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| Product | Description | |
|---|---|---|
| Ericin A | Ericin A is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria. |  |
| Ericin S | Ericin S is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria. | |
| Erigeroside | Erigeroside. Group: Biochemicals. Alternative Names: 4-Pyrone-3-beta-D-glucopyranoside. Grades: Plant Grade. CAS No. 59219-76-0. Pack Sizes: 10mg. Molecular Formula: C11H14O8, Molecular Weight: 274.223999999999. US Biological Life Sciences. |  Worldwide |
| Erinacine A | Erinacine A, derived from the Lion's Mane mushroom (Hericium erinaceus), is a bioactive compound with demonstrated anticancer, antitumor, and neuroprotective properties. It induces cancer cell death through the generation of reactive oxygen species (ROS) and is believed to modulate signaling pathways involved in cancer cell apoptosis. Additionally, Erinacine A exhibits neuroprotective effects against neurodegenerative diseases such as Parkinson's and Alzheimer's, potentially mitigating related pathological symptoms. Synonyms: Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, (3aR,5aR,6S)-; (3aR,5aR,6S)-2,3,3a,4,5,5a,6,7-Octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)cyclohept[e]indene-8-carboxaldehyde; Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, [3aR-(3aα,5aβ,6α)]-; (+)-Erinacin A; Erinacin A; (3aR,5aR,6S)-3a,5a-Dimethyl-1-(propan-2-yl)-6-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2H,3H,3aH,4H,5H,5aH,6H,7H-cyclohepta[e]indene-8-carbaldehyde; (3aR,5aR,6S)-8-Formyl-1-isopropyl-3a,5a-dimethyl-2,3,3a,4,5,5a,6,7-octahydrocyclohepta[e]inden-6-yl β-D-xylopyranoside. Grade: ≥95% by HPLC. CAS No. 156101-08-5. Molecular formula: C25H36O6. Mole weight: 432.55. | |
| Erinacine C | Erinacine C is a bioactive compound derived from the Hericium erinaceus mushroom, known for its potential neuroprotective properties. It is a cyathane diterpenoid with a unique chemical structure that has been studied for its ability to stimulate the synthesis of nerve growth factor (NGF), which can be beneficial in treating nervous system diseases such as Alzheimer's. Synonyms: β-D-Xylopyranose, 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-; 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-Decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-β-D-xylopyranose; β-D-Xylopyranose, 1,2-O-[2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-, [3aR-(3aα,5aβ,6α,7β,10aα)]-; Erinacin C. Grade: ≥95% by HPLC. CAS No. 156101-09-6. Molecular formula: C25H38O6. Mole weight: 434.57. | |
| Erinacine E | Erinacine E is a k opioid receptor agonist produced by Hericium ramosum CL24240. Synonyms: (-)-Erinacine E. Molecular formula: C25H36O6. Mole weight: 432.55. | |
| Eriobrucinol methyl ether | Eriobrucinol methyl ether. Synonyms: 1H,7H-4,6-Dioxacyclobut[1,7]indeno[5,6-b]naphthalen-7-one, 1a,2,3,3a,10b,10c-hexahydro-10-methoxy-1,1,3a-trimethyl-, [1aR-(1aα,3aα,10bα,10cα)]-. CAS No. 42259-10-9. Molecular formula: C20H22O4. Mole weight: 326.39. | |
| Eriocalyxin B | Eriocalyxin B, isolated from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor. Eriocalyxin B inhibited the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein. eriocalyxin B reversibly interfered with the binding of p65 and p50 subunits to the DNA in a noncompetitive manner. Eriocalyxin B exerts potent antiinflammatory effects through selective modulation of pathogenic Th1 and Th17 cells by targeting critical signaling pathways. Besides, Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways. Eriocalyxin B should be considered a candidate for pancreatic cancer treatment. Uses: Antiinflammatory. Synonyms: Rabdosianone. Grade: >98%. CAS No. 84745-95-9. Molecular formula: C20H24O5. Mole weight: 344.4. | |
