A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Prostaglandin E1 | 1mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H34O5. CAS No. 745-65-3. Prepack ID 13337083-1mg. Molecular Weight 354.48. See USA prepack pricing. |  |
| Prostaglandin e1-[5,6-3h(N)] | Prostaglandin e1-[5,6-3h(N)]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [5,6(N)-3H]PROSTAGLANDIN E1;PGE1 [5,6-3H]-;PROSTAGLANDIN E1 [5,6-3H]-;PROSTAGLANDIN E1-[5,6-3H(N)]. Product Category: Heterocyclic Organic Compound. CAS No. 20045-36-7. Molecular formula: C20H32O5T2. Mole weight: 358.5. Product ID: ACM20045367. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Prostaglandin E2 | Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Group: Natural products. Alternative Names: PGE2; Dinoprostone. CAS No. 363-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952. |  |
| Prostaglandin E2-[3,3,4,4-d4] | Labelled Prostaglandin E2. Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Synonyms: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid-d4; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid-d4; (-)-Prostaglandin E2-d4; (15S)-Prostaglandin E2-d4; Cervidil-d4; Cerviprime-d4; Cerviprost-d4; Dinoprostone-d4; Minprostin E2-d4; PGE2-d4; Prepidil-d4; Primiprost-d4; Prostin E2-d4; l-PGE2-d4. CAS No. 34210-10-1. Molecular formula: C20H28D4O5. Mole weight: 356.50. |  |
| prostaglandin-E2 9-reductase | Reduces prostaglandin E2 to prostaglandin F2&alpha. A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds. May be identical with EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Enzyme Commission Number: EC 1.1.1.189. CAS No. 42613-35-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0091; prostaglandin-E2 9-reductase; EC 1.1.1.189; 42613-35-4; PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Cat No: EXWM-0091. |  |
| Prostaglandin E2 (Dinoprostone) | The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. Inhibits NLRP3 by acting through receptor EP4 activation that increases cAMP and phosphorylates NLRP3 at serine 295 through PKA. PKA phosphorylation of NLRP3 inhibits the NLRP3 ATPase activity, which is required for assembly of NLRP3-ASC complexes. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid; (-)-Prostaglandin E2; (15S)-Prostaglandin E2; Cervidil; Cerviprime; Cerviprost; Dinoprostone; Minprostin E2; PGE2; Prepidil. Grades: Highly Purified. CAS No. 363-24-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??O?. US Biological Life Sciences. |  Worldwide |
| Prostaglandin E2 Ethanolamide-d4 | Prostaglandin E2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; Prostamide E2; PGE2 ethanolamide. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences. | Worldwide |
| prostaglandin-endoperoxide synthase | This enzyme acts both as a dioxygenase and as a peroxidase. Group: Enzymes. Synonyms: prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Enzyme Commission Number: EC 1.14.99.1. CAS No. 39391-18-9. COX-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1031; prostaglandin-endoperoxide synthase; EC 1.14.99.1; 39391-18-9; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: EXWM-1031. | |
| Prostaglandin EP2 Receptor Antagonist, TG6-10-1 ( (E) -N- (2- (2- (trifluoromethyl) -1H-indol-1-yl) ethyl) -3- (3, 4, 5-trimethoxyphenyl) acrylamide, EP2 Antagonist, TG6-10-1) | A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb = 17.8nM). Exhibits about 300-fold selectivity for the EP2 receptor over human EP3, EP4, and IP receptors, about 100- fold selectivity over human EP1, 25-fold selectivity against human FP and TP, and 10-fold selectivity against human DP1 receptors. Does not affect the activity of about 40 enzymes, ion channels, receptors, and neurotransmitters even at higher concentrations (10uM). Shown to significantly reduce the induction of several inflammatory cytokines and chemokines and reduces the opening of blood-brain barrier during neuronal inflammation. Displays good pharmacokinetic properties with a half-life of 1.6 h and brain to plasma ratio of 1.6 in a murine model (5mg/kg i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. | Worldwide |
