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| Product | Description | |
|---|---|---|
| Erlotinib Carboxylic Acid | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grade: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. |  |
| Erlotinib-d6 | Erlotinib-d 6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: CP-358774-d6; NSC 718781-d6; OSI-774-d6. CAS No. 1034651-23-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-50896S. |  |
| Erlotinib-[d6] | Erlotinib-[d6] is the labelled analogue of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: Erlotinib D6. Grade: 95% by HPLC; 98% atom D. CAS No. 1034651-23-4. Molecular formula: C22H17D6N3O4. Mole weight: 399.48. | |
| Erlotinib-d6 hydrochloride | Erlotinib-d 6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: CP-358774-d6 hydrochloride; NSC 718781-d6 hydrochloride; OSI-774-d6 hydrochloride. CAS No. 1189953-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12008S. | |
| Erlotinib-[d6] Hydrochloride | Erlotinib-[d6] Hydrochloride is the labelled analogue of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy-d3)-4-quinazolinamine Hydrochloride; 6,7-Bis(2-methoxyethoxy-d3)-4-(3-ethynylanilino)quinazoline Hydrochloride; [6,7-Bis(2-methoxyethoxy-d3)quinazolin-4-yl]-(3-ethynylphenyl)amine Hydrochloride; Erlotinib D6 Hydrochloride. Grade: 98% by CP; 98% atom D. CAS No. 1189953-78-3. Molecular formula: C22H18D6ClN3O4. Mole weight: 435.93. | |
| Erlotinib-d6, Hydrochloride Salt (N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt) | Source: Synthetic. Group: Biochemicals. Alternative Names: N- (3-Ethynylphenyl) -6, 7-bis (2-tride uteromethoxyethoxy) -4-quinazolinamine, Hydrochloride Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Erlotinib hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H24ClN3O4. CAS No. 183319-69-9. Prepack ID 82977875-1g. Molecular Weight 429.9. See USA prepack pricing. |  |
| Erlotinib hydrochloride | Erlotinib HCl potently inhibits EGFR activation in intact cells including HNS human head and neck tumor cells (IC50 = 20 nM), DiFi humancolon cancer cells and MDA MB-468 human breast cancer cells. Uses: Antineoplastic agents. Synonyms: OSI-744; OSI744; OSI 744; Tarceva; 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride; 6,7-bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride. Grade: >98%. CAS No. 183319-69-9. Molecular formula: C22H23N3O4.HCl. Mole weight: 429.90. | |
| Erlotinib Hydrochloride | Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC 50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride. CAS No. 183319-69-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-12008. | |
| Erlotinib Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: [6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, OSI 774, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride, Erlotinib hydrochloride, Tarceva, CP 358774. |  |
| Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231) | A free base form of the EGFR inhibitor Erlotinib Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
| Erlotinib (Hydrochloride) (Standard) | Erlotinib (Hydrochloride) (Standard) is the analytical standard of Erlotinib (Hydrochloride). This product is intended for research and analytical applications. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC 50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 183319-69-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12008R. | |
| Erlotinib Hydroxy Metabolite | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grade: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
| Erlotinib impurity 1 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grade: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
| Erlotinib Impurity 11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grade: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Erlotinib Impurity 12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grade: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
