A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Double-Walled Carbon Nanotubes (DWNTs) 2-4nm. Uses: Double-walled carbon nanotubes (cnts) can be used in various fields including additives in polymers, catalysts, electron field emitters for cathode ray lighting elements, flat panel display, gas-discharge tubes in telecom networks, electromagnetic-wave absorption and shielding, energy conversion, lithium-battery anodes, hydrogen storage, nanotube composites (by filling or coating); nanoprobes for stm, afm, and efm tips, nanolithography, nanoelectrodes, drug delivery sensors, reinforcements in composites, supercapacitor. Additional or Alternative Names: Double-Walled Carbon Nanotubes, Double Wall Carbon Nanotube, Carbon Nanotube, DWNT, DWCNT, CNT. Product Category: Carbon Nanotubes. Appearance: Color: Black. CAS No. 1333-86-4. Purity: >60%. Density: True density: ~2.1 g/cm³. Product ID: ACM1333864-32. Alfa Chemistry ISO 9001:2015 Certified.
DOV-216,303 (Free Base) is a potent triple serotonin , norepinephrine , and dopamine reuptake inhibitor, with IC 50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively [1]. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66504-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18332C.
Dovitinib
Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5, 10, 8, 27, 36 nM respectively. Dovitinib selectively blocked the growth of wild-type (WT) or activated mutant FGFR3-transformed B9 cells and human myeloma cell lines. Dovitinib was an effective treatment in a xenograft mouse model of FGFR3 multiple myeloma. Synonyms: Dovitinib, TKI258; TKI 258;TKI-258; CHIR 265; CHIR265; CHIR-265; RAF-265; RAF 265; RAF265. Grades: > 95%. CAS No. 405169-16-6. Molecular formula: C21H21FN6O. Mole weight: 392.429.
Dovitinib
Dovitinib (CHIR-258) is an orally active, potent multi-targeted tyrosine kinase (RTK) inhibitor with IC 50 s of 1, 2, 36, 8/9, 10/13/8, 27/210 nM for FLT3 , c-Kit , CSF-1R , FGFR1/FGFR3 , VEGFR1/VEGFR2/VEGFR3 and PDGFRα/PDGFRβ , respectively. Dovitinib has potent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHIR-258; TKI258. CAS No. 405169-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50905.
Dovitinib Dilactic Acid
Dovitinib is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Synonyms: Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258; CHIR 258; CHIR258; TKI258; TKI 258; TKI-258. Grades: >98%. CAS No. 852433-84-2. Molecular formula: C27H33FN6O7. Mole weight: 572.59.
Dovitinib lactate
Dovitinib lactate (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC 50 s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3 , c-Kit , FGFR1/3 , VEGFR1/2/3 and PDGFRα/β , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHIR-258 lactate; TKI-258 lactate. CAS No. 692737-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10207.
Dovitinib lactate
Dovitinib, also referred as CHIR-258 or TKI258, is a potent receptor tyrosine kinase inhibitor (TKI) that selectively targets VEGFR, PDGFR, FGFR, CSF1R, c-KIT, RET, TrKA, and FLT3, and additionally targets FGFR (IC50 = 5 nM). Synonyms: 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1,3-dihydrobenzimidazol-2-ylidene]quinolin-2-one;2-hydroxypropanoic acid; 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate; Dovitinib(lactate); 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxy; CTK8B6779. CAS No. 692737-80-7. Molecular formula: C24H27FN6O4. Mole weight: 482.51.
Dovitinib Lactate
Dovitinib is used in treating melanoma. Group: Biochemicals. Alternative Names: 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-Hydroxypropanoic Acid; CHIR 258; TKI 258. Grades: Highly Purified. CAS No. 692737-80-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dovitinib Lactate Hydrate
Dovitinib lactate hydrate is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively. Synonyms: TKI258 lactate hydrate; CHIR-258 lactate hydrate; 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrate; Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone, hydrate (1:1:1). Grades: >98%. CAS No. 915769-50-5. Molecular formula: C24H29FN6O5. Mole weight: 500.52.
Dov-Val-Dil-OH
Dov-Val-Dil-OH is an intermediate of dolastoxin, a cytotoxic liner peptide produced by Dolabbella auriclaria which exhibits potent antitumor activity. Synonyms: (3R,4S,5S)-4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoic acid; (3R,4S,5S)-3-Methoxy-4-[methyl(N,N-dimethyl-L-Val-L-Val-)amino]-5-methylheptanoic acid. CAS No. 133120-89-5. Molecular formula: C22H43N3O5. Mole weight: 429.59.
