A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Doxazosin mesylate (UK 33274 mesylate) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 33274 mesylate. CAS No. 77883-43-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0098A.
Doxazosin mesylate
Doxazosin mesylate. Group: Biochemicals. Grades: Purified. CAS No. 77883-43-3. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Doxazosin Mesylate
Doxazosin mesylate is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. Grade: 98%. CAS No. 77883-43-3. Molecular formula: C24H29N5O8S. Mole weight: 547.58.
Doxazosin Mesylate
Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance. Alternative Names: Doxazosin mesylate. Cardura. Carduran. Cardular. CAS No. 77883-43-3. Product ID: API77883433. Molecular formula: C24H29N5O8S. Mole weight: 547.6. EINECS: 616-536-9. SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O. Category: Cardiovascular and Geriatric Medicine APIs.
A selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: UK-33274-27, Alfadil, Cardenalin. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Doxefazepam
Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsan and skeletal muscle relaxant properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAS-643. CAS No. 40762-15-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101808.
Doxepin-13C3
Doxepin-13C3 is a derivative of Doxepin Hydrochloride (D550000), which is used clinically to treat anxiety and depression. Doxepin is an antidepressant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1613C3H21NO, Molecular Weight: 282.35. US Biological Life Sciences.
Worldwide
Doxepin D3 Hydrochloride
Doxepin-d 3 (hydrochloride) is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347840-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0725S.
Doxepin HCL USP
Doxepin HCL USP.
CA, FL & NJ
Doxepin hydrochloride
Doxepin hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1229-29-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Doxepin Hydrochloride
Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 [1] [2]. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant [3]. Doxepin has therapeutic effects in atopic dermatitis, chronic urticarial, can improve cognitive processes, protect central nervous system [4]. Doxepin has also been proposed as a protective factor against oxidative stress [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1229-29-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0725.
Used clinically to treat anxiety and depression. Group: Biochemicals. Alternative Names: 11- (3-Dimethylaminopropyl idene) -6, 11-dihydrodibenz [b, e] oxepin, Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Doxepin-N- β-D-Glucuronide
Doxepin-N- β-D-Glucuronide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1075185-73-7. Pack Sizes: 5mg. Molecular Formula: C25H29NO7, Molecular Weight: 455.5. US Biological Life Sciences.
Worldwide
Doxepin-N- β-D-Glucuronide-d3
Doxepin-N- β-D-Glucuronide-d3. Group: Biochemicals. Alternative Names: 3-Dibenz[b,e]oxepin-11(5H)-ylidene-N- β-D-glucopyranuronosyl-N,N-dimethyl-(3Z)-1-propanaminium-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H26D3NO7, Molecular Weight: 458.52. US Biological Life Sciences.
Worldwide
Doxepin N-Oxide
Doxepin N-Oxide is a metabolite of Doxepin. Group: Biochemicals. Alternative Names: 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine. Grades: Highly Purified. CAS No. 22684-91-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Doxercalciferol
Doxercalciferol is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). Synonyms: Hectorol; 1-Hydroxyergocalciferol; 1alpha-Hydroxyergocalciferol; 1-alpha-Hydroxyvitamin D2. Grade: 98%. CAS No. 54573-75-0. Molecular formula: C28H44O2. Mole weight: 412.65.
Doxercalciferol
Doxercalciferol. Group: Biochemicals. Grades: Purified. CAS No. 54573-75-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Doxercalciferol
Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor , and prevent renal disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1.alpha.-Hydroxyvitamin D2. CAS No. 54573-75-0. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32348.
Doxercalciferol
?98% (HPLC), solubility: >10 mg/mL in DMSO. Group: Fluorescence/luminescence spectroscopy.
Doxercalciferol-13C-d3
One of the isotopic labelled impurities of Vitamin D2, which could be effective as an antirachitic agent. Synonyms: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E)-1,4,5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol-13C-d3. Molecular formula: C27[13C]H41O2. Mole weight: 416.67.
