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It can be used in biological study in influence of plant growth regulators on shoot proliferation and secondary metabolite production in micropropagated Huernia hystrix. Synonyms: N6-(m-Methoxybenzyl)adenosine; Mem-TR; 6-(3-Methoxybenzylamino)-9-b-D-ribofuranosylpurine; N6-(3-Methoxybenzyl)adenosine; N-(3-Methoxybenzyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; meta-Methoxytopolin Riboside; N-[(3-Methoxyphenyl)methyl]adenosine. Grades: ≥95%. CAS No. 101565-95-1. Molecular formula: C18H21N5O5. Mole weight: 387.39.
m-Methyl Atomoxetine Hydrochloride
m-Methyl Atomoxetine Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-γ - (3-methylphenoxy) benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride. Grades: Highly Purified. CAS No. 873310-28-2. Pack Sizes: 2.5mg. Molecular Formula: C17H22ClNO, Molecular Weight: 291.82. US Biological Life Sciences.
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m-Methyl Atomoxetine Hydrochloride
M-Methyl Atomoxetine Hydrochloride is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: N-Methyl-γ-(3-methylphenoxy)benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride; rac-Atomoxetine EP Impurity D HCl; Atomoxetine USP Related Compound B; N-methyl-3-phenyl-3-(m-tolyloxy)propan-1-amine hydrochloride (1:1). Grades: ≥90%. CAS No. 873310-28-2. Molecular formula: C17H22ClNO. Mole weight: 291.81.
MMF
MMF. Group: Biochemicals. Grades: Purified. CAS No. 2756-87-8. Pack Sizes: 50mg. US Biological Life Sciences.
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MMGP1
MMGP1 is an antifungal peptide which was found to possess potent antifungal activity against C. albicans.
MMK 1
MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 = 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Some findings showed that the transient rise in intracellular free calcium induced by MMK-1 involves both a release of calcium from intracellular stores and an opening of channels in the plasma membrane. Synonyms: MMK 1; MMK1; MMK-1; (4S)-4-[[(2S)-2-amino-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid. CAS No. 271246-66-3. Molecular formula: C75H123N19O18S. Mole weight: 1610.97.
MMK 1
MMK 1. Group: Biochemicals. Grades: Purified. CAS No. 271246-66-3. Pack Sizes: 1mg. US Biological Life Sciences.
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MMP-12 Inhibitor, MMP408 - CAS 1258003-93-8
The MMP-12 Inhibitor, MMP408, also referenced under CAS 1258003-93-8, controls the biological activity of MMP-12. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-13 Inhibitor
MMP-13 Inhibitor is a potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 value of 8 nM. Synonyms: Collagenase-3 Inhibitor; Matrix Metalloproteinase-13 Inhibitor; 4,6-Pyrimidinedicarboxamide; N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide. Grades: ≥98%. CAS No. 544678-85-5. Molecular formula: C22H20F2N4O2. Mole weight: 410.4.
MMP-13 Inhibitor - CAS 544678-85-5
The MMP-13 Inhibitor, also referenced under CAS 544678-85-5, controls the biological activity of MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-13 Substrate, Fluorogenic
A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 10? M?¹s?¹). Group: Fluorescence/luminescence spectroscopy.
MMP-14 Substrate I, Fluorogenic
A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. Group: Fluorescence/luminescence spectroscopy.
MMP-1/MMP-9 Substrate, Fluorogenic
An excellent quenched fluorescence substrate for MMP-1 and MMP-9. Group: Fluorescence/luminescence spectroscopy.
MMP-1 Substrate III, Fluorogenic
An excellent quenched fluorescence substrate for MMP-1. Group: Fluorescence/luminescence spectroscopy.
MMP2-IN-3
MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC 50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8 , with IC 50 values of 26.6, and 32 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 897799-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147746.
