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GDP-b-L-glucose ammonium salt is an extensively employed compound, serving as a pivotal tool for examining enzymatic activities and metabolic pathways linked to glucose. This product facilitates profound insights into the intricate mechanisms underlying glucose-related disorders, including diabetes. Synonyms: Guanosine 5'-Diphosphate b-L-glucose ammonium salt; Guanosine 5'-(Trihydrogen Diphosphate) b-L-glucose ammonium salt. Molecular formula: C16H31N7O16P2. Mole weight: 639.40.
GDP-D-galactose
GDP-D-galactose, an indispensable biochemical molecule within the biomedical industry, encompasses a pivotal role in enzymatic reactions. As a substrate for glycosylation-involved enzymes, this vital compound becomes essential for the synthesis of diverse glycoproteins and glycolipids. CAS No. 41432-88-6. Molecular formula: C16H25N5O15P2. Mole weight: 589.4.
GDP-D-glucose phosphorylase
The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-α-D-glucose. Activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose. Group: Enzymes. Enzyme Commission Number: EC 2.7.7.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3290; GDP-D-glucose phosphorylase; EC 2.7.7.78. Cat No: EXWM-3290.
GDP-D-glucose sodium salt
Cas No. 103301-72-0.
GDP-D-Man.2Na
Cas No. 103301-73-1.
GDP-D-mannose diammonium salt
GDP-D-mannose diammonium salt is a pivotal compound within the biomedical field assuming the fundamental position as a forerunner for the synthesis of GDP-mannose. This molecule is crucially engaged in glycosylation mechanisms. Molecular formula: C16H23N5O16P2 N2H8. Mole weight: 639.4.
GDP-D-mannose disodium salt
GDP-D-mannose disodium salt is an invaluable compound, playing a pivotal role in the research of disorders pertaining to compromised glucose metabolism. Functioning as a critical intermediate within biosynthetic pathways, it specifically facilitates the synthesis of sugar nucleotides. Synonyms: Guanosine 5-diphospho-a-D-mannose disodium salt; GDP-Man. CAS No. 103301-73-1. Molecular formula: C16H23N5O16P2Na2. Mole weight: 649.3.
The enzyme is involved in the biosynthesis of the O-polysaccharide repeating unit of the bacterium Escherichia coli serotype O86. Group: Enzymes. Synonyms: WbnK. Enzyme Commission Number: EC 2.4.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2543; GDP-Fuc:β-D-Gal-1,3-α-D-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,2-fucosyltransferase; EC 2.4.1.308; WbnK. Cat No: EXWM-2543.
GDP-Gel / GDP-Agarose
GDP-Gel is the GDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of fucosyltransferases. Synonyms: Guanosine- 5'- O- diphosphate, immobilized on a polymeric matrix.
GDP-glucosidase
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. Group: Enzymes. Synonyms: guanosine diphosphoglucosidase; guanosine diphosphate D-glucose glucohydrolase. Enzyme Commission Number: EC 3.2.1.42. CAS No. 37288-36-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3905; GDP-glucosidase; EC 3.2.1.42; 37288-36-1; guanosine diphosphoglucosidase; guanosine diphosphate D-glucose glucohydrolase. Cat No: EXWM-3905.
GDP-L-colitose synthase
The enzyme is involved in biosynthesis of L-colitose, a 3,6-dideoxyhexose found in the O-antigen of Gram-negative lipopolysaccharides, where it catalyses the reaction in the reverse direction. The enzyme also performs the NAD(P)H-dependent epimerisation at C-5 of the sugar. The enzyme from Yersinia pseudotuberculosis is Si-specific with respect to NAD(P)H. Group: Enzymes. Synonyms: ColC. Enzyme Commission Number: EC 1.1.1.356. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0272; GDP-L-colitose synthase; EC 1.1.1.356; ColC. Cat No: EXWM-0272.
GDP-L-Fuc.2Na
Cas No. 15839-70-0.
GDP-L-fucose
GDP-L-fucose is a pivotal biomolecule acting as a precursory compound to facilitate the synthesis of fucose-containing glycoconjugates implicated in diverse cellular phenomena. Its exceptional significance lies in the research of glycosylation patterns, evaluation of protein functioning repercussions and investigation into possible therapeutic approaches targeting conditions like cancer and inflammation. Synonyms: GDP-b-L-fucose; Guanosine 5-diphospho-b-L-fucose; GDP-Fucose; Guanosine diphosphofucose; Guanosine 5'-diphospho-beta-L-fucopyranose; guanosine 5'-[3-(6-deoxy-beta-L-galactopyranosyl) dihydrogen diphosphate]. Grades: ≥90%. CAS No. 15839-70-0. Molecular formula: C16H25N5O15P2. Mole weight: 589.34.
