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| Product | Description | |
|---|---|---|
| Arisostatin B | Arisostatin B is a Tetrocarcin antibiotic produced by Micromonospora sp. TP-A0316. It has anti-Gram-positive bacteria activity, anti-Bacillus subtilis and anti-tumor activity. CAS No. 271574-42-6. Molecular formula: C69H102N2O22. Mole weight: 1311.54. |  |
| Aristeromycin | Aristeromycin is a nucleoside antibiotic produced by Streptomyces citricolor. It has a minimum inhibitory concentration of 5 mg/mL against Xanthomonas oryzae and Pear. Synonyms: Cycloadenosine; (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol. CAS No. 19186-33-5. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| ARISTOLACTAM-AII | Aristolactam AII is an alkaloid compound found in the herbs of Aristolochia debilis Sieb. et Zucc. Aristolactam AII exhibits the activities of antiinflammatory and antimicrobial. Aristolactam AII also has platelet aggregation inhibitory activity. Uses: Antiinflammatory, antimicrobial. Synonyms: 2-Hydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one; 3-Hydroxy-4-methoxy-10-aminophenanthrene-1-carboxylic acid 1,10-lactam. Grade: >98%. CAS No. 53948-07-5. Molecular formula: C16H11NO3. Mole weight: 265.3. | |
| Aristolactam FI | Aristolactam FI is a natural alkaloid found in the roots of Piper longum, it shows platelet aggregation inhibitory activity and may be potential cancer chemotherapeutic and chemopreventive agents. Uses: Anti-cancer. Synonyms: 1-Hydroxy-2-methoxydibenz[cd,f]indol-4(5H)-one; Piperolactam A. Grade: >95%. CAS No. 112501-42-5. Molecular formula: C16H11NO3. Mole weight: 265.3. | |
| Aristolactam I | Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage.Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Methoxy-6-aminophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid 5,6-lactam. Product Category: Inhibitors. Appearance: Powder. CAS No. 13395-02-3. Molecular formula: C17H11NO4. Mole weight: 293.27. Purity: 0.98. IUPACName: 14-Methoxy-3,5-dioxa-10-azapentacyclo[9.7.1.02,6.08,19.013,18]nonadeca-1(18),2(6),7,11(19),12,14,16-heptaen-9-one. Canonical SMILES: COC1=CC=CC2=C3C4=C(C=C21)NC(=O)C4=CC5=C3OCO5. Density: 1.49 g/ml. Product ID: ACM13395023. Alfa Chemistry ISO 9001:2015 Certified. |  |
| aristolochene synthase | The initial internal cyclization produces the monocyclic intermediate germacrene A; further cyclization and methyl transfer converts the intermediate into aristolochene. While in some species germacrene A remains as an enzyme-bound intermediate, it has been shown to be a minor product of the reaction in Penicillium roqueforti (see also EC 4.2.3.23, germacrene-A synthase). The enzyme from Penicillium roqueforti requires Mg2+. Mn2+ can partially substitute, at low concentrations. Aristolochene is the likely parent compound for a number of sesquiterpenes produced by filamentous fungi. Group: Enzymes. Synonyms: sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Enzyme Commission Number: EC 4.2.3.9. CAS No. 94185-89-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5253; aristolochene synthase; EC 4.2.3.9; 94185-89-4; sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Cat No: EXWM-5253. |  |
| Aristolochic acid | 5mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C17H11NO7. CAS No. 313-67-7. Prepack ID 17348594-5mg. Molecular Weight 341.2717. See USA prepack pricing. |  |
| Aristolochic Acid (8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic Acid, Aristolochine) | Aristolochic acids occur in Aristolochiaceae and in butterflies feeding on these plants. Group: Biochemicals. Alternative Names: 8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic Acid; Aristolochine. Grades: Highly Purified. CAS No. 313-67-7. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Aristolochic acid A | Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Aristolochic acid I; TR 1736. CAS No. 313-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0510. |  |
