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Arnica Extract. Applications: Boost the blood move.anti-inflammation have effect in epilepsy , trauma and pelagism. Group: Others. Synonyms: Arnica Extract; Arnica montana. Purity: 5-10:1 By TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Whole plant. Species: Arnica montana. Arnica Extract; Arnica montana; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-176.
Arnifolin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID6450253, CID 6450253, 2-Butanoic acid, 2-methyl-, dodecahydro-7-hydroxy-4a,8-dimethyl-3-methylene-2,5-dioxoazuleno(6,5-b)furan-4-yl ester, 25644-08-0. Appearance: White powder. CAS No. 25644-08-0. Molecular formula: C20H26O6. Mole weight: 362.42. Purity: 97%+. IUPACName: (6-hydroxy-5,8a-dimethyl-1-methylidene-2,8-dioxo-3a,4,5,5a,6,7,9,9a-octahydroazuleno[6,5-b]furan-9-yl) (E)-2-methylbut-2-enoate. Canonical SMILES: CC=C(C)C(=O)OC1C2C(CC(C3C1(C(=O)CC3O)C)C)OC(=O)C2=C. Density: 1.23g/cm³. Product ID: ACM25644080. Alfa Chemistry ISO 9001:2015 Certified.
certified reference material, pkg of 50 g. Group: Certified reference materials (crms).
Aroclor 1242 - Loam
certified reference material, pkg of 50 g. Group: Certified reference materials (crms).
Aroclor 1242 - Sandy Loam
certified reference material, pkg of 50 g. Group: Certified reference materials (crms).
Aroclor 1254 - Silt Loam
certified reference material, pkg of 50 g. Group: Certified reference materials (crms).
Aroclor 1260-Sandy Loam
certified reference material, pkg of 50 g. Group: Certified reference materials (crms).
Aroclor 1260 - Transformer Oil
certified reference material, pkg of 10 g. Group: Certified reference materials (crms).
arogenate dehydratase
Also acts on prephenate and D-prephenyllactate. cf. EC 4.2.1.51, prephenate dehydratase. Group: Enzymes. Synonyms: carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase (decarboxylating). Enzyme Commission Number: EC 4.2.1.91. CAS No. 76600-70-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5075; arogenate dehydratase; EC 4.2.1.91; 76600-70-9; carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase (decarboxylating). Cat No: EXWM-5075.
arogenate dehydrogenase
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). NAD+-specific enzymes have been reported from some bacteria and plants. Some enzymes also possess the activity of EC 1.3.1.12, prephenate dehydrogenase. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous); L-arogenate:NAD+ oxidoreductase; arogenate dehydrogenase (NAD+). Enzyme Commission Number: EC 1.3.1.43. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1315; arogenate dehydrogenase; EC 1.3.1.43; 64295-75-6; arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous); L-arogenate:NAD+ oxidoreductase; arogenate dehydrogenase (NAD+). Cat No: EXWM-1315.
arogenate dehydrogenase (NADP+)
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). NADP+-dependent enzymes usually predominate in higher plants.The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 and the TyrAAT1 isoform of the plant Arabidopsis thaliana cannot use prephenate as a substrate, while the Arabidopsis isoform TyrAAT2 can use it very poorly. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); pretyrosine dehydrogenase (ambiguous); TyrAAT1; TyrAAT2; TyrAa. Enzyme Commission Number: EC 1.3.1.78. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1347; arogenate dehydrogenase (NADP+); EC 1.3.1.78; 64295-75-6; arogenic dehydrogenase (ambiguous); pretyrosine dehydrogenase (ambiguous); TyrAAT1; TyrAAT2; TyrAa. Cat No: EXWM-1347.
arogenate dehydrogenase [NAD(P)+]
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). Enzymes that can utilize both cofactors have been reported from some Proteobacteria, including Burkholderia caryophylli, Burkholderia cepacia, Pseudomonas marginata and Delftia acidovorans. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.3.1.79. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1348; arogenate dehydrogenase [NAD(P)+]; EC 1.3.1.79; 64295-75-6; arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous). Cat No: EXWM-1348.