| Eriochrome Black A | Eriochrome Black A. Group: Biochemicals. Alternative Names: 1-Naphthalene sulfonic acid. Grades: Highly Purified. CAS No. 3618-58-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Eriochrome Black T | Eriochrome Black T. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC7223, 1787-61-7, 3-Hydroxy-4-((1-hydroxy-2-naphthyl)diazenyl)-7-(hydroxy(oxido)amino)-1-naphthalenesulfonic acid. Product Category: Acid Dyes. Appearance: black powder. CAS No. 1787-61-7. Molecular formula: C20H12N3NaO7S. Mole weight: 461.38. Purity: ACS. IUPACName: 4-[(1-hydroxynaphthalen-2-yl)hydrazinylidene]-7-nitro-3-oxonaphthalene-1-sulfonic acid. Density: 1.109 g/mL at 25 °C. Product ID: ACM1787617. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Eriochrome Black T (C.I. 14645) | 25g Pack Size. Group: Stains & Indicators. Formula: C20H12N3NaO7S. CAS No. 1787-61-7. Prepack ID 51499212-25g. Molecular Weight 461.38. See USA prepack pricing. |  |
| Eriochrome black T, Indicator | Eriochrome black T indicator (C.I. 14645), 1% solid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1787-61-7. Pack Sizes: 5 g; 25 g. Product ID: HY-W110910. |  |
| Eriochrome Blue Black R | Eriochrome Blue Black R. Group: Biochemicals. Alternative Names: Mordant Black 17; CI 1575. Grades: Highly Purified. CAS No. 2538-85-4. Pack Sizes: 1kg. US Biological Life Sciences. | Worldwide |
| Eriochrome Blue Black R ≥72% (Dye content) | Eriochrome Blue Black R ≥72% (Dye content). Group: Biochemicals. Grades: Reagent Grade. CAS No. 2538-85-4. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eriochrome cyanine R | 100g Pack Size. Group: Stains & Indicators. Formula: C23H15Na3O9S. CAS No. 3564-18-9. Prepack ID 53361433-100g. Molecular Weight 536.4. See USA prepack pricing. | |
| Eriochrome Cyanine R | Eriochrome Cyanine R. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eriochrome® Cyanine R | Eriochrome® Cyanine R. Group: Biochemicals. Grades: Highly Purified. CAS No. 3564-18-9. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C23H15Na3O9S. US Biological Life Sciences. | Worldwide |
| Eriocitrin | Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria [1] [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13463-28-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0636. | |
| Eriodermin | It is a dichlorodepsidone from the lichen erioderma physcioides. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-4-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-; 2,8-dichloro-9-hydroxy-3-methoxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; 4-formyl-2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyldi-benzo[b,e][1,4]dioxepin-11-one; Eriodermine. CAS No. 92070-80-9. Molecular formula: C17H12Cl2O6. Mole weight: 383.18. | |
| Eriodictyol | analytical standard. Group: Natural compounds. |  |
| Eriodictyol | Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC 50 of 18 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Huazhongilexone. CAS No. 552-58-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N0637. | |
| Eriodictyol | Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-3',4',5,7-Tetrahydroxyflavanone. Product Category: Inhibitors. Appearance: White solid. CAS No. 552-58-9. Molecular formula: C12H21NO8S. Mole weight: 339.36. Purity: 0.99. IUPACName: (2S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one. Canonical SMILES: C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O. Density: 1.336±0.06 g/cm³. Product ID: ACM552589. Alfa Chemistry ISO 9001:2015 Certified. | |