| Erlotinib Impurity 13 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile. Grade: > 95%. CAS No. 236750-65-5. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Erlotinib Impurity 14 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-Amino-4,5-bis(2-methoxyethoxy)benzamide. Grade: > 95%. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.31. | |
| Erlotinib Impurity 15 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: ethyl 2-amino-3,4-bis(2-methoxyethoxy)benzoate. Grade: > 95%. Molecular formula: C15H23NO6. Mole weight: 313.35. | |
| Erlotinib Impurity 16 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((7,8-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzonitrile. Grade: > 95%. Molecular formula: C22H23N3O6. Mole weight: 393.45. | |
| Erlotinib impurity 2 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-Chloro-6-(2-Chloroethoxy)-7-(2-Methoxyethoxy)-Quinazoline. Grade: > 95%. CAS No. 183322-19-2. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib Impurity 2 (4-Chloro-7-(2-Chloroethoxy)-6-(2-Methoxyethoxy)-Quinazoline) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-chloro-7-(2-chloroethoxy)-6-(2-methoxyethoxy)quinazoline. Grade: > 95%. CAS No. 183322-20-5. Molecular formula: C13H14Cl2N2O3. Mole weight: 317.17. | |
| Erlotinib impurity 3 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2,4-dichloro-6,7-bis(2-methoxyethoxy)quinazoline. Grade: > 95%. Molecular formula: C14H16Cl2N2O4. Mole weight: 347.20. | |
| Erlotinib Impurity 34 | Erlotinib Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-vinylaniline. CAS No. 15411-43-5. Molecular formula: C8H9N. Mole weight: 119.16. Catalog: APB15411435. | |
| Erlotinib impurity 4 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)benzoic acid. Grade: > 95%. Molecular formula: C21H23N3O6. Mole weight: 413.43. | |
| Erlotinib Impurity 5 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-methoxyethoxy)-N-phenylquinazolin-4-amine. Grade: > 95%. Molecular formula: C20H25N3O4. Mole weight: 369.42. | |
| Erlotinib impurity, 6-(2-chloroethoxy)-7-(2-methoxyethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 7-(2-chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-Quinazolinamine. Grade: > 95%. CAS No. 183321-85-9. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6-(2-methoxyethoxy)-7-(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)quinazolin-4-amine. Grade: > 95%. CAS No. 183321-83-7. Molecular formula: C21H20ClN3O3. Mole weight: 397.86. | |
| Erlotinib impurity, 6,7-bis(2-chloroethoxy) | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-bis(2-chloroethoxy)-N-(3-ethynylphenyl)quinazolin-4-amine. Grade: > 95%. CAS No. 183321-82-6. Molecular formula: C20H17Cl2N3O2. Mole weight: 402.28. | |
| Erlotinib Impurity 7 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride. Grade: > 95%. CAS No. 183322-17-0. Molecular formula: C15H23NO6 HCl. Mole weight: 349.81. | |
| Erlotinib Impurity 74 | Erlotinib Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,5-bis(2-methoxyethoxy)-2-nitrobenzoic acid. CAS No. 1001416-73-4. Molecular formula: C13H17NO8. Mole weight: 315.28. Catalog: APB1001416734. | |
| Erlotinib Impurity 76 | Erlotinib Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. CAS No. 1241475-15-9. Molecular formula: C16H25N3O5. Mole weight: 339.39. Catalog: APB1241475159. | |
| Erlotinib Impurity 8 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib; N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine. Grade: > 95%. CAS No. 328528-74-1. Molecular formula: C20H22BrN3O4. Mole weight: 448.32. | |
| Erlotinib Impurity 9 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N-(3-cyanophenyl)acetamide. Grade: > 95%. Molecular formula: C24H25N3O5. Mole weight: 435.48. | |
| Erlotinib mesylate | Erlotinib is an EGFR inhibitor. The drug follows Iressa (gefitinib), which was the first drug of this type. Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. By inhibiting the ATP, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. Synonyms: Tarceva; CP-358774; CP 358774; CP358774; OSI-774; OSI 774; OSI774; NSC 718781; NSC718781; NSC-718781; R 1415; R1415; R-1415. Grade: >98%. CAS No. 248594-19-6. Molecular formula: C23H27N3O7S. Mole weight: 489.54. | |