Arohynapene A
Arohynapene A is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. Arohynapene A has no antibacterial activity. Synonyms: 5-(5-Hydroxy-2,6,8-trimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-5-hydroxy-2,6,8-trimethyl-1-naphthalenyl)-. CAS No. 154445-08-6. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene B
Arohynapene B is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. It has no antibacterial activity. Synonyms: 5-(2-Hydroxymethyl-6,8-dimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-2-(hydroxymethyl)-6,8-dimethyl-1-naphthalenyl)-. CAS No. 154445-09-7. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene D
Arohynapene D is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. The MIC that Arohynapene D shows toxicity to BHK-21 cells is 1.0 X 10-6 mol/L. Molecular formula: C11H14O3. Mole weight: 194.23.
Aromadendrene
Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Aromadendrene. CAS No. 489-39-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8411.
Aromadendrin
Aromadendrin, which usually comes from the bark of Eucalyptus calophylla, exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells. Aromadendrin may represent a potential therapeutic candidate for the management of type 2 DM. Uses: Anti-inflammatory/antioxidant/anti-diabetic. Synonyms: 3,5,7,4'-Tetrahydroxyflavanone; Dihydrokaempferol; aromadedrin; (2R)-2,3-Dihydro-3β,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2R,3R)-2,3-Dihydro-2-(4-hydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Katuranin. Grade: >98%. CAS No. 480-20-6. Molecular formula: C15H12O6. Mole weight: 288.3.
Aromadendrin 7-O-rhamnoside
Aromadendrin 7-O-rhamnoside, a flavonoid compound present in numerous plant species, exhibits considerable efficacy as an antioxidant and anti-inflammatory agent, and is considered to have therapeutic potential in diverse pathological conditions including cancer and diabetes. Its efficacy can be attributed to its natural composition making it a plausible resource for discovery of novel pharmacological targets in the nutraceutical and pharmaceutical sectors. Synonyms: (2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one. Grade: 97.5%. CAS No. 69135-41-7. Molecular formula: C21H22O10. Mole weight: 434.39.
aromatase
A cytochrome P-450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17β-estradiol, respectively. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: CYP19A1 (gene name); estrogen synthetase (incorrect). Enzyme Commission Number: EC 1.14.14.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0911; aromatase; EC 1.14.14.14; CYP19A1 (gene name); estrogen synthetase (incorrect). Cat No: EXWM-0911.
Aromatase-IN-2
Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430.
aromatic-amino-acid-glyoxylate transaminase
Phenylalanine, kynurenine, tyrosine and histidine can act as amino donors; glyoxylate, pyruvate and hydroxypyruvate can act as amino acceptors. Group: Enzymes. Enzyme Commission Number: EC 2.6.1.60. CAS No. 67185-76-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2902; aromatic-amino-acid-glyoxylate transaminase; EC 2.6.1.60; 67185-76-6. Cat No: EXWM-2902.
aromatic-amino-acid transaminase
A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC 2.6.1.1 aspartate transaminase. Group: Enzymes. Synonyms: aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Enzyme Commission Number: EC 2.6.1.57. CAS No. 37332-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2898; aromatic-amino-acid transaminase; EC 2.6.1.57; 37332-38-0; aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Cat No: EXWM-2898.
Aromatic hydrocarbons, C6-10, C8-rich
Aromatic hydrocarbons, C6-10, C8-rich. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aromatic hydrocarbons, C6-10, C8-rich;Aromatic hydrocarbons, C6-10, C8-rich Light Oil Redistillate, low boiling. Product Category: Heterocyclic Organic Compound. CAS No. 90989-41-6. Product ID: ACM90989416. Alfa Chemistry ISO 9001:2015 Certified.