GDP-L-fucose diammonium salt
GDP-L-fucose diammonium salt is an indispensable compound, serving as a vital substrate for fucosyltransferase. This compound intricately contributes to the biosynthesis of fucosylated glycans. Molecular formula: C15H23N5O15P2 N2H8. Mole weight: 623.41.
GDP-L-fucose disodium salt - low endotoxin grade is a remarkably valuable compound within the biomedical realm, used for studying an array of ailments intertwined with cell surface glycans. By functioning as a precursor in fucosylated carbohydrate synthesis, it assumes an indispensable role in facilitating vital cellular adhesion and signaling mechanisms. Molecular formula: C16H23N5O15P2Na2. Mole weight: 633.31.
GDP-L-fucose synthase
Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent. Group: Enzymes. Synonyms: GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing). Enzyme Commission Number: EC 1.1.1.271. CAS No. 113756-18-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0178; GDP-L-fucose synthase; EC 1.1.1.271; 113756-18-6; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing). Cat No: EXWM-0178.
GDP-L-galactose phosphorylase
The enzyme catalyses a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Group: Enzymes. Synonyms: VTC2; VTC5. Enzyme Commission Number: EC 2.7.7.69. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3280; GDP-L-galactose phosphorylase; EC 2.7.7.69; VTC2; VTC5. Cat No: EXWM-3280.
GDP-L-galactose sodium salt
GDP-L-galactose sodium salt, an indispensable element in the field of biomedicine, assumes a pivotal function in the amalgamation of Vitamin C, thereby facilitating the amelioration of scurvy and associated ailments. This efficacious product showcases its potential in enhancing general well-being and mitigating deficiencies stemming from insufficient levels of Vitamin C. Synonyms: Guanosine 5-diphosphate-L-galactose. CAS No. 6815-91-4. Molecular formula: C16H23N5O16P2Na2. Mole weight: 649.30.
GDP - lyophilized
Guanosine 5'-diphosphate could be used to study cell signaling related to G-coupled protein receptors as well as some GTPases. Synonyms: Guanosine-5'-diphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. CAS No. 43139-22-6. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid).
The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation of D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation (cf. EC 2.4.1.257), to form the first branched pentasaccharide intermediate of the dolichol pathway. Group: Enzymes. Synonyms: Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); glycolipid 3-α-mannosyltransferase; GDP-mannose:glycolipid 3-&alph. Enzyme Commission Number: EC 2.4.1.132. CAS No. 81181-76-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2357; GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase; EC 2.4.1.132; 81181-76-2; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); glycolipid 3-α-mannosyltransferase; GDP-mannose:glycolipid 3-α-D-mannosyltransferase; GDP-Man:Man1GlcNAc2-PP-Dol α-1,3-mannosyltransferase; GDP-D-mannose:D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol 3-α-mannosyltransferase. Cat No: EXWM-2357.
The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation (cf. EC 2.4.1.132) of β-D-Man-(1?4)-β-D-GlcNAc-(1?4)-α-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation, to form the first branched pentasaccharide intermediate of the dolichol pathway. Group: Enzymes. Synonyms: GDP-Man:Man2GlcNAc2-PP-Dol α-1,6-mannosyltransferase; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); GDP-Man:Man1GlcNAc2-PP-dolichol mannosyltransfera. Enzyme Commission Number: EC 2.4.1.257. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2487; GDP-Man:Man2GlcNAc2-PP-dolichol α-1,6-mannosyltransferase; EC 2.4.1.257; GDP-Man:Man2GlcNAc2-PP-Dol α-1,6-mannosyltransferase; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); GDP-Man:Man1GlcNAc2-PP-dolichol mannosyltransferase (ambiguous); GDP-D-mannose:D-Man-α-(1?3)-D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol α-6-mannosyltransferase. Cat No: EXWM-2487.
