A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| EPZ004777 | EPZ004777 is a potent, selective inhibitor of DOT1L. Treatment of mixed lineage leukemia (MLL) cells with EPZ004777 selectively inhibits H3K79 methylation and blocks expression of leukemogenic genes. Exposure of leukemic cells to EPZ004777 results in selective killing of those cells bearing the MLL gene translocation, with little effect on non-MLL-translocated cells. Finally, in vivo administration of EPZ004777 leads to extension of survival in a mouse MLL xenograft model. These results provide compelling support for DOT1L inhibition as a basis for targeted therapeutics against MLL. Uses: Reprogramming. Synonyms: EPZ004777; EPZ 004777; EPZ-004777. Grades: 0.98. CAS No. 1338466-77-5. Molecular formula: C28H41N7O4. Mole weight: 539.681. |  |
| EPZ004777 hydrochloride | EPZ004777 selectively inhibits cellular H3K79 methylation and inhibits expression of key MLL fusion target genes. Following DOT1L inhibition, EPZ004777 selectively inhibits proliferation of MLL-Rearranged cell lines and MLL-AF9-transformed murine hematopoietic cells. In addition, EPZ004777 also induces differentiation and apoptosis in MLL-rearranged cells. EPZ004777 selectively inhibits proliferation of MLL-AF10 and CALM-AF10-transformed murine bone marrow cells. DOT1L inhibition by EPZ004777 results in significantly decreased proliferation, decreased expression of MLL-AF6 target genes, and cell cycle arrest of MLL-AF6-transformed cells. Synonyms: EPZ 004777 hydrochloride; EPZ-004777 hydrochloride; EPZ004777 hydrochloride. Grades: >98%. CAS No. 1380316-03-9. Molecular formula: C28H42ClN7O4. Mole weight: 576.13. | |
| EPZ005687 | EPZ005687 is a selective EZH2 enzyme inhibitor with Ki of 24 nM. It is 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases. EPZ005687 can block trimethylation of the PRC2 target histone 3 lysine 27 with IC50 value of 80 nM, decreasing the proliferation of lymphoma cells carrying mutant, but not wild-type, EZH2. No development of preclinical research for the treatment of Cancer, Lymphoma and Solid tumours was reported. Uses: Cancer; lymphoma; solid tumours. Synonyms: EPZ005687; EPZ 005687; EPZ-005687; 1-Cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carboxamide; 1-Cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(4-(morpholinomethyl)phenyl)-1H-indazole-4-carboxamide. Grades: 98%. CAS No. 1396772-26-1. Molecular formula: C32H37N5O3. Mole weight: 539.67. | |
| EPZ011989 | EPZ011989 is a potent, orally-available EZH2 inhibitor with robust in vivo activity. EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma. Synonyms: EPZ011989; EPZ-011989; EPZ 011989. Grades: 98%. CAS No. 1598383-40-4. Molecular formula: C35H51N5O4. Mole weight: 605.82. | |
| EPZ011989 | EPZ011989 is a potent, orally-available EZH2 inhibitor with robust in vivo activity. EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma. EPZ011989 represents a powerful tool for the expanded exploration of EZH2 activity in biology. Inhibitors of the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2) may have significant therapeutic potential for the treatment of B cell lymphomas and other cancer indications. The ability of the scientific community to explore fully the spectrum of EZH2-associated pathobiology has been hampered by the lack of in vivo-active tool compounds for this enzyme. Group: Inhibitors. Alternative Names: EPZ011989; EPZ-011989; EPZ 011989. CAS No. 1598383-40-4. Molecular formula: C35H51N5O4. Mole weight: 605.82. Appearance: Solid powder. Purity: >98%. IUPACName: N- ( (4, 6-dimethyl-2-oxo-1, 2-dihydropyridin-3-yl)methyl)-3- (ethyl ( (1r, 4r)-4- ( (2-methoxyethyl) (methyl)amino)cyclohexyl)amino)-2-methyl-5- (3-morpholinoprop-1-yn-1-yl)benzamide. Canonical SMILES: O=C (NCC1=C (C)C=C (C)NC1=O)C2=CC (C#CCN3CCOCC3)=CC (N (CC)[C@H]4CC[C@H] (N (CCOC)C)CC4)=C2C. Catalog: ACM1598383404. |  |