| Eriodictyol | Eriodictyol is a natural flavonoid found in the fruits of Citrus sinensis (L.) Osbeck. Eriodictyol exhibits activities of antidiabetic, anti-inflammatory and antioxidant. Eriodictyol can increases glucose uptake and improves insulin resistance. Synonyms: (S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 3',4',5,7-tetrahydroxyflavanone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-. Grade: >97%. CAS No. 552-58-9. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Eriodictyol | Eriodictyol is a flavanone characteristic of lime, found mainly in juice. The glycosylated forms are eriocitrin (bound to a rutinoside) and neoeriocitrin (bound to a neohesperidose). Eriodictyol prevents some secondary effects of diabetes, such as diabetic retinopathy and biochemical changes in plasma (study in rats) (Bucolo et al., 2012). In addition, it has been reported that in in vitro studies, eriodictyol decreases insulin resistance and glucose absorption.Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic. Group: Biochemicals. Alternative Names: (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 3',4',5,7-tetrahydroxy-flavanone; (+)-Eriodictyol; (2S)-Eriodictyol; (S)-3',4',5,7-Tetrahydroxyflavanone; 3',4',5,7-Tetrahydroxyflavanone; Huazhongilexone. Grades: Highly Purified. CAS No. 552-58-9. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological Life Sciences. | Worldwide |
| Eriodictyol 7,3'-dimethyl ether | Eriodictyol 7,3'-dimethyl ether is a natural compound isolated from the herbs of Blumea balsamifera. Synonyms: (2S)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one. Grade: 98.0%. CAS No. 54352-60-2. Molecular formula: C17H16O6. Mole weight: 316.30. | |
| Eriodictyol 7-O-glucoside | Eriodictyol 7-O-glucoside is isolated from the herbs of Dracocephalum rupestre. It has protective effect on cisplatin-induced toxicity. Synonyms: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one; eriodictyol-7-glucoside. Grade: 95%. CAS No. 38965-51-4. Molecular formula: C21H22O11. Mole weight: 450.39. | |
| Eriodictyol-7-O-glucoside | Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Eriodictyol 7-O-β-D-glucoside. CAS No. 38965-51-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N3847. | |
| Eriodictyol chalcone | Eriodictyol chalcone possesses both anti-aromatase and anti-17β-HSD activity. Synonyms: 2',3,4,4',6'-Pentahydroxychalcone; 3,4,2',4',6'-Pentahydroxychalcone. CAS No. 14917-41-0. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Erioglaucine ≥85% (Dye content) | Erioglaucine ≥85% (Dye content). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| ERIO GREEN B | ERIO GREEN B. Uses: Designed for use in research and industrial production. Product Category: Acid Dyes. CAS No. 12768-78-4. Molecular formula: C31H33N2NaO6S2. Mole weight: 560.61. Product ID: ACM12768784. Alfa Chemistry ISO 9001:2015 Certified. | |
| Eriosema Psoraleoides Powder | Eriosema Psoraleoides Powder. |  CA, FL & NJ |
| Eriostemoic acid | Eriostemoic acid. Synonyms: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-6-propionic acid, 5-methoxy-2,2,8,8-tetramethyl- (7CI,8CI); 5-Methoxy-2,2,8,8-tetramethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-6-propanoic acid. CAS No. 26535-36-4. Molecular formula: C20H24O5. Mole weight: 344.4. | |
| Erismodegib | Erismodegib. Group: Biochemicals. Alternative Names: rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225. Grades: Highly Purified. CAS No. 956697-53-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H26F3N3O3. US Biological Life Sciences. | Worldwide |
| Eritadenine | Eritadenine (Lentinacin) is a S-adenosyl-L-homocysteine hydrolase ( SAHH ) inhibitor. Eritadenine can be found in secondary metabolites of shiitake mushrooms. Eritadenine lowers blood cholesterol levels and can be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lentinacin; D-Eritadenine; Lentysine. CAS No. 23918-98-1. Pack Sizes: 1 mg. Product ID: HY-114866. | |
