A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ganetespib, also known as STA-9090, is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor STA-9090 binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c-Kit, EGFR, and Bcr-Abl, which as client proteins depend on functional Hsp90 for maintenance. Hsp90, a 90 kDa molecular chaperone upregulated in a variety of tumor cells, plays a key role in the conformational maturation, stability and function of "client" proteins within the cell, many of which are involved in signal transduction, cell cycle regulation and apoptosis, including kinases, transcription factors and hormone receptors. Hsp72 exhibits anti-apoptotic functions; its up-regulation may be used as a surrogate marker for Hsp90 inhibition. Synonyms: STA-9090; STA 9090; STA9090. Grades: >98%. CAS No. 888216-25-9. Molecular formula: C20H20N4O3. Mole weight: 364.40.
ganglioside galactosyltransferase
The substrate is also known as gangloside GM2, the product as gangloside GM1a. Group: Enzymes. Synonyms: UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase;. Enzyme Commission Number: EC 2.4.1.62. CAS No. 37217-28-0. Galactosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2605; ganglioside galactosyltransferase; EC 2.4.1.62; 37217-28-0; UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase; UDP-galactose-GM2 galactosyltransferase; uridine diphosphogalactose-GM2 galactosyltransferase; uridine diphosphate D-galactose:glycolipid galactosyltransferase; UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase; UDP-galactose-GM2 ganglioside galactosyltransferase; GM1-synthase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine β-1,3-D-galactosyltransferase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-(1?4)-β-D-glucosyl-N-acylsphingosine 3-β-D-galactosyltransferase. Cat No: EXWM-2605.
Ganglioside GD1b (Porcine Brain) Triammonium salt, a crucial glycosphingolipid, exerts vital influence over cell signaling and adhesion in the human body. Given its emerging therapeutic implications in treating neurological ailments like Parkinson's disease and multiple sclerosis, and certain cancers, it remains the focus of extensive studies. Meanwhile, its potential for modulating immune cell function in the realm of autoimmune disorders is compelling scientists to explore its promising attributes further. Synonyms: Ganglioside GD1b (porcine brain, triammonium salt). Grades: >99%. CAS No. 2315262-17-8. Molecular formula: C84H154N6O39. Mole weight: 1872.14.
Ganglioside GD3 Disodium Salt is a ligand for human noroviruses. Synonyms: Disialosyllactosylceramide Disodium Salt; GD3 Disodium Salt; Ganglioside D3 Disodium Salt. CAS No. 497932-19-1. Molecular formula: C70H123N3Na2O29. Mole weight: 1516.71.
Ganglioside GD3 Sodium Salt
Ganglioside GD3 Sodium Salt is related to Ganglioside GD3 Disodium Salt, which is a ligand for human noroviruses. Synonyms: Disialoganglioside GD3 Sodium Salt; Disialosyllactosylceramide Sodium Salt; GD3 Sodium Salt; Ganglioside D3 Sodium Salt;N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2?8)-O-(N-acetyl-α-neuraminosyl)-(2?3)-O-β-D-galactopyranosyl-(1?4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-octadecanamide Sodium Salt. Grades: 95%. Molecular formula: C70H125N3O29 xNa. Mole weight: 1472.74.
Ganglioside GM1 (Ovine Brain)
Ganglioside GM1 sodium salt is a specific and only receptor for cholera toxin which facilitates the toxin's transmembrane movement. Cells which lack Ganglioside GM1 can be toxin-resistant, further proving the role of this receptor in the cholera toxicity mechanism. Synonyms: GM1 Ganglioside (Brain, Ovine-Sodium Salt). Grades: >99%. CAS No. 37758-47-7. Mole weight: 1568.805.
Ganglioside GQ1b (Porcine Brain) Tetraammonium salt
Ganglioside GQ1b (Porcine Brain) Tetraammonium salt is an essential biomolecule found in the porcine brain. This tetraammonium salt of Ganglioside GQ1b is used for studying various neurological disorders, known for its neuroprotective properties. Synonyms: Ganglioside GQ1b (porcine brain, tetraammonium salt). Grades: >99%. CAS No. 2316360-46-8. Molecular formula: C106H194N10O55. Mole weight: 2488.73.