Doxercalciferol-[d3]
One of the isotopic labelled impurities of Vitamin D2, which could be effective as an antirachitic agent. Synonyms: (1α,3β,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol-d3; 1-Hydroxyergocalciferol-d3; 1-Hydroxyvitamin D2-d3; Doxercalciferol D3. Grade: >98%. CAS No. 2070009-32-2. Molecular formula: C28H41D3O2. Mole weight: 415.66.
Doxifluridine
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 21-9738; 5-Fluoro-5'-deoxyuridine; 5'-DFUR. CAS No. 3094-9-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0021.
Doxifluridine
Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. Uses: Antimetabolites, antineoplastic. Synonyms: Doxifluridine; 5'-deoxy-5-fluorouridine; Furtulon; Flutron; doxyfluridine; 5'-Doxifluridine; 5-Fluorodeoxyuridine; USP Capecitabine Related Compound B; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil. Grade: ≥95%. CAS No. 3094-9-5. Molecular formula: C9H11FN2O5. Mole weight: 246.194.
A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity. Group: Biochemicals. Alternative Names: 5-Deoxy-5-fluorouridine, 5-DFUR, 5-dFUrd, Ro-21-9738. Grades: Highly Purified. CAS No. 3094-9-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
D-Oxime Ribose
D-Oxime Ribose is a D-Ribose derivative, and it is useful in the synthesis of riboflavin derivatives. Synonyms: Oxime Ribose; NSC 37845; D-Ribose, oxime; D-Ribose oxime. CAS No. 6272-50-0. Molecular formula: C5H11NO5. Mole weight: 165.14.
DOXO-EMCH
DOXO-EMCH is an albumin-binding prodrug of doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Uses: Adcs cytotoxin-linker. Synonyms: 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, [1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide; 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, [1-[4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide, (2S-cis)-; Doxorubicin-EMCH. Grade: >98%. CAS No. 151038-96-9. Molecular formula: C37H42N4O13. Mole weight: 750.75.
Doxofylline
Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways ( NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 69975-86-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0004.
?98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 69975-86-6. Pack Sizes: 50MG. Mole weight: 266.25. Catalog: AP69975866. Assay: ?98% (HPLC).
Doxofylline
5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C11H14N4O4. CAS No. 69975-86-6. Prepack ID 64180970-5g. Molecular Weight 266.25. See USA prepack pricing.
Doxofylline
It has a role as a bronchodilator agent, an antitussive and an anti-asthmatic drug. Alternative Names: Doxophylline. Ansimar. Dioxyfilline. CAS No. 69975-86-6. Product ID: API69975866. Molecular formula: C11H14N4O4. Mole weight: 266.25. EINECS: 274-239-6. SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3. Appearance: Crystals. Category: Antiasthmatic APIs.
Doxofylline
Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Uses: Antitussive agents. Synonyms: Doxofylline; Ansimar; ABC-12-3; ABC-1213; ALT-07; DO-309; ABC 12 3; ABC 1213; ALT 07; DO 309; ABC12; 3; ABC1213; ALT07; DO309. Grade: >98%. CAS No. 69975-86-6. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Doxofylline.
Doxofylline. Group: Biochemicals. Alternative Names: 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 7-[1, 3- (Dioxolan-d4) -2-ylmethyl) ]theophylline; 2-(7'-Theophyllinemethyl)-1,3-dioxolane; ABC 12/3; ABC 1213; Ansimar; Dioxyfilline; Doxophylline; Maxivent; Ventax. Grades: Highly Purified. CAS No. 69975-86-6. Pack Sizes: 5g. Molecular Formula: C11H14N4O4, Molecular Weight: 266.25. US Biological Life Sciences.
Worldwide
Doxofylline-[d6]
Doxofylline-[d6] is an isotope labelled doxofylline. Doxofylline is a xanthine derivative drug used to treat asthma. Synonyms: Doxofylline D6; 7-(1,3-Dioxolan-2-ylmethyl)-1,3-bis[(2H3)methyl]-3,7-dihydro-1H-purine-2,6-dione. Grade: 95%+ by HPLC; 98% atom D. CAS No. 1219805-99-8. Molecular formula: C11H8D6N4O4. Mole weight: 272.29.