MMP-2 Inhibitor I
MMP-2 Inhibitor I is a reversible inhibitor of matrix metalloproteinase 2 (MMP-2) with Ki value of 1.6 μM. It attenuates cancer cell migration via inhibition of MMP-2. Synonyms: ?Matrix Metalloproteinase-2 Inhibitor I; cis-9-Octadecenoyl-N-hydroxylamide; Oleylhydroxamate; N-Hydroxyoleamide; OA-Hy; Oleoyl-N-hydroxylamide. Grades: ≥98%. CAS No. 10335-69-0. Molecular formula: C18H35NO2. Mole weight: 297.5.
MMP-2 Inhibitor I - CAS 10335-69-0
The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2 Inhibitor II
MMP-2 Inhibitor II is an irreversible inhibitor of matrix metalloproteinase-2 (MMP-2) with Ki value of 2.4 μM. It also less potently inhibits MMP-1 and MMP-7. Synonyms: ?Matrix Metalloproteinase-2 Inhibitor II; (4- (4- (Methanesulfonamido) phenoxy) phenylsulfonyl) methyloxirane. Grades: ≥98%. CAS No. 869577-51-5. Molecular formula: C16H17NO6S2. Mole weight: 383.4.
MMP-2 Inhibitor II - CAS 869577-51-5
The MMP-2 Inhibitor II, also referenced under CAS 869577-51-5, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2 Inhibitor III - CAS 704888-90-4
The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2 Inhibitor IV
The MMP-2 Inhibitor IV controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2 Inhibitor IV (Bone Resorption Inhibitor, (4'-chlorobiphenyl-4ylsulfonamido) methylenediphosphonic Acid)
A cell-permeable, bisphosphonate derivative that displays nanomolar activity against MMP-2 (IC50=37nM), with good selectivity over MMP-8 (320nM), MMP-9 (>1uM), and MMP-14 (> 1uM). It is shown to inhibit osteoclast activity in a macrophage cell line, J774 (IC50=1.7uM), which is more potent compared with other bisphosphonates such as Alendronate, (IC50=30uM), and Zolendronate (7.8uM), without observable cytotoxicity in HepG2 cells. At 25uM, it abolishes the formation of actin rings, which are functional structures that are typical of resorbing osteoclasts, at activity levels comparable with those of zolendronic acid, inhibits bone resportion in vitro, and demonstrates cytotoxic properties in murine osteoclasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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MMP-2/MMP-3 Inhibitor III, PD166793 - CAS 199850-67-4
The MMP-2/MMP-3 Inhibitor III, PD166793, also referenced under CAS 199850-67-4, controls the biological activity of MMP-2/MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase ( MMP-9 and MMP-2 ) inhibitor with IC 50 s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193807-58-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116399.
MMP-2/MMP-9 Inhibitor I
MMP-2/MMP-9 inhibitor I is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 310 and 240 nM, respectively. It blocks MMP-2/MMP-9-dependent invasion, tumor growth, and metastasis in both cell culture and mouse tumor models. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor I; 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanoic acid. Grades: ≥99%. CAS No. 193807-58-8. Molecular formula: C21H19NO4S. Mole weight: 381.4.
MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8
The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Inhibitor II
MMP-2/MMP-9 inhibitor II is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 17 and 30 nM, respectively. It was shown to suppress lung colonization of Lewis lung carcinoma cells and inhibit tumor-induced angiogenesis, tumor growth, and liver metastasis in mouse models. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II; (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide. Grades: ≥98%. CAS No. 193807-60-2. Molecular formula: C21H20N2O4S. Mole weight: 396.46.
MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2
The MMP-2/MMP-9 Inhibitor II, also referenced under CAS 193807-60-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Inhibitor III
The MMP-2/MMP-9 Inhibitor III controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Inhibitor III trifluoroacetate salt
MMP-2/MMP-9 inhibitor III is a cyclic peptide inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 10-20 μM for both. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grades: ≥95%. Molecular formula: C52H71N13O14S2·xCF3COOH. Mole weight: 1166.33.
MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2
The MMP-2/MMP-9 Inhibitor IV, also referenced under CAS 292605-14-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Inhibitor V - CAS 869577-53-7
The MMP-2/MMP-9 Inhibitor V, also referenced under CAS 869577-53-7, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Substrate I, Fluorogenic
A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9). Group: Fluorescence/luminescence spectroscopy.
