A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MM 11253 is a RARγ antagonist. It can block the growth inhibitory ability of RARγ-selective agonists in squamous cell carcinoma (SCC)-25 cells. Synonyms: MM 11253; MM-11253; MM11253. 6-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthalenecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 345952-44-5. Molecular formula: C28H30O2S2. Mole weight: 462.67.
MM 14201
It is produced by the strain of Streptomyces sp. NCIB 11813. MM 14201 has a broad spectrum of antibacterial activity, especially against the bacteria of Serratia and Pseudomonas. Synonyms: MM-14201; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 3-amino-5-hydroxy-, (1S-(1alpha,5beta,6alpha))-. CAS No. 89020-30-4. Molecular formula: C6H7NO3. Mole weight: 141.12.
MM-17880
MM-17880 is originally isolated from Streptomyces olivaceus. It has anti-gram-positive and anti-gram-negative bacteria activities. Combined with amoxycillin, it has a synergistic antibacterial effect on Staphylococcus aureus and Klebsiella pneumoniae. Synonyms: (5R)-3-[[2-(Acetylamino)ethyl]thio]-6α-[(S)-1-(sulfooxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid disodium salt. CAS No. 61036-81-5. Molecular formula: C13H16N2Na2O8S2. Mole weight: 438.38.
MM-206
MM-206 is a cell-permeable STAT3 inhibitor. Synonyms: 2,3,4,5,6-Pentafluoro-N-(4-hydroxy-3-phenylsulfanylnaphthalen-1-yl)benzenesulfonamide. Grades: ≥98%. CAS No. 1809581-87-0. Molecular formula: C22H12F5NO3S2. Mole weight: 497.5.
MM-22
MM-22 is a biotinylated anandamide analog. It can block anandamide uptake with IC50 value of 0.5 μM in HaCaT cells. Synonyms: MM-22; MM 22; MM22; (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[2-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide. Grades: ≥98% by HPLC. CAS No. 956605-71-3. Molecular formula: C36H60N4O5S. Mole weight: 660.95.
Mm 2,4-dimercapto-5,6-diaminopyrimidine
Mm 2,4-dimercapto-5,6-diaminopyrimidine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 31295-41-7. Molecular Formula: C4H6N4S2. Mole Weight: 174.24. Catalog: APB31295417.
MM-401 TFA
MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity ( IC 50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1442106-11-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-19554A.
MM-419447 (Linaclotide Metabolite) Trifluoroacetic acid is a metabolite of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used to treat abdominal pain associated with constipation in patients with irritable bowel syndrome (IBS). Synonyms: L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine trifluoroacetic acid; L-Cysteine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, trifluoroacetic acid (1:x); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-OH.TFA. Grades: 97%. Molecular formula: C50H76N14O19S6.xC2HF3O2. Mole weight: 1369.61 (free base).
MM 42842
MM 42842 is originally isolated from Pseudomonas cocovenenans and has weak activity against gram-positive bacteria. Synonyms: MM-42842. Grades: >98%. CAS No. 113784-28-4. Molecular formula: C13H22N4O9S. Mole weight: 410.40.
MM 46115
MM 46115 is produced by the strain of Actinomadura pelletieri. It has anti-parainfluenza virus 1 and 2 and anti-gram-positive bacteria activities. Synonyms: MM-46115; 17-O-(4-((3-Chloro-6-hydroxy-2-methylbenzoyl)amino)-2,3,4,6-tetradeoxy-3-(dimethylamino)-beta-D-lyxo-hexopyranosyl)-22-de(hydroxymethyl)-8,14,23-tridemethyl-12-ethyl-8-hydroxy-23-propylkijanolide. CAS No. 132054-37-6. Molecular formula: C50H67ClN2O10. Mole weight: 891.52.
MM 47755 is produced by the strain of greysporing streptomycete. It has anti-Gram-negative bacteria and fungi activity (100μg/ mL). Synonyms: 6-Deoxy-8-O-methylrabelomycin; (-)-3,4-Dihydro-3-hydroxy-8-methoxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione; MM-47755; Benz(a)anthracene-1,7,12(2H)-trione, 3,4-dihydro-3-hydroxy-8-methoxy-3-methyl-, (-)-. Grades: 95%. CAS No. 117620-87-8. Molecular formula: C20H16O5. Mole weight: 336.34.