Doxofylline Impurity 1
Doxofylline Impurity 1 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 1-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide. Grade: > 95%. CAS No. 1429636-74-7. Molecular formula: C10H16N4O3. Mole weight: 240.26.
Doxofylline Impurity 10
Doxofylline Impurity 10 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: ethyl 7-theophyllineacetate; (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-acetic acid ethyl ester. CAS No. 7029-96-1. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Doxofylline Impurity 11
Doxofylline Impurity 11 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. CAS No. 109403-76-1. Molecular formula: C15H16N8O4. Mole weight: 372.34.
Doxofylline Impurity 12
Doxofylline Impurity 12 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: Doxofylline Impurity B. CAS No. 254760-82-2. Molecular formula: C11H16N4O4. Mole weight: 268.27.
Doxofylline Impurity 14
Doxofylline Impurity 14 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Molecular formula: C12H18N4O5. Mole weight: 298.29.
Doxofylline Impurity 19
Doxofylline Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1021-65-4. Molecular formula: C11H16N4O2. Mole weight: 236.28. Catalog: APB1021654.
Doxofylline Impurity 2
Doxofylline Impurity 2 (Theophylline Impurity 2) is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: Theophylline Impurity 1; 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-acetaldehyde; 7-(Formylmethyl)theophylline; 7-Theophyllineacetaldehyde. Grade: > 95%. CAS No. 5614-53-9. Molecular formula: C9H10N4O3. Mole weight: 222.20.
Doxofylline Impurity 4
Doxofylline Impurity 4 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 1-((1,3-Dioxolan-2-yl)methyl)-4-(1,3-dimethylureido)-1H-imidazole-5-carboxylic Acid; 2095554-12-2; F95323. Grade: >98%. CAS No. 2095554-12-2. Molecular formula: C11H16N4O5. Mole weight: 284.27.
Doxofylline Impurity 5
Doxofylline Impurity 5 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 2,4(1H,3H)-Dione, 1,3-dimethyl-6,7,9,10-tetrahydro-7,10-epoxy[1,4]oxazepino[5,4-f]purine-. Grade: >98%. Molecular formula: C11H12N4O4. Mole weight: 264.24.
Doxofylline Impurity 6
Doxofylline Impurity 6 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Grade: >98%. CAS No. 1429636-72-5. Molecular formula: C11H16N4O4. Mole weight: 268.27.
Doxofylline Impurity 7
Doxofylline Impurity 7 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Grade: >98%. Molecular formula: C10H14N4O5. Mole weight: 270.24.
Doxofylline Impurity 8
Doxofylline Impurity 8 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Molecular formula: C9H13N3O4. Mole weight: 227.22.
Doxofylline Impurity 9
Doxofylline Impurity 9 is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 7-(2',2'-Diethoxyethyl)theophylline1111. CAS No. 43135-57-5. Molecular formula: C13H20N4O4. Mole weight: 296.32.
Doxofylline Related Compound D
Doxofylline Related Compound D is a Doxofylline impurity. Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Grade: >98%. Molecular formula: C9H14N4O5. Mole weight: 258.23.
Doxorubicin
Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: Daunorubicin Impurity D; Daunorubicin EP Impurity D; (8S,10S)-10-[(3-Aamino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Adriamycin; Doxil; Adriablastin; Doxorubicine; Adriblastina; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Caelyx; Hydroxydaunorubicin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-; NSC 123127; (1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Epirubicin EP Impurity C. Grade: >98%. CAS No. 23214-92-8. Molecular formula: C27H29NO11. Mole weight: 543.52.