| EPZ011989 trifluoroacetate | EPZ011989 trifluoroacetate is the trifluoroacetate salt form of EPZ011989. EPZ011989 is a potent and orally bioavailable inhibitor that specifically targets the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2), with significant tumor growth in. Synonyms: EPZ011989 TFA salt; EPZ011989 TFA; EPZ 011989 TFA; EPZ-011989 TFA; N-[ (4, 6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl (methyl)amino]cyclohexyl]amino]-2-methyl-5- (3-morpholin-4-ylprop-1-ynyl)benzamide; 2, 2, 2-trifluoroacetic acidEPZ011989 (trifluoroacetate). CAS No. 1598383-41-5. Molecular formula: C37H52F3N5O6. Mole weight: 719.83. | |
| EPZ015666 | EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of 96-904 nM. Synonyms: EPZ015666; EPZ-015666; EPZ 015666; GSK3235025; GSK-3235025; GSK 3235025. Grades: >98%. CAS No. 1616391-65-1. Molecular formula: C20H25N5O3. Mole weight: 383.44. | |
| EPZ015666 (PRMT5, HRMT1L5, IBP72, JBP1, SKB1, PRMT Protein) | EPZ015666 is a potent, selective, competitive PRMT5 inhibitor (IC50 = 22nM). EPZ015666 exhibits >10,000-fold specificity for PRMT5 vs. other methyltransferases. EPZ015666 blocks the association of PRMT5 with methylosome protein 50 (WDR77), which is necessary to form an active methyltransferase complex. Treatment of MCL cell lines with nM concentrations of EPZ015666 leads to inhibition of SmD3 methylation and cell death. Group: Biochemicals. Grades: Highly Purified. CAS No. 1616391-65-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| EPZ015866 | EPZ015866,also called as GSK591, is a chemical probe for PRMT5 which has a role in diverse cellular processes including tumorigenesis. It exhibits excellent selectivity against a panel of methyltransferases. Inhibits the PRMT5/MEP50 complex from methylati. Synonyms: GSK591; GSK-591; GSK 591; EPZ015866; EPZ-015866; EPZ 015866; GSK 3203591; GSK-3203591; GSK3203591; 2- (cyclobutyl amino) -N- [ (2S) -3- (3, 4-di hydro-1H-isoquinolin-2-yl ) -2- hydroxypropyl ] pyridine-4-carboxamide EPZ015866GSK591GTPL8954S CHEMBL16220740GSK32035912- (cyclobutyl amino) -N- [ (2S) -2- hydroxy-3- (1, 2, 3, 4-tetra hydroisoquinolin-2-yl ) propyl ] pyridine-4-carbo. CAS No. 1616391-87-7. Molecular formula: C22H28N4O2. Mole weight: 380.48. | |
| EPZ020411 | EPZ020411, with potent anticancer activity, is an orally bioactive, selective inhibitor of PRMT6/8/1 with over 100-fold selective for other histone methyltransferases including four arginine methyltransferases (PRMT3, PRMT4, PRMT5, and PRMT7). Synonyms: N,N'-dimethyl-N'-[[5-[4-[3-[2-(oxan-4-yl)ethoxy]cyclobutyl]oxyphenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineEPZ020411; EPZ 020411; EPZ-020411CHEMBL3589039GTPL9243SCHEMBL17 62195749LN, N'-Di methyl -N- ( {3- [4- ( {trans-3- [2- (Tetra hydro-2h-Pyran-4-yl ) ethoxy] cyclobutyl } oxy) pheny l. CAS No. 1700663-41-7. Molecular formula: C25H38N4O3. Mole weight: 442.59. | |
| EPZ020411 HCl | EPZ020411 hydrochloride is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM, and it displays >10-fold and 20-fold selectivity over PRMT1/8. Synonyms: EPZ-020411 hydrochloride. Grades: ≥97%. CAS No. 2070015-25-5. Molecular formula: C25H39ClN4O3. Mole weight: 479.06. | |
