A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Gallium Phosphide (GaP) Semiconductor Crystal. Group: Magnetic nanoparticles. Alternative Names: GaP Wafers, GaP Substrate, GaP Slice, Gallium Phosphide Wafers, Gallium Phosphide Substrate, Gallium Phosphide Slice.
Gallocatechin gallate (GCG). Group: Biochemicals. Alternative Names: (-)-Gallocatechin gallate; GCG. Grades: Plant Grade. CAS No. 4233-96-9. Pack Sizes: 20mg. Molecular Formula: C22H18O11, Molecular Weight: 458.372. US Biological Life Sciences.
Worldwide
Gallocyanine
Gallocyanine. Group: Biochemicals. Alternative Names: Mordant Blue 1; CI 513; 7-Dimethylamino-4-hydroxy-3-oxo-3H-phenoxazine-1-carboxylic acid. Grades: Highly Purified. CAS No. 1562-85-2. Pack Sizes: 50g, 100g. US Biological Life Sciences.
Worldwide
Gallocyanine
Gallocyanine belongs to the oxazine class of dyes and is often used to stain animal cells, mostly the nucleic acids. Gallocyanine is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Synonyms: IIIC3; Alizarine Navy Blue; Anthracene Blue SWGG; Brilliant Chrome Blue P; C.I. 51030; Fast Violet; Mordant Blue 10; 7-Dimethylamino-4-hydroxy-3-oxo-phenoxazine-1-carboxylic acid. Grades: ≥95%. CAS No. 1562-85-2. Molecular formula: C15H13N2O5·Cl. Mole weight: 336.7.
Gallocyanine chloride
Gallocyanine chloride, a synthetic blue dyestuff, blocks DKK1 inhibitory activity by disrupting DKK1/LRP6 interaction. Its association with LRP6 is weak (IC 50 of about 3 μM in the inhibition of DKK1 binding). Gallocyanine dye acts as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1562-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0961.
Galloflavin
Galloflavin is a potent lactate dehydrogenase (LDH) inhibitor. The calculated K i s for pyruvate are 5.46 μM (LDH-A) and 15.06 μM (LDH-B). Galloflavin hinders the proliferation of cancer cells by blocking glycolysis and ATP production [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 568-80-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W040118.
Galloflavin
Galloflavin. Group: Biochemicals. Alternative Names: 3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione; NSC 107022. Grades: Highly Purified. CAS No. 568-80-9. Pack Sizes: 10mg. Molecular Formula: C12H6O8, Molecular Weight: 278.17. US Biological Life Sciences.
Worldwide
Galloflavin
Galloflavin is a novel inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 μM, respectively). It has also been shown to be a potential anticancer agent. Synonyms: NSC 107022; 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione. Grades: ≥98%. CAS No. 568-80-9. Molecular formula: C12H6O8. Mole weight: 278.2.
Galloflavin Potassium salt
Galloflavin Potassium salt is an inhibitor of human lactate dehydrogenase (LDH) (Ki = 5.46 and 15.1 μM for LDH-A and LDH-B, respectively, in competition with pyruvate) with anticancer activity. Galloflavin inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells. Synonyms: NSC-107022 potassium; NSC 107022 potassium; NSC107022 potassium; 3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione potassium salt. Grades: ≥95% by HPLC. CAS No. 1780260-20-9. Molecular formula: C12H5O8K. Mole weight: 316.26.
Gallopamil hydrochloride
Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist [1]. Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC 50 of 10.9 μM [2]. Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methoxyverapamil hydrochloride. CAS No. 16662-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-14276A.
Galloylpaeoniflorin
Galloylpaeoniflorin. Group: Biochemicals. CAS No. 122965-41-7. Pack Sizes: 5mg. US Biological Life Sciences.
Isolated from the bacterium Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. Group: Enzymes. Synonyms: PglI. Enzyme Commission Number: EC 2.4.1.293. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2527; GalNAc5-diNAcBac-PP-undecaprenol β-1,3-glucosyltransferase; EC 2.4.1.293; PglI. Cat No: EXWM-2527.
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. Group: Enzymes. Synonyms: PglH. Enzyme Commission Number: EC 2.4.1.292. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2526; GalNAc-α-(1?4)-GalNAc-α-(1?3)-diNAcBac-PP-undecaprenol α-1,4-N-acetyl-D-galactosaminyltransferase; EC 2.4.1.292; PglH. Cat No: EXWM-2526.
GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP
GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is a crucial compound extensively used in the biomedical industry for studying glycosidase-related diseases. It acts as a substrate for enzymes involved in research of lysosomal storage disorders such as Tay-Sachs disease and Gaucher disease. Molecular formula: C32H48N20O23. Mole weight: 1080.84.