| prostaglandin-E synthase | Brings about the opening of the epidioxy bridge. Requires glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Enzyme Commission Number: EC 5.3.99.3. CAS No. 52227-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5511; prostaglandin-E synthase; EC 5.3.99.3; 52227-79-9; prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Cat No: EXWM-5511. | |
| Prostaglandin F1a | Prostaglandin F1a is a compound that has the effect of contracting smooth muscle and lowering blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 745-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113459. | |
| Prostaglandin F2a | Prostaglandin F2a. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic acid; (+)-Prostaglandin F2a. Grades: Highly Purified. CAS No. 551-11-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H34O5. US Biological Life Sciences. | Worldwide |
| Prostaglandin F2α | Prostaglandin F2α. Group: Biochemicals. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin F2α-[d4] | Prostaglandin F2α-[d4] is a PGF2αR activator. Synonyms: Prostaglandin F2α D4. Grade: 95% atom D. CAS No. 34210-11-2. Molecular formula: C20H30D4O5. Mole weight: 358.51. | |
| Prostaglandin F2α-d9 | Prostaglandin F2α-d9. Group: Biochemicals. Alternative Names: (5Z, 9α, 11α, 13E, 15S)-9, 11, 15-Trihydroxy-prosta-5, 13-dien-1-oic Acid-d9; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid-d9; (+)-Prostaglandin F2α-d9; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid-d9; 9α, 11α, 15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid-d9; 9α,11α-PGF2-d9; 9α,11α-PGF2α-d9; Amoglandin-d9; Croniben-d9; Cyclosin-d9; Cyclosin-d9 (pharmaceutical); Dinifertin-d9; Dinoprost-d9; Enzaprost-d9; Enzaprost F-d9; Glandin N; PGF2a-d9; PGF2α-d9; Panacelan-d9; Prostaglandin F2-d9; Prostaglandin F2a-d9; Prostamate-d9; Prostarmon F-d9; Prostin F 2 Alpha-d9; Protamodin-d9; U 14583-d9. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H25D9O5, Molecular Weight: 363.54. US Biological Life Sciences. | Worldwide |
| Prostaglandin F2α Tromethamine Salt | One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both. Group: Biochemicals. Alternative Names: (5Z, 9α, 11α, 13E, 15S)-9, 11, 15-Trihydroxyprosta-5, 13-dien-1-oic Acid 2-Amino-2-(hydroxymethyl)-1,3-propanediol; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid Tromethamine; (+)-Prostaglandin F2α Tromethamine; 9α, 11α, 15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid Tromethamine; 9α,11α-PGF2 Tromethamine; 9α,11α-PGF2α Tromethamine; Prostaglandin F2α-tham; THAM PGF2α; Tromethamine Prostaglandin F2α; U 14583E; U 14585. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin F(2)(a) tris salt | Prostaglandin F(2)(a) tris salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 25mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin F2? ethanolamide | ?98%. Group: Fluorescence/luminescence spectroscopy. |  |
| Prostaglandin F2? methyl ester | ~5 mg/mL in methyl acetate, ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| prostaglandin-F synthase | Reduces prostaglandin D2 and prostaglandin H2 to prostaglandin F2; prostaglandin D2 is not an intermediate in the reduction of prostaglandin H2. Also catalyses the reduction of a number of carbonyl compounds, such as 9,10-phenanthroquinone and 4-nitroacetophenone. Group: Enzymes. Synonyms: prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. PGF synthetase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0090; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9; prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Cat No: EXWM-0090. | |
| Prostaglandin F Synthase from human, Recombinant | PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways. Applications: Prostaglandin f synthase (pgf synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. prostaglandin f synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. pgf synthase is also used to study kidney and renal cell carcinoma. Group: Enzymes. Synonyms: prostaglandin-D2 11-reduc. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. Purity: > 90% (SDS-PAGE). PGF synthetase. Mole weight: mol wt ~37 kDa. Storage: -70°C. Source: E. coli. Species: Human. prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; prostaglandin-D2 11-reductase; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9. Cat No: NATE-0552. | |
