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| Product | Description | |
|---|---|---|
| Gaultherin | Gaultherin. Group: Biochemicals. Alternative Names: Monotropitoside; Monotropitin. Grades: Plant Grade. CAS No. 490-67-5. Pack Sizes: 10mg. Molecular Formula: C19H26O12, Molecular Weight: 446.403. US Biological Life Sciences. |  Worldwide |
| Gavestinel | Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV 150526. CAS No. 153436-22-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-150138. |  |
| Gavestinel | Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), displaying >1000-fold selectivity over NMDA, AMPA, and kainate binding sites. Gavestinel exhibits a neuroprotective property in animal models of ischaemic stroke. Uses: Glycine agents. Synonyms: 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[3-oxo-3-(phenylamino)-1-propenyl]-, (E)-; 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-1H-indole-2-carboxylic acid; GV 150526; GV 150526X; (E)-4,6-dichloro-3-(3-oxo-3-(phenylamino)prop-1-en-1-yl)-1H-indole-2-carboxylic acid. Grades: ≥95%. CAS No. 153436-22-7. Molecular formula: C18H12Cl2N2O3. Mole weight: 375.21. |  |
| Gaxilose | Gaxilose is a synthetic disaccharide and a substrate of intestinal lactase. It can be applicated in a new noninvasive diagnostic test based on urine or serum measurement of D-xylose after lactase cleavage of orally administered gaxilose. Uses: Used in a new noninvasive diagnostic test based on urine or serum measurement of d-xylose after lactase cleavage of orally administered 4-galactosylxylose. Synonyms: 4-O-Galactosyl-D-xylose; 4-O-Galactosylxylose; 4-Galactosylxylose; Gaxilose;(3R,4R,5R)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol. Grades: 98%. CAS No. 14087-31-1. Molecular formula: C11H20O10. Mole weight: 312.27. | |
| GB1-Cyanine 3 | GB1-Cyanine 3. Group: Biochemicals. Alternative Names: 2-[3-[1-[17-(a-D-Glucopyranosyloxy)-5-oxo-9,12-dioxa-6,15-diazaheptadec-1-yl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-3H-indolium; GB1-Cy3. Grades: Highly Purified. CAS No. 1065004-53-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C43H63N4O9. US Biological Life Sciences. | Worldwide |
| Gb3-beta-mp | Gb3-beta-mp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Methoxyphenyl O-(alpha-D-Galactopyranosyl)-(1-4)-O-(beta-D-galactopyranosyl)-(1-4)-beta-D-glucopyranoside. Product Category: Heterocyclic Organic Compound. CAS No. 898826-64-7. Molecular formula: C25H38O17. Mole weight: 610.56. Purity: 0.96. IUPACName: (2R,3S,4S,5R,6S)-2-[(2S,3R,4R,5S,6S)-6-[(2S,3S,4R,5S,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(4-methoxyphenoxy)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol. Density: 1.663g/cm³. Product ID: ACM898826647. Alfa Chemistry ISO 9001:2015 Certified. |  |
| GB 83 | GB 83 is a selective antagonist of human protease activated receptor 2 (PAR2) (IC50 = 2 mM). Synonyms: GB83; GB 83; GB-83; N-((S)-3-Cyclohexyl-1-((2S,3S)-1-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)-3-methyl-1-oxopentan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide. Grades: 99%. CAS No. 1252806-86-2. Molecular formula: C32H44N4O4. Mole weight: 548.72. | |
| G(Boc) Acetic acid | A nucleobase for PNA synthesis. Grades: 98%. CAS No. 1028077-12-4. Molecular formula: C12H15N5O5. Mole weight: 309.28. | |
| Gboxin | Gboxin is an oxidative phosphorylation inhibitor in cancer cells, which inhibits the activity of F0F1 ATP synthase. Synonyms: 2-ethyl-1-methyl-3-[2-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-1H-benzimidazolium, monochloride. Grades: ≥98%. CAS No. 2101315-36-8. Molecular formula: C22H33N2O2·Cl. Mole weight: 392.96. | |