The biosynthesis of asparagine-linked glycoproteins (N-linked protein glycosylation) utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. ALG11 mannosyltransferase from Saccharomyces cerevisiae carries out two sequential steps in the formation of the lipid-linked core oligosaccharide, adding two mannose residues in α(1?2) linkages to the nascent oligosaccharide. Group: Enzymes. Synonyms: ALG11; AL. Enzyme Commission Number: EC 2.4.1.131. CAS No. 74506-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2356; GDP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase; EC 2.4.1.131; 74506-43-7; ALG11; ALG11 mannosyltransferase; LEW3 (gene name); At2G40190 (gene name); gmd3 (gene name); galactomannan deficiency protein 3; GDP-mannose:glycolipid 1,2-α-D-mannosyltransferase; glycolipid 2-α-mannosyltransferase; GDP-mannose:glycolipid 2-α-D-mannosyltransferase; GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase; GDP-α-D-mannose:D-Man-α-(1?3)-[D-Man-α-(1?6)]-D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol 2-α-D-mannosyltransferase. Cat No: EXWM-2356.
GDP-mannose 3,5-epimerase
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. This enzyme participates in ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: GDP-D-mannose:GDP-L-galactose epimerase; guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase. Enzyme Commission Number: EC 5.1.3.18. CAS No. 72162-82-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5403; GDP-mannose 3,5-epimerase; EC 5.1.3.18; 72162-82-4; GDP-D-mannose:GDP-L-galactose epimerase; guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase. Cat No: EXWM-5403.
GDP-mannose 4,6-dehydratase
The bacterial enzyme requires bound NAD+. This enzyme forms the first step in the biosynthesis of GDP-α-D-rhamnose and GDP-β-L-fucose. In Aneurinibacillus thermoaerophilus L420-91T, this enzyme acts as a bifunctional enzyme, catalysing the above reaction as well as the reaction catalysed by EC 1.1.1.281, GDP-4-dehydro-6-deoxy-D-mannose reductase. Belongs to the short-chain dehydrogenase/reductase enzyme family, having homologous structures and a conserved catalytic triad of Lys, Tyr and Ser/Thr residues. Group: Enzymes. Synonyms: guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-. Enzyme Commission Number: EC 4.2.1.47. CAS No. 37211-59-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5036; GDP-mannose 4,6-dehydratase; EC 4.2.1.47; 37211-59-9; guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Cat No: EXWM-5036.
GDP-mannose 6-dehydrogenase
Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate. Group: Enzymes. Synonyms: guanosine diphosphomannose dehydrogenase; GDP-mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase. Enzyme Commission Number: EC 1.1.1.132. CAS No. 37250-63-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0036; GDP-mannose 6-dehydrogenase; EC 1.1.1.132; 37250-63-8; guanosine diphosphomannose dehydrogenase; GDP-mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase. Cat No: EXWM-0036.
In the bacterium Gluconacetobacter xylinus (previously known as Acetobacter xylinum) the enzyme is involved in the biosynthesis of the exopolysaccharide acetan. In Xanthomonas campestris the enzyme is involved in the biosynthesis of the exopolysaccharide xanthan. Group: Enzymes. Synonyms: GumH; AceA; α1,3-mannosyltransferase AceA. Enzyme Commission Number: EC 2.4.1.252. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2482; GDP-mannose:cellobiosyl-diphosphopolyprenol α-mannosyltransferase; EC 2.4.1.252; GumH; AceA; α1,3-mannosyltransferase AceA. Cat No: EXWM-2482.
GDP-Mannose pyrophosphorylase from Pyrococcus furiosus, Recombinant
In enzymology, a mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) is an enzyme that catalyzes the chemical reaction: GTP + alpha-D-mannose 1-phosphate ? diphosphate + GDP-mannose. Thus, the two substrates of this enzyme are GTP and alpha-D-mannose 1-phosphate, whereas its two products are diphosphate and GDP-mannose. Group: Enzymes. Synonyms: GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Enzyme Commission Number: EC 2.7.7.13. CAS No. 37278-24-3. Purity: min 95% by SDS-PAGE. GDP-Mannose pyrophosphorylase. Source: E. coli. Species: Pyrococcus furiosus. GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Cat No: NATE-1504.