| Eritadenine | Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma. Group: Biochemicals. Alternative Names: (αR, βR)-6-Amino-α, β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; D-Eritadenine. Grades: Highly Purified. CAS No. 23918-98-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Eritadenine Acetonide | Eritadenine Acetonide is an intermediate in the synthesis of Eritadenine, which is an inhibitor of S-adenosine-L-homocysteine hydrolase (SAHH) with hypocholesterolemic activity. Synonyms: (4R-cis)-5-[(6-Amino-9H-purin-9-yl)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylic Acid; D-4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-erythronic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 1,3-Dioxolane-4-carboxylic acid, 5-[(6-amino-9H-purin-9-yl)methyl]-2,2-dimethyl-, (4R-cis)-. CAS No. 29031-25-2. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| Eritoran | Eritoran is a TLR4 antagonist that is developed for the treatment of severe sepsis. Synonyms: ERITORAN; 185955-34-4; Eritoran [INN]; E5564; CHEMBL501259; [(2R,3R,4R,5S,6R)-4-decoxy-5-hydroxy-6-[[(2R,3R,4R,5S,6R)-4-[(3R)-3-methoxydecoxy]-6-(methoxymethyl)-3-[[(Z)-octadec-11-enoyl]amino]-5-phosphonooxyoxan-2-yl]oxymethyl]-3-(3-oxotetradecanoylamino)oxan-2-yl] dihydrogen phosphate; CHEBI:68609; 551541VI0Y; 3-O-decyl-2-deoxy-6-O-(2-deoxy-3-O-(3-methoxydecyl)-6-O-methyl-2-((1-oxo-11-octadecenyl. Grade: 95%. CAS No. 185955-34-4. Molecular formula: C66H126N2O19P2. Mole weight: 1313.66. | |
| Eritoran | Eritoran is a Toll-like receptor 4 (TLR4) antagonist. Eritoran protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran inhibits pathogenesis of filovirus infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ERITORAN;3-O-Decyl-2-deoxy-6-O-[2-deoxy-3-O-[(3R)-3-methoxydecyl]-6-O-methyl-2-[[(11Z)-1-oxo-11-octadecenyl]amino]-4-O-phosphono-beta-D-glucopyranosyl]-2-[(1,3-dioxotetradecyl)amino]-alpha-D-glucopyranose 1-(dihydrogen phosphate);Eritoran [inn]. Product Category: Inhibitors. CAS No. 185955-34-4. Molecular formula: C66H122N2O19P2.4Na. Mole weight: 1401.59. Density: 1.14. Product ID: ACM185955344. Alfa Chemistry ISO 9001:2015 Certified. | |
| ERK1/2 inhibitor 1 | ERK1/2 inhibitor 1 is a potent and orally bioavailable ERK1/2 inhibitor, inhibiting ERK1 up to 60% at 1 nM and inhibiting ERK2 with an IC50 of 3.0 nM. Synonyms: 2H-Isoindole-2-acetamide, 6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-1,3-dihydro-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]-α-methyl-1-oxo-, (αR)-; (2R)-2-{6-[5-Chloro-2-(tetrahydro-2H-pyran-4-ylamino)-4-pyrimidinyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]propanamide. Grade: ≥95%. CAS No. 2095719-90-5. Molecular formula: C29H32ClN5O4. Mole weight: 550.05. | |
| ERK1/2 inhibitor 1 | ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095719-90-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112287. | |
| ERK1/2 inhibitor 3 | ERK1/2 inhibitor 3, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2021218912A1, compound 1). Synonyms: (S)-2-(6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-1,1-dioxidobenzo[d]isothiazol-2(3H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide. CAS No. 2737294-99-2. Molecular formula: C28H31ClFN5O6S. Mole weight: 620.09. | |
| ERK1/2 inhibitor 4 | ERK1/2 inhibitor 5, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2020238776A1). Synonyms: Thieno[3,2-c]pyridine-5(4H)-acetamide, 2-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-6,7-dihydro-α-methyl-4-oxo-, (αR)-. CAS No. 2490396-99-9. Molecular formula: C28H31ClFN5O5S. Mole weight: 604.09. | |
| ERK1/2 inhibitor 6 | ERK1/2 inhibitor 6, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2021063335A1, compound 1). Synonyms: (R)-2-(6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-4-oxopyrrolo[2,1-f][1,2,4]triazin-3(4H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide. CAS No. 2634816-13-8. Molecular formula: C27H29ClFN7O5. Mole weight: 586.01. | |
| ERK1, active, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ERK1, active, untagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ERK2, active, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ERK2 IN-1 | ERK2 IN-1 is a selective inhibitor of ERK2 with an IC50 of 7 nM. Synonyms: (3S)-N-[3-(4-Fluorophenyl)-1H-indazol-5-yl]-3-(methylsulfanyl)-1-(2-oxo-2-{4-[4-(2-pyrimidinyl)phenyl]-3,6-dihydro-1(2H)-pyridinyl}ethyl)-3-pyrrolidinecarboxamide; 3-Pyrrolidinecarboxamide, 1-[2-[3,6-dihydro-4-[4-(2-pyrimidinyl)phenyl]-1(2H)-pyridinyl]-2-oxoethyl]-N-[3-(4-fluorophenyl)-1H-indazol-5-yl]-3-(methylthio)-, (3S)-. Grade: ≥95%. CAS No. 1093061-47-2. Molecular formula: C36H34FN7O2S. Mole weight: 647.76. | |
