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| Product | Description | |
|---|---|---|
| Dosulepin Impurity C | Dothiepin intermediate. Synonyms: 11-[3-(Dimethylamino)propyl]-6,11-dihydro-dibenzo[b,e]thiepin-11-ol; 6,11-Dihydro-11-hydroxy Dothiepin. Grade: > 95%. CAS No. 1531-85-7. Molecular formula: C19H23NOS. Mole weight: 313.47. |  |
| Dosulepin Impurity E | Dothiepin impurity. Synonyms: (E)-3-(5,5-Dioxidodibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine; (E)-3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine S,S-Dioxide; (E)-11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]thiepine 5,5-Dioxide. Grade: > 95%. CAS No. 25846-81-5. Molecular formula: C19H21NO2S. Mole weight: 327.44. | |
| Dosulepin Sulfone | Dosulepin Sulfone is a pharmacological agent employed within the research of the symptoms associated with melancholic states and sundry afflictions of emotional disposition. Synonyms: 33301-24-5; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepine-5,5-dioxide(3E)-3-(5,5-dioxo-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amineDibenzo(b,e)thiepin-delta(sup 11(6H)),gamma-propylamine, N,N-dimethyl-, 5,5-dioxide; ZINC346580. Grade: > 95%. CAS No. 33301-24-5. Molecular formula: C19H21NO2S. Mole weight: 327.45. | |
| Dot | Dot - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Dot1L human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| Dot1L-IN-1 | Dot1L-IN-1 is a selective and highly potent Dot1L inhibitor with a Ki of 2 pM. Synonyms: N2-{[2-Chloro-3-(2-methyl-3-pyridinyl)-1-benzothiophen-5-yl]carbamoyl}-N-(3-{methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino}propyl)glycinamide; Acetamide, 2-[[[[2-chloro-3-(2-methyl-3-pyridinyl)benzo[b]thien-5-yl]amino]carbonyl]amino]-N-[3-[methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino]propyl]-. Grade: ≥95%. CAS No. 2088518-50-5. Molecular formula: C32H36ClN9O2S. Mole weight: 646.21. | |
| Dot1L-IN-2 | Dot1L-IN-2 is a potent, selective and orally bioavailable Dot1L (a histone methyltransferase) inhibitor, with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively. Synonyms: 2,4-Pyrimidinediamine, N4-methyl-N2-[2-methyl-1-[2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl]-1H-indol-6-yl]-; N4-Methyl-N2-(2-methyl-1-{2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl}-1H-indol-6-yl)-2,4-pyrimidinediamine. Grade: ≥95%. CAS No. 1940206-71-2. Molecular formula: C27H24N8O. Mole weight: 476.53. | |
| Dot1L-IN-4 | Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.11 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2565705-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135127. |  |
| Dot1L-IN-4 | Dot1L-IN-4 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.11 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-1,2-benzenediamine. Grade: ≥95%. CAS No. 2565705-02-2. Molecular formula: C28H27ClF2N8O5S. Mole weight: 661.08. | |
| Dot1L-IN-5 | Dot1L-IN-5 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.17 nM. Synonyms: Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]-; 3-[(4-Amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-{[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino}benzenesulfonamide. CAS No. 2565705-03-3. Molecular formula: C23H19ClF2N8O5S. Mole weight: 592.96. | |
| Dot1L-IN-6 | Dot1L-IN-6 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.19 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-1,2-benzenediamine. CAS No. 2565705-01-1. Molecular formula: C25H21ClF2N6O6S. Mole weight: 606.99. | |
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. |  Worldwide |
| DOTA(allyl ester)3 | DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61. | |
| DOTA-Biotin-Sarcosine | DOTA-Biotin-Sarcosine. Synonyms: [3aS-[3aα,4β(R*),6aα]]-2-[[4-[[[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]methylamino]acetyl]amino]phenyl]methyl]-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid. CAS No. 180978-54-5. Molecular formula: C36H54N8O11S. Mole weight: 806.93. | |
| DOTA derivative | DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: DOTA derivative. Grade: >98%. CAS No. 153777-70-9. Molecular formula: C43H50N4O8S4. Mole weight: 879.14. | |
| DOTA-Lanreotide | An impurity of Lanreotide. Lanreotide is a synthetic somatostatin analogue used primarily to treat conditions related to excessive hormone production, such as acromegaly and neuroendocrine tumors. Synonyms: L-Threoninamide, 3-(2-naphthalenyl)-N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-BIM 23014; DOTA-LAN; DOTA-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); DOTA-3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grade: ≥95%. CAS No. 213187-44-1. Molecular formula: C70H95N15O17S2. Mole weight: 1482.73. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Synonyms: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126. | |