| EPZ-5676 | EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon intravenous administration, EPZ-5676 specifically blocks the activity of the histone lysine-methyltransferase DOT1L, thereby inhibiting the methylation of nucleosomal histone H3 on lysine 79 (H3K79) that is bound to the mixed lineage leukemia (MLL) fusion protein which targets genes and blocks the expression of leukemogenic genes. This eventually leads to an induction of apoptosis in the leukemic cells bearing the MLL gene translocations. DOT1L, a non-SET domain-containing histone methyltransferase, specifically methylates H3K79 and plays a key role in normal cell differentiation and in the development of leukemia with MLL gene rearrangement on chromosome 11 and promotes the expression of leukemia-causing genes. Synonyms: EPZ-5676; EPZ5676; EPZ 5676. CAS No. 1380288-87-8. Molecular formula: C30H42N8O3. Mole weight: 562.719. | |
| EPZ-6438 | EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. EPZ-6438 induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Treatment of xenograft-bearing mice with EPZ-6438 leads to dose-dependent regression of MRTs with correlative diminution of intratumoral trimethylation levels of lysine 27 on histone H3, and prevention of tumor regrowth after dosing cessation. These data demonstrate the dependency of SMARCB1 mutant MRTs on EZH2 enzymatic activity and portend the utility of EZH2-targeted drugs for the treatment of these genetically defined cancers. EPZ-6438 is currently in clinical trials. Synonyms: EPZ-6438; EPZ 6438; EPZ6438; E7438; E-7438; E 7438; Tazemetostat. Grades: 98%. CAS No. 1403254-99-8. Molecular formula: C34H44N4O4. Mole weight: 572.75. | |
| Equilenin | Equilenin is a B-ring unsaturated estrogen and one of the main ingredients in Premarin, a drug commonly used in estrogen replacement therapy. Equilenin can bind to estrogen receptors in the body and exert effects similar to endogenous estrogen. Equilenin can be used in estrogen replacement therapy and breast cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 517-09-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-116865. |  |
| Equilenin | Equilenin is an estrogenic steroid hormone obtained from the urine of pregnant mares. Synonyms: 3-Hydroxyestra-1,3,5,7,9-pentaen-17-one; (+)-Equilenin; 3-Hydroxyestra-1,3,5(10),6,8-pentaen-17-one. Grades: > 95%. CAS No. 517-09-9. Molecular formula: C18H18O2. Mole weight: 266.34. | |
| Equilenin | Equilenin. Group: Biochemicals. Alternative Names: 3-Hydroxyestra-1,3,5,7,9-pentaen-17-one; (+)-Equilenin; 3-Hydroxyestra-1,3,5(10),6,8-pentaen-17-one. Grades: Highly Purified. CAS No. 517-09-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C18H18O2. US Biological Life Sciences. | Worldwide |
| Equilenin Sulfate Sodium | A metabolite of Equilin. Equilenin is an estrogenic steroid hormone obtained from the urine of pregnant mares. Synonyms: 3-(Sulfooxy)-estra-1,3,5,7,9-pentaen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5,7,9-pentaen-17-one HydrogenSulfate Monosodium Salt. Grades: > 95%. CAS No. 16680-48-1. Molecular formula: C18H17FO5S Na. Mole weight: 345.40 22.99. | |
| Equilin | An estrogen found in Premarin, which is a mixture of conjugated estrogens widely used in hormone replacement therapy. Group: Biochemicals. Alternative Names: 1,3,5,7-Estratetraen-3-ol-17-one; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one; 7-Dehydroestrone; NSC 10971. Grades: Highly Purified. CAS No. 474-86-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Equilin | Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: An estrogen. Synonyms: 3-Hydroxy-13-methyl-9,11,12,14,15,16-hexahydro-6H-cylcopenta(a)phenanthren-17-one. Grades: > 95%. CAS No. 474-86-2. Molecular formula: C18H20O2. Mole weight: 268.36. | |