Dov-Val-Dil-OH TFA
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dov-Val-Dil-OH TFA; Dov-Val-Dil-OH; Dov-Val-Dil-OH; dimethylVal-Val-Dil-COOH. Product Category: Others. Appearance: Solid powder. CAS No. 133120-90-8. Molecular formula: C24H44F3N3O7. Mole weight: 543.63. Purity: >98%. IUPACName: (3R,4S,5S)-4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoic acid trifluoroacetic acid. Canonical SMILES: CC[C@H](C)[C@H](N(C)C([C@@H](NC([C@@H](N(C)C)C(C)C)=O)C(C)C)=O)[C@H](OC)CC(O)=O.O=C(O)C(F)(F)F. Product ID: ACM133120908. Alfa Chemistry ISO 9001:2015 Certified.
Dowicil 200 (Quaternium-15) is a skin toxin and allergen that inhibits the growth of Pinctada fucata cells. Dowicil 200 has antimicrobial activity and is more potent against fungi and molds than against fungi. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Quaternium-15. CAS No. 51229-78-8. Pack Sizes: 10 mM * 1 mL; 250 mg. Product ID: HY-W009497.
Doxacurium Chloride (Mixture of Diastereomers)
Doxacurium Chloride is a nondepolarizing neuromuscular blocking agent that is minimally hydrolyzed by human plasma cholinesterase. Group: Biochemicals. Grades: Highly Purified. CAS No. 106819-53-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C56H78Cl2N2O16, Molecular Weight: 1106.13. US Biological Life Sciences.
Worldwide
Doxapram
Doxapram is a respiratory stimulant with analeptic activity. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate. Doxapram stimulates chemoreceptors in the carotid bodies of the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem. It has been used as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease. Uses: Central nervous system stimulants; respiratory system agents. Synonyms: Dopram; 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one; Doxapramum; AHR-619; AHR 619; AHR619. Grades: ≥98%. CAS No. 309-29-5. Molecular formula: C24H30N2O2. Mole weight: 378.51.
Doxapram
Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 309-29-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-B0551.
Doxapram EP Impurity B
Doxapram EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-ethyl-4-(2-((2-hydroxyethyl)amino)ethyl)-3,3-diphenylpyrrolidin-2-one. CAS No. 1688-76-2. Molecular formula: C22H28N2O2. Mole weight: 352.47. Catalog: APB1688762.
Doxazosin (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Uses: Scientific research. Group: Natural products. Alternative Names: UK 33274. CAS No. 74191-85-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0098.
Doxazosin
Doxazosin is a quinazoline-derivative and long-lasting α1 adrenergic receptor blocker. It inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. It is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms. It may have an inhibitory effect on cholesterol synthesis independent of the LDL receptor. It also shows high affinity to alpha-1c adrenoceptor which may partially attribute to its effect in treatment of benign prostatic hyperplasia. It has been found to help reduce the intensity of and/or stop posttraumatic stress disorder night terrors and nightmares. Synonyms: [4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-(2,5-dioxabi cyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone; Piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-; UK 33274; Doxazosin; Cardura; Alfamedin. Grades: 98%. CAS No. 74191-85-8. Molecular formula: C23H25N5O5. Mole weight: 451.48.
Doxazosin-d8
Labeled Doxazosin, a selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Doxazosin EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(piperazine-1,4-diyl)bis(6,7-dimethoxyquinazolin-4-amine). CAS No. 102839-00-9. Molecular formula: C24H28N8O4. Mole weight: 492.53. Catalog: APB102839009.
Doxazosin Impurity 10
Doxazosin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(6-hydroxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone. CAS No. 102932-28-5. Molecular formula: C23H25N5O6. Mole weight: 467.47. Catalog: APB102932285.
Doxazosin Impurity 9
Doxazosin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(4-amino-6-hydroxy-7-methoxyquinazolin-2-yl)piperazin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone. CAS No. 102932-26-3. Molecular formula: C22H23N5O5. Mole weight: 437.45. Catalog: APB102932263.
Doxazosin mesilate
Doxazosin mesilate. Group: Biochemicals. Alternative Names: UK-33274-27; Alfadil; Cardenalin. Grades: Highly Purified. CAS No. 77883-43-3. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C24H29N5O8S. US Biological Life Sciences.
Worldwide
Doxazosin mesylate
Doxazosin mesylate (UK 33274 mesylate) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 33274 mesylate. CAS No. 77883-43-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0098A.
Doxazosin mesylate
Doxazosin mesylate. Group: Biochemicals. Grades: Purified. CAS No. 77883-43-3. Pack Sizes: 50mg. US Biological Life Sciences.
Doxazosin mesylate is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. Grades: >98%. CAS No. 77883-43-3. Molecular formula: C24H29N5O8S. Mole weight: 547.58.
A selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: UK-33274-27, Alfadil, Cardenalin. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsan and skeletal muscle relaxant properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAS-643. CAS No. 40762-15-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101808.
Doxepin
Doxepin is a tricyclic antidepressant. Uses: Adrenergic uptake inhibitors; anti-anxiety agents; antidepressive agents, tricyclic; antipruritics. Synonyms: (E/Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine. Grades: > 95%. CAS No. 1668-19-5. Molecular formula: C19H21NO. Mole weight: 279.38.
Doxepin-13C3
Doxepin-13C3 is a derivative of Doxepin Hydrochloride (D550000), which is used clinically to treat anxiety and depression. Doxepin is an antidepressant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1613C3H21NO, Molecular Weight: 282.35. US Biological Life Sciences.
Worldwide
Doxepin D3 Hydrochloride
Doxepin-d 3 (hydrochloride) is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347840-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0725S.
Doxepin EP Impurity B
An impurity in the synthesis of Doxepin. Synonyms: (11RS)-11-[3-(Dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol. Grades: > 95%. CAS No. 4504-88-5. Molecular formula: C19H23NO2. Mole weight: 297.39.
Doxepin HCL USP
Doxepin HCL USP.
CA, FL & NJ
Doxepin hydrochloride
Doxepin hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1229-29-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Doxepin Hydrochloride
Highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant. Also binds to the H4 histamine receptor (pKi = 6.79). Synonyms: Sinequan; Adapin; Silenor. Grades: >98%. CAS No. 1229-29-4. Molecular formula: C19H22ClNO. Mole weight: 315.84.
Doxepin Hydrochloride
Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 [1] [2]. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant [3]. Doxepin has therapeutic effects in atopic dermatitis, chronic urticarial, can improve cognitive processes, protect central nervous system [4]. Doxepin has also been proposed as a protective factor against oxidative stress [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1229-29-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0725.
Used clinically to treat anxiety and depression. Group: Biochemicals. Alternative Names: 11- (3-Dimethylaminopropyl idene) -6, 11-dihydrodibenz [b, e] oxepin, Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Doxepin-N- β-D-Glucuronide
Doxepin-N- β-D-Glucuronide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1075185-73-7. Pack Sizes: 5mg. Molecular Formula: C25H29NO7, Molecular Weight: 455.5. US Biological Life Sciences.
Worldwide
Doxepin-N- β-D-Glucuronide-d3
Doxepin-N- β-D-Glucuronide-d3. Group: Biochemicals. Alternative Names: 3-Dibenz[b,e]oxepin-11(5H)-ylidene-N- β-D-glucopyranuronosyl-N,N-dimethyl-(3Z)-1-propanaminium-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H26D3NO7, Molecular Weight: 458.52. US Biological Life Sciences.
Worldwide
Doxepin N-Oxide
Doxepin N-Oxide is a metabolite of Doxepin. Group: Biochemicals. Alternative Names: 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine. Grades: Highly Purified. CAS No. 22684-91-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Doxepin related compound A
Doxepin intermediate. A photodecomposition product of Doxepin. Synonyms: 6,11-Dihydrodibenz[b,e]oxepin-11-one; Dibenz[b,e]oxepin-11(6H)-one. Grades: > 95%. CAS No. 4504-87-4. Molecular formula: C14H10O2. Mole weight: 210.23.
Doxercalciferol. Group: Biochemicals. Grades: Purified. CAS No. 54573-75-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Doxercalciferol
Doxercalciferol (Hectorol; 1.alpha.-Hydroxyvitamin D2) is a synthetic analog of vitamin D; is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). Synonyms: Hectorol; 1.alpha.-Hydroxyvitamin D2. Grades: 0.98. CAS No. 54573-75-0. Molecular formula: C28H44O2. Mole weight: 412.65.
Doxercalciferol
Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor , and prevent renal disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1.alpha.-Hydroxyvitamin D2. CAS No. 54573-75-0. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32348.
Doxercalciferol
?98% (HPLC), solubility: >10 mg/mL in DMSO. Group: Fluorescence/luminescence spectroscopy.
Doxifluridine
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 21-9738; 5-Fluoro-5'-deoxyuridine; 5'-DFUR. CAS No. 3094-9-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0021.
A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity. Group: Biochemicals. Alternative Names: 5-Deoxy-5-fluorouridine, 5-DFUR, 5-dFUrd, Ro-21-9738. Grades: Highly Purified. CAS No. 3094-9-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
D-Oxime Ribose
D-Oxime Ribose is a D-Ribose derivative, and it is useful in the synthesis of riboflavin derivatives. Synonyms: Oxime Ribose; NSC 37845. CAS No. 6272-50-0. Molecular formula: C5H11NO5. Mole weight: 165.14.