| DOTA-NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170908-81-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128890. DOTA-?NHS-ester | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grade: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTAP chloride | ?98% (TLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A. | |
| DOTAP:Chol (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| DOTAP:Chol:DOPE (10:75:5) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:Chol:PEG2000 (65:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (1:99)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (20:80)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (5:95)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (10:55:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (1:64:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (20:45:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (2.5:62.5:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (30:35:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (40:25:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (50:15:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (5:60:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (60:5:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPE (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. DOTA-PEG5-azide can be used in the synthesis of a series of PROTACs. Synonyms: DOTA-PEG5-C2-azide. Grade: 95%. Molecular formula: C28H52N8O12. Mole weight: 692.76. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140752. | |
| DOTA-PEG5-C6-DBCO | DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-140314. | |
| DOTAP Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP mesylate | DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 252769-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W127426. | |
| DOTAP methylsulfate | DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate. CAS No. 144189-73-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-W127378. | |
| DOTAP:PC:Chol (10:60:30)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Dotarizine | Dotarizine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C29H34N2O2. US Biological Life Sciences. | Worldwide |
| Dotarizine (1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine, FI-6026) | Antimigraine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| DOTATATE | DOTATATE is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-octreotate; DOTA-TATE; DOTA-[Tyr3]-Octreotide Acid; DOTA-(Tyr3)-octreotate. Grade: ≥95%. CAS No. 177943-88-3. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63. | |
| DOTATATE | DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106244. | |
| DOTATATE acetate | DOTATATE acetate is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE acetate is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate (salt) (1:x); DOTA-(Tyr3,Thr8)-Octreotide acetate; DOTA-[Tyr3] Octreotide Acid (Octreotate) acetate; DOTA-octreotate acetate; DOTA-[Tyr3]-Octreotide Acid acetate. Grade: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2.xC2H4O2. Mole weight: 1435.63 (free base). | |
| DOTATATE acetate | DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106244A. | |
| DOTA (TETRAXETAN) | Tetraxetan is a biochemical reagent that can be used as a biological material or organic compound for life science related research. CAS No. 60239-18-1. Product ID: API60239181. SMILES: C1CN(CCN(CCN(CCN1CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O. Appearance: white powder. Category: Active Pharmaceutical Ingredients. |  |
| DOTA-tris(tBu)ester NHS ester | DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 819869-77-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-131326. | |
| DOTA-tris(tert-butyl ester) | It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; DOTA tri(tert-butyl) ester; DOTA(OBu-t)3; Tri-tert-Bu-DOTA; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA(OtBu); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-tris-tert-butyl acetate-10-acetic acid. Grade: 95%. CAS No. 137076-54-1. Molecular formula: C28H52N4O8. Mole weight: 572.73. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester) can be used in the synthesis of generations 3 (G3) nanoglobular magnetic resonance imaging (MRI) contrast agents for MR angiography and tumor angiogenesis imaging [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 137076-54-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W034551. | |