| ERK5, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ERK5-IN-1 | ERK5-IN-1 is a potent ERK5 inhibitor with an IC50 of 87±7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC50 of 26 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1234479-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14403. | |
| ERK5-IN-2 | ERK5-IN-2 is a submicromolar selective ERK5 inhibitor with oral activity, which can inhibit tumor xenograft growth and basic fibroblast growth factor (bFGF)-driven Matrigel plug angiogenesis. Synonyms: 4-(2-Bromanyl-6-Fluoranyl-Phenyl)Carbonyl-{N}-Pyridin-3-Yl-1{H}-Pyrrole-2-Carboxamide; SCHEMBL17607180; BCP32587; EX-A4938. Grade: 98%. CAS No. 1888305-96-1. Molecular formula: C17H11BrFN3O2. Mole weight: 388.2. | |
| ERK5-IN-2 | ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 ?M, 3 ?M for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1888305-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128341. | |
| ERK5-IN-5 | ERK5-IN-5 (compound 4a) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-5 exhibits good anti-proliferative activity with the IC 50 value of 6.23 μg/mL for A549 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2318792-30-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156450. | |
| ERK Activation Inhibitor Peptide I, Cell-Permeable | The ERK Activation Inhibitor Peptide I, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| ERK Activation Inhibitor Peptide II, Cell-Permeable | The ERK Activation Inhibitor Peptide II, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| ERK-IN-2 | ERK-IN-2, an ERK2 inhibitor probe (IC50 = 1.8 nM), may cause off-target toxicity and/or off-target activity at doses >10 μM. Synonyms: 1-[4-(Hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1R)-1-phenylethyl]urea hydrochloride (1:1); Urea, N-[4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-N'-[(1R)-1-phenylethyl]-, hydrochloride (1:1). Grade: ≥95%. Molecular formula: C16H18ClN5O2. Mole weight: 347.80. | |
| ERK-IN-3 | ERK-IN-3 is a potent and orally active ERK inhibitor that can be used in cancer research caused by RAS mutations. It inhibits ERK1/2 with low single-digit nM IC50 values. Synonyms: N-[(1S)-2-amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-{5-methyl-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1H-imidazole-4-carboxamide; ASN007 free base; NSC-828319; N-[(1S)-2-Amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-[5-methyl-2-(tetrahydro-2H-pyran-4-ylamino)-4-pyrimidinyl]-1H-imidazole-4-carboxamide. Grade: ≥99%. CAS No. 2055597-12-9. Molecular formula: C22H25ClFN7O2. Mole weight: 473.93. | |
| ERK-IN-3 benzenesulfonate | ERK-IN-3 benzenesulfonate is a potent and orally active ERK inhibitor that can be used in cancer research caused by RAS mutations. It inhibits ERK1/2 with low single-digit nM IC50 values. Synonyms: 1H-Imidazole-4-carboxamide, N-[(1S)-2-amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-[5-methyl-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-, compd. with benzenesulfonate (1:1). Grade: ≥98%. CAS No. 2055597-39-0. Molecular formula: C28H31ClFN7O5S. Mole weight: 632.11. | |
| ERK Inhibitor | ERK inhibitor, a reversible thiazolidinedione compound, is a cell-permeable inhibitor that binds ERK2 near its docking domain with a KD of 5 μM and prevents its interaction with protein substrates. Synonyms: Extracellular Regulated Kinase Inhibitor; 3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylene]-2,4-thiazolidinedione, monohydrochloride. Grade: ≥95%. CAS No. 1049738-54-6. Molecular formula: C14H16N2O3S·HCl. Mole weight: 328.8. | |