MM 47755 (6-Desoxy-8-O-methylrabelomycin; (R)-3-Hydroxy-8-methoxy-3-methyl-3,4-dihydro-tetraphene-1,7,12(2H)-trione)
Antibiotic. Angucyclinone. Antibacterial and antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 117620-87-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MM 49721
It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria. Synonyms: MM-49721; Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-10,19-didechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)-. CAS No. 126985-52-2. Molecular formula: C72H87N9O28. Mole weight: 1526.50.
MM 54
MM 54 (compound 5) is a competitive antagonist at APJ , with an IC 50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1313027-43-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2271.
MM 54
MM 54 is an apelin receptor antagonist with IC50 value of 93 nM. It can antagonize the inhibitory effect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Synonyms: MM-54; MM54; H-Cys(1)-Arg-Pro-Arg-Leu-Cys(1)-Lys-His-Cys(2)-Arg-Pro-Arg-Leu-Cys(2)-OH; L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteinyl-L-lysyl-L-histidyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteine (1->6),(9->14)-bis(disulfide). Grades: ≥95%. CAS No. 1313027-43-8. Molecular formula: C70H121N29O15S4. Mole weight: 1737.15.
MM 55266
It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Synonyms: MM-55266; Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-(2-deoxy-2-((7-methyl-1-oxooctyl)amino)-alpha-D-glucopyranuronosyl)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-20-4. Molecular formula: C86H89Cl5N8O35. Mole weight: 1971.92.
MM-55268
It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Synonyms: Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-((2-deoxy-2-((1-oxodecyl)amino)-alpha-D-glucopyranuronosyl)amino)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-19-1. Molecular formula: C87H91Cl5N8O35. Mole weight: 1985.95.
MM 77 dihydrochloride
MM 77 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 159187-70-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MM 77 dihydrochloride
MM 77 dihydrochloride is a 5-HT1A receptor antagonist. Uses: Serotonin 5-ht1 receptor antagonists. Synonyms: MM 77 dihydrochloride; MM77 dihydrochloride; MM-77 dihydrochloride; 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine dihydrochloride. Grades: ≥95%. CAS No. 159187-70-9. Molecular formula: C19H27N3O3.2HCl. Mole weight: 418.36.
MMAE-d8
MMAE-d 8 is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Monomethyl auristatin E-d8; Deuterated labeled MMAE. CAS No. 2070009-72-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15162A.
MMAF Hydrochloride
MMAF Hydrochloride, a synthetic antineoplastic agent, is a tubulin polymerization inhibitor that inhibits cell division by blocking the polymerization of tubulin. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. Uses: Adcs cytotoxin. Synonyms: Monomethylauristatin F Hydrochloride; Monomethyl Auristatin F Hydrochloride; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine Hydrochloride; Monomethylauristatin Phenylalanine Hydrochloride; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, Hydrochloride (1:1); ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine Hydrochloride. Grades: >98%. CAS No. 1415246-68-2. Molecular formula: C39H66ClN5O8. Mole weight: 768.42.
MMAI
MMAI is a selective serotonin releaser that can be used in the research of mental illnesses [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Methoxy-6-methyl-2-aminoindan. CAS No. 136468-19-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W100249.
m,m'-Ditolylamine
m,m'-Ditolylamine. Group: Small molecule semiconductor building blockselectroluminescence materials polymers. CAS No. 626-13-1. Product ID: 3-methyl-N-(3-methylphenyl)aniline. Molecular formula: 197.27g/mol. Mole weight: C14H15N. CC1=CC(=CC=C1)NC2=CC=CC(=C2)C. InChI=1S/C14H15N/c1-11-5-3-7-13 (9-11)15-14-8-4-6-12 (2)10-14/h3-10, 15H, 1-2H3. CWVPIIWMONJVGG-UHFFFAOYSA-N.