| Prostaglandin F Synthase human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Prostaglandin G2 | ?95% (HPLC), acetone solution. Group: Fluorescence/luminescence spectroscopy. | |
| Prostaglandin H2 | ?95% (HPLC), acetonitrile solution. Group: Fluorescence/luminescence spectroscopy. | |
| Prostaglandin H2 | Prostaglandin H2 (PGH2), a potent vasoconstrictor, is produced by the conversion of Arachidonic acid (AA). Prostaglandin H2 is asubstrate for the production of Prostaglandins (PGs) and thromboxanes (TXs) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGH2. CAS No. 42935-17-1. Pack Sizes: 10 μg (283.71 μM * 100 μL in Acetone); 50 μg (283.71 μM * 500 μL in Acetone); 100 μg (283.71 μM * 1 mL in Acetone). Product ID: HY-136500. | |
| Prostaglandin I2 sodium salt | ?96% (HPLC), synthetic, powder. Group: Fluorescence/luminescence spectroscopy. | |
| Prostaglandin I2, Sodium Salt (PGI2, Prostacyclin) | Potent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Exhibits cytoprotective and fibrinolytic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| prostaglandin-I synthase | A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2 into prostaglandin I2 (prostacyclin). Group: Enzymes. Synonyms: prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Enzyme Commission Number: EC 5.3.99.4. CAS No. 65802-86-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5512; prostaglandin-I synthase; EC 5.3.99.4; 65802-86-0; prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Cat No: EXWM-5512. | |
| Prostaglandin J2 | Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with K i s of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC 50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PGJ2. CAS No. 60203-57-8. Pack Sizes: 500 μg (14.95 mM * 100 μL in Methyl acetate). Product ID: HY-113366. | |
| PROSTAGLANDINS | PROSTAGLANDINS. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PROSTAGLANDINS;Einecs 234-237-8. Product Category: Heterocyclic Organic Compound. CAS No. 11000-26-3. Product ID: ACM11000263. Alfa Chemistry ISO 9001:2015 Certified. | |
| prostamide/prostaglandin F2α synthase | The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2&alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. Group: Enzymes. Synonyms: prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Enzyme Commission Number: EC 1.11.1.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0502; prostamide/prostaglandin F2α synthase; EC 1.11.1.20; prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Cat No: EXWM-0502. | |
| Prostanozol | Prostanozol. Group: Biochemicals. Alternative Names: (5a,17b)-17-[(Tetrahydro-2H-pyran-2-yl)oxy]-2'H-androst-2-eno[3,2-c]pyrazole. Grades: Highly Purified. CAS No. 1186001-41-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C25H38N2O2. US Biological Life Sciences. | Worldwide |
| Prostate Microvascular Endothelial Cells, Human (Frozen) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Prostate Microvascular Endothelial Cells, Human (T-25 flask) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| Prostate Specific Antigen-1 (153-161) | Prostate Specific Antigen-1 (153-161) is a bioactive peptide of Prostate Specific Antigen-1. Prostate-specific antigen is a protein made by cells in the prostate gland (both normal cells and cancer cells). PSA is mostly found in semen, but a small amount is also found in blood. Synonyms: PSA-1 (153-161). | |
| Prostate Specific Antigen (146-154) | Prostate Specific Antigen (146-154) is a truncated fragment of Prostate Specific Antigen. Prostate-specific antigen is a protein made by cells in the prostate gland (both normal cells and cancer cells). PSA is mostly found in semen, but a small amount is also found in blood. Synonyms: PSA (146-154); gamma-seminoprotein (146-154); kallikrein-3 (146-154); P-30 antigen (146-154). | |
| Prostate-specific antigen (165-174) | Prostate-specific antigen (165-174) is a peptide corresponding to residues 165-174 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (165-174); prostatic specific acid phosphatase (165-174). | |
