A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Synonyms: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grades: 99%. CAS No. 836620-48-5. Molecular formula: C18H22FN3O3. Mole weight: 347.38.
AS-186c
AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Synonyms: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82.
AS-186d
AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Synonyms: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86.
AS 1892802
AS 1892802 has been found to be an ATP-competitive ROCK inhibitor and could show analgesic activities at some extent. Synonyms: AS 1892802; AS1892802; AS-1892802; N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea. Grades: ≥99% by HPLC. CAS No. 928320-12-1. Molecular formula: C20H19N3O2. Mole weight: 333.38.
AS 1892802
AS 1892802. Group: Biochemicals. Grades: Purified. CAS No. 928320-12-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AS 19
Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced. Group: Biochemicals. Alternative Names: (2S) - (+) -5- (1, 3, 5-Trimethylpyrazol-4-yl) -2- (dimethylamino) tetralin. Grades: Highly Purified. CAS No. 1000578-26-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 283.41. US Biological Life Sciences.
Worldwide
AS 19
AS 19 has been found to be a potent SR-7 agonist and could probably enhance memory consolidation. Synonyms: AS 19; AS-19; AS19; (2S)-(+)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin. Grades: ≥98% by HPLC. CAS No. 1000578-26-6. Molecular formula: C18H25N3. Mole weight: 283.41.
AS1940477
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent concentrations of AS1940477 that inhibited cytokine production also inhibited TNFα- and IL-1 β-induced production of IL-6, PGE(2), and MMP-3 in human synovial stromal cells. AS1940477 was also found to potently inhibit TNF production in whole blood (IC(50)=12 nM) and effectively inhibited TNFα production induced by systemically administered LPS in rats at less than 0.1mg/kg (ED(50)=0.053 mg/kg) with an anti-inflammatory effect lasting for 20h after oral administration. Overall, this study demonstrated that AS1940477 is a novel and potent p38 MAPK inhibitor and may be useful as a promising anti-inflammatory agent for treating inflammatory disorders. Synonyms: AS1940477; AS-1940477; AS 1940477. CAS No. 928344-12-1. Molecular formula: C24H22FN5O2. Mole weight: 431.47.
AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 μM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1203680-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18686.
AS 1949490
AS1949490 has been found to be a selective SHIP2 phosphatase inhibitor and show antidiabetic activities. Synonyms: AS1949490; AS-1949490; AS 1949490; 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide. Grades: ≥99% by HPLC. CAS No. 1203680-76-5. Molecular formula: C20H18ClNO2S. Mole weight: 371.88.
AS 1949490
AS 1949490. Group: Biochemicals. Grades: Purified. CAS No. 1203680-76-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AS 2034178
AS 2034178. Group: Biochemicals. Grades: Purified. CAS No. 1030846-42-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AS 2034178
AS 2034178 has been found to be a FFA1/GPR40 agonist and could probably be used against diabetes. Synonyms: AS 2034178; AS2034178; AS-2034178; 2-Fluoro-4- [ [ [1, 2, 3, 4-Tetrahydro-1- (2-phenoxyethyl) -5-quinolinyl] methyl] amino] benzenepropanoic acid. Grades: ≥98% by HPLC. CAS No. 1030846-42-4. Molecular formula: C27H29FN2O3. Mole weight: 448.53.
AS-2444697 is a pootent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50 = 21 nM) with 30-fold selectivity for IRAK4 over IRAK1. AS2444697 significantly reduced or showed a decreasing trend in expression and levels of these inflammatory parameters. Synonyms: N-(3-carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide hydrochloride; AS-2444697; AS 2444697; AS2444697; AS-2444697 HCl; AS-2444697 hydrochloride. CAS No. 1287665-60-4. Molecular formula: C19H21ClN6O4. Mole weight: 432.86.