Heterocyclic Organic Compound. CAS No. 1065-98-7. Purity: 0.96. Catalog: ACM1065987.
m-Methoxytopolin
m-Methoxytopolin. Group: Biochemicals. Grades: Highly Purified. CAS No. 75737-39-2. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C13H13N5O. US Biological Life Sciences.
Worldwide
m-Methoxytopolin-9-glucoside
m-Methoxytopolin-9-glucoside is an intricate and potent bioactive compound, used for studying a myriad of afflictions including cancer, inflammation and neurodegenerative disorders. Synonyms: 6-(3-Methoxybenzylamino)-9-b-Dglucopyranosylpurine. CAS No. 1226978-21-7. Molecular formula: C19H23N5O6. Mole weight: 417.42.
m-Methoxytopolin riboside
It can be used in biological study in influence of plant growth regulators on shoot proliferation and secondary metabolite production in micropropagated Huernia hystrix. Synonyms: N6-(m-Methoxybenzyl)adenosine; Mem-TR; 6-(3-Methoxybenzylamino)-9-b-D-ribofuranosylpurine; N6-(3-Methoxybenzyl)adenosine; N-(3-Methoxybenzyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; meta-Methoxytopolin Riboside; N-[(3-Methoxyphenyl)methyl]adenosine. Grades: ≥95%. CAS No. 101565-95-1. Molecular formula: C18H21N5O5. Mole weight: 387.39.
m-Methyl Atomoxetine Hydrochloride
M-Methyl Atomoxetine Hydrochloride is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: N-Methyl-γ-(3-methylphenoxy)benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride; rac-Atomoxetine EP Impurity D HCl; Atomoxetine USP Related Compound B; N-methyl-3-phenyl-3-(m-tolyloxy)propan-1-amine hydrochloride (1:1). Grades: ≥90%. CAS No. 873310-28-2. Molecular formula: C17H22ClNO. Mole weight: 291.81.
m-Methyl Atomoxetine Hydrochloride
m-Methyl Atomoxetine Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-γ - (3-methylphenoxy) benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride. Grades: Highly Purified. CAS No. 873310-28-2. Pack Sizes: 2.5mg. Molecular Formula: C17H22ClNO, Molecular Weight: 291.82. US Biological Life Sciences.
Worldwide
MMF
MMF. Group: Biochemicals. Grades: Purified. CAS No. 2756-87-8. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
MMGP1
MMGP1 is an antifungal peptide which was found to possess potent antifungal activity against C. albicans.
MMK 1
MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 = 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Some findings showed that the transient rise in intracellular free calcium induced by MMK-1 involves both a release of calcium from intracellular stores and an opening of channels in the plasma membrane. Synonyms: MMK 1; MMK1; MMK-1; (4S)-4-[[(2S)-2-amino-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid. CAS No. 271246-66-3. Molecular formula: C75H123N19O18S. Mole weight: 1610.97.
MMK 1
MMK 1. Group: Biochemicals. Grades: Purified. CAS No. 271246-66-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MMP-13 Inhibitor
MMP-13 Inhibitor is a potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 value of 8 nM. Synonyms: Collagenase-3 Inhibitor; Matrix Metalloproteinase-13 Inhibitor; 4,6-Pyrimidinedicarboxamide; N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide. Grades: ≥98%. CAS No. 544678-85-5. Molecular formula: C22H20F2N4O2. Mole weight: 410.4.
MMP2-IN-3
MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC 50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8 , with IC 50 values of 26.6, and 32 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 897799-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147746.
Mmp-2 inhibitor i
Heterocyclic Organic Compound. Alternative Names: MMP-2 Inhibitor I;Oleylhydroxamic acid. CAS No. 10335-69-0. Molecular formula: C18H35NO2. Mole weight: 297.48. Catalog: ACM10335690.