| Prostate-specific antigen (178-187) | Prostate-specific antigen (178-187) is a peptide corresponding to residues 178-187 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (178-187); prostatic specific acid phosphatase (178-187). | |
| Prostate Specific Antigen-?1-Antichymotrypsin Complex human | ?99% (SDS-PAGE), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Prostatic acid phosphatase (112-120) | Prostatic acid phosphatase (112-120) is a peptide corresponding to residues 112-120 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (112-120); prostatic specific acid phosphatase (112-120). | |
| Prostatic acid phosphatase (18-26) | Prostatic acid phosphatase (18-26) is a peptide corresponding to residues 18-26 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (18-26); prostatic specific acid phosphatase (18-26). | |
| Prostatic acid phosphatase (299-307) | Prostatic acid phosphatase (299-307) is a peptide corresponding to residues 299-307 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (299-307); prostatic specific acid phosphatase (299-307). | |
| Prostatic acid phosphatase from Human, recombinant | ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Group: Enzymes. Synonyms: Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Enzyme Commission Number: EC 3.1.3.2. CAS No. 9001-77-8. Purity: > 95% by SDS-PAGE. Apase. Mole weight: 41.8 kDa. Activity: >100,000 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: Baculovirus. Species: Human. Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Cat No: NATE-1673. | |
| Prostratin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Prostratin | Prostratin, a natural terpenoid compound, is a PKC activator, with a K i of 12.5 nM and shows inhibitory effect on HIV-1. Uses: Scientific research. Group: Natural products. CAS No. 60857-08-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107421. | |
| Prostratin | Prostratin. Group: Biochemicals. Alternative Names: (1aR, 1bS, 4aR, 7aS, 7bR, 8R, 9aS)-9a-(Acetyloxy)-1, 1a, 1b, 4, 4a, 7a, 7b, 8, 9, 9a-decahydro-4a, 7b-dihydroxy-3-(hydroxymethyl)-1, 1, 6, 8-tetramethyl-5H-cyclopropa[3, 4]benz[1, 2-e]azulen-5-one. Grades: Highly Purified. CAS No. 60857-08-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H30O6. US Biological Life Sciences. | Worldwide |
| Prosultiamine | Prosultiamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 59-58-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Pro-survival Compound, DDD00033325 | A cell-permeable, pyrrolidine small molecule that promotes single human embryonic stem cell survival up to 20-fold over background (EC50=3.9uM), with equal or higher potency than Y-27632 in 5 cell lines (SA461, SA181, SA167, SA121 and SA002) tested at 10uM. An in vitro high-content screening assay, which profiles a panel of more than 70 protein kinases, indicates that this small molecule is more selective than Y-27632 and only displays an inhibitory effect toward ROCK2 (> 83% inhibition, ROCK1 was not included in the panel) and PRK2 (76% inhibition) at 10uM. Furthermore, it exhibits less cytotoxicity at a greater concentration of 30uM than Y-27632 without marked adverse effects for up to 120 hours. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?, Molecular Weight: 293.37. US Biological Life Sciences. | Worldwide |
| PROTAC AR/AR-V7 degrader-1 | PROTAC AR/AR-V7 degrader-1 (27c) is a PROTAC-based and dual AR, AR-V7 degrader, with DC50 values of 2.67 and 2.64 ?M for AR and AR-V7, respectively. PROTAC AR/AR-V7 degrader-1 (27c) induces apoptosis (Red: AR antagonist; Blue: E3 ligase ligand; Black: linker)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2841308-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162412. | |