| Equilin | Equilin (7-Dehydroestrone) is an important member of the large group of oestrogenic substances and is chemically related to menformon (oestrone). Equilin increases the growth of cortical neurons via an NMDA receptor-dependent mechanism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Dehydroestrone. CAS No. 474-86-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1176. | |
| Equilin 3-Benzoate | Equilin 3-Benzoate is an intermediate of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Synonyms: 3-(Benzoyloxy)-estra-1,3,5(10),7-tetraen-17-one; 3-Hydroxy-estra-1,3,5(10),7-tetraen-17-one Benzoate; Equilin benzoate; 17-Oxoestra-1,3,5(10),7-tetraen-3-yl benzoate; Estra-1,3,5(10),7-tetraen-17-one, 3-(benzoyloxy)-; Equilin Impurity 10. Grades: ≥95%. CAS No. 6030-80-4. Molecular formula: C25H24O3. Mole weight: 372.46. | |
| Equilin 3-Benzoate | Estrogen derivative. Displays inhibiton activity towards pig liver steroid Δ4-5 β-reductase. Group: Biochemicals. Alternative Names: 3-(Benzoyloxy)-estra-1,3,5(10),7-tetraen-17-one; 3-Hydroxy-estra-1,3,5(10),7-tetraen-17-one Benzoate. Grades: Highly Purified. CAS No. 6030-80-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Equilin 3-O-beta-D-Glucuronide Sodium Salt | A derivative of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Synonyms: 17-Oxoestra-1,3,5(10),7-tetraen-3-yl β-D-Glucopyranosiduronic Acid Monosodium Salt. Grades: > 95%. CAS No. 27610-12-4. Molecular formula: C24H27O8 Na. Mole weight: 466.46. | |
| Equilin 3-Sulfate-d4 Sodium Salt (stabilized with Tris, 50% w/w) | A labeled metabolite of Equilin. Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one-d4 Sodium Salt; t; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one-d4 Hydrogen Sulfate Sodium Salt; Sodium Equilin-d4 3-Monosulfate; Sodium Equilin-d4 Sulfate. Grades: Highly Purified. CAS No. 285979-81-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Equilin 3-sulfate sodium salt | Equilin 3-sulfate sodium salt. Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one sodium salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one hydrogen sulfate sodium salt; Sodium equilin 3-monosulfate. Grades: Highly Purified. CAS No. 16680-47-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H19NaO5S. US Biological Life Sciences. | Worldwide |
| Equilin 3-Sulfate Sodium Salt | A derivative of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: Estrogens. Synonyms: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate Sodium Salt; Sodium Equilin 3-Monosulfate. Grades: > 95%. CAS No. 16680-47-0. Molecular formula: C18H19O5S. Na. Mole weight: 370.4. | |
| Equilin 3-Sulfate Sodium Salt (Stabilized with Tris, 50% w/w) | Metabolite of Equilin. Equilin 3-Sulfate Sodium Salt (Stabilized with TRIS, 50% w/w). Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate Sodium Salt; Sodium Equilin 3-Monosulfate; Sodium Equilin Sulfate. Grades: Highly Purified. CAS No. 16680-47-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Equilin-d4 | Labeled Equilin. An estrogen found in Premarin, which is a mixture of conjugated estrogens widely used in hormone replacement therapy. Group: Biochemicals. Alternative Names: 1,3,5,7-Estratetraen-3-ol-17-one-d4; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one-d4; 7-Dehydroestrone-d4; NSC 10971-d4. Grades: Highly Purified. CAS No. 285979-79-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| equine arterivirus serine peptidase | In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab polyproteins. This enzyme is the main viral proteinase and processes five cleavage sites in the ORF1a protein and three in the ORF1b-encoded part of the ORF1ab protein to yield nonstructural proteins (nsp5-nsp12). It combines the catalytic system of a chymotrypsin-like serine peptidase (His-Asp-Ser catalytic triad) with the substrate specificity of a 3C-like serine peptidase (Glu or Gln) at the P1 position and a small amino-acid residue (Gly, Ser or Ala) at the P1' position. Cleavage of ORF1ab by this enzyme is essential for viral replication. Belongs in peptidase family S32. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.114. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4109; equine arterivirus serine peptidase; EC 3.4.21.114. Cat No: EXWM-4109. |  |
| Equisetin | Equisetin is an antibiotic produced by Fusarium equiseti NRRL 5537. Activity against gram-positive bacteria. Synonyms: (-)-Equisetin. Grades: >98%. CAS No. 57749-43-6. Molecular formula: C22H31NO4. Mole weight: 373.48. | |
| Equisetin | The tetramic acid equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against human immunodeficiency virus type 1 (HIV-1) integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3' end-processing and strand transfer as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core. Group: Biochemicals. Grades: Highly Purified. CAS No. 57749-43-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Equol | Cas No. 531-95-3. | |
| ER-000444793 | ER-000444793, a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening, inhibits mPTP with an IC50 of 2.8?μM. R-000444793 neither affected cyclophilin D (CypD) enzymatic activity, nor displaced of CsA from CypD protein, suggesting a mechanism independent of CypD inhibition. Synonyms: N-(2-benzylphenyl)-2-oxo-1H-quinoline-4-carboxamide; ER-000444793; ER 000444793; ER000444793. CAS No. 792957-74-5. Molecular formula: C23H18N2O2. Mole weight: 354.4. | |
| ER-27319 | ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201010-95-9. Pack Sizes: 5 mg. Product ID: HY-138961. | |
| ER 27319 maleate | ER 27319 maleate. Group: Biochemicals. Grades: Purified. CAS No. 1204480-26-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ER 27319 maleate | ER 27319 maleate is a selective Syk kinase inhibitor. It suppresses tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat and human mast cells, causing the abrogation of degranulation, TNF-α production (IC50 = 10 μM) and other related signaling events. Synonyms: ER27319 maleate; ER-27319 maleate; 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate; 9(10H)-Acridinone, 10-(3-aminopropyl)-3,4-dimethyl-, (2Z)-2-butenedioate (1:1); 3,4-Dimethyl-10-(3-aminopropyl)-9-acridone maleate. Grades: ≥99% by HPLC. CAS No. 1204480-26-1. Molecular formula: C18H20N2O.C4H4O4. Mole weight: 396.17. | |
| ER-27319 maleate | ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204480-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108489. | |
| ER 50891 | ER 50891 is an RARα receptor antagonist (IC50 = 31.2 nM). Synonyms: ER 50891; ER50891; ER-50891; 4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid. Grades: ≥99% by HPLC. CAS No. 187400-85-7. Molecular formula: C29H24N2O2. Mole weight: 432.51. | |