Transfers the N-acetyl group of some aromatic acethydroxamates to the O-position of some aromatic hydroxylamines. Group: Enzymes. Synonyms: aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Enzyme Commission Number: EC 2.3.1.56. CAS No. 52660-15-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2235; aromatic-hydroxylamine O-acetyltransferase; EC 2.3.1.56; 52660-15-8; aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Cat No: EXWM-2235.
aromatic-L-amino-acid decarboxylase
A pyridoxal-phosphate protein. The enzyme also acts on some other aromatic L-amino acids, including L-tryptophan, L-tyrosine and L-phenylalanine. Group: Enzymes. Synonyms: DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Enzyme Commission Number: EC 4.1.1.28. CAS No. 9042-64-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4771; aromatic-L-amino-acid decarboxylase; EC 4.1.1.28; 9042-64-2; DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Cat No: EXWM-4771.
Aromatics Content Standard
ASTM D 5580 (26.78%). Group: Certified reference materials (crms).
Aromatic solvents
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Aronia P.E. 4:1
Aronia P.E. 4:1.
CA, FL & NJ
Aroplatin
Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. The liposomal encapsulation improves the bioavailability of NDDP and reduces its toxicity profile. CAS No. 114488-24-3. Molecular formula: C26H52N2O4Pt. Mole weight: 651.79.
Arotinoid
Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors ( RARs ) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED 50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6298; Arotinoid ethyl ester. CAS No. 71441-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106735.
Arotinolol
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 68377-92-4. Pack Sizes: 100mg, 1g. Molecular Formula: C15H21N3O2S3. US Biological Life Sciences.
Worldwide
Arotinolol
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker [1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125 I-ICYP to 5HT 1B -serotonergic receptor sites [2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68377-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122537A.
Arotinolol
Arotinolol is a medication used primarily for the treatment of hypertension and certain types of arrhythmias. Arotinolol is a non-selective beta-adrenergic receptor antagonist (beta-blocker) that blocks both beta-1 and beta-2 receptors. This action reduces the effects of adrenaline and noradrenaline, leading to a decrease in heart rate and blood pressure. In addition to its beta-blocking properties, arotinolol also exhibits alpha-1 adrenergic receptor antagonism. This action leads to vasodilation and further reduction in blood pressure. Arotinolol is used to treat high blood pressure, helping to prevent complications such as stroke, heart attack, and kidney problems. It can be used to manage certain types of cardiac arrhythmias (irregular heartbeats). Arotinolol may be used to alleviate symptoms of angina, a condition characterized by chest pain due to reduced blood flow to the heart. Synonyms: 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-; 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-, (±)-; 5-[2-[[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-2-thiophenecarboxamide; (±)-Arotinolol; 2-(3-tert-Butylamino-2-hydroxypropylthio)-4-(5-carbamoyl-2-thienyl)thiazole; NSC 317940. Grade: ≥95%. CAS No. 68377-92-4. Molecular formula: C15H21N3O2S3. Mole weight: 371.54.
Arotinolol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[2-[[3-(tert-Butylamino)-2-hydroxypropyl]thio]thiazol-4-yl]thiophene-2-carboxamide Hydrochloridel. Product Category: Thiophenes. CAS No. 68377-91-3. Molecular formula: C15H22ClN3O2S3. Mole weight: 407.99. Purity: 0.98. Product ID: ACM68377913. Alfa Chemistry ISO 9001:2015 Certified.
Arotinolol impurity 8
Arotinolol impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1682660-95-2. Molecular formula: C8H6N2O2S2. Mole weight: 226.27. Catalog: APB1682660952.
ARP 100
ARP 100. Group: Biochemicals. Grades: Purified. CAS No. 704888-90-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ARP 100
ARP 100 has been found to be a selective inhibitor of MMP-2 and could show anti-invasive properties in HT1080 fibrosarcoma cells at some extent. Synonyms: ARP100; ARP-100; ARP 100; 2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide. Grade: ≥98% by HPLC. CAS No. 704888-90-4. Molecular formula: C17H20N2O5S. Mole weight: 364.42.