| Gboxin chloride | Gboxin chloride is an oxidative phosphorylation inhibitor that targets glioblastoma but not embryonic fibroblasts or neonatal astrocytes. Gboxin rapidly and irreversibly compromises oxygen consumption in glioblastoma cells. Gboxin relies on its positive charge to associate with mitochondrial oxidative phosphorylation complexes in a manner that is dependent on the proton gradient of the inner mitochondrial membrane, and it inhibits the activity of F0F1 ATP synthase. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2101315-36-8. Molecular formula: C22H33ClN2O2. Mole weight: 392.97. Purity: >98%. IUPACName: 2-Ethyl-1-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-3-methyl-1H-benzo[d]imidazol-3-ium chloride. Canonical SMILES: C[N+]1=C(CC)N(CC(O[C@H]2[C@H](C(C)C)CC[C@@H](C)C2)=O)C3=CC=CC=C31.[Cl-]. Product ID: ACM2101315368. Alfa Chemistry ISO 9001:2015 Certified. | |
| GBR 12783 dihydrochloride | GBR 12783 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-75-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GBR 12783 dihydrochloride | GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [ 3 H]dopamine uptake by rat and mice striatal synaptosomes with IC 50 s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67469-75-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100968. | |
| GBR 12783 dihydrochloride | GBR 12783 dihydrochloride is a potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM). Synonyms: GBR 12783 dihydrochloride; GBR12783 dihydrochloride; GBR-12783 dihydrochloride; 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 67469-75-4. Molecular formula: C28H32N2O.2HCl. Mole weight: 485.5. | |
| GBR 12909 dihydrochloride | solid, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| GBR 12909 Dihydrochloride | A potent inhibitor of dopamine active transporter (DAT, Ki=1nM, IC50=40 and 51nM) with >100 fold selectivity over noradrenalin and 5-HT re-uptake transporter. Shown to produce behavioral profile in mice for bipolar mania disease model and ADHD disease models. Group: Biochemicals. Alternative Names: 1-[2-[Bis (4-fluorophenyl) methoxy]ethyl]-4- (3-phenylpropyl) -piperazine Dihydrochloride (9CI); GBR 12909; I 893; Vanoxerine Dihydrochloride; 1-[2-[Bis (4-fluorophenyl) methoxy]ethyl]-4- (3-phenylpropyl) -piperazine Hydrochloride (1:2). Grades: Highly Purified. CAS No. 67469-78-7. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??F?N?O 2HCl, Molecular Weight: 450.56 (anhydrous). US Biological Life Sciences. | Worldwide |
| GBR-12935 | GBR 12935 is a piperazine derivative and a potent and selective inhibitor of dopamine uptake with IC50 value of 3.7nM. It is found to have multiple binding sites in rat and human brains. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. It(1-9 nM) dose-dependently inhibited active uptake of [3H]dopamine in homogenates of the nucleus accumbens and could inhibit DA uptake with IC50 value of 3.7nM in vitro. It elevated locomotion to a greater extent in C57BL/6J mice at the maximally active dose of 10 mg/kg in vivo. It shows a Kd value of 1.08nM in dopamine transporter transfected COS-7 cells. It is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. Uses: Gbr 12935 inhibits da uptake with ic50 value of 3.7nm in vitro. it elevated locomotion to a greater extent in c57bl/6j mice at the maximally active dose of 10 mg/kg in vivo. it shows a kd value of 1.08nm in dopamine transporter transfected cos-7 cells. Synonyms: GBR-12935; GBR 12935; GBR12935; 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine; 1-Hydrocinnamyl-4-[2-(diphenylmethoxy)ethyl]piperazine; Piperazine, 1-(2-(diphenylmethoxy)ethyl)-4-(3-phenylpropyl)-;N-[3-tert-Butyl-1-(4-Methylphenyl)-1H-pyrazol-5-yl]-N-[4-[2-(4-Morpholinyl)ethoxy]naphthalen-1-yl]urea;1-(2-(Benzhydryloxy)ethyl)-4-(3-phenylpropyl)piperazine. Grades: 98%. CAS No. 76778-22-8. Molecular formula: C28H34N2O. Mole weight: 414.58. | |
