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Product
Powdered andrographis extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered ashwagandha extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Asian Ginseng Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Powdered Bacopa Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Bilberry Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Powdered Black Cohosh Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Black Pepper Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Cat?s Claw Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Powdered Cellulose Powdered cellulose occurs as a white or almost white, odorless and tasteless powder of various particle sizes, ranging from a freeflowing fine or granular dense powder, to a coarse, fluffy, nonflowing material. Synonyms: Cellulose, Powdered; Alpha-cellulose; Arbocel; cellulosi pulvis; E460; Elcema; KC Flock; Microcel 3E-150; Sanacel; Sanacel Pharma; Sancel-W; Solka-Floc. CAS No. 9004-34-6. Product ID: PE0367. Molecular formula: (C6H10O5)n, n?500. Mole weight: ?243 000 Since cellulose is extracted from natural polymers, the chain lengths can vary, as can the molecular weight. Category: Adsorbents; Glidants; Suspending Agentss; Diluents; Disintegrating Agentss. Product Keywords: Suspending Agents; Adsorbents; PE0367; Powdered Cellulose; Adsorbents; Glidants; Suspending Agentss; Diluents; Disintegrating Agentss; (C6H10O5)n, n?500; 9004-34-6. UNII: SMD1X3XO9M. Chemical Name: Cellulose. Grade: Pharmceutical Excipients. Administration route: Oral; Dental; Sublingual; Oral; Topical. Dosage Form: Toothpaste, tablets (including sustained and controlled release preparations, etc.), capsules, drops, dry suspensions, etc. Stability and Storage Conditions: Powdered cellulose is a stable, slightly hygroscopic substance; it should be kept in an airtight container in a cool, dry place. Commonly used amount and the maximum amount: Capsule filler: 0~100%; tablet binder: 5%~25%; tablet disintegrant: 5%~15%; tablet glidant: 1%~2%. … CD Formulation
Powdered Cellulose United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Centella Asiatica Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Chaste Tree Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Chinese Salvia Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Decaffeinated Green Tea Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Echinacea Angustifolia Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Echinacea Purpurea Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Eleuthero Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Forskohlii Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Garcinia Hydroxycitrate Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered ginger United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Holy Basil Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered kava extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Malabar-Nut-Tree, Leaf Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered milk thistle extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Phyllanthus Amarus Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Red Clover Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Rosemary Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered Rosemary Hydrophilic Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Powdered St. John?s Wort Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Powdered Valerian Extract United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
p-Oxalotoluidide p-Oxalotoluidide. Group: Biochemicals. Alternative Names: N1, N2-Bis (4-methylphenyl) ethanediamide; N, N'-Bis (4-methylphenyl) ethanediamide; NSC 401961. Grades: Highly Purified. CAS No. 3299-61-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C16H16N2O2. US Biological Life Sciences. USBiological 8
Worldwide
p-Oxanisidide p-Oxanisidide. Group: Biochemicals. Alternative Names: N1, N2-Bis (4-methoxyphenyl) ethanediamide; N,N'-Bis(4-methoxyphenyl)oxamide; N,N'-Di-p-anisylamide. Grades: Highly Purified. CAS No. 3299-63-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C16H16N2O4. US Biological Life Sciences. USBiological 8
Worldwide
Pozanicline Pozanicline, a pyridine derivative, has been found to be a nicotinic receptor modulator that was once studied in Alzheimer's disease as a neuroprotective agent. Synonyms: Pozanicline; ABT-089; ABT 089; ABT089; A-87089; A-87089.0; Pozanicline; UNII-CL2002R563; CHEMBL127071; Pozanicline (USAN); 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine. Grades: 98%. CAS No. 161417-03-4. Molecular formula: C11H16N2O. Mole weight: 192.26. BOC Sciences 9
Pozanicline dihydrochloride Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor ( nAChR ) agonist with a K i of 16.7 nM for binding to [ 3 H]cytisine sites [1]. Pozanicline is an α4β2 -selective nAChR agonist, which binds to rat brain α4β2 nAChR with a K i of 17 nM while binding to α7 nAChR is insignificant [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-089 dihydrochloride. CAS No. 161416-61-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110160. MedChemExpress MCE
Pozelimab Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3918. CAS No. 2096328-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99786. MedChemExpress MCE
