | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grade: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39. | |
| Arphamenine B hemisulfate | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grade: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43. | |
| Arphamenine B hydrochloride | Arphamenine B is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-; Arphamenine B monohydrochloride; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, monohydrochloride; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid monohydrochloride. Grade: ≥95%. CAS No. 88465-81-0. Molecular formula: C16H24N4O4.HCl. Mole weight: 372.85. | |
| Arprinocid | Arprinocid is a coccidiostat used in veterinary medicine. Uses: Coccidiostats. Synonyms: Arpocox; Arprinocide; MK302; MK-302; MK 302; 9-(2-Chloro-6-fluorobenzyl)-9H-purin-6-amine; 6-Amino-9-(2-chloro-6-fluorobenzyl)purine. CAS No. 55779-18-5. Molecular formula: C12H9ClFN5. Mole weight: 277.69. | |
| Arprinocid | A Coccidiostat used in veterinary medicine. Group: Biochemicals. Alternative Names: 9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purin-6-amine; 6-Amino-9-(2-chloro-6-fluorobenzyl)purine; Arpocox; MK 302. Grades: Highly Purified. CAS No. 55779-18-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| ARQ 069 | ARQ 069 is an analogue of ARQ 523 and inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases with IC50s of 0.84 and 1.23 μM, respectively. It inhibits FGFR1/FGFR2 autophosphorylation through a non-ATP competitive dependent mechanism with IC50s of 2.8 and 1.9 μM, respectively. Synonyms: Benzo[h]quinazolin-2-amine, 5,6-dihydro-6-phenyl-, (6S)-; 3RH. Grade: ≥95%. CAS No. 1314021-57-2. Molecular formula: C18H15N3. Mole weight: 273.33. | |
| ARQ-087 | ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Synonyms: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. Grade: ≥98%. CAS No. 1234356-69-4. Molecular formula: C29H29FN4O. Mole weight: 468.576. | |
| ARQ-092 | ARQ-092, also called as Miransertib, is an oral activie, potent and selective AKT inhibitor with IC50=5.0 nM against AKT1, 4.5 nM against AKT2 and 16 nM against AKT3. ARQ-092 inhibits the PI3K/AKT signaling pathway due to inhibition of the activity of AKT in a non-ATP competitive manner. This may lead to the reduction in tumor cell proliferation and the induction of tumor cell apoptosis. Synonyms: 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine; ARQ092; ARQ-092; ARQ 092; Miransertib. Grade: >98%. CAS No. 1313881-70-7. Molecular formula: C27H24N6. Mole weight: 432.53. | |
| ARQ 531 | ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity. ARQ 531 is a reversible non-covalent inhibitor of Bruton's Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases. In GCB-DLBCL cell lines (SUDHL-4 and DOHH-2), ARQ 531 potently suppressed expression of anti-apoptotic c-Myc and BCL6 oncoproteins in a dose-dependent fashion, and concomitantly induced apoptotic cleavage of PARP protein. Synonyms: ARQ-531. Grade: ≥98%. CAS No. 2095393-15-8. Molecular formula: C25H23ClN4O4. Mole weight: 478.93. | |
| ARQ 531 | ARQ 531 Inhibitor. Uses: Scientific use. Product Category: T14323. CAS No. 2095393-15-8. |  |
| ARQ-621 | ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies. Synonyms: NSC-771644; N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluorobenzamide; (R)-N-(3-Aminopropyl)-3-chloro-N-(1-(7-chloro-4-oxo-3-(phenylamino)-3,4-dihydroquinazolin-2-yl)but-3-yn-1-yl)-2-fluorobenzamide; Benzamide, N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-. Grade: ≥95%. CAS No. 1095253-39-6. Molecular formula: C28H24Cl2FN5O2. Mole weight: 552.43. | |
| ARQ 736 | ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. Synonyms: ARQ 736; ARQ736; ARQ-736. CAS No. 1228237-47-5. Molecular formula: C25H25N8Na2O8PS. Mole weight: 630.569. | |