| PROTAC AR Degrader-8 | PROTAC AR Degrader-8 (Compound NP18) is the PROTAC degrader for androgen receptor ( AR ), that degrades AR-FL with DC 50 of 0.018 μM and 0.14 μM in 22Rv1 cell and LNCaP cell, degrades AR-V7 with DC 50 of 0.026 μM in 22Rv1 cell. PROTAC AR Degrader-8 inhibits the proliferation of cancer cell 22Rv1 and LNCaP with IC 50 of 0.038 μM and 1.11 μM. PROTAC AR Degrader-8 arrests cell cycle at G2/M phase, induces apoptosis in 22Rv1 cell. PROTAC AR Degrader-8 exhibits anticancer efficacy in mouse and zebrafish model [1]. (Pink: ligand for target protein AR ligand-33 (HY-170330); Black: linker (HY-W007731); Blue: ligand for E3 ligase Cereblon (HY-14658)). Uses: Scientific research. Group: Signaling pathways. CAS No. 3044108-04-2. Pack Sizes: 1 mg. Product ID: HY-170329. | |
| PROTAC Bcl2 degrader-1 | PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 ?M; DC50, 3.0 ?M) and Mcl-1 (IC50, 11.81 ?M) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1[1] (Blue: CRBN ligand, Black: linker?Pink: Mcl-1/Bcl-2 inhibitor, Nap-1). Uses: Scientific research. Group: Signaling pathways. CAS No. 2378801-85-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125876. | |
| PROTAC B-Raf degrader 1 | PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2364367-27-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111758. | |
| PROTAC BRAF-V600E degrader-1 | PROTAC BRAF-V600E degrader-1 (compound 23) is a potent PROTAC BRAF-V600E degrader whlie no degradation activity against BRAF-WT. PROTAC BRAF-V600E degrader-1 exhibits Kd values of 2.4 nM and 2 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-1 degrades BRAF-V600E via the ubiquitin-proteasome system (UPS) and inhibits the growth of melanoma cells[1]. (In the molecular structure, target protein ligand: BI-882370 (HY-107779), red part; E3 ubiquitin enzyme ligand: Pomalidomide (HY-10984), blue part; PROTAC linker: G007-LK (HY-12438), black part. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417296-84-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-137487. | |
| PROTAC BRD4 Degrader-10 | PROTAC BRD4 Degrader-10, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 1.3 and 18 nM, respectively. Synonyms: S-(3-(((((3R,5S)-1-((S)-15-(tert-butyl)-1-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulen-9-yl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)butan-2-yl) methanesulfonothioate. Grade: 98%. CAS No. 2417370-49-9. Molecular formula: C59H71F2N9O15S4. Mole weight: 1312.50. | |
| PROTAC BRD4 Degrader-11 | PROTAC BRD4 Degrader-11 is a PROTAC linked by ligands for von Hippel-Lindau and BRD4. It is conjugated with STEAP1 and CLL1 antibodies to degrade BRD4 protein in PC3 prostate cancer cells with DC50s of 0.23 nM and 0.38 nM, respectively. Synonyms: S-((R)-1-(((((3R,5S)-1-((S)-2-(11-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamido)undecanamido)-3,3-dimethylbutanoyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)propan-2-yl) methanesulfonothioate. Grade: 98%. Molecular formula: C61H75F2N9O12S4. Mole weight: 1292.56. | |
| PROTAC BRD4 Degrader-12 | PROTAC BRD4 Degrader-12, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.39 and 0.24 nM, respectively. Synonyms: S-(3-(((((3R,5S)-1-((S)-2-(11-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamido)undecanamido)-3,3-dimethylbutanoyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)butan-2-yl) methanesulfonothioate. Grade: 98%. CAS No. 2417370-90-0. Molecular formula: C62H77F2N9O12S4. Mole weight: 1306.58. | |
| PROTAC BRD4 Degrader-13 | PROTAC BRD4 Degrader-13, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.025 and 6.0 nM, respectively. CAS No. 2417370-71-7. Molecular formula: C68H85F2N11O17P2S2. Mole weight: 1492.54. | |
| PROTAC BRD4 Degrader-8 | PROTAC BRD4 Degrader-8 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026420-38-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138555. | |
| PROTAC BRD4 Degrader-9 | PROTAC BRD4 Degrader-9 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. It can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50 values of 0.86 nM and 7.6 nM, respectively. Synonyms: S-(1-(((((3R,5S)-1-((S)-15-(tert-butyl)-1-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulen-9-yl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)-2-methylpropan-2-yl) methanesulfonothioate. Grade: 98%. CAS No. 2417370-42-2. Molecular formula: C59H71F2N9O15S4. Mole weight: 1312.5. | |