Poziotinib Poziotinib, also known as HM781-36B and NOV120101, is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. HM781-36B irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. EGFRs, cell surface receptor tyrosine kinases, are often upregulated in a variety of cancer cell types and play key roles in cellular proliferation and survival. Synonyms: HM781-36B; NOV120101; NOV-120101; NOV 120101; Poziotinib. CAS No. 1092364-38-9. Molecular formula: C23H21Cl2FN4O3. Mole weight: 491.344. BOC Sciences 10
Poziotinib Poziotinib (HM781-36B) is an orally active, irreversible pan- HER inhibitor, which effectively inhibits EGFR wt , HER-2 and HER-4 with IC 50 s of 3.2, 5.3 and 23.5 nM, respectively. Poziotinib (HM781-36B) also shows excellent inhibitory activities against mutated EGFRs, including EGFR T790M and EGFR L858R/T790M , with IC 50 s of 4.2 and 2.2 nM, respectively. Excellent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM781-36B; NOV120101. CAS No. 1092364-38-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15730. MedChemExpress MCE
Poziotinib Hydrochloride Poziotinib, also known as HM781-36B and NOV120101, is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. HM781-36B irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. EGFRs, cell surface receptor tyrosine kinases, are often upregulated in a variety of cancer cell types and play key roles in cellular proliferation and survival. Synonyms: Poziotinib HCl; NOV120101 hydrochloride; HM 781-36B hydrochloride. CAS No. 1429757-68-5. Molecular formula: C23H22Cl3FN4O3. Mole weight: 527.80. BOC Sciences 8
PP1 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PP1 PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC 50 of 5 and 6 nM for Lck and Fyn, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1872; EI 275. CAS No. 172889-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13804. MedChemExpress MCE
PP1 PP1 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM), and Src (IC50 = 170 nM) without significantly affecting the activity of EGFR kinase (IC50 = 250 nM), JAK2 (IC50 = 50 μM), or ZAP-70 (IC50 ≥ 0.6 μM). Synonyms: PP1; PP 1; PP1. Grades: >98%. CAS No. 172889-26-8. Molecular formula: C16H19N5. Mole weight: 281.36. BOC Sciences 11
PP 1 PP 1. Group: Biochemicals. Grades: Purified. CAS No. 172889-26-8. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
PP102 PP102 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp), and has antibacterial activity against both gram-negative and gram-positive bacteria, but no activity against fungi. Grades: ≥95%. BOC Sciences 4
PP113 PP113 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp), and has antibacterial activity against both gram-negative and gram-positive bacteria, but no activity against fungi. Grades: >98%. BOC Sciences 4
PP121 PP121 is a multitargeted dual receptor tyrosine kinases inhibitor. PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyrosine kinases and phosphatidylinositol-3-OH kinases. Synonyms: PP121; PP 121; PP-121. CAS No. 1092788-83-4. Molecular formula: C17H17N7. Mole weight: 319.372. BOC Sciences 10
PP121 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PP121 PP121 is a multi-targeted kinase inhibitor with IC50s of 10, 60, 12, 14, 2 nM for mTOR, DNK-PK, VEGFR2, Src, PDGFR, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092788-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10372. MedChemExpress MCE
PP 121 PP 121. Group: Biochemicals. Grades: Purified. CAS No. 1092788-83-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
P, P'-[ (1, 2-Phenylene) bis (methylene) ]bisphosphonic Acid P,P,P',P'-tetraethyl ester P, P'-[ (1, 2-Phenylene) bis (methylene) ]bisphosphonic Acid P,P,P',P'-tetraethyl ester. Group: Biochemicals. Alternative Names: (o-Phenylenedimethylene) diphosphonic Acid Tetraethyl Ester; [1, 2-Phenylenebis (methylene) ]bisphosphonic Acid Tetraethyl Ester; Tetraethyl o-Xylylenediphosphonate. Grades: Highly Purified. CAS No. 42092-05-7. Pack Sizes: 1g. Molecular Formula: C16H28O6P2, Molecular Weight: 378.34. US Biological Life Sciences. USBiological 3
Worldwide
PP13 PP13 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp). It has antibacterial activity against E. coli, B. subtilis, S. aureus, S. lutea and B. pumilu (MIC 8-23 μM), but no activity against fungi. Synonyms: Gly-Ala-Ala-Arg-Lys-Ser-Ile-Arg-Leu-His-Arg-Leu-Tyr-Thr-Trp-Lys-Ala-Thr-Ile-Tyr-Thr-Arg. Grades: ≥97%. Molecular formula: C121H197N39O29. Mole weight: 2662.15. BOC Sciences 4
PP1 (4-Amino-5-(methylphenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine) Highly potent and selective Scr family tyrosine kinase inhibitor. Shows anti-Ras cancer potential by blocking Ras-induced activation of PAK1. Antitumor compound. RIP2 inhibitor. Blocks TGF-beta-mediated cellular responses. Group: Biochemicals. Alternative Names: 4-Amino-5-(methylphenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine. Grades: Highly Purified. CAS No. 172889-26-8. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