| ER 50891 | ER 50891. Group: Biochemicals. Grades: Purified. CAS No. 187400-85-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ER-67880 | ER-67880 is a novel and potent microtubule inhibitor with potential anticancer activity. Synonyms: ER 67880; ER67880; N-(3-chloro-1H-indol-7-yl)-4-methoxy-benzenesulfonamide. Grades: 98%. CAS No. 247186-96-5. Molecular formula: C15H13ClN2O3S. Mole weight: 336.79. | |
| ER-805751 | ER-805751 is a potent proteasome inhibitor. Synonyms: ER-80575; ER805751; ER 805751. Grades: 98%. CAS No. 565454-88-8. Molecular formula: C25H30N2O6. Mole weight: 454.52. | |
| ER 819762 | ER 819762 is a potent and selective EP4 receptor antagonist (IC50 = 59 nM) that inhibits EP4-mediated Th1 differentiation, Th17 cell expansion, and IL-23 secretion by activated dendritic cells. It was shown to suppress Th1 and Th17 cytokine production, collagen- and GPI-induced arthritis in mice. It attenuates CFA-induced inflammatory pain in rats. Uses: Analgesic. Synonyms: ER819762; ER 819762; ER-819762. (10S)-1'-[(3,5-Dimethylphenyl)methyl]-2-ethyl-5,10-dihydro-7,9-dimethoxy-10-methylspiro[1H-imidazo[1,5-b][2]benzazepine-1,4'-piperidin]-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 1155773-15-1. Molecular formula: C30H39N3O3. Mole weight: 489.65. | |
| ERA63 | A selective agonist of estrogen receptor &alpha. Synonyms: ERA63; ERA 63; ERA-63; (7R,8R,9S,13S,14S,17R)-17-ethynyl-7,13-dimethyl-3-methylidene-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol. CAS No. 343248-86-2. Molecular formula: C22H30O. Mole weight: 310.47. | |
| Erabulenol A | Erabulenol A is a cholesteryl ester transfer protein (CETP) inhibitor produced by Penicillum sp. FO-5637. Synonyms: Deoxyherqueinone; Atrovenetin monomethyl ether. CAS No. 20887-73-4. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| Erabulenol B | Erabulenol B is a cholesteryl ester transfer protein (CETP) inhibitor produced by Penicillum sp. FO-5637. Molecular formula: C30H30O10. Mole weight: 550.55. | |
| Eragidomide | Eragidomide Inhibitor. Uses: Scientific use. Product Category: T10765. CAS No. 1860875-51-9. |  |
| Eragidomide | Eragidomide is a modulator of the E3 ligase cereblon and has antineoplastic activity. Synonyms: rac-2-(4-chlorophenyl)-N-({2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide; CC-90009; Cereblon modulator 1; NSC828250; CC 90009; CC90009; 4-chloro-N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-α,α-difluoro-benzeneacetamide. Grades: ≥98% by HPLC. CAS No. 1860875-51-9. Molecular formula: C22H18ClF2N3O4. Mole weight: 461.85. | |
| Erastin | Erastin Inhibitor. Uses: Scientific use. Product Category: T1765. CAS No. 571203-78-6. | |
| Erastin | Erastin is a selective antitumor agent that displays greater lethality in human tumor cells harboring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling. Group: Biochemicals. Alternative Names: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone. Grades: Highly Purified. CAS No. 571203-78-6. Pack Sizes: 1mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 547.04. US Biological Life Sciences. | Worldwide |
| Erastin | Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. Synonyms: Erastin. Grades: 0.98. CAS No. 571203-78-6. Molecular formula: C30H31ClN4O4. Mole weight: 547.04454. | |
| Erastin2 | Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter, which inhibits glutamate release in CCF-STTG1 cells with an IC50 of 0.0035 μM. Synonyms: 2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[4-(1-methylethoxy)[1,1'-biphenyl]-3-yl]-4(3H)-quinazolinone. Grades: ≥98%. CAS No. 1695533-44-8. Molecular formula: C36H35ClN4O4. Mole weight: 623.14. | |
