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Gemcitabine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: gemcitabine, dFdC, Gamcitabine, Gemcitabina, Gemcitabinum, Gemzar, DFdCyd, Gemcitabine stereoisomer, nchembio.90-comp2, DDFC, Gemzar (hydrochloride), 2,2-Difluorodeoxycytidine, Gemcitabine (USAN/INN), Gemcitabinum [INN-Latin], UNII-B76N6SBZ8R, Gemcitabina [INN-Spanish], Inno-D07001, 2,2-DiF-dC, CCRIS 8984, NChemBio.2007.10-comp25. Product Category: Heterocyclic Organic Compound. CAS No. 103882-84-4. Molecular formula: C9H11F2N3O4. Mole weight: 263.198146 [g/mol]. Purity: 0.96. IUPACName: 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Canonical SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F. ECNumber: 619-100-6. Product ID: ACM103882844. Alfa Chemistry ISO 9001:2015 Certified.
Gemcitabine-13C,15N2 hydrochloride
Gemcitabine- 13 C, 15 N 2 (hydrochloride) is the 13 C and 15 N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: LY 188011- 13 C, 15 N2 hydrochloride. CAS No. 2757566-59-7. Pack Sizes: 500 μg. Product ID: HY-B0003S.
Labeled Gemcitabine, an antineoplastic. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine-13C,15N2 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine-5'-diphosphate
A diphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as an inhibitor of ribonucleotide reductases (RNRs). Synonyms: 2'-deoxy-2',2'-difluorocytidine 5'-(trihydrogen diphosphate). Grades: ≥ 95 % by HPLC. CAS No. 116371-66-5. Molecular formula: C9H13F2N3O10P2. Mole weight: 423.16.
Gemcitabine 5'-elaidate
Gemcitabine 5'-elaidate. Group: Biochemicals. Alternative Names: (E)-((2R,3R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate; 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-9-octadecenoate; CP-4126; LVT derivative of Gemcitabine; CO-101. Grades: Highly Purified. CAS No. 210829-30-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H43F2N3O5. US Biological Life Sciences.
Worldwide
Gemcitabine-5'-triphosphate
A triphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-Difluorocytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C9H14N3O13P3F2. Mole weight: 503.14.
Gemcitabine (alpha-Isomer) Hydrochloride
Gemcitabine (alpha-Isomer) Hydrochloride is an α-Anomer of Gemcitabine. Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Synonyms: 1'-Epi Gemcitabine Hydrochloride; 4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride. Grades: > 95%. CAS No. 122111-05-1. Molecular formula: C9H12F2N3O4Cl. Mole weight: 299.65.
Gemcitabine Diphosphate Ammonium Salt
Gemcitabine Diphosphate is a phosphorylated metabolite of Gemcitabine, an antineoplastic agent. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine 5-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5-Diphosphate Triethylamine Salt. Grades: Highly Purified. CAS No. free acid: 116371-66-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Diphosphate Choline
Gemcitabine derivative. An antineoplastic agent. Synonyms: Gemcitabine 5'-Diphosphate Choline. Grades: 95%. CAS No. 1643126-46-8. Molecular formula: C14H24F2N4O10P2. Mole weight: 508.31.
Gemcitabine Diphosphate Choline
Gemcitabine derivative. An antineoplastic agent. Group: Biochemicals. Alternative Names: Gemcitabine 5-Diphosphate Choline. Grades: Highly Purified. CAS No. 1643126-46-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Diphosphate Triethylamine Salt (>90%)
Gemcitabine Diphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5'-Diphosphate Triethylamine Salt. Grades: 90%. Molecular formula: C27H58F2N6O10P2. Mole weight: 726.73.
Gemcitabine elaidate
Gemcitabine elaidate (CP-4126) is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate exhibits anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-4126; CO-101; Gemcitabine 5'-elaidate. CAS No. 210829-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13538.
Gemcitabine elaidate
Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Synonyms: CO-101; CO101; CO 101; CP-4126; CP4126; CP 4126. CAS No. 210829-30-4. Molecular formula: C27H43F2N3O5. Mole weight: 527.654.
Gemcitabine elaidate hydrochloride
Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate hydrochloride exhibits anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-4126 hydrochloride; CO-101 hydrochloride; Gemcitabine 5'-elaidate hydrochloride. CAS No. 2918768-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13538A.
Gemcitabine EP Impurity B
Gemcitabine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122111-05-1. Molecular Formula: C9H11F2N3O4·ClH. Mole Weight: 299.66. Catalog: APB122111051.