AS 252424
AS 252424. Group: Biochemicals. Grades: Purified. CAS No. 900515-16-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AS-252424
AS-252424 is a novel, potent PI3Kγ inhibitor (IC50 of 30 nM) with a 30-fold selectivity for PI3Kγ than PI3Kα, and low inhibitory activity towards PI3Kδ/&beta. Synonyms: AS252424; AS 252424; AS-252424. Grades: >98%. CAS No. 900515-16-4. Molecular formula: C14H8FNO4S. Mole weight: 305.28.
AS 252424 bispotassium salt is the potassium salt form of AS 252424, which is a potent and selective PI3K p110γ inhibitor. Synonyms: AS 252424 bispotassium salt; AS252424 bispotassium salt; AS-252424 bispotassium salt; dipotassium (5Z)-5-[[5-(4-fluoro-2-oxidophenyl)furan-2-yl]methylidene]-4-oxo-1,3-thiazol-2-olate. Grades: 99%. Molecular formula: C14H6FNO4S.K2. Mole weight: 381.46.
AS2717638
AS2717638 is a highly selective, brain-penetrant and orally active lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 38 nM. AS2717638 is highly selective and shows no significant antagonistic activity against other LPA receptors (LPA1, LPA2, and LPA3). AS2717638 can be used in the research of pain and neuroinflammation-related diseases[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2148339-28-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114379.
AS2863619
AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241300-51-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126675A.
AS-35
AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation. Uses: As-35 is used as an antiallergic drug. Synonyms: AS 35; AS35; AS-35; 3-(1H-Tetrazol-5-yl)-9-[[[2-propyl-3-hydroxy-4-(methylcarbonyl)phenyl]oxy]methyl]-4H-pyrido[1,2-a]pyrimidin-4-one;AS35;4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-;9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one. Grades: >98%. CAS No. 108427-72-1. Molecular formula: C21H20N6O4. Mole weight: 420.42.
AS601245
AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 345987-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11010.
AS601245
AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. Synonyms: AS601245; AS-601245; AS 601245. Grades: >98%. CAS No. 345987-15-7. Molecular formula: C20H16N6S. Mole weight: 372.45.
AS601245
Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
AS-601811
AS-601811 is a 5-α reductase (type 1) inhibitor developed for the treatment of acne. Synonyms: 4,8-dimethyl-1,2,5,6-tetrahydrobenzo[f]quinolizin-3-one; AS-601811; AS 601811; AS601811; UNII-LIV8A6AE5F. Grades: >98%. CAS No. 194979-95-8. Molecular formula: C15H17NO. Mole weight: 227.307.
AS 602801
AS 602801 is a novel, orally active inhibitor of JNK. It blocked T-lymphocyte proliferation and induced apoptosis. Synonyms: AS602801; AS-602801; AS 602801; PGL5001; PGL-5001; PGL 5001; Bentamapimod. Grades: >98%. CAS No. 848344-36-5. Molecular formula: C25H23N5O2S. Mole weight: 457.55.
AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3K&alpha. Synonyms: AS604850; AS 604850; AS-604850. PI3K gamma inhibitor; PI 3-Kgamma Inhibitor II; (5E)-5-[(2,2-Difluoro-1,3-benzodioxol-5-YL)methylene]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 648449-76-7. Molecular formula: C11H5F2NO4S. Mole weight: 285.211.
AS 605240. Group: Biochemicals. Grades: Purified. CAS No. 648450-29-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AS-605240
AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis. Synonyms: AS 605240; AS605240; AS-605240. Grades: 0.98. CAS No. 648450-29-7. Molecular formula: C12H7N3O2S. Mole weight: 257.267.
AS-605240 potassium salt
Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer. AS-605240 inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively. AS-605240 also inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells with an IC50 value of 90 nM. AS-605240 potassium salt is the potassium salt form of AS-605240, which increase the water-solubility. Synonyms: AS-605240. Grades: ≥98%. Molecular formula: C12H6N3O2S·K. Mole weight: 295.4.
AS-703026
AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Group: Biochemicals. Alternative Names: N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide. Grades: Highly Purified. CAS No. 1236699-92-5. Pack Sizes: 25mg. US Biological Life Sciences.
AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC51355. CAS No. 796-42-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100744.
AS 8351
AS 8351 has been found to show the activity in inducing reprogramming of human fetal lung fibroblasts into functional cardiomyocytes. Synonyms: AS-8351; AS-8351; AS-8351; 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone. Grades: ≥98% by HPLC. CAS No. 796-42-9. Molecular formula: C17H13N3O2. Mole weight: 291.30.
AS-85
AS-85 is a potent ASH1L histone methyltransferase inhibitor ( IC 50 =0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the K d value of 0.78?μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2323623-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141430.
ASAFETIDA TINCTURE
ASAFETIDA TINCTURE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASAFETIDA TINCTURE;ASAFOETIDA OIL;FEMA 2108;Asafetida;asafoetida;Asafoetidagum;asant;asefetida. Product Category: Heterocyclic Organic Compound. CAS No. 9000-4-8. Product ID: ACM9000048. Alfa Chemistry ISO 9001:2015 Certified.
Asarinin
Asarinin. Group: Biochemicals. Alternative Names: (-)-Episesamin. Grades: Plant Grade. CAS No. 133-04-0. Pack Sizes: 20mg. Molecular Formula: C20H18O6, Molecular Weight: 354.353. US Biological Life Sciences.
Worldwide
Asarinin
Asarinin. Group: Biochemicals. CAS No. 133-04-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Asarone
Asarone. Group: Biochemicals. Grades: Plant Grade. CAS No. 2883-98-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Asarylaldehyde
Asarylaldehyde. Group: Biochemicals. Grades: Plant Grade. CAS No. 4460-86-0, 14374-62-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Asatone
Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 38451-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6826.
ASB 14-4
ASB 14-4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASB 14-4, ASB-14-4, Tetradecanoylamidopropyl-dimethylammonio-butanesulfonate, AGN-PC-015JOH, 4-[dimethyl-[3-(tetradecanoylamino)propyl]azaniumyl]butane-1-sulfonate, 4-{N,N-Dimethyl-N-[3-(tetradecanoylamino)propyl]ammonio}butanesulfonate, N,N-Dimethyl-N-[3-[(1-oxotetradecyl)amino]propyl]-4-sulfo1-butanaminium inner salt, 122398-33-8. Product Category: Heterocyclic Organic Compound. CAS No. 122398-33-8. Molecular formula: C23H48N2O4S. Mole weight: 448.7. Purity: 0.96. IUPACName: 4-[dimethyl-[3-(tetradecanoylamino)propyl]azaniumyl]butane-1-sulfonate. Canonical SMILES: CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CCCCS(=O)(=O)[O-]. Product ID: ACM122398338. Alfa Chemistry ISO 9001:2015 Certified.
ASB14780
ASB14780 is a potent and oral inhibitor of cytosolic phospholipase A2α (cPLA2α; IC50 = 0.020 μM in vitro and 0.54 - 0.64 μM in whole blood assay) with anti-inflammatory property in ear edema and asthma models. ASB14780 has the potential for the treatment of nonalcoholic fatty liver diseases including fatty liver and hepatic fibrosis. ASB14780 significantly attenuated expression of smooth muscle a-actin (a-SMA) protein and the mRNA expression of collagen 1a2, a-SMA and TGFb1 in the liver, as well as the expression of monocyte/macrophage markers. Synonyms: ASB14780; ASB 14780; ASB-14780; 3-(3-Phenethyl-1-(4-phenoxyphenyl)-1H-indol-5-yl)propanoic acid, 2-amino-2-(hydroxymethyl)-1,3-propanediol; 3-[1-(4-Phenoxyphenyl)-3-(2-phenylethyl)-1H-indol-5-yl]propanoic acid, 2-amino-2-(hydroxymethyl)-1,3-propanediol. Grades: 99%. CAS No. 1069046-00-9. Molecular formula: C31H27NO3.C4H11NO3. Mole weight: 582.69.
