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| Product | Description | |
|---|---|---|
| Gefitinib, Free Base (Iressa) | EGFR tyrosine kinase inhibitor that binds to the ATP-binding site of the enzyme. The functions of the EGFR tyrosine kinase in activating the Ras signal transduction cascade and malignant cell growth are thus inhibited. It has been shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating anti-apoptotic pathways in gefitinib-sensitive non-small cell lung cancers. These mutations tend to increase sensitivity to tyrosine kinase inhibitors including gefitinib and erlotinib. The adenocarcinoma subset of non-small cell lung cancer histologies often have these mutations, which are commonly found in Asians, women, and non-smokers. Group: Biochemicals. Grades: Highly Purified. CAS No. 184475-35-2. Pack Sizes: 1g. US Biological Life Sciences. |  Worldwide |
| Gefitinib hydrochloride | Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD-1839 hydrochloride. CAS No. 184475-55-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895A. |  |
| Gefitinib hydrochloride | Gefitinib Hcl(ZD-1839 Hcl) is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Synonyms: Iressa hydrochloride; ZD 1839 hydrochloride; ZD-1839 hydrochloride; ZD1839 hydrochloride. Grades: >98%. CAS No. 184475-55-6. Molecular formula: C22H25Cl2FN4O3. Mole weight: 483.36. |  |
| Gefitinib Hydrochloride | Gefitinib Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 184475-55-6. Molecular Formula: C22H25Cl2FN4O3. Mole Weight: 483.37. Catalog: APB184475556. |  |
| Gefitinib Hydrolysate Precursor (HCl) | Gefitinib Hydrolysate Precursor (HCl). Uses: For analytical and research use. Group: Impurity standards. CAS No. 184475-70-5. Molecular Formula: C17H14Cl2FN3O3. Mole Weight: 398.22. Catalog: APB184475705. | |
| Gefitinib Impurity | Cas No. 13794-72-4. | |
| Gefitinib impurity 1 | Gefitinib impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-chloro-7-methoxyquinazolin-6-ol. CAS No. 574745-95-4. Molecular Formula: C9H7ClN2O2. Mole Weight: 210.62. Catalog: APB574745954. | |
| Gefitinib Impurity 1 | Synonyms: 2-Amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)-benzamide. Grades: > 95%. CAS No. 246512-44-7. Molecular formula: C15H23N3O4. Mole weight: 309.37. | |
| Gefitinib Impurity 1 | Gefitinib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1561173-24-7. Molecular Formula: C15H22ClN3O3. Mole Weight: 327.81. Catalog: APB1561173247. | |
| Gefitinib Impurity 10 | Gefitinib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 690206-97-4. Molecular Formula: C16H13ClFN3O2. Mole Weight: 333.75. Catalog: APB690206974. | |
| Gefitinib Impurity 11 | Gefitinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16064-25-8. Molecular Formula: C8H6N2O2. Mole Weight: 162.15. Catalog: APB16064258. | |
| Gefitinib Impurity 12 | Gefitinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 385784-71-4. Molecular Formula: C15H19N3O5. Mole Weight: 321.33. Catalog: APB385784714. | |
| Gefitinib Impurity 13 | Gefitinib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 215659-03-3. Molecular Formula: C9H9NO6. Mole Weight: 227.17. Catalog: APB215659033. | |
| Gefitinib Impurity 15 | Gefitinib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 847949-50-2. Molecular Formula: C22H25ClN4O4. Mole Weight: 444.92. Catalog: APB847949502. | |
| Gefitinib Impurity 19 | Gefitinib Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1803045-02-4. Molecular Formula: C22H24ClFN4O4. Mole Weight: 462.91. Catalog: APB1803045024. | |
| Gefitinib Impurity 2 | Cas No. 675126-26-8. | |
| Gefitinib Impurity 23 | Gefitinib Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 675126-28-0. Molecular Formula: C15H20N2O3. Mole Weight: 276.34. Catalog: APB675126280. | |