GalNAc-C3-CPG, a novel therapeutic agent, holds significant potential in the fight against viral infections. Its innovative and intricate architecture aptly mimics viral RNA, thereby facilitating the activation of the immune system and a consequential robust antiviral response. Synonyms: (4- (Trimethoxytrityloxymethyl) -1- (6- (4- (3, 4, 6-O-triacetyl-2-acetylamino-2-deoxy-β -D-galactopyranosyl) butanamido) hexanoyl) piperidin-4-yl) methyl-O-succinoyl CPG.
GalNAc-INF7
GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Synonyms: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78.
GalNAc trimer-Cy5.5
GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. Cy5.5 (Cyanine-5.5) is a cyanine dye. Synonyms: GalNAc trimer-Cyanine5.5. Molecular formula: C112H172N13O33. Mole weight: 2228.63.
Galnon
Galnon. Group: Biochemicals. Grades: Purified. CAS No. 475115-35-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Galnon
Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Synonyms: 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide; L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Fmoc-b-cyclohexyl-Ala-Lys-AMC. Grades: ≥95% by HPLC. CAS No. 475115-35-6. Molecular formula: C40H46N4O6. Mole weight: 678.83.
Galunisertib
Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells. Synonyms: LY 2157299; LY-2157299; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grades: >98%. CAS No. 700874-72-2. Molecular formula: C22H19N5O. Mole weight: 369.428.
Gamabufotalin. Group: Biochemicals. Alternative Names: Gamabufagin; Gamabufogenin. Grades: Plant Grade. CAS No. 465-11-2. Pack Sizes: 20mg. Molecular Formula: C24H34O5, Molecular Weight: 402.524. US Biological Life Sciences.
Worldwide
Gamabufotalin
Gamabufotalin is a major bufadienolide of Chansu and has been used for cancer therapy due to its desirable metabolic stability and less adverse effect. Uses: Strong heart, antitumor. Synonyms: Gamabufagin. Grades: >98%. CAS No. 465-11-2. Molecular formula: C24H34O5. Mole weight: 402.52.
Gama-Hydroxy Baclofen
Gama-Hydroxy Baclofen is the impurity of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Molecular formula: C10H12ClNO3. Mole weight: 229.66.
Gambierol
It is produced by the strain of Gambierdiscus toxicus. Gambierol is the substance that causes ciguatera poisoning (severe diarrhea, perceptual abnormalities, etc.). Synonyms: (-)-Gambierol. Grades: 99%. CAS No. 146763-62-4. Molecular formula: C43H64O11. Mole weight: 756.96.
Gambogenic acid
Gambogenic Acid is a natural compound isolated from Garcinia hanburyi Hook. f. It shows anticancer activity. Grades: 98%. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.8.
Gambogenic Acid
Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination. Group: Inhibitors. Alternative Names: (2Z)-4-[(1R,3aS,5S,12aS)-9-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-2-methyl-2-butenoic acid. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.77. Appearance: Brownish red powder. Purity: 0.98. IUPACName: (Z)-4-[(1S, 2S, 13S, 15R)-7-[(2E)-3, 7-dimethylocta-2, 6-dienyl]-6, 8-dihydroxy-17, 17-dimethyl-5-(3-methylbut-2-enyl)-10, 14-dioxo-3, 16-dioxapentacyclo[11.4.1.02, 11.02, 15.04, 9]octadeca-4, 6, 8, 11-tetraen-15-yl]-2-methylbut-2-enoic acid. Canonical SMILES: CC (=CCC/C (=C/CC1=C (C (=C2C (=C1O)C (=O)C3=C[C@@H]4C[C@@H]5[C@@]3 (O2)[C@] (C4=O) (OC5 (C)C)C/C=C (/C)\C (=O)O)CC=C (C)C)O)/C)C. Density: 1.27±0.1 g/ml. Catalog: ACM173932757.
Gambogic acid
Gambogic acid is a natural product inhibitor of Hsp90. Synonyms: B-Guttiferrin; Beta-Guttiferrin; Beta-Guttilactone; Cambogic acid; Guttatic acid; Guttic acid. Grades: >95%. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.76.
Gambogic Acid
Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Group: Inhibitors. Alternative Names: β-Guttilactone. CAS No. 2752-65-0. Molecular formula: C38H44O8. Mole weight: 628.75. Appearance: Yellow powder. Purity: 0.98. IUPACName: (Z)-4-[(1S, 2S, 8R, 17S, 19R)-12-hydroxy-8, 21, 21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14, 18-dioxo-3, 7, 20-trioxahexacyclo[15.4.1.02, 15.02, 19.04, 13.06, 11]docosa-4(13), 5, 9, 11, 15-pentaen-19-yl]-2-methylbut-2-enoic acid. Canonical SMILES: CC (=CCC[C@@]1 (C=CC2=C (C3=C (C (=C2O1)CC=C (C)C)O[C@@]45[C@H]6C[C@@H] (C=C4C3=O)C (=O)[C@@]5 (OC6 (C)C)C/C=C (/C)\C (=O)O)O)C)C. Density: 1.11 g/ml. Catalog: ACM2752650.