| PROTAC CDK2/9 Degrader-1 | PROTAC CDK2/9 Degrader-1 (Compound F3) is a potent dual degrader for CDK2 (DC50=62 nM) and CDK9 (DC50=33 nM). PROTAC CDK2/9 Degrader-1 suppresses prostate cancer PC-3 cell proliferation (IC50=0.12 μM) by effectively blocking the cell cycle in S and G2/M phases. PROTAC CDK2/9 Degrader-1 is a PROTAC by tethering CDK inhibitor with Cereblon ligand[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2408641-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130709. | |
| PROTAC ERα Degrader-1 | PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha ( ERα ) degrader. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417369-94-7. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112098. | |
| PROTAC EZH2 Degrader-1 | PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2641601-67-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147525. | |
| PROTAC GPX4 degrader-1 | PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 ?M in HT1080 cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2916433-81-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149236. | |
| PROTAC HK2 Degrader-1 | PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine (HY-B0486) as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide (HY-14658) as a CRBN ligand-linked PROTAC. PROTAC HK2 Degrader-1 selectively inhibits the proliferation of breast cancer cells by forming a ternary complex through the ubiquitin-proteasome system to degrade Hexokinase 2 (HK2) protein leading to mitochondrial damage and cell death. PROTAC HK2 Degrader-1 effectively inhibits breast tumor growth and reduces the colonic side effects of cisplatin for breast cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033812-84-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155008. | |
| PROTAC IDO1 Degrader-1 | PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to Cereblon E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 ?M). PROTAC IDO1 Degrader-1 moderately improves the tumor-killing activity of H ER2 CAR-T cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2488851-89-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131911. | |
| PROTAC JAK1 degrader 1 | PROTAC JAK1 degrader 1 degrader 1 (compound 10c) is an effective and selective PROTAC JAK1 degrader with a DC50 of 214 nM. PROTAC JAK1 degrader 1 has antitumor activity. (Structure Note: PINK, JAK1 ligand 1 (HY-10961); Blue, VHL ligand Thalidomide (HY-14658); Black, linker)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3052553-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-162608. | |
| PROTAC K-Ras Degrader-4 | PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway[1]. (Pink: ligand for target protein pan-KRAS degrader 1 (HY-162960); Black: linker (HY-159790); Blue: ligand for E3 ligase VHL (HY-W998248)). Uses: Scientific research. Group: Signaling pathways. CAS No. 2938169-99-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-159788. | |
| PROTAC KRAS G12D degrader 1 | PROTAC KRAS G12D degrader 1 (compound 8o) is a potent, rapid, and selective degrader of protac KRASG12D with DC50 of 38.06 nM. PROTAC KRAS G12D degrader 1 showes significant antitumor efficacy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033583-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-161176. | |
| PROTAC YAP degrader-1 | PROTAC YAP degrader-1 (compound YZ-6) is a PROTAC targeting YAP and also inhibits the nuclear localization of YAP. PROTAC YAP degrader-1 is composed of PROTAC target protein ligand NSC682769 (HY-168017) (red part) and E3 ubiquitin ligase ligand + Linker conjugate (R,S,R)-AHPC-PEG2-C2-boc (HY-168019) (blue+black part), in which the PROTAC Linker used is Acid-PEG2-C2-Boc (HY-140480) and the target protein ligand activity control is Demethyl-NSC682769 (HY-168018)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3058483-58-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168016. | |
| proTAME | proTAME, a cell-permeable proagent form of TAME, is an anaphase promoting complex/cyclosome (APC/C) inhibitor. proTAME causes cell cycle arrest in metaphase[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1362911-19-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124955. | |
Our database is helping our users find suppliers everyday.