Gangliosides
Gangliosides is a glycosphingolipid predominantly located within the nervous system. These multifaceted compounds assume a pivotal role in facilitating intercellular exchange, governing neural growth and modulating synaptic adaptability. Synonyms: GM1, GD1a, GD1b, GT1b gangliosides, mixed ammoinum salts.
Ganglioside-Total
Total Ganglioside Extract (Brain, Porcine-Ammonium Salt). Group: Natural lipids. CAS No. 383907-71-9. Mole weight: 1563.853. Purity: >99%. Catalog: ACM383907719.
Gangliotetraose
Gangliotetraose, a biomedicine product, stands as a pivotal remedy for ganglioside deficiency ailments, such as GM2-gangliosidosis and Tay-Sachs disease. Through emulating the constituents of gangliosides found naturally, it rejuvenates their abundance and ameliorates neuronal activity. Luringly, the tantalizing prospect of neuroprotection accompanies Gangliotetraose, holding great promise in its remedial capacity for those afflicted by these incapacitating disorders. Synonyms: Asialo-GM1-tetrasaccharide; Asialo GM1 oligosaccharide. CAS No. 75645-24-8. Molecular formula: C26H45NO21. Mole weight: 707.64.
Gangliotriose
Gangliotriose is a crucial component utilized in the biomedical industry for researching various neurodegenerative diseases. Its structural similarities to gangliosides make it an ideal tool for studying drug targets associated with Alzheimer's disease, Parkinson's disease and other neurological disorders. Synonyms: Asialo-GM2-trisaccharide; N-Acetylgalactosamine b1-4 Lactose; Asialo GM2 oligosaccharide; GalNAc(b1-4)Gal(b1-4)Glc. CAS No. 1355005-58-1. Molecular formula: C20H35NO16. Mole weight: 545.49.
Ganirelix
Heterocyclic Organic Compound. Alternative Names: Ganirelix. CAS No. 123246-29-7. Molecular formula: C80H113ClN18O13. Mole weight: 1570.32. Catalog: ACM123246297.
Ganirelix
Ganirelix is a GnRH antagonist used primarily in assisted reproduction to control ovulation. It acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide; D 24598; Orgalutran; RS 26306; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-hArg(Et,Et)-Leu-hArg(Et,Et)-Pro-D-Ala-NH2. Grades: 95%. CAS No. 124904-93-4. Molecular formula: C80H113ClN18O13. Mole weight: 1570.32.
Ganirelix
Ganirelix. Categories: ganirelix; 124904-93-4.
CA, FL & NJ
Ganirelix acetate
Ganirelix acetate. Group: Biochemicals. Alternative Names: N-Acetyl-3- (2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3- (3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis (ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis (ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide. Grades: Highly Purified. CAS No. 129311-55-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C84H121ClN18O17. US Biological Life Sciences.
Worldwide
Ganirelix Acetate
Ganirelix acetate is a decapeptide GnRH antagonist. It acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. It is primarily used in assisted reproduction to control ovulation. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-hArg(Et,Et)-Leu-hArg(Et,Et)-Pro-D-Ala-NH2.2CH3CO2H; Antagon; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate; Orgalutran. Grades: 98%. CAS No. 129311-55-3. Molecular formula: C84H121ClN18O17. Mole weight: 1690.42.
Ganirelix Impurity F is an impurity of Ganirelix Acetate. Synonyms: AC-D-2-NAL-D-4-CLPHE-D-3-PAL; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanine. Grades: > 95%. CAS No. 129225-22-5. Molecular formula: C32H31ClN4O5. Mole weight: 587.08.
Ganoderal A
Terpenoids. CAS No. 104700-98-3. Molecular formula: C30H44O2. Mole weight: 436.68. Appearance: White cryst. Purity: 0.98. IUPACName: (E,6R)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]hept-2-enal. Canonical SMILES: CC (CCC=C (C)C=O)C1CCC2 (C1 (CC=C3C2=CCC4C3 (CCC (=O)C4 (C)C)C)C)C. Catalog: ACM104700983.