MMP-2 Inhibitor I
MMP-2 Inhibitor I is a reversible inhibitor of matrix metalloproteinase 2 (MMP-2) with Ki value of 1.6 μM. It attenuates cancer cell migration via inhibition of MMP-2. Synonyms: ?Matrix Metalloproteinase-2 Inhibitor I; cis-9-Octadecenoyl-N-hydroxylamide; Oleylhydroxamate; N-Hydroxyoleamide; OA-Hy; Oleoyl-N-hydroxylamide. Grades: ≥98%. CAS No. 10335-69-0. Molecular formula: C18H35NO2. Mole weight: 297.5.
MMP-2 Inhibitor II
MMP-2 Inhibitor II is an irreversible inhibitor of matrix metalloproteinase-2 (MMP-2) with Ki value of 2.4 μM. It also less potently inhibits MMP-1 and MMP-7. Synonyms: ?Matrix Metalloproteinase-2 Inhibitor II; (4- (4- (Methanesulfonamido) phenoxy) phenylsulfonyl) methyloxirane. Grades: ≥98%. CAS No. 869577-51-5. Molecular formula: C16H17NO6S2. Mole weight: 383.4.
MMP-2 Inhibitor IV (Bone Resorption Inhibitor, (4'-chlorobiphenyl-4ylsulfonamido) methylenediphosphonic Acid)
A cell-permeable, bisphosphonate derivative that displays nanomolar activity against MMP-2 (IC50=37nM), with good selectivity over MMP-8 (320nM), MMP-9 (>1uM), and MMP-14 (> 1uM). It is shown to inhibit osteoclast activity in a macrophage cell line, J774 (IC50=1.7uM), which is more potent compared with other bisphosphonates such as Alendronate, (IC50=30uM), and Zolendronate (7.8uM), without observable cytotoxicity in HepG2 cells. At 25uM, it abolishes the formation of actin rings, which are functional structures that are typical of resorbing osteoclasts, at activity levels comparable with those of zolendronic acid, inhibits bone resportion in vitro, and demonstrates cytotoxic properties in murine osteoclasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MMP-2/MMP-9-IN-1
MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase ( MMP-9 and MMP-2 ) inhibitor with IC 50 s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193807-58-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116399.
MMP-2/MMP-9 Inhibitor I
MMP-2/MMP-9 inhibitor I is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 310 and 240 nM, respectively. It blocks MMP-2/MMP-9-dependent invasion, tumor growth, and metastasis in both cell culture and mouse tumor models. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor I; 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanoic acid. Grades: ≥99%. CAS No. 193807-58-8. Molecular formula: C21H19NO4S. Mole weight: 381.4.
MMP-2/MMP-9 Inhibitor II
MMP-2/MMP-9 inhibitor II is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 17 and 30 nM, respectively. It was shown to suppress lung colonization of Lewis lung carcinoma cells and inhibit tumor-induced angiogenesis, tumor growth, and liver metastasis in mouse models. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II; (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide. Grades: ≥98%. CAS No. 193807-60-2. Molecular formula: C21H20N2O4S. Mole weight: 396.46.
MMP-2/MMP-9 Inhibitor III trifluoroacetate salt
MMP-2/MMP-9 inhibitor III is a cyclic peptide inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 10-20 μM for both. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grades: ≥95%. Molecular formula: C52H71N13O14S2·xCF3COOH. Mole weight: 1166.33.
MMP-3 Inhibitor
MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with Ki value of 95 nM. Synonyms: Matrix Metalloproteinase-3 Inhibitor; N-acetyl-L-arginyl-L-cysteinyl-glycyl-L-valyl-L-prolyl-L-isoasparagine. Grades: ≥95%. CAS No. 158841-76-0. Molecular formula: C27H46N10O9S. Mole weight: 686.78.
MMP-3 Inhibitor VIII
MMP-3 inhibitor VIII is a cell-permeable inhibitor of matrix metalloproteinase-3 (MMP-3) with Ki value of 23 nM. It also inhibits mouse macrophage metalloelastase MME/MMP-12. Synonyms: Matrix Metalloproteinase-3 Inhibitor VIII; Stromelysin-1 Inhibitor VIII; N-Hydroxy-2(R)-{[(4-methoxyphenyl)sulfonyl]-[benzylamino]}-4-methylpentanamide. Grades: ≥95%. CAS No. 208663-26-7. Molecular formula: C20H26N2O5S. Mole weight: 406.5.