| GBR-12935 | GBR-12935. Group: Polymers. CAS No. 9060-5-3. |  |
| GBR 12935 dihydrochloride | GBR 12935 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-81-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GBR-12935 dihydrochloride | GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor. Synonyms: GBR12935 dihydrochloride; GBR-12935 dihydrochloride. Grades: 0.99. CAS No. 67469-81-2. Molecular formula: C28H36Cl2N2O. Mole weight: 487.509. | |
| GBR-12935 HCl | GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GBR-12935; GBR 12935; GBR12935. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 67469-81-2. Molecular formula: C28H36Cl2N2O. Mole weight: 487.51. Purity: >98%. IUPACName: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride. Canonical SMILES: [H]Cl.[H]Cl.N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(CCCC4=CC=CC=C4)CC1. Product ID: ACM67469812. Alfa Chemistry ISO 9001:2015 Certified. Categories: GBR 12935 dihydrochloride. | |
| GBR 13069 dihydrochloride | GBR 13069 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GBR 13069 dihydrochloride | GBR 13069 dihydrochloride is a potent and selecticve inhibitor of dopamine uptake (IC50 = 40 nM). Synonyms: GBR 13069 dihydrochloride; GBR13069 dihydrochloride; GBR-13069 dihydrochloride; (1-(2-(Bis-(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine dihydrochloride. CAS No. 67469-45-8. Molecular formula: C28H30F2N2O.2HCl. Mole weight: 521.48. | |
| GBT-440 | GBT-440 is a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders. Uses: Hematologic agents. Synonyms: Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011; 2-hydroxy-6-[[2-(2-propan-2-ylpyrazol-3-yl)pyridin-3-yl]methoxy]benzaldehyde; Hemoglobin Modulators-1. Grades: >98%. CAS No. 1446321-46-5. Molecular formula: C19H19N3O3. Mole weight: 337.37. | |
| GC 1 | GC 1. Group: Biochemicals. Grades: Purified. CAS No. 211110-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GC376 | GC376 Inhibitor. Uses: Scientific use. Product Category: T5188. CAS No. 1416992-39-6. |  |
| GC376 sodium | GC376 is a 3CLpro inhibitor which is previously reported to be active against the 3CLpro of multiple coronaviruses, including SARS-CoV, but with highest potency against FIPV in cell culture. GC376 inhibits the replication of viruses TGEV, FIPV and PTV with IC50 values of 0.15, 0.2 and 0.15 μM. Synonyms: GC376 sodium; GC 376 sodium; GC-376 sodium; (2S) -1-hydroxy-2-[[ (2S) -4-methyl-2- (phenylmethoxycarbonylamino) pentanoyl]amino]-3- (2-oxopyrrolidin-3-yl) propane-1-sulfonate sodium. Grades: ≥98% (HPLC). CAS No. 1416992-39-6. Molecular formula: C21H30N3NaO8S. Mole weight: 507.53. | |
| GC376 sodium | GC376 sodium is a 3CLpro inhibitor; inhibits the replication of viruses TGEV, FIPV and PTV with IC 50 values of 0.15, 0.2 and 0.15 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416992-39-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-100721. | |
| GC7 Sulfate | GC7 Sulfate is a deoxyhypusine synthase ( DHPS ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 150417-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108314A. | |
| GCase modulator-1 | GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC 50 =2.23 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 796079-91-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156287. | |
| GCB Graphitized Carbon Black | Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSol | |
| G(Cbz)-acetic acid | Cas No. 169287-69-8. Molecular formula: C15H13N5O5. Mole weight: 343.29. | |