| ARQ 736 disodium salt | This active molecular is a Proto oncogene protein b raf and Vascular endothelial growth factor A inhibitor originated by ArQule. ARQ 736 is effective in killing cancer cell lines that harboring at least one mutated b raf allele. The b raf protein is really a very important signaling molecule in the MAPK (mitogen activated protein kinase) signaling pathway and it relates to pathogenesis of variety kinds of cancer. In Mar 2014, Phase-I for Solid tumours (late-stage disease) was discontinued in USA. Uses: Solid tumours. Synonyms: ARQ 736 disodium salt; ARQ736 disodium salt; ARQ-736 disodium salt; sodium (R)-(3-(5-(2-((1-((1-methyl-1H-pyrazol-3-yl)sulfonyl)piperidin-3-yl)amino)pyrimidin-4-yl)imidazo[2,1-b]oxazol-6-yl)phenoxy)methyl phosphate; 1228237-47-5 free acid. Grade: 98%. CAS No. 1228237-57-7. Molecular formula: C25H25N8Na2O8PS. Mole weight: 674.54. | |
| AR-R 17779 hydrochloride | AR-R17779 has been found to be a selective alpha7 nicotinic agonist and could probably reduce blood pressure and serum lipid levels. Synonyms: AR-R 17779 hydrochloride; AR-R-17779 hydrochloride; AR-R17779 hydrochloride; ARR17779 hydrochloride; (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidine]-2'-one hydrochloride. Grade: ≥98% by HPLC. CAS No. 178419-42-6. Molecular formula: C9H14N2O2.HCl. Mole weight: 218.68. | |
| AR-R17779 hydrochloride | AR-R17779 hydrochloride is a potent and selective full agonist of nAChR , with K i s of 92 and 16000 nM for α7 and α4β2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178419-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135483A. | |
| AR-R17779 Hydrochloride | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Arrow Root Powder (Maranta arundinacea) | Arrow Root Powder (Maranta arundinacea). | CA, FL & NJ |
| ARRY-380 | ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR. Synonyms: ARRY-380; ARRY 380; ARRY380. Grade: >98%. CAS No. 937265-83-3. Molecular formula: C29H27N7O4S. Mole weight: 569.63. | |
| ARRY-380 analog | ARRY-380 analog, an inhibitor of EGFR (ErbB1) , is extracted from patent WO2015153959A2, compound 249 [1]. ARRY-380 is a potent, selective, ATP-competitive, orally active inhibitor of HER2 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937265-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10531. | |
| ARRY-382 | ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC 50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1313407-95-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136362. | |
| ARRY-382 | ARRY-382 is a potent and selective inhibitor of the CSF1R with IC50 of 9 nM. ARRY-382 can be combined with Pembrolizumab for the treatment of advanced solid tumors. Synonyms: c-Fms-IN-12; ARRY382; ARRY 382. CAS No. 1313407-95-2. Molecular formula: C32H36N8O2. Mole weight: 564.68. | |
| ARRY 403 | ARRY-403 is an orally available Glucokinase stimulants originated by Array BioPharma. ARRY-403 activates human glucokinase in vitro with EC50 of 79 nM at 5 mM glucose and Vmax = 134% compared to the no activator control. It exhibits good in vitro drug-like properties and selectivity against broad panels of receptors and enzymes. But,treatment for Type 2 diabetes mellitus was discontinued. Uses: Type 2 diabetes mellitus. Synonyms: ARRY-403; ARRY-403; ARRY-403; AMG-151; AMG 151; AMG151; (1S)-1-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol. Grade: 98%. CAS No. 1304015-76-6. Molecular formula: C20H18N6O3S2. Mole weight: 454.53. | |
| ARRY 520 hydrochloride | ARRY 520 hydrochloride is a kinesin spindle protein (Ksp) inhibitor with potential antineoplastic activity. Synonyms: Filanesib hydrochloride; (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide Hydrochloride; 1,3,4-Thiadiazole-3(2H)-carboxamide, 2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-, hydrochloride (1:1), (2S)-; ARRY-520 hydrochloride. Grade: 95%. CAS No. 1385020-40-5. Molecular formula: C20H23ClF2N4O2S. Mole weight: 456.94. | |
| ARRY-520 R enantiomer | ARRY-520 R enantiomer is the R form of ARRY-520, which is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor. ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Synonyms: ARRY-520 R enantiomer; ARRY 520 R enantiomer; ARRY520 R enantiomer; 1,3,4-Thiadiazole-3(2H)-carboxamide, 2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-, (2R)-. Grade: >98%. CAS No. 885060-08-2. Molecular formula: C20H22F2N4O2S. Mole weight: 420.48. | |
