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Azido-PEG2-alcohol is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG2-alcohol can be used in the synthesis of a series of PROTACs. Synonyms: 2-(2-azidoethoxy)ethanol; 2-(2-azidoethoxy)ethan-1-ol. Grades: >95%. CAS No. 139115-90-5. Molecular formula: C4H9N3O2. Mole weight: 131.13.
N3-PEG3-CH2COOH is a PROTAC linker, which refers to the alkyl/ether composition. N3-PEG3-CH2COOH can be used in the synthesis of a series of PROTACs. N3-PEG3-CH2COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Synonyms: Azido-PEG3-CH2CO2H;11-Azido-3,6,9-trioxaundecanoic Acid; N3-PEG3-CH2COOH; {2-[2-(2-Azidoethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; Azido-PEG3-CH2COOH. Grades: >95%. CAS No. 172531-37-2. Molecular formula: C8H15N3O5. Mole weight: 233.22.
Azido-PEG3-alcohol
Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Group: Azido peg linkers. Alternative Names: 1-Azido-8-hydroxy-3,6-dioxaoctane. CAS No. 86520-52-7. Molecular formula: C6H13N3O3. Mole weight: 175.19. Appearance: Oil. Purity: >90%. IUPACName: 2-[2-(2-Azidoethoxy)ethoxy]ethanol. Canonical SMILES: C(COCCOCCO)N=[N+]=[N-]. Catalog: ACM86520527.
Azido-PEG3-aldehyde
A heterobifunctional linker with alkyne and hydroxyamine/hydrazine reactivity. Synonyms: 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanal; N3-PEG3-pALD. Grades: >95%. Molecular formula: C16H22N4O5. Mole weight: 350.37.
Azido-PEG3-aldehyde
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Group: Other peg linkers. Alternative Names: N3-PEG3-CHO. CAS No. 1807530-10-4. Molecular formula: C9H17N3O4. Mole weight: 231.25. Appearance: Liquid. Purity: >90%. IUPACName: 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanal. Canonical SMILES: C(COCCOCCOCCN=[N+]=[N-])C=O. Catalog: ACM1807530104.
A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins. Synonyms: Azide-PEG4-Amine;1-Amino-11-azido-3,6,9-trioxaundecane; Amino-PEG3-C2-Azido; 1-[2-(2-aminoethoxy)ethoxy]-2-(2-azidoethoxy)ethane; N3-PEG3-CH2CH2NH2; Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; 11-Azido-3,6,9-trioxaundecan-1-amine; 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine. Grades: ≥95%. CAS No. 134179-38-7. Molecular formula: C8H18N4O3. Mole weight: 218.25.
N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units. N33-TEG-COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Synonyms: Azido-PEG4-CH2CO2H;Azido-PEG4-CH2COOH; N3-TEG-COOH; N3-PEG4-CH2COOH; 14-azido-3,6,9,12-tetraoxatetradecanoic acid; Acetic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-; 14-azido-3,6,9,12-tetraoxatetradecan-1-oic acid. Grades: ≥95%. CAS No. 201467-81-4. Molecular formula: C10H19N3O6. Mole weight: 277.27.
It is useful as a spacer and linker between compounds. Synonyms: Azido-PEG4-alcohol. Grades: ≥ 96 %. CAS No. 86770-67-4. Molecular formula: C8H17N3O4. Mole weight: 219.24.
Azido-PEG4-alcohol
Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Group: Azido peg linkers. Alternative Names: 11-Azido-3,6,9-trioxaundecanol. CAS No. 86770-67-4. Molecular formula: C8H17N3O4. Mole weight: 219.24. Appearance: Oil. Purity: >90%. IUPACName: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCO)N=[N+]=[N-]. Catalog: ACM86770674.
N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Synonyms: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31.
Azido-PEG4-azide
Azido PEG Linkers. CAS No. 101187-39-7. Molecular formula: C8H16N6O3. Mole weight: 244.25. Purity: 95%+. Catalog: ACM101187397.
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG4-C2-NHS ester. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2- (2-azidoethoxy) ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM944251245.
Azido-PEG4-NHS-ester
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807534-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140765.
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Group: Azido peg linkers. Alternative Names: 1-Azidohexaethylene glycol. CAS No. 86770-68-5. Molecular formula: C10H21N3O5. Mole weight: 263.29. Appearance: Oil. Purity: >90%. IUPACName: 2-[2-[2-[2- (2-Azidoethoxy) ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCO)N=[N+]=[N-]. Catalog: ACM86770685.
Azido-PEG5-amine
Azido-PEG5-amine is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG5-amine can be used in the synthesis of a series of PROTACs. Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)tetraethylene Glycol; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine; N3-PEG5-CH2CH2NH2; N3-PEG5-NH2; 1-Amino-17-azido-3,6,9,12,15-pentaoxaheptadecane; 17-Azido-3,6,9,12,15-pentaoxaheptadecanamine. Grades: ≥95%. CAS No. 516493-93-9. Molecular formula: C12H26N4O5. Mole weight: 306.36.
Azido-PEG5-azide
Azido-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG5-azide can be used in the synthesis of a series of PROTACs. Uses: A cross-linking reagent. Synonyms: 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE. Grades: >95%. CAS No. 356046-26-9. Molecular formula: C12H24N6O5. Mole weight: 332.36.
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Group: Azido peg linkers. Alternative Names: N3-PEG5-SPA. CAS No. 1433996-86-1. Molecular formula: C17H28N4O9. Mole weight: 432.4. Appearance: Liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3- [2- [2- [2- [2- (2-azidoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM1433996861.
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG6-OH. CAS No. 86770-69-6. Molecular formula: C12H25N3O6. Mole weight: 307.34. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (2-Azidoethoxy) ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N=[N+]=[N-]. Catalog: ACM86770696.
O-(2-Azidoethyl)heptaethylene glycol (CAS# 352439-36-2) is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery. Uses: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. in the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. monodisperse azide-peg8-alcohol (n3-peg8-oh) is a click chemistry reagent with an azide(n3) and a terminal hydroxyl (oh) group. the azide group is reactive with alkyne, bcn, dbco via click chemistry to yield a stable triazole linkage. the hydroxyl (oh) group enables further derivatization or replacement with other functional groups. Synonyms: N3-PEG8-OH; Azide-PEG8-alcohol; 2- [2- [2- [2- [2- [2- [2- (2-azidoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol. Grades: >97%. CAS No. 352439-36-2. Molecular formula: C16H33N3O8. Mole weight: 395.45.
Azido-PEG8-amine
Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine. Grades: ≥90%. CAS No. 857891-82-8. Molecular formula: C18H38N4O8. Mole weight: 438.52.
Azido-PEG9-alcohol is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG9-alcohol can be used in the synthesis of a series of PROTACs. Synonyms: N3-PEG9-OH. Grades: >97%. CAS No. 1984776-37-5. Molecular formula: C18H37N3O9. Mole weight: 439.50.