| GC Enhancer | GC Enhancer. Gc enhancer should be used with dna ploymerase to optimize pcr from complex templates including gc rich. the storage concentration is 10×. the working concentration can adjust between 0.5×-5×. Group: Cloning Enzymes. Purity: 200ul. Storage: Store at -20 ?. Cat No: CE-3007. |  |
| Gc-globulin from human plasma | ?90% (SDS-PAGE), lyophilized powder (containing sodium chloride and sodium phosphate buffer salt). Group: Fluorescence/luminescence spectroscopy. | |
| GCK, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| GcLEAP-2 | GcLEAP-2 is isolated from tenopharyngodon idella [Grass carp] and has antimicrobial activity. | |
| GCN5 (727-837) human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| g-Cyclodextrin | g-Cyclodextrin. CAS No. 17465-86-0. Product ID: 4-00295. Purity: 20 mM solution. |  |
| g-Cyclodextrin | . Grades: pyrogen free. CAS No. 17465-86-0. Product ID: 8-01027. Molecular formula: [C6H10O5]8. Mole weight: 1297.15. | |
| g-Cyclodextrin | g-Cyclodextrin. Grades: pharmaceutical grade. CAS No. 17465-86-0. Product ID: 8-01134. Molecular formula: [C6H10O5]8. Mole weight: 1297.15. | |
| g-Cyclodextrin acetate | g-Cyclodextrin acetate. Product ID: 4-00311. Purity: DS 14-16. | |
| g-Cyclodextrin acetate | g-Cyclodextrin acetate. Product ID: 4-00310. Purity: DS ~8. Properties: sparingly water soluble. | |
| g-Cyclodextrin D-alpha-Tocopherol complex | dietary fiber supplement. Product ID: 4-00691. Purity: Tocopherol ~12%. | |
| g-Cyclodextrin hydrate | also available in pharma grade. CAS No. 17465-86-0. Product ID: 4-00025. Molecular formula: [C6H10O5]8. Mole weight: 1297.15. Properties: ash <1% pH 4.00-7.00 moisture <5%. | |
| g-Cyclodextrin Hydrate | g-Cyclodextrin Hydrate. CAS No. 91464-90-3. Product ID: 4-00403. Molecular formula: C48H82O41. Mole weight: 1315.14. | |
| g-Cyclodextrin phosphate sodium salt | g-Cyclodextrin phosphate sodium salt. CAS No. 199684-62-3. Product ID: 4-00189. | |
| g-Cyclodextrin phosphate sodium salt | g-Cyclodextrin phosphate sodium salt. CAS No. 199684-62-3. Product ID: 4-00188. Molecular formula: | |
| g-Cyclodextrin polymer | g-Cyclodextrin polymer. Product ID: 4-00237. Properties: insoluble swelling resin beads. | |
| g-Cyclodextrin standard | g-Cyclodextrin standard. CAS No. 17465-86-0. Product ID: 4-00282. | |
| g-Cyclodextrin succinate | g-Cyclodextrin succinate. Product ID: 4-00575. Molecular formula: C60H95O49. Mole weight: 1600.38. Properties: powder, granule size <0.2 mm. Source : from crab shells. | |
| g-Cyclodextrin sulfate | g-Cyclodextrin sulfate. CAS No. 126881-41-2. Product ID: 4-00197. Molecular formula: C48H80-nO30+3nSnNan. | |
| g-Cyclodextrin sulfate | g-Cyclodextrin sulfate. CAS No. 126881-41-2. Product ID: 4-00107. Molecular formula: C48H80-nO30+3nSnNan. Properties: DS ~2.0. | |
| g-Cyclodextrin sulfate | g-Cyclodextrin sulfate. CAS No. 126881-41-2. Product ID: 4-00106. Molecular formula: C48H80-nO30+3nSnNan. Properties: DS ~2.0. | |
| g-Cyclodextrin sulfate polymer | g-Cyclodextrin sulfate polymer. Product ID: 4-00244. Properties: DS ~4. | |
| g-Cyclodextrin sulfate standard | g-Cyclodextrin sulfate standard. Product ID: 4-00285. | |
| GD1a-Oligosaccharide | GD1a-Oligosaccharide is an esteemed compound, demonstrating remarkable potential in studying peripheral neuropathies as well as neurodegenerative disorders. Functioning as an astute modulator of ganglioside metabolism, it exerts an exquisite influence on nerve cell viability while stimulating the process of neuronal regeneration. Synonyms: GD1aSaccharide. CAS No. 1627679-86-0. Molecular formula: C48H79N3O37. Mole weight: 1290.14. | |