| ERK Inhibitor - CAS 1049738-54-6 | The ERK Inhibitor, also referenced under CAS 1049738-54-6, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| ERK Inhibitor II, FR180204 - CAS 865362-74-9 | ERK Inhibitor II, FR 180204, CAS 865362-74-9, is a cell-permeable, potent, ATP-competitive inhibitor of ERK1 and ERK2 (IC?? = 510 nM and 330 nM; Ki = 310 nM and 140 nM, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| ERK Inhibitor III - CAS 331656-92-9 | The ERK Inhibitor III, also referenced under CAS 331656-92-9, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| ERK Inhibitor II, Negative Control, FR180209 - CAS 1177970-73-8 | The ERK Inhibitor II, Negative Control, also referenced under CAS 1177970-73-8, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| ERK Inhibitor VIII ((S)-4-(2-(2-Chloro-4-fluorophenylamino)-5-methylpyrimidin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide) | A cell-permeable pyrimidylpyrrole compound that acts as an active site-targeting, highly potent and selective ERK1/2 inhibitor (KI <2nM against Erk2; [ATP] = 65uM), while inhibiting GSK-3, Aurora A, Cdk2 only at much higher concentrations (KI = 395, 540, and 852nM, respectively) and exhibiting much reduced or little potency toward a panel of more than 130 other kinases (KI ≥1.4uM; IC50 ≥1uM). Shown to effectively inhibit human colon carcinoma HT-29 proliferation (IC50 = 48nM) and restore EGFR inhibitor WZ4002 antiproliferation activity in WZR10 cultures (84% and no inhibition, respectively, by 100nM WZ4002 with or without 1uM Erk Inhibitor VIII co-treatment). Orally available in both mice and rats in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 896720-20-0. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?FN?O?. US Biological Life Sciences. | Worldwide |
| Erlizumab | Erlizumab is a humanized monoclonal antibody that targets CD18. Erlizumab has been investigated as a therapy for hemorrhagic shock. Synonyms: rhuMAb. Grade: 95%. CAS No. 211323-03-4. | |
| Erlose | Erlose is a widely utilized pharmaceutical in the biomedical sector, serving as a prominent role for studying Type 2 diabetes. Its mechanism of action entails augmenting glycemic regulation while concurrently amplifying the responsiveness of cells towards insulin. Synonyms: a-D-Glc-(1→4)-a-D-Glc-(1→2)-b-D-Fru; a-Maltosyl b-fructofuranoside; β-D-Fructofuranosyl O-α-D-glucopyranosyl-(1→4)-α-D-glucopyranoside; Fructomaltose. CAS No. 13101-54-7. Molecular formula: C18H32O16. Mole weight: 504.44. | |
| Erlosiban | Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour. Synonyms: UOBE-001; OBE001; OBE001; NII-3765U8A1EC; CHEMBL1254025; 3765U8A1EC; Erlosiban; Erlosiban [INN]; [(2S,4Z)-2-(hydroxymethyl)-4-methoxyiminopyrrolidin-1-yl]-[4-(2-methylphenyl)phenyl]methanone. Grade: 98%. CAS No. 1477482-19-1. Molecular formula: C20H22N2O3. Mole weight: 338.41. | |
| Erlotinib | Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC 50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC 50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer [1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-358774; NSC 718781; OSI-774. CAS No. 183321-74-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-50896. | |
| Erlotinib | Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy. Synonyms: CP358774; CP 358774; CP-358774; NSC 718781; NSC718781; NSC-718781. Grade: >98%. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44. | |
| Erlotinib-[13C6] Hydrochloride | Erlotinib-[13C6] Hydrochloride is the labelled salt of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: Erlotinib-13C6 Hydrochloride; N-[3-ethynyl(1,2,3,4,5,6-13C6)phenyl]-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride; Tarceva-13C6. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1210610-07-3. Molecular formula: C16[13C]6H23N3O4.HCl. Mole weight: 435.82. | |
| Erlotinib-3-vinyl Hydrochloride | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine hydrochloride; 4-Quinazolinamine, N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1). Grade: 95%. CAS No. 1624294-38-7. Molecular formula: C22H26ClN3O4. Mole weight: 431.91. | |
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