| Aristolochic acid A | Aristolochic acid A. Group: Biochemicals. Alternative Names: 8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochine; Aristolochia A. Grades: Highly Purified. CAS No. 313-67-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H11NO7. US Biological Life Sciences. | Worldwide |
| Aristolochic acid b | Aristolochic acid b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ARISTOLOCHIC ACID II;ARISTOLOCHIC ACID A, 7-HYDROXY-;ARISTOLOCHIC ACID B;3,4-(methylenedioxy)-10-nitrophenanthrene-1-carboxylicacid;4-d)-1,3-dioxole-5-carboxylicacid,6-nitro-phenanthro(;6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;?3,4-(Methyle. Appearance: white crystalline powder. CAS No. 475-80-9. Molecular formula: C16H9NO6. Mole weight: 311.25. Purity: 97%+. IUPACName: 6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylicacid. Canonical SMILES: C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-]. Density: 1.61 g/cm³. ECNumber: 207-499-6. Product ID: ACM475809. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aristolochic acid B | Aristolochic acid B. Group: Biochemicals. Alternative Names: 6-Nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid II; 3,4-(Methylenedioxy)-10-nitrophenanthrene-1-carboxylic acid. Grades: Highly Purified. CAS No. 475-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H9NO6. US Biological Life Sciences. | Worldwide |
| Aristolochic acid C | Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A 2 ( PLA2 ) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis [1]. Uses: Scientific research. Group: Natural products. CAS No. 4849-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1450. | |
| Aristolochic acid C | Aristolochic acid C. Group: Biochemicals. Alternative Names: 10-Hydroxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid IIIa. Grades: Highly Purified. CAS No. 4849-90-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H9NO7. US Biological Life Sciences. | Worldwide |
| Aristolochic acid D | Aristolochic acid D. Group: Biochemicals. Alternative Names: 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid IVa. Grades: Highly Purified. CAS No. 17413-38-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H11NO8. US Biological Life Sciences. | Worldwide |
| Aristolochic acid I | powder. Group: Fluorescence/luminescence spectroscopyeuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: TR 1736, Tardolyt,8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, Aristolochia A, Aristolochic acid 1, Aristolochic acid, Aristolochic acid A, Aristolochic acid I, NSC 11926, NSC 50413, 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid. |  |
| Aristolochic acid II | Aristolochic acid II. Group: Biochemicals. CAS No. 475-80-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aristolochic acid I sodium salt | powder, ?97%. Group: Fluorescence/luminescence spectroscopy. | |
| Aristolochic acid sodium salt | Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate. CAS No. 10190-99-5. Pack Sizes: 1 mg; 10 mg. Product ID: HY-N0510A. | |
| Aristolochic acid Va | Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants [1]. Uses: Scientific research. Group: Natural products. CAS No. 108779-46-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11445. | |
| Aristololactam | Aristololactam. Group: Biochemicals. Alternative Names: Aristolactam. Grades: Plant Grade. CAS No. 13395-02-3. Pack Sizes: 10mg. Molecular Formula: C17H11NO4, Molecular Weight: 293.274. US Biological Life Sciences. | Worldwide |