| GD1b-Ganglioside | GD1b-Ganglioside is a pivotal biomolecule, finding widespread application for the comprehensive investigation and comprehension of diverse neurodegenerative ailments, including Parkinson's disease is alzheimer's disease and Multiple Sclerosis. Synonyms: GD1b-Ganglioside. CAS No. 19553-76-5. Molecular formula: C80H144N4O37. Mole weight: 1754. | |
| GD1b-Oligosaccharide | GD1b-Oligosaccharide is a crucial component widely used in the research of neurological diseases, including Alzheimer's and Parkinson's. With its bioactive properties, GD1b-Oligosaccharide holds promise for targeted drug delivery systems, disease diagnostics and advanced research in neurobiology. Synonyms: Galb1-3GalNAcb1-4(Neu5Aca2-8Neu5Aca2-3)Galb1-4Glc. Molecular formula: C48H77N3O37Na2. Mole weight: 1334.10. | |
| GD2-Ganglioside | GD2-Ganglioside is a complex lipid molecule extensively present within the neuroblastoma tumours cells. This molecule is the focal point of numerous immunotherapies such as chimeric antigen receptor (CAR) T-cell therapy and monoclonal antibodies and has the ability to specifically recognize and demolish GD2-Ganglioside expressing cancer cells. Synonyms: GD2-Ganglioside; Disialoganglioside-GD2. CAS No. 65988-71-8. Molecular formula: C74H134N4O32. Mole weight: 1591.9. | |
| GD2-GANGLIOSIDE | GD2-GANGLIOSIDE. Uses: Designed for use in research and industrial production. Appearance: Film (dried in situ). CAS No. 65988-71-8. Molecular formula: C74H134N4O32. Mole weight: 1591.86. Purity: 0.95. Product ID: ACM65988718. Alfa Chemistry ISO 9001:2015 Certified. Categories: GM2 (ganglioside). | |
| GD2-Oligosaccharide | GD2-Oligosaccharide is a biomedical product used in the research of neuroblastoma. It has been found to target the GD2 antigen present on neuroblastoma cells. Molecular formula: C42H67N3O32Na2. Mole weight: 1171.96. | |
| GD2-Oligosaccharide-b-(N-acetyl-propargyl) | GD2-Oligosaccharide-b-(N-acetyl-propargyl) is a remarkable biomedical compound, emerging as a formidable compound in the research of neuroblastoma, an affliction predominantly encountered during early stages of life. Synonyms: GD2-Saccharide-b-NAc-propargyl. Molecular formula: C47H72N4O32Na2. Mole weight: 1251.06. | |
| GD2-Oligosaccharide-desthiobiotin | GD2-Oligosaccharide-desthiobiotin is a compound product used in the research of GD2-positive cancers, composed of desthiobiotin and GD2 oligosaccharide. It specifically targets GD2 receptors on cancer cells. Molecular formula: C65H106N10O37 2Na. Mole weight: 1665.56. | |
| GD2-Oligosaccharide-sp-biotin | GD2-Oligosaccharide-sp-biotin is a powerful tool used for researching various diseases such as neuroblastoma, melanoma and certain other cancers. It specifically targets GD2 oligosaccharide. The addition of biotin enables efficient detection and purification of GD2 oligosaccharide in experimental settings. Molecular formula: C65H104N10O37SNa2. Mole weight: 1695.61. | |
| GD3-Ganglioside | GD3-Ganglioside, a glycosphingolipid, is an intricate modulator of cell growth, differentiation and apoptosis. Anti-cancer therapies utilizing GD3-Ganglioside as a therapeutic target have shown significant promise, making it a distinguished focus of research in the realm of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. In addition to the fascinating roles delineated above, GD3-Ganglioside has been extensively studied for its potential as an antiviral agent owing to its involvement in the immune response. Synonyms: disialoganglioside GD3; 62010-37-1; Ganglioside GD3 Sodium Salt; Ganglioside GD3 disodium salt; PD077037. CAS No. 62010-37-1. Molecular formula: C70H123N3Na2O29. Mole weight: 1516.7. | |
| GD3-Ganglioside, biotin labelled | | |