A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis. Group: Biochemicals. Grades: Highly Purified. CAS No. 52562-29-5. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Asbestos fibres in lung tissue (high content of amosite + crocidolite)
Ascalin is produced by Allium cepa var. aggregatum. It has antifungal activity against B.cinerea. Ascalin also inhibits HIV-1 reverse transcriptase with an IC50 of 10 μM.
Ascamycin
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. The MIC values of Ascamycin against Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei are 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL, respectively. Synonyms: (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine; 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine; 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine; 5'-O-{[(2S)-2-Amino-1-hydroxypropylidene]sulfamoyl}-2-chloroadenosine. Grades: ≥95%. CAS No. 91432-48-3. Molecular formula: C13H18ClN7O7S. Mole weight: 451.84.
Ascaphin-1
Ascaphin-1 is produced by Ascaphus truei. Ascaphin-1 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity.
Ascaphin-1M
Ascaphin-1M is produced by Alsodes montanus. It has antimicrobial activity.
Ascaphin-2
Ascaphin-2 is isolated from norepinephrine-stimulated skin secretions of A. truei and was shown to possess growth inhibitory activity against Escherichia coli and Staphylococcus aureus.
Ascaphin-3
Ascaphin-3 is produced by Ascaphus truei. Ascaphin-3 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity.
Ascaphin-3M
Ascaphin-3M is produced by Alsodes montanus. It has antimicrobial activity.
Ascaphin-4
Ascaphin-4 is produced by Ascaphus truei. Ascaphin-4 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity.
Ascaphin-4M
Ascaphin-4M is produced by Alsodes montanus. It has antimicrobial activity.
Ascaphin-5
Ascaphin-5 is produced by Ascaphus truei. Ascaphin-5 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity.
Ascaphin-5M
Ascaphin-5M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Synonyms: Gly-Ile-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Thr-Leu-Ile-Lys-Thr-Val-Ala-Ser-His-Ile-Ala-Asn-Gln. Grades: >98%. Molecular formula: C116H195N33O32. Mole weight: 2564.03.
Ascaphin-6
Ascaphin-6 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Synonyms: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Glu; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamic acid. Grades: >98%. CAS No. 722538-44-5. Molecular formula: C118H195N31O33. Mole weight: 2576.03.
Ascaphin-7
Ascaphin-7 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Synonyms: H-Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Gln-OH; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grades: ≥98%. CAS No. 722538-45-6. Molecular formula: C118H196N32O32. Mole weight: 2575.04.
Ascaphin-7M
Ascaphin-7M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Synonyms: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Ser-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Asn-Ile-Ala-Asn-Gln; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-seryl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-asparaginyl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grades: >98%. Molecular formula: C120H199N33O33. Mole weight: 2632.11.
Ascaphin-8
Ascaphin-8 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows similar potency against Gram-negative bacteria and Gram-positive bacteria and has a high hemolytic activity. Synonyms: Gly-Phe-Lys-Asp-Leu-Leu-Lys-Gly-Ala-Ala-Lys-Ala-Leu-Val-Lys-Thr-Val-Leu-Phe-NH2; glycyl-L-phenylalanyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-valyl-L-lysyl-L-threonyl-L-valyl-L-leucyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 722538-46-7. Molecular formula: C97H164N24O22. Mole weight: 2018.53.
Ascaridole
Ascaridole is an anthelmintic and also has antimalarial activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 512-85-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-118494.
Ascaridole
An organic peroxide which constitutes 60-80% of oil of chenopodium. Anthelmintic. Group: Biochemicals. Alternative Names: 1-Methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene. Grades: Highly Purified. CAS No. 512-85-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Asciminib
Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC 50 of 0.25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABL001. CAS No. 1492952-76-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010.
Asciminib
Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Uses: Tyrosine kinase inhibitors. Synonyms: ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide. CAS No. 1492952-76-7. Molecular formula: C20H18ClF2N5O3. Mole weight: 449.843.