| Aristololactam BII | Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells. Uses: Anti-syncytium. Synonyms: Cepharanone B. Grade: >97%. CAS No. 53948-09-7. Molecular formula: C17H13NO3. Mole weight: 279.3. | |
| Aristolone | Aristolone. Group: Biochemicals. Alternative Names: 9-Aristolen-8-one. Grades: Plant Grade. CAS No. 25274-27-5. Pack Sizes: 20mg. Molecular Formula: C15H22O, Molecular Weight: 218.335. US Biological Life Sciences. | Worldwide |
| Arisugacin A | Arisugacin is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259. Synonyms: Arisugacin; (4aR,6aR,12aS,12bS)-9-(3,4-dimethoxyphenyl)-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione. Grade: >98%. Molecular formula: C28H32O8. Mole weight: 496.55. | |
| Arisugacin B | Arisugacin B is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259. Synonyms: (4aR,6aR,12aS,12bS)-4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione. Molecular formula: C27H30O7. Mole weight: 466.52. | |
| Arisugacin H | Arisugacin H is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4260. Molecular formula: C29H36O9. Mole weight: 528.59. | |
| Arizonin A1 | Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin A1 has anti-Gram-positive bacteria activity. Synonyms: 2H-Furo(3,2-b)naphtho(2,3-d)pyran-2,6,11-trione, 3,3a,5,11b-tetrahydro-8-hydroxy-7-methoxy-5-methyl-, (3aR-(3aalpha,5alpha,11balpha))-; Arizonin-A1. CAS No. 108890-87-5. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| Arizonin B1 | Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin B1 has anti-Gram-positive bacteria activity. Synonyms: Arizonin-B1; (3ar,5r,11br)-7-hydroxy-8-methoxy-5-methyl-3,3a,5,11b-tetrahydro-2h-benzo[g]furo[3,2-c]isochromene-2,6,11-trione. CAS No. 108890-89-7. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| Arjunic acid | Arjunic acid isolated from the stem bark of Terminalia arjuna. It shows activity against Gram-positive and Gram-negative bacteria. Uses: A strong antioxidant and a free radical scavenger. Synonyms: 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid. Grade: 95%. CAS No. 31298-06-3. Molecular formula: C30H48O5. Mole weight: 488.7. | |
| Arjunic acid | analytical standard. Group: Herbal medicinal products standards. | |
| Arjunolic acid | Arjunolic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 465-00-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C30H48O5. US Biological Life Sciences. | Worldwide |
| Arjunolic acid | Arjunolic acid is a natural triterpenoid isolated from the fruits of Terminalia chebula Retz, it has antioxidant properties and plays protective roles against chemically induced organ pathophysiology. Arjunolic acid can protect cardiac tissues from both extrinsic and intrinsic cell death pathways. Uses: Antioxidant. Synonyms: 2,3,23-Trihydroxy-12-oleanen-28-oic acid. Grade: >98%. CAS No. 465-00-9. Molecular formula: C30H48O5. Mole weight: 488.7. | |
| Arjunolic acid | Arjunolic acid is a saponin isolated from Cyclocarya paliurus and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potent antioxidant and plays an important role in the protection of cells and tissues against deleterious effects of reactive oxygen species [1]. Uses: Scientific research. Group: Natural products. CAS No. 465-00-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2896. | |
| AR-L 100 BS | AR-L 100 BS is a bio-active chemical with cardiovascular effects originated by oehringer Ingelheim Pharma KG. But no development was reported for Ischaemic heart disorders till now. Uses: Ischaemic heart disorders. Synonyms: AR-L 100 BS; AR-L-100BS; AR-L100 BS; BRN 0842454; 2-(4-Methoxy-2-(2-(methylsulfinyl)ethoxy)phenyl)-1H-imidazo(4,5-b)pyridine. Grade: 98%. CAS No. 77303-18-5. Molecular formula: C16H17N3O3S. Mole weight: 331.39. | |