| GDC-0068 dihydrochloride | Testing against a broad panel of 230 kinases, GDC-0068 only inhibits 3 kinases by >70% at 1 μM concentration (PRKG1α, PRKG1β, and p70S6K, with IC50 of 98 nM, 69 nM, and 860 nM, respectively). GDC-0068 displays >100-fold selectivity for Akt over PKA with IC50 of 3.1 μM. In LNCaP, PC3 and BT474M1 cells, GDC-0068 treatment inhibits the phosphorylation of the Akt substrate, PRAS40 with IC50 of 157 nM, 197 nM, and 208 nM, respectively. Furthermore, GDC-0068 selectively inhibits cell cycle progression and viability of cancer cell lines driven by Akt signaling, including those with defects in the tumor suppressor PTEN, oncogenic mutations in PIK3CA, and amplification of HER2, with strongest effects in HER2+ and Luminal subtypes. Oral administration of GDC-0068 in PC3 prostate tumor xenografts model induces down-regulation of p-PRAS40. In BT474-Tr xenografts, GDC-0068 treatment reduces pS6 and peIF4G levels, re-localizes FOXO3a to nucleus, and induces feedback upregulation of HER3 and pERK. Administration of GDC-0068 exhibits potent antitumor efficacy in multiple xenograft tumor models, including the PTEN-deficient prostate cancer models LNCaP and PC3, the PIK3CA H1047R mutant breast cancer model KPL-4, and MCF7-neo/HER2 tumor model. Synonyms: Ipatasertib dihydrochloride; RG-7440 dihydrochloride; GDC-0068 dihydrochloride; RG 7440 dihydrochloride; GDC 0068 dihydrochloride; RG7440 dihydrochloride; GDC0068 dihydrochloride. Grades: >98%. CAS No. 1396257-94-5. Molecular formula: C24H34Cl3N5O2. Mole weight: 530.92. | |
| GDC-0077 | Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and results in the inhibition of growth and survival of PI3K-overexpressing tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GDC-0077; GDC 0077; GDC0077; Inavolisib; RG6114; RG 6114; RG-6114. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2060571-02-8. Molecular formula: C18H19F2N5O4. Mole weight: 407.38. Purity: >98%. IUPACName: (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide. Canonical SMILES: C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1. Product ID: ACM2060571028. Alfa Chemistry ISO 9001:2015 Certified. | |
| GDC-0077 | GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Synonyms: GDC-0077; GDC 0077; GDC0077. (2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide. CAS No. 2060571-02-8. Molecular formula: C18H19F2N5O4. Mole weight: 407.37. | |
| GDC-0084 | GDC-0084, a PI3K inhibitor, has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. It was just licensed to Novogen and start a Phase II trial for Glioma. Uses: Gdc-0084 is a pi3k inhibitor that has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. Synonyms: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084; 5-(6,6-dimethyl-4-morpholin-4-yl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl)pyrimidin-2-amine. Grades: 98%. CAS No. 1382979-44-3. Molecular formula: C18H22N8O2. Mole weight: 382.19. | |
| GDC-0152 | GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic GDC-0152 binds to the Smac binding groove on IAPs, including the direct caspase inhibitor X chromosome-linked IAP (XIAP) and the cellular IAPs 1 and 2, which may inhibit their activities and promote the induction of apoptosis through apoptotic signaling pathways. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding to and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains. Smac, the endogenous IAP antagonist, relies on its N-terminal four amino-acid motif for binding to IAPs. Synonyms: GDC-0152; GDC0152; GDC 0152. CAS No. 873652-48-3. Molecular formula: C25H34N6O3S. Mole weight: 498.646. | |
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