GDP-perosamine N-acetyltransferase
D-Perosamine is one of several dideoxy sugars found in the O-antigen component of the outer membrane lipopolysaccharides of Gram-negative bacteria. Group: Enzymes. Synonyms: perB (gene name); GDP-α-D-perosamine N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.227. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2174; GDP-perosamine N-acetyltransferase; EC 2.3.1.227; perB (gene name); GDP-α-D-perosamine N-acetyltransferase. Cat No: EXWM-2174.
GDP-perosamine synthase
A pyridoxal 5'-phosphate enzyme. D-Perosamine is one of several dideoxy sugars found in the O-specific polysaccharide of the lipopolysaccharide component of the outer membrane of Gram-negative bacteria. The enzyme catalyses the final step in GDP-α-D-perosamine synthesis. Group: Enzymes. Synonyms: RfbE; GDP-4-keto-6-deoxy-D-mannose-4-aminotransferase; GDP-perosamine synthetase; PerA; GDP-4-amino-4,6-dideoxy-α-D-mannose:2-oxoglutarate aminotransferase. Enzyme Commission Number: EC 2.6.1.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2842; GDP-perosamine synthase; EC 2.6.1.102; RfbE; GDP-4-keto-6-deoxy-D-mannose-4-aminotransferase; GDP-perosamine synthetase; PerA; GDP-4-amino-4,6-dideoxy-α-D-mannose:2-oxoglutarate aminotransferase. Cat No: EXWM-2842.
GDP polyribonucleotidyltransferase
The enzyme from rhabdoviruses transfers 5'-monophosphorylated (p-)mRNA from 5'-triphosphorylated (ppp-)mRNA to GDP to form 5'-capped mRNA (GpppmRNA) in a viral mRNA-start sequence-dependent manner. The (p-)mRNA transfer reaction proceeds through a covalent enzyme-pmRNA intermediate. Group: Enzymes. Enzyme Commission Number: EC 2.7.7.88. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3301; GDP polyribonucleotidyltransferase; EC 2.7.7.88. Cat No: EXWM-3301.
GE20372 A
GE20372 A, a tetrapeptide, is produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Synonyms: GE20372 Factor A; GE-20372A; (1(S),2(S))-N2-(((1-Carboxy-2-(4-hydroxyphenyl)ethyl)amino)carbonyl)-L-arginyl-N-(1-formyl-2-phenylethyl)-L-valinamide. CAS No. 163565-75-1. Molecular formula: C30H41N7O7. Mole weight: 611.69.
GE20372 B
GE20372 B is a tetrapeptide produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Molecular formula: C30H41N7O7. Mole weight: 611.69.
GE 2270A
GE 2270A is a thiopeptide antibiotic produced by the strain of Planobispora rosea. It inhibits bacterial protein synthesis and has anti-Gram-positive aerobic and anaerobic bacteria (MIC = 0.03-0.25 μg/mL) and Mycobacterium tuberculosis (MIC = 1 μg/mL) activities. Synonyms: Antibiotic GE 2270A; MDL 62879; Antibiotic MDL 62879; GE-2270A; GE-2270. CAS No. 134861-34-0. Molecular formula: C56H55N15O10S6. Mole weight: 1290.52.
GE 23077A1
A cyclic peptide antibiotic isolated from actinomadura sp. strain GE23077. It inhibits bacterial RNA polymerase. Synonyms: Antibiotic GE 23077A1; GE-23077-A1. CAS No. 435344-49-3. Molecular formula: C31H49N9O16. Mole weight: 803.77.
Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα , PI3Kγ , and mTOR with IC 50 s of 0.4 nM, 5.4 nM and 1.6 nM, respectively [1]. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PKI-587; PF-05212384. CAS No. 1197160-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10681.
Gedatolisib (PF-05212384, PKI-587)
Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM, respectively. Phase 2. Synonyms: PKI587; PKI-587; PKI 587; PF05212384; PF-05212384; PF 05212384; PF5212384; PF-5212384; PF 5212384; Gedatolisib. Grades: >98%. CAS No. 1197160-78-3. Molecular formula: C32H41N9O4. Mole weight: 615.73.
Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Grades: >98%. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57.
Gedunin
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57. Purity: 0.98. Product ID: ACM2753302. Alfa Chemistry ISO 9001:2015 Certified.
Gedunin
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research [3]. Uses: Scientific research. Group: Natural products. CAS No. 2753-30-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107577.
Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. It is under a clinical trial for the treatment of chronic cough. Synonyms: AF-219; MK-7264. CAS No. 1015787-98-0. Molecular formula: C14H19N5O4S. Mole weight: 353.4.