MMP-2/MMP-9 Substrate II
An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Group: Fluorescence/luminescence spectroscopy.
MMP-2 Substrate, Fluorogenic
A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10? M?¹s?¹). Group: Fluorescence/luminescence spectroscopy.
MMP-3 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
MMP-3 Inhibitor
MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with Ki value of 95 nM. Synonyms: Matrix Metalloproteinase-3 Inhibitor; N-acetyl-L-arginyl-L-cysteinyl-glycyl-L-valyl-L-prolyl-L-isoasparagine. Grades: ≥95%. CAS No. 158841-76-0. Molecular formula: C27H46N10O9S. Mole weight: 686.78.
MMP-3 Inhibitor I
The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-3 Inhibitor II - CAS 161314-17-6
The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP-3 Inhibitor VIII
MMP-3 inhibitor VIII is a cell-permeable inhibitor of matrix metalloproteinase-3 (MMP-3) with Ki value of 23 nM. It also inhibits mouse macrophage metalloelastase MME/MMP-12. Synonyms: Matrix Metalloproteinase-3 Inhibitor VIII; Stromelysin-1 Inhibitor VIII; N-Hydroxy-2(R)-{[(4-methoxyphenyl)sulfonyl]-[benzylamino]}-4-methylpentanamide. Grades: ≥95%. CAS No. 208663-26-7. Molecular formula: C20H26N2O5S. Mole weight: 406.5.
MMP-7 Substrate, Fluorogenic
Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 10? M?¹ s?¹). Group: Fluorescence/luminescence spectroscopy.
MMP-8 Inhibitor I
MMP-8 Inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinase-8 (MMP-8) with IC50 value of 4 nM. MMP-8 is a neutrophil collagenase that cleaves interstitial collagens. MMP-8 is associated with diseases including arthritis, cancer, osteoporosis and arteriosclerosis. Synonyms: Matrix Metalloproteinase-8 Inhibitor I; N-hydroxy-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide. Grades: ≥95%. CAS No. 236403-25-1. Molecular formula: C17H18N2O5S. Mole weight: 362.4.
MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC 50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 206549-55-5. Pack Sizes: 500 μg. Product ID: HY-116302.
MMP-9 Inhibitor I
MMP-9 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinase-9 (MMP-9) with IC50 value of 5 nM, respectively. Synonyms: Matrix Metalloproteinase-9 Inhibitor I; 2-[Benzyl(4-methoxyphenylsulfonyl)amino]-3-methyl-5-(diethylaminomethyl)benzohydroximic acid. Grades: ≥95%. CAS No. 1177749-58-4. Molecular formula: C27H33N3O5S. Mole weight: 511.6.
MMP-9 Inhibitor I - CAS 1177749-58-4
MMP-9 Inhibitor I, CAS 1177749-58-4, is a cell-permeable, potent, and reversible MMP-9 Inhibitor (IC?? = 5 nM). At high concentration inhibits MMP-1 (IC?? = 1.05 μM) & MMP-13 (IC?? = 113 nM). Group: Fluorescence/luminescence spectroscopy.
MMP-9 Inhibitor II
The MMP-9 Inhibitor II controls the biological activity of MMP-9. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
MMP-9 Inhibitor II (MMP-9 PEX Inhibitor)
This compound is a cell-permeable, selective, and reversible thiopyrimidone MMP-9 allosteric inhibitor that binds specifically to the non-catalytic site of MMP-9 at the PEX domain with a =2.1uM and thereby disrupts MMP-9 homodimerization and its cross-talk with CD44 and the EGFR-MAPK signaling pathway. It does not bind to the PEX domain of MMP-2 or MT1-MMP and it is shown to decrease MMP-9 mediated cell migration in COS-1 cells at 100uM. Also, it inhibits cell migration and invasion of HT-1080 and MDA-MB-435 human cancer cells in a dose-dependent manner from 0.1 to 100M, without altering MMP-9 expression or proteolytic activity in HT-1080 cells. In addition, it attenuates both primary tumor growth and metastasis in vivo in a mouse model without obvious toxicity (20mg/kg, 6 days/week, i.v. and i.t.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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MMP-9/MMP-13 Inhibitor I
MMP-9/MMP-13 inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinases MMP-9/MMP-13 with IC50 values of 0.9 nM for both. It also less potently inhibits MMP-1, MMP-3, and MMP-7. Synonyms: Matrix Metalloproteinase-9/Matrix Metalloproteinase-13 Inhibitor I; N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide. Grades: ≥98%. CAS No. 204140-01-2. Molecular formula: C25H25N3O6S. Mole weight: 495.6.