| Erlotinib metabolite M11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]acetic Acid. Grade: > 95%. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.40. | |
| Erlotinib metabolite M12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline; 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol; 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. CAS No. 183321-84-8. Molecular formula: C20H19N3O4. Mole weight: 365.389. | |
| Erlotinib O-Desmethyl Metabolite Isomer | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grade: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42. | |
| Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl | OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grade: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874. | |
| Erlotinib (Standard) | Erlotinib (Standard) is the analytical standard of Erlotinib. This product is intended for research and analytical applications. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC 50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC 50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer [1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 183321-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50896R. | |
| ER membrane protein complex subunit 1 isoform 3 precursor (640-648) | ER membrane protein complex subunit 1 isoform 3 precursor (640-648) is amino acids 640 to 648 fragment of ER membrane protein complex subunit 1 isoform 3 precursor. ER membrane protein complex subunit 1 is a part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. This peptide can be used in Ovarian carcinoma research. | |
| ERO1 Inhibitor I, Erodoxin (Endoplasmic Reticulum Oxidase 1 Inhibitor, 1-Bromo-5-methoxy-2,4-dinitrobenzene) | A cell-permeable dinitrobromobenzene compound that acts as a selective inhibitor of yeast Endoplasmic Reticulum Oxidase 1 (ERO1), but has somewhat weaker activity against mouse ERO1a (IC50=400uM). Predicted to form thiol adducts and inhibits ERO1-dependent oxidation of thioredoxin-1 (Trx1) activity in vitro. Shown to cluster with genes involved in protein folding, glycosylation and cell wall biosynthesis, and delay carboxypeptidase Y (CPY) processing to the vacuolar form in wt-yeast cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C?H?BrN?O?, Molecular Weight: 277. US Biological Life Sciences. | Worldwide |
| ERO1 Inhibitor II, EN460 | A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1alpha and inhibits its activity (IC50 = 1.9uM). Also prevents ERO1 re-oxidation both in vitro and in mouse embryonic fibroblasts. Activates the unfolded protein response and protects ER-stressed 293T cells. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. Can inhibit ERO1alpha even in the presence of an excess amount of competing thiols. EN460 binding to ERO1alpha is shown to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme. Its inhibitory action appears to be irreversible, however addition of FAD and tris (hydroxypropyl) phosphine can restore some enzyme activity. Group: Biochemicals. Alternative Names: (Z)-2-Chloro-5-(4,5-dihydro-5-oxo-4-((5-phenyl-2-furanyl)methylene)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzoic Acid, (Z)-2-Chloro-5-(5-oxo-4-((5-phenylfuran-2-yl)methylene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic Acid. Grades: Highly Purified. CAS No. 496807-64-8. Pack Sizes: 25mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 460.8. US Biological Life Sciences. | Worldwide |
| ERRα antagonist-1 | ERRα antagonist-1, a selective and high affinity antagonist of estrogen-related receptor α (ERRα), inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β with IC50s of 170 and 180 nM, respectively. It does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1. Synonyms: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine; ERRa antagonist-1; 5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-. Grade: ≥95%. CAS No. 1072145-33-5. Molecular formula: C21H19N3S2. Mole weight: 377.53. | |