Doxorubicin (Adriamycin, 14-Hydroxydaunomycin)
Doxorubicin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an antitumor agent for the treatment of a wide range of cancers. Doxorubicin has also been reported to exhibit anti-HIV and antibacterial activity. The mode of action of doxorubicin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 23214-92-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Doxorubicin Dimer Impurity 1
Doxorubicin Dimer Impurity 1 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(((2S,3S,4S,6R)-3-hydroxy-2-methyl-6-(((1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)tetrahydro-2H-pyran-4-yl)glycyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. Grade: ≥95%. Molecular formula: C54H56N2O21. Mole weight: 1069.05.
Doxorubicin Dimer Impurity 2
Doxorubicin Dimer Impurity 2 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Molecular formula: C44H46N2O16. Mole weight: 858.86.
Doxorubicin Dimer Impurity 3
Doxorubicin Dimer Impurity 3 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,8'S,10S,10'S)-8,8'-(4-Hydroxy-2-(hydroxymethyl)-1,3-dioxolane-2,4-diyl)bis(10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione); (R,S,S,S,8S,8'S,10S,10'S)-8,8'-(4-hydroxy-2-(hydroxymethyl)-1,3-dioxolane-2,4-diyl)bis(10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione). Molecular formula: C54H58N2O22. Mole weight: 1087.05.
Doxorubicin EP Impurity B
Doxorubicin EP Impurity B is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity B; Doxorubicin Ketal Impurity; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 14-bromine-13-dimethyl-actone-4'-daunorubicin; Doxorubicin EP Impurity B; (1S,3S)-3-(2-Bromo-1,1-dimethoxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 14-Bromo Ketal Daunorubicin; Daunorubicin bromoketal. Grade: 85%. CAS No. 106401-68-7. Molecular formula: C29H34BrNO11. Mole weight: 652.48.
Doxorubicin EP Impurity B
Doxorubicin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 106401-68-7. Molecular formula: C29H34BrNO11. Mole weight: 651.13. Catalog: APB106401687.
Doxorubicin EP Impurity C hydrobromide dihydrate
Doxorubicin EP Impurity C hydrobromide dihydrate is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(bromoacetyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione dihydrate hydrobromide; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromoacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione dihydrate Hydrobromide; 14-Bromodaunomycin dihydrate Hydrobromide Salt; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(bromoacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrate, Hydrobromide (1:2:1); 14-Bromodaunorubicin dihydrate Hydrobromide. Molecular formula: C27H28BrNO10.2H2O.HBr. Mole weight: 723.36.
Doxorubicin HCl. Group: Biochemicals. Alternative Names: Adriamycin; (8S-cis)10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11- trihydroxy-8-(hydroacetyl)-1-methoxy-5,12- naphthacenedione. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C27H29NO11·HCl. US Biological Life Sciences.
Worldwide
Doxorubicin hydrochloride
Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Purity: 0.9958. Product ID: ACM25316409-1. Alfa Chemistry ISO 9001:2015 Certified.
Doxorubicin hydrochloride
100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-100mg. Molecular Weight 579.98. See USA prepack pricing.
Doxorubicin hydrochloride
25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-25mg. Molecular Weight 579.98. See USA prepack pricing.
Doxorubicin hydrochloride
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC 50 s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxydaunorubicin hydrochloride; ADR. CAS No. 25316-40-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15142.
Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: Daunorubicin EP Impurity D hydrochloride; (8S,10S)-10-[(3-Aamino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Doxorubicine hydrochloride; Adriblastina hydrochloride; 14-Hydroxydaunomycin hydrochloride; 14-Hydroxydaunorubicine hydrochloride; Hydroxydaunorubicin hydrochloride; (1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride; Epirubicin EP Impurity C hydrochloride. Grade: >98%. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Mole weight: 579.98.
Doxorubicin Hydrochloride
Used as an antineoplastic. Group: Biochemicals. Alternative Names: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriacin; Adriblastina; Adriamycin; Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg. US Biological Life Sciences.
The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Doxorubicin, Hydrochloride - CAS 25316-40-9
Doxorubicin HCl, CAS 25316-40-9, is an antitumor antibiotic that inhibits topoisomerase II (IC?? = 100 nM). Group: Fluorescence/luminescence spectroscopy.