MMP-9/MMP-13 Inhibitor I - CAS 204140-01-2
The MMP-9/MMP-13 Inhibitor I, also referenced under CAS 204140-01-2, controls the biological activity of MMP-9/MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Mmpep. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[(3-Methoxyphenyl)ethynyl]-6-methylpyridine Hydrochloride; M-MPEP Hydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 823198-78-3. Molecular formula: C15H14ClNO. Mole weight: 259.73. Purity: 0.96. IUPACName: 2-[2-(3-methoxyphenyl)ethynyl]-6-methylpyridine;hydrochloride. Canonical SMILES: CC1=CC=CC(=N1)C#CC2=CC(=CC=C2)OC.Cl. Product ID: ACM823198783. Alfa Chemistry ISO 9001:2015 Certified. Categories: MMPIP.
MMP Inhibitor I
The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP Inhibitor II
MMP Inhibitor II is an inhibitor of matrix metalloproteinase MMP-1/MMP-3/MMP-7/MMP-9 with IC50 values of 24, 18.4, 30 and 2.7 nM, respectively. Synonyms: Matrix Metalloproteinase Inhibitor II; NHDDPC; PG 117025; PGE 4410186; N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl-1,3-diazinane-2-carboxamide. Grades: ≥95%. CAS No. 203915-59-7. Molecular formula: C21H27N3O8S2. Mole weight: 513.6.
MMP Inhibitor II
MMP Inhibitor II (compound 4e) is a potent, reversible pan- MMP inhibitor with IC 50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 203915-59-7. Pack Sizes: 1 mg. Product ID: HY-119423.
MMP Inhibitor II - CAS 203915-59-7
The MMP Inhibitor II, also referenced under CAS 203915-59-7, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP Inhibitor III - CAS 927827-98-3
The MMP Inhibitor III, also referenced under CAS 927827-98-3, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMP Inhibitor I trifluoroacetate salt
MMP inhibitor I is an inhibitor of matrix metalloproteinase MMP-1/MMP-2/MMP-3 with IC50 values of 1.3, 30, and 150 μM, respectively. Synonyms: FN 439; Matrix Metalloproteinase Inhibitor I. Grades: ≥95%. Molecular formula: C23H35N6O6·xCF3COOH. Mole weight: 491.56.
MMP Inhibitor V - CAS 223472-31-9
The MMP Inhibitor V, also referenced under CAS 223472-31-9, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
MMPIP hydrochloride is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 = 26 and 610 nM). MMPIP also exhibits intrinsic activity and acts as an inverse agonist. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride. Grades: ≥98% by HPLC. CAS No. 479077-02-6. Molecular formula: C19H15N3O3. Mole weight: 333.3.
A potent negative allosteric modulator highly selective for mGlu7 receptors (IC50 = 15nM). No effect on other subtype mGlu receptors. Frequently used in studies of alcohol and cocaine addition, depression, anxiety and stress related disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 479077-02-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MMPIP hydrochloride
MMPIP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 479077-02-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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MMPIP hydrochloride
MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It was demonstrated to reduce pain responses and affective/cognitive impairments in neuropathic pain conditions. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-C]pyridin-4(5H)-one hydrochloride. Grades: ≥98%. CAS No. 1215566-78-1. Molecular formula: C19H15N3O3·HCl. Mole weight: 369.8.
MMPIP hydrochloride
MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 ( mGluR7 ) selective antagonist ( K B values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215566-78-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103111.
MMPSI
MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC 50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220509-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103346.