| ERRγ Inverse Agonist 1 | ERRγ Inverse Agonist 1 is a potent, selective and orally bioavailable inverse agonist of Estrogen-related Receptor grammar (ERRγ), with an IC50 of 40 nM. Synonyms: Benzenebutanol, δ-[(3-hydroxyphenyl)[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]methylene]-, hydrochloride (1:2), (δE)-; 3-{(1E)-5-Hydroxy-1-[4-(4-isopropyl-1-piperazinyl)phenyl]-2-phenyl-1-penten-1-yl}phenol dihydrochloride. CAS No. 2316832-86-5. Molecular formula: C30H38Cl2N2O2. Mole weight: 529.54. | |
| ErSO | ErSO is a selective anticipatory unfolded protein response ( a-UPR ) activator. ErSO acts through ERα to elicit strong and sustained cytotoxic activation of the a-UPR. ErSO can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407860-35-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132247. | |
| Ersodetug | Ersodetug is an anti- INSR (insulin receptor) human IgG2 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2410976-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990712. | |
| ErSO-DFP | ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ER?+) cancer cells with a wider selectivity window than ErSO (HY-132247). ErSO-DFP displays antitumor activity against MCF-7 in mice. ErSO-DFP can cross the blood brain barrier[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768139-76-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144070. | |
| Ertapenem | Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections. Synonyms: (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl-4-methyl-7-oxo-, (4R,5S,6S)-; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, (4R-(3(3S*,5S*),4α,5β,6β(R*)))-. Grade: 95%. CAS No. 153832-46-3. Molecular formula: C22H25N3O7S. Mole weight: 475.52. | |
| Ertapenem | Ertapenem. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,5S,6S)-3-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid. CAS No. 153832-46-3. Molecular formula: C22H25N3O7S. Mole weight: 475.14. Catalog: APB153832463. | |
| Ertapenem Acetic Acid Adduct Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S)-1-acetyl-5-((1S,2R)-1-carboxy-2-hydroxypropyl)-3-(((3R,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid. Grade: > 95%. Molecular formula: C24H27N3O9S. Mole weight: 533.56. | |
| Ertapenem-[d4] Disodium | Ertapenem-[d4] Disodium is the labelled analogue of Ertapenem, which is a carbapenem antibiotic medication. Synonyms: Ertapenem-d4 Disodium. CAS No. 1356934-56-9. Molecular formula: C22H19D4N3Na2O7S. Mole weight: 523.50. | |
| Ertapenem Dimer Amide Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: Ertapenem Dimer III; (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(2S,3R)-5-Carboxy-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-2,3-dihydro-3-methyl-1H-pyrrol-1-yl]carbonyl]phenyl]amino]carbonyl]-3-pyrr. Grade: > 95%. CAS No. 1199797-42-6. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Dimer H2Oa | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(1R,2S)-2-Carboxy-2-[(2S,3R)-5-carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-1-methylethoxy]carbonyl]phenyl]amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1. Grade: > 95%. Molecular formula: C44H48N6O14S2. Mole weight: 933.03. | |
| Ertapenem Dimer I | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-1-[(2S,3R)-2-[(2S,3R)-5-Carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-3-hydroxy-1-oxobutyl]-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hyd. Grade: > 95%. CAS No. 1199797-41-5. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Dimer II | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: Ertapenem Dimer Ester Impurity; (4R,5S,6S)-3-[[(3S,5S)-5-[[[3-[[(1R,2S)-2-Carboxy-2-[(2S,3R)-5-carboxy-4-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-3-methyl-2H-pyrrol-2-yl]-1-methylethoxy]carbonyl]phenyl]amino]carbonyl. Grade: > 95%. CAS No. 402955-38-8. Molecular formula: C44H50N6O14S2. Mole weight: 951.05. | |