ARP-100
ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1? pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 ?M), MMP-3 (4.5 ?M), MMP-7 (>50 ?M), and MMP-9 (0.2 ?M)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 704888-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103444.
ARP 101
ARP 101 is a Selective MMP-2 inhibitor with IC50 value of 0.81 nM. It displays nearly 600-fold selectivity over MMP-1 (IC50 value 486 nM). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis and so on. Synonyms: ARP-101; ARP 101; ARP101; (2R)-N-hydroxy-3-methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanamide. Grade: 98%. CAS No. 849773-63-3. Molecular formula: C20H26N2O5S. Mole weight: 406.50.
ARP 101
ARP 101. Group: Biochemicals. Grades: Purified. CAS No. 849773-63-3. Pack Sizes: 5mg. US Biological Life Sciences.
Arphamenine a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Arphamenine A, Arphamenine A hydrochloride, C16H24N4O3.HCl, CID5487157, LS-31060, 5-amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid, 5-Amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid hydrochloride, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-, monohydrochloride, (S-(R*,S*))-, 85713-14-0, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-,monohydrochloride, (S-(R*,S*))-. Product Category: Heterocyclic Organic Compound. CAS No. 85713-14-0. Molecular formula: C32H50N8O10S. Mole weight: 356.847700 [g/mol]. Purity: 0.96. IUPACName: (2R,5S)-5-amino-2-benzyl-8-(diaminomethylideneamino)-4-oxooctanoic acid hydrochloride. Product ID: ACM85713140. Alfa Chemistry ISO 9001:2015 Certified.
Arphamenine A
Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grade: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39.
Arphamenine A hemisulfate
Arphamenine A hemisulfate is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Arphamenine A sulfate; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-, sulfate (2:1); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, sulfate, [S-(R*,S*)]-; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid sulfate (2:1). Grade: >98%. CAS No. 144110-37-2. Molecular formula: C16H24N4O3.1/2H2O4S. Mole weight: 369.43.
Arphamenine A hydrochloride
Arphamenine A hydrochloride is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, monohydrochloride, [S-(R*,S*)]-; Arphamenine A monohydrochloride; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid hydrochloride (1:1); Benzenepropanoic acid, α-[(3S)-3-amino-6-[(diaminomethylene)amino]-2-oxohexyl]-, (αR)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 85713-14-0. Molecular formula: C16H24N4O3.HCl. Mole weight: 356.85.
Arphamenine B
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grade: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39.
Arphamenine B hemisulfate
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grade: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43.
Arphamenine B hydrochloride
Arphamenine B is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-; Arphamenine B monohydrochloride; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, monohydrochloride; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid monohydrochloride. Grade: ≥95%. CAS No. 88465-81-0. Molecular formula: C16H24N4O4.HCl. Mole weight: 372.85.
Arprinocid
A Coccidiostat used in veterinary medicine. Group: Biochemicals. Alternative Names: 9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purin-6-amine; 6-Amino-9-(2-chloro-6-fluorobenzyl)purine; Arpocox; MK 302. Grades: Highly Purified. CAS No. 55779-18-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Arprinocid
Arprinocid is a coccidiostat used in veterinary medicine. Uses: Coccidiostats. Synonyms: Arpocox; Arprinocide; MK302; MK-302; MK 302; 9-(2-Chloro-6-fluorobenzyl)-9H-purin-6-amine; 6-Amino-9-(2-chloro-6-fluorobenzyl)purine. CAS No. 55779-18-5. Molecular formula: C12H9ClFN5. Mole weight: 277.69.
ARQ 069
ARQ 069 is an analogue of ARQ 523 and inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases with IC50s of 0.84 and 1.23 μM, respectively. It inhibits FGFR1/FGFR2 autophosphorylation through a non-ATP competitive dependent mechanism with IC50s of 2.8 and 1.9 μM, respectively. Synonyms: Benzo[h]quinazolin-2-amine, 5,6-dihydro-6-phenyl-, (6S)-; 3RH. Grade: ≥95%. CAS No. 1314021-57-2. Molecular formula: C18H15N3. Mole weight: 273.33.