PP1A, active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP1 Analog II, 1NM-PP1 - CAS 221244-14-0 PP1 Analog II, CAS 221244-14-0, is a cell-permeable PP1 analog that acts as a potent, reversible, selective, ATP-competitive inhibitor of mutant over wild-type kinases. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PP1 Analog III, 3-MB-PP1 - CAS 956025-83-5 PP1 Analog III, 3-MB-PP1 primarily used in Inhibition. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP1 Analog IV, 3-IB-PP1 (3-Iodobenzyl PP1 Analog) A cell-permeable enlarged PP1 analog that acts as a potent, ATP-competitive and reversible inhibitor of asAkt1/2/3 (IC50=28, 240 and 120nM, respectively) over wtAkt1/2/3 (IC50= >10uM). Shown to hyperphosphorylate Akt-Ser473 and -Thr308 in HEK293 cells coexpressed with myr-HA-asAkt1 or myr-HA-asAkt1/2/3 with no effect on pGSK-3bSer9 levels and wtAkt expressing cells. Also, specifically blocks the inhibitory function of membrane asCsk with diminished activity towards wtCsk, induces phosphorylation of Lck-Tyr394 and ERK1/2 in primary mouse T cells (EC50 ~0.5uM) and rapidly activates T cell receptor signaling. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C16H18IN5, Molecular Weight: 407.3. US Biological Life Sciences. USBiological 4
Worldwide
PP1 Analog V, 2,3-DMB-PP1 (4-Amino-1-tert-butyl-3- (2, 3-dimethylbenzyl) pyrazolo[3, 4-d]pyrimidine, 1-tert-Butyl-3-(2,3-dimethylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Syk ASKA Inhibitor II, PDK1 ASKA Inhibitor) A cell-permeable 3-MB-PP1 analog that is more effective than 3-MB-PP1 in inhibiting SykM442A S505A ASKA- (analog-sensitive kinase alleles) mediated cellular calcium flux (98% vs. 20% inhibition, respectively, by 1uM 2,3-DMB-PP1 or 3-MB-PP1) in Syk MASA-expressing DT40 cells. Also shown to selectively inhibit L159G ASKA, but not wt, PDK1-dependent GSK3&alpha Ser21 and S6 Ser235/236 phosphorylation upon IGF1 stimulation in mES cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 956026-24-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
PP1B, active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP2 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP2 PP2 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 4 nM), p59fynT (IC50 = 5 nM), Hck (IC50 = 5 nM), and Src (IC50 = 100 nM). Synonyms: PP-2; PP 2; AG 1879; AG-1879; AG1879. CAS No. 172889-27-9. Molecular formula: C15H16ClN5. Mole weight: 301.77. BOC Sciences 8
PP2 PP2 is a reversible and ATP-competitive Src family kinases inhibitor with IC 50 s of 4 and 5 nM for Lck and Fyn , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1879. CAS No. 172889-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13805. MedChemExpress MCE
PP2 PP2, also known as AG 1879, is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM). Despite its extensive use as a Src-selective inhibitor, recent research has shown that PP2 is non-selective and inhibits many other kinases with similar affinities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PP2; PP-2; PP 2; AG 1879; AG-1879; AG1879. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 172889-27-9. Molecular formula: C15H16ClN5. Mole weight: 301.77. Purity: >98%. IUPACName: 1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Canonical SMILES: NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(Cl)C=C3)=NC=N1. Product ID: ACM172889279. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PP 2 PP 2. Group: Biochemicals. Alternative Names: AGL 1879; PP 2 (enzyme inhibitor); Src kinase inhibitor PP2; 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grades: Highly Purified. CAS No. 172889-27-9. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C15H16ClN5, Molecular Weight: 301.77. US Biological Life Sciences. USBiological 3
Worldwide
PP242 PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM. PP242 also shows residual (micromolar) activity against panel of tyrosine kinases. But PP242 was much less active against other PI3K family members with IC50 of 2, 2.2, 0.1, 1.3 and 0.41 μM for p110α, p110β, p110δ, p110γ and DNA-PK, respectively. Synonyms: PP 242; PP-242; Torkinib. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.345. BOC Sciences 8
PP 242 PP 242. Group: Biochemicals. Alternative Names: 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol. Grades: Highly Purified. CAS No. 1092351-67-1. Pack Sizes: 10mg. Molecular Formula: C16H16N6O, Molecular Weight: 308.339999999999. US Biological Life Sciences. USBiological 3
Worldwide
PP242 (2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol) A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC?? = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092351-67-1. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
PP242 hydrate ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP2 (4-Amino-5-(4-chlorophenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine, AG 1879) Highly potent and selective Scr family tyrosine kinase inhibitor. Reduces cancer metastasis. Apoptotic. Antitumor compound. RIP2 inhbitor. Blocks TGF-beta-mediated cellular responses. Autophagy modulator. Group: Biochemicals. Alternative Names: 4-Amino-5-(4-chlorophenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine. Grades: Highly Purified. CAS No. 172889-27-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H16ClN5, Molecular Weight: 301.8. US Biological Life Sciences. USBiological 3
Worldwide
PP2A Activating Ligand, ITH12246 A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. USBiological 4
Worldwide
PP2A-?, active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PP2C-?, active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3

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