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H11F2N3O4 · HCl. CAS No. 122111-03-9. Prepack ID 56199790-5g. Molecular Weight 299.66. See USA prepack pricing.
Gemcitabine hydrochloride
Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Uses: Antimetabolites, antineoplastic. Synonyms: Gemzar; Gemcitabine HCl; LY188011 hydrochloride. Grades: >98%. CAS No. 122111-03-9. Molecular formula: C9H11F2N3O4.HCI. Mole weight: 299.66.
Gemcitabine hydrochloride
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagy and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 188011 hydrochloride. CAS No. 122111-03-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0003.
Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP inhibits DNA polymerase by competing with deoxycytidine triphosphate (dCTP). dFdCDP inhibits ribonucleoside reductase and DNA synthesis by causing depletion of deoxyribonucleotide pools, and thus potentiating the effects of dFdCTP. Gemcitabine can be inactivated to 2,2'-difluorodeoxyuridine, mainly by deoxycytidine deaminase. Also, 5'-nucleotidase catalyses the conversion of nucleotides to nucleosides and inhibits nucleoside kinases. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd. Grades: Highly Purified. CAS No. 122111-03-9. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Gemcitabine hydrochloride EP impurity A/Lamivudine EP impurity E
Gemcitabine hydrochloride EP impurity A/Lamivudine EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71-30-7. Molecular Formula: C4H5N3O. Mole Weight: 111.1. Catalog: APB71307.
Gemcitabine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122111-12-0. Molecular Formula: C5H6F2O4. Mole Weight: 168.1. Catalog: APB122111120.
Gemcitabine Impurity 5
Gemcitabine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((2R,3R,5S)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate. CAS No. 134877-43-3. Molecular Formula: C20H18F2O8S. Mole Weight: 456.41. Catalog: APB134877433.
Gemcitabine Impurity 6
Gemcitabine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122111-02-8. Molecular Formula: C19H14F2O6. Mole Weight: 376.31. Catalog: APB122111028.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122111-07-3. Molecular Formula: C12H10F2O5. Mole Weight: 272.2. Catalog: APB122111073.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-39-9. Molecular Formula: C23H19F2N3O6. Mole Weight: 471.41. Catalog: APB134790399.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-40-2. Molecular Formula: C23H19F2N3O6. Mole Weight: 471.41. Catalog: APB134790402.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143234-91-7. Molecular Formula: C14H16F2O6. Mole Weight: 318.27. Catalog: APB143234917.
Gemcitabine Impurity 9
Gemcitabine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 866473-31-6. Molecular Formula: C19H16F2O7. Mole Weight: 394.33. Catalog: APB866473316.
Gemcitabine Impurity C (EP)
Gemcitabine Impurity C is a metabolite of Gemcitabine in human plasma. Synonyms: 2',2'-Difluoro-2'-deoxyuridine; 2'-Deoxy-2',2'-difluorouridine; 2',2'-Difluorodeoxyuridine; 1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)pyrimidin-2,4(1H,3H)-dione. Grades: ≥97% by HPLC. CAS No. 114248-23-6. Molecular formula: C9H10F2N2O5. Mole weight: 264.19.
Gemcitabine Monophosphate
A monophosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-difluorodeoxycytidine Monophosphate; Gemcitabine 5'-phosphate. Grades: ≥ 95 % by HPLC. CAS No. 116371-67-6. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine Monophosphate-13C,15N2 Formate Salt
Gemcitabine Monophosphate-13C,15N2 Formate Salt. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid-13C,15N2 Formate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C913CH14F2N15N2O9P, Molecular Weight: 392.18. US Biological Life Sciences.
Worldwide
Gemcitabine monophosphate disodium salt
Gemcitabine monophosphate disodium salt is a derivative of gemcitabine. Gemcitabine, under the trade name Gemzar, is a chemotherapy drug for the treatment of various cancers. Gemcitabine is used as a first-line medication for pancreatic cancer. Synonyms: Gemcitabine monophosphate disodium salt monohydrate; Gemcitabine monophosphate disodium; GemMP. CAS No. 1638288-31-9. Molecular formula: C9H12F2N3Na2O8P. Mole weight: 405.158.
Gemcitabine Monophosphate, Formate salt
Gemcitabine derivative. An antineoplastic agent. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluoro-5'-cytidylic acid formate. Grades: Highly Purified. CAS No. 116371-67-6. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Gemcitabine (Standard)
Gemcitabine (Standard) is the analytical standard of Gemcitabine. This product is intended for research and analytical applications. Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagy and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 95058-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17026R.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a phosphorylated metabolite of Gemcitabine , an antineoplastic agent. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine). Grades: 97%. Molecular formula: C21H44F2N5O13P2. Mole weight: 705.52.