| Gefitinib Impurity 24 | Gefitinib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 194423-17-1. Molecular Formula: C10H12N4. Mole Weight: 188.23. Catalog: APB194423171. | |
| Gefitinib Impurity 25 | Gefitinib Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 214472-41-0. Molecular Formula: C16H24N2O5. Mole Weight: 324.38. Catalog: APB214472410. | |
| Gefitinib Impurity 26 | Gefitinib Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 193552-54-4. Molecular Formula: C18H16O6. Mole Weight: 328.32. Catalog: APB193552544. | |
| Gefitinib Impurity 28 | Gefitinib Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1379208-77-1. Molecular Formula: C8H6N2O4. Mole Weight: 194.15. Catalog: APB1379208771. | |
| Gefitinib impurity 29 | Gefitinib impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine. CAS No. 184475-35-2. Molecular Formula: C22H24ClFN4O3. Mole Weight: 446.9. Catalog: APB184475352. | |
| Gefitinib Impurity 3 | Grades: > 95%. Molecular formula: C15H22N2O5. Mole weight: 310.35. | |
| Gefitinib Impurity 3 | Gefitinib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 52805-46-6. Molecular Formula: C8H7NO2. Mole Weight: 149.15. Catalog: APB52805466. | |
| Gefitinib Impurity 30 | Gefitinib Impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2347417-64-3. Molecular Formula: C28H42N4O6S2. Mole Weight: 594.79. Catalog: APB2347417643. | |
| Gefitinib Impurity 31 | Gefitinib Impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 692059-41-9. Molecular Formula: C12H12Cl2N2O2. Mole Weight: 287.14. Catalog: APB692059419. | |
| Gefitinib Impurity 32 | Gefitinib Impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 72235-56-4. Molecular Formula: C7H7ClFN. Mole Weight: 159.59. Catalog: APB72235564. | |
| Gefitinib Impurity 33 | Gefitinib Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 847949-54-6. Molecular Formula: C21H22ClFN4O4. Mole Weight: 448.88. Catalog: APB847949546. | |
| Gefitinib Impurity 34 | Gefitinib Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(3-chloropropoxy)-4-methoxybenzonitrile. CAS No. 1315512-60-7. Molecular Formula: C11H12ClNO2. Mole Weight: 225.67. Catalog: APB1315512607. | |
| Gefitinib Impurity 35 | Gefitinib Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 861453-12-5. Molecular Formula: C15H20N2O6. Mole Weight: 324.33. Catalog: APB861453125. | |
| Gefitinib Impurity 35 | Gefitinib Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(3-bromopropoxy)-4-methoxy-2-nitrobenzonitrile. CAS No. 1325726-60-0. Molecular Formula: C11H11BrN2O4. Mole Weight: 315.12. Catalog: APB1325726600. | |
| Gefitinib Impurity 36 | Gefitinib Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 861453-11-4. Molecular Formula: C15H21NO4. Mole Weight: 279.34. Catalog: APB861453114. | |
| Gefitinib Impurity 37 | Gefitinib Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21397-08-0. Molecular Formula: C6H5ClFN. Mole Weight: 145.56. Catalog: APB21397080. | |
| Gefitinib Impurity 38 | Gefitinib Impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2106-4-9. Molecular Formula: C6H5ClFN. Mole Weight: 145.56. Catalog: APB2106049. | |
| Gefitinib Impurity 39 | Gefitinib Impurity 39. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58749-47-6. Molecular Formula: C8H7NO5. Mole Weight: 197.15. Catalog: APB58749476. | |
| Gefitinib Impurity 4 | Gefitinib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 385784-68-9. Molecular Formula: C12H15N3O2. Mole Weight: 233.27. Catalog: APB385784689. | |
| Gefitinib Impurity 40 | Gefitinib Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 6702-50-7. Molecular Formula: C9H10O4. Mole Weight: 182.18. Catalog: APB6702507. | |