| Erastin impurity 2 | Erastin impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H22N4O2. Mole Weight: 302.38. Catalog: APB11220. |  |
| Erastin impurity 4 | Erastin impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 361382-26-5. Molecular Formula: C16H23NO2. Mole Weight: 261.37. Catalog: APB361382265. | |
| Eravacycline | Eravacycline, also known as TP-434, a novel antibiotic. Eravacycline showed potent broad-spectrum activity against 90% of the isolates (MIC90) in each panel at concentrations ranging from 0.008 to 2 μg/ml for all species panels except those of Pseudomonas aeruginosa and Burkholderia cenocepacia (MIC90 values of 32 μg/ml for both organisms). Synonyms: TP-434; TP 434; TP434. Grades: 98%. CAS No. 1207283-85-9. Molecular formula: C27H31FN4O8. Mole weight: 558.56. | |
| Eravacycline dihydrochloride | Eravacycline, a novel fluorocycline previously known as TP-434, in virto has broad-spectrum activity against both Gram-positive and Gram-negative aerobic and anaerobic pathogens including important antimicrobial resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and extended-spectrum ?-lactamase (ESBL)-producing and carbapenemaseproducing Enterobacteriaceae and multidrug-resistant Acinetobacter baumannii. Synonyms: (4S,4aS,5aR,12aR)-4-(dimethylamino)-7-fluoro-1,10,11,12a-tetrahydroxy-3,12-dioxo-9-[(2-pyrrolidin-1-ylacetyl)amino]-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;dihydrochloride; Eravacycline (dihydrochloride). CAS No. 1334714-66-7. Molecular formula: C27H33Cl2FN4O8. Mole weight: 631.48. | |
| Eravacycline dihydrochloride | Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TP-434 dihydrochloride; TP-434-046. CAS No. 1334714-66-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16980A. | |
| Eravacycline Impurity 2 | Eravacycline Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204281-07-0. Molecular Formula: C28H33FN4O8. Mole Weight: 572.59. Catalog: APB2204281070. | |
| Eravacycline Impurity 3 | Eravacycline Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204281-08-1. Molecular Formula: C28H33FN4O8. Mole Weight: 572.59. Catalog: APB2204281081. | |
| ERB 041 | ERB 041 is a potent ER β agonist; displays >200-fold selectivity for ER β over ERα (IC50 values are 5 and 1216 nM for human ER β and ERα; 3.1 and 620 nM for rat ER β and ERα; and 3.7 and 750 nM for mouse ER β and ERα respectively). Group: Biochemicals. Alternative Names: 7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinylbenzoxazol-5-ol; Prinaberel. Grades: Highly Purified. CAS No. 524684-52-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ERB-041 | ERB 041 is a highly selective agonist of the ERβ subtype of the estrogen receptor, displays >200-fold selectivity for ERβ over Er&alpha. Uses: Potent erβ agonist. Synonyms: Prinaberel;2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol; ERB041; ERB 041; ERB041; Prinaberel; WAY-202041; WAY202041; WAY 202041 (4Z)-4-(7-ethenyl-5-hydroxy-3H-1,3-benzoxazol-2-ylidene)-2-fluorocyclohexa-2,5-dien-1-one. Grades: ≥98%. CAS No. 524684-52-4. Molecular formula: C15H10FNO3. Mole weight: 271.24. | |
| Erbium | Erbium. Group: Glass additives. Product ID: erbium. Molecular formula: 167.26g/mol. Mole weight: Er. [Er]. InChI=1S/Er. UYAHIZSMUZPPFV-UHFFFAOYSA-N. |  |