| ARRY 520 trifluoroacetate | ARRY 520 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 885060-09-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ARRY-797 | ARRY-797 is a potent and selective p38α inhibitor that inhibits LPS-induced IL-6. Synonyms: p38alpha inhibitor 1; p38α inhibitor 1; 5-(2,4-Difluorophenoxy)-N-(2-(dimethylamino)ethyl)-1-isobutyl-1H-indazole-6-carboxamide; 1H-Indazole-6-carboxamide, 5-(2,4-difluorophenoxy)-N-[2-(dimethylamino)ethyl]-1-(2-methylpropyl)-; ARRY 797; ARRY797. Grade: ≥95%. CAS No. 1036404-17-7. Molecular formula: C22H26F2N4O2. Mole weight: 416.46. | |
| ARS-1323 | ARS-1323 is an inhibitor of mutant K-ras G12C. Synonyms: ARS-1323; ARS 1323; ARS1323; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one. CAS No. 1698024-73-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ARS-1620 | ARS-1620 is a potent and selective KRAS-G12C inhibitor. ARS-1620 achieves rapid and sustained in vivo target occupancy to induce tumor regression. Synonyms: ARS-1620; ARS 1620; ARS1620; BCP29125; BCP 29125; BCP-29125; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one sulfane. CAS No. 1698055-85-4. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ARS-1620 | ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics. Uses: Scientific research. Group: Signaling pathways. CAS No. 1698055-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00418. | |
| ARS-1630 | ARS-1630 is the R-enantiomer of ARS-1620. It is an inhibitor of mutant K-ras G12C. Synonyms: ARS-1630; ARS 1630; ARS1630; (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one. CAS No. 1698055-86-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84. | |
| ARS-853 | ARS-853 is a selective, allele-specific inhibitor of KRAS, which blocks KRAS signaling and suppresses tumor growth (IC50 = 2.5 μM). Synonyms: ARS-853; ARS853; ARS 853; SCHEMBL16117872; AKOS032944976; CS-6065; CS 6065; CS6065; 1-[3-[4-[2-[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)anilino]acetyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one. Grade: 99.02 %. CAS No. 1629268-00-3. Molecular formula: C22H29ClN4O3. Mole weight: 432.94. | |
| Arsanilic Acid USP | Arsanilic Acid USP. CAS No. 98-50-0. Molecular formula: C6H8AsNO3. |  |
| Arsenate(1-),hexafluoro-,rubidium(9ci) | Arsenate(1-),hexafluoro-,rubidium(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RUBIDIUM HEXAFLUOROARSENATE;RUBIDIUM HEXAFLUOROARSENATE (V);RUBIDIUM HEXAFLUOROARSENATE (V), 98% (METALS BASIS);Rubidium hexafluoroarsenate 98%;Rubidiumhexafluoroarsenate98%. Product Category: Heterocyclic Organic Compound. CAS No. 43023-95-6. Molecular formula: AsF6.Rb. Mole weight: 274.38. Purity: 0.96. IUPACName: hexafluoroarsenic(1-); rubidium(1+). Canonical SMILES: F[As-](F)(F)(F)(F)F.[Rb+]. Product ID: ACM43023956. Alfa Chemistry ISO 9001:2015 Certified. Categories: Rubidium hexafluoroarsenate(V). | |
| arsenate-mycothiol transferase | Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate. The product arseno-mycothiol is reduced by EC 1.20.4.3 (mycoredoxin) to arsenite and mycothiol-mycoredoxin disulfide. Finally, a second mycothiol recycles mycoredoxin and forms mycothione. Group: Enzymes. Synonyms: ArsC1; ArsC2; mycothiol:arsenate transferase. Enzyme Commission Number: EC 2.8.4.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3428; arsenate-mycothiol transferase; EC 2.8.4.2; ArsC1; ArsC2; mycothiol:arsenate transferase. Cat No: EXWM-3428. | |
| arsenate reductase (azurin) | Contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster. Isolated from β-proteobacteria. Also uses a c-type cytochrome or O2 as acceptors. Group: Enzymes. Synonyms: arsenite oxidase (ambiguous). Enzyme Commission Number: EC 1.20.9.1. CAS No. 146907-46-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1244; arsenate reductase (azurin); EC 1.20.9.1; 146907-46-2; arsenite oxidase (ambiguous). Cat No: EXWM-1244. | |
| arsenate reductase (cytochrome c) | A molybdoprotein containing iron-sulfur clusters. Isolated from α-proteobacteria. Unlike EC 1.20.9.1, arsenate reductase (azurin), it does not use azurin as acceptor. Group: Enzymes. Synonyms: arsenite oxidase (ambiguous). Enzyme Commission Number: EC 1.20.2.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1239; arsenate reductase (cytochrome c); EC 1.20.2.1; arsenite oxidase (ambiguous). Cat No: EXWM-1239. | |
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