| Gefitinib Impurity 43 | Gefitinib Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(3-chloropropoxy)-4-methoxy-2-nitrobenzaldehyde. CAS No. 1072107-50-6. Molecular Formula: C11H12ClNO5. Mole Weight: 273.67. Catalog: APB1072107506. | |
| Gefitinib Impurity 43 | Gefitinib Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3863-11-4. Molecular Formula: C6H5F2N. Mole Weight: 129.11. Catalog: APB3863114. | |
| Gefitinib Impurity 44 | Gefitinib Impurity 44. Uses: For analytical and research use. Group: Impurity standards. CAS No. 675126-26-8. Molecular Formula: C15H19N3O5. Mole Weight: 321.33. Catalog: APB675126268. | |
| Gefitinib Impurity 45 | Gefitinib Impurity 45. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-7-methoxyquinazoline. CAS No. 205584-69-6. Molecular Formula: C9H6Cl2N2O. Mole Weight: 229.06. Catalog: APB205584696. | |
| Gefitinib Impurity 48 | Gefitinib Impurity 48. Uses: For analytical and research use. Group: Impurity standards. CAS No. 385784-72-5. Molecular Formula: C15H21N3O3. Mole Weight: 291.35. Catalog: APB385784725. | |
| Gefitinib Impurity 5 | Gefitinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 675126-27-9. Molecular Formula: C15H21N3O3. Mole Weight: 291.35. Catalog: APB675126279. | |
| Gefitinib Impurity 6 | Gefitinib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2089650-13-3. Molecular Formula: C22H24Cl2N4O3. Mole Weight: 463.36. Catalog: APB2089650133. | |
| Gefitinib Impurity 7 | Gefitinib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1608115-59-8. Molecular Formula: C22H23ClFN3O4. Mole Weight: 447.89. Catalog: APB1608115598. | |
| Gefitinib Impurity 70 | Gefitinib Impurity 70. Uses: For analytical and research use. Group: Impurity standards. CAS No. 199327-59-8. Molecular Formula: C16H20ClN3O3. Mole Weight: 337.8. Catalog: APB199327598. | |
| Gefitinib Impurity 72 | Gefitinib Impurity 72. Uses: For analytical and research use. Group: Impurity standards. CAS No. 179688-02-9. Molecular Formula: C11H10N2O4. Mole Weight: 234.21. Catalog: APB179688029. | |
| Gefitinib Impurity 73 | Gefitinib Impurity 73. Uses: For analytical and research use. Group: Impurity standards. CAS No. 80547-65-5. Molecular Formula: C8H7NO6. Mole Weight: 213.15. Catalog: APB80547655. | |
| Gefitinib Impurity 8 | Gefitinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 214472-37-4. Molecular Formula: C16H22N2O7. Mole Weight: 354.36. Catalog: APB214472374. | |
| Gefitinib Impurity 9 | Gefitinib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1640351-46-7. Molecular Formula: C15H22N2O5. Mole Weight: 310.35. Catalog: APB1640351467. | |
| Gefitinib impurity C | Gefitinib impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide. CAS No. 847949-51-3. Molecular Formula: C22H24ClFN4O4. Mole Weight: 462.9. Catalog: APB847949513. | |
| Gefitinib impurity F | Gefitinib impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 153437-78-6. Molecular Formula: C16H13ClFN3O2. Mole Weight: 333.74. Catalog: APB153437786. | |
| Gefitinib impurity G | Gefitinib impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((3-chloro-4-fluorophenyl)amino)-6-(3-morpholinopropoxy)quinazolin-7-ol. CAS No. 847949-49-9. Molecular Formula: C21H22ClFN4O3. Mole Weight: 432.88. Catalog: APB847949499. | |
| Gefitinib Impurity G | Gefitinib Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 50413-44-0. Molecular Formula: C9H11NO4. Mole Weight: 197.19. Catalog: APB50413440. | |
| Gefitinib impurity H | Gefitinib impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one. CAS No. 199327-61-2. Molecular Formula: C16H21N3O4. Mole Weight: 319.36. Catalog: APB199327612. | |