| Erbium | Erbium. Uses: Erbium has limited commercial use, but it is used as an alloy metal for vanadium to makeit easier to work and to form spring steel. the oxide of erbium is pink, which is used to colorglass and to make lasers that will operate at normal room temperatures. it has limited use ascontrol rods in nuclear fission reactors. Group: 3d printing materials. Alternative Names: Erbium Nanoparticle Dispersion; CTK0H6979; Erbium, foil, 50x50mm, thickness 1.0mm, as rolled, 99%; Erbium, wire reel, 50mm, diameter 1.0mm, hard, 99.9%; Erbium, lump, 25 mm max. lump size, weight 300 g, purity 99%; Erbium powder; Erbium ingot; 68Er; AC1L2N4K; Erbium, rod, 50mm, diameter 10.0mm, cast, 99%. CAS No. 7440-52-0. Product ID: erbium. Molecular formula: 167.259g/mol. Mole weight: Er. [Er]. InChI=1S/Er. UYAHIZSMUZPPFV-UHFFFAOYSA-N. | |
| Erbium | Erbium has limited commercial use, but it is used as an alloy metal for vanadium to makeit easier to work and to form spring steel. The oxide of erbium is pink, which is used to colorglass and to make lasers that will operate at normal room temperatures. It has limited use ascontrol rods in nuclear fission reactors. Group: Nanoparticles & nanopowders. Alternative Names: Erbium Nanoparticle Dispersion; CTK0H6979; Erbium, foil, 50x50mm, thickness 1.0mm, as rolled, 99%; Erbium, wire reel, 50mm, diameter 1.0mm, hard, 99.9%; Erbium, lump, 25 mm max. lump size, weight 300 g, purity 99%; Erbium powder; Erbium ingot; 68Er; AC1L2N4K; Erbium, rod, 50mm, diameter 10.0mm, cast, 99%. CAS No. 7440-52-0. Molecular formula: Er. Mole weight: 167.259g/mol. IUPACName: erbium. Canonical SMILES: [Er]. ECNumber: 231-160-1. Catalog: ACM7440520. | |
| Erbium(3+):triacetate:tetrahydrate | Erbium Complexes. Alternative Names: Erbium, tris(acetato-κO)tetraaqua-. CAS No. 1137599-15-5. Molecular formula: C6H17ErO10. Mole weight: 416.45. Purity: 98%+. Catalog: ACM1137599155. | |
| Erbium Acetate | ERBIUM ACETATE, TETRAHYDRATE, 99.9% pure, -6 mesh, Formula: Er(OOCCH3)3.4H2O. CAS No. 15280-57-6. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! |  Texas TX |
| Erbium Acetate | Erbium Acetate. Grades: 99.99% Extremely High (>=99%). CAS No. 15280-57-6. Pack Sizes: Gram Quantities: 50 gm, 100 gm. Order Number: 1684. |  www.prochemonline.com |
| Erbium Aluminide | Erbium Aluminide is generally immediately available in most volumes. HHigh purity, submicron and nanopowder forms may be considered. Group: Er. CAS No. 12004-20-5. Molecular formula: ErAl2. Mole weight: 221g/mol. Appearance: solid. Catalog: ACM12004205. | |
| Erbium Arsenide | Erbium Arsenide is a crystalline solid used as a semiconductor and in photo optic applications. Group: Heterocyclic organic compound. Alternative Names: Erbium arsenide, Erbium arsenide (ErAs), CID82998, EINECS 235-501-5, 12254-88-5. CAS No. 12254-88-5. Molecular formula: ErAs. Mole weight: 242g/mol. Appearance: solid. Purity: 0.96. IUPACName: arsanylidyneerbium. Catalog: ACM12254885. | |
| Erbium Barium Copper Oxide | Erbium Barium Copper Oxide is a hHigh-TC superconducting ceramic in the family of rare-earth doped barium copper oxides (or barium cuprates). Group: Er. CAS No. 109457-23-0. Molecular formula: ErBa2Cu3Ox. Mole weight: 745g/mol. Appearance: White powder or sputtering target. Catalog: ACM109457230. | |
| Erbium Bismuthide | Erbium Bismuthide is a semiconducting crystal used in photonics and other applications. Group: Ho. CAS No. 12232-90-5. Molecular formula: ErBi. Mole weight: 376g/mol. Appearance: Crystalline solid. Catalog: ACM12232905. | |
Our database is helping our users find suppliers everyday.