Gemcitabine Triphosphate (triethylammonium salt form)
An impurity of Gemcitabine. Gemcitabine is an antineoplastic chemotherapy medication of the antimetabolites class. It halts cell division through damaging RNA or DNA which control the process. It can be used to treat multiple cancers. Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) triethylammonium. Grades: 95%. CAS No. 1035495-84-1. Molecular formula: C33H74F2N7O13P3. Mole weight: 907.9.
Gemfibrozil is an activator of PPAR-α , used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with K i values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-719. CAS No. 25812-30-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0258.
Gemfibrozil
Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid. Other brand names include Jezil and Gen-Fibro. Synonyms: CI-719; CI 719;CI719. Grades: >98%. CAS No. 25812-30-0. Molecular formula: C15H22O3. Mole weight: 250.33.
Gemfibrozil
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H22O3. CAS No. 25812-30-0. Prepack ID 48653561-5g. Molecular Weight 250.33. See USA prepack pricing.
Gemfibrozil 1-O-b-Glucuronide
The major metabolite of Gemfibrozil. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] β-D-Glucopyranuroic Acid; Gemfibrozil Glucuronide. Grades: Highly Purified. CAS No. 91683-38-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C21H30O9, Molecular Weight: 426.46. US Biological Life Sciences.
The major labeled metabolite of Gemfibrozil. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-Glucopyranuroic Acid-d6;Gemfibrozil Glucuronide. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
A serum lipid regulating agent used as an antihyperlipoproteinem ic. Group: Biochemicals. Alternative Names: 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Gemfibrozil Acyl-beta-D-Glucuronide
Gemfibrozil Acyl-beta-D-Glucuronide is the major metabolite of Gemfibrozil. It can be oxidized to a benzyl radical intermediate which binds to the γ-meso position of heme. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2-dimethylpentanoate] b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 91683-38-4. Molecular formula: C21H30O9. Mole weight: 426.47.
Gemfibrozil b-D-glucuronide-D6
Gemfibrozil b-D-glucuronide-D6 is a remarkable compound of immense significance, finding its purpose in the therapeutic research of cardiovascular disorders. Specifically tailored to study the levels of cholesterol and triglycerides, this compound manifests its influence as a distinguished PPAR-alpha agonist. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-glucopyranuronic acid. Molecular formula: C21H24D6O9. Mole weight: 432.49.
Gemfibrozil-d6 1-O- β-D-Glucuronide Benzyl Ester
A labelled Gemfibrozil (G305750) glucuronide derivative. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Di(methyl-d3)phenoxy)-2,2-dimethylpentanoate] β-D-Glucopyranuroic Acid Benzyl Ester; Gemfibrozil-d6 Glucuronide Benzyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An isotopically labeled analog of a serum lipid regulating agent used as an antihyperlipoproteinem ic. Group: Biochemicals. Alternative Names: 5-(2,5-Dimethylphenoxy)-2,2-dimethyl-(d6)-pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemfibrozil EP impurity D
Gemfibrozil EP impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1798429-95-4. Molecular Formula: C18H26O3. Mole Weight: 290.4. Catalog: APB1798429954.
Gemfibrozil EP impurity E
Gemfibrozil EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 500904-61-0. Molecular Formula: C18H26O3. Mole Weight: 290.4. Catalog: APB500904610.
Gemfibrozil EP impurity F
Gemfibrozil EP impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 500904-64-3. Molecular Formula: C18H22O. Mole Weight: 254.37. Catalog: APB500904643.
Gemfibrozil EP impurity G
Gemfibrozil EP impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3727-20-6. Molecular Formula: C11H14O. Mole Weight: 162.23. Catalog: APB3727206.
Gemfibrozil EP impurity H
Gemfibrozil EP impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 415724-02-6. Molecular Formula: C19H24O2. Mole Weight: 284.4. Catalog: APB415724026.
Gemfibrozil EP impurity I
Gemfibrozil EP impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149105-25-9. Molecular Formula: C16H24O3. Mole Weight: 264.37. Catalog: APB149105259.
Gemfibrozil impurity 1
Gemfibrozil impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 63258-18-4. Molecular Formula: C17H26O3. Mole Weight: 278.39. Catalog: APB63258184.