| Gefitinib Impurity HCl | Synonyms: 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluoro Gefitinib HCl. Grades: > 95%. Molecular formula: C22H25Cl2FN4O3. Mole weight: 483.37. | |
| Gefitinib impurity I | Gefitinib impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)amino)ethan-1-ol. CAS No. 847949-56-8. Molecular Formula: C20H22ClFN4O3. Mole Weight: 420.87. Catalog: APB847949568. | |
| Gefitinib Impurity I | Grades: > 95%. Molecular formula: C29H37ClFN5O4. Mole weight: 574.10. | |
| Gefitinib Impurity II | Synonyms: N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine. Grades: > 95%. CAS No. 153437-78-6. Molecular formula: C16H13ClFN3O2. Mole weight: 333.75. | |
| Gefitinib Impurity IV | Grades: > 95%. Molecular formula: C22H24Cl2N4O3. Mole weight: 463.37. | |
| Gefitinib impurity K | Gefitinib impurity K. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile. CAS No. 1006378-06-8. Molecular Formula: C15H19N3O5. Mole Weight: 321.33. Catalog: APB1006378068. | |
| Gefitinib Impurity K | Gefitinib Impurity K. Uses: For analytical and research use. Group: Impurity standards. CAS No. 367-21-5. Molecular Formula: C6H5ClFN. Mole Weight: 145.56. Catalog: APB367215. | |
| Gefitinib impurity L | Gefitinib impurity L. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzamide. CAS No. 246512-44-7. Molecular Formula: C15H23N3O4. Mole Weight: 309.36. Catalog: APB246512447. | |
| Gefitinib impurity O | Gefitinib impurity O. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzamide. CAS No. 861453-16-9. Molecular Formula: C15H21N3O6. Mole Weight: 339.34. Catalog: APB861453169. | |
| Gefitinib Impurity P | Gefitinib Impurity P. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine. CAS No. 1502829-45-9. Molecular Formula: C29H37ClFN5O4. Mole Weight: 574.09. Catalog: APB1502829459. | |
| Gefitinib Impurity TE | Gefitinib Impurity TE. Uses: For analytical and research use. Group: Impurity standards. CAS No. 184475-68-1. Molecular Formula: C22H25ClF2N4O3. Mole Weight: 466.91. Catalog: APB184475681. | |
| Gefitinib Impurity VI | Gefitinib Impurity VI is Gefitinib intermediate. Synonyms: 4-(3-Chloropropyl)morpholine; 1-Chloro-3-morpholinopropane; 3-(Morpholin-4-yl)propyl Chloride; 3-Chloro-1-(morpholin-4-yl)propane; 3-Morpholinopropyl Chloride; NSC 28831; NSC 38889; N-(3-Chloropropyl)morpholine. Grades: > 95%. CAS No. 7357-67-7. Molecular formula: C7H14ClNO. Mole weight: 163.65. | |
| Gefitinib Impurity VII | An impurity of Gefitinib. Gefitinib is an EGFR inhibitor. It is used for the treatment of certain breast, lung and other cancers. Synonyms: 3,4-Dihydro-4-oxo-6-acetoxy-7-methoxyquinazoline; 6-(Acetyloxy)-7-methoxy-4(3H)-quinazolinone; 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate; Gefitinib interMidiate IV; 7-Methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate. Grades: > 95%. CAS No. 179688-53-0. Molecular formula: C11H10N2O4. Mole weight: 234.21. | |
| Gefitinib Impurity VIII | Synonyms: 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol 6-acetate; 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate; 6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-, 6-acetate; Gefitinib intermediate VI. Grades: > 95%. CAS No. 788136-89-0. Molecular formula: C17H13ClFN3O3. Mole weight: 361.76. | |
| Gefitinib Impurity X | Synonyms: 6-Acetoxy-4-chloro-7-methoxyquinazoline; 4-Chloro-6-acetoxy-7-methoxyquinazoline; 4-Chloro-7-methoxy-6-quinazolinol 6-acetate; Gefitinib interMediate V; 6-Quinazolinol, 4-chloro-7-Methoxy-, 6-acetate; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropox. Grades: > 95%. CAS No. 230955-75-6. Molecular formula: C11H9ClN2O3. Mole weight: 252.66. | |
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