| ARL 17477 dihydrochloride | The hydrochloride salt form of ARL 17477, which has been found to be a nitric oxide synthase (NOS) inhibitor and could induce apoptosis/cell death in leukemia cells. Synonyms: 2-Thiophenecarboximidamide, N-[4-[2-[[(3-chlorophenyl)methyl]amino]ethyl]phenyl]-, hydrochloride (1:2); 2-Thiophenecarboximidamide, N-[4-[2-[[(3-chlorophenyl)methyl]amino]ethyl]phenyl]-, dihydrochloride; ARL17477 dihydrochloride; ARL-17477 dihydrochloride; N-[4-[2-[[(3-Chlorophenyl)methyl]amino]ethyl]phenyl]-2-thiophenecarboxamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 866914-87-6. Molecular formula: C20H20ClN3S.2HCl. Mole weight: 442.83. | |
| ARL-17477 dihydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ARL 67156 | ARL 67156 is an ecto-ATPase inhibitor/ATP analog. Synonyms: ARL 67157; FPL 67156. CAS No. 160928-38-1. Molecular formula: C15H24Br2N5O12P3. Mole weight: 719.11. | |
| ARL67156 trisodium | ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase , CD39 , and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12 μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 67156 trisodium. CAS No. 1021868-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103265. | |
| ARL 67156 trisodium salt | ARL 67156 trisodium salt. Group: Biochemicals. Grades: Purified. CAS No. 1021868-83-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ARL 67156 trisodium salt | The sodium salt form of ARL 67156, which has been found to be an ecto-ATPase inhibitor. Synonyms: ARL 67156; ARL-67156; ARL67156; 6-N,N-Diethyl-D-β,γ-dibromomethyleneATP trisodium salt. Grade: ≥98% by HPLC. CAS No. 1021868-83-6. Molecular formula: C15H21Br2N5O12P3.3Na. Mole weight: 785.06. | |
| ARL 67156 trisodium salt hydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| ARM1 | ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC 50 7.61 μM and epoxide hydrolase inhibitory activity with an IC 50 12.4 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4BSA. CAS No. 68729-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W027340. | |
| AR-M 1000390 hydrochloride | AR-M 1000390 hydrochloride is an agonist of δ-selective opioid receptor with an analgesic effect. AR-M 1000390 hydrochloride can reduce CFA-induced hyperalgesia. Uses: Arm-390hcl is an agonist of δ-selective opioid receptor with an analgesic effect. Synonyms: ARM-390 HCl; ARM 390 HCl; ARM390 HCl; ARM 1000390 hydrochloride; ARM1000390 hydrochloride; N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)benzamide Monohydrochloride. Grade: ≥97% by HPLC. CAS No. 209808-47-9. Molecular formula: C23H29ClN2O. Mole weight: 384.94. | |
| AR-M 1000390 hydrochloride | AR-M 1000390 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 209808-47-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AR-M 1896 | AR-M 1896. Group: Biochemicals. Grades: Purified. CAS No. 367518-31-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AR-M 1896 acetate | AR-M 1896 acetate is the selective galanin GAL2 receptor agonist used as an antiepileptogenic agent. Synonyms: H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2.CH3CO2H; L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucinamide acetic acid. Grade: ≥95%. Molecular formula: C56H85N13O16. Mole weight: 1196.35. | |
| ARM1 hydrobromide | ARM1 hydrobromide is a novel Leukotriene A4 hydrolase/aminopeptidase (LTA4H) inhibitor (IC50 value of ~0.5 μM in human neutrophils, and Ki value of 2.3 μM for purified LTA4H) that blocks the conversion of LTA4 into proinflammatory mediator LTB4, although leaving the aminopeptidase activity intact for cleavage and inactivation of Pro-Gly-Pro. Synonyms: ARM1 hydrobromide; ARM 1 hydrobromide; ARM-1 hydrobromide; 4-(4-benzylphenyl)-1,3-thiazol-2-amine hydrobromide. Grade: 99%. CAS No. 1049743-03-4. Molecular formula: C16H14N2S.HBr. Mole weight: 347.27. | |