Ganoderal A
Ganoderal A. Group: Biochemicals. Grades: Plant Grade. CAS No. 104700-98-3. Pack Sizes: 5mg. Molecular Formula: C30H44O2, Molecular Weight: 436.68. US Biological Life Sciences.
Worldwide
Ganoderenic acid A
Ganoderenic acid A. Group: Biochemicals. CAS No. 100665-40-5. Pack Sizes: 5mg. US Biological Life Sciences.
Ganoderenic acid C. Group: Biochemicals. Grades: Plant Grade. CAS No. 100665-42-7. Pack Sizes: 5mg. Molecular Formula: C30H44O7, Molecular Weight: 516.67. US Biological Life Sciences.
Worldwide
Ganoderenic acid C
Ganoderenic acid C is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: (3β,7β,15α,20E)-3,7,15-Trihydroxy-11,23-dioxo-lanosta-8,20(22)-dien-26-oic acid. Grades: >98%. CAS No. 100665-42-7. Molecular formula: C30H44O7. Mole weight: 516.675.
Ganoderenic acid D. Group: Biochemicals. Grades: Plant Grade. CAS No. 100665-43-8. Pack Sizes: 10mg. Molecular Formula: C30H40O7, Molecular Weight: 512.64. US Biological Life Sciences.
Worldwide
Ganoderenic acid E
Ganoderenic acid E is a natural compound derived from Ganoderma lucidum that exhibits anticancer and anti-inflammatory properties. It has been shown to inhibit the growth of various cancer cells and reduce inflammation in experimental models. Grades: >98%. CAS No. 110241-23-1. Molecular formula: C30H40O8. Mole weight: 528.642.
Ganoderic Acid A. Group: Biochemicals. Alternative Names: (7 β,15α,25R)-7,15-Dihydroxy-3,11,23-trioxolanost-8-en-26-oic Acid. Grades: Highly Purified. CAS No. 81907-62-2. Pack Sizes: 1mg. Molecular Formula: C30H44O7, Molecular Weight: 516.669999999999. US Biological Life Sciences.
Worldwide
Ganoderic Acid A
Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the most well characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition. (Source: http://en. wikipedia. org/wiki/Ganoderic_acid). Group: Others. Alternative Names: (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid. CAS No. 81907-62-2. Molecular formula: C30H42O7. Mole weight: 514.65. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: C[C@H] (CC (=O)C[C@@H] (C)C (=O)O)[C@H]1C[C@@H] ([C@@]2 ([C@@]1 (CC (=O)C3=C2[C@H] (C[C@@H]4[C@@]3 (CCC (=O)C4 (C)C)C)O)C)C)O. Density: 1.22 g/ml. Catalog: ACM81907622.
Ganoderic Acid B
Ganoderic Acid B. Group: Biochemicals. Alternative Names: (3 β,7 β,25R)-3,7-Dihydroxy-11,15,23-trioxolanost-8-en-26-oic Acid. Grades: Highly Purified. CAS No. 81907-61-1. Pack Sizes: 1mg. Molecular Formula: C30H44O7, Molecular Weight: 516.669999999999. US Biological Life Sciences.
Worldwide
Ganoderic Acid B
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease. Group: Inhibitors. CAS No. 81907-61-1. Molecular formula: C30H44O7. Mole weight: 516.7. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: CC (CC (=O)CC (C)C (=O)O)C1CC (=O)C2 (C1 (CC (=O)C3=C2C (CC4C3 (CCC (C4 (C)C)O)C)O)C)C. Catalog: ACM81907611.
Ganoderic acid C2
Ganoderic acid C2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Ganoderic Acid C2 exhibits inhibitory effect on tumor and inflammations. Synonyms: Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,7β,15α,25R)-; (3β,7β,15α,25R)-3,7,15-Trihydroxy-11,23-dioxolanost-8-en-26-oic acid; Ganoderic acid C 2; (2R,6R)-2-methyl-4-oxo-6-((3S,5R,7S,10S,13R,14R,15S,17R)-3,7,15-trihydroxy-4,4,10,13,14-pentamethyl-11-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)heptanoic acid. Grades: >98%. CAS No. 103773-62-2. Molecular formula: C30H46O7. Mole weight: 518.68.