Gambogic Acid
Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-X L , Bcl-2 , Bcl-W , Bcl-B , Bfl-1 and Mcl-1 with IC 50 s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Beta-Guttiferrin. CAS No. 2752-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0087.
Gambogic Acid
Gambogic Acid is an apoptosis inducer in sever tumor cell lines via regulation of Bax and inhibition of Bcl-2 genes. Induces EGFR degredation through AMPK dependant-LRIG1 upregulation in glioma cells. Apoptosis inducer in several tumor cell lines including T47D cells. Activates caspases (EC50 values are 0.78 - 1.64uM) and competitively inhibits antiapoptotic Bcl-2 family proteins (IC50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79uM for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). Reverses gefitinib-resistance in mice bearing tumors with EGFR-T790M mutation. Also blocks Kir2.1 channels (EC50 ≤100nM). Group: Biochemicals. Alternative Names: (2Z)-2-Methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-2-butenoic acid. Grades: Purified. CAS No. 2752-65-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C38H44O8, Molecular Weight: 628.75. US Biological Life Sciences.
Worldwide
Gambogic Acid Liposome
Gambogic acid (GA) is derived from the gamboge and is a protease activator and apoptosis inducer. This product is a pre-formulated liposome encapsulating Gambogic Acid. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Gambogic amide
Gambogic amide is a potent and selective agonist of TrkA and also induces its tyrosine phosphorylation and activation of downstream signaling, including Akt and MAPK. Gambogic amide specifically interacts with the cytoplasmic juxtamembrane domain of the TrkA receptor and triggers its dimerization, leading to activation. Gambogic amide has neuroprotective activity preventing glutamate-induced neuronal cell death. Gambogic amide has improved efficacy in a transient middle cerebral artery occlusion model of stroke and could be used to study neurodegenerative diseases and stroke [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286935-60-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121833.
gametolysin
A glycoprotein found in the periplasmic space of Chlamydomonas reinhardtii gametes in a 62 kDa inactive form; decreased to 60 kDa upon activation. A zinc enzyme, inhibited by phosphoramidon, but also thiol activated. Type example of peptidase family M11. Group: Enzymes. Synonyms: autolysin, Chlamydomonas cell wall degrading protease; lysin; Chlamydomonas reinhardtii metalloproteinase; gamete lytic enzyme; gamete autolysin. Enzyme Commission Number: EC 3.4.24.38. CAS No. 97089-74-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4320; gametolysin; EC 3.4.24.38; 97089-74-2; autolysin, Chlamydomonas cell wall degrading protease; lysin; Chlamydomonas reinhardtii metalloproteinase; gamete lytic enzyme; gamete autolysin. Cat No: EXWM-4320.
Gamithromycin. Group: Biochemicals. Alternative Names: (2R, 3S, 4R, 5S, 8R, 10R, 11R, 12S, 13S, 14R)-13-[(2, 6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 8, 10, 12, 14-hexamethyl-7-propyl-11-[[3, 4, 6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one; ML 1709460. Grades: Highly Purified. CAS No. 145435-72-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C40H76N2O12. US Biological Life Sciences.
Worldwide
Gamithromycin
Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML-1709460. CAS No. 145435-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108365.
Gamithromycin
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C40H76N2O12. CAS No. 145435-72-9. Prepack ID 89982152-1g. Molecular Weight 777.04. See USA prepack pricing.
Gamithromycin-d4
Isotope labelled analog of Gamithromycin, a macrolide compound which is known to have antibacterial activity, and is useful in mammals' bacterial infections treatment. Antibiotic. Synonyms: (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one; ML 1709460-d5. Grades: 95%. Molecular formula: C40H71D5N2O12. Mole weight: 782.08.
Gamithromycin-d4 (Major)
Isotope labelled analog of Gamithromycin (G195000), a macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic. Group: Biochemicals. Alternative Names: (2R, 3S, 4R, 5S, 8R, 10R, 11R, 12S, 13S, 14R)-13-[(2, 6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 8, 10, 12, 14-hexamethyl-7-propyl-11-[[3, 4, 6-trideoxy-3-(dimethylamino)- β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one; ML 1709460-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gamithromycin Impurity 1
Gamithromycin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 145388-07-4. Molecular Formula: C37H70N2O12. Mole Weight: 734.97. Catalog: APB145388074.
Gamithromycin Impurity 2
Gamithromycin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 145414-17-1. Molecular Formula: C37H66N2O12. Mole Weight: 730.94. Catalog: APB145414171.