ARQ-087
ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Synonyms: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. Grade: ≥98%. CAS No. 1234356-69-4. Molecular formula: C29H29FN4O. Mole weight: 468.576.
ARQ-092
ARQ-092, also called as Miransertib, is an oral activie, potent and selective AKT inhibitor with IC50=5.0 nM against AKT1, 4.5 nM against AKT2 and 16 nM against AKT3. ARQ-092 inhibits the PI3K/AKT signaling pathway due to inhibition of the activity of AKT in a non-ATP competitive manner. This may lead to the reduction in tumor cell proliferation and the induction of tumor cell apoptosis. Synonyms: 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine; ARQ092; ARQ-092; ARQ 092; Miransertib. Grade: >98%. CAS No. 1313881-70-7. Molecular formula: C27H24N6. Mole weight: 432.53.
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity. ARQ 531 is a reversible non-covalent inhibitor of Bruton's Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases. In GCB-DLBCL cell lines (SUDHL-4 and DOHH-2), ARQ 531 potently suppressed expression of anti-apoptotic c-Myc and BCL6 oncoproteins in a dose-dependent fashion, and concomitantly induced apoptotic cleavage of PARP protein. Synonyms: ARQ-531. Grade: ≥98%. CAS No. 2095393-15-8. Molecular formula: C25H23ClN4O4. Mole weight: 478.93.
ARQ-621
ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies. Synonyms: NSC-771644; N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluorobenzamide; (R)-N-(3-Aminopropyl)-3-chloro-N-(1-(7-chloro-4-oxo-3-(phenylamino)-3,4-dihydroquinazolin-2-yl)but-3-yn-1-yl)-2-fluorobenzamide; Benzamide, N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-. Grade: ≥95%. CAS No. 1095253-39-6. Molecular formula: C28H24Cl2FN5O2. Mole weight: 552.43.
ARQ 736
ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. Synonyms: ARQ 736; ARQ736; ARQ-736. CAS No. 1228237-47-5. Molecular formula: C25H25N8Na2O8PS. Mole weight: 630.569.
ARQ 736 disodium salt
This active molecular is a Proto oncogene protein b raf and Vascular endothelial growth factor A inhibitor originated by ArQule. ARQ 736 is effective in killing cancer cell lines that harboring at least one mutated b raf allele. The b raf protein is really a very important signaling molecule in the MAPK (mitogen activated protein kinase) signaling pathway and it relates to pathogenesis of variety kinds of cancer. In Mar 2014, Phase-I for Solid tumours (late-stage disease) was discontinued in USA. Uses: Solid tumours. Synonyms: ARQ 736 disodium salt; ARQ736 disodium salt; ARQ-736 disodium salt; sodium (R)-(3-(5-(2-((1-((1-methyl-1H-pyrazol-3-yl)sulfonyl)piperidin-3-yl)amino)pyrimidin-4-yl)imidazo[2,1-b]oxazol-6-yl)phenoxy)methyl phosphate; 1228237-47-5 free acid. Grade: 98%. CAS No. 1228237-57-7. Molecular formula: C25H25N8Na2O8PS. Mole weight: 674.54.
AR-R 17779 hydrochloride
AR-R17779 has been found to be a selective alpha7 nicotinic agonist and could probably reduce blood pressure and serum lipid levels. Synonyms: AR-R 17779 hydrochloride; AR-R-17779 hydrochloride; AR-R17779 hydrochloride; ARR17779 hydrochloride; (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidine]-2'-one hydrochloride. Grade: ≥98% by HPLC. CAS No. 178419-42-6. Molecular formula: C9H14N2O2.HCl. Mole weight: 218.68.
AR-R17779 hydrochloride
AR-R17779 hydrochloride is a potent and selective full agonist of nAChR , with K i s of 92 and 16000 nM for α7 and α4β2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178419-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135483A.