Ganoderic Acid C2
Ganoderic Acid C2. Group: Biochemicals. Grades: Plant Grade. CAS No. 98296-48-1. Pack Sizes: 5mg. Molecular Formula: C30H46O7, Molecular Weight: 518.68. US Biological Life Sciences.
Ganoderic acid D (GAD) is one of the major components in Ganoderma triterpenes. GAD treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with an IC(50) value of 17.3 +/- 0.3 microM. Synonyms: Ganoderic Acid D; 108340-60-9; GanodericacidD; Ganodernic acid D; SCHEMBL3676373; CHEMBL2205002; HY-N1511; BDBM50021402; AKOS032946021; MS-29559; CS-0017054; (6R)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 108340-60-9. Molecular formula: C30H42O7. Mole weight: 514.6.
Ganoderic Acid D
Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 108340-60-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ganoderic acid D2
Ganoderic acid D2. Group: Biochemicals. Grades: Plant Grade. CAS No. 97653-94-6. Pack Sizes: 5mg. Molecular Formula: C30H42O8, Molecular Weight: 530.66. US Biological Life Sciences.
Worldwide
Ganoderic acid D2
Ganoderic acid D2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: 7,12-Dihydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid; 7,12-Dihydroxy-3,11,15,23-tetraoxo-(7beta,12beta)-Lanost-8-en-26-oic acid. Grades: >98%. CAS No. 97653-94-6. Molecular formula: C30H42O8. Mole weight: 530.65.
Ganoderic acid F
Ganoderic acid F, an organic natural compound, emanates from Ganoderma lucidum, a fungus. Well-recognized for its remarkable anti-inflammatory attributes, it constitutes a crucial constituent in the research of chronic inflammatory ailments encompassing arthritand asthma. Grades: >98%. CAS No. 98665-14-6. Molecular formula: C32H42O9.
Ganoderic Acid F
Ganoderic Acid F. Group: Biochemicals. Grades: Plant Grade. CAS No. 98665-15-7. Pack Sizes: 10mg. Molecular Formula: C32H42O9, Molecular Weight: 570.67. US Biological Life Sciences.
Worldwide
Ganoderic acid F, deacetyl-
Ganoderic acid F, deacetyl-. Group: Biochemicals. CAS No. 100665-44-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ganoderic acid G
Ganoderic acid G is an exquisite natural compound extracted from Ganoderma lucidum,mainly used for studying hepatic ailments, neoplastic disorders and inflammatory responses. This intriguing molecule has remarkable attributes encompassing potent antioxidative and anti-cancerous actions. Synonyms: (3beta,7beta,12beta)-3,7,12-trihydroxy-11,15,23-trioxolanost-8-en-26-oic acid. Grades: >98%. CAS No. 98665-22-6. Molecular formula: C30H44O8.
Ganoderic Acid G
Ganoderic Acid G. Group: Biochemicals. Grades: Plant Grade. CAS No. 98665-22-6. Pack Sizes: 10mg. Molecular Formula: C30H44O8, Molecular Weight: 532.67. US Biological Life Sciences.
Worldwide
Ganoderic acid I
Ganoderic acid I. Group: Biochemicals. Grades: Plant Grade. CAS No. 98665-20-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ganoderic acid I
Ganoderic acid I is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: 6-[(3S,5R,7S,10S,13R,14R,17S)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-4-oxoheptanoic acid. Grades: >98%. CAS No. 98665-20-4. Molecular formula: C30H44O8. Mole weight: 532.674.
Ganoderic acid LM2. Group: Biochemicals. Grades: Plant Grade. CAS No. 508182-41-0. Pack Sizes: 5mg. Molecular Formula: C30H42O7, Molecular Weight: 514.66. US Biological Life Sciences.
Worldwide
Ganoderic acid LM2
Ganoderic acid LM2 is a triterpenoid compound found in the fruit body of Ganoderma lucidum. Synonyms: (7beta,23S,24E)-7,23-Dihydroxy-3,11,15-trioxo-lanosta-8,24-dien-26-oic acid. Grades: >98%. CAS No. 508182-41-0. Molecular formula: C30H42O7. Mole weight: 514.65.