| Dotetracontane | analytical standard. Group: Fuels and hydrocarbons. | |
| Dothiepin | A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-. Grades: Highly Purified. CAS No. 113-53-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dothiepin | Dothiepin (Dosulepin; Dothep) is an antidepressant agent with sedative/anxiolytic activity. Dothiepin is an inhibitor preferring of noradrenaline uptake than serotonin uptake. Dothiepin facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. Dothiepin is also an antagonist of histamine H1-receptor without cardiotoxicity. Dothiepin exhibits significant analgesic activity in psychogenic facial pain, idiopathic fibromyalgia syndrome or rheumatoid arthritis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dosulepin; Dothep. CAS No. 113-53-1. Pack Sizes: 1 mg. Product ID: HY-12394. | |
| Dothiepin-d3 | Labeled Dothiepin. A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-. Grades: Highly Purified. CAS No. 136765-31-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Dothiepin-[d3] | Dothiepin-[d3] is the labelled analogue of Dothiepin, which is a tricyclic antidepressant. Synonyms: Dothiepin D3; 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-1-propanamine; N,N-(Dimethyl-d3)-dibenzo[b,e]thiepin-11(6H), γ-propylamine-d3; Dosulepin-d3; Dosulepine-d3; Dothep-d3; Prothiaden-d3; Prothiadene-d3; cis-dothiepin-d3; Z-dothiepin-d3. Grade: ≥95%; ≥98% atom D. CAS No. 136765-31-6. Molecular formula: C19H18D3NS. Mole weight: 298.46. | |
| Dothiepin-[d3] Maleate | Dothiepin-[d3] Maleate is the labelled analogue of dothiepin. Dothiepin is a tricyclic antidepressant which is used in the treatment of depression. Synonyms: Dothiepin-d3 Maleate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C23H22D3NO4S. Mole weight: 414.53. | |
| Dothiepin-[d6] HCl (N,N-dimethyl-[d6]) (cis/trans mixture) | Dothiepin-[d6] HCl is an isotope labelled form of Dothiepin hydrochloride. Dosulepin is a tricyclic antidepressant which is used in the treatment of depression. Synonyms: Dosulepin HCl; 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine HCl. Grade: 95%+ by HPLC; 99% atom D. CAS No. 1276545-35-7. Molecular formula: C19H16D6ClNS. Mole weight: 337.94. | |
| Dotinurad | Dotinurad. Alternative Names: FYU-981. Dotinurad [INN]. (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone. CAS No. 1285572-51-1. Product ID: API1285572511. Molecular formula: C14H9Cl2NO4S. Mole weight: 358.2. SMILES: C1N(C2=CC=CC=C2S1(=O)=O)C(=O)C3=CC(=C(C(=C3)Cl)O)Cl. Category: Anti-Gout APIs. | |
| DOTMA | DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 104872-42-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-139200. | |
| DOTMA | DOTMA is one of the first cationic lipid used for gene transfection. DOTMA is an effective transfection agent in vitro and in vivo. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DOTMA; 1,2-di-O-octadecenyl-3-trimethylammonium propane. Product Category: Others. Appearance: Solid powder. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.59. Purity: >98%. IUPACName: N,N,N-trimethyl-2,3-bis(((Z)-octadec-9-en-1-yl)oxy)propan-1-aminium chloride. Canonical SMILES: CCCCCCCC/C=C\CCCCCCCCOCC(OCCCCCCCC/C=C\CCCCCCCC)C[N+](C)(C)C.[Cl-]. Product ID: ACM104872426. Alfa Chemistry ISO 9001:2015 Certified. |  |
| DOTMA | DOTMA is one of the first cationic lipid used for gene transfection. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Synonyms: 1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium. Grade: >98%. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.57. | |
| DOTMA:Chol (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTMA:DOPE (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTMA Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Dotriacolide | It is produced by the strain of Micromonosporaechinospora MG199-fF35. It has inhibitory effects on β-lactamase, DNA enzyme and Topoisomerase I. Synonyms: Oxacyclodotriacont-3-en-2-one,16,18,30-tris(sulfooxy)-32-(8-(sulfooxy)nonyl)-; (Z)-32-oxo-2-(8-(sulfooxy)nonyl)oxacyclodotriacont-30-ene-4,16,18-triyl tris(hydrogen sulfate). CAS No. 80994-06-5. Molecular formula: C40H76O18S4. Mole weight: 973.28. | |
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