| Ertapenem Disodium | Group 1 carbapenem antibiotic. An antibacterial. Group: Biochemicals. Alternative Names: (4R, 5S, 6S) -3-[[ (3S, 5S) -5-[[ (3-Carboxyphenyl) amino]carbonyl]-3-pyrrolidinyl]thio]-6-[ (1R) -1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3. 2. 0]hept-2-ene-2-carboxylic Acid Sodium Salt; L 749. Grades: Highly Purified. CAS No. 153832-38-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ertapenem Disodium | It is a long-acting, broad-spectrum antibiotic that is in the β-lactam subclass known as carbapenems. It inhibits the synthesis of bacterial cell walls by attaching to penicillin-binding proteins. It has activity against Gram-positive and Gram-negative bacteria. Synonyms: Ertapenem sodium; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, disodium salt, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-; L 749. Grade: ≥97%. CAS No. 153832-38-3. Molecular formula: C22H23N3Na2O7S. Mole weight: 519.48. | |
| Ertapenem Impurity 22 | Ertapenem Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153773-82-1. Molecular formula: C22H24N3NaO7S. Mole weight: 497.5. Catalog: APB153773821. | |
| Ertapenem Impurity 36 | Ertapenem Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,3'-(((2S,2'S,4S,4'S)-4,4'-disulfanediylbis(1-(((4-nitrobenzyl)oxy)carbonyl)pyrrolidine-2,2'-carbonyl))bis(azanediyl))dibenzoic acid. CAS No. 1401451-19-1. Molecular formula: C40H36N6O14S2. Mole weight: 888.88. Catalog: APB1401451191. | |
| Ertapenem Impurity DIPP | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-((2S,4S)-1-(diisopropoxyphosphoryl)-4-mercaptopyrrolidine-2-carboxamido)benzoic acid. Grade: > 95%. CAS No. 220031-86-7. Molecular formula: C18H27N2O6PS. Mole weight: 430.46. | |
| Ertapenem Impurity Pro-maba | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (S)-3-(pyrrolidine-2-carboxamido)benzoic acid. Grade: > 95%. CAS No. 724700-26-9. Molecular formula: C12H14N2O3. Mole weight: 234.26. | |
| Ertapenem Methanolysis Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (2S,3R)-4-(((3R,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-2-((2R,3S)-2-hydroxy-4-oxopentan-3-yl)-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid. Grade: > 95%. Molecular formula: C23H27N3O7S. Mole weight: 489.55. | |
| Ertapenem N-Carbonyl Dimer Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-[[(3S,5S)-1-[3-[[[(2S,4S)-4-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-2-pyrrolidinyl]carbonyl]amino]benzoyl]-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydro. Grade: > 95%. CAS No. 1199797-43-7. Molecular formula: C44H48N6O13S2. Mole weight: 933.03. | |
| Ertapenem Oxazinone Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (3S,4S,4aS,5R)-4-acetyl-6-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-3,5-dimethyl-1-oxo-3,4,4a,5-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazine-7-carboxylic acid. Grade: > 95%. Molecular formula: C23H25N3O9S. Mole weight: 519.53. | |
| Ertapenem Ring Open Impurity | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 1H-Pyrrole-2-acetic acid, 5-carboxy-4-[[(3S,?5S)?-5-[[(3-carboxyphenyl)?amino]?carbonyl]?-3-pyrrolidinyl]?thio]?-2,?3-dihydro-α-[(1R)?-1-hydroxyethyl]?-3-methyl-, (αS,?2S,?3R)?-. Grade: > 95%. CAS No. 357154-27-9. Molecular formula: C22H27N3O8S. Mole weight: 493.54. | |
| Ertapenem Side Chain Enantiomer 1 | An intermediate of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-[[[(2S,4S)-1-(4-Nitrobenzyloxycarbonyl)-4-mercaptopyrrolidin-2-yl]carbonyl]amino]benzoic Acid; (2S-cis)-2-[[(3-Carboxyphenyl)amino]carbonyl]-4-mercapto-1-pyrrolidinecarboxylic Acid 1-[(4-Nitrophenyl)methyl] Ester. Grade: > 95%. CAS No. 202467-69-4. Molecular formula: C20H19N3O7S. Mole weight: 445.45. | |
| Ertapenem Side Chain Enantiomer 2 HCl | An intermediate of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 3-((2S,4S)-4-mercaptopyrrolidine-2-carboxamido)benzoic acid HCl. Grade: > 95%. CAS No. 503607-49-6. Molecular formula: C12H14N2O3S. HCl. Mole weight: 266.32 36.46. | |
| Ertapenem side chain impurity (propyl ester) | An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: propyl 3-((2S,4S)-4-mercaptopyrrolidine-2-carboxamido)benzoate. Grade: > 95%. Molecular formula: C15H20N2O3S. Mole weight: 308.40. | |
| Ertapenem sodium | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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