| ARM390 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Armeniaspirol A | Armeniaspirol A is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Synonyms: Armeniaspirole A. CAS No. 1206881-47-1. Molecular formula: C18H19Cl2NO4. Mole weight: 384.25. | |
| Armeniaspirol B | Armeniaspirol B is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Synonyms: Armeniaspirole B. CAS No. 1206881-48-2. Molecular formula: C18H19Cl2NO4. Mole weight: 384.25. | |
| Armeniaspirol C | Armeniaspirol C is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Synonyms: Armeniaspirole C. CAS No. 1206881-49-3. Molecular formula: C19H21Cl2NO4. Mole weight: 398.28. | |
| Armentomycin | Armentomycin is an antibiotic produced by Streptomyces armentosus var. armentosus. Armentomycin mainly acts against gram-negative bacteria. Subcutaneous administration of 25mg/kg in mice appears toxic. Synonyms: (S)-2-amino-4,4-dichlorobutanoic acid. Grade: >98%. CAS No. 10139-00-1. Molecular formula: C4H7Cl2NO2. Mole weight: 172.01. | |
| Armillyl orsellinate | Armillyl orsellinate is an antibiotic produced by Armillaria mellea 619, which has activity against gram-positive bacteria. Molecular formula: C23H30O6. Mole weight: 402.48. | |
| Arminin-1a | Arminin-1a is a novel antimicrobial peptide discovered during investigations of the epithelial defense of the ancient metazoan Hydra. | |
| ARN 14686 | ARN14686 is a NAAA (N-acylethanolamine acid amidase) activity-based protein profiling (ABPP) probe. ARN14686 can be used to detect NAAA by using click chemistry in cell lysates or intact cells, which binds covalently to the N-terminal cysteine of catalytically active NAAA to form a thioester adduct. ARN14686 inhibits the hydrolysis of the NAAA substrate PAMCA in HEK293 cells. The IC50s for human is 6 and the IC50s for rat recombinant enzymes is 13 nM. Synonyms: (S)-Undec-10-yn-1-yl (2-oxoazetidin-3-yl)carbamate. Grade: ≥98% by HPLC. CAS No. 1628345-10-7. Molecular formula: C15H24N2O3. Mole weight: 280.36. | |
| ARN14974 | ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase with IC50 of 79 nM. It inhibits acid ceramidase activity, reduces levels of sphingosine and dihydroceramide, and increases levels of ceramide in SW403 adenocarcinoma cells and RAW 264.7 murine macrophages when used at concentrations ranging from 0.1 to 20 mM. Synonyms: Acid Ceramidase Inhibitor 17a; ARN-14974; ARN 14974; Acid Ceramidase Inhibitor 17a. Grade: ≥95%. CAS No. 1644158-57-5. Molecular formula: C24H21FN2O3. Mole weight: 404.4. | |
| ARN14988 | ARN14988 can normalize ceramide levels and concomitantly sensitize proliferative melanoma cells to the cytotoxic actions of various antitumoral agents. ARN14988 is a potent inhibitor of acid ceramidase with IC50 of 12.8 nM for the human enzyme. ARN14988 also reduces growth of A375 with EC50s of 41.8 μM and G361 with EC50s of 67.7 μM. Synonyms: ARN 14988; ARN-14988. Grade: ≥98%. CAS No. 1502027-70-4. Molecular formula: C16H24ClN3O5. Mole weight: 373.83. | |
| ARN19702 | ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 230 nM for human NAAA. Synonyms: ARN-19702; ARN 19702. Grade: 98% by HPLC. CAS No. 1971937-18-4. Molecular formula: C21H22FN3O3S2. Mole weight: 447.6. | |
| ARN19702 | ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 230 nM for human NAAA. ARN19702 has pain relief effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1971937-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145339. | |
| ARN19874 | ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) with IC50 of 33.7 μM. ARN19874 is the first selective, cell-active inhibitor of NAPE-PLD. It is significantly less potent on the Q320A mutant, and it can cause a substantial accumulation of non-metabolized NAPE species iuman HEK-293 cells at 50 uM. Uses: Enzyme inhibitors. Synonyms: 2,4-dioxo-N-[4-(4-pyridyl)phenyl]-1H-quinazoline-6-sulfonamide. Grade: ≥98%. CAS No. 2190502-57-7. Molecular formula: C19H14N4O4S. Mole weight: 394.41. | |