MMP-8 Inhibitor I
MMP-8 Inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinase-8 (MMP-8) with IC50 value of 4 nM. MMP-8 is a neutrophil collagenase that cleaves interstitial collagens. MMP-8 is associated with diseases including arthritis, cancer, osteoporosis and arteriosclerosis. Synonyms: Matrix Metalloproteinase-8 Inhibitor I; N-hydroxy-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide. Grades: ≥95%. CAS No. 236403-25-1. Molecular formula: C17H18N2O5S. Mole weight: 362.4.
MMP-9-IN-9
MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC 50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 206549-55-5. Pack Sizes: 500 μg. Product ID: HY-116302.
MMP-9 Inhibitor I
MMP-9 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinase-9 (MMP-9) with IC50 value of 5 nM, respectively. Synonyms: Matrix Metalloproteinase-9 Inhibitor I; 2-[Benzyl(4-methoxyphenylsulfonyl)amino]-3-methyl-5-(diethylaminomethyl)benzohydroximic acid. Grades: ≥95%. CAS No. 1177749-58-4. Molecular formula: C27H33N3O5S. Mole weight: 511.6.
MMP-9 Inhibitor II (MMP-9 PEX Inhibitor)
This compound is a cell-permeable, selective, and reversible thiopyrimidone MMP-9 allosteric inhibitor that binds specifically to the non-catalytic site of MMP-9 at the PEX domain with a =2.1uM and thereby disrupts MMP-9 homodimerization and its cross-talk with CD44 and the EGFR-MAPK signaling pathway. It does not bind to the PEX domain of MMP-2 or MT1-MMP and it is shown to decrease MMP-9 mediated cell migration in COS-1 cells at 100uM. Also, it inhibits cell migration and invasion of HT-1080 and MDA-MB-435 human cancer cells in a dose-dependent manner from 0.1 to 100M, without altering MMP-9 expression or proteolytic activity in HT-1080 cells. In addition, it attenuates both primary tumor growth and metastasis in vivo in a mouse model without obvious toxicity (20mg/kg, 6 days/week, i.v. and i.t.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MMP-9/MMP-13 Inhibitor I
MMP-9/MMP-13 inhibitor I is a selective and cell-permeable inhibitor of matrix metalloproteinases MMP-9/MMP-13 with IC50 values of 0.9 nM for both. It also less potently inhibits MMP-1, MMP-3, and MMP-7. Synonyms: Matrix Metalloproteinase-9/Matrix Metalloproteinase-13 Inhibitor I; N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide. Grades: ≥98%. CAS No. 204140-01-2. Molecular formula: C25H25N3O6S. Mole weight: 495.6.
MMP Inhibitor II
MMP Inhibitor II (compound 4e) is a potent, reversible pan- MMP inhibitor with IC 50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 203915-59-7. Pack Sizes: 1 mg. Product ID: HY-119423.
MMP Inhibitor II
MMP Inhibitor II is an inhibitor of matrix metalloproteinase MMP-1/MMP-3/MMP-7/MMP-9 with IC50 values of 24, 18.4, 30 and 2.7 nM, respectively. Synonyms: Matrix Metalloproteinase Inhibitor II; NHDDPC; PG 117025; PGE 4410186; N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl-1,3-diazinane-2-carboxamide. Grades: ≥95%. CAS No. 203915-59-7. Molecular formula: C21H27N3O8S2. Mole weight: 513.6.
MMP Inhibitor I trifluoroacetate salt
MMP inhibitor I is an inhibitor of matrix metalloproteinase MMP-1/MMP-2/MMP-3 with IC50 values of 1.3, 30, and 150 μM, respectively. Synonyms: FN 439; Matrix Metalloproteinase Inhibitor I. Grades: ≥95%. Molecular formula: C23H35N6O6·xCF3COOH. Mole weight: 491.56.
MMPIP
MMPIP hydrochloride is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 = 26 and 610 nM). MMPIP also exhibits intrinsic activity and acts as an inverse agonist. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride. Grades: ≥98% by HPLC. CAS No. 479077-02-6. Molecular formula: C19H15N3O3. Mole weight: 333.3.