Gefapixant
Gefapixant. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1015787-98-0. Molecular Formula: C14H19N5O4S. Mole Weight: 353.4. Catalog: APB1015787980.
Gefapixant
Gefapixant is an orally active and potent purinergic P2X3 receptor ( P2X3R ) antagonist, with IC 50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7264; AF-219. CAS No. 1015787-98-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588.
Gefapixant citrate
Gefapixant citrate is an orally active and potent purinergic P2X3 receptor ( P2X3R ) antagonist, with IC 50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7264 citrate; AF-219 citrate. CAS No. 2310299-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588A.
Gefapixant Impurity 1
Gefapixant Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 865304-71-8. Molecular Formula: C14H18N4O2. Mole Weight: 274.32. Catalog: APB865304718.
Gefapixant Impurity 2
Gefapixant Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2413718-92-8. Molecular Formula: C14H18N4O4S. Mole Weight: 338.38. Catalog: APB2413718928.
Gefapixant Impurity 7
Gefapixant Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2527107-23-7. Molecular Formula: C20H25N5O3. Mole Weight: 383.45. Catalog: APB2527107237.
Gefapixant Impurity 8
Gefapixant Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2527107-24-8. Molecular Formula: C20H25N5O3. Mole Weight: 383.45. Catalog: APB2527107248.
Gefarnate
Gefarnate is a drug used for the treatment of gastritis and gastric ulcer, in vivo, the instillation of gefarnate reduced corneal epithelial damage from desiccation in a dose-dependent fashion. Besides Gefarnate has been proposed for use in the treatment of dry eye syndrome. Synonyms: [(2E)-3,7-dimethylocta-2,6-dienyl] (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate; Farnesylacetate, Geranyl; Gefarnate; Gefarnil; Gepharnate; Geranyl Farnesylacetate; Ulco. CAS No. 51-77-4. Molecular formula: C27H44O2. Mole weight: 400.64.
Gefarnate
Gefarnate. Group: Biochemicals. Alternative Names: Geranyl farnesylacetate. Grades: Highly Purified. CAS No. 51-77-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C27H44O2. US Biological Life Sciences.
Worldwide
Gefarnate
Gefarnate is a agent used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome. Uses: Scientific research. Group: Signaling pathways. CAS No. 51-77-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B2206.
Gefitinib
Gefitinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 184475-35-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C22H24ClFN4O3. US Biological Life Sciences.
Gefitinib. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Chloro-6-[3-(4-morpholinyl)propoxy]-4-quinazoline;4-Chloro-7-methoxy-6-(3-morpholinopropoxy)quinazoline;4-Chloro-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazoline. Product Category: Heterocyclic Organic Compound. CAS No. 199327-59-8. Molecular formula: C16H20ClN3O3. Mole weight: 0. Product ID: ACM199327598. Alfa Chemistry ISO 9001:2015 Certified.
Gefitinib
Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer [1] [2] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD1839. CAS No. 184475-35-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895.
Gefitinib
100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C22H24ClFN4O3. CAS No. 184475-35-2. Prepack ID 57220562-100mg. Molecular Weight 446.9. See USA prepack pricing.
Labeled Gefitinib. Gefitinib is an antineoplastic. Group: Biochemicals. Alternative Names: N-(3-Chloro-4-fluorophenyl)-7-(methoxy-d3)-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; Iressa-d3; ZD 1839-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gefitinib-D6
Gefitinib-D6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1228664-49-0. Molecular Formula: C22H18D6ClFN4O3. Mole Weight: 452.94. Catalog: APB1228664490.
Gefitinib-D8
Gefitinib-D8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 857091-32-8. Molecular Formula: 22H16D8ClFN4O3. Mole Weight: 454.96. Catalog: APB857091328.
Gefitinib Difluoro Impurity
Gefitinib Difluoro Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 184475-50-1. Molecular Formula: C22H24F2N4O3. Mole Weight: 430.46. Catalog: APB184475501.
Gefitinib Dihydrochloride
Gefitinib Dihydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 184475-56-7. Molecular Formula: C22H26Cl3FN4O3. Mole Weight: 519.82. Catalog: APB184475567.
Gefitinib EP Impurity B
Gefitinib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1603814-04-5. Molecular Formula: C22H24ClFN4O3. Mole Weight: 446.91. Catalog: APB1603814045.