| ARN-21934 | ARN-21934 is a potent, highly selective and blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. Compared with anticancer agent Etoposide (IC50 = 120 μM), ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM. It is a promising anticancer lead compound with good pharmacokinetic profile in vivo. Synonyms: 4,6-Quinazolinediamine, N4-[4-(dimethylamino)phenyl]-5,6,7,8-tetrahydro-2-(4-pyridinyl)-; N4-[4-(Dimethylamino)phenyl]-2-(4-pyridinyl)-5,6,7,8-tetrahydro-4,6-quinazolinediamine. Grade: ≥98%. CAS No. 2230854-93-8. Molecular formula: C21H24N6. Mole weight: 360.46. | |
| ARN24139 | ARN24139 is an orally active topoisomerase II poison with an IC50 of 7.3 μM. Synonyms: 6-Hydroxy-4-oxo-1,3-diphenyl-2-thioxo-N-(3-(trifluoromethoxy)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide. Grade: 99%. CAS No. 2699768-78-8. Molecular formula: C24H16F3N3O4S. Mole weight: 499.46. | |
| ARN 272 | ARN 272 has been found to be a FLAT inhibitor and could show analgesic activities in CB1-mediated nociceptive and inflammatory pain. Synonyms: ARN272; ARN-272; ARN 272; 4-[[4-(4-Hydroxyphenyl)-1-phthalazinyl]amino]-N-phenylbenzamide. Grade: ≥98% by HPLC. CAS No. 488793-85-7. Molecular formula: C27H20N4O2. Mole weight: 432.47. | |
| ARN 272 | ARN 272. Group: Biochemicals. Grades: Purified. CAS No. 488793-85-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ARN2966 | ARN2966, also called 2-PMAP, as a Amyloid-β inhibitor, is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: 2-(pyridin-2-ylmethylamino)phenol; 2-PMAP; ARN2966; ARN-2966; Phenol, 2-[(2-pyridinylmethyl)amino]-; 102212-26-0; AGN-PC-0031SD; GTPL7530; 2-(2-Pyridylmethylamino)phenol; SCHEMBL10886688; AOB1080; SYN5152; 2-(pyridin-2-ylmethylamino)phenol; 3970AH; ZINC34411048; AKOS022987680; CS-3335; HY-18292; ARN-2966; CS 3335; HY 18292; ARN 2966; CS3335; HY18292; ARN2966. Grade: > 98%. CAS No. 102212-26-0. Molecular formula: C12H12N2O. Mole weight: 200.24. | |
| ARN-3236 | ARN-3236 is an orally available and selective inhibitor of salt-inducible kinase 2 (SIK2). Study shows that ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. Synonyms: 3-(2,4-dimethoxyphenyl)-4-(thiophen-3-yl)-1H-pyrrolo[2,3-b]pyridine; 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine. CAS No. 1613710-01-2. Molecular formula: C19H16N2O2S. Mole weight: 336.41. | |
| ARN-3236 | ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856. | |
| ARN-5187 | ARN-5187, a piperazin derivative, has been found to be a REV-ERBβ inhibitor that could induce apoptotic in cancer cells and probably be more effective in breast cancer cells. Synonyms: ARN5187; ARN-5187; ARN 5187; 4-(((1-(2-fluorophenyl)cyclopentyl)amino)methyl)-2-((4-methylpiperazin-1-yl)methyl)phenol hydrochloride. Grade: 98%. CAS No. 1700693-96-4. Molecular formula: C24H33ClFN3O. Mole weight: 434.00. | |
| ARN726 | ARN726 is a systemically active and orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 value of 27 nM for human and 63 nM for rat NAAA. The selectivity for NAAA is better than fatty acid amide hydrolase (FAAH) with IC50s of 100 uM. It is also selective over acid cermidase with IC5Os of 12.5 uM. ARN726 can decrease lung myeloperoxidase activity and pleural exudate TNF-α levels in a mouse model of carrageenan-induced lung inflammation. Synonyms: ARN-0726; ARN 0726. Grade: ≥95%. CAS No. 1628343-77-0. Molecular formula: C14H24N2O3. Mole weight: 268.35. | |
| ARND'S ALLOY | ARND'S ALLOY. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ARND'S ALLOY. Product Category: Heterocyclic Organic Compound. CAS No. 51636-39-6. Molecular formula: CuMg. Purity: 0.96. Product ID: ACM51636396. Alfa Chemistry ISO 9001:2015 Certified. | |
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