A potent negative allosteric modulator highly selective for mGlu7 receptors (IC50 = 15nM). No effect on other subtype mGlu receptors. Frequently used in studies of alcohol and cocaine addition, depression, anxiety and stress related disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 479077-02-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MMPIP hydrochloride
MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It was demonstrated to reduce pain responses and affective/cognitive impairments in neuropathic pain conditions. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-C]pyridin-4(5H)-one hydrochloride. Grades: ≥98%. CAS No. 1215566-78-1. Molecular formula: C19H15N3O3·HCl. Mole weight: 369.8.
MMPIP hydrochloride
MMPIP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 479077-02-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
MMPIP hydrochloride
MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 ( mGluR7 ) selective antagonist ( K B values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215566-78-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103111.
MMPSI
MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC 50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220509-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103346.
MMPX
MMPX. Group: Biochemicals. Grades: Purified. CAS No. 78033-08-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MMPX
MMPX is a specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase (IC50 = 5.2 μM). It causes an increase in cGMP but not cAMP, prolonging signal transduction for cGMP-dependent pathways. Synonyms: 8-Methoxymethyl-3-isobutyl-1-methylxanthine; MMPX; 8-METHOXYMETHYL-1-METHYL-3-(2-METHYLPROPYL)XANTHINE; 8-METHOXYMETHYL-3-ISOBUTYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-3-ISOBUTYRYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-IBMX. CAS No. 78033-08-6. Molecular formula: C12H18N4O3. Mole weight: 266.3.
MMs02943764
MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 ( IC 50 =35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2 , and induces K562 cell cycle arrest [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 708287-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158968.
MMSE
MMSE. Group: Biochemicals. Alternative Names: 3-Methoxymethyl-16a,17b-epiestriol-O-cyclic sulfone. Grades: Highly Purified. CAS No. 177714-21-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C17H15NO5S. US Biological Life Sciences.
Worldwide
Mmtc
Heterocyclic Organic Compound. Alternative Names: adrenoglomerulotropin;6-METHOXYTETRAHYDROHARMAN;1,2,3,4-Tetrahydro-6-methoxy-1-methyl-9H-pyrido[3,4-b]indole;1-Methyl-6-methoxy-1,2,3,4-tetrahydro-β-carboline;2,3,4,9-Tetrahydro-6-methoxy-1-methyl-1H-pyrido[3,4-b]indole;6-methoxy-1-methyl-2,3,4,9-tetrahy. CAS No. 1210-56-6. Molecular formula: C13H16N2O. Catalog: ACM1210566.
m-MTDATA
Organic Light Emitting Diode (OLED). Alternative Names: 4,4',4''-Tris(N-3-methylphenyl-N-phenyl-amino)-triphenylamine. CAS No. 124729-98-2. Molecular formula: C57H48N4. Mole weight: 789.02 g/mol. Catalog: ACM124729982.
MMV390048 is a novel antimalarial compound and it can competitively inhibit the binding of only a single protein, P. falciparum PI4 kinase, to the beads. MV390048 can become a child-friendly drug candidate for uncomplicated malaria that could be given as one single dose, completing the treatment in just one day. In May 2016, Phase I/II clinical trials in Malaria (In volunteers) in Australia was on-going. Uses: Malaria. Synonyms: UNII-0Z5T00JJ10;5-(4-(methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine;MMV390048; MMV-390048; MMV 390048; MMV-048; MMV 048; MMV048. Grades: 98%. CAS No. 1314883-11-8. Molecular formula: C18H14F3N3O2S. Mole weight: 393.38.
MMV688533
MMV688533 is an antimalarial agent with rapid anti-plasmodial activity and effective single-dose activity against Plasmodium falciparum infection in humanized mouse models. MMV688533 can inhibit the activity of asexual blood stage parasites with an IC 50 value of 1.3 nM. MMV688533 exhibits excellent pharmacokinetic properties and safety [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260904-47-8. Pack Sizes